Result of FASTA (omim) for
pFN21AE3952
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3952, 1711 aa
1>>>pF1KE3952 1711 - 1711 aa - 1711 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 20.3523+/-0.000576; mu= -48.8726+/- 0.036
mean_var=967.0824+/-200.172, 0's: 0 Z-trim(123.1): 214 B-trim: 33 in 1/60
Lambda= 0.041242
statistics sampled from 42179 (42401) to 42179 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.76), E-opt: 0.2 (0.497), width: 16
Scan time: 25.770
The best scores are: opt bits E(85289)
NP_068765 (OMIM: 300688) BCL-6 corepressor-like pr (1711) 11570 705.6 9.6e-202
XP_005262511 (OMIM: 300688) PREDICTED: BCL-6 corep (1785) 9684 593.4 6e-168
XP_016885211 (OMIM: 300688) PREDICTED: BCL-6 corep (1785) 9684 593.4 6e-168
XP_005262509 (OMIM: 300688) PREDICTED: BCL-6 corep (1785) 9684 593.4 6e-168
XP_006724839 (OMIM: 300688) PREDICTED: BCL-6 corep (1785) 9684 593.4 6e-168
XP_005262510 (OMIM: 300688) PREDICTED: BCL-6 corep (1785) 9684 593.4 6e-168
XP_006724840 (OMIM: 300688) PREDICTED: BCL-6 corep (1785) 9684 593.4 6e-168
XP_016885210 (OMIM: 300688) PREDICTED: BCL-6 corep (1785) 9684 593.4 6e-168
NP_001171701 (OMIM: 300688) BCL-6 corepressor-like (1785) 9684 593.4 6e-168
XP_005262512 (OMIM: 300688) PREDICTED: BCL-6 corep (1785) 9684 593.4 6e-168
XP_006724842 (OMIM: 300688) PREDICTED: BCL-6 corep (1687) 9013 553.5 6e-156
XP_005262513 (OMIM: 300688) PREDICTED: BCL-6 corep (1655) 8309 511.6 2.4e-143
NP_001116855 (OMIM: 300166,300485,309800) BCL-6 co (1721) 1147 85.5 4.7e-15
XP_016885104 (OMIM: 300166,300485,309800) PREDICTE (1721) 1147 85.5 4.7e-15
NP_060215 (OMIM: 300166,300485,309800) BCL-6 corep (1721) 1147 85.5 4.7e-15
NP_001116856 (OMIM: 300166,300485,309800) BCL-6 co (1703) 1123 84.0 1.3e-14
XP_005272677 (OMIM: 300166,300485,309800) PREDICTE (1703) 1123 84.0 1.3e-14
XP_005272676 (OMIM: 300166,300485,309800) PREDICTE (1737) 1108 83.1 2.4e-14
XP_005272675 (OMIM: 300166,300485,309800) PREDICTE (1755) 1080 81.5 7.6e-14
NP_001116857 (OMIM: 300166,300485,309800) BCL-6 co (1755) 1080 81.5 7.6e-14
XP_011542232 (OMIM: 300166,300485,309800) PREDICTE (1755) 1080 81.5 7.6e-14
XP_006724599 (OMIM: 300166,300485,309800) PREDICTE (1755) 1080 81.5 7.6e-14
XP_011542231 (OMIM: 300166,300485,309800) PREDICTE (1755) 1080 81.5 7.6e-14
XP_005272673 (OMIM: 300166,300485,309800) PREDICTE (1755) 1080 81.5 7.6e-14
XP_011542233 (OMIM: 300166,300485,309800) PREDICTE (1755) 1080 81.5 7.6e-14
XP_016885105 (OMIM: 300166,300485,309800) PREDICTE (1659) 835 66.9 1.8e-09
NP_002448 (OMIM: 158370) mucin-2 precursor [Homo s (5289) 564 51.0 0.00033
NP_006653 (OMIM: 136140,611421) helicase SRCAP [Ho (3230) 540 49.5 0.0006
XP_011536691 (OMIM: 601234) PREDICTED: nascent pol (2078) 511 47.7 0.0014
XP_006719476 (OMIM: 601234) PREDICTED: nascent pol (2082) 511 47.7 0.0014
XP_006719475 (OMIM: 601234) PREDICTED: nascent pol (2082) 511 47.7 0.0014
XP_006719477 (OMIM: 601234) PREDICTED: nascent pol (2082) 511 47.7 0.0014
NP_940881 (OMIM: 611166) tetra-peptide repeat home ( 411) 453 43.8 0.0038
XP_011525185 (OMIM: 605690) PREDICTED: glioma tumo (1501) 468 45.0 0.0061
NP_001035194 (OMIM: 608424) mucin-17 precursor [Ho (4493) 480 46.0 0.0093
>>NP_068765 (OMIM: 300688) BCL-6 corepressor-like protei (1711 aa)
initn: 11570 init1: 11570 opt: 11570 Z-score: 3742.9 bits: 705.6 E(85289): 9.6e-202
Smith-Waterman score: 11570; 100.0% identity (100.0% similar) in 1711 aa overlap (1-1711:1-1711)
10 20 30 40 50 60
pF1KE3 MISTAPLYSGVHNWTSSDRIRMCGINEERRAPLSDEESTTGDCQHFGSQEFCVSSSFSKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 MISTAPLYSGVHNWTSSDRIRMCGINEERRAPLSDEESTTGDCQHFGSQEFCVSSSFSKV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 ELTAVGSGSNARGADPDGSATEKLGHKSEDKPDDPQPKMDYAGNVAEAEGLLVPLSSPGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 ELTAVGSGSNARGADPDGSATEKLGHKSEDKPDDPQPKMDYAGNVAEAEGLLVPLSSPGD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 GLKLPASDSAEASNSRADCSWTPLNTQMSKQVDCSPAGVKALDSRQGVGEKNTFILATLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 GLKLPASDSAEASNSRADCSWTPLNTQMSKQVDCSPAGVKALDSRQGVGEKNTFILATLG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 TGVPVEGTLPLVTTNFSPLPAPICPPAPGSASVPHSVPDAFQVPLSVPAPVPHSGLVPVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 TGVPVEGTLPLVTTNFSPLPAPICPPAPGSASVPHSVPDAFQVPLSVPAPVPHSGLVPVQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 VATSVPAPSPPLAPVPALAPAPPSVPTLISDSNPLSVSASVLVPVPASAPPSGPVPLSAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 VATSVPAPSPPLAPVPALAPAPPSVPTLISDSNPLSVSASVLVPVPASAPPSGPVPLSAP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 APAPLSVPVSAPPLALIQAPVPPSAPTLVLAPVPTPVLAPMPASTPPAAPAPPSVPMPTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 APAPLSVPVSAPPLALIQAPVPPSAPTLVLAPVPTPVLAPMPASTPPAAPAPPSVPMPTP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 TPSSGPPSTPTLIPAFAPTPVPAPTPAPIFTPAPTPMPAATPAAIPTSAPIPASFSLSRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 TPSSGPPSTPTLIPAFAPTPVPAPTPAPIFTPAPTPMPAATPAAIPTSAPIPASFSLSRV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 CFPAAQAPAMQKVPLSFQPGTVLTPSQPLVYIPPPSCGQPLSVATLPTTLGVSSTLTLPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 CFPAAQAPAMQKVPLSFQPGTVLTPSQPLVYIPPPSCGQPLSVATLPTTLGVSSTLTLPV
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 LPSYLQDRCLPGVLASPELRSYPYAFSVARPLTSDSKLVSLEVNRLPCTSPSGSTTTQPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 LPSYLQDRCLPGVLASPELRSYPYAFSVARPLTSDSKLVSLEVNRLPCTSPSGSTTTQPA
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 PDGVPGPLADTSLVTASAKVLPTPQPLLPAPSGSSAPPHPAKMPSGTEQQTEGTSVTFSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 PDGVPGPLADTSLVTASAKVLPTPQPLLPAPSGSSAPPHPAKMPSGTEQQTEGTSVTFSP
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 LKSPPQLEREMASPPECSEMPLDLSSKSNRQKLPLPNQRKTPPMPVLTPVHTSSKALLST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 LKSPPQLEREMASPPECSEMPLDLSSKSNRQKLPLPNQRKTPPMPVLTPVHTSSKALLST
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 VLSRSQRTTQAAGGNVTSCLGSTSSPFVIFPEIVRNGDPSTWVKNSTALISTIPGTYVGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 VLSRSQRTTQAAGGNVTSCLGSTSSPFVIFPEIVRNGDPSTWVKNSTALISTIPGTYVGV
