FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE3976, 273 aa
  1>>>pF1KE3976 273 - 273 aa - 273 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.3542+/-0.000804; mu= 14.2716+/- 0.049
 mean_var=59.0589+/-12.140, 0's: 0 Z-trim(106.7): 41  B-trim: 363 in 1/51
 Lambda= 0.166890
 statistics sampled from 9102 (9136) to 9102 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.671), E-opt: 0.2 (0.281), width:  16
 Scan time:  2.330

The best scores are:                                      opt bits E(32554)
CCDS102.1 SPSB1 gene_id:80176|Hs108|chr1           ( 273) 1887 462.5 1.4e-130
CCDS3115.1 SPSB4 gene_id:92369|Hs108|chr3          ( 273) 1458 359.2 1.8e-99
CCDS8567.1 SPSB2 gene_id:84727|Hs108|chr12         ( 263)  884 221.0 6.8e-58
CCDS46985.1 FBXO45 gene_id:200933|Hs108|chr3       ( 286)  490 126.2 2.7e-29


>>CCDS102.1 SPSB1 gene_id:80176|Hs108|chr1                (273 aa)
 initn: 1887 init1: 1887 opt: 1887  Z-score: 2457.7  bits: 462.5 E(32554): 1.4e-130
Smith-Waterman score: 1887; 100.0% identity (100.0% similar) in 273 aa overlap (1-273:1-273)

               10        20        30        40        50        60
pF1KE3 MGQKVTGGIKTVDMRDPTYRPLKQELQGLDYCKPTRLDLLLDMPPVSYDVQLLHSWNNND
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 MGQKVTGGIKTVDMRDPTYRPLKQELQGLDYCKPTRLDLLLDMPPVSYDVQLLHSWNNND
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE3 RSLNVFVKEDDKLIFHRHPVAQSTDAIRGKVGYTRGLHVWQITWAMRQRGTHAVVGVATA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 RSLNVFVKEDDKLIFHRHPVAQSTDAIRGKVGYTRGLHVWQITWAMRQRGTHAVVGVATA
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE3 DAPLHSVGYTTLVGNNHESWGWDLGRNRLYHDGKNQPSKTYPAFLEPDETFIVPDSFLVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 DAPLHSVGYTTLVGNNHESWGWDLGRNRLYHDGKNQPSKTYPAFLEPDETFIVPDSFLVA
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE3 LDMDDGTLSFIVDGQYMGVAFRGLKGKKLYPVVSAVWGHCEIRMRYLNGLDPEPLPLMDL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 LDMDDGTLSFIVDGQYMGVAFRGLKGKKLYPVVSAVWGHCEIRMRYLNGLDPEPLPLMDL
              190       200       210       220       230       240

              250       260       270   
pF1KE3 CRRSVRLALGRERLGEIHTLPLPASLKAYLLYQ
       :::::::::::::::::::::::::::::::::
CCDS10 CRRSVRLALGRERLGEIHTLPLPASLKAYLLYQ
              250       260       270   

>>CCDS3115.1 SPSB4 gene_id:92369|Hs108|chr3               (273 aa)
 initn: 1458 init1: 1458 opt: 1458  Z-score: 1899.5  bits: 359.2 E(32554): 1.8e-99
Smith-Waterman score: 1458; 74.7% identity (90.5% similar) in 273 aa overlap (1-273:1-273)

               10        20        30        40        50        60
pF1KE3 MGQKVTGGIKTVDMRDPTYRPLKQELQGLDYCKPTRLDLLLDMPPVSYDVQLLHSWNNND
       ::::..:..:.:..:.:. :: :.::.: .  .:.::: ::::: ..  ::: :.:: .:
CCDS31 MGQKLSGSLKSVEVREPALRPAKRELRGAEPGRPARLDQLLDMPAAGLAVQLRHAWNPED
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE3 RSLNVFVKEDDKLIFHRHPVAQSTDAIRGKVGYTRGLHVWQITWAMRQRGTHAVVGVATA
       ::::::::.::.: :::::::::::.::::::..::::.:::.:  ::::::::::::::
CCDS31 RSLNVFVKDDDRLTFHRHPVAQSTDGIRGKVGHARGLHAWQINWPARQRGTHAVVGVATA
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE3 DAPLHSVGYTTLVGNNHESWGWDLGRNRLYHDGKNQPSKTYPAFLEPDETFIVPDSFLVA
        :::::::::.:::.. :::::::::.::::::::::. .::::: :::.: .:::.::.
CCDS31 RAPLHSVGYTALVGSDAESWGWDLGRSRLYHDGKNQPGVAYPAFLGPDEAFALPDSLLVV
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE3 LDMDDGTLSFIVDGQYMGVAFRGLKGKKLYPVVSAVWGHCEIRMRYLNGLDPEPLPLMDL
       ::::.:::::::::::.::::::::::::::::::::::::. :::.:::::::::::::
CCDS31 LDMDEGTLSFIVDGQYLGVAFRGLKGKKLYPVVSAVWGHCEVTMRYINGLDPEPLPLMDL
              190       200       210       220       230       240

              250       260       270   
pF1KE3 CRRSVRLALGRERLGEIHTLPLPASLKAYLLYQ
       ::::.: ::::.:: .: .:::: ::: :: ::
CCDS31 CRRSIRSALGRQRLQDISSLPLPQSLKNYLQYQ
              250       260       270   

>>CCDS8567.1 SPSB2 gene_id:84727|Hs108|chr12              (263 aa)
 initn: 879 init1: 417 opt: 884  Z-score: 1152.8  bits: 221.0 E(32554): 6.8e-58
Smith-Waterman score: 889; 50.9% identity (72.9% similar) in 273 aa overlap (1-273:1-263)

               10        20        30        40        50        60
pF1KE3 MGQKVTGGIKTVDMRDPTYRPLKQELQGLDYCKPTRLDLLLDMPPVSYDVQLLHSWNNND
       ::: . .: ..     :: . :  .:.    : :  :. ::. :: .  .:  :.:: .:
CCDS85 MGQTALAGGSS---STPTPQALYPDLS----C-PEGLEELLSAPPPDLGAQRRHGWNPKD
               10           20             30        40        50  

               70        80        90       100       110       120
pF1KE3 RSLNVFVKEDDKLIFHRHPVAQSTDAIRGKVGYTRGLHVWQITWAMRQRGTHAVVGVATA
        : :. :::   : :.:.:::::::. ::: ::.::::.:.:.: ..:::::::::::::
CCDS85 CSENIEVKEGG-LYFERRPVAQSTDGARGKRGYSRGLHAWEISWPLEQRGTHAVVGVATA
             60         70        80        90       100       110 

              130       140       150       160       170       180
pF1KE3 DAPLHSVGYTTLVGNNHESWGWDLGRNRLYHDGKNQPSKTYPAFLEPDETFIVPDSFLVA
        :::..  :..:.:.: ::::::.::..:::..:.  .  :::  .  : . ::. .::.
CCDS85 LAPLQTDHYAALLGSNSESWGWDIGRGKLYHQSKGPGAPQYPAGTQ-GEQLEVPERLLVV
             120       130       140       150        160       170

              190       200       210       220       230       240
pF1KE3 LDMDDGTLSFIVDGQYMGVAFRGLKGKKLYPVVSAVWGHCEIRMRYLNGLDPEPLPLMDL
       :::..:::.. . : :.: :::::::. :::.::::::.:..:.:::.    ::  :. :
CCDS85 LDMEEGTLGYAIGGTYLGPAFRGLKGRTLYPAVSAVWGQCQVRIRYLGERRAEPHSLLHL
              180       190       200       210       220       230

              250       260       270   
pF1KE3 CRRSVRLALGRERLGEIHTLPLPASLKAYLLYQ
        :  ::  ::  :::.. .:::: ..: :::::
CCDS85 SRLCVRHNLGDTRLGQVSALPLPPAMKRYLLYQ
              240       250       260   

>>CCDS46985.1 FBXO45 gene_id:200933|Hs108|chr3            (286 aa)
 initn: 441 init1: 162 opt: 490  Z-score: 639.5  bits: 126.2 E(32554): 2.7e-29
Smith-Waterman score: 490; 39.4% identity (69.4% similar) in 193 aa overlap (36-227:93-280)

          10        20        30        40        50         60    
pF1KE3 TGGIKTVDMRDPTYRPLKQELQGLDYCKPTRLDLLLDMPPVSYDVQLL-HSWNNNDRSLN
                                     : :.: ..:  .  .. . :....:: : :
CCDS46 CKHWYRCLHGDENSEVWRSLCARSLAEEALRTDILCNLPSYKAKIRAFQHAFSTNDCSRN
             70        80        90       100       110       120  

           70        80        90       100       110       120    
pF1KE3 VFVKEDDKLIFHRHPVAQSTDAIRGKVGYTRGLHVWQITWAMRQRGTHAVVGVATADAPL
       :..:..  . .::.:.:::::. : :.:...: :.:.. :     :: ::.:.::  ::.
CCDS46 VYIKKNG-FTLHRNPIAQSTDGARTKIGFSEGRHAWEVWWEG-PLGTVAVIGIATKRAPM
             130       140       150       160        170       180

          130       140       150       160       170       180    
pF1KE3 HSVGYTTLVGNNHESWGWDLGRNRLYHDGKNQPSKTYPAFLEPDETFIVPDSFLVALDMD
       .  ::..:.:.. .::::.:  : : :.:. . :  .:   .  . . . . . : :::.
CCDS46 QCQGYVALLGSDDQSWGWNLVDNNLLHNGEVNGS--FPQCNNAPK-YQIGERIRVILDME
              190       200       210         220        230       

          190       200       210       220       230       240    
pF1KE3 DGTLSFIVDGQYMGVAFRGLKGKKLYPVVSAVWGHCEIRMRYLNGLDPEPLPLMDLCRRS
       : ::.:    ...:::::::    :::.::::.:. :. . ::                 
CCDS46 DKTLAFERGYEFLGVAFRGLPKVCLYPAVSAVYGNTEVTLVYLGKPLDG           
       240       250       260       270       280                 

          250       260       270   
pF1KE3 VRLALGRERLGEIHTLPLPASLKAYLLYQ




273 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sun Nov  6 08:25:28 2016 done: Sun Nov  6 08:25:28 2016
 Total Scan time:  2.330 Total Display time: -0.010

Function used was FASTA [36.3.4 Apr, 2011]