Result of FASTA (ccds) for
pFN21AE3967
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3967, 404 aa
1>>>pF1KE3967 404 - 404 aa - 404 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.7745+/-0.000885; mu= 9.6136+/- 0.052
mean_var=123.1531+/-25.484, 0's: 0 Z-trim(109.5): 198 B-trim: 23 in 1/50
Lambda= 0.115572
statistics sampled from 10710 (10959) to 10710 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.708), E-opt: 0.2 (0.337), width: 16
Scan time: 2.480
The best scores are: opt bits E(32554)
CCDS9186.1 WSB2 gene_id:55884|Hs108|chr12 ( 404) 2819 481.4 6.6e-136
CCDS61252.1 WSB2 gene_id:55884|Hs108|chr12 ( 421) 2794 477.2 1.2e-134
CCDS61251.1 WSB2 gene_id:55884|Hs108|chr12 ( 194) 1313 230.0 1.4e-60
CCDS11220.1 WSB1 gene_id:26118|Hs108|chr17 ( 421) 1177 207.6 1.8e-53
CCDS11221.1 WSB1 gene_id:26118|Hs108|chr17 ( 275) 1007 179.1 4.3e-45
CCDS6981.1 WDR5 gene_id:11091|Hs108|chr9 ( 334) 358 71.0 1.9e-12
>>CCDS9186.1 WSB2 gene_id:55884|Hs108|chr12 (404 aa)
initn: 2819 init1: 2819 opt: 2819 Z-score: 2553.4 bits: 481.4 E(32554): 6.6e-136
Smith-Waterman score: 2819; 100.0% identity (100.0% similar) in 404 aa overlap (1-404:1-404)
10 20 30 40 50 60
pF1KE3 MEAGEEPLLLAELKPGRPHQFDWKSSCETWSVAFSPDGSWFAWSQGHCIVKLIPWPLEEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS91 MEAGEEPLLLAELKPGRPHQFDWKSSCETWSVAFSPDGSWFAWSQGHCIVKLIPWPLEEQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 FIPKGFEAKSRSSKNETKGRGSPKEKTLDCGQIVWGLAFSPWPSPPSRKLWARHHPQVPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS91 FIPKGFEAKSRSSKNETKGRGSPKEKTLDCGQIVWGLAFSPWPSPPSRKLWARHHPQVPD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 VSCLVLATGLNDGQIKIWEVQTGLLLLNLSGHQDVVRDLSFTPSGSLILVSASRDKTLRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS91 VSCLVLATGLNDGQIKIWEVQTGLLLLNLSGHQDVVRDLSFTPSGSLILVSASRDKTLRI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 WDLNKHGKQIQVLSGHLQWVYCCSISPDCSMLCSAAGEKSVFLWSMRSYTLIRKLEGHQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS91 WDLNKHGKQIQVLSGHLQWVYCCSISPDCSMLCSAAGEKSVFLWSMRSYTLIRKLEGHQS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 SVVSCDFSPDSALLVTASYDTNVIMWDPYTGERLRSLHHTQVDPAMDDSDVHISSLRSVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS91 SVVSCDFSPDSALLVTASYDTNVIMWDPYTGERLRSLHHTQVDPAMDDSDVHISSLRSVC
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 FSPEGLYLATVADDRLLRIWALELKTPIAFAPMTNGLCCTFFPHGGVIATGTRDGHVQFW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS91 FSPEGLYLATVADDRLLRIWALELKTPIAFAPMTNGLCCTFFPHGGVIATGTRDGHVQFW
310 320 330 340 350 360
370 380 390 400
pF1KE3 TAPRVLSSLKHLCRKALRSFLTTYQVLALPIPKKMKEFLTYRTF
::::::::::::::::::::::::::::::::::::::::::::
CCDS91 TAPRVLSSLKHLCRKALRSFLTTYQVLALPIPKKMKEFLTYRTF