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 ANPVPASLLLNKDPNLGLNRDPRHLPKQEPISIIDQGEPKGTGATCGKKGSQAGAEGQPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 ANPVPASLLLNKDPNLGLNRDPRHLPKQEPISIIDQGEPKGTGATCGKKGSQAGAEGQPS
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE3 TVKRYTPARIAPGLPGCQTKELSLWKPTGPANIYPRCSVNGKPTSTQVLPVGWSPYHQAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 TVKRYTPARIAPGLPGCQTKELSLWKPTGPANIYPRCSVNGKPTSTQVLPVGWSPYHQAS
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE3 LLSIGISSAGQLTPSQGAPIRPTSVVSEFSGVPSLSSSEAVHGLPEGQPRPGGSFVPEQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 LLSIGISSAGQLTPSQGAPIRPTSVVSEFSGVPSLSSSEAVHGLPEGQPRPGGSFVPEQD
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE3 PVTKNKTCRIAAKPYEEQVNPVLLTLSPQTGTLALSVQPSGGDIRMNQGPEESESHLCSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 PVTKNKTCRIAAKPYEEQVNPVLLTLSPQTGTLALSVQPSGGDIRMNQGPEESESHLCSD
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE3 STPKMEGPQGACGLKLAGDTKPKNQVLATYMSHELVLATPQNLPKMPELPLLPHDSHPKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 STPKMEGPQGACGLKLAGDTKPKNQVLATYMSHELVLATPQNLPKMPELPLLPHDSHPKE
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE3 LILDVVPSSRRGSSTERPQLGSQVDLGRVKMEKVDGDVVFNLATCFRADGLPVAPQRGQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 LILDVVPSSRRGSSTERPQLGSQVDLGRVKMEKVDGDVVFNLATCFRADGLPVAPQRGQA
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE3 EVRAKAGQARVKQESVGVFACKNKWQPDDVTESLPPKKMKCGKEKDSEEQQLQPQAKAVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 EVRAKAGQARVKQESVGVFACKNKWQPDDVTESLPPKKMKCGKEKDSEEQQLQPQAKAVV
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE3 RSSHRPKCRKLPSDPQESTKKSPRGASDSGKEHNGVRGKHKHRKPTKPESQSPGKRADSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 RSSHRPKCRKLPSDPQESTKKSPRGASDSGKEHNGVRGKHKHRKPTKPESQSPGKRADSH
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE3 EEGSLEKKAKSSFRDFIPVVLSTRTRSQSGSICSSFAGMADSDMGSQEVFPTEEEEEVTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 EEGSLEKKAKSSFRDFIPVVLSTRTRSQSGSICSSFAGMADSDMGSQEVFPTEEEEEVTP
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE3 TPAKRRKVRKTQRDTQYRSHHAQDKSLLSQGRRHLWRAREMPWRTEAARQMWDTNEEEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 TPAKRRKVRKTQRDTQYRSHHAQDKSLLSQGRRHLWRAREMPWRTEAARQMWDTNEEEEE
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE3 EEEEGLLKRKKRRRQKSRKYQTGEYLTEQEDEQRRKGRADLKARKQKTSSSQSLEHRLRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 EEEEGLLKRKKRRRQKSRKYQTGEYLTEQEDEQRRKGRADLKARKQKTSSSQSLEHRLRN
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KE3 RNLLLPNKVQGISDSPNGFLPNNLEEPACLENSEKPSGKRKCKTKHMATVSEEAKDVVLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 RNLLLPNKVQGISDSPNGFLPNNLEEPACLENSEKPSGKRKCKTKHMATVSEEAKDVVLY
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KE3 CLQKDSEDVNHRDNAGYTALHEACSRGWTDILNILLEHGANVNCSAQDGTRPVHDAVVND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 CLQKDSEDVNHRDNAGYTALHEACSRGWTDILNILLEHGANVNCSAQDGTRPVHDAVVND
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KE3 NLETIWLLLSYGADPTLATYSGQTAMKLASSDTMKRFLSDHLSDLQGRAEGDPGVSWDFY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 NLETIWLLLSYGADPTLATYSGQTAMKLASSDTMKRFLSDHLSDLQGRAEGDPGVSWDFY
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KE3 SSSVLEEKDGFACDLLHNPPGSSDQEGDDPMEEDDFMFELSDKPLLPCYNLQVSVSRGPC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 SSSVLEEKDGFACDLLHNPPGSSDQEGDDPMEEDDFMFELSDKPLLPCYNLQVSVSRGPC
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KE3 NWFLFSDVLKRLKLSSRIFQARFPHFEITTMPKAEFYRQVASSQLLTPAERPGGLDDRSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 NWFLFSDVLKRLKLSSRIFQARFPHFEITTMPKAEFYRQVASSQLLTPAERPGGLDDRSP
1630 1640 1650 1660 1670 1680
1690 1700 1710
pF1KE3 PGSSETVELVRYEPDLLRLLGSEVEFQSCNS
:::::::::::::::::::::::::::::::
NP_068 PGSSETVELVRYEPDLLRLLGSEVEFQSCNS
1690 1700 1710
>>XP_005262511 (OMIM: 300688) PREDICTED: BCL-6 corepress (1785 aa)
initn: 9684 init1: 9684 opt: 9684 Z-score: 3136.2 bits: 593.4 E(85289): 6e-168
Smith-Waterman score: 11129; 95.8% identity (95.8% similar) in 1743 aa overlap (1-1669:1-1743)
10 20 30 40 50 60
pF1KE3 MISTAPLYSGVHNWTSSDRIRMCGINEERRAPLSDEESTTGDCQHFGSQEFCVSSSFSKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MISTAPLYSGVHNWTSSDRIRMCGINEERRAPLSDEESTTGDCQHFGSQEFCVSSSFSKV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 ELTAVGSGSNARGADPDGSATEKLGHKSEDKPDDPQPKMDYAGNVAEAEGLLVPLSSPGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ELTAVGSGSNARGADPDGSATEKLGHKSEDKPDDPQPKMDYAGNVAEAEGLLVPLSSPGD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 GLKLPASDSAEASNSRADCSWTPLNTQMSKQVDCSPAGVKALDSRQGVGEKNTFILATLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GLKLPASDSAEASNSRADCSWTPLNTQMSKQVDCSPAGVKALDSRQGVGEKNTFILATLG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 TGVPVEGTLPLVTTNFSPLPAPICPPAPGSASVPHSVPDAFQVPLSVPAPVPHSGLVPVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TGVPVEGTLPLVTTNFSPLPAPICPPAPGSASVPHSVPDAFQVPLSVPAPVPHSGLVPVQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 VATSVPAPSPPLAPVPALAPAPPSVPTLISDSNPLSVSASVLVPVPASAPPSGPVPLSAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VATSVPAPSPPLAPVPALAPAPPSVPTLISDSNPLSVSASVLVPVPASAPPSGPVPLSAP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 APAPLSVPVSAPPLALIQAPVPPSAPTLVLAPVPTPVLAPMPASTPPAAPAPPSVPMPTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 APAPLSVPVSAPPLALIQAPVPPSAPTLVLAPVPTPVLAPMPASTPPAAPAPPSVPMPTP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 TPSSGPPSTPTLIPAFAPTPVPAPTPAPIFTPAPTPMPAATPAAIPTSAPIPASFSLSRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TPSSGPPSTPTLIPAFAPTPVPAPTPAPIFTPAPTPMPAATPAAIPTSAPIPASFSLSRV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 CFPAAQAPAMQKVPLSFQPGTVLTPSQPLVYIPPPSCGQPLSVATLPTTLGVSSTLTLPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CFPAAQAPAMQKVPLSFQPGTVLTPSQPLVYIPPPSCGQPLSVATLPTTLGVSSTLTLPV
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 LPSYLQDRCLPGVLASPELRSYPYAFSVARPLTSDSKLVSLEVNRLPCTSPSGSTTTQPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LPSYLQDRCLPGVLASPELRSYPYAFSVARPLTSDSKLVSLEVNRLPCTSPSGSTTTQPA
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 PDGVPGPLADTSLVTASAKVLPTPQPLLPAPSGSSAPPHPAKMPSGTEQQTEGTSVTFSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PDGVPGPLADTSLVTASAKVLPTPQPLLPAPSGSSAPPHPAKMPSGTEQQTEGTSVTFSP
