Result of FASTA (omim) for
pFN21AE3974
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3974, 288 aa
1>>>pF1KE3974 288 - 288 aa - 288 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.5637+/-0.000606; mu= 8.3927+/- 0.037
mean_var=179.3358+/-41.152, 0's: 0 Z-trim(112.0): 647 B-trim: 684 in 1/47
Lambda= 0.095772
statistics sampled from 20035 (20824) to 20035 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.619), E-opt: 0.2 (0.244), width: 16
Scan time: 6.130
The best scores are: opt bits E(85289)
NP_001306226 (OMIM: 615053) ankyrin repeat and SOC ( 288) 1897 275.0 1.1e-73
NP_077000 (OMIM: 615053) ankyrin repeat and SOCS b ( 288) 1897 275.0 1.1e-73
NP_001306225 (OMIM: 615053) ankyrin repeat and SOC ( 288) 1897 275.0 1.1e-73
NP_001306227 (OMIM: 615053) ankyrin repeat and SOC ( 227) 1480 217.3 2.2e-56
NP_001306228 (OMIM: 615053) ankyrin repeat and SOC ( 227) 1480 217.3 2.2e-56
NP_001306230 (OMIM: 615053) ankyrin repeat and SOC ( 85) 525 84.8 6.2e-17
NP_001306229 (OMIM: 615053) ankyrin repeat and SOC ( 85) 525 84.8 6.2e-17
XP_011531845 (OMIM: 611122) PREDICTED: serine/thre (1019) 321 57.9 9e-08
NP_078977 (OMIM: 615055) ankyrin repeat and SOCS b ( 278) 304 54.9 2e-07
XP_016861517 (OMIM: 611122) PREDICTED: serine/thre ( 687) 302 55.1 4.4e-07
XP_011531844 (OMIM: 611122) PREDICTED: serine/thre (1025) 302 55.3 5.6e-07
XP_011531843 (OMIM: 611122) PREDICTED: serine/thre (1027) 302 55.3 5.6e-07
NP_056014 (OMIM: 611122) serine/threonine-protein (1053) 302 55.3 5.7e-07
XP_005265053 (OMIM: 611122) PREDICTED: serine/thre (1083) 302 55.3 5.8e-07
XP_011531842 (OMIM: 611122) PREDICTED: serine/thre (1086) 302 55.3 5.8e-07
XP_011531848 (OMIM: 611122) PREDICTED: serine/thre ( 997) 295 54.3 1.1e-06
XP_011531847 (OMIM: 611122) PREDICTED: serine/thre ( 997) 295 54.3 1.1e-06
XP_011531849 (OMIM: 611122) PREDICTED: serine/thre ( 997) 295 54.3 1.1e-06
NP_002805 (OMIM: 300880) 26S proteasome non-ATPase ( 226) 280 51.5 1.8e-06
NP_543139 (OMIM: 615056) ankyrin repeat and SOCS b ( 453) 282 52.1 2.3e-06
NP_001162003 (OMIM: 300890) ankyrin repeat and SOC ( 262) 277 51.1 2.6e-06
NP_076992 (OMIM: 300890) ankyrin repeat and SOCS b ( 262) 277 51.1 2.6e-06
XP_005274503 (OMIM: 300890) PREDICTED: ankyrin rep ( 294) 277 51.2 2.8e-06
NP_001026909 (OMIM: 300890) ankyrin repeat and SOC ( 294) 277 51.2 2.8e-06
XP_016884775 (OMIM: 300890) PREDICTED: ankyrin rep ( 345) 277 51.3 3.1e-06
XP_016884774 (OMIM: 300890) PREDICTED: ankyrin rep ( 345) 277 51.3 3.1e-06
XP_011529919 (OMIM: 615050) PREDICTED: ankyrin rep ( 276) 275 50.9 3.3e-06
XP_016884772 (OMIM: 300890) PREDICTED: ankyrin rep ( 377) 277 51.3 3.3e-06
XP_011529918 (OMIM: 615050) PREDICTED: ankyrin rep ( 284) 275 50.9 3.3e-06
NP_543150 (OMIM: 615050) ankyrin repeat and SOCS b ( 329) 275 51.0 3.6e-06
XP_005262816 (OMIM: 615050) PREDICTED: ankyrin rep ( 329) 275 51.0 3.6e-06
