Result of FASTA (ccds) for
pFN21AE3959
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3959, 507 aa
1>>>pF1KE3959 507 - 507 aa - 507 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.1893+/-0.000793; mu= 12.1026+/- 0.048
mean_var=169.3289+/-34.174, 0's: 0 Z-trim(114.4): 14 B-trim: 0 in 0/52
Lambda= 0.098562
statistics sampled from 14968 (14981) to 14968 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.777), E-opt: 0.2 (0.46), width: 16
Scan time: 3.340
The best scores are: opt bits E(32554)
CCDS10013.1 MKRN3 gene_id:7681|Hs108|chr15 ( 507) 3585 521.6 8e-148
CCDS5860.1 MKRN1 gene_id:23608|Hs108|chr7 ( 482) 1441 216.7 4.6e-56
CCDS47725.1 MKRN1 gene_id:23608|Hs108|chr7 ( 329) 925 143.2 4.3e-34
CCDS63545.1 MKRN2 gene_id:23609|Hs108|chr3 ( 373) 903 140.1 4.1e-33
CCDS33702.1 MKRN2 gene_id:23609|Hs108|chr3 ( 416) 900 139.7 5.9e-33
>>CCDS10013.1 MKRN3 gene_id:7681|Hs108|chr15 (507 aa)
initn: 3585 init1: 3585 opt: 3585 Z-score: 2767.4 bits: 521.6 E(32554): 8e-148
Smith-Waterman score: 3585; 100.0% identity (100.0% similar) in 507 aa overlap (1-507:1-507)
10 20 30 40 50 60
pF1KE3 MEEPAAPSEAHEAAGAQAGAEAAREGVSGPDLPVCEPSGESAAPDSALPHAARGWAPFPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 MEEPAAPSEAHEAAGAQAGAEAAREGVSGPDLPVCEPSGESAAPDSALPHAARGWAPFPV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 APVPAHLRRGGLRPAPASGGGAWPSPLPSRSSGIWTKQIICRYYIHGQCKEGENCRYSHD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 APVPAHLRRGGLRPAPASGGGAWPSPLPSRSSGIWTKQIICRYYIHGQCKEGENCRYSHD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 LSGRKMATEGGVSPPGASAGGGPSTAAHIEPPTQEVAEAPPAASSLSLPVIGSAAERGFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 LSGRKMATEGGVSPPGASAGGGPSTAAHIEPPTQEVAEAPPAASSLSLPVIGSAAERGFF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 EAERDNADRGAAGGAGVESWADAIEFVPGQPYRGRWVASAPEAPLQSSETERKQMAVGSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 EAERDNADRGAAGGAGVESWADAIEFVPGQPYRGRWVASAPEAPLQSSETERKQMAVGSG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 LRFCYYASRGVCFRGESCMYLHGDICDMCGLQTLHPMDAAQREEHMRACIEAHEKDMELS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 LRFCYYASRGVCFRGESCMYLHGDICDMCGLQTLHPMDAAQREEHMRACIEAHEKDMELS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 FAVQRGMDKVCGICMEVVYEKANPNDRRFGILSNCNHSFCIRCIRRWRSARQFENRIVKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 FAVQRGMDKVCGICMEVVYEKANPNDRRFGILSNCNHSFCIRCIRRWRSARQFENRIVKS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 CPQCRVTSELVIPSEFWVEEEEEKQKLIQQYKEAMSNKACRYFAEGRGNCPFGDTCFYKH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 CPQCRVTSELVIPSEFWVEEEEEKQKLIQQYKEAMSNKACRYFAEGRGNCPFGDTCFYKH
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 EYPEGWGDEPPGPGGGSFSAYWHQLVEPVRMGEGNMLYKSIKKELVVLRLASLLFKRFLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 EYPEGWGDEPPGPGGGSFSAYWHQLVEPVRMGEGNMLYKSIKKELVVLRLASLLFKRFLS
430 440 450 460 470 480
490 500
pF1KE3 LRDELPFSEDQWDLLHYELEEYFNLIL
:::::::::::::::::::::::::::
CCDS10 LRDELPFSEDQWDLLHYELEEYFNLIL
490 500
>>CCDS5860.1 MKRN1 gene_id:23608|Hs108|chr7 (482 aa)
initn: 1572 init1: 1126 opt: 1441 Z-score: 1120.0 bits: 216.7 E(32554): 4.6e-56
Smith-Waterman score: 1619; 51.5% identity (71.1% similar) in 505 aa overlap (20-507:2-482)
10 20 30 40 50 60
pF1KE3 MEEPAAPSEAHEAAGAQAGAEAAREGVSGPDLPVCEPSGESAAPDSALPHAARGWAPFPV
:::: :... :: .:: .: :: . .:.:.