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 LKSPPQLEREMASPPECSEMPLDLSSKSNRQKLPLPNQRKTPPMPVLTPVHTSSKALLST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LKSPPQLEREMASPPECSEMPLDLSSKSNRQKLPLPNQRKTPPMPVLTPVHTSSKALLST
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 VLSRSQRTTQAAGGNVTSCLGSTSSPFVIFPEIVRNGDPSTWVKNSTALISTIPGTYVGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VLSRSQRTTQAAGGNVTSCLGSTSSPFVIFPEIVRNGDPSTWVKNSTALISTIPGTYVGV
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 ANPVPASLLLNKDPNLGLNRDPRHLPKQEPISIIDQGEPKGTGATCGKKGSQAGAEGQPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ANPVPASLLLNKDPNLGLNRDPRHLPKQEPISIIDQGEPKGTGATCGKKGSQAGAEGQPS
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE3 TVKRYTPARIAPGLPGCQTKELSLWKPTGPANIYPRCSVNGKPTSTQVLPVGWSPYHQAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TVKRYTPARIAPGLPGCQTKELSLWKPTGPANIYPRCSVNGKPTSTQVLPVGWSPYHQAS
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE3 LLSIGISSAGQLTPSQGAPIRPTSVVSEFSGVPSLSSSEAVHGLPEGQPRPGGSFVPEQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LLSIGISSAGQLTPSQGAPIRPTSVVSEFSGVPSLSSSEAVHGLPEGQPRPGGSFVPEQD
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE3 PVTKNKTCRIAAKPYEEQVNPVLLTLSPQTGTLALSVQPSGGDIRMNQGPEESESHLCSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PVTKNKTCRIAAKPYEEQVNPVLLTLSPQTGTLALSVQPSGGDIRMNQGPEESESHLCSD
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE3 STPKMEGPQGACGLKLAGDTKPKNQVLATYMSHELVLATPQNLPKMPELPLLPHDSHPKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 STPKMEGPQGACGLKLAGDTKPKNQVLATYMSHELVLATPQNLPKMPELPLLPHDSHPKE
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE3 LILDVVPSSRRGSSTERPQLGSQVDLGRVKMEKVDGDVVFNLATCFRADGLPVAPQRGQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LILDVVPSSRRGSSTERPQLGSQVDLGRVKMEKVDGDVVFNLATCFRADGLPVAPQRGQA
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE3 EVRAKAGQARVKQESVGVFACKNKWQPDDVTESLPPKKMKCGKEKDSEEQQLQPQAKAVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EVRAKAGQARVKQESVGVFACKNKWQPDDVTESLPPKKMKCGKEKDSEEQQLQPQAKAVV
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE3 RSSHRPKCRKLPSDPQESTKKSPRGASDSGKEHNGVRGKHKHRKPTKPESQSPGKRADSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RSSHRPKCRKLPSDPQESTKKSPRGASDSGKEHNGVRGKHKHRKPTKPESQSPGKRADSH
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE3 EEGSLEKKAKSSFRDFIPVVLSTRTRSQSGSICSSFAGMADSDMGSQEVFPTEEEEEVTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EEGSLEKKAKSSFRDFIPVVLSTRTRSQSGSICSSFAGMADSDMGSQEVFPTEEEEEVTP
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE3 TPAKRRKVRKTQRDTQYRSHHAQDKSLLSQGRRHLWRAREMPWRTEAARQMWDTNEEEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TPAKRRKVRKTQRDTQYRSHHAQDKSLLSQGRRHLWRAREMPWRTEAARQMWDTNEEEEE
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE3 EEEEGLLKRKKRRRQKSRKYQTGEYLTEQEDEQRRKGRADLKARKQKTSSSQSLEHRLRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EEEEGLLKRKKRRRQKSRKYQTGEYLTEQEDEQRRKGRADLKARKQKTSSSQSLEHRLRN
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430
pF1KE3 RNLLLPNKVQGISDSPNGFLPNNLEEPACLENSEKPSGKRKCKTKHMATVSEEAK-----
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RNLLLPNKVQGISDSPNGFLPNNLEEPACLENSEKPSGKRKCKTKHMATVSEEAKGKGRW
1390 1400 1410 1420 1430 1440
pF1KE3 ------------------------------------------------------------
XP_005 SQQKTRSPKSPTPVKPTEPCTPSKSRSASSEEASESPTARQIPPEARRLIVNKNAGETLL
1450 1460 1470 1480 1490 1500
1440 1450 1460 1470 1480
pF1KE3 ---------DVVLYCLQKDSEDVNHRDNAGYTALHEACSRGWTDILNILLEHGANVNCSA
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QRAARLGYKDVVLYCLQKDSEDVNHRDNAGYTALHEACSRGWTDILNILLEHGANVNCSA
1510 1520 1530 1540 1550 1560
1490 1500 1510 1520 1530 1540
pF1KE3 QDGTRPVHDAVVNDNLETIWLLLSYGADPTLATYSGQTAMKLASSDTMKRFLSDHLSDLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QDGTRPVHDAVVNDNLETIWLLLSYGADPTLATYSGQTAMKLASSDTMKRFLSDHLSDLQ
1570 1580 1590 1600 1610 1620
1550 1560 1570 1580 1590 1600
pF1KE3 GRAEGDPGVSWDFYSSSVLEEKDGFACDLLHNPPGSSDQEGDDPMEEDDFMFELSDKPLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GRAEGDPGVSWDFYSSSVLEEKDGFACDLLHNPPGSSDQEGDDPMEEDDFMFELSDKPLL
1630 1640 1650 1660 1670 1680
1610 1620 1630 1640 1650 1660
pF1KE3 PCYNLQVSVSRGPCNWFLFSDVLKRLKLSSRIFQARFPHFEITTMPKAEFYRQVASSQLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PCYNLQVSVSRGPCNWFLFSDVLKRLKLSSRIFQARFPHFEITTMPKAEFYRQVASSQLL
1690 1700 1710 1720 1730 1740
1670 1680 1690 1700 1710
pF1KE3 TPAERPGGLDDRSPPGSSETVELVRYEPDLLRLLGSEVEFQSCNS
:::
XP_005 TPAERPGGLDDRSPPGSSETVELVRYEPDLLRLLGSEVEFQSCNS
1750 1760 1770 1780
>>XP_016885211 (OMIM: 300688) PREDICTED: BCL-6 corepress (1785 aa)
initn: 9684 init1: 9684 opt: 9684 Z-score: 3136.2 bits: 593.4 E(85289): 6e-168
Smith-Waterman score: 11129; 95.8% identity (95.8% similar) in 1743 aa overlap (1-1669:1-1743)
10 20 30 40 50 60
pF1KE3 MISTAPLYSGVHNWTSSDRIRMCGINEERRAPLSDEESTTGDCQHFGSQEFCVSSSFSKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MISTAPLYSGVHNWTSSDRIRMCGINEERRAPLSDEESTTGDCQHFGSQEFCVSSSFSKV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 ELTAVGSGSNARGADPDGSATEKLGHKSEDKPDDPQPKMDYAGNVAEAEGLLVPLSSPGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELTAVGSGSNARGADPDGSATEKLGHKSEDKPDDPQPKMDYAGNVAEAEGLLVPLSSPGD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 GLKLPASDSAEASNSRADCSWTPLNTQMSKQVDCSPAGVKALDSRQGVGEKNTFILATLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLKLPASDSAEASNSRADCSWTPLNTQMSKQVDCSPAGVKALDSRQGVGEKNTFILATLG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 TGVPVEGTLPLVTTNFSPLPAPICPPAPGSASVPHSVPDAFQVPLSVPAPVPHSGLVPVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TGVPVEGTLPLVTTNFSPLPAPICPPAPGSASVPHSVPDAFQVPLSVPAPVPHSGLVPVQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 VATSVPAPSPPLAPVPALAPAPPSVPTLISDSNPLSVSASVLVPVPASAPPSGPVPLSAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VATSVPAPSPPLAPVPALAPAPPSVPTLISDSNPLSVSASVLVPVPASAPPSGPVPLSAP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 APAPLSVPVSAPPLALIQAPVPPSAPTLVLAPVPTPVLAPMPASTPPAAPAPPSVPMPTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 APAPLSVPVSAPPLALIQAPVPPSAPTLVLAPVPTPVLAPMPASTPPAAPAPPSVPMPTP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 TPSSGPPSTPTLIPAFAPTPVPAPTPAPIFTPAPTPMPAATPAAIPTSAPIPASFSLSRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TPSSGPPSTPTLIPAFAPTPVPAPTPAPIFTPAPTPMPAATPAAIPTSAPIPASFSLSRV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 CFPAAQAPAMQKVPLSFQPGTVLTPSQPLVYIPPPSCGQPLSVATLPTTLGVSSTLTLPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CFPAAQAPAMQKVPLSFQPGTVLTPSQPLVYIPPPSCGQPLSVATLPTTLGVSSTLTLPV