370 380 390 400
>>CCDS61252.1 WSB2 gene_id:55884|Hs108|chr12 (421 aa)
initn: 2794 init1: 2794 opt: 2794 Z-score: 2530.6 bits: 477.2 E(32554): 1.2e-134
Smith-Waterman score: 2794; 99.8% identity (99.8% similar) in 402 aa overlap (3-404:20-421)
10 20 30 40
pF1KE3 MEAGEEPLLLAELKPGRPHQFDWKSSCETWSVAFSPDGSWFAW
: :::::::::::::::::::::::::::::::::::::::
CCDS61 MRVDRESRFLRGTGTGEAVAVEEPLLLAELKPGRPHQFDWKSSCETWSVAFSPDGSWFAW
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE3 SQGHCIVKLIPWPLEEQFIPKGFEAKSRSSKNETKGRGSPKEKTLDCGQIVWGLAFSPWP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS61 SQGHCIVKLIPWPLEEQFIPKGFEAKSRSSKNETKGRGSPKEKTLDCGQIVWGLAFSPWP
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE3 SPPSRKLWARHHPQVPDVSCLVLATGLNDGQIKIWEVQTGLLLLNLSGHQDVVRDLSFTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS61 SPPSRKLWARHHPQVPDVSCLVLATGLNDGQIKIWEVQTGLLLLNLSGHQDVVRDLSFTP
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE3 SGSLILVSASRDKTLRIWDLNKHGKQIQVLSGHLQWVYCCSISPDCSMLCSAAGEKSVFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS61 SGSLILVSASRDKTLRIWDLNKHGKQIQVLSGHLQWVYCCSISPDCSMLCSAAGEKSVFL
190 200 210 220 230 240
230 240 250 260 270 280
pF1KE3 WSMRSYTLIRKLEGHQSSVVSCDFSPDSALLVTASYDTNVIMWDPYTGERLRSLHHTQVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS61 WSMRSYTLIRKLEGHQSSVVSCDFSPDSALLVTASYDTNVIMWDPYTGERLRSLHHTQVD
250 260 270 280 290 300
290 300 310 320 330 340
pF1KE3 PAMDDSDVHISSLRSVCFSPEGLYLATVADDRLLRIWALELKTPIAFAPMTNGLCCTFFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS61 PAMDDSDVHISSLRSVCFSPEGLYLATVADDRLLRIWALELKTPIAFAPMTNGLCCTFFP
310 320 330 340 350 360
350 360 370 380 390 400
pF1KE3 HGGVIATGTRDGHVQFWTAPRVLSSLKHLCRKALRSFLTTYQVLALPIPKKMKEFLTYRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS61 HGGVIATGTRDGHVQFWTAPRVLSSLKHLCRKALRSFLTTYQVLALPIPKKMKEFLTYRT
370 380 390 400 410 420
pF1KE3 F
:
CCDS61 F
>>CCDS61251.1 WSB2 gene_id:55884|Hs108|chr12 (194 aa)
initn: 1313 init1: 1313 opt: 1313 Z-score: 1200.8 bits: 230.0 E(32554): 1.4e-60
Smith-Waterman score: 1313; 100.0% identity (100.0% similar) in 194 aa overlap (211-404:1-194)
190 200 210 220 230 240
pF1KE3 WDLNKHGKQIQVLSGHLQWVYCCSISPDCSMLCSAAGEKSVFLWSMRSYTLIRKLEGHQS
::::::::::::::::::::::::::::::
CCDS61 MLCSAAGEKSVFLWSMRSYTLIRKLEGHQS
10 20 30
250 260 270 280 290 300
pF1KE3 SVVSCDFSPDSALLVTASYDTNVIMWDPYTGERLRSLHHTQVDPAMDDSDVHISSLRSVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS61 SVVSCDFSPDSALLVTASYDTNVIMWDPYTGERLRSLHHTQVDPAMDDSDVHISSLRSVC
40 50 60 70 80 90
310 320 330 340 350 360
pF1KE3 FSPEGLYLATVADDRLLRIWALELKTPIAFAPMTNGLCCTFFPHGGVIATGTRDGHVQFW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS61 FSPEGLYLATVADDRLLRIWALELKTPIAFAPMTNGLCCTFFPHGGVIATGTRDGHVQFW
100 110 120 130 140 150
370 380 390 400
pF1KE3 TAPRVLSSLKHLCRKALRSFLTTYQVLALPIPKKMKEFLTYRTF
::::::::::::::::::::::::::::::::::::::::::::
CCDS61 TAPRVLSSLKHLCRKALRSFLTTYQVLALPIPKKMKEFLTYRTF
160 170 180 190
>>CCDS11220.1 WSB1 gene_id:26118|Hs108|chr17 (421 aa)
initn: 1417 init1: 714 opt: 1177 Z-score: 1073.5 bits: 207.6 E(32554): 1.8e-53
Smith-Waterman score: 1356; 51.5% identity (74.8% similar) in 400 aa overlap (13-402:23-420)
10 20 30 40 50
pF1KE3 MEAGEEPLLLAELKPGRPHQFDWKSSCETWSVAFSPDGSWFAWSQGHCIV
: :. : :: : . :.:.:::.::::.::::::: :
CCDS11 MASFPPRVNEKEIVRLRTIGELLAPAAP--FDKKCGRENWTVAFAPDGSYFAWSQGHRTV
10 20 30 40 50
60 70 80 90 100
pF1KE3 KLIPWPLEEQ-FIPKGFEAKSRSS------KNETKG-RGSPKEKTLDCGQIVWGLAF-SP
::.:: : :. .: . . :: .: : ...:.:. .:::.:::.::: :
CCDS11 KLVPWSQCLQNFLLHGTKNVTNSSSLRLPRQNSDGGQKNKPREHIIDCGDIVWSLAFGSS
60 70 80 90 100 110
110 120 130 140 150 160
pF1KE3 WPSPPSRKLWARHHPQVPDVSCLVLATGLNDGQIKIWEVQTGLLLLNLSGHQDVVRDLSF
: :: . . : . :.::::::.:.::::.: :: ::::: : .:::::.:
CCDS11 VPEKQSRCVNIEWHRFRFGQDQLLLATGLNNGRIKIWDVYTGKLLLNLVDHTEVVRDLTF
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE3 TPSGSLILVSASRDKTLRIWDLNKHGKQIQVLSGHLQWVYCCSISPDCSMLCSAAGEKSV
.:.:::::::::::::::.:::. :....:: :: .::: :..::: :::::... :.:
CCDS11 APDGSLILVSASRDKTLRVWDLKDDGNMMKVLRGHQNWVYSCAFSPDSSMLCSVGASKAV
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE3 FLWSMRSYTLIRKLEGHQSSVVSCDFSPDSALLVTASYDTNVIMWDPYTGERLRSLHHTQ
:::.: .::.:::::::. .::.::::::.:::.:::::: : .:::..:. : . :
CCDS11 FLWNMDKYTMIRKLEGHHHDVVACDFSPDGALLATASYDTRVYIWDPHNGDILMEFGHLF
240 250 260 270 280 290
290 300 310 320 330 340
pF1KE3 VDPA-MDDSDVHISSLRSVCFSPEGLYLATVADDRLLRIWALELKTPIAFAPMTNGLCCT
:. . . .. .::: :: .::..:..:::...:.: .. :. ::..:::::.
CCDS11 PPPTPIFAGGANDRWVRSVSFSHDGLHVASLADDKMVRFWRIDEDYPVQVAPLSNGLCCA
300 310 320 330 340 350
350 360 370 380 390 400
pF1KE3 FFPHGGVIATGTRDGHVQFWTAPRVLSSLKHLCRKALRSFLTTYQVLALPIPKKMKEFLT
: :.:.:.::.:: : ::..:: . ::.:::: ..: . : .: ::::.:. :::.
CCDS11 FSTDGSVLAAGTHDGSVYFWATPRQVPSLQHLCRMSIRRVMPTQEVQELPIPSKLLEFLS
360 370 380 390 400 410
pF1KE3 YRTF
::
CCDS11 YRI
420
>>CCDS11221.1 WSB1 gene_id:26118|Hs108|chr17 (275 aa)
initn: 1078 init1: 615 opt: 1007 Z-score: 923.0 bits: 179.1 E(32554): 4.3e-45
Smith-Waterman score: 1007; 53.4% identity (79.1% similar) in 268 aa overlap (136-402:7-274)
110 120 130 140 150 160
pF1KE3 PSRKLWARHHPQVPDVSCLVLATGLNDGQIKIWEVQTGLLLLNLSGHQDVVRDLSFTPSG
.. : . : ::::: : .:::::.:.:.:
CCDS11 MASFPPRVNEKEIGKLLLNLVDHTEVVRDLTFAPDG
10 20 30
170 180 190 200 210 220
pF1KE3 SLILVSASRDKTLRIWDLNKHGKQIQVLSGHLQWVYCCSISPDCSMLCSAAGEKSVFLWS
::::::::::::::.:::. :....:: :: .::: :..::: :::::... :.::::.
CCDS11 SLILVSASRDKTLRVWDLKDDGNMMKVLRGHQNWVYSCAFSPDSSMLCSVGASKAVFLWN
40 50 60 70 80 90
230 240 250 260 270 280
pF1KE3 MRSYTLIRKLEGHQSSVVSCDFSPDSALLVTASYDTNVIMWDPYTGERLRSLHHTQVDPA
: .::.:::::::. .::.::::::.:::.:::::: : .:::..:. : . : :.
CCDS11 MDKYTMIRKLEGHHHDVVACDFSPDGALLATASYDTRVYIWDPHNGDILMEFGHLFPPPT
100 110 120 130 140 150
290 300 310 320 330 340
pF1KE3 -MDDSDVHISSLRSVCFSPEGLYLATVADDRLLRIWALELKTPIAFAPMTNGLCCTFFPH
. . .. .::: :: .::..:..:::...:.: .. :. ::..:::::.:
CCDS11 PIFAGGANDRWVRSVSFSHDGLHVASLADDKMVRFWRIDEDYPVQVAPLSNGLCCAFSTD
160 170 180 190 200 210
350 360 370 380 390 400
pF1KE3 GGVIATGTRDGHVQFWTAPRVLSSLKHLCRKALRSFLTTYQVLALPIPKKMKEFLTYRTF
:.:.:.::.:: : ::..:: . ::.:::: ..: . : .: ::::.:. :::.::
CCDS11 GSVLAAGTHDGSVYFWATPRQVPSLQHLCRMSIRRVMPTQEVQELPIPSKLLEFLSYRI
220 230 240 250 260 270
>>CCDS6981.1 WDR5 gene_id:11091|Hs108|chr9 (334 aa)
initn: 356 init1: 221 opt: 358 Z-score: 336.9 bits: 71.0 E(32554): 1.9e-12
Smith-Waterman score: 424; 30.5% identity (61.0% similar) in 272 aa overlap (101-360:28-286)
80 90 100 110 120
pF1KE3 RSSKNETKGRGSPKEKTLDCGQIVWGLAFSPWPSPPSRKL---WARHHPQVPDVSCLV--
: : :. : : : : .:.
CCDS69 MATEEKKPETEAARAQPTPSSSATQSKPTPVKPNYALKFTLAGHTKAVSSVKFSPNG
10 20 30 40 50
130 140 150 160 170 180
pF1KE3 --LATGLNDGQIKIWEVQTGLLLLNLSGHQDVVRDLSFTPSGSLILVSASRDKTLRIWDL
::.. : :::: . : . ..:::. . :.... : : .::::: ::::.:::.
CCDS69 EWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWS-SDSNLLVSASDDKTLKIWDV
60 70 80 90 100 110
190 200 210 220 230 240
pF1KE3 NKHGKQIQVLSGHLQWVYCCSISPDCSMLCSAAGEKSVFLWSMRSYTLIRKLEGHQSSVV
.. :: ...:.:: ..:.::...:. ... :.. ..:: .:.... .. : .:.. :
CCDS69 SS-GKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVS
120 130 140 150 160 170
250 260 270 280 290 300
pF1KE3 SCDFSPDSALLVTASYDTNVIMWDPYTGERLRSLHHTQVDPAMDDSDVHISSLRSVCFSP
. :. :..:.:..::: .:: .:. :..: .::.. .: .. :::
CCDS69 AVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTL--------IDDDNPPVSFVK---FSP
180 190 200 210 220
310 320 330 340 350
pF1KE3 EGLYLATVADDRLLRIWAL-ELKTPIAFAPMTNGLCCTF----FPHGGVIATGTRDGHVQ
.: :. ... : :..: . : ... : : : : :..:..:. :
CCDS69 NGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVY
230 240 250 260 270 280
360 370 380 390 400
pF1KE3 FWTAPRVLSSLKHLCRKALRSFLTTYQVLALPIPKKMKEFLTYRTF
.:
CCDS69 IWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLWKSDC
290 300 310 320 330
404 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 08:29:30 2016 done: Sun Nov 6 08:29:31 2016
Total Scan time: 2.480 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]