NP_001139381 (OMIM: 611397) protein TANC1 isoform (1390) 279 52.3 6.1e-06
XP_011510364 (OMIM: 611397) PREDICTED: protein TAN (1554) 279 52.4 6.6e-06
XP_016860646 (OMIM: 611397) PREDICTED: protein TAN (1660) 279 52.4 6.9e-06
XP_006712877 (OMIM: 611397) PREDICTED: protein TAN (1677) 279 52.4 6.9e-06
XP_016860645 (OMIM: 611397) PREDICTED: protein TAN (1685) 279 52.4 6.9e-06
XP_011510361 (OMIM: 611397) PREDICTED: protein TAN (1697) 279 52.4 7e-06
XP_016860644 (OMIM: 611397) PREDICTED: protein TAN (1738) 279 52.4 7.1e-06
XP_011541040 (OMIM: 608774) PREDICTED: ankyrin rep ( 702) 273 51.1 7.1e-06
XP_011510360 (OMIM: 611397) PREDICTED: protein TAN (1755) 279 52.4 7.1e-06
XP_016860642 (OMIM: 611397) PREDICTED: protein TAN (1773) 279 52.4 7.2e-06
XP_016860643 (OMIM: 611397) PREDICTED: protein TAN (1773) 279 52.4 7.2e-06
XP_016860641 (OMIM: 611397) PREDICTED: protein TAN (1790) 279 52.4 7.2e-06
XP_016860640 (OMIM: 611397) PREDICTED: protein TAN (1791) 279 52.4 7.2e-06
XP_006712875 (OMIM: 611397) PREDICTED: protein TAN (1826) 279 52.5 7.3e-06
XP_016860639 (OMIM: 611397) PREDICTED: protein TAN (1838) 279 52.5 7.3e-06
XP_016860638 (OMIM: 611397) PREDICTED: protein TAN (1844) 279 52.5 7.3e-06
XP_011510357 (OMIM: 611397) PREDICTED: protein TAN (1853) 279 52.5 7.4e-06
XP_016860636 (OMIM: 611397) PREDICTED: protein TAN (1854) 279 52.5 7.4e-06
XP_016860637 (OMIM: 611397) PREDICTED: protein TAN (1854) 279 52.5 7.4e-06
>>NP_001306226 (OMIM: 615053) ankyrin repeat and SOCS bo (288 aa)
initn: 1897 init1: 1897 opt: 1897 Z-score: 1443.5 bits: 275.0 E(85289): 1.1e-73
Smith-Waterman score: 1897; 100.0% identity (100.0% similar) in 288 aa overlap (1-288:1-288)
10 20 30 40 50 60
pF1KE3 MSSSMWYIMQSIQSKYSLSERLIRTIAAIRSFPHDNVEDLIRGGADVNCTHGTLKPLHCA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSSSMWYIMQSIQSKYSLSERLIRTIAAIRSFPHDNVEDLIRGGADVNCTHGTLKPLHCA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 CMVSDADCVELLLEKGAEVNALDGYNRTALHYAAEKDEACVEVLLEYGANPNALDGNRDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CMVSDADCVELLLEKGAEVNALDGYNRTALHYAAEKDEACVEVLLEYGANPNALDGNRDT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 PLHWAAFKNNAECVRALLESGASVNALDYNNDTPLSWAAMKGNLESVSILLDYGAEVRVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PLHWAAFKNNAECVRALLESGASVNALDYNNDTPLSWAAMKGNLESVSILLDYGAEVRVI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 NLIGQTPISRLVALLVRGLGTEKEDSCFELLHRAVGHFELRKNGTMPREVARDPQLCEKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NLIGQTPISRLVALLVRGLGTEKEDSCFELLHRAVGHFELRKNGTMPREVARDPQLCEKL
190 200 210 220 230 240
250 260 270 280
pF1KE3 TVLCSAPGTLKTLARYAVRRSLGLQYLPDAVKGLPLPASLKEYLLLLE
::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TVLCSAPGTLKTLARYAVRRSLGLQYLPDAVKGLPLPASLKEYLLLLE
250 260 270 280
>>NP_077000 (OMIM: 615053) ankyrin repeat and SOCS box p (288 aa)