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 LPSYLQDRCLPGVLASPELRSYPYAFSVARPLTSDSKLVSLEVNRLPCTSPSGSTTTQPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LPSYLQDRCLPGVLASPELRSYPYAFSVARPLTSDSKLVSLEVNRLPCTSPSGSTTTQPA
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 PDGVPGPLADTSLVTASAKVLPTPQPLLPAPSGSSAPPHPAKMPSGTEQQTEGTSVTFSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PDGVPGPLADTSLVTASAKVLPTPQPLLPAPSGSSAPPHPAKMPSGTEQQTEGTSVTFSP
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 LKSPPQLEREMASPPECSEMPLDLSSKSNRQKLPLPNQRKTPPMPVLTPVHTSSKALLST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKSPPQLEREMASPPECSEMPLDLSSKSNRQKLPLPNQRKTPPMPVLTPVHTSSKALLST
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 VLSRSQRTTQAAGGNVTSCLGSTSSPFVIFPEIVRNGDPSTWVKNSTALISTIPGTYVGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLSRSQRTTQAAGGNVTSCLGSTSSPFVIFPEIVRNGDPSTWVKNSTALISTIPGTYVGV
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 ANPVPASLLLNKDPNLGLNRDPRHLPKQEPISIIDQGEPKGTGATCGKKGSQAGAEGQPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ANPVPASLLLNKDPNLGLNRDPRHLPKQEPISIIDQGEPKGTGATCGKKGSQAGAEGQPS
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE3 TVKRYTPARIAPGLPGCQTKELSLWKPTGPANIYPRCSVNGKPTSTQVLPVGWSPYHQAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TVKRYTPARIAPGLPGCQTKELSLWKPTGPANIYPRCSVNGKPTSTQVLPVGWSPYHQAS
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE3 LLSIGISSAGQLTPSQGAPIRPTSVVSEFSGVPSLSSSEAVHGLPEGQPRPGGSFVPEQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLSIGISSAGQLTPSQGAPIRPTSVVSEFSGVPSLSSSEAVHGLPEGQPRPGGSFVPEQD
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE3 PVTKNKTCRIAAKPYEEQVNPVLLTLSPQTGTLALSVQPSGGDIRMNQGPEESESHLCSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PVTKNKTCRIAAKPYEEQVNPVLLTLSPQTGTLALSVQPSGGDIRMNQGPEESESHLCSD
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE3 STPKMEGPQGACGLKLAGDTKPKNQVLATYMSHELVLATPQNLPKMPELPLLPHDSHPKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 STPKMEGPQGACGLKLAGDTKPKNQVLATYMSHELVLATPQNLPKMPELPLLPHDSHPKE
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE3 LILDVVPSSRRGSSTERPQLGSQVDLGRVKMEKVDGDVVFNLATCFRADGLPVAPQRGQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LILDVVPSSRRGSSTERPQLGSQVDLGRVKMEKVDGDVVFNLATCFRADGLPVAPQRGQA
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE3 EVRAKAGQARVKQESVGVFACKNKWQPDDVTESLPPKKMKCGKEKDSEEQQLQPQAKAVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EVRAKAGQARVKQESVGVFACKNKWQPDDVTESLPPKKMKCGKEKDSEEQQLQPQAKAVV
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE3 RSSHRPKCRKLPSDPQESTKKSPRGASDSGKEHNGVRGKHKHRKPTKPESQSPGKRADSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RSSHRPKCRKLPSDPQESTKKSPRGASDSGKEHNGVRGKHKHRKPTKPESQSPGKRADSH
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE3 EEGSLEKKAKSSFRDFIPVVLSTRTRSQSGSICSSFAGMADSDMGSQEVFPTEEEEEVTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEGSLEKKAKSSFRDFIPVVLSTRTRSQSGSICSSFAGMADSDMGSQEVFPTEEEEEVTP
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE3 TPAKRRKVRKTQRDTQYRSHHAQDKSLLSQGRRHLWRAREMPWRTEAARQMWDTNEEEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TPAKRRKVRKTQRDTQYRSHHAQDKSLLSQGRRHLWRAREMPWRTEAARQMWDTNEEEEE
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE3 EEEEGLLKRKKRRRQKSRKYQTGEYLTEQEDEQRRKGRADLKARKQKTSSSQSLEHRLRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEEEGLLKRKKRRRQKSRKYQTGEYLTEQEDEQRRKGRADLKARKQKTSSSQSLEHRLRN
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430
pF1KE3 RNLLLPNKVQGISDSPNGFLPNNLEEPACLENSEKPSGKRKCKTKHMATVSEEAK-----
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RNLLLPNKVQGISDSPNGFLPNNLEEPACLENSEKPSGKRKCKTKHMATVSEEAKGKGRW
1390 1400 1410 1420 1430 1440
pF1KE3 ------------------------------------------------------------
XP_016 SQQKTRSPKSPTPVKPTEPCTPSKSRSASSEEASESPTARQIPPEARRLIVNKNAGETLL
1450 1460 1470 1480 1490 1500
1440 1450 1460 1470 1480
pF1KE3 ---------DVVLYCLQKDSEDVNHRDNAGYTALHEACSRGWTDILNILLEHGANVNCSA
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QRAARLGYKDVVLYCLQKDSEDVNHRDNAGYTALHEACSRGWTDILNILLEHGANVNCSA
1510 1520 1530 1540 1550 1560
1490 1500 1510 1520 1530 1540
pF1KE3 QDGTRPVHDAVVNDNLETIWLLLSYGADPTLATYSGQTAMKLASSDTMKRFLSDHLSDLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QDGTRPVHDAVVNDNLETIWLLLSYGADPTLATYSGQTAMKLASSDTMKRFLSDHLSDLQ
1570 1580 1590 1600 1610 1620
1550 1560 1570 1580 1590 1600
pF1KE3 GRAEGDPGVSWDFYSSSVLEEKDGFACDLLHNPPGSSDQEGDDPMEEDDFMFELSDKPLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GRAEGDPGVSWDFYSSSVLEEKDGFACDLLHNPPGSSDQEGDDPMEEDDFMFELSDKPLL
1630 1640 1650 1660 1670 1680
1610 1620 1630 1640 1650 1660
pF1KE3 PCYNLQVSVSRGPCNWFLFSDVLKRLKLSSRIFQARFPHFEITTMPKAEFYRQVASSQLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PCYNLQVSVSRGPCNWFLFSDVLKRLKLSSRIFQARFPHFEITTMPKAEFYRQVASSQLL
1690 1700 1710 1720 1730 1740
1670 1680 1690 1700 1710
pF1KE3 TPAERPGGLDDRSPPGSSETVELVRYEPDLLRLLGSEVEFQSCNS
:::
XP_016 TPAERPGGLDDRSPPGSSETVELVRYEPDLLRLLGSEVEFQSCNS
1750 1760 1770 1780
>>XP_005262509 (OMIM: 300688) PREDICTED: BCL-6 corepress (1785 aa)
initn: 9684 init1: 9684 opt: 9684 Z-score: 3136.2 bits: 593.4 E(85289): 6e-168
Smith-Waterman score: 11129; 95.8% identity (95.8% similar) in 1743 aa overlap (1-1669:1-1743)
10 20 30 40 50 60
