Result of FASTA (omim) for
pFN21AE3955
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3955, 755 aa
1>>>pF1KE3955 755 - 755 aa - 755 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.6122+/-0.000398; mu= 11.4143+/- 0.025
mean_var=224.1439+/-46.743, 0's: 0 Z-trim(119.3): 119 B-trim: 147 in 2/52
Lambda= 0.085666
statistics sampled from 33097 (33248) to 33097 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.734), E-opt: 0.2 (0.39), width: 16
Scan time: 13.430
The best scores are: opt bits E(85289)
XP_011514891 (OMIM: 616996) PREDICTED: E3 ubiquiti ( 755) 5161 651.5 3.6e-186
NP_112223 (OMIM: 616996) E3 ubiquitin-protein liga ( 755) 5161 651.5 3.6e-186
XP_011540501 (OMIM: 609318) PREDICTED: tripartite ( 476) 357 57.6 1.4e-07
NP_079464 (OMIM: 609318) tripartite motif-containi ( 580) 357 57.7 1.6e-07
NP_001139107 (OMIM: 609318) tripartite motif-conta ( 562) 349 56.7 3.2e-07
NP_005753 (OMIM: 601742) transcription intermediar ( 835) 336 55.2 1.3e-06
XP_016872587 (OMIM: 605493) PREDICTED: tripartite ( 744) 329 54.3 2.1e-06
NP_006449 (OMIM: 605493) tripartite motif-containi ( 744) 329 54.3 2.1e-06
NP_001234935 (OMIM: 605493) tripartite motif-conta ( 744) 329 54.3 2.1e-06
XP_011518146 (OMIM: 605493) PREDICTED: tripartite ( 744) 329 54.3 2.1e-06
NP_150594 (OMIM: 605493) tripartite motif-containi ( 744) 329 54.3 2.1e-06
XP_016856943 (OMIM: 188550,605769) PREDICTED: E3 u ( 638) 324 53.6 3e-06
NP_148980 (OMIM: 188550,605769) E3 ubiquitin-prote (1110) 324 53.9 4.2e-06
NP_056990 (OMIM: 188550,605769) E3 ubiquitin-prote (1127) 324 53.9 4.3e-06
XP_005270994 (OMIM: 188550,605769) PREDICTED: E3 u (1134) 324 53.9 4.3e-06
XP_011539870 (OMIM: 188550,605769) PREDICTED: E3 u (1150) 324 53.9 4.3e-06
XP_005270993 (OMIM: 188550,605769) PREDICTED: E3 u (1151) 324 53.9 4.3e-06
XP_016863439 (OMIM: 614141,615490) PREDICTED: trip ( 744) 304 51.2 1.8e-05
XP_016863438 (OMIM: 614141,615490) PREDICTED: trip ( 744) 304 51.2 1.8e-05
XP_016863437 (OMIM: 614141,615490) PREDICTED: trip ( 744) 304 51.2 1.8e-05
NP_001123539 (OMIM: 614141,615490) tripartite moti ( 744) 304 51.2 1.8e-05
XP_016863434 (OMIM: 614141,615490) PREDICTED: trip ( 744) 304 51.2 1.8e-05
XP_016863433 (OMIM: 614141,615490) PREDICTED: trip ( 744) 304 51.2 1.8e-05
XP_016863441 (OMIM: 614141,615490) PREDICTED: trip ( 744) 304 51.2 1.8e-05
XP_016863440 (OMIM: 614141,615490) PREDICTED: trip ( 744) 304 51.2 1.8e-05
XP_016863436 (OMIM: 614141,615490) PREDICTED: trip ( 761) 304 51.2 1.8e-05
XP_016863435 (OMIM: 614141,615490) PREDICTED: trip ( 762) 304 51.2 1.8e-05
XP_016863432 (OMIM: 614141,615490) PREDICTED: trip ( 770) 304 51.2 1.9e-05
NP_056086 (OMIM: 614141,615490) tripartite motif-c ( 771) 304 51.2 1.9e-05
XP_011530098 (OMIM: 614141,615490) PREDICTED: trip ( 748) 299 50.6 2.8e-05
XP_011530097 (OMIM: 614141,615490) PREDICTED: trip ( 748) 299 50.6 2.8e-05
XP_006714224 (OMIM: 614141,615490) PREDICTED: trip ( 748) 299 50.6 2.8e-05
XP_006714225 (OMIM: 614141,615490) PREDICTED: trip ( 748) 299 50.6 2.8e-05
XP_011530100 (OMIM: 614141,615490) PREDICTED: trip ( 748) 299 50.6 2.8e-05
XP_006714223 (OMIM: 614141,615490) PREDICTED: trip ( 748) 299 50.6 2.8e-05
XP_011530096 (OMIM: 614141,615490) PREDICTED: trip ( 765) 299 50.6 2.8e-05
XP_006714222 (OMIM: 614141,615490) PREDICTED: trip ( 766) 299 50.6 2.8e-05
XP_006714221 (OMIM: 614141,615490) PREDICTED: trip ( 774) 299 50.6 2.9e-05
XP_006714220 (OMIM: 614141,615490) PREDICTED: trip ( 775) 299 50.6 2.9e-05
NP_001289623 (OMIM: 614141,615490) tripartite moti ( 154) 285 48.1 3.3e-05
NP_001289622 (OMIM: 614141,615490) tripartite moti ( 162) 285 48.1 3.4e-05
NP_001289621 (OMIM: 614141,615490) tripartite moti ( 163) 285 48.1 3.4e-05
NP_001234936 (OMIM: 605493) tripartite motif-conta ( 625) 289 49.3 5.8e-05
XP_011518147 (OMIM: 605493) PREDICTED: tripartite ( 625) 289 49.3 5.8e-05
XP_016872588 (OMIM: 605493) PREDICTED: tripartite ( 625) 289 49.3 5.8e-05
XP_016863444 (OMIM: 614141,615490) PREDICTED: trip ( 619) 264 46.2 0.00049
XP_016863443 (OMIM: 614141,615490) PREDICTED: trip ( 619) 264 46.2 0.00049
NP_150231 (OMIM: 601747) E3 ubiquitin-protein liga ( 546) 262 45.9 0.00054
XP_016864933 (OMIM: 601747) PREDICTED: E3 ubiquiti ( 569) 262 45.9 0.00056
NP_150230 (OMIM: 601747) E3 ubiquitin-protein liga ( 569) 262 45.9 0.00056
