Result of FASTA (omim) for
pFN21AE3959
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3959, 507 aa
1>>>pF1KE3959 507 - 507 aa - 507 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.9472+/-0.000334; mu= 13.5072+/- 0.021
mean_var=186.2543+/-37.829, 0's: 0 Z-trim(121.6): 9 B-trim: 97 in 1/53
Lambda= 0.093977
statistics sampled from 38370 (38380) to 38370 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.763), E-opt: 0.2 (0.45), width: 16
Scan time: 10.930
The best scores are: opt bits E(85289)
NP_005655 (OMIM: 176270,603856,615346) probable E3 ( 507) 3585 498.3 2.2e-140
NP_038474 (OMIM: 607754) E3 ubiquitin-protein liga ( 482) 1441 207.6 6.7e-53
XP_011514300 (OMIM: 607754) PREDICTED: E3 ubiquiti ( 418) 1405 202.7 1.8e-51
XP_011514299 (OMIM: 607754) PREDICTED: E3 ubiquiti ( 418) 1405 202.7 1.8e-51
XP_011514298 (OMIM: 607754) PREDICTED: E3 ubiquiti ( 439) 1405 202.7 1.8e-51
NP_001138597 (OMIM: 607754) E3 ubiquitin-protein l ( 329) 925 137.5 6e-32
NP_001258636 (OMIM: 608426) probable E3 ubiquitin- ( 373) 903 134.5 5.1e-31
NP_054879 (OMIM: 608426) probable E3 ubiquitin-pro ( 416) 900 134.2 7.3e-31
NP_001278592 (OMIM: 607754) E3 ubiquitin-protein l ( 265) 889 132.5 1.5e-30
>>NP_005655 (OMIM: 176270,603856,615346) probable E3 ubi (507 aa)
initn: 3585 init1: 3585 opt: 3585 Z-score: 2641.5 bits: 498.3 E(85289): 2.2e-140
Smith-Waterman score: 3585; 100.0% identity (100.0% similar) in 507 aa overlap (1-507:1-507)
10 20 30 40 50 60
pF1KE3 MEEPAAPSEAHEAAGAQAGAEAAREGVSGPDLPVCEPSGESAAPDSALPHAARGWAPFPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MEEPAAPSEAHEAAGAQAGAEAAREGVSGPDLPVCEPSGESAAPDSALPHAARGWAPFPV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 APVPAHLRRGGLRPAPASGGGAWPSPLPSRSSGIWTKQIICRYYIHGQCKEGENCRYSHD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 APVPAHLRRGGLRPAPASGGGAWPSPLPSRSSGIWTKQIICRYYIHGQCKEGENCRYSHD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 LSGRKMATEGGVSPPGASAGGGPSTAAHIEPPTQEVAEAPPAASSLSLPVIGSAAERGFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LSGRKMATEGGVSPPGASAGGGPSTAAHIEPPTQEVAEAPPAASSLSLPVIGSAAERGFF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 EAERDNADRGAAGGAGVESWADAIEFVPGQPYRGRWVASAPEAPLQSSETERKQMAVGSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 EAERDNADRGAAGGAGVESWADAIEFVPGQPYRGRWVASAPEAPLQSSETERKQMAVGSG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 LRFCYYASRGVCFRGESCMYLHGDICDMCGLQTLHPMDAAQREEHMRACIEAHEKDMELS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LRFCYYASRGVCFRGESCMYLHGDICDMCGLQTLHPMDAAQREEHMRACIEAHEKDMELS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 FAVQRGMDKVCGICMEVVYEKANPNDRRFGILSNCNHSFCIRCIRRWRSARQFENRIVKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 FAVQRGMDKVCGICMEVVYEKANPNDRRFGILSNCNHSFCIRCIRRWRSARQFENRIVKS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 CPQCRVTSELVIPSEFWVEEEEEKQKLIQQYKEAMSNKACRYFAEGRGNCPFGDTCFYKH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 CPQCRVTSELVIPSEFWVEEEEEKQKLIQQYKEAMSNKACRYFAEGRGNCPFGDTCFYKH
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 EYPEGWGDEPPGPGGGSFSAYWHQLVEPVRMGEGNMLYKSIKKELVVLRLASLLFKRFLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 EYPEGWGDEPPGPGGGSFSAYWHQLVEPVRMGEGNMLYKSIKKELVVLRLASLLFKRFLS
430 440 450 460 470 480
490 500
pF1KE3 LRDELPFSEDQWDLLHYELEEYFNLIL
:::::::::::::::::::::::::::
NP_005 LRDELPFSEDQWDLLHYELEEYFNLIL
490 500
>>NP_038474 (OMIM: 607754) E3 ubiquitin-protein ligase m (482 aa)
initn: 1572 init1: 1126 opt: 1441 Z-score: 1070.8 bits: 207.6 E(85289): 6.7e-53
Smith-Waterman score: 1619; 51.5% identity (71.1% similar) in 505 aa overlap (20-507:2-482)
10 20 30 40 50 60
pF1KE3 MEEPAAPSEAHEAAGAQAGAEAAREGVSGPDLPVCEPSGESAAPDSALPHAARGWAPFPV
:::: :... :: .:: .: :: . .:.:.