pF1KE3 MISTAPLYSGVHNWTSSDRIRMCGINEERRAPLSDEESTTGDCQHFGSQEFCVSSSFSKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MISTAPLYSGVHNWTSSDRIRMCGINEERRAPLSDEESTTGDCQHFGSQEFCVSSSFSKV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 ELTAVGSGSNARGADPDGSATEKLGHKSEDKPDDPQPKMDYAGNVAEAEGLLVPLSSPGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ELTAVGSGSNARGADPDGSATEKLGHKSEDKPDDPQPKMDYAGNVAEAEGLLVPLSSPGD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 GLKLPASDSAEASNSRADCSWTPLNTQMSKQVDCSPAGVKALDSRQGVGEKNTFILATLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GLKLPASDSAEASNSRADCSWTPLNTQMSKQVDCSPAGVKALDSRQGVGEKNTFILATLG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 TGVPVEGTLPLVTTNFSPLPAPICPPAPGSASVPHSVPDAFQVPLSVPAPVPHSGLVPVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TGVPVEGTLPLVTTNFSPLPAPICPPAPGSASVPHSVPDAFQVPLSVPAPVPHSGLVPVQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 VATSVPAPSPPLAPVPALAPAPPSVPTLISDSNPLSVSASVLVPVPASAPPSGPVPLSAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VATSVPAPSPPLAPVPALAPAPPSVPTLISDSNPLSVSASVLVPVPASAPPSGPVPLSAP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 APAPLSVPVSAPPLALIQAPVPPSAPTLVLAPVPTPVLAPMPASTPPAAPAPPSVPMPTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 APAPLSVPVSAPPLALIQAPVPPSAPTLVLAPVPTPVLAPMPASTPPAAPAPPSVPMPTP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 TPSSGPPSTPTLIPAFAPTPVPAPTPAPIFTPAPTPMPAATPAAIPTSAPIPASFSLSRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TPSSGPPSTPTLIPAFAPTPVPAPTPAPIFTPAPTPMPAATPAAIPTSAPIPASFSLSRV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 CFPAAQAPAMQKVPLSFQPGTVLTPSQPLVYIPPPSCGQPLSVATLPTTLGVSSTLTLPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CFPAAQAPAMQKVPLSFQPGTVLTPSQPLVYIPPPSCGQPLSVATLPTTLGVSSTLTLPV
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 LPSYLQDRCLPGVLASPELRSYPYAFSVARPLTSDSKLVSLEVNRLPCTSPSGSTTTQPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LPSYLQDRCLPGVLASPELRSYPYAFSVARPLTSDSKLVSLEVNRLPCTSPSGSTTTQPA
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 PDGVPGPLADTSLVTASAKVLPTPQPLLPAPSGSSAPPHPAKMPSGTEQQTEGTSVTFSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PDGVPGPLADTSLVTASAKVLPTPQPLLPAPSGSSAPPHPAKMPSGTEQQTEGTSVTFSP
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 LKSPPQLEREMASPPECSEMPLDLSSKSNRQKLPLPNQRKTPPMPVLTPVHTSSKALLST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LKSPPQLEREMASPPECSEMPLDLSSKSNRQKLPLPNQRKTPPMPVLTPVHTSSKALLST
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 VLSRSQRTTQAAGGNVTSCLGSTSSPFVIFPEIVRNGDPSTWVKNSTALISTIPGTYVGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VLSRSQRTTQAAGGNVTSCLGSTSSPFVIFPEIVRNGDPSTWVKNSTALISTIPGTYVGV
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 ANPVPASLLLNKDPNLGLNRDPRHLPKQEPISIIDQGEPKGTGATCGKKGSQAGAEGQPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ANPVPASLLLNKDPNLGLNRDPRHLPKQEPISIIDQGEPKGTGATCGKKGSQAGAEGQPS
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE3 TVKRYTPARIAPGLPGCQTKELSLWKPTGPANIYPRCSVNGKPTSTQVLPVGWSPYHQAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TVKRYTPARIAPGLPGCQTKELSLWKPTGPANIYPRCSVNGKPTSTQVLPVGWSPYHQAS
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE3 LLSIGISSAGQLTPSQGAPIRPTSVVSEFSGVPSLSSSEAVHGLPEGQPRPGGSFVPEQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LLSIGISSAGQLTPSQGAPIRPTSVVSEFSGVPSLSSSEAVHGLPEGQPRPGGSFVPEQD
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE3 PVTKNKTCRIAAKPYEEQVNPVLLTLSPQTGTLALSVQPSGGDIRMNQGPEESESHLCSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PVTKNKTCRIAAKPYEEQVNPVLLTLSPQTGTLALSVQPSGGDIRMNQGPEESESHLCSD
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE3 STPKMEGPQGACGLKLAGDTKPKNQVLATYMSHELVLATPQNLPKMPELPLLPHDSHPKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 STPKMEGPQGACGLKLAGDTKPKNQVLATYMSHELVLATPQNLPKMPELPLLPHDSHPKE
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE3 LILDVVPSSRRGSSTERPQLGSQVDLGRVKMEKVDGDVVFNLATCFRADGLPVAPQRGQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LILDVVPSSRRGSSTERPQLGSQVDLGRVKMEKVDGDVVFNLATCFRADGLPVAPQRGQA
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE3 EVRAKAGQARVKQESVGVFACKNKWQPDDVTESLPPKKMKCGKEKDSEEQQLQPQAKAVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EVRAKAGQARVKQESVGVFACKNKWQPDDVTESLPPKKMKCGKEKDSEEQQLQPQAKAVV
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE3 RSSHRPKCRKLPSDPQESTKKSPRGASDSGKEHNGVRGKHKHRKPTKPESQSPGKRADSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RSSHRPKCRKLPSDPQESTKKSPRGASDSGKEHNGVRGKHKHRKPTKPESQSPGKRADSH
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE3 EEGSLEKKAKSSFRDFIPVVLSTRTRSQSGSICSSFAGMADSDMGSQEVFPTEEEEEVTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EEGSLEKKAKSSFRDFIPVVLSTRTRSQSGSICSSFAGMADSDMGSQEVFPTEEEEEVTP
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE3 TPAKRRKVRKTQRDTQYRSHHAQDKSLLSQGRRHLWRAREMPWRTEAARQMWDTNEEEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TPAKRRKVRKTQRDTQYRSHHAQDKSLLSQGRRHLWRAREMPWRTEAARQMWDTNEEEEE
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE3 EEEEGLLKRKKRRRQKSRKYQTGEYLTEQEDEQRRKGRADLKARKQKTSSSQSLEHRLRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EEEEGLLKRKKRRRQKSRKYQTGEYLTEQEDEQRRKGRADLKARKQKTSSSQSLEHRLRN
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430
pF1KE3 RNLLLPNKVQGISDSPNGFLPNNLEEPACLENSEKPSGKRKCKTKHMATVSEEAK-----
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RNLLLPNKVQGISDSPNGFLPNNLEEPACLENSEKPSGKRKCKTKHMATVSEEAKGKGRW
1390 1400 1410 1420 1430 1440
pF1KE3 ------------------------------------------------------------
XP_005 SQQKTRSPKSPTPVKPTEPCTPSKSRSASSEEASESPTARQIPPEARRLIVNKNAGETLL
1450 1460 1470 1480 1490 1500
1440 1450 1460 1470 1480
pF1KE3 ---------DVVLYCLQKDSEDVNHRDNAGYTALHEACSRGWTDILNILLEHGANVNCSA
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QRAARLGYKDVVLYCLQKDSEDVNHRDNAGYTALHEACSRGWTDILNILLEHGANVNCSA
1510 1520 1530 1540 1550 1560
1490 1500 1510 1520 1530 1540
pF1KE3 QDGTRPVHDAVVNDNLETIWLLLSYGADPTLATYSGQTAMKLASSDTMKRFLSDHLSDLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QDGTRPVHDAVVNDNLETIWLLLSYGADPTLATYSGQTAMKLASSDTMKRFLSDHLSDLQ
1570 1580 1590 1600 1610 1620
1550 1560 1570 1580 1590 1600
pF1KE3 GRAEGDPGVSWDFYSSSVLEEKDGFACDLLHNPPGSSDQEGDDPMEEDDFMFELSDKPLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GRAEGDPGVSWDFYSSSVLEEKDGFACDLLHNPPGSSDQEGDDPMEEDDFMFELSDKPLL
1630 1640 1650 1660 1670 1680
1610 1620 1630 1640 1650 1660
pF1KE3 PCYNLQVSVSRGPCNWFLFSDVLKRLKLSSRIFQARFPHFEITTMPKAEFYRQVASSQLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PCYNLQVSVSRGPCNWFLFSDVLKRLKLSSRIFQARFPHFEITTMPKAEFYRQVASSQLL
1690 1700 1710 1720 1730 1740
1670 1680 1690 1700 1710