initn: 1897 init1: 1897 opt: 1897 Z-score: 1443.5 bits: 275.0 E(85289): 1.1e-73
Smith-Waterman score: 1897; 100.0% identity (100.0% similar) in 288 aa overlap (1-288:1-288)
10 20 30 40 50 60
pF1KE3 MSSSMWYIMQSIQSKYSLSERLIRTIAAIRSFPHDNVEDLIRGGADVNCTHGTLKPLHCA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_077 MSSSMWYIMQSIQSKYSLSERLIRTIAAIRSFPHDNVEDLIRGGADVNCTHGTLKPLHCA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 CMVSDADCVELLLEKGAEVNALDGYNRTALHYAAEKDEACVEVLLEYGANPNALDGNRDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_077 CMVSDADCVELLLEKGAEVNALDGYNRTALHYAAEKDEACVEVLLEYGANPNALDGNRDT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 PLHWAAFKNNAECVRALLESGASVNALDYNNDTPLSWAAMKGNLESVSILLDYGAEVRVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_077 PLHWAAFKNNAECVRALLESGASVNALDYNNDTPLSWAAMKGNLESVSILLDYGAEVRVI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 NLIGQTPISRLVALLVRGLGTEKEDSCFELLHRAVGHFELRKNGTMPREVARDPQLCEKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_077 NLIGQTPISRLVALLVRGLGTEKEDSCFELLHRAVGHFELRKNGTMPREVARDPQLCEKL
190 200 210 220 230 240
250 260 270 280
pF1KE3 TVLCSAPGTLKTLARYAVRRSLGLQYLPDAVKGLPLPASLKEYLLLLE
::::::::::::::::::::::::::::::::::::::::::::::::
NP_077 TVLCSAPGTLKTLARYAVRRSLGLQYLPDAVKGLPLPASLKEYLLLLE
250 260 270 280
>>NP_001306225 (OMIM: 615053) ankyrin repeat and SOCS bo (288 aa)
initn: 1897 init1: 1897 opt: 1897 Z-score: 1443.5 bits: 275.0 E(85289): 1.1e-73
Smith-Waterman score: 1897; 100.0% identity (100.0% similar) in 288 aa overlap (1-288:1-288)
10 20 30 40 50 60
pF1KE3 MSSSMWYIMQSIQSKYSLSERLIRTIAAIRSFPHDNVEDLIRGGADVNCTHGTLKPLHCA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSSSMWYIMQSIQSKYSLSERLIRTIAAIRSFPHDNVEDLIRGGADVNCTHGTLKPLHCA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 CMVSDADCVELLLEKGAEVNALDGYNRTALHYAAEKDEACVEVLLEYGANPNALDGNRDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CMVSDADCVELLLEKGAEVNALDGYNRTALHYAAEKDEACVEVLLEYGANPNALDGNRDT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 PLHWAAFKNNAECVRALLESGASVNALDYNNDTPLSWAAMKGNLESVSILLDYGAEVRVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PLHWAAFKNNAECVRALLESGASVNALDYNNDTPLSWAAMKGNLESVSILLDYGAEVRVI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 NLIGQTPISRLVALLVRGLGTEKEDSCFELLHRAVGHFELRKNGTMPREVARDPQLCEKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NLIGQTPISRLVALLVRGLGTEKEDSCFELLHRAVGHFELRKNGTMPREVARDPQLCEKL
190 200 210 220 230 240
250 260 270 280
pF1KE3 TVLCSAPGTLKTLARYAVRRSLGLQYLPDAVKGLPLPASLKEYLLLLE
::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TVLCSAPGTLKTLARYAVRRSLGLQYLPDAVKGLPLPASLKEYLLLLE
250 260 270 280
>>NP_001306227 (OMIM: 615053) ankyrin repeat and SOCS bo (227 aa)
initn: 1480 init1: 1480 opt: 1480 Z-score: 1133.3 bits: 217.3 E(85289): 2.2e-56
Smith-Waterman score: 1480; 100.0% identity (100.0% similar) in 227 aa overlap (62-288:1-227)