CCDS58 MAEAATPGTTATT------SGAGAAAATA---AAASPTPIPT
10 20 30
70 80 90 100 110 120
pF1KE3 APVPAHLRRGGLRPAPASGGGAWPSPLPSRSSGIWTKQIICRYYIHGQCKEGENCRYSHD
. .:. : :: .:::. . :.: ::::. :::..:: ::::.:::::::
CCDS58 VTAPS-LGAGG------GGGGS------DGSGGGWTKQVTCRYFMHGVCKEGDNCRYSHD
40 50 60 70 80
130 140 150 160 170
pF1KE3 LSGRKMATEGGVSPPGASAGGGPSTAAHIEPPTQEVAEAPP--------AASSLSLPVIG
:: ... : : : .: :: : : :.:::: ..:
CCDS58 LSDSPYSVVCKYFQRGYCIYGDRCRYEHSKPLKQEEATATELTTKSSLAASSSLS-SIVG
90 100 110 120 130
180 190 200 210 220
pF1KE3 SAAERGFFEAERDNADRGAAGGAGVESWADAIEFVPGQPYRGRWVASAPEAPLQSS----
.: . ::: :.. :. ::: :.:..:::::::::: :: . : :::::.:
CCDS58 PLVEMNTGEAESRNSNF-ATVGAGSEDWVNAIEFVPGQPYCGRTAPSCTEAPLQGSVTKE
140 150 160 170 180 190
230 240 250 260 270 280
pF1KE3 ETERKQMAVGSGLRFCYYASRGVCFRGESCMYLHGDICDMCGLQTLHPMDAAQREEHMRA
:.:..: :: . ..: ::. : : ::.:.::::: :::::::.::::::::: .:...
CCDS58 ESEKEQTAVETKKQLCPYAAVGECRYGENCVYLHGDSCDMCGLQVLHPMDAAQRSQHIKS
200 210 220 230 240 250
290 300 310 320 330 340
pF1KE3 CIEAHEKDMELSFAVQRGMDKVCGICMEVVYEKANPNDRRFGILSNCNHSFCIRCIRRWR
:::::::::::::::::. : :::::::::::::::..:::::::::::..:..:::.::
CCDS58 CIEAHEKDMELSFAVQRSKDMVCGICMEVVYEKANPSERRFGILSNCNHTYCLKCIRKWR
260 270 280 290 300 310
350 360 370 380 390 400
pF1KE3 SARQFENRIVKSCPQCRVTSELVIPSEFWVEEEEEKQKLIQQYKEAMSNKACRYFAEGRG
::.:::..:.::::.::.::..:::::.::::.::::::: .::::::::::::: ::::
CCDS58 SAKQFESKIIKSCPECRITSNFVIPSEYWVEEKEEKQKLILKYKEAMSNKACRYFDEGRG
320 330 340 350 360 370
410 420 430 440 450 460
pF1KE3 NCPFGDTCFYKHEYPEGWGDEPPGPGGGSFSAYWHQ----LVEPVRMGEGNMLYKSIKKE
.:::: .::::: ::.: .:: :. : : : . : .. :.. . . ..:
CCDS58 SCPFGGNCFYKHAYPDGRREEPQRQKVGTSSRYRAQRRNHFWELIEERENSNPFDNDEEE
380 390 400 410 420 430
470 480 490 500
pF1KE3 LVVLRLASLLFKRFLSL-RDELPFSEDQWDLLHYELEEYFNLIL
.:...:. .:. . . ::: :::.:::.: :::....: :
CCDS58 VVTFELGEMLLMLLAAGGDDELTDSEDEWDLFHDELEDFYDLDL
440 450 460 470 480
>>CCDS47725.1 MKRN1 gene_id:23608|Hs108|chr7 (329 aa)
initn: 1042 init1: 687 opt: 925 Z-score: 725.6 bits: 143.2 E(32554): 4.3e-34
Smith-Waterman score: 1103; 51.4% identity (69.3% similar) in 352 aa overlap (20-359:2-329)
10 20 30 40 50 60
pF1KE3 MEEPAAPSEAHEAAGAQAGAEAAREGVSGPDLPVCEPSGESAAPDSALPHAARGWAPFPV
:::: :... :: .:: .: :: . .:.:.
CCDS47 MAEAATPGTTATT------SGAGAAAATA---AAASPTPIPT
10 20 30
70 80 90 100 110 120
pF1KE3 APVPAHLRRGGLRPAPASGGGAWPSPLPSRSSGIWTKQIICRYYIHGQCKEGENCRYSHD
. .:. : :: .:::. . :.: ::::. :::..:: ::::.:::::::
CCDS47 VTAPS-LGAGG------GGGGS------DGSGGGWTKQVTCRYFMHGVCKEGDNCRYSHD
40 50 60 70 80
130 140 150 160 170
pF1KE3 LSGRKMATEGGVSPPGASAGGGPSTAAHIEPPTQEVAEAPP--------AASSLSLPVIG
:: ... : : : .: :: : : :.:::: ..:
CCDS47 LSDSPYSVVCKYFQRGYCIYGDRCRYEHSKPLKQEEATATELTTKSSLAASSSLS-SIVG
90 100 110 120 130
180 190 200 210 220
pF1KE3 SAAERGFFEAERDNADRGAAGGAGVESWADAIEFVPGQPYRGRWVASAPEAPLQSS----
.: . ::: :.. :. ::: :.:..:::::::::: :: . : :::::.:
CCDS47 PLVEMNTGEAESRNSNF-ATVGAGSEDWVNAIEFVPGQPYCGRTAPSCTEAPLQGSVTKE
140 150 160 170 180 190
230 240 250 260 270 280
pF1KE3 ETERKQMAVGSGLRFCYYASRGVCFRGESCMYLHGDICDMCGLQTLHPMDAAQREEHMRA
:.:..: :: . ..: ::. : : ::.:.::::: :::::::.::::::::: .:...
CCDS47 ESEKEQTAVETKKQLCPYAAVGECRYGENCVYLHGDSCDMCGLQVLHPMDAAQRSQHIKS
200 210 220 230 240 250
290 300 310 320 330 340
pF1KE3 CIEAHEKDMELSFAVQRGMDKVCGICMEVVYEKANPNDRRFGILSNCNHSFCIRCIRRWR
:::::::::::::::::. : :::::::::::::::..:::::::::::..:..:::.::
CCDS47 CIEAHEKDMELSFAVQRSKDMVCGICMEVVYEKANPSERRFGILSNCNHTYCLKCIRKWR
260 270 280 290 300 310
350 360 370 380 390 400
pF1KE3 SARQFENRIVKSCPQCRVTSELVIPSEFWVEEEEEKQKLIQQYKEAMSNKACRYFAEGRG
::.:::..:.:
CCDS47 SAKQFESKIIK
320
>>CCDS63545.1 MKRN2 gene_id:23609|Hs108|chr3 (373 aa)
initn: 956 init1: 864 opt: 903 Z-score: 708.0 bits: 140.1 E(32554): 4.1e-33
Smith-Waterman score: 903; 41.6% identity (69.4% similar) in 320 aa overlap (121-433:1-317)
100 110 120 130 140 150
pF1KE3 SSGIWTKQIICRYYIHGQCKEGENCRYSHDLSGRKMATEGGVSPPGASAGGGPSTAAHIE
.: .... . . :.:.:::. .: ::
CCDS63 MSTKQITCRYDHTRPSAAAGGAVGTMAHSV
10 20 30
160 170 180 190 200
pF1KE3 PPTQEVAEAPPAASSLSLPVIGSAAERGFFEAERDNA--DRGAAGGAGVESWADAIEFVP
: . ::. . :. : .. : : : .: . ::. .: : .. . . :
CCDS63 PSPAFHSPHPPSEVTASI-VKTNSHEPGKRE-KRTLVLRDRNLSGMAERKTQPSMVS-NP
40 50 60 70 80
210 220 230 240 250 260
pF1KE3 G-----QPYRGRWVASAPEAPLQSSETERKQMAVGSGLRFCYYASRGVCFRGESCMYLHG
: :: : .: .. . . . . .. ..: ::. : : :..:.::::
CCDS63 GSCSDPQPSPEMKPHSYLDAIRSGLDDVEASSSYSNEQQLCPYAAAGECRFGDACVYLHG
90 100 110 120 130 140
270 280 290 300 310 320
pF1KE3 DICDMCGLQTLHPMDAAQREEHMRACIEAHEKDMELSFAVQRGMDKVCGICMEVVYEKAN
..:..: ::.:::.: ::. : . :. . :..:: .:: : ..::::.:::::. :::.
CCDS63 EVCEICRLQVLHPFDPEQRKAHEKICMLTFEHEMEKAFAFQASQDKVCSICMEVILEKAS
150 160 170 180 190 200
330 340 350 360 370 380
pF1KE3 PNDRRFGILSNCNHSFCIRCIRRWRSARQFENRIVKSCPQCRVTSELVIPSEFWVEEEEE
..:::::::::::..:. :::.:: :.:::: :.::::.::: ::.:::: .:::....
CCDS63 ASERRFGILSNCNHTYCLSCIRQWRCAKQFENPIIKSCPECRVISEFVIPSVYWVEDQNK
210 220 230 240 250 260
390 400 410 420 430 440
pF1KE3 KQKLIQQYKEAMSNKACRYFAEGRGNCPFGDTCFYKHEYPEGWGDEPPGPGGGSFSAYWH
:..::. .:..:..:::.:: .:.:.::::. :.:.: ::.: :: :
CCDS63 KNELIEAFKQGMGKKACKYFEQGKGTCPFGSKCLYRHAYPDGRLAEPEKPRKQLSSQGTV
270 280 290 300 310 320
450 460 470 480 490 500
pF1KE3 QLVEPVRMGEGNMLYKSIKKELVVLRLASLLFKRFLSLRDELPFSEDQWDLLHYELEEYF
CCDS63 RFFNSVRLWDFIENRESRHVPNNEDVDMTELGDLFMHLSGVESSEP
330 340 350 360 370
>>CCDS33702.1 MKRN2 gene_id:23609|Hs108|chr3 (416 aa)
initn: 1057 init1: 864 opt: 900 Z-score: 705.1 bits: 139.7 E(32554): 5.9e-33
Smith-Waterman score: 1005; 42.1% identity (67.6% similar) in 361 aa overlap (96-433:3-360)
70 80 90 100 110 120
pF1KE3 HLRRGGLRPAPASGGGAWPSPLPSRSSGIWTKQIICRYYIHGQCKEGENCRYSHDLSGRK
:::: :::..:: :.:: .: .::::.. :
CCDS33 MSTKQITCRYFMHGVCREGSQCLFSHDLANSK
10 20 30
130 140 150 160
pF1KE3 MAT-----EGGV-----------SPPGASAGGGPSTAAHIEPPTQEVAEAPPAASSLSLP
.: . : . :.:.:::. .: :: : . ::. . :.
CCDS33 PSTICKYYQKGYCAYGTRCRYDHTRPSAAAGGAVGTMAHSVPSPAFHSPHPPSEVTASI-
40 50 60 70 80 90
170 180 190 200 210 220
pF1KE3 VIGSAAERGFFEAERDNA--DRGAAGGAGVESWADAIEFVPG-----QPYRGRWVASAPE
: .. : : : .: . ::. .: : .. . . :: :: : .
CCDS33 VKTNSHEPGKRE-KRTLVLRDRNLSGMAERKTQPSMVS-NPGSCSDPQPSPEMKPHSYLD
100 110 120 130 140
230 240 250 260 270 280
pF1KE3 APLQSSETERKQMAVGSGLRFCYYASRGVCFRGESCMYLHGDICDMCGLQTLHPMDAAQR
: .. . . . . .. ..: ::. : : :..:.::::..:..: ::.:::.: ::
CCDS33 AIRSGLDDVEASSSYSNEQQLCPYAAAGECRFGDACVYLHGEVCEICRLQVLHPFDPEQR
150 160 170 180 190 200
290 300 310 320 330 340
pF1KE3 EEHMRACIEAHEKDMELSFAVQRGMDKVCGICMEVVYEKANPNDRRFGILSNCNHSFCIR
. : . :. . :..:: .:: : ..::::.:::::. :::. ..:::::::::::..:.
CCDS33 KAHEKICMLTFEHEMEKAFAFQASQDKVCSICMEVILEKASASERRFGILSNCNHTYCLS
210 220 230 240 250 260
350 360 370 380 390 400
pF1KE3 CIRRWRSARQFENRIVKSCPQCRVTSELVIPSEFWVEEEEEKQKLIQQYKEAMSNKACRY
:::.:: :.:::: :.::::.::: ::.:::: .:::....:..::. .:..:..:::.:
CCDS33 CIRQWRCAKQFENPIIKSCPECRVISEFVIPSVYWVEDQNKKNELIEAFKQGMGKKACKY
270 280 290 300 310 320
410 420 430 440 450 460
pF1KE3 FAEGRGNCPFGDTCFYKHEYPEGWGDEPPGPGGGSFSAYWHQLVEPVRMGEGNMLYKSIK
: .:.:.::::. :.:.: ::.: :: :
CCDS33 FEQGKGTCPFGSKCLYRHAYPDGRLAEPEKPRKQLSSQGTVRFFNSVRLWDFIENRESRH
330 340 350 360 370 380
470 480 490 500
pF1KE3 KELVVLRLASLLFKRFLSLRDELPFSEDQWDLLHYELEEYFNLIL
CCDS33 VPNNEDVDMTELGDLFMHLSGVESSEP
390 400 410
507 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 08:33:18 2016 done: Sun Nov 6 08:33:19 2016
Total Scan time: 3.340 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]