pF1KE3 TPAERPGGLDDRSPPGSSETVELVRYEPDLLRLLGSEVEFQSCNS
:::
XP_005 TPAERPGGLDDRSPPGSSETVELVRYEPDLLRLLGSEVEFQSCNS
1750 1760 1770 1780
>>XP_006724839 (OMIM: 300688) PREDICTED: BCL-6 corepress (1785 aa)
initn: 9684 init1: 9684 opt: 9684 Z-score: 3136.2 bits: 593.4 E(85289): 6e-168
Smith-Waterman score: 11129; 95.8% identity (95.8% similar) in 1743 aa overlap (1-1669:1-1743)
10 20 30 40 50 60
pF1KE3 MISTAPLYSGVHNWTSSDRIRMCGINEERRAPLSDEESTTGDCQHFGSQEFCVSSSFSKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MISTAPLYSGVHNWTSSDRIRMCGINEERRAPLSDEESTTGDCQHFGSQEFCVSSSFSKV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 ELTAVGSGSNARGADPDGSATEKLGHKSEDKPDDPQPKMDYAGNVAEAEGLLVPLSSPGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ELTAVGSGSNARGADPDGSATEKLGHKSEDKPDDPQPKMDYAGNVAEAEGLLVPLSSPGD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 GLKLPASDSAEASNSRADCSWTPLNTQMSKQVDCSPAGVKALDSRQGVGEKNTFILATLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GLKLPASDSAEASNSRADCSWTPLNTQMSKQVDCSPAGVKALDSRQGVGEKNTFILATLG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 TGVPVEGTLPLVTTNFSPLPAPICPPAPGSASVPHSVPDAFQVPLSVPAPVPHSGLVPVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TGVPVEGTLPLVTTNFSPLPAPICPPAPGSASVPHSVPDAFQVPLSVPAPVPHSGLVPVQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 VATSVPAPSPPLAPVPALAPAPPSVPTLISDSNPLSVSASVLVPVPASAPPSGPVPLSAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VATSVPAPSPPLAPVPALAPAPPSVPTLISDSNPLSVSASVLVPVPASAPPSGPVPLSAP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 APAPLSVPVSAPPLALIQAPVPPSAPTLVLAPVPTPVLAPMPASTPPAAPAPPSVPMPTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 APAPLSVPVSAPPLALIQAPVPPSAPTLVLAPVPTPVLAPMPASTPPAAPAPPSVPMPTP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 TPSSGPPSTPTLIPAFAPTPVPAPTPAPIFTPAPTPMPAATPAAIPTSAPIPASFSLSRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TPSSGPPSTPTLIPAFAPTPVPAPTPAPIFTPAPTPMPAATPAAIPTSAPIPASFSLSRV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 CFPAAQAPAMQKVPLSFQPGTVLTPSQPLVYIPPPSCGQPLSVATLPTTLGVSSTLTLPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 CFPAAQAPAMQKVPLSFQPGTVLTPSQPLVYIPPPSCGQPLSVATLPTTLGVSSTLTLPV
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 LPSYLQDRCLPGVLASPELRSYPYAFSVARPLTSDSKLVSLEVNRLPCTSPSGSTTTQPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LPSYLQDRCLPGVLASPELRSYPYAFSVARPLTSDSKLVSLEVNRLPCTSPSGSTTTQPA
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 PDGVPGPLADTSLVTASAKVLPTPQPLLPAPSGSSAPPHPAKMPSGTEQQTEGTSVTFSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PDGVPGPLADTSLVTASAKVLPTPQPLLPAPSGSSAPPHPAKMPSGTEQQTEGTSVTFSP
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 LKSPPQLEREMASPPECSEMPLDLSSKSNRQKLPLPNQRKTPPMPVLTPVHTSSKALLST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LKSPPQLEREMASPPECSEMPLDLSSKSNRQKLPLPNQRKTPPMPVLTPVHTSSKALLST
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 VLSRSQRTTQAAGGNVTSCLGSTSSPFVIFPEIVRNGDPSTWVKNSTALISTIPGTYVGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VLSRSQRTTQAAGGNVTSCLGSTSSPFVIFPEIVRNGDPSTWVKNSTALISTIPGTYVGV
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 ANPVPASLLLNKDPNLGLNRDPRHLPKQEPISIIDQGEPKGTGATCGKKGSQAGAEGQPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ANPVPASLLLNKDPNLGLNRDPRHLPKQEPISIIDQGEPKGTGATCGKKGSQAGAEGQPS
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE3 TVKRYTPARIAPGLPGCQTKELSLWKPTGPANIYPRCSVNGKPTSTQVLPVGWSPYHQAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TVKRYTPARIAPGLPGCQTKELSLWKPTGPANIYPRCSVNGKPTSTQVLPVGWSPYHQAS
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE3 LLSIGISSAGQLTPSQGAPIRPTSVVSEFSGVPSLSSSEAVHGLPEGQPRPGGSFVPEQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LLSIGISSAGQLTPSQGAPIRPTSVVSEFSGVPSLSSSEAVHGLPEGQPRPGGSFVPEQD
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE3 PVTKNKTCRIAAKPYEEQVNPVLLTLSPQTGTLALSVQPSGGDIRMNQGPEESESHLCSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PVTKNKTCRIAAKPYEEQVNPVLLTLSPQTGTLALSVQPSGGDIRMNQGPEESESHLCSD
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE3 STPKMEGPQGACGLKLAGDTKPKNQVLATYMSHELVLATPQNLPKMPELPLLPHDSHPKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 STPKMEGPQGACGLKLAGDTKPKNQVLATYMSHELVLATPQNLPKMPELPLLPHDSHPKE
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE3 LILDVVPSSRRGSSTERPQLGSQVDLGRVKMEKVDGDVVFNLATCFRADGLPVAPQRGQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LILDVVPSSRRGSSTERPQLGSQVDLGRVKMEKVDGDVVFNLATCFRADGLPVAPQRGQA
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE3 EVRAKAGQARVKQESVGVFACKNKWQPDDVTESLPPKKMKCGKEKDSEEQQLQPQAKAVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EVRAKAGQARVKQESVGVFACKNKWQPDDVTESLPPKKMKCGKEKDSEEQQLQPQAKAVV
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE3 RSSHRPKCRKLPSDPQESTKKSPRGASDSGKEHNGVRGKHKHRKPTKPESQSPGKRADSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RSSHRPKCRKLPSDPQESTKKSPRGASDSGKEHNGVRGKHKHRKPTKPESQSPGKRADSH
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE3 EEGSLEKKAKSSFRDFIPVVLSTRTRSQSGSICSSFAGMADSDMGSQEVFPTEEEEEVTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EEGSLEKKAKSSFRDFIPVVLSTRTRSQSGSICSSFAGMADSDMGSQEVFPTEEEEEVTP
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE3 TPAKRRKVRKTQRDTQYRSHHAQDKSLLSQGRRHLWRAREMPWRTEAARQMWDTNEEEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TPAKRRKVRKTQRDTQYRSHHAQDKSLLSQGRRHLWRAREMPWRTEAARQMWDTNEEEEE
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE3 EEEEGLLKRKKRRRQKSRKYQTGEYLTEQEDEQRRKGRADLKARKQKTSSSQSLEHRLRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EEEEGLLKRKKRRRQKSRKYQTGEYLTEQEDEQRRKGRADLKARKQKTSSSQSLEHRLRN
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430
pF1KE3 RNLLLPNKVQGISDSPNGFLPNNLEEPACLENSEKPSGKRKCKTKHMATVSEEAK-----
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RNLLLPNKVQGISDSPNGFLPNNLEEPACLENSEKPSGKRKCKTKHMATVSEEAKGKGRW
1390 1400 1410 1420 1430 1440
pF1KE3 ------------------------------------------------------------
XP_006 SQQKTRSPKSPTPVKPTEPCTPSKSRSASSEEASESPTARQIPPEARRLIVNKNAGETLL
1450 1460 1470 1480 1490 1500
1440 1450 1460 1470 1480
pF1KE3 ---------DVVLYCLQKDSEDVNHRDNAGYTALHEACSRGWTDILNILLEHGANVNCSA
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QRAARLGYKDVVLYCLQKDSEDVNHRDNAGYTALHEACSRGWTDILNILLEHGANVNCSA
1510 1520 1530 1540 1550 1560
1490 1500 1510 1520 1530 1540
pF1KE3 QDGTRPVHDAVVNDNLETIWLLLSYGADPTLATYSGQTAMKLASSDTMKRFLSDHLSDLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QDGTRPVHDAVVNDNLETIWLLLSYGADPTLATYSGQTAMKLASSDTMKRFLSDHLSDLQ
1570 1580 1590 1600 1610 1620
1550 1560 1570 1580 1590 1600
pF1KE3 GRAEGDPGVSWDFYSSSVLEEKDGFACDLLHNPPGSSDQEGDDPMEEDDFMFELSDKPLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GRAEGDPGVSWDFYSSSVLEEKDGFACDLLHNPPGSSDQEGDDPMEEDDFMFELSDKPLL
1630 1640 1650 1660 1670 1680
1610 1620 1630 1640 1650 1660
pF1KE3 PCYNLQVSVSRGPCNWFLFSDVLKRLKLSSRIFQARFPHFEITTMPKAEFYRQVASSQLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PCYNLQVSVSRGPCNWFLFSDVLKRLKLSSRIFQARFPHFEITTMPKAEFYRQVASSQLL
1690 1700 1710 1720 1730 1740
1670 1680 1690 1700 1710
pF1KE3 TPAERPGGLDDRSPPGSSETVELVRYEPDLLRLLGSEVEFQSCNS
:::
XP_006 TPAERPGGLDDRSPPGSSETVELVRYEPDLLRLLGSEVEFQSCNS
1750 1760 1770 1780
>>XP_005262510 (OMIM: 300688) PREDICTED: BCL-6 corepress (1785 aa)
initn: 9684 init1: 9684 opt: 9684 Z-score: 3136.2 bits: 593.4 E(85289): 6e-168
Smith-Waterman score: 11129; 95.8% identity (95.8% similar) in 1743 aa overlap (1-1669:1-1743)
10 20 30 40 50 60
pF1KE3 MISTAPLYSGVHNWTSSDRIRMCGINEERRAPLSDEESTTGDCQHFGSQEFCVSSSFSKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MISTAPLYSGVHNWTSSDRIRMCGINEERRAPLSDEESTTGDCQHFGSQEFCVSSSFSKV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 ELTAVGSGSNARGADPDGSATEKLGHKSEDKPDDPQPKMDYAGNVAEAEGLLVPLSSPGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ELTAVGSGSNARGADPDGSATEKLGHKSEDKPDDPQPKMDYAGNVAEAEGLLVPLSSPGD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 GLKLPASDSAEASNSRADCSWTPLNTQMSKQVDCSPAGVKALDSRQGVGEKNTFILATLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GLKLPASDSAEASNSRADCSWTPLNTQMSKQVDCSPAGVKALDSRQGVGEKNTFILATLG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 TGVPVEGTLPLVTTNFSPLPAPICPPAPGSASVPHSVPDAFQVPLSVPAPVPHSGLVPVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TGVPVEGTLPLVTTNFSPLPAPICPPAPGSASVPHSVPDAFQVPLSVPAPVPHSGLVPVQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 VATSVPAPSPPLAPVPALAPAPPSVPTLISDSNPLSVSASVLVPVPASAPPSGPVPLSAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VATSVPAPSPPLAPVPALAPAPPSVPTLISDSNPLSVSASVLVPVPASAPPSGPVPLSAP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 APAPLSVPVSAPPLALIQAPVPPSAPTLVLAPVPTPVLAPMPASTPPAAPAPPSVPMPTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 APAPLSVPVSAPPLALIQAPVPPSAPTLVLAPVPTPVLAPMPASTPPAAPAPPSVPMPTP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 TPSSGPPSTPTLIPAFAPTPVPAPTPAPIFTPAPTPMPAATPAAIPTSAPIPASFSLSRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TPSSGPPSTPTLIPAFAPTPVPAPTPAPIFTPAPTPMPAATPAAIPTSAPIPASFSLSRV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 CFPAAQAPAMQKVPLSFQPGTVLTPSQPLVYIPPPSCGQPLSVATLPTTLGVSSTLTLPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CFPAAQAPAMQKVPLSFQPGTVLTPSQPLVYIPPPSCGQPLSVATLPTTLGVSSTLTLPV
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 LPSYLQDRCLPGVLASPELRSYPYAFSVARPLTSDSKLVSLEVNRLPCTSPSGSTTTQPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LPSYLQDRCLPGVLASPELRSYPYAFSVARPLTSDSKLVSLEVNRLPCTSPSGSTTTQPA
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 PDGVPGPLADTSLVTASAKVLPTPQPLLPAPSGSSAPPHPAKMPSGTEQQTEGTSVTFSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PDGVPGPLADTSLVTASAKVLPTPQPLLPAPSGSSAPPHPAKMPSGTEQQTEGTSVTFSP
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 LKSPPQLEREMASPPECSEMPLDLSSKSNRQKLPLPNQRKTPPMPVLTPVHTSSKALLST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LKSPPQLEREMASPPECSEMPLDLSSKSNRQKLPLPNQRKTPPMPVLTPVHTSSKALLST
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 VLSRSQRTTQAAGGNVTSCLGSTSSPFVIFPEIVRNGDPSTWVKNSTALISTIPGTYVGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VLSRSQRTTQAAGGNVTSCLGSTSSPFVIFPEIVRNGDPSTWVKNSTALISTIPGTYVGV
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 ANPVPASLLLNKDPNLGLNRDPRHLPKQEPISIIDQGEPKGTGATCGKKGSQAGAEGQPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ANPVPASLLLNKDPNLGLNRDPRHLPKQEPISIIDQGEPKGTGATCGKKGSQAGAEGQPS
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE3 TVKRYTPARIAPGLPGCQTKELSLWKPTGPANIYPRCSVNGKPTSTQVLPVGWSPYHQAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TVKRYTPARIAPGLPGCQTKELSLWKPTGPANIYPRCSVNGKPTSTQVLPVGWSPYHQAS
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE3 LLSIGISSAGQLTPSQGAPIRPTSVVSEFSGVPSLSSSEAVHGLPEGQPRPGGSFVPEQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LLSIGISSAGQLTPSQGAPIRPTSVVSEFSGVPSLSSSEAVHGLPEGQPRPGGSFVPEQD
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE3 PVTKNKTCRIAAKPYEEQVNPVLLTLSPQTGTLALSVQPSGGDIRMNQGPEESESHLCSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PVTKNKTCRIAAKPYEEQVNPVLLTLSPQTGTLALSVQPSGGDIRMNQGPEESESHLCSD
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE3 STPKMEGPQGACGLKLAGDTKPKNQVLATYMSHELVLATPQNLPKMPELPLLPHDSHPKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 STPKMEGPQGACGLKLAGDTKPKNQVLATYMSHELVLATPQNLPKMPELPLLPHDSHPKE
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE3 LILDVVPSSRRGSSTERPQLGSQVDLGRVKMEKVDGDVVFNLATCFRADGLPVAPQRGQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LILDVVPSSRRGSSTERPQLGSQVDLGRVKMEKVDGDVVFNLATCFRADGLPVAPQRGQA
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE3 EVRAKAGQARVKQESVGVFACKNKWQPDDVTESLPPKKMKCGKEKDSEEQQLQPQAKAVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EVRAKAGQARVKQESVGVFACKNKWQPDDVTESLPPKKMKCGKEKDSEEQQLQPQAKAVV
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE3 RSSHRPKCRKLPSDPQESTKKSPRGASDSGKEHNGVRGKHKHRKPTKPESQSPGKRADSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RSSHRPKCRKLPSDPQESTKKSPRGASDSGKEHNGVRGKHKHRKPTKPESQSPGKRADSH
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE3 EEGSLEKKAKSSFRDFIPVVLSTRTRSQSGSICSSFAGMADSDMGSQEVFPTEEEEEVTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EEGSLEKKAKSSFRDFIPVVLSTRTRSQSGSICSSFAGMADSDMGSQEVFPTEEEEEVTP
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE3 TPAKRRKVRKTQRDTQYRSHHAQDKSLLSQGRRHLWRAREMPWRTEAARQMWDTNEEEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TPAKRRKVRKTQRDTQYRSHHAQDKSLLSQGRRHLWRAREMPWRTEAARQMWDTNEEEEE
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE3 EEEEGLLKRKKRRRQKSRKYQTGEYLTEQEDEQRRKGRADLKARKQKTSSSQSLEHRLRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EEEEGLLKRKKRRRQKSRKYQTGEYLTEQEDEQRRKGRADLKARKQKTSSSQSLEHRLRN
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430
pF1KE3 RNLLLPNKVQGISDSPNGFLPNNLEEPACLENSEKPSGKRKCKTKHMATVSEEAK-----
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RNLLLPNKVQGISDSPNGFLPNNLEEPACLENSEKPSGKRKCKTKHMATVSEEAKGKGRW
1390 1400 1410 1420 1430 1440
pF1KE3 ------------------------------------------------------------
XP_005 SQQKTRSPKSPTPVKPTEPCTPSKSRSASSEEASESPTARQIPPEARRLIVNKNAGETLL
1450 1460 1470 1480 1490 1500
1440 1450 1460 1470 1480
pF1KE3 ---------DVVLYCLQKDSEDVNHRDNAGYTALHEACSRGWTDILNILLEHGANVNCSA
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QRAARLGYKDVVLYCLQKDSEDVNHRDNAGYTALHEACSRGWTDILNILLEHGANVNCSA
1510 1520 1530 1540 1550 1560
1490 1500 1510 1520 1530 1540
pF1KE3 QDGTRPVHDAVVNDNLETIWLLLSYGADPTLATYSGQTAMKLASSDTMKRFLSDHLSDLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QDGTRPVHDAVVNDNLETIWLLLSYGADPTLATYSGQTAMKLASSDTMKRFLSDHLSDLQ
1570 1580 1590 1600 1610 1620
1550 1560 1570 1580 1590 1600
pF1KE3 GRAEGDPGVSWDFYSSSVLEEKDGFACDLLHNPPGSSDQEGDDPMEEDDFMFELSDKPLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GRAEGDPGVSWDFYSSSVLEEKDGFACDLLHNPPGSSDQEGDDPMEEDDFMFELSDKPLL
1630 1640 1650 1660 1670 1680
1610 1620 1630 1640 1650 1660
pF1KE3 PCYNLQVSVSRGPCNWFLFSDVLKRLKLSSRIFQARFPHFEITTMPKAEFYRQVASSQLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PCYNLQVSVSRGPCNWFLFSDVLKRLKLSSRIFQARFPHFEITTMPKAEFYRQVASSQLL
1690 1700 1710 1720 1730 1740
1670 1680 1690 1700 1710
pF1KE3 TPAERPGGLDDRSPPGSSETVELVRYEPDLLRLLGSEVEFQSCNS
:::
XP_005 TPAERPGGLDDRSPPGSSETVELVRYEPDLLRLLGSEVEFQSCNS
1750 1760 1770 1780
>>XP_006724840 (OMIM: 300688) PREDICTED: BCL-6 corepress (1785 aa)
initn: 9684 init1: 9684 opt: 9684 Z-score: 3136.2 bits: 593.4 E(85289): 6e-168
Smith-Waterman score: 11129; 95.8% identity (95.8% similar) in 1743 aa overlap (1-1669:1-1743)
10 20 30 40 50 60
pF1KE3 MISTAPLYSGVHNWTSSDRIRMCGINEERRAPLSDEESTTGDCQHFGSQEFCVSSSFSKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MISTAPLYSGVHNWTSSDRIRMCGINEERRAPLSDEESTTGDCQHFGSQEFCVSSSFSKV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 ELTAVGSGSNARGADPDGSATEKLGHKSEDKPDDPQPKMDYAGNVAEAEGLLVPLSSPGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ELTAVGSGSNARGADPDGSATEKLGHKSEDKPDDPQPKMDYAGNVAEAEGLLVPLSSPGD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 GLKLPASDSAEASNSRADCSWTPLNTQMSKQVDCSPAGVKALDSRQGVGEKNTFILATLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GLKLPASDSAEASNSRADCSWTPLNTQMSKQVDCSPAGVKALDSRQGVGEKNTFILATLG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 TGVPVEGTLPLVTTNFSPLPAPICPPAPGSASVPHSVPDAFQVPLSVPAPVPHSGLVPVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TGVPVEGTLPLVTTNFSPLPAPICPPAPGSASVPHSVPDAFQVPLSVPAPVPHSGLVPVQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 VATSVPAPSPPLAPVPALAPAPPSVPTLISDSNPLSVSASVLVPVPASAPPSGPVPLSAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VATSVPAPSPPLAPVPALAPAPPSVPTLISDSNPLSVSASVLVPVPASAPPSGPVPLSAP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 APAPLSVPVSAPPLALIQAPVPPSAPTLVLAPVPTPVLAPMPASTPPAAPAPPSVPMPTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 APAPLSVPVSAPPLALIQAPVPPSAPTLVLAPVPTPVLAPMPASTPPAAPAPPSVPMPTP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 TPSSGPPSTPTLIPAFAPTPVPAPTPAPIFTPAPTPMPAATPAAIPTSAPIPASFSLSRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TPSSGPPSTPTLIPAFAPTPVPAPTPAPIFTPAPTPMPAATPAAIPTSAPIPASFSLSRV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 CFPAAQAPAMQKVPLSFQPGTVLTPSQPLVYIPPPSCGQPLSVATLPTTLGVSSTLTLPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 CFPAAQAPAMQKVPLSFQPGTVLTPSQPLVYIPPPSCGQPLSVATLPTTLGVSSTLTLPV
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 LPSYLQDRCLPGVLASPELRSYPYAFSVARPLTSDSKLVSLEVNRLPCTSPSGSTTTQPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LPSYLQDRCLPGVLASPELRSYPYAFSVARPLTSDSKLVSLEVNRLPCTSPSGSTTTQPA
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 PDGVPGPLADTSLVTASAKVLPTPQPLLPAPSGSSAPPHPAKMPSGTEQQTEGTSVTFSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PDGVPGPLADTSLVTASAKVLPTPQPLLPAPSGSSAPPHPAKMPSGTEQQTEGTSVTFSP
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 LKSPPQLEREMASPPECSEMPLDLSSKSNRQKLPLPNQRKTPPMPVLTPVHTSSKALLST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LKSPPQLEREMASPPECSEMPLDLSSKSNRQKLPLPNQRKTPPMPVLTPVHTSSKALLST
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 VLSRSQRTTQAAGGNVTSCLGSTSSPFVIFPEIVRNGDPSTWVKNSTALISTIPGTYVGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VLSRSQRTTQAAGGNVTSCLGSTSSPFVIFPEIVRNGDPSTWVKNSTALISTIPGTYVGV
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 ANPVPASLLLNKDPNLGLNRDPRHLPKQEPISIIDQGEPKGTGATCGKKGSQAGAEGQPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ANPVPASLLLNKDPNLGLNRDPRHLPKQEPISIIDQGEPKGTGATCGKKGSQAGAEGQPS
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE3 TVKRYTPARIAPGLPGCQTKELSLWKPTGPANIYPRCSVNGKPTSTQVLPVGWSPYHQAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TVKRYTPARIAPGLPGCQTKELSLWKPTGPANIYPRCSVNGKPTSTQVLPVGWSPYHQAS
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE3 LLSIGISSAGQLTPSQGAPIRPTSVVSEFSGVPSLSSSEAVHGLPEGQPRPGGSFVPEQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LLSIGISSAGQLTPSQGAPIRPTSVVSEFSGVPSLSSSEAVHGLPEGQPRPGGSFVPEQD
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE3 PVTKNKTCRIAAKPYEEQVNPVLLTLSPQTGTLALSVQPSGGDIRMNQGPEESESHLCSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PVTKNKTCRIAAKPYEEQVNPVLLTLSPQTGTLALSVQPSGGDIRMNQGPEESESHLCSD
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE3 STPKMEGPQGACGLKLAGDTKPKNQVLATYMSHELVLATPQNLPKMPELPLLPHDSHPKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 STPKMEGPQGACGLKLAGDTKPKNQVLATYMSHELVLATPQNLPKMPELPLLPHDSHPKE
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE3 LILDVVPSSRRGSSTERPQLGSQVDLGRVKMEKVDGDVVFNLATCFRADGLPVAPQRGQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LILDVVPSSRRGSSTERPQLGSQVDLGRVKMEKVDGDVVFNLATCFRADGLPVAPQRGQA
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE3 EVRAKAGQARVKQESVGVFACKNKWQPDDVTESLPPKKMKCGKEKDