Result of FASTA (ccds) for
pFN21AE3980
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3980, 529 aa
1>>>pF1KE3980 529 - 529 aa - 529 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.1646+/-0.000696; mu= 19.9050+/- 0.042
mean_var=83.8180+/-16.757, 0's: 0 Z-trim(110.7): 97 B-trim: 66 in 1/48
Lambda= 0.140090
statistics sampled from 11642 (11790) to 11642 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.709), E-opt: 0.2 (0.362), width: 16
Scan time: 3.290
The best scores are: opt bits E(32554)
CCDS8534.1 KCNA6 gene_id:3742|Hs108|chr12 ( 529) 3570 731.3 6.4e-211
CCDS8536.1 KCNA5 gene_id:3741|Hs108|chr12 ( 613) 1247 261.9 1.5e-69
CCDS827.1 KCNA2 gene_id:3737|Hs108|chr1 ( 499) 1236 259.6 6.1e-69
CCDS8535.1 KCNA1 gene_id:3736|Hs108|chr12 ( 495) 1200 252.3 9.4e-67
CCDS41629.1 KCNA4 gene_id:3739|Hs108|chr11 ( 653) 1199 252.2 1.3e-66
CCDS55625.1 KCNA2 gene_id:3737|Hs108|chr1 ( 356) 907 193.0 5e-49
CCDS828.2 KCNA3 gene_id:3738|Hs108|chr1 ( 575) 904 192.6 1.1e-48
CCDS12755.1 KCNA7 gene_id:3743|Hs108|chr19 ( 456) 864 184.4 2.5e-46
CCDS826.1 KCNA10 gene_id:3744|Hs108|chr1 ( 511) 824 176.3 7.2e-44
CCDS10945.1 KCNG4 gene_id:93107|Hs108|chr16 ( 519) 576 126.2 9e-29
CCDS13418.1 KCNB1 gene_id:3745|Hs108|chr20 ( 858) 576 126.4 1.3e-28
CCDS13436.1 KCNG1 gene_id:3755|Hs108|chr20 ( 513) 573 125.6 1.4e-28
CCDS6209.1 KCNB2 gene_id:9312|Hs108|chr8 ( 911) 566 124.4 5.5e-28
CCDS1809.1 KCNG3 gene_id:170850|Hs108|chr2 ( 436) 537 118.3 1.9e-26
CCDS12019.1 KCNG2 gene_id:26251|Hs108|chr18 ( 466) 536 118.1 2.2e-26
CCDS6447.1 KCNV2 gene_id:169522|Hs108|chr9 ( 545) 535 118.0 2.9e-26
CCDS42674.1 KCNG3 gene_id:170850|Hs108|chr2 ( 425) 532 117.3 3.7e-26
CCDS12793.1 KCNC3 gene_id:3748|Hs108|chr19 ( 757) 531 117.3 6.4e-26
CCDS7827.1 KCNC1 gene_id:3746|Hs108|chr11 ( 511) 521 115.1 2e-25
CCDS44547.1 KCNC1 gene_id:3746|Hs108|chr11 ( 585) 521 115.2 2.2e-25
CCDS9006.1 KCNC2 gene_id:3747|Hs108|chr12 ( 558) 512 113.3 7.4e-25
CCDS58255.1 KCNC2 gene_id:3747|Hs108|chr12 ( 583) 512 113.3 7.6e-25
CCDS9005.1 KCNC2 gene_id:3747|Hs108|chr12 ( 613) 512 113.4 7.9e-25
CCDS58257.1 KCNC2 gene_id:3747|Hs108|chr12 ( 618) 512 113.4 8e-25
CCDS58256.1 KCNC2 gene_id:3747|Hs108|chr12 ( 629) 512 113.4 8.1e-25
CCDS9007.1 KCNC2 gene_id:3747|Hs108|chr12 ( 638) 512 113.4 8.1e-25
CCDS5776.1 KCND2 gene_id:3751|Hs108|chr7 ( 630) 508 112.6 1.4e-24
CCDS14314.1 KCND1 gene_id:3750|Hs108|chrX ( 647) 506 112.2 1.9e-24
CCDS844.1 KCND3 gene_id:3752|Hs108|chr1 ( 636) 504 111.8 2.5e-24
CCDS843.1 KCND3 gene_id:3752|Hs108|chr1 ( 655) 504 111.8 2.5e-24
CCDS44193.1 KCNC4 gene_id:3749|Hs108|chr1 ( 626) 502 111.3 3.3e-24
CCDS821.1 KCNC4 gene_id:3749|Hs108|chr1 ( 635) 502 111.4 3.3e-24
CCDS13342.1 KCNS1 gene_id:3787|Hs108|chr20 ( 526) 480 106.8 6.3e-23
CCDS1692.1 KCNS3 gene_id:3790|Hs108|chr2 ( 491) 469 104.6 2.8e-22
CCDS6279.1 KCNS2 gene_id:3788|Hs108|chr8 ( 477) 446 99.9 6.8e-21
CCDS1676.1 KCNF1 gene_id:3754|Hs108|chr2 ( 494) 443 99.3 1.1e-20
CCDS6314.1 KCNV1 gene_id:27012|Hs108|chr8 ( 500) 435 97.7 3.3e-20
CCDS13521.1 KCNQ2 gene_id:3785|Hs108|chr20 ( 393) 294 69.1 1.1e-11
CCDS46629.1 KCNQ2 gene_id:3785|Hs108|chr20 ( 841) 294 69.4 1.8e-11
CCDS13518.1 KCNQ2 gene_id:3785|Hs108|chr20 ( 844) 294 69.4 1.8e-11
CCDS13519.1 KCNQ2 gene_id:3785|Hs108|chr20 ( 854) 294 69.4 1.8e-11
CCDS13520.1 KCNQ2 gene_id:3785|Hs108|chr20 ( 872) 294 69.4 1.9e-11
CCDS7736.1 KCNQ1 gene_id:3784|Hs108|chr11 ( 676) 284 67.3 6.3e-11
>>CCDS8534.1 KCNA6 gene_id:3742|Hs108|chr12 (529 aa)
initn: 3570 init1: 3570 opt: 3570 Z-score: 3900.2 bits: 731.3 E(32554): 6.4e-211
Smith-Waterman score: 3570; 100.0% identity (100.0% similar) in 529 aa overlap (1-529:1-529)
10 20 30 40 50 60
pF1KE3 MRSEKSLTLAAPGEVRGPEGEQQDAGDFPEAGGGGGCCSSERLVINISGLRFETQLRTLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS85 MRSEKSLTLAAPGEVRGPEGEQQDAGDFPEAGGGGGCCSSERLVINISGLRFETQLRTLS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 LFPDTLLGDPGRRVRFFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDIFLEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS85 LFPDTLLGDPGRRVRFFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDIFLEE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 IRFYQLGDEALAAFREDEGCLPEGGEDEKPLPSQPFQRQVWLLFEYPESSGPARGIAIVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS85 IRFYQLGDEALAAFREDEGCLPEGGEDEKPLPSQPFQRQVWLLFEYPESSGPARGIAIVS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 VLVILISIVIFCLETLPQFRVDGRGGNNGGVSRVSPVSRGSQEEEEDEDDSYTFHHGITP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS85 VLVILISIVIFCLETLPQFRVDGRGGNNGGVSRVSPVSRGSQEEEEDEDDSYTFHHGITP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 GEMGTGGSSSLSTLGGSFFTDPFFLVETLCIVWFTFELLVRFSACPSKPAFFRNIMNIID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS85 GEMGTGGSSSLSTLGGSFFTDPFFLVETLCIVWFTFELLVRFSACPSKPAFFRNIMNIID
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 LVAIFPYFITLGTELVQQQEQQPASGGGGQNGQQAMSLAILRVIRLVRVFRIFKLSRHSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS85 LVAIFPYFITLGTELVQQQEQQPASGGGGQNGQQAMSLAILRVIRLVRVFRIFKLSRHSK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 GLQILGKTLQASMRELGLLIFFLFIGVILFSSAVYFAEADDDDSLFPSIPDAFWWAVVTM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS85 GLQILGKTLQASMRELGLLIFFLFIGVILFSSAVYFAEADDDDSLFPSIPDAFWWAVVTM
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 TTVGYGDMYPMTVGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETEQEEQGQYTHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS85 TTVGYGDMYPMTVGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETEQEEQGQYTHV
430 440 450 460 470 480
490 500 510 520
pF1KE3 TCGQPAPDLRATDNGLGKPDFPEANRERRPSYLPTPHRAYAEKRMLTEV
:::::::::::::::::::::::::::::::::::::::::::::::::
CCDS85 TCGQPAPDLRATDNGLGKPDFPEANRERRPSYLPTPHRAYAEKRMLTEV
490 500 510 520
>>CCDS8536.1 KCNA5 gene_id:3741|Hs108|chr12 (613 aa)
initn: 1514 init1: 945 opt: 1247 Z-score: 1362.0 bits: 261.9 E(32554): 1.5e-69
Smith-Waterman score: 2056; 70.3% identity (81.0% similar) in 468 aa overlap (12-473:86-531)
10 20 30
pF1KE3 MRSEKSLTLAAPGEVRGPEGEQQDAGDFPEAGG------GG
: : : .... :: : : :
CCDS85 AQRDADSGVRPLPPLPDPGVRPLPPLPEELPRPRRPPPEDEEEEGD-PGLGTVEDQALGT
60 70 80 90 100 110
40 50 60 70 80 90
pF1KE3 GCCSSERLVINISGLRFETQLRTLSLFPDTLLGDPGRRVRFFDPLRNEYFFDRNRPSFDA
. .:. :::::::::::: ::. ::.::::::..:.:.::::::::::::::::::.
CCDS85 ASLHHQRVHINISGLRFETQLGTLAQFPNTLLGDPAKRLRYFDPLRNEYFFDRNRPSFDG
120 130 140 150 160 170
100 110 120 130 140 150
pF1KE3 ILYYYQSGGRLRRPVNVPLDIFLEEIRFYQLGDEALAAFREDEGCLPEGGEDEKPLPSQP
::::::::::::::::: ::.: .:::::::::::. :::::: . : .::::: .
CCDS85 ILYYYQSGGRLRRPVNVSLDVFADEIRFYQLGDEAMERFREDEGFIKE---EEKPLPRNE
180 190 200 210 220 230
160 170 180 190 200 210
pF1KE3 FQRQVWLLFEYPESSGPARGIAIVSVLVILISIVIFCLETLPQFRVDGRGGNNGGVSRVS
:::::::.:::::::: ::.:::::::::::::. :::::::.:: : : . :
CCDS85 FQRQVWLIFEYPESSGSARAIAIVSVLVILISIITFCLETLPEFR-DERE-----LLRHP
240 250 260 270 280
220 230 240 250 260 270
pF1KE3 PVSRGSQEEEEDEDDSYTFHHGITPGEMGTGGSSSLSTLGGSFFTDPFFLVETLCIVWFT
:. . . : : :. .. ... : ..::::.::: :..:::
CCDS85 PAPHQPPAPAPGANGS---------GVMAPPSGPTVAPLLPRTLADPFFIVETTCVIWFT
290 300 310 320 330
280 290 300 310 320 330
pF1KE3 FELLVRFSACPSKPAFFRNIMNIIDLVAIFPYFITLGTELVQQQEQQPASGGGGQNGQQA
::::::: ::::: .: ::::::::.::::::::::::::. ::::..::::::::::
CCDS85 FELLVRFFACPSKAGFSRNIMNIIDVVAIFPYFITLGTELA---EQQPGGGGGGQNGQQA
340 350 360 370 380 390
340 350 360 370 380 390
pF1KE3 MSLAILRVIRLVRVFRIFKLSRHSKGLQILGKTLQASMRELGLLIFFLFIGVILFSSAVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS85 MSLAILRVIRLVRVFRIFKLSRHSKGLQILGKTLQASMRELGLLIFFLFIGVILFSSAVY
400 410 420 430 440 450
400 410 420 430 440 450
pF1KE3 FAEADDDDSLFPSIPDAFWWAVVTMTTVGYGDMYPMTVGGKIVGSLCAIAGVLTIALPVP
:::::.. . : ::::::::::::::::::::: :.::::::::::::::::::::::::
CCDS85 FAEADNQGTHFSSIPDAFWWAVVTMTTVGYGDMRPITVGGKIVGSLCAIAGVLTIALPVP
460 470 480 490 500 510
460 470 480 490 500 510
pF1KE3 VIVSNFNYFYHRETEQEEQGQYTHVTCGQPAPDLRATDNGLGKPDFPEANRERRPSYLPT
::::::::::::::..::
CCDS85 VIVSNFNYFYHRETDHEEPAVLKEEQGTQSQGPGLDRGVQRKVSGSRGSFCKAGGTLENA
520 530 540 550 560 570
>>CCDS827.1 KCNA2 gene_id:3737|Hs108|chr1 (499 aa)
initn: 1794 init1: 891 opt: 1236 Z-score: 1351.2 bits: 259.6 E(32554): 6.1e-69
Smith-Waterman score: 2087; 69.5% identity (80.6% similar) in 489 aa overlap (20-503:17-460)
10 20 30 40 50 60
pF1KE3 MRSEKSLTLAAPGEVRGPEGEQQDAGDFPEAGGGGGCCSSERLVINISGLRFETQLRTLS
:. ::. : ::: :: ::.:::::::::::::.::.
CCDS82 MTVATGDPADEAAALPGHPQDTYD-PEADHE--CC--ERVVINISGLRFETQLKTLA
10 20 30 40 50
70 80 90 100 110 120
pF1KE3 LFPDTLLGDPGRRVRFFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDIFLEE
::.:::::: .:.:.::::::::::::::::::::::::::::::::::::::::: ::
CCDS82 QFPETLLGDPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDIFSEE
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE3 IRFYQLGDEALAAFREDEGCLPEGGEDEKPLPSQPFQRQVWLLFEYPESSGPARGIAIVS
::::.::.::. :::::: . : .:.::: . ::::::::::::::::::: :::::
CCDS82 IRFYELGEEAMEMFREDEGYIKE---EERPLPENEFQRQVWLLFEYPESSGPARIIAIVS
120 130 140 150 160
190 200 210 220 230 240
pF1KE3 VLVILISIVIFCLETLPQFRVDGRGGNNGGVSRVSPVSRGSQEEEEDEDDSYTFHHGITP
:.::::::: ::::::: :: .:.:: : . : .
CCDS82 VMVILISIVSFCLETLPIFR----------------------DENEDMHGSGVTFHTYSN
170 180 190 200
250 260 270 280 290 300
pF1KE3 GEMGTGGSSSLSTLGGSFFTDPFFLVETLCIVWFTFELLVRFSACPSKPAFFRNIMNIID
. .: :.: ::::::.::::::.::.::.:::: ::::: .:: :::::::
CCDS82 STIGYQQSTS--------FTDPFFIVETLCIIWFSFEFLVRFFACPSKAGFFTNIMNIID
210 220 230 240 250
310 320 330 340 350 360
pF1KE3 LVAIFPYFITLGTELVQQQEQQPASGGGGQNGQQAMSLAILRVIRLVRVFRIFKLSRHSK
.:::.::::::::::... :. .:.:::::::::::::::::::::::::::::
CCDS82 IVAIIPYFITLGTELAEKPED-------AQQGQQAMSLAILRVIRLVRVFRIFKLSRHSK
260 270 280 290 300 310
370 380 390 400 410 420
pF1KE3 GLQILGKTLQASMRELGLLIFFLFIGVILFSSAVYFAEADDDDSLFPSIPDAFWWAVVTM
::::::.::.::::::::::::::::::::::::::::::. .: :::::::::::::.:
CCDS82 GLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADERESQFPSIPDAFWWAVVSM
320 330 340 350 360 370
430 440 450 460 470 480
pF1KE3 TTVGYGDMYPMTVGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETEQEEQGQYTHV
:::::::: : :.::::::::::::::::::::::::::::::::::::: :::.:: .:
CCDS82 TTVGYGDMVPTTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETEGEEQAQYLQV
380 390 400 410 420 430
490 500 510 520
pF1KE3 T-CGQ-PA-PDLRATDNG--LGKPDFPEANRERRPSYLPTPHRAYAEKRMLTEV
: : . :. :::. . .. ..: :. :
CCDS82 TSCPKIPSSPDLKKSRSASTISKSDYMEIQEGVNNSNEDFREENLKTANCTLANTNYVNI
440 450 460 470 480 490
>>CCDS8535.1 KCNA1 gene_id:3736|Hs108|chr12 (495 aa)
initn: 2044 init1: 851 opt: 1200 Z-score: 1311.9 bits: 252.3 E(32554): 9.4e-67
Smith-Waterman score: 2015; 66.3% identity (80.9% similar) in 487 aa overlap (14-498:11-443)
10 20 30 40 50
pF1KE3 MRSEKSLTLAAPGEVRGPEGEQQDAGDFPEAGGGGG--CCSSERLVINISGLRFETQLRT
:. . :. :: :..:. . :: ::.:::::::::::::.:
CCDS85 MTVMSGENVDEASAAPGHPQD-GSYPRQADHDDHECC--ERVVINISGLRFETQLKT
10 20 30 40 50
60 70 80 90 100 110
pF1KE3 LSLFPDTLLGDPGRRVRFFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDIFL
:. ::.::::.: .:.:.:::::::::::::::::::::::::::::::::::::::.:
CCDS85 LAQFPNTLLGNPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDMFS
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE3 EEIRFYQLGDEALAAFREDEGCLPEGGEDEKPLPSQPFQRQVWLLFEYPESSGPARGIAI
:::.::.::.::. :::::: . :.:.::: . .:::::::::::::::::: :::
CCDS85 EEIKFYELGEEAMEKFREDEGFIK---EEERPLPEKEYQRQVWLLFEYPESSGPARVIAI
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE3 VSVLVILISIVIFCLETLPQFRVDGRGGNNGGVSRVSPVSRGSQEEEEDEDDSYTFHHGI
:::.:::::::::::::::... : .: : :. :.. ....
CCDS85 VSVMVILISIVIFCLETLPELKDD--KDFTGTVHRI--------------DNTTVIYN--
180 190 200 210
240 250 260 270 280 290
pF1KE3 TPGEMGTGGSSSLSTLGGSFFTDPFFLVETLCIVWFTFELLVRFSACPSKPAFFRNIMNI
...::::::.::::::.::.:::.::: ::::: ::.::::.
CCDS85 -----------------SNIFTDPFFIVETLCIIWFSFELVVRFFACPSKTDFFKNIMNF
220 230 240 250
300 310 320 330 340 350
pF1KE3 IDLVAIFPYFITLGTELVQQQEQQPASGGGGQNGQQAMSLAILRVIRLVRVFRIFKLSRH
::.:::.:::::::::...:. :.:.:.:: ::::::::::::::::::::::
CCDS85 IDIVAIIPYFITLGTEIAEQE--------GNQKGEQATSLAILRVIRLVRVFRIFKLSRH
260 270 280 290 300
360 370 380 390 400 410
pF1KE3 SKGLQILGKTLQASMRELGLLIFFLFIGVILFSSAVYFAEADDDDSLFPSIPDAFWWAVV
::::::::.::.:::::::::::::::::::::::::::::.. .: : :::::::::::
CCDS85 SKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEAEEAESHFSSIPDAFWWAVV
310 320 330 340 350 360
420 430 440 450 460 470
pF1KE3 TMTTVGYGDMYPMTVGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETEQEEQGQYT
.:::::::::::.:.::::::::::::::::::::::::::::::::::::: :::.:
CCDS85 SMTTVGYGDMYPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETEGEEQAQLL
370 380 390 400 410 420
480 490 500 510 520
pF1KE3 HVTCGQPAPDLRATDNGLGKPDFPEANRERRPSYLPTPHRAYAEKRMLTEV
::. .:.: :.:. :..
CCDS85 HVS----SPNL-ASDSDLSRRSSSTMSKSEYMEIEEDMNNSIAHYRQVNIRTANCTTANQ
430 440 450 460 470 480
>>CCDS41629.1 KCNA4 gene_id:3739|Hs108|chr11 (653 aa)
initn: 2031 init1: 864 opt: 1199 Z-score: 1309.2 bits: 252.2 E(32554): 1.3e-66
Smith-Waterman score: 2019; 65.9% identity (80.6% similar) in 501 aa overlap (20-503:148-613)
10 20 30 40
pF1KE3 MRSEKSLTLAAPGEVRGPEGEQQDAGDF-PEAGGGGG--------CCSS
:.. . :. :. :::: ::
CCDS41 LRELSEEEEDEEEEEEEEEEGRFYYSEDDHGDECSYTDLLPQDEGGGGYSSVRYSDCC--
120 130 140 150 160 170
50 60 70 80 90 100
pF1KE3 ERLVINISGLRFETQLRTLSLFPDTLLGDPGRRVRFFDPLRNEYFFDRNRPSFDAILYYY
::.:::.::::::::..::. ::.:::::: .:...::::::::::::::::::::::::
CCDS41 ERVVINVSGLRFETQMKTLAQFPETLLGDPEKRTQYFDPLRNEYFFDRNRPSFDAILYYY
180 190 200 210 220 230
110 120 130 140 150 160
pF1KE3 QSGGRLRRPVNVPLDIFLEEIRFYQLGDEALAAFREDEGCLPEGGEDEKPLPSQPFQRQV
::::::.::::::.::: ::..:::::.::: :::::: . : :... :: . :..:.
CCDS41 QSGGRLKRPVNVPFDIFTEEVKFYQLGEEALLKFREDEGFVRE--EEDRALPENEFKKQI
240 250 260 270 280 290
170 180 190 200 210 220
pF1KE3 WLLFEYPESSGPARGIAIVSVLVILISIVIFCLETLPQFRVDGRGGNNGGVSRVSPVSRG
::::::::::.::::::::::::::::::::::::::.:: : : . : .: :
CCDS41 WLLFEYPESSSPARGIAIVSVLVILISIVIFCLETLPEFR-DDR-------DLVMALSAG
300 310 320 330 340
230 240 250 260 270 280
pF1KE3 SQEEEEDEDDSYTFHHGITPGEMGTGGSSSLSTLGGSFFTDPFFLVETLCIVWFTFELLV
. :: : .. .. : . : ..:.::::.:::.:::::.::..:
CCDS41 G--------------HG---GLLNDTSAPHLENSGHTIFNDPFFIVETVCIVWFSFEFVV
350 360 370 380
290 300 310 320 330 340
pF1KE3 RFSACPSKPAFFRNIMNIIDLVAIFPYFITLGTELVQQQEQQPASGGGGQNGQQAMSLAI
: ::::. ::.:::::::.:.:.::::::::.:.::: .::.::. :::::.::
CCDS41 RCFACPSQALFFKNIMNIIDIVSILPYFITLGTDLAQQQ-----GGGNGQQ-QQAMSFAI
390 400 410 420 430 440
350 360 370 380 390 400
pF1KE3 LRVIRLVRVFRIFKLSRHSKGLQILGKTLQASMRELGLLIFFLFIGVILFSSAVYFAEAD
::.:::::::::::::::::::::::.::.::::::::::::::::::::::::::::::
CCDS41 LRIIRLVRVFRIFKLSRHSKGLQILGHTLRASMRELGLLIFFLFIGVILFSSAVYFAEAD
450 460 470 480 490 500
410 420 430 440 450 460
pF1KE3 DDDSLFPSIPDAFWWAVVTMTTVGYGDMYPMTVGGKIVGSLCAIAGVLTIALPVPVIVSN
. . : ::::::::::::::::::::: :.:::::::::::::::::::::::::::::
CCDS41 EPTTHFQSIPDAFWWAVVTMTTVGYGDMKPITVGGKIVGSLCAIAGVLTIALPVPVIVSN
510 520 530 540 550 560
470 480 490 500 510
pF1KE3 FNYFYHRETEQEEQGQYTH--VTCGQ-PAPDLR----ATDNGLG-KPDFPEANRERRPSY
::::::::::.::: : :. :.: :. :. .:...:: : .. :
CCDS41 FNYFYHRETENEEQTQLTQNAVSCPYLPSNLLKKFRSSTSSSLGDKSEYLEMEEGVKESL
570 580 590 600 610 620
520
pF1KE3 LPTPHRAYAEKRMLTEV
CCDS41 CAKEEKCQGKGDDSETDKNNCSNAKAVETDV
630 640 650
>>CCDS55625.1 KCNA2 gene_id:3737|Hs108|chr1 (356 aa)
initn: 995 init1: 589 opt: 907 Z-score: 993.7 bits: 193.0 E(32554): 5e-49
Smith-Waterman score: 1283; 61.0% identity (74.6% similar) in 354 aa overlap (20-373:17-323)
10 20 30 40 50 60
pF1KE3 MRSEKSLTLAAPGEVRGPEGEQQDAGDFPEAGGGGGCCSSERLVINISGLRFETQLRTLS
:. ::. : ::: :: ::.:::::::::::::.::.
CCDS55 MTVATGDPADEAAALPGHPQDTYD-PEADH--ECC--ERVVINISGLRFETQLKTLA
10 20 30 40 50
70 80 90 100 110 120
pF1KE3 LFPDTLLGDPGRRVRFFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDIFLEE
::.:::::: .:.:.::::::::::::::::::::::::::::::::::::::::: ::
CCDS55 QFPETLLGDPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDIFSEE
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE3 IRFYQLGDEALAAFREDEGCLPEGGEDEKPLPSQPFQRQVWLLFEYPESSGPARGIAIVS
::::.::.::. :::::: . :.:.::: . ::::::::::::::::::: :::::
CCDS55 IRFYELGEEAMEMFREDEGYIK---EEERPLPENEFQRQVWLLFEYPESSGPARIIAIVS
120 130 140 150 160
190 200 210 220 230 240
pF1KE3 VLVILISIVIFCLETLPQFRVDGRGGNNGGVSRVSPVSRGSQEEEEDEDDSYTFHHGITP
:.::::::: ::::::: :: .:.:: : . : .
CCDS55 VMVILISIVSFCLETLPIFR----------------------DENEDMHGSGVTFHTYSN
170 180 190 200
250 260 270 280 290 300
pF1KE3 GEMGTGGSSSLSTLGGSFFTDPFFLVETLCIVWFTFELLVRFSACPSKPAFFRNIMNIID
. .: :.: ::::::.::::::.::.::.:::: ::::: .:: :::::::
CCDS55 STIGYQQSTS--------FTDPFFIVETLCIIWFSFEFLVRFFACPSKAGFFTNIMNIID
210 220 230 240 250
310 320 330 340 350 360
pF1KE3 LVAIFPYFITLGTELVQQQEQQPASGGGGQNGQQAMSLAILRVIRLVRVFRIFKLSRHSK
.:::.::::::::::... :. .:.::::::::::::::: : : .. .. ..
CCDS55 IVAIIPYFITLGTELAEKPED-------AQQGQQAMSLAILRVIRLER--RPLQSQKSKR
260 270 280 290 300 310
370 380 390 400 410 420
pF1KE3 GLQILGKTLQASMRELGLLIFFLFIGVILFSSAVYFAEADDDDSLFPSIPDAFWWAVVTM
: : :. . . ..
CCDS55 GRQHLNTSHDCTLGINLVAGMTVQWTRASGPDDRQTPAVTTLHRMY
320 330 340 350
>>CCDS828.2 KCNA3 gene_id:3738|Hs108|chr1 (575 aa)
initn: 1828 init1: 894 opt: 904 Z-score: 987.7 bits: 192.6 E(32554): 1.1e-48
Smith-Waterman score: 2109; 68.9% identity (78.9% similar) in 508 aa overlap (19-501:63-529)
10 20 30
pF1KE3 MRSEKSLTLAAPGEVRGPEGEQQDAGDFPEAGG--GGGC---------
: : :.: : :: ::::
CCDS82 HTLVNHGYAEPAAGRELPPDMTVVPGDHLLEPEVADGGGAPPQGGCGGGGCDRYEPLPPS
40 50 60 70 80 90
40 50 60 70 80
pF1KE3 --------CSSERLVINISGLRFETQLRTLSLFPDTLLGDPGRRVRFFDPLRNEYFFDRN
: .::.:::::::::::::.:: ::.:::::: ::.:.:::::::::::::
CCDS82 LPAAGEQDCCGERVVINISGLRFETQLKTLCQFPETLLGDPKRRMRYFDPLRNEYFFDRN
100 110 120 130 140 150
90 100 110 120 130 140
pF1KE3 RPSFDAILYYYQSGGRLRRPVNVPLDIFLEEIRFYQLGDEALAAFREDEGCLPEGGEDEK
::::::::::::::::.:::::::.::: :::::::::.::. :::::: : :.:.
CCDS82 RPSFDAILYYYQSGGRIRRPVNVPIDIFSEEIRFYQLGEEAMEKFREDEGFLR---EEER
160 170 180 190 200
150 160 170 180 190 200
pF1KE3 PLPSQPFQRQVWLLFEYPESSGPARGIAIVSVLVILISIVIFCLETLPQFRVDGRGGNNG
::: . ::::::::::::::::::::::::::::::::::::::::::.:: .
CCDS82 PLPRRDFQRQVWLLFEYPESSGPARGIAIVSVLVILISIVIFCLETLPEFRDE-------
210 220 230 240 250 260
210 220 230 240 250 260
pF1KE3 GVSRVSPVSRGSQEEEEDEDDSYTFHHGITPGEMGTGGSSSLSTLGGSFFTDPFFLVETL
. :.: :: ::. ..:.:.: : :.: :.::::.::::
CCDS82 ---KDYPAST-SQ-------DSFE----------AAGNSTSGSRAGASSFSDPFFVVETL
270 280 290 300
270 280 290 300 310 320
pF1KE3 CIVWFTFELLVRFSACPSKPAFFRNIMNIIDLVAIFPYFITLGTELVQQQEQQPASGGGG
::.::.::::::: ::::: .: :::::.::.:::.::::::::::...: :
CCDS82 CIIWFSFELLVRFFACPSKATFSRNIMNLIDIVAIIPYFITLGTELAERQ------G---
310 320 330 340 350
330 340 350 360 370 380
pF1KE3 QNGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGKTLQASMRELGLLIFFLFIGVIL
::::::::::::::::::::::::::::::::::::.::.:::::::::::::::::::
CCDS82 -NGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVIL
360 370 380 390 400 410
390 400 410 420 430 440
pF1KE3 FSSAVYFAEADDDDSLFPSIPDAFWWAVVTMTTVGYGDMYPMTVGGKIVGSLCAIAGVLT
:::::::::::: : : :::::::::::::::::::::.:.:.::::::::::::::::
CCDS82 FSSAVYFAEADDPTSGFSSIPDAFWWAVVTMTTVGYGDMHPVTIGGKIVGSLCAIAGVLT
420 430 440 450 460 470
450 460 470 480 490 500
pF1KE3 IALPVPVIVSNFNYFYHRETEQEEQGQYTHV-TC---GQPAPDLRA--TDNGLGKPDFPE
::::::::::::::::::::: :::.:: :: .: .. : .:: ... :.: ..
CCDS82 IALPVPVIVSNFNYFYHRETEGEEQSQYMHVGSCQHLSSSAEELRKARSNSTLSKSEYMV
480 490 500 510 520 530
510 520
pF1KE3 ANRERRPSYLPTPHRAYAEKRMLTEV
CCDS82 IEEGGMNHSAFPQTPFKTGNSTATCTTNNNPNSCVNIKKIFTDV
540 550 560 570
>>CCDS12755.1 KCNA7 gene_id:3743|Hs108|chr19 (456 aa)
initn: 1931 init1: 860 opt: 864 Z-score: 945.4 bits: 184.4 E(32554): 2.5e-46
Smith-Waterman score: 1906; 63.4% identity (77.3% similar) in 497 aa overlap (36-529:10-456)
10 20 30 40 50 60
pF1KE3 SLTLAAPGEVRGPEGEQQDAGDFPEAGGGGGCCSSERLVINISGLRFETQLRTLSLFPDT
::: ::::.:..::::::. :::. ::::
CCDS12 MEPRCPPPCGCC--ERLVLNVAGLRFETRARTLGRFPDT
10 20 30
70 80 90 100 110 120
pF1KE3 LLGDPGRRVRFFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDIFLEEIRFYQ
:::::.:: ::.: : ::::::.::::::.:::::::::::::..::::.::::. ::
CCDS12 LLGDPARRGRFYDDARREYFFDRHRPSFDAVLYYYQSGGRLRRPAHVPLDVFLEEVAFYG
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE3 LGDEALAAFREDEGC-LPEGGEDEKPLPSQPFQRQVWLLFEYPESSGPARGIAIVSVLVI
:: ::: .:::::: .: :.::: . : ::.:::::.:::: :: .:.::::::
CCDS12 LGAAALARLREDEGCPVP----PERPLPRRAFARQLWLLFEFPESSQAARVLAVVSVLVI
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE3 LISIVIFCLETLPQFRVDGRGGNNGGVSRVSPVSRGSQEEEEDEDDSYTFHHGITPGEMG
:.:::.:::::::.:: : : :. :.. .. . : :. .
CCDS12 LVSIVVFCLETLPDFR-DDRDGT--GLAAAAAA-------------------GPFPAPL-
160 170 180 190
250 260 270 280 290 300
pF1KE3 TGGSSSLSTLGGSF-FTDPFFLVETLCIVWFTFELLVRFSACPSKPAFFRNIMNIIDLVA
.:::.. . :.::::.:::::: ::.::::::. .:::: ::.:.::.::.::
CCDS12 -NGSSQMPGNPPRLPFNDPFFVVETLCICWFSFELLVRLLVCPSKAIFFKNVMNLIDFVA
200 210 220 230 240
310 320 330 340 350 360
pF1KE3 IFPYFITLGTELVQQQEQQPASGGGGQNGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQ
:.:::..:::::..:. : ::::::::::::::::::::::::::::::::
CCDS12 ILPYFVALGTELARQR-------G---VGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQ
250 260 270 280 290
370 380 390 400 410 420
pF1KE3 ILGKTLQASMRELGLLIFFLFIGVILFSSAVYFAEADDDDSLFPSIPDAFWWAVVTMTTV
:::.::.:::::::::::::::::.::::::::::.: :: : :::..:::::::::::
CCDS12 ILGQTLRASMRELGLLIFFLFIGVVLFSSAVYFAEVDRVDSHFTSIPESFWWAVVTMTTV
300 310 320 330 340 350
430 440 450 460 470 480
pF1KE3 GYGDMYPMTVGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETEQEEQGQYTHVTCG
::::: :.:::::::::::::::::::.::::::::::.:::::::: :: :...::
CCDS12 GYGDMAPVTVGGKIVGSLCAIAGVLTISLPVPVIVSNFSYFYHRETEGEEAGMFSHVDM-
360 370 380 390 400 410
490 500 510 520
pF1KE3 QPAPDLRATDNG-LGKPDFPEANRERRPSYLPTPHRAYAEKRMLTEV
:: :.. :: : . :: :: : : :...:::
CCDS12 QPCGPLEGKANGGLVDGEVPE---------LPPPLWAPPGKHLVTEV
420 430 440 450
>>CCDS826.1 KCNA10 gene_id:3744|Hs108|chr1 (511 aa)
initn: 1906 init1: 811 opt: 824 Z-score: 901.0 bits: 176.3 E(32554): 7.2e-44
Smith-Waterman score: 1796; 64.4% identity (78.5% similar) in 452 aa overlap (26-474:68-473)
10 20 30 40 50
pF1KE3 MRSEKSLTLAAPGEVRGPEGEQQDAGDFPEAGGGGGCCSSE---RLVINISGLRF
::. . : .: :..:::.::::
CCDS82 KGRPGGSSFSNGKILISESTNHETAFSKLPGDYADPPGPEPVVLNEGNQRVIINIAGLRF
40 50 60 70 80 90
60 70 80 90 100 110
pF1KE3 ETQLRTLSLFPDTLLGDPGRRVRFFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNV
:::::::: ::.::::: .:..::: .::::::::::::::.:::::::::..:::.::
CCDS82 ETQLRTLSQFPETLLGDREKRMQFFDSMRNEYFFDRNRPSFDGILYYYQSGGKIRRPANV
100 110 120 130 140 150
120 130 140 150 160 170
pF1KE3 PLDIFLEEIRFYQLGDEALAAFREDEGCLPEGGEDEKPLPSQPFQRQVWLLFEYPESSGP
:.::: .:: ::.::.::. :::::: . . : ::.. ..:: ::::::::::.
CCDS82 PIDIFADEISFYELGSEAMDQFREDEGFIKD---PETLLPTNDIHRQFWLLFEYPESSSA
160 170 180 190 200 210
180 190 200 210 220 230
pF1KE3 ARGIAIVSVLVILISIVIFCLETLPQFRVDGRGGNNGGVSRVSPVSRGSQEEEEDEDDSY
::..:.:::::..:::.::::::::.:: : : : : : .
CCDS82 ARAVAVVSVLVVVISITIFCLETLPEFRED----------RELKVVR---------DPNL
220 230 240 250
240 250 260 270 280 290
pF1KE3 TFHHGITPGEMGTGGSSSLSTLGGSFFTDPFFLVETLCIVWFTFELLVRFSACPSKPAFF
.. : ..:. ..::::::.::. :::::::::..:: .:::: ::
CCDS82 NM---------------SKTVLSQTMFTDPFFMVESTCIVWFTFELVLRFVVCPSKTDFF
260 270 280 290 300
300 310 320 330 340 350
pF1KE3 RNIMNIIDLVAIFPYFITLGTELVQQQEQQPASGGGGQNGQQAMSLAILRVIRLVRVFRI
::::::::...:.::: :: ::::: : .:.. :: :::::::.:::::::::
CCDS82 RNIMNIIDIISIIPYFATLITELVQ--ETEPSA-------QQNMSLAILRIIRLVRVFRI
310 320 330 340 350
360 370 380 390 400 410
pF1KE3 FKLSRHSKGLQILGKTLQASMRELGLLIFFLFIGVILFSSAVYFAEADDDDSLFPSIPDA
::::::::::::::.::.::::::::::::::::::::::::::::.:. .: : ::::.
CCDS82 FKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEVDEPESHFSSIPDG
360 370 380 390 400 410
420 430 440 450 460 470
pF1KE3 FWWAVVTMTTVGYGDMYPMTVGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETEQE
:::::::::::::::: : : ::::::.::::::::::::::::::::::::::::::.:
CCDS82 FWWAVVTMTTVGYGDMCPTTPGGKIVGTLCAIAGVLTIALPVPVIVSNFNYFYHRETENE
420 430 440 450 460 470
480 490 500 510 520
pF1KE3 EQGQYTHVTCGQPAPDLRATDNGLGKPDFPEANRERRPSYLPTPHRAYAEKRMLTEV
:.
CCDS82 EKQNIPGEIERILNSVGSRMGSTDSLNKTNGGCSTEKSRK
480 490 500 510
>>CCDS10945.1 KCNG4 gene_id:93107|Hs108|chr16 (519 aa)
initn: 633 init1: 217 opt: 576 Z-score: 630.1 bits: 126.2 E(32554): 9e-29
Smith-Waterman score: 596; 28.3% identity (55.0% similar) in 491 aa overlap (41-493:59-491)
20 30 40 50 60 70
pF1KE3 APGEVRGPEGEQQDAGDFPEAGGGGGCCSSERLVINISGLRFETQLRTLSLFPDTLLGDP
....::..: :. ::. :: . :.
CCDS10 SPMETPSIKGLYYRRVRKVGALDASPVDLKKEILINVGGRRYLLPWSTLDRFPLSRLSKL
30 40 50 60 70 80
80 90 100 110 120
pF1KE3 GRRVRFFDPL----------RNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDIFLEE
: : .. . .:.::::. .: .:. . .: . :. : ::
CCDS10 -RLCRSYEEIVQLCDDYDEDSQEFFFDRSPSAFGVIVSFLAAGKLVLLQEMCALS-FQEE
90 100 110 120 130 140
130 140 150
pF1KE3 IRFYQLGD------------------EALAAF-REDEGCLPEGGEDEKPLPSQP----FQ
. .. . . : :: . ::: : . : ..: . .
CCDS10 LAYWGIEEAHLERCCLRKLLRKLEELEELAKLHRED--VLRQQRETRRPASHSSRWGLCM
150 160 170 180 190 200
160 170 180 190 200 210
pF1KE3 RQVWLLFEYPESSGPARGIAIVSVLVILISIVIFCLETLPQFRVDGRGGNNGGVSRVSPV
.. . : :.:. :.. .: .:.: . . : .:. :.:..:.
CCDS10 NRLREMVENPQSGLPGKVFACLSILFVATTAVSLCVSTMPDLRA----------------
210 220 230 240
220 230 240 250 260 270
pF1KE3 SRGSQEEEEDEDDSYTFHHGITPGEMGTGGSSSLSTLGGSFFTDPFFLVETLCIVWFTFE
::.. : . .. .:.:::.:..::..:
CCDS10 -----EEDQGECSRKCYY---------------------------IFIVETICVAWFSLE
250 260 270
280 290 300 310 320 330
pF1KE3 LLVRFSACPSKPAFFRNIMNIIDLVAIFPYFITLGTELVQQQEQQPASG--GGGQNGQQA
. .:: .: ::.. .::::..:: ::...:.. .:. : .: .:.. .
CCDS10 FCLRFVQAQDKCQFFQGPLNIIDILAISPYYVSLAV-----SEEPPEDGERPSGSSYLEK
280 290 300 310 320 330
340 350 360 370 380 390
pF1KE3 MSLAILRVIRLVRVFRIFKLSRHSKGLQILGKTLQASMRELGLLIFFLFIGVILFSSAVY
..: .:::.: .:.. ...:.::: ::: :: :.. ::.:::..:: ... ::: ::
CCDS10 VGL-VLRVLRALRILYVMRLARHSLGLQTLGLTVRRCTREFGLLLLFLAVAITLFSPLVY
340 350 360 370 380 390
400 410 420 430 440 450
pF1KE3 FAEADDDDSL-FPSIPDAFWWAVVTMTTVGYGDMYPMTVGGKIVGSLCAIAGVLTIALPV
:: .. : : ::: ..:::...::::::::: : .: :..:. ..:.: .:.:.
CCDS10 VAEKESGRVLEFTSIPASYWWAIISMTTVGYGDMVPRSVPGQMVALSSILSGILIMAFPA
400 410 420 430 440 450
460 470 480 490 500 510
pF1KE3 PVIVSNFNYFYHR-ETEQEE-QGQYTHVTCGQPAPDLRATDNGLGKPDFPEANRERRPSY
: .:.. : . . :::. :.. :. :: . . :
CCDS10 TSIFHTFSHSYLELKKEQEQLQARLRHLQNTGPASECELLDPHVASEHELMNDVNDLILE
460 470 480 490 500 510
520
pF1KE3 LPTPHRAYAEKRMLTEV
CCDS10 GPALPIMHM
529 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 22:44:35 2016 done: Sat Nov 5 22:44:35 2016
Total Scan time: 3.290 Total Display time: 0.090
Function used was FASTA [36.3.4 Apr, 2011]