40 50 60 70 80 90
pF1KE3 FPHDNVEDLIRGGADVNCTHGTLKPLHCACMVSDADCVELLLEKGAEVNALDGYNRTALH
::::::::::::::::::::::::::::::
NP_001 MVSDADCVELLLEKGAEVNALDGYNRTALH
10 20 30
100 110 120 130 140 150
pF1KE3 YAAEKDEACVEVLLEYGANPNALDGNRDTPLHWAAFKNNAECVRALLESGASVNALDYNN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YAAEKDEACVEVLLEYGANPNALDGNRDTPLHWAAFKNNAECVRALLESGASVNALDYNN
40 50 60 70 80 90
160 170 180 190 200 210
pF1KE3 DTPLSWAAMKGNLESVSILLDYGAEVRVINLIGQTPISRLVALLVRGLGTEKEDSCFELL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DTPLSWAAMKGNLESVSILLDYGAEVRVINLIGQTPISRLVALLVRGLGTEKEDSCFELL
100 110 120 130 140 150
220 230 240 250 260 270
pF1KE3 HRAVGHFELRKNGTMPREVARDPQLCEKLTVLCSAPGTLKTLARYAVRRSLGLQYLPDAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HRAVGHFELRKNGTMPREVARDPQLCEKLTVLCSAPGTLKTLARYAVRRSLGLQYLPDAV
160 170 180 190 200 210
280
pF1KE3 KGLPLPASLKEYLLLLE
:::::::::::::::::
NP_001 KGLPLPASLKEYLLLLE
220
>>NP_001306228 (OMIM: 615053) ankyrin repeat and SOCS bo (227 aa)
initn: 1480 init1: 1480 opt: 1480 Z-score: 1133.3 bits: 217.3 E(85289): 2.2e-56
Smith-Waterman score: 1480; 100.0% identity (100.0% similar) in 227 aa overlap (62-288:1-227)
40 50 60 70 80 90
pF1KE3 FPHDNVEDLIRGGADVNCTHGTLKPLHCACMVSDADCVELLLEKGAEVNALDGYNRTALH
::::::::::::::::::::::::::::::
NP_001 MVSDADCVELLLEKGAEVNALDGYNRTALH
10 20 30
100 110 120 130 140 150
pF1KE3 YAAEKDEACVEVLLEYGANPNALDGNRDTPLHWAAFKNNAECVRALLESGASVNALDYNN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YAAEKDEACVEVLLEYGANPNALDGNRDTPLHWAAFKNNAECVRALLESGASVNALDYNN
40 50 60 70 80 90
160 170 180 190 200 210
pF1KE3 DTPLSWAAMKGNLESVSILLDYGAEVRVINLIGQTPISRLVALLVRGLGTEKEDSCFELL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DTPLSWAAMKGNLESVSILLDYGAEVRVINLIGQTPISRLVALLVRGLGTEKEDSCFELL
100 110 120 130 140 150
220 230 240 250 260 270
pF1KE3 HRAVGHFELRKNGTMPREVARDPQLCEKLTVLCSAPGTLKTLARYAVRRSLGLQYLPDAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HRAVGHFELRKNGTMPREVARDPQLCEKLTVLCSAPGTLKTLARYAVRRSLGLQYLPDAV
160 170 180 190 200 210
280
pF1KE3 KGLPLPASLKEYLLLLE
:::::::::::::::::
NP_001 KGLPLPASLKEYLLLLE
220
>>NP_001306230 (OMIM: 615053) ankyrin repeat and SOCS bo (85 aa)
initn: 525 init1: 525 opt: 525 Z-score: 425.0 bits: 84.8 E(85289): 6.2e-17
Smith-Waterman score: 525; 100.0% identity (100.0% similar) in 78 aa overlap (1-78:1-78)
10 20 30 40 50 60
pF1KE3 MSSSMWYIMQSIQSKYSLSERLIRTIAAIRSFPHDNVEDLIRGGADVNCTHGTLKPLHCA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSSSMWYIMQSIQSKYSLSERLIRTIAAIRSFPHDNVEDLIRGGADVNCTHGTLKPLHCA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 CMVSDADCVELLLEKGAEVNALDGYNRTALHYAAEKDEACVEVLLEYGANPNALDGNRDT
::::::::::::::::::
NP_001 CMVSDADCVELLLEKGAEDSLGVAC
70 80
>>NP_001306229 (OMIM: 615053) ankyrin repeat and SOCS bo (85 aa)
initn: 525 init1: 525 opt: 525 Z-score: 425.0 bits: 84.8 E(85289): 6.2e-17
Smith-Waterman score: 525; 100.0% identity (100.0% similar) in 78 aa overlap (1-78:1-78)
10 20 30 40 50 60
pF1KE3 MSSSMWYIMQSIQSKYSLSERLIRTIAAIRSFPHDNVEDLIRGGADVNCTHGTLKPLHCA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSSSMWYIMQSIQSKYSLSERLIRTIAAIRSFPHDNVEDLIRGGADVNCTHGTLKPLHCA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 CMVSDADCVELLLEKGAEVNALDGYNRTALHYAAEKDEACVEVLLEYGANPNALDGNRDT
::::::::::::::::::
NP_001 CMVSDADCVELLLEKGAEDSLGVAC
70 80
>>XP_011531845 (OMIM: 611122) PREDICTED: serine/threonin (1019 aa)
initn: 538 init1: 300 opt: 321 Z-score: 260.5 bits: 57.9 E(85289): 9e-08
Smith-Waterman score: 321; 37.9% identity (60.4% similar) in 169 aa overlap (21-188:41-209)
10 20 30 40 50
pF1KE3 MSSSMWYIMQSIQSKYSLSERLIRTIAAIRSFPHDNVEDLIRGGADVNCT
: . :: . :.:. :: :::
XP_011 EVEDESPAFISKLPQENKSLHSPPSGNVLVRYPSLVQAIFNGDPDEVRALIFKKEDVNFQ
20 30 40 50 60 70
60 70 80 90 100
pF1KE3 HGTLK-PLHCACMVSDADCVELLLEKGAEVNALDGYNRTALHYAAEKDEACVEVLLEYGA
. . ::: : ...::. .:::. .::.::: :. : :: :. . :..:: ::
XP_011 DNEKRTPLHAAAYLGDAEIIELLILSGARVNAKDSKWLTPLHRAVASCSEMVKLLLSRGA
80 90 100 110 120 130
110 120 130 140 150 160
pF1KE3 NPNALDGNRDTPLHWAAFKNNAECVRALLESGASVNALDYNNDTPLSWAAMKGNLESVSI
: ::.: . .::::. .. : :. :. :: :. : .. ::: :: .: . :.
XP_011 NINAFDKKDRRAIHWAAYMGHIEVVKLLVSHGAEVTCKDKKSYTPLHAAASSGMISVVKY
140 150 160 170 180 190
170 180 190 200 210 220
pF1KE3 LLDYGAEVRVINLIGQTPISRLVALLVRGLGTEKEDSCFELLHRAVGHFELRKNGTMPRE
::: :... : :.::.
XP_011 LLDLGVDMNEPNAYGNTPLHVACYNGQDVVVNELIDCGAIVNQKNEKGFTPLHFAAASTH
200 210 220 230 240 250
>--
initn: 343 init1: 167 opt: 271 Z-score: 223.1 bits: 51.0 E(85289): 1.1e-05
Smith-Waterman score: 271; 41.3% identity (65.1% similar) in 126 aa overlap (37-159:321-445)
10 20 30 40 50 60
pF1KE3 YIMQSIQSKYSLSERLIRTIAAIRSFPHDNVEDLIRGGADVNCT--HGTLKPLHCACMVS
.. :: .:::. :: . ::: : . .
XP_011 IIQSGAVIDCEDKNGNTPLHIAARYGHELLINTLITSGADTAKRGIHGMF-PLHLAALSG
300 310 320 330 340
70 80 90 100 110 120
pF1KE3 DADCVELLLEKGAEVNALDGYNRTALHYAAEKDE-ACVEVLLEYGANPNALDGNRDTPLH
.:: . :: .: .... : ..:: :: :: . :...::. ::. : : .:::
XP_011 FSDCCRKLLSSGFDIDTPDDFGRTCLHAAAAGGNLECLNLLLNTGADFNKKDKFGRSPLH
350 360 370 380 390 400
130 140 150 160 170 180
pF1KE3 WAAFKNNAECVRALLESGASVNALDYNNDTPLSWAAMKGNLESVSILLDYGAEVRVINLI
.:: . : .:. ::. :::::: :: . ::: .::
XP_011 YAAANCNYQCLFALVGSGASVNDLDERGCTPLHYAATSDTDGKCLEYLLRNDANPGIRDK
410 420 430 440 450 460
190 200 210 220 230 240
pF1KE3 GQTPISRLVALLVRGLGTEKEDSCFELLHRAVGHFELRKNGTMPREVARDPQLCEKLTVL
XP_011 QGYNAVHYSAAYGHRLCLQLIASETPLDVLMETSGTDMLSDSDNRATISPLHLAAYHGHH
470 480 490 500 510 520
>--
initn: 339 init1: 161 opt: 249 Z-score: 206.7 bits: 48.0 E(85289): 8.9e-05
Smith-Waterman score: 249; 31.7% identity (67.7% similar) in 161 aa overlap (34-188:529-689)
10 20 30 40 50 60
pF1KE3 SMWYIMQSIQSKYSLSERLIRTIAAIRSFPHDNVEDLIRGGADVNCTHGTLK-PLHCACM
:. .: :... :.. ... . :: : .
XP_011 LMETSGTDMLSDSDNRATISPLHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTPLDLAAF
500 510 520 530 540 550
70 80 90 100 110
pF1KE3 VSDADCVELLLEKGAEVNALDGY-NRTALHYAAEKDEA-CVEVLLEYGANPNALD---GN
. ..::..:...:: . . : .:: .: :: . .. :...:. . ::.: ::
XP_011 KGHVECVDVLINQGASILVKDYILKRTPIHAAATNGHSECLRLLIGNAEPQNAVDIQDGN
560 570 580 590 600 610
120 130 140 150 160 170
pF1KE3 RDTPLHWAAFKNNAECVRALLESGASVNALDYNNDTPLSWAAMKGNLESVSILLDYGAEV
.::: ........:: .::..::.:.: : . : : .:. :. : :. ::..::.
XP_011 GQTPLMLSVLNGHTDCVYSLLNKGANVDAKDKWGRTALHRGAVTGHEECVDALLQHGAKC
620 630 640 650 660 670
180 190 200 210 220 230
pF1KE3 RVINLIGQTPISRLVALLVRGLGTEKEDSCFELLHRAVGHFELRKNGTMPREVARDPQLC
. . :.:::
XP_011 LLRDSRGRTPIHLSAACGHIGVLGALLQSAASMDANPATADNHGYTALHWACYNGHETCV
680 690 700 710 720 730
>>NP_078977 (OMIM: 615055) ankyrin repeat and SOCS box p (278 aa)
initn: 388 init1: 210 opt: 304 Z-score: 254.2 bits: 54.9 E(85289): 2e-07
Smith-Waterman score: 319; 32.7% identity (58.7% similar) in 254 aa overlap (37-284:35-275)
10 20 30 40 50 60
pF1KE3 YIMQSIQSKYSLSERLIRTIAAIRSFPHDNVEDLIRGGADVN-CTHGTLKPLHCACMVSD
...::..:: :: : .. ::: : . ..
NP_078 AADGCFLGDVGFWVERTPVHEAAQRGESLQLQQLIESGACVNQVTVDSITPLHAASLQGQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 ADCVELLLEKGAEVNALDGYNRTALHYA-AEKDEACVEVLLEYGANPNALDGNRDTPLHW
: ::.::: ::.:.: . . : : : : . ::..:: :::. : .:::
NP_078 ARCVQLLLAAGAQVDARNIDGSTPLCDACASGSIECVKLLLSYGAKVNP-PLYTASPLHE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 AAFKNNAECVRALLESGASVNALDYNNDTPLSWAAMKGNLESVSILLDYGAEVRVINLIG
: .....:::: :.. ::...: : . ::: : . .:. :..::. ::.: . .:
NP_078 ACMSGSSECVRLLIDVGANLEAHDCHFGTPLHVACAREHLDCVKVLLNAGANVNAAKL-H
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 QTPISRLVALLVRGLGTEKEDSCFELLHRAVGHFELRKN-GTMPREV---ARDPQLCEKL
.: . . . . :. . .:.: . :.. : : : : . . : : .
NP_078 ETALHHAAKV--------KNVDLIEMLIEFGGNIYARDNRGKKPSDYTWSSSAPAKC--F
190 200 210 220 230
250 260 270 280
pF1KE3 TVLCSAPGTLKTLARYAVRRSLGLQYLPDAVKGLPLPASLKEYLLLLE
..: ::. : : .:.. :.. : .: : .: : .::
NP_078 EYYEKTPLTLSQLCRVNLRKATGVRGLEKIAK-LNIPPRLIDYLSYN
240 250 260 270
>>XP_016861517 (OMIM: 611122) PREDICTED: serine/threonin (687 aa)
initn: 604 init1: 192 opt: 302 Z-score: 248.2 bits: 55.1 E(85289): 4.4e-07
Smith-Waterman score: 302; 39.0% identity (64.9% similar) in 154 aa overlap (37-188:90-243)
10 20 30 40 50 60
pF1KE3 YIMQSIQSKYSLSERLIRTIAAIRSFPHDNVEDLIRGGADVNCTHGT-LKPLHCACMVSD
.: :: .:: :: . : ::: : .
XP_016 LIFKKEDVNFQDNEKRTPLHAAAYLGDAEIIELLILSGARVNAKDSKWLTPLHRAVASCS
60 70 80 90 100 110
70 80 90 100 110 120
pF1KE3 ADCVELLLEKGAEVNALDGYNRTALHYAA-EKDEACVEVLLEYGANPNALDGNRDTPLHW
. :..::...:.::: : .: :: :: .: :.:.:. .: :. : : ::
XP_016 EEAVQVLLKHSADVNARDKNWQTPLHIAAANKAVKCAEALVPLLSNVNVSDRAGRTALHH
120 130 140 150 160 170
130 140 150 160 170 180
pF1KE3 AAFKNNAECVRALLESGASVNALDYNNDTPLSWAAMKGNLESVSILLDYGAEVRVINLIG
:::....: :. :: ::..::.: .. . :::. :..: :..:...:::: . .
XP_016 AAFSGHGEMVKLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHGAEVTCKDKKS
180 190 200 210 220 230
190 200 210 220 230 240
pF1KE3 QTPISRLVALLVRGLGTEKEDSCFELLHRAVGHFELRKNGTMPREVARDPQLCEKLTVLC
::.
XP_016 YTPLHAAASSGMISVVKYLLDLGVDMNEPNAYGNTPLHVACYNGQDVVVNELIDCGAIVN
240 250 260 270 280 290
>--
initn: 167 init1: 167 opt: 271 Z-score: 225.1 bits: 50.8 E(85289): 8.5e-06
Smith-Waterman score: 271; 41.3% identity (65.1% similar) in 126 aa overlap (37-159:388-512)
10 20 30 40 50 60
pF1KE3 YIMQSIQSKYSLSERLIRTIAAIRSFPHDNVEDLIRGGADVNCT--HGTLKPLHCACMVS
.. :: .:::. :: . ::: : . .
XP_016 IIQSGAVIDCEDKNGNTPLHIAARYGHELLINTLITSGADTAKRGIHGMF-PLHLAALSG
360 370 380 390 400 410
70 80 90 100 110 120
pF1KE3 DADCVELLLEKGAEVNALDGYNRTALHYAAEKDE-ACVEVLLEYGANPNALDGNRDTPLH
.:: . :: .: .... : ..:: :: :: . :...::. ::. : : .:::
XP_016 FSDCCRKLLSSGFDIDTPDDFGRTCLHAAAAGGNLECLNLLLNTGADFNKKDKFGRSPLH
420 430 440 450 460 470
130 140 150 160 170 180
pF1KE3 WAAFKNNAECVRALLESGASVNALDYNNDTPLSWAAMKGNLESVSILLDYGAEVRVINLI
.:: . : .:. ::. :::::: :: . ::: .::
XP_016 YAAANCNYQCLFALVGSGASVNDLDERGCTPLHYAATSDTDGKCLEYLLRNDANPGIRDK
480 490 500 510 520 530
190 200 210 220 230 240
pF1KE3 GQTPISRLVALLVRGLGTEKEDSCFELLHRAVGHFELRKNGTMPREVARDPQLCEKLTVL
XP_016 QGYNAVHYSAAYGHRLCLQLIASETPLDVLMETSGTDMLSDSDNRATISPLHLAAYHGHH
540 550 560 570 580 590
288 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 08:26:33 2016 done: Sun Nov 6 08:26:34 2016
Total Scan time: 6.130 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]