>>XP_011514891 (OMIM: 616996) PREDICTED: E3 ubiquitin-pr (755 aa)
initn: 5161 init1: 5161 opt: 5161 Z-score: 3463.3 bits: 651.5 E(85289): 3.6e-186
Smith-Waterman score: 5161; 100.0% identity (100.0% similar) in 755 aa overlap (1-755:1-755)
10 20 30 40 50 60
pF1KE3 MVSHGSSPSLLEALSSDFLACKICLEQLRAPKTLPCLHTYCQDCLAQLADGGRVRCPECR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MVSHGSSPSLLEALSSDFLACKICLEQLRAPKTLPCLHTYCQDCLAQLADGGRVRCPECR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 ETVPVPPEGVASFKTNFFVNGLLDLVKARACGDLRAGKPACALCPLVGGTSTGGPATARC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ETVPVPPEGVASFKTNFFVNGLLDLVKARACGDLRAGKPACALCPLVGGTSTGGPATARC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 LDCADDLCQACADGHRCTRQTHTHRVVDLVGYRAGWYDEEARERQAAQCPQHPGEALRFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LDCADDLCQACADGHRCTRQTHTHRVVDLVGYRAGWYDEEARERQAAQCPQHPGEALRFL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 CQPCSQLLCRECRLDPHLDHPCLPLAEAVRARRPGLEGLLAGVDNNLVELEAARRVEKEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CQPCSQLLCRECRLDPHLDHPCLPLAEAVRARRPGLEGLLAGVDNNLVELEAARRVEKEA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 LARLREQAARVGTQVEEAAEGVLRALLAQKQEVLGQLRAHVEAAEEAARERLAELEGREQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LARLREQAARVGTQVEEAAEGVLRALLAQKQEVLGQLRAHVEAAEEAARERLAELEGREQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 VARAAAAFARRVLSLGREAEILSLEGAIAQRLRQLQGCPWAPGPAPCLLPQLELHPGLLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VARAAAAFARRVLSLGREAEILSLEGAIAQRLRQLQGCPWAPGPAPCLLPQLELHPGLLD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 KNCHLLRLSFEEQQPQKDGGKDGAGTQGGEESQSRREDEPKTERQGGVQPQAGDGAQTPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KNCHLLRLSFEEQQPQKDGGKDGAGTQGGEESQSRREDEPKTERQGGVQPQAGDGAQTPK
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 EEKAQTTREEGAQTLEEDRAQTPHEDGGPQPHRGGRPNKKKKFKGRLKSISREPSPALGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEKAQTTREEGAQTLEEDRAQTPHEDGGPQPHRGGRPNKKKKFKGRLKSISREPSPALGP
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 NLDGSGLLPRPIFYCSFPTRMPGDKRSPRITGLCPFGPREILVADEQNRALKRFSLNGDY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NLDGSGLLPRPIFYCSFPTRMPGDKRSPRITGLCPFGPREILVADEQNRALKRFSLNGDY
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 KGTVPVPEGCSPCSVAALQSAVAFSASARLYLINPNGEVQWRRALSLSQASHAVAALPSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KGTVPVPEGCSPCSVAALQSAVAFSASARLYLINPNGEVQWRRALSLSQASHAVAALPSG
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 DRVAVSVAGHVEVYNMEGSLATRFIPGGKASRGLRALVFLTTSPQGHFVGSDWQQNSVVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DRVAVSVAGHVEVYNMEGSLATRFIPGGKASRGLRALVFLTTSPQGHFVGSDWQQNSVVI
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 CDGLGQVVGEYKGPGLHGCQPGSVSVDKKGYIFLTLREVNKVVILDPKGSLLGDFLTAYH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CDGLGQVVGEYKGPGLHGCQPGSVSVDKKGYIFLTLREVNKVVILDPKGSLLGDFLTAYH
670 680 690 700 710 720
730 740 750
pF1KE3 GLEKPRVTTMVDGRYLVVSLSNGTIHIFRVRSPDS
:::::::::::::::::::::::::::::::::::
XP_011 GLEKPRVTTMVDGRYLVVSLSNGTIHIFRVRSPDS
730 740 750
>>NP_112223 (OMIM: 616996) E3 ubiquitin-protein ligase T (755 aa)
initn: 5161 init1: 5161 opt: 5161 Z-score: 3463.3 bits: 651.5 E(85289): 3.6e-186
Smith-Waterman score: 5161; 100.0% identity (100.0% similar) in 755 aa overlap (1-755:1-755)
10 20 30 40 50 60
pF1KE3 MVSHGSSPSLLEALSSDFLACKICLEQLRAPKTLPCLHTYCQDCLAQLADGGRVRCPECR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_112 MVSHGSSPSLLEALSSDFLACKICLEQLRAPKTLPCLHTYCQDCLAQLADGGRVRCPECR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 ETVPVPPEGVASFKTNFFVNGLLDLVKARACGDLRAGKPACALCPLVGGTSTGGPATARC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_112 ETVPVPPEGVASFKTNFFVNGLLDLVKARACGDLRAGKPACALCPLVGGTSTGGPATARC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 LDCADDLCQACADGHRCTRQTHTHRVVDLVGYRAGWYDEEARERQAAQCPQHPGEALRFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_112 LDCADDLCQACADGHRCTRQTHTHRVVDLVGYRAGWYDEEARERQAAQCPQHPGEALRFL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 CQPCSQLLCRECRLDPHLDHPCLPLAEAVRARRPGLEGLLAGVDNNLVELEAARRVEKEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_112 CQPCSQLLCRECRLDPHLDHPCLPLAEAVRARRPGLEGLLAGVDNNLVELEAARRVEKEA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 LARLREQAARVGTQVEEAAEGVLRALLAQKQEVLGQLRAHVEAAEEAARERLAELEGREQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_112 LARLREQAARVGTQVEEAAEGVLRALLAQKQEVLGQLRAHVEAAEEAARERLAELEGREQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 VARAAAAFARRVLSLGREAEILSLEGAIAQRLRQLQGCPWAPGPAPCLLPQLELHPGLLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_112 VARAAAAFARRVLSLGREAEILSLEGAIAQRLRQLQGCPWAPGPAPCLLPQLELHPGLLD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 KNCHLLRLSFEEQQPQKDGGKDGAGTQGGEESQSRREDEPKTERQGGVQPQAGDGAQTPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_112 KNCHLLRLSFEEQQPQKDGGKDGAGTQGGEESQSRREDEPKTERQGGVQPQAGDGAQTPK
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 EEKAQTTREEGAQTLEEDRAQTPHEDGGPQPHRGGRPNKKKKFKGRLKSISREPSPALGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_112 EEKAQTTREEGAQTLEEDRAQTPHEDGGPQPHRGGRPNKKKKFKGRLKSISREPSPALGP
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 NLDGSGLLPRPIFYCSFPTRMPGDKRSPRITGLCPFGPREILVADEQNRALKRFSLNGDY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_112 NLDGSGLLPRPIFYCSFPTRMPGDKRSPRITGLCPFGPREILVADEQNRALKRFSLNGDY
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 KGTVPVPEGCSPCSVAALQSAVAFSASARLYLINPNGEVQWRRALSLSQASHAVAALPSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_112 KGTVPVPEGCSPCSVAALQSAVAFSASARLYLINPNGEVQWRRALSLSQASHAVAALPSG
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 DRVAVSVAGHVEVYNMEGSLATRFIPGGKASRGLRALVFLTTSPQGHFVGSDWQQNSVVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_112 DRVAVSVAGHVEVYNMEGSLATRFIPGGKASRGLRALVFLTTSPQGHFVGSDWQQNSVVI
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 CDGLGQVVGEYKGPGLHGCQPGSVSVDKKGYIFLTLREVNKVVILDPKGSLLGDFLTAYH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_112 CDGLGQVVGEYKGPGLHGCQPGSVSVDKKGYIFLTLREVNKVVILDPKGSLLGDFLTAYH
670 680 690 700 710 720
730 740 750
pF1KE3 GLEKPRVTTMVDGRYLVVSLSNGTIHIFRVRSPDS
:::::::::::::::::::::::::::::::::::
NP_112 GLEKPRVTTMVDGRYLVVSLSNGTIHIFRVRSPDS
730 740 750
>>XP_011540501 (OMIM: 609318) PREDICTED: tripartite moti (476 aa)
initn: 404 init1: 255 opt: 357 Z-score: 256.8 bits: 57.6 E(85289): 1.4e-07
Smith-Waterman score: 357; 24.1% identity (58.2% similar) in 316 aa overlap (119-428:42-350)
90 100 110 120 130 140
pF1KE3 RACGDLRAGKPACALCPLVGGTSTGGPATARCLDCADDLCQACADGHRCTRQTHTHRVVD
:: : .::. : ..:: ..: : .::
XP_011 LAVNDVMLESLRGEGQGLVCDLCNDREVEKRCQTCKANLCHFCCQAHRRQKKTTYHTMVD
20 30 40 50 60 70
150 160 170 180 190 200
pF1KE3 LVGYRAGWYDEEARERQAAQCPQHPGEALRFLCQPCSQLLCRECRLDPHLDHPCLPLAEA
: . :. .: . :: ::.: ::..:. :.. .:..: . : .::: ...
XP_011 LKDLK-GY----SRIGKPILCPVHPAEELRLFCEFCDRPVCQDCVVGEHREHPCDFTSNV
80 90 100 110 120
210 220 230 240 250 260
pF1KE3 VRARRPGLEGLLAGVDNNLVELEAARRVEKEALARLREQAARVGTQVEEAAEGVLRALLA
.. . .. :: :.. .. :: : . . :.... :...:. .:: ..:.
XP_011 IHKHGDSVWELLKGTQPHVEALEEALAQIHIINSALQKRVEAVAADVRTFSEGYIKAIEE
130 140 150 160 170 180
270 280 290 300 310 320
pF1KE3 QKQEVLGQLRAHVEAAEEAARERLAELEGREQVARAAAAFARRVLSLGREAEILSLEGAI
.....: ::. :.. . . :.:: :... :....:. : . ::: . ..
XP_011 HRDKLLKQLEDIRAQKENSLQLQKAQLEQLLADMRTGVEFTEHLLTSGSDLEILITKRVV
190 200 210 220 230 240
330 340 350 360 370 380
pF1KE3 AQRLRQLQGCPWAPGPAPCLLPQLELHPGLLDKNCHLLRLSFEEQQPQKDGGK---DGAG
..:::.:. .. :. . .... : .:. .. . . : .: .:
XP_011 VERLRKLNKVQYSTRPG--VNDKIRFCPQEKAGQCRGYEIYGTINTKEVDPAKCVLQGED
250 260 270 280 290 300
390 400 410 420 430 440
pF1KE3 TQGGEESQSRREDEPKTERQGGVQPQAGDGAQT---PKEEKAQTTREEGAQTLEEDRAQT
. ..:.:. . : .. ..::..:. ::..: . .:
XP_011 LHRAREKQTASFTLLCKDAAGEIMGRGGDNVQVAVVPKDKKDSPVRTMVQDNKDGTYYIS
310 320 330 340 350 360
450 460 470 480 490 500
pF1KE3 PHEDGGPQPHRGGRPNKKKKFKGRLKSISREPSPALGPNLDGSGLLPRPIFYCSFPTRMP
XP_011 YTPKEPGVYTVWVCIKEQHVQGSPFTVMVRRKHRPHSGVFHCCTFCSSGGQKTARCACGG
370 380 390 400 410 420
>>NP_079464 (OMIM: 609318) tripartite motif-containing p (580 aa)
initn: 492 init1: 255 opt: 357 Z-score: 255.8 bits: 57.7 E(85289): 1.6e-07
Smith-Waterman score: 455; 24.7% identity (53.0% similar) in 445 aa overlap (21-428:29-454)
10 20 30 40 50
pF1KE3 MVSHGSSPSLLEALSSDFLACKICLEQLRAPKTLPCLHTYCQDCLAQLAD--
: .:: ..::. :::::: : :: ::
NP_079 MSENRKPLLGFVSKLTSGTALGNSGKTHCPLCLGLFKAPRLLPCLHTVCTTCLEQLEPFS
10 20 30 40 50 60
60 70 80
pF1KE3 -----GGR-----------------------VRCPECRETVPVPPEGVASFKTNFF-VNG
:: . :: : : .: :: .. . . ::
NP_079 VVDIRGGDSDTSSEGSIFQELKPRSLQSQIGILCPVCDAQVDLPMGGVKALTIDHLAVND
70 80 90 100 110 120
90 100 110 120 130 140
pF1KE3 LLDLVKARACGDLRAGKPACALCPLVGGTSTGGPATARCLDCADDLCQACADGHRCTRQT
.. : . :. :. : .: :: . . :: : .::. : ..:: ..:
NP_079 VM-LESLRGEGQ---GL-VCDLC-------NDREVEKRCQTCKANLCHFCCQAHRRQKKT
130 140 150 160
150 160 170 180 190 200
pF1KE3 HTHRVVDLVGYRAGWYDEEARERQAAQCPQHPGEALRFLCQPCSQLLCRECRLDPHLDHP
: .::: . :. .: . :: ::.: ::..:. :.. .:..: . : .::
NP_079 TYHTMVDLKDLK-GY----SRIGKPILCPVHPAEELRLFCEFCDRPVCQDCVVGEHREHP
170 180 190 200 210 220
210 220 230 240 250 260
pF1KE3 CLPLAEAVRARRPGLEGLLAGVDNNLVELEAARRVEKEALARLREQAARVGTQVEEAAEG
: ..... . .. :: :.. .. :: : . . :.... :...:. .::
NP_079 CDFTSNVIHKHGDSVWELLKGTQPHVEALEEALAQIHIINSALQKRVEAVAADVRTFSEG
230 240 250 260 270 280
270 280 290 300 310 320
pF1KE3 VLRALLAQKQEVLGQLRAHVEAAEEAARERLAELEGREQVARAAAAFARRVLSLGREAEI
..:. .....: ::. :.. . . :.:: :... :....:. : . ::
NP_079 YIKAIEEHRDKLLKQLEDIRAQKENSLQLQKAQLEQLLADMRTGVEFTEHLLTSGSDLEI
290 300 310 320 330 340
330 340 350 360 370 380
pF1KE3 LSLEGAIAQRLRQLQGCPWAPGPAPCLLPQLELHPGLLDKNCHLLRLSFEEQQPQKDGGK
: . ....:::.:. .. :. . .... : .:. .. . . : .:
NP_079 LITKRVVVERLRKLNKVQYSTRPG--VNDKIRFCPQEKAGQCRGYEIYGTINTKEVDPAK
350 360 370 380 390 400
390 400 410 420 430
pF1KE3 ---DGAGTQGGEESQSRREDEPKTERQGGVQPQAGDGAQT---PKEEKAQTTREEGAQTL
.: . ..:.:. . : .. ..::..:. ::..: . .:
NP_079 CVLQGEDLHRAREKQTASFTLLCKDAAGEIMGRGGDNVQVAVVPKDKKDSPVRTMVQDNK
410 420 430 440 450 460
440 450 460 470 480 490
pF1KE3 EEDRAQTPHEDGGPQPHRGGRPNKKKKFKGRLKSISREPSPALGPNLDGSGLLPRPIFYC
NP_079 DGTYYISYTPKEPGVYTVWVCIKEQHVQGSPFTVMVRRKHRPHSGVFHCCTFCSSGGQKT
470 480 490 500 510 520
>>NP_001139107 (OMIM: 609318) tripartite motif-containin (562 aa)
initn: 470 init1: 260 opt: 349 Z-score: 250.6 bits: 56.7 E(85289): 3.2e-07
Smith-Waterman score: 451; 25.6% identity (52.0% similar) in 442 aa overlap (21-428:29-436)
10 20 30 40 50
pF1KE3 MVSHGSSPSLLEALSSDFLACKICLEQLRAPKTLPCLHTYCQDCLAQLAD--
: .:: ..::. :::::: : :: ::
NP_001 MSENRKPLLGFVSKLTSGTALGNSGKTHCPLCLGLFKAPRLLPCLHTVCTTCLEQLEPFS
10 20 30 40 50 60
60 70 80
pF1KE3 -----GGR-----------------------VRCPECRETVPVPPEGVASFKTNFF-VNG
:: . :: : : .: :: .. . . ::
NP_001 VVDIRGGDSDTSSEGSIFQELKPRSLQSQIGILCPVCDAQVDLPMGGVKALTIDHLAVND
70 80 90 100 110 120
90 100 110 120 130 140
pF1KE3 LLDLVKARACGDLRAGKPACALCPLVGGTSTGGPATARCLDCADDLCQACADGHRCTRQT
.. : . :. :. : .: :: . . :: : .::. : ..:: ..:
NP_001 VM-LESLRGEGQ---GL-VCDLC-------NDREVEKRCQTCKANLCHFCCQAHRRQKKT
130 140 150 160
150 160 170 180 190 200
pF1KE3 HTHRVVDLVGYRAGWYDEEARERQAAQCPQHPGEALRFLCQPCSQLLCRECRLDPHLDHP
: .::: . :. .: . :: ::.: ::..:. :.. .:..: . : .::
NP_001 TYHTMVDLKDLK-GY----SRIGKPILCPVHPAEELRLFCEFCDRPVCQDCVVGEHREHP
170 180 190 200 210 220
210 220 230 240 250 260
pF1KE3 CLPLAEAVRARRPGLEGLLAGVDNNLVELEAARRVEKEALARLREQAARVGTQVEEAAEG
: ..... . .. :: :.. .. :: : . . :.... :...:. .::
NP_001 CDFTSNVIHKHGDSVWELLKGTQPHVEALEEALAQIHIINSALQKRVEAVAADVRTFSEG
230 240 250 260 270 280
270 280 290 300 310 320
pF1KE3 VLRALLAQKQEVLGQLRAHVEAAEEAARERLAELEGREQVARAAAAFARRVLSLGREAEI
..:. .....: ::. :.. . . :.:: :... :....:. : . ::
NP_001 YIKAIEEHRDKLLKQLEDIRAQKENSLQLQKAQLEQLLADMRTGVEFTEHLLTSGSDLEI
290 300 310 320 330 340
330 340 350 360 370 380
pF1KE3 LSLEGAIAQRLRQLQGCPWAPGPAPCLLPQLELHPGLLDKNCHLLRLSFEEQQPQKDGGK
: . ....:::.:. : .::. :: .:. .:. : :
NP_001 LITKRVVVERLRKLNKV------------QYSTRPGVNDK----IRFCPQEKAGQCRG-Y
350 360 370 380
390 400 410 420 430
pF1KE3 DGAGTQGGEESQSRREDEPKTERQGGVQPQAGDGAQT---PKEEKAQTTREEGAQTLEED
. . ..:.:. . : .. ..::..:. ::..: . .:
NP_001 EIYDLHRAREKQTASFTLLCKDAAGEIMGRGGDNVQVAVVPKDKKDSPVRTMVQDNKDGT
390 400 410 420 430 440
440 450 460 470 480 490
pF1KE3 RAQTPHEDGGPQPHRGGRPNKKKKFKGRLKSISREPSPALGPNLDGSGLLPRPIFYCSFP
NP_001 YYISYTPKEPGVYTVWVCIKEQHVQGSPFTVMVRRKHRPHSGVFHCCTFCSSGGQKTARC
450 460 470 480 490 500
>>NP_005753 (OMIM: 601742) transcription intermediary fa (835 aa)
initn: 207 init1: 109 opt: 336 Z-score: 239.9 bits: 55.2 E(85289): 1.3e-06
Smith-Waterman score: 374; 26.6% identity (53.1% similar) in 305 aa overlap (6-292:49-328)
10 20 30
pF1KE3 MVSHGSSPSLLEALSSDFLA-CKICLEQLRA---P
:::. : . ..: : .: :.:: :
NP_005 SPGPGEGSAGGEKRSTAPSAAASASASAAASSPAGGGAEALELLEHCGVCRERLRPEREP
20 30 40 50 60 70
40 50 60 70
pF1KE3 KTLPCLHTYCQDCLAQLA--------DGGR------VRCPECRETVPVPPEGVASFKTNF
. :::::. :. ::. : ::: : :: :.. :. ..
NP_005 RLLPCLHSACSACLGPAAPAAANSSGDGGAAGDGTVVDCPVCKQQC---------FSKDI
80 90 100 110 120
80 90 100 110 120 130
pF1KE3 FVNGLLDLVKARACGDLRAGKPACALCPLVGGTSTGGPATARCLDCADDLCQACADGHRC
: .. ..: : . .. :. : ..:::. :..:.. ::..:...:.
NP_005 VENYFMRDSGSKAATDAQDANQCCTSCE------DNAPATSYCVECSEPLCETCVEAHQR
130 140 150 160 170 180
140 150 160 170 180 190
pF1KE3 TRQTHTHRVVDLVGYRAGWYDEEARERQAAQCPQHPGEALRFLCQPCSQLLCRECRLDPH
.. :. : : .: . :: .. : : : : ..:. :. : ::.:.:. :
NP_005 VKYTKDHTV-----RSTGPAKSRDGER-TVYCNVHKHEPLVLFCESCDTLTCRDCQLNAH
190 200 210 220 230
200 210 220 230 240 250
pF1KE3 LDHPCLPLAEAVRARRPGLEGLLAGVDNNLVELEAARRVEKEALARLREQAARVGTQVEE
:: : .::: .: : .:. . .. . :. . . . .. .. . :: ..:.
NP_005 KDHQYQFLEDAVRNQRKLLASLVKRLGDKHATLQKSTKEVRSSIRQVSDVQKRVQVDVKM
240 250 260 270 280 290
260 270 280 290 300 310
pF1KE3 AAEGVLRALLAQKQEVLGQLRAHVEAAEEAARERLAELEGREQVARAAAAFARRVLSLGR
: ... : .. .:: .. . :. .:::
NP_005 AILQIMKEL-NKRGRVL---VNDAQKVTEGQQERLERQHWTMTKIQKHQEHILRFASWAL
300 310 320 330 340 350
320 330 340 350 360 370
pF1KE3 EAEILSLEGAIAQRLRQLQGCPWAPGPAPCLLPQLELHPGLLDKNCHLLRLSFEEQQPQK
NP_005 ESDNNTALLLSKKLIYFQLHRALKMIVDPVEPHGEMKFQWDLNAWTKSAEAFGKIVAERP
360 370 380 390 400 410
>>XP_016872587 (OMIM: 605493) PREDICTED: tripartite moti (744 aa)
initn: 567 init1: 248 opt: 329 Z-score: 235.9 bits: 54.3 E(85289): 2.1e-06
Smith-Waterman score: 543; 23.7% identity (52.9% similar) in 797 aa overlap (1-739:1-730)
10 20 30 40 50
pF1KE3 MVSHGSSPS-LLEALSSDFLACKICLEQLRAPKTLPCLHTYCQDCLAQL--ADGGRVRCP
:... .::. .. ....::.:.:::.. . ::.::::::.:. :: . :.. . ::
XP_016 MAKREDSPGPEVQPMDKQFLVCSICLDRYQCPKVLPCLHTFCERCLQNYIPAQSLTLSCP
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE3 ECRETVPVPPEGVASFKTNFFVNGLLDLVKARACGDLRAGKPACALCPLVGGTSTGGPAT
::.: .: .::.....:::...:.. .
XP_016 VCRQTSILPEQGVSALQNNFFISSLMEAM-------------------------------
70 80
120 130 140 150 160 170
pF1KE3 ARCLDCADDLCQACADGHRCTRQTHTHRVVDLVGYRAGWYDEEARERQAAQCPQHPGEAL
: :: . .. : :: :: . .::.: :...
XP_016 -----------QQAPDGAHDPEDPHPLSVV------AG---------RPLSCPNHEGKTM
90 100 110 120
180 190 200 210 220 230
pF1KE3 RFLCQPCSQLLCRECRLDPHLDHPCLPLAEAVRARRPGLEGLLAGVDNNLVELEAARRVE
.: :. : .: ::: : .: . : ..:. .. .:. : .: . : .: :: .
XP_016 EFYCEACETAMCGECRAGEHREHGTVLLRDVVEQHKAALQRQLEAVRGRLPQLSAAIALV
130 140 150 160 170 180
240 250 260 270 280 290
pF1KE3 KEALARLREQAARVGTQVEEAAEGVLRALLAQKQEVLGQLRAHVEAAEEAARERLAEL-E
.:.:. :.. .:. : : . .:: .:: ....:.. : ... . .: : .
XP_016 GGISQQLQERKAEALAQISAAFEDLEQALQQRKQALVSDLETICGAKQKVLQSQLDTLRQ
190 200 210 220 230 240
300 310 320 330 340 350
pF1KE3 GREQVARAAAAFARRVLSLGREAEILSLEGAIAQRLRQL--QGCPWAPGPAPCLLPQLEL
:.:... .. .::...: :: :.: .. . .:: : :. : : : ::.
XP_016 GQEHIG-SSCSFAEQALRLGSAPEVLLVRKHMRERLAALAAQAFPERPHENAQLELVLEV
250 260 270 280 290 300
360 370 380 390 400
pF1KE3 HPGLLDKNCHLLRL-----SFEEQQPQKDGGKDGAGTQGGEESQSRREDEPKTERQGGVQ
:: . .: : . .: .: ... : . . . .. . . : :...
XP_016 D-GLRRSVLNLGALLTTSATAHETVATGEGLRQALVGQPASLTVTTKDKDGRLVRTGSAE
310 320 330 340 350 360
410 420 430 440 450
pF1KE3 PQA---G-DGAQTP---------KEEKAQTTREEGAQTLEEDRAQTPHEDGGPQPHRGGR
.: : ::.. : : . :.: :: : : . :.: :. :
XP_016 LRAEITGPDGTRLPVPVVDHKNGTYELVYTARTEGELLLSVLLYGQPVR-GSPFRVRALR
370 380 390 400 410 420
460 470 480 490
pF1KE3 PNK--------KKKFKG--------RLKSISREPSP--ALGPNLDGSGLLPRPIFYCSFP
:. :.. :. : :.. :.:: . : . . . . .: .
XP_016 PGDLPPSPDDVKRRVKSPGGPGSHVRQKAV-RRPSSMYSTGGKRKDNPIEDELVFRVGSR
430 440 450 460 470
500 510 520 530 540 550
pF1KE3 TRMPGDKRSPRITGLCPFGPREILVADEQNRALKRFSLNGDYKGTVPVPEGCSPCSVAAL
: :. . . :. . .:.::: .:. .. :: .:..: : .: :: . :
XP_016 GREKGEFTN--LQGVSAASSGRIVVADSNNQCIQVFSNEGQFKFRFGV-RGRSP---GQL
480 490 500 510 520 530
560 570 580 590 600 610
pF1KE3 QSAVAFSASARLYLINPNGEVQWRRALS-LSQASHAVAA--LPSGDRVAVSVAGHVEVYN
: .. .... .: . . .: .: .. . ..: : . :::. ::. : .
XP_016 QRPTGVAVDTNGDIIVADYDNRWVSIFSPEGKFKTKIGAGRLMGPKGVAVDRNGHIIVVD
540 550 560 570 580 590
620 630 640 650 660
pF1KE3 MEGSLATRFIPGGK-----ASRGL--RALV---FLTTSPQGHFVGSDWQQNSVVICDGLG
.. . : :.:: ..:: : .. :.... ....: .:....:: . .. :
XP_016 NKSCCVFTFQPNGKLVGRFGGRGATDRHFAGPHFVAVNNKNEIVVTDFHNHSVKVYSADG
600 610 620 630 640 650
670 680 690 700 710 720
pF1KE3 QVVGEYKGPGLHGCQ---PGSVSVDKKGYIFLTLREVNKVVILDPKGSLLGDFLTAYHGL
. . .. . : . : : .:.::..: :... ... ..: .::.:. . :. . :
XP_016 EFLFKFGSHGEGNGQFNAPTGVAVDSNGNIIVADWGNSRIQVFDSSGSFLSYINTSAEPL
660 670 680 690 700 710
730 740 750
pF1KE3 EKPRVTTMVDGRYLVVSLSNGTIHIFRVRSPDS
:. .... ..::.
XP_016 YGPQGLALTSDGHVVVADAGNHCFKAYRYLQ
720 730 740
>>NP_006449 (OMIM: 605493) tripartite motif-containing p (744 aa)
initn: 567 init1: 248 opt: 329 Z-score: 235.9 bits: 54.3 E(85289): 2.1e-06
Smith-Waterman score: 543; 23.7% identity (52.9% similar) in 797 aa overlap (1-739:1-730)
10 20 30 40 50
pF1KE3 MVSHGSSPS-LLEALSSDFLACKICLEQLRAPKTLPCLHTYCQDCLAQL--ADGGRVRCP
:... .::. .. ....::.:.:::.. . ::.::::::.:. :: . :.. . ::
NP_006 MAKREDSPGPEVQPMDKQFLVCSICLDRYQCPKVLPCLHTFCERCLQNYIPAQSLTLSCP
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE3 ECRETVPVPPEGVASFKTNFFVNGLLDLVKARACGDLRAGKPACALCPLVGGTSTGGPAT
::.: .: .::.....:::...:.. .
NP_006 VCRQTSILPEQGVSALQNNFFISSLMEAM-------------------------------
70 80
120 130 140 150 160 170
pF1KE3 ARCLDCADDLCQACADGHRCTRQTHTHRVVDLVGYRAGWYDEEARERQAAQCPQHPGEAL
: :: . .. : :: :: . .::.: :...
NP_006 -----------QQAPDGAHDPEDPHPLSVV------AG---------RPLSCPNHEGKTM
90 100 110 120
180 190 200 210 220 230
pF1KE3 RFLCQPCSQLLCRECRLDPHLDHPCLPLAEAVRARRPGLEGLLAGVDNNLVELEAARRVE
.: :. : .: ::: : .: . : ..:. .. .:. : .: . : .: :: .
NP_006 EFYCEACETAMCGECRAGEHREHGTVLLRDVVEQHKAALQRQLEAVRGRLPQLSAAIALV
130 140 150 160 170 180
240 250 260 270 280 290
pF1KE3 KEALARLREQAARVGTQVEEAAEGVLRALLAQKQEVLGQLRAHVEAAEEAARERLAEL-E
.:.:. :.. .:. : : . .:: .:: ....:.. : ... . .: : .
NP_006 GGISQQLQERKAEALAQISAAFEDLEQALQQRKQALVSDLETICGAKQKVLQSQLDTLRQ
190 200 210 220 230 240
300 310 320 330 340 350
pF1KE3 GREQVARAAAAFARRVLSLGREAEILSLEGAIAQRLRQL--QGCPWAPGPAPCLLPQLEL
:.:... .. .::...: :: :.: .. . .:: : :. : : : ::.
NP_006 GQEHIG-SSCSFAEQALRLGSAPEVLLVRKHMRERLAALAAQAFPERPHENAQLELVLEV
250 260 270 280 290 300
360 370 380 390 400
pF1KE3 HPGLLDKNCHLLRL-----SFEEQQPQKDGGKDGAGTQGGEESQSRREDEPKTERQGGVQ
:: . .: : . .: .: ... : . . . .. . . : :...
NP_006 D-GLRRSVLNLGALLTTSATAHETVATGEGLRQALVGQPASLTVTTKDKDGRLVRTGSAE
310 320 330 340 350 360
410 420 430 440 450
pF1KE3 PQA---G-DGAQTP---------KEEKAQTTREEGAQTLEEDRAQTPHEDGGPQPHRGGR
.: : ::.. : : . :.: :: : : . :.: :. :
NP_006 LRAEITGPDGTRLPVPVVDHKNGTYELVYTARTEGELLLSVLLYGQPVR-GSPFRVRALR
370 380 390 400 410 420
460 470 480 490
pF1KE3 PNK--------KKKFKG--------RLKSISREPSP--ALGPNLDGSGLLPRPIFYCSFP
:. :.. :. : :.. :.:: . : . . . . .: .
NP_006 PGDLPPSPDDVKRRVKSPGGPGSHVRQKAV-RRPSSMYSTGGKRKDNPIEDELVFRVGSR
430 440 450 460 470
500 510 520 530 540 550
pF1KE3 TRMPGDKRSPRITGLCPFGPREILVADEQNRALKRFSLNGDYKGTVPVPEGCSPCSVAAL
: :. . . :. . .:.::: .:. .. :: .:..: : .: :: . :
NP_006 GREKGEFTN--LQGVSAASSGRIVVADSNNQCIQVFSNEGQFKFRFGV-RGRSP---GQL
480 490 500 510 520 530
560 570 580 590 600 610
pF1KE3 QSAVAFSASARLYLINPNGEVQWRRALS-LSQASHAVAA--LPSGDRVAVSVAGHVEVYN
: .. .... .: . . .: .: .. . ..: : . :::. ::. : .
NP_006 QRPTGVAVDTNGDIIVADYDNRWVSIFSPEGKFKTKIGAGRLMGPKGVAVDRNGHIIVVD
540 550 560 570 580 590
620 630 640 650 660
pF1KE3 MEGSLATRFIPGGK-----ASRGL--RALV---FLTTSPQGHFVGSDWQQNSVVICDGLG
.. . : :.:: ..:: : .. :.... ....: .:....:: . .. :
NP_006 NKSCCVFTFQPNGKLVGRFGGRGATDRHFAGPHFVAVNNKNEIVVTDFHNHSVKVYSADG
600 610 620 630 640 650
670 680 690 700 710 720
pF1KE3 QVVGEYKGPGLHGCQ---PGSVSVDKKGYIFLTLREVNKVVILDPKGSLLGDFLTAYHGL
. . .. . : . : : .:.::..: :... ... ..: .::.:. . :. . :
NP_006 EFLFKFGSHGEGNGQFNAPTGVAVDSNGNIIVADWGNSRIQVFDSSGSFLSYINTSAEPL
660 670 680 690 700 710
730 740 750
pF1KE3 EKPRVTTMVDGRYLVVSLSNGTIHIFRVRSPDS
:. .... ..::.
NP_006 YGPQGLALTSDGHVVVADAGNHCFKAYRYLQ
720 730 740
>>NP_001234935 (OMIM: 605493) tripartite motif-containin (744 aa)
initn: 567 init1: 248 opt: 329 Z-score: 235.9 bits: 54.3 E(85289): 2.1e-06
Smith-Waterman score: 543; 23.7% identity (52.9% similar) in 797 aa overlap (1-739:1-730)
10 20 30 40 50
pF1KE3 MVSHGSSPS-LLEALSSDFLACKICLEQLRAPKTLPCLHTYCQDCLAQL--ADGGRVRCP
:... .::. .. ....::.:.:::.. . ::.::::::.:. :: . :.. . ::
NP_001 MAKREDSPGPEVQPMDKQFLVCSICLDRYQCPKVLPCLHTFCERCLQNYIPAQSLTLSCP
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE3 ECRETVPVPPEGVASFKTNFFVNGLLDLVKARACGDLRAGKPACALCPLVGGTSTGGPAT
::.: .: .::.....:::...:.. .
NP_001 VCRQTSILPEQGVSALQNNFFISSLMEAM-------------------------------
70 80
120 130 140 150 160 170
pF1KE3 ARCLDCADDLCQACADGHRCTRQTHTHRVVDLVGYRAGWYDEEARERQAAQCPQHPGEAL
: :: . .. : :: :: . .::.: :...
NP_001 -----------QQAPDGAHDPEDPHPLSVV------AG---------RPLSCPNHEGKTM
90 100 110 120
180 190 200 210 220 230
pF1KE3 RFLCQPCSQLLCRECRLDPHLDHPCLPLAEAVRARRPGLEGLLAGVDNNLVELEAARRVE
.: :. : .: ::: : .: . : ..:. .. .:. : .: . : .: :: .
NP_001 EFYCEACETAMCGECRAGEHREHGTVLLRDVVEQHKAALQRQLEAVRGRLPQLSAAIALV
130 140 150 160 170 180
240 250 260 270 280 290
pF1KE3 KEALARLREQAARVGTQVEEAAEGVLRALLAQKQEVLGQLRAHVEAAEEAARERLAEL-E
.:.:. :.. .:. : : . .:: .:: ....:.. : ... . .: : .
NP_001 GGISQQLQERKAEALAQISAAFEDLEQALQQRKQALVSDLETICGAKQKVLQSQLDTLRQ
190 200 210 220 230 240
300 310 320 330 340 350
pF1KE3 GREQVARAAAAFARRVLSLGREAEILSLEGAIAQRLRQL--QGCPWAPGPAPCLLPQLEL
:.:... .. .::...: :: :.: .. . .:: : :. : : : ::.
NP_001 GQEHIG-SSCSFAEQALRLGSAPEVLLVRKHMRERLAALAAQAFPERPHENAQLELVLEV
250 260 270 280 290 300
360 370 380 390 400
pF1KE3 HPGLLDKNCHLLRL-----SFEEQQPQKDGGKDGAGTQGGEESQSRREDEPKTERQGGVQ
:: . .: : . .: .: ... : . . . .. . . : :...
NP_001 D-GLRRSVLNLGALLTTSATAHETVATGEGLRQALVGQPASLTVTTKDKDGRLVRTGSAE
310 320 330 340 350 360
410 420 430 440 450
pF1KE3 PQA---G-DGAQTP---------KEEKAQTTREEGAQTLEEDRAQTPHEDGGPQPHRGGR
.: : ::.. : : . :.: :: : : . :.: :. :
NP_001 LRAEITGPDGTRLPVPVVDHKNGTYELVYTARTEGELLLSVLLYGQPVR-GSPFRVRALR
370 380 390 400 410 420
460 470 480 490
pF1KE3 PNK--------KKKFKG--------RLKSISREPSP--ALGPNLDGSGLLPRPIFYCSFP
:. :.. :. : :.. :.:: . : . . . . .: .
NP_001 PGDLPPSPDDVKRRVKSPGGPGSHVRQKAV-RRPSSMYSTGGKRKDNPIEDELVFRVGSR
430 440 450 460 470
500 510 520 530 540 550
pF1KE3 TRMPGDKRSPRITGLCPFGPREILVADEQNRALKRFSLNGDYKGTVPVPEGCSPCSVAAL
: :. . . :. . .:.::: .:. .. :: .:..: : .: :: . :
NP_001 GREKGEFTN--LQGVSAASSGRIVVADSNNQCIQVFSNEGQFKFRFGV-RGRSP---GQL
480 490 500 510 520 530
560 570 580 590 600 610
pF1KE3 QSAVAFSASARLYLINPNGEVQWRRALS-LSQASHAVAA--LPSGDRVAVSVAGHVEVYN
: .. .... .: . . .: .: .. . ..: : . :::. ::. : .
NP_001 QRPTGVAVDTNGDIIVADYDNRWVSIFSPEGKFKTKIGAGRLMGPKGVAVDRNGHIIVVD
540 550 560 570 580 590
620 630 640 650 660
pF1KE3 MEGSLATRFIPGGK-----ASRGL--RALV---FLTTSPQGHFVGSDWQQNSVVICDGLG
.. . : :.:: ..:: : .. :.... ....: .:....:: . .. :
NP_001 NKSCCVFTFQPNGKLVGRFGGRGATDRHFAGPHFVAVNNKNEIVVTDFHNHSVKVYSADG
600 610 620 630 640 650
670 680 690 700 710 720
pF1KE3 QVVGEYKGPGLHGCQ---PGSVSVDKKGYIFLTLREVNKVVILDPKGSLLGDFLTAYHGL
. . .. . : . : : .:.::..: :... ... ..: .::.:. . :. . :
NP_001 EFLFKFGSHGEGNGQFNAPTGVAVDSNGNIIVADWGNSRIQVFDSSGSFLSYINTSAEPL
660 670 680 690 700 710
730 740 750
pF1KE3 EKPRVTTMVDGRYLVVSLSNGTIHIFRVRSPDS
:. .... ..::.
NP_001 YGPQGLALTSDGHVVVADAGNHCFKAYRYLQ
720 730 740
>>XP_011518146 (OMIM: 605493) PREDICTED: tripartite moti (744 aa)
initn: 567 init1: 248 opt: 329 Z-score: 235.9 bits: 54.3 E(85289): 2.1e-06
Smith-Waterman score: 543; 23.7% identity (52.9% similar) in 797 aa overlap (1-739:1-730)
10 20 30 40 50
pF1KE3 MVSHGSSPS-LLEALSSDFLACKICLEQLRAPKTLPCLHTYCQDCLAQL--ADGGRVRCP
:... .::. .. ....::.:.:::.. . ::.::::::.:. :: . :.. . ::
XP_011 MAKREDSPGPEVQPMDKQFLVCSICLDRYQCPKVLPCLHTFCERCLQNYIPAQSLTLSCP
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE3 ECRETVPVPPEGVASFKTNFFVNGLLDLVKARACGDLRAGKPACALCPLVGGTSTGGPAT
::.: .: .::.....:::...:.. .
XP_011 VCRQTSILPEQGVSALQNNFFISSLMEAM-------------------------------
70 80
120 130 140 150 160 170
pF1KE3 ARCLDCADDLCQACADGHRCTRQTHTHRVVDLVGYRAGWYDEEARERQAAQCPQHPGEAL
: :: . .. : :: :: . .::.: :...
XP_011 -----------QQAPDGAHDPEDPHPLSVV------AG---------RPLSCPNHEGKTM
90 100 110 120
180 190 200 210 220 230
pF1KE3 RFLCQPCSQLLCRECRLDPHLDHPCLPLAEAVRARRPGLEGLLAGVDNNLVELEAARRVE
.: :. : .: ::: : .: . : ..:. .. .:. : .: . : .: :: .
XP_011 EFYCEACETAMCGECRAGEHREHGTVLLRDVVEQHKAALQRQLEAVRGRLPQLSAAIALV
130 140 150 160 170 180
240 250 260 270 280 290
pF1KE3 KEALARLREQAARVGTQVEEAAEGVLRALLAQKQEVLGQLRAHVEAAEEAARERLAEL-E
.:.:. :.. .:. : : . .:: .:: ....:.. : ... . .: : .
XP_011 GGISQQLQERKAEALAQISAAFEDLEQALQQRKQALVSDLETICGAKQKVLQSQLDTLRQ
190 200 210 220 230 240
300 310 320 330 340 350
pF1KE3 GREQVARAAAAFARRVLSLGREAEILSLEGAIAQRLRQL--QGCPWAPGPAPCLLPQLEL
:.:... .. .::...: :: :.: .. . .:: : :. : : : ::.
XP_011 GQEHIG-SSCSFAEQALRLGSAPEVLLVRKHMRERLAALAAQAFPERPHENAQLELVLEV
250 260 270 280 290 300
360 370 380 390 400
pF1KE3 HPGLLDKNCHLLRL-----SFEEQQPQKDGGKDGAGTQGGEESQSRREDEPKTERQGGVQ
:: . .: : . .: .: ... : . . . .. . . : :...
XP_011 D-GLRRSVLNLGALLTTSATAHETVATGEGLRQALVGQPASLTVTTKDKDGRLVRTGSAE
310 320 330 340 350 360
410 420 430 440 450
pF1KE3 PQA---G-DGAQTP---------KEEKAQTTREEGAQTLEEDRAQTPHEDGGPQPHRGGR
.: : ::.. : : . :.: :: : : . :.: :. :
XP_011 LRAEITGPDGTRLPVPVVDHKNGTYELVYTARTEGELLLSVLLYGQPVR-GSPFRVRALR
370 380 390 400 410 420
460 470 480 490
pF1KE3 PNK--------KKKFKG--------RLKSISREPSP--ALGPNLDGSGLLPRPIFYCSFP
:. :.. :. : :.. :.:: . : . . . . .: .
XP_011 PGDLPPSPDDVKRRVKSPGGPGSHVRQKAV-RRPSSMYSTGGKRKDNPIEDELVFRVGSR
430 440 450 460 470
500 510 520 530 540 550
pF1KE3 TRMPGDKRSPRITGLCPFGPREILVADEQNRALKRFSLNGDYKGTVPVPEGCSPCSVAAL
: :. . . :. . .:.::: .:. .. :: .:..: : .: :: . :
XP_011 GREKGEFTN--LQGVSAASSGRIVVADSNNQCIQVFSNEGQFKFRFGV-RGRSP---GQL
480 490 500 510 520 530
560 570 580 590 600 610
pF1KE3 QSAVAFSASARLYLINPNGEVQWRRALS-LSQASHAVAA--LPSGDRVAVSVAGHVEVYN
: .. .... .: . . .: .: .. . ..: : . :::. ::. : .
XP_011 QRPTGVAVDTNGDIIVADYDNRWVSIFSPEGKFKTKIGAGRLMGPKGVAVDRNGHIIVVD
540 550 560 570 580 590
620 630 640 650 660
pF1KE3 MEGSLATRFIPGGK-----ASRGL--RALV---FLTTSPQGHFVGSDWQQNSVVICDGLG
.. . : :.:: ..:: : .. :.... ....: .:....:: . .. :
XP_011 NKSCCVFTFQPNGKLVGRFGGRGATDRHFAGPHFVAVNNKNEIVVTDFHNHSVKVYSADG
600 610 620 630 640 650
670 680 690 700 710 720
pF1KE3 QVVGEYKGPGLHGCQ---PGSVSVDKKGYIFLTLREVNKVVILDPKGSLLGDFLTAYHGL
. . .. . : . : : .:.::..: :... ... ..: .::.:. . :. . :
XP_011 EFLFKFGSHGEGNGQFNAPTGVAVDSNGNIIVADWGNSRIQVFDSSGSFLSYINTSAEPL
660 670 680 690 700 710
730 740 750
pF1KE3 EKPRVTTMVDGRYLVVSLSNGTIHIFRVRSPDS
:. .... ..::.
XP_011 YGPQGLALTSDGHVVVADAGNHCFKAYRYLQ
720 730 740
755 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 08:36:40 2016 done: Sun Nov 6 08:36:42 2016
Total Scan time: 13.430 Total Display time: 0.180
Function used was FASTA [36.3.4 Apr, 2011]