NP_038 MAEAATPGTTATT------SGAGAAAATA---AAASPTPIPT
10 20 30
70 80 90 100 110 120
pF1KE3 APVPAHLRRGGLRPAPASGGGAWPSPLPSRSSGIWTKQIICRYYIHGQCKEGENCRYSHD
. .:. : :: .:::. . :.: ::::. :::..:: ::::.:::::::
NP_038 VTAPS-LGAGG------GGGGS------DGSGGGWTKQVTCRYFMHGVCKEGDNCRYSHD
40 50 60 70 80
130 140 150 160 170
pF1KE3 LSGRKMATEGGVSPPGASAGGGPSTAAHIEPPTQEVAEAPP--------AASSLSLPVIG
:: ... : : : .: :: : : :.:::: ..:
NP_038 LSDSPYSVVCKYFQRGYCIYGDRCRYEHSKPLKQEEATATELTTKSSLAASSSLS-SIVG
90 100 110 120 130
180 190 200 210 220
pF1KE3 SAAERGFFEAERDNADRGAAGGAGVESWADAIEFVPGQPYRGRWVASAPEAPLQSS----
.: . ::: :.. :. ::: :.:..:::::::::: :: . : :::::.:
NP_038 PLVEMNTGEAESRNSNF-ATVGAGSEDWVNAIEFVPGQPYCGRTAPSCTEAPLQGSVTKE
140 150 160 170 180 190
230 240 250 260 270 280
pF1KE3 ETERKQMAVGSGLRFCYYASRGVCFRGESCMYLHGDICDMCGLQTLHPMDAAQREEHMRA
:.:..: :: . ..: ::. : : ::.:.::::: :::::::.::::::::: .:...
NP_038 ESEKEQTAVETKKQLCPYAAVGECRYGENCVYLHGDSCDMCGLQVLHPMDAAQRSQHIKS
200 210 220 230 240 250
290 300 310 320 330 340
pF1KE3 CIEAHEKDMELSFAVQRGMDKVCGICMEVVYEKANPNDRRFGILSNCNHSFCIRCIRRWR
:::::::::::::::::. : :::::::::::::::..:::::::::::..:..:::.::
NP_038 CIEAHEKDMELSFAVQRSKDMVCGICMEVVYEKANPSERRFGILSNCNHTYCLKCIRKWR
260 270 280 290 300 310
350 360 370 380 390 400
pF1KE3 SARQFENRIVKSCPQCRVTSELVIPSEFWVEEEEEKQKLIQQYKEAMSNKACRYFAEGRG
::.:::..:.::::.::.::..:::::.::::.::::::: .::::::::::::: ::::
NP_038 SAKQFESKIIKSCPECRITSNFVIPSEYWVEEKEEKQKLILKYKEAMSNKACRYFDEGRG
320 330 340 350 360 370
410 420 430 440 450 460
pF1KE3 NCPFGDTCFYKHEYPEGWGDEPPGPGGGSFSAYWHQ----LVEPVRMGEGNMLYKSIKKE
.:::: .::::: ::.: .:: :. : : : . : .. :.. . . ..:
NP_038 SCPFGGNCFYKHAYPDGRREEPQRQKVGTSSRYRAQRRNHFWELIEERENSNPFDNDEEE
380 390 400 410 420 430
470 480 490 500
pF1KE3 LVVLRLASLLFKRFLSL-RDELPFSEDQWDLLHYELEEYFNLIL
.:...:. .:. . . ::: :::.:::.: :::....: :
NP_038 VVTFELGEMLLMLLAAGGDDELTDSEDEWDLFHDELEDFYDLDL
440 450 460 470 480
>>XP_011514300 (OMIM: 607754) PREDICTED: E3 ubiquitin-pr (418 aa)
initn: 1343 init1: 1126 opt: 1405 Z-score: 1045.1 bits: 202.7 E(85289): 1.8e-51
Smith-Waterman score: 1511; 54.8% identity (74.0% similar) in 420 aa overlap (105-507:1-418)
80 90 100 110 120 130
pF1KE3 APASGGGAWPSPLPSRSSGIWTKQIICRYYIHGQCKEGENCRYSHDLSGRKMATEGGVSP
.:: ::::.::::::::: ...
XP_011 MHGVCKEGDNCRYSHDLSDSPYSVVCKYFQ
10 20 30
140 150 160 170 180
pF1KE3 PGASAGGGPSTAAHIEPPTQEVAEAPP--------AASSLSLPVIGSAAERGFFEAERDN
: : : .: :: : : :.:::: ..: .: . ::: :
XP_011 RGYCIYGDRCRYEHSKPLKQEEATATELTTKSSLAASSSLS-SIVGPLVEMNTGEAESRN
40 50 60 70 80
190 200 210 220 230 240
pF1KE3 ADRGAAGGAGVESWADAIEFVPGQPYRGRWVASAPEAPLQSS----ETERKQMAVGSGLR
.. :. ::: :.:..:::::::::: :: . : :::::.: :.:..: :: . .
XP_011 SNF-ATVGAGSEDWVNAIEFVPGQPYCGRTAPSCTEAPLQGSVTKEESEKEQTAVETKKQ
90 100 110 120 130 140
250 260 270 280 290 300
pF1KE3 FCYYASRGVCFRGESCMYLHGDICDMCGLQTLHPMDAAQREEHMRACIEAHEKDMELSFA
.: ::. : : ::.:.::::: :::::::.::::::::: .:...::::::::::::::
XP_011 LCPYAAVGECRYGENCVYLHGDSCDMCGLQVLHPMDAAQRSQHIKSCIEAHEKDMELSFA
150 160 170 180 190 200
310 320 330 340 350 360
pF1KE3 VQRGMDKVCGICMEVVYEKANPNDRRFGILSNCNHSFCIRCIRRWRSARQFENRIVKSCP
:::. : :::::::::::::::..:::::::::::..:..:::.::::.:::..:.::::
XP_011 VQRSKDMVCGICMEVVYEKANPSERRFGILSNCNHTYCLKCIRKWRSAKQFESKIIKSCP
210 220 230 240 250 260
370 380 390 400 410 420
pF1KE3 QCRVTSELVIPSEFWVEEEEEKQKLIQQYKEAMSNKACRYFAEGRGNCPFGDTCFYKHEY
.::.::..:::::.::::.::::::: .::::::::::::: ::::.:::: .::::: :
XP_011 ECRITSNFVIPSEYWVEEKEEKQKLILKYKEAMSNKACRYFDEGRGSCPFGGNCFYKHAY
270 280 290 300 310 320
430 440 450 460 470
pF1KE3 PEGWGDEPPGPGGGSFSAYWHQ----LVEPVRMGEGNMLYKSIKKELVVLRLASLLFKRF
:.: .:: :. : : : . : .. :.. . . ..:.:...:. .:. .
XP_011 PDGRREEPQRQKVGTSSRYRAQRRNHFWELIEERENSNPFDNDEEEVVTFELGEMLLMLL
330 340 350 360 370 380
480 490 500
pF1KE3 LSL-RDELPFSEDQWDLLHYELEEYFNLIL
. ::: :::.:::.: :::....: :
XP_011 AAGGDDELTDSEDEWDLFHDELEDFYDLDL
390 400 410
>>XP_011514299 (OMIM: 607754) PREDICTED: E3 ubiquitin-pr (418 aa)
initn: 1343 init1: 1126 opt: 1405 Z-score: 1045.1 bits: 202.7 E(85289): 1.8e-51
Smith-Waterman score: 1511; 54.8% identity (74.0% similar) in 420 aa overlap (105-507:1-418)
80 90 100 110 120 130
pF1KE3 APASGGGAWPSPLPSRSSGIWTKQIICRYYIHGQCKEGENCRYSHDLSGRKMATEGGVSP
.:: ::::.::::::::: ...
XP_011 MHGVCKEGDNCRYSHDLSDSPYSVVCKYFQ
10 20 30
140 150 160 170 180
pF1KE3 PGASAGGGPSTAAHIEPPTQEVAEAPP--------AASSLSLPVIGSAAERGFFEAERDN
: : : .: :: : : :.:::: ..: .: . ::: :
XP_011 RGYCIYGDRCRYEHSKPLKQEEATATELTTKSSLAASSSLS-SIVGPLVEMNTGEAESRN
40 50 60 70 80
190 200 210 220 230 240
pF1KE3 ADRGAAGGAGVESWADAIEFVPGQPYRGRWVASAPEAPLQSS----ETERKQMAVGSGLR
.. :. ::: :.:..:::::::::: :: . : :::::.: :.:..: :: . .
XP_011 SNF-ATVGAGSEDWVNAIEFVPGQPYCGRTAPSCTEAPLQGSVTKEESEKEQTAVETKKQ
90 100 110 120 130 140
250 260 270 280 290 300
pF1KE3 FCYYASRGVCFRGESCMYLHGDICDMCGLQTLHPMDAAQREEHMRACIEAHEKDMELSFA
.: ::. : : ::.:.::::: :::::::.::::::::: .:...::::::::::::::
XP_011 LCPYAAVGECRYGENCVYLHGDSCDMCGLQVLHPMDAAQRSQHIKSCIEAHEKDMELSFA
150 160 170 180 190 200
310 320 330 340 350 360
pF1KE3 VQRGMDKVCGICMEVVYEKANPNDRRFGILSNCNHSFCIRCIRRWRSARQFENRIVKSCP
:::. : :::::::::::::::..:::::::::::..:..:::.::::.:::..:.::::
XP_011 VQRSKDMVCGICMEVVYEKANPSERRFGILSNCNHTYCLKCIRKWRSAKQFESKIIKSCP
210 220 230 240 250 260
370 380 390 400 410 420
pF1KE3 QCRVTSELVIPSEFWVEEEEEKQKLIQQYKEAMSNKACRYFAEGRGNCPFGDTCFYKHEY
.::.::..:::::.::::.::::::: .::::::::::::: ::::.:::: .::::: :
XP_011 ECRITSNFVIPSEYWVEEKEEKQKLILKYKEAMSNKACRYFDEGRGSCPFGGNCFYKHAY
270 280 290 300 310 320
430 440 450 460 470
pF1KE3 PEGWGDEPPGPGGGSFSAYWHQ----LVEPVRMGEGNMLYKSIKKELVVLRLASLLFKRF
:.: .:: :. : : : . : .. :.. . . ..:.:...:. .:. .
XP_011 PDGRREEPQRQKVGTSSRYRAQRRNHFWELIEERENSNPFDNDEEEVVTFELGEMLLMLL
330 340 350 360 370 380
480 490 500
pF1KE3 LSL-RDELPFSEDQWDLLHYELEEYFNLIL
. ::: :::.:::.: :::....: :
XP_011 AAGGDDELTDSEDEWDLFHDELEDFYDLDL
390 400 410
>>XP_011514298 (OMIM: 607754) PREDICTED: E3 ubiquitin-pr (439 aa)
initn: 1428 init1: 1126 opt: 1405 Z-score: 1044.8 bits: 202.7 E(85289): 1.8e-51
Smith-Waterman score: 1430; 48.3% identity (69.6% similar) in 497 aa overlap (20-507:2-439)
10 20 30 40 50 60
pF1KE3 MEEPAAPSEAHEAAGAQAGAEAAREGVSGPDLPVCEPSGESAAPDSALPHAARGWAPFPV
:::: :... :: .:: .: :: . .:.:.
XP_011 MAEAATPGTTATT------SGAGAAAATA---AAASPTPIPT
10 20 30
70 80 90 100 110 120
pF1KE3 APVPAHLRRGGLRPAPASGGGAWPSPLPSRSSGIWTKQIICRYYIHGQCKEGENCRYSHD
. .:. : :: .:::. . :.: ::::. ::: :.. . : .
XP_011 VTAPS-LGAGG------GGGGS------DGSGGGWTKQVTCRYE-HSKPLKQE------E
40 50 60 70
130 140 150 160 170 180
pF1KE3 LSGRKMATEGGVSPPGASAGGGPSTAAHIEPPTQEVAEAPPAASSLSLPVIGSAAERGFF
.. ...:..... :.:::: ..: .: .
XP_011 ATATELTTKSSLA----------------------------ASSSLS-SIVGPLVEMNTG
80 90 100
190 200 210 220 230
pF1KE3 EAERDNADRGAAGGAGVESWADAIEFVPGQPYRGRWVASAPEAPLQSS----ETERKQMA
::: :.. :. ::: :.:..:::::::::: :: . : :::::.: :.:..: :
XP_011 EAESRNSNF-ATVGAGSEDWVNAIEFVPGQPYCGRTAPSCTEAPLQGSVTKEESEKEQTA
110 120 130 140 150 160
240 250 260 270 280 290
pF1KE3 VGSGLRFCYYASRGVCFRGESCMYLHGDICDMCGLQTLHPMDAAQREEHMRACIEAHEKD
: . ..: ::. : : ::.:.::::: :::::::.::::::::: .:...::::::::
XP_011 VETKKQLCPYAAVGECRYGENCVYLHGDSCDMCGLQVLHPMDAAQRSQHIKSCIEAHEKD
170 180 190 200 210 220
300 310 320 330 340 350
pF1KE3 MELSFAVQRGMDKVCGICMEVVYEKANPNDRRFGILSNCNHSFCIRCIRRWRSARQFENR
:::::::::. : :::::::::::::::..:::::::::::..:..:::.::::.:::..
XP_011 MELSFAVQRSKDMVCGICMEVVYEKANPSERRFGILSNCNHTYCLKCIRKWRSAKQFESK
230 240 250 260 270 280
360 370 380 390 400 410
pF1KE3 IVKSCPQCRVTSELVIPSEFWVEEEEEKQKLIQQYKEAMSNKACRYFAEGRGNCPFGDTC
:.::::.::.::..:::::.::::.::::::: .::::::::::::: ::::.:::: .:
XP_011 IIKSCPECRITSNFVIPSEYWVEEKEEKQKLILKYKEAMSNKACRYFDEGRGSCPFGGNC
290 300 310 320 330 340
420 430 440 450 460 470
pF1KE3 FYKHEYPEGWGDEPPGPGGGSFSAYWHQ----LVEPVRMGEGNMLYKSIKKELVVLRLAS
:::: ::.: .:: :. : : : . : .. :.. . . ..:.:...:.
XP_011 FYKHAYPDGRREEPQRQKVGTSSRYRAQRRNHFWELIEERENSNPFDNDEEEVVTFELGE
350 360 370 380 390 400
480 490 500
pF1KE3 LLFKRFLSL-RDELPFSEDQWDLLHYELEEYFNLIL
.:. . . ::: :::.:::.: :::....: :
XP_011 MLLMLLAAGGDDELTDSEDEWDLFHDELEDFYDLDL
410 420 430
>>NP_001138597 (OMIM: 607754) E3 ubiquitin-protein ligas (329 aa)
initn: 1042 init1: 687 opt: 925 Z-score: 694.6 bits: 137.5 E(85289): 6e-32
Smith-Waterman score: 1103; 51.4% identity (69.3% similar) in 352 aa overlap (20-359:2-329)
10 20 30 40 50 60
pF1KE3 MEEPAAPSEAHEAAGAQAGAEAAREGVSGPDLPVCEPSGESAAPDSALPHAARGWAPFPV
:::: :... :: .:: .: :: . .:.:.
NP_001 MAEAATPGTTATT------SGAGAAAATA---AAASPTPIPT
10 20 30
70 80 90 100 110 120
pF1KE3 APVPAHLRRGGLRPAPASGGGAWPSPLPSRSSGIWTKQIICRYYIHGQCKEGENCRYSHD
. .:. : :: .:::. . :.: ::::. :::..:: ::::.:::::::
NP_001 VTAPS-LGAGG------GGGGS------DGSGGGWTKQVTCRYFMHGVCKEGDNCRYSHD
40 50 60 70 80
130 140 150 160 170
pF1KE3 LSGRKMATEGGVSPPGASAGGGPSTAAHIEPPTQEVAEAPP--------AASSLSLPVIG
:: ... : : : .: :: : : :.:::: ..:
NP_001 LSDSPYSVVCKYFQRGYCIYGDRCRYEHSKPLKQEEATATELTTKSSLAASSSLS-SIVG
90 100 110 120 130
180 190 200 210 220
pF1KE3 SAAERGFFEAERDNADRGAAGGAGVESWADAIEFVPGQPYRGRWVASAPEAPLQSS----
.: . ::: :.. :. ::: :.:..:::::::::: :: . : :::::.:
NP_001 PLVEMNTGEAESRNSNF-ATVGAGSEDWVNAIEFVPGQPYCGRTAPSCTEAPLQGSVTKE
140 150 160 170 180 190
230 240 250 260 270 280
pF1KE3 ETERKQMAVGSGLRFCYYASRGVCFRGESCMYLHGDICDMCGLQTLHPMDAAQREEHMRA
:.:..: :: . ..: ::. : : ::.:.::::: :::::::.::::::::: .:...
NP_001 ESEKEQTAVETKKQLCPYAAVGECRYGENCVYLHGDSCDMCGLQVLHPMDAAQRSQHIKS
200 210 220 230 240 250
290 300 310 320 330 340
pF1KE3 CIEAHEKDMELSFAVQRGMDKVCGICMEVVYEKANPNDRRFGILSNCNHSFCIRCIRRWR
:::::::::::::::::. : :::::::::::::::..:::::::::::..:..:::.::
NP_001 CIEAHEKDMELSFAVQRSKDMVCGICMEVVYEKANPSERRFGILSNCNHTYCLKCIRKWR
260 270 280 290 300 310
350 360 370 380 390 400
pF1KE3 SARQFENRIVKSCPQCRVTSELVIPSEFWVEEEEEKQKLIQQYKEAMSNKACRYFAEGRG
::.:::..:.:
NP_001 SAKQFESKIIK
320
>>NP_001258636 (OMIM: 608426) probable E3 ubiquitin-prot (373 aa)
initn: 956 init1: 864 opt: 903 Z-score: 677.8 bits: 134.5 E(85289): 5.1e-31
Smith-Waterman score: 903; 41.6% identity (69.4% similar) in 320 aa overlap (121-433:1-317)
100 110 120 130 140 150
pF1KE3 SSGIWTKQIICRYYIHGQCKEGENCRYSHDLSGRKMATEGGVSPPGASAGGGPSTAAHIE
.: .... . . :.:.:::. .: ::
NP_001 MSTKQITCRYDHTRPSAAAGGAVGTMAHSV
10 20 30
160 170 180 190 200
pF1KE3 PPTQEVAEAPPAASSLSLPVIGSAAERGFFEAERDNA--DRGAAGGAGVESWADAIEFVP
: . ::. . :. : .. : : : .: . ::. .: : .. . . :
NP_001 PSPAFHSPHPPSEVTASI-VKTNSHEPGKRE-KRTLVLRDRNLSGMAERKTQPSMVS-NP
40 50 60 70 80
210 220 230 240 250 260
pF1KE3 G-----QPYRGRWVASAPEAPLQSSETERKQMAVGSGLRFCYYASRGVCFRGESCMYLHG
: :: : .: .. . . . . .. ..: ::. : : :..:.::::
NP_001 GSCSDPQPSPEMKPHSYLDAIRSGLDDVEASSSYSNEQQLCPYAAAGECRFGDACVYLHG
90 100 110 120 130 140
270 280 290 300 310 320
pF1KE3 DICDMCGLQTLHPMDAAQREEHMRACIEAHEKDMELSFAVQRGMDKVCGICMEVVYEKAN
..:..: ::.:::.: ::. : . :. . :..:: .:: : ..::::.:::::. :::.
NP_001 EVCEICRLQVLHPFDPEQRKAHEKICMLTFEHEMEKAFAFQASQDKVCSICMEVILEKAS
150 160 170 180 190 200
330 340 350 360 370 380
pF1KE3 PNDRRFGILSNCNHSFCIRCIRRWRSARQFENRIVKSCPQCRVTSELVIPSEFWVEEEEE
..:::::::::::..:. :::.:: :.:::: :.::::.::: ::.:::: .:::....
NP_001 ASERRFGILSNCNHTYCLSCIRQWRCAKQFENPIIKSCPECRVISEFVIPSVYWVEDQNK
210 220 230 240 250 260
390 400 410 420 430 440
pF1KE3 KQKLIQQYKEAMSNKACRYFAEGRGNCPFGDTCFYKHEYPEGWGDEPPGPGGGSFSAYWH
:..::. .:..:..:::.:: .:.:.::::. :.:.: ::.: :: :
NP_001 KNELIEAFKQGMGKKACKYFEQGKGTCPFGSKCLYRHAYPDGRLAEPEKPRKQLSSQGTV
270 280 290 300 310 320
450 460 470 480 490 500
pF1KE3 QLVEPVRMGEGNMLYKSIKKELVVLRLASLLFKRFLSLRDELPFSEDQWDLLHYELEEYF
NP_001 RFFNSVRLWDFIENRESRHVPNNEDVDMTELGDLFMHLSGVESSEP
330 340 350 360 370
>>NP_054879 (OMIM: 608426) probable E3 ubiquitin-protein (416 aa)
initn: 1057 init1: 864 opt: 900 Z-score: 675.1 bits: 134.2 E(85289): 7.3e-31
Smith-Waterman score: 1005; 42.1% identity (67.6% similar) in 361 aa overlap (96-433:3-360)
70 80 90 100 110 120
pF1KE3 HLRRGGLRPAPASGGGAWPSPLPSRSSGIWTKQIICRYYIHGQCKEGENCRYSHDLSGRK
:::: :::..:: :.:: .: .::::.. :
NP_054 MSTKQITCRYFMHGVCREGSQCLFSHDLANSK
10 20 30
130 140 150 160
pF1KE3 MAT-----EGGV-----------SPPGASAGGGPSTAAHIEPPTQEVAEAPPAASSLSLP
.: . : . :.:.:::. .: :: : . ::. . :.
NP_054 PSTICKYYQKGYCAYGTRCRYDHTRPSAAAGGAVGTMAHSVPSPAFHSPHPPSEVTASI-
40 50 60 70 80 90
170 180 190 200 210 220
pF1KE3 VIGSAAERGFFEAERDNA--DRGAAGGAGVESWADAIEFVPG-----QPYRGRWVASAPE
: .. : : : .: . ::. .: : .. . . :: :: : .
NP_054 VKTNSHEPGKRE-KRTLVLRDRNLSGMAERKTQPSMVS-NPGSCSDPQPSPEMKPHSYLD
100 110 120 130 140
230 240 250 260 270 280
pF1KE3 APLQSSETERKQMAVGSGLRFCYYASRGVCFRGESCMYLHGDICDMCGLQTLHPMDAAQR
: .. . . . . .. ..: ::. : : :..:.::::..:..: ::.:::.: ::
NP_054 AIRSGLDDVEASSSYSNEQQLCPYAAAGECRFGDACVYLHGEVCEICRLQVLHPFDPEQR
150 160 170 180 190 200
290 300 310 320 330 340
pF1KE3 EEHMRACIEAHEKDMELSFAVQRGMDKVCGICMEVVYEKANPNDRRFGILSNCNHSFCIR
. : . :. . :..:: .:: : ..::::.:::::. :::. ..:::::::::::..:.
NP_054 KAHEKICMLTFEHEMEKAFAFQASQDKVCSICMEVILEKASASERRFGILSNCNHTYCLS
210 220 230 240 250 260
350 360 370 380 390 400
pF1KE3 CIRRWRSARQFENRIVKSCPQCRVTSELVIPSEFWVEEEEEKQKLIQQYKEAMSNKACRY
:::.:: :.:::: :.::::.::: ::.:::: .:::....:..::. .:..:..:::.:
NP_054 CIRQWRCAKQFENPIIKSCPECRVISEFVIPSVYWVEDQNKKNELIEAFKQGMGKKACKY
270 280 290 300 310 320
410 420 430 440 450 460
pF1KE3 FAEGRGNCPFGDTCFYKHEYPEGWGDEPPGPGGGSFSAYWHQLVEPVRMGEGNMLYKSIK
: .:.:.::::. :.:.: ::.: :: :
NP_054 FEQGKGTCPFGSKCLYRHAYPDGRLAEPEKPRKQLSSQGTVRFFNSVRLWDFIENRESRH
330 340 350 360 370 380
470 480 490 500
pF1KE3 KELVVLRLASLLFKRFLSLRDELPFSEDQWDLLHYELEEYFNLIL
NP_054 VPNNEDVDMTELGDLFMHLSGVESSEP
390 400 410
>>NP_001278592 (OMIM: 607754) E3 ubiquitin-protein ligas (265 aa)
initn: 1001 init1: 687 opt: 889 Z-score: 669.3 bits: 132.5 E(85289): 1.5e-30
Smith-Waterman score: 995; 56.6% identity (73.4% similar) in 267 aa overlap (105-359:1-265)
80 90 100 110 120 130
pF1KE3 APASGGGAWPSPLPSRSSGIWTKQIICRYYIHGQCKEGENCRYSHDLSGRKMATEGGVSP
.:: ::::.::::::::: ...
NP_001 MHGVCKEGDNCRYSHDLSDSPYSVVCKYFQ
10 20 30
140 150 160 170 180
pF1KE3 PGASAGGGPSTAAHIEPPTQEVAEAPP--------AASSLSLPVIGSAAERGFFEAERDN
: : : .: :: : : :.:::: ..: .: . ::: :
NP_001 RGYCIYGDRCRYEHSKPLKQEEATATELTTKSSLAASSSLS-SIVGPLVEMNTGEAESRN
40 50 60 70 80
190 200 210 220 230 240
pF1KE3 ADRGAAGGAGVESWADAIEFVPGQPYRGRWVASAPEAPLQSS----ETERKQMAVGSGLR
.. :. ::: :.:..:::::::::: :: . : :::::.: :.:..: :: . .
NP_001 SNF-ATVGAGSEDWVNAIEFVPGQPYCGRTAPSCTEAPLQGSVTKEESEKEQTAVETKKQ
90 100 110 120 130 140
250 260 270 280 290 300
pF1KE3 FCYYASRGVCFRGESCMYLHGDICDMCGLQTLHPMDAAQREEHMRACIEAHEKDMELSFA
.: ::. : : ::.:.::::: :::::::.::::::::: .:...::::::::::::::
NP_001 LCPYAAVGECRYGENCVYLHGDSCDMCGLQVLHPMDAAQRSQHIKSCIEAHEKDMELSFA
150 160 170 180 190 200
310 320 330 340 350 360
pF1KE3 VQRGMDKVCGICMEVVYEKANPNDRRFGILSNCNHSFCIRCIRRWRSARQFENRIVKSCP
:::. : :::::::::::::::..:::::::::::..:..:::.::::.:::..:.:
NP_001 VQRSKDMVCGICMEVVYEKANPSERRFGILSNCNHTYCLKCIRKWRSAKQFESKIIK
210 220 230 240 250 260
370 380 390 400 410 420
pF1KE3 QCRVTSELVIPSEFWVEEEEEKQKLIQQYKEAMSNKACRYFAEGRGNCPFGDTCFYKHEY
507 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 08:33:19 2016 done: Sun Nov 6 08:33:20 2016
Total Scan time: 10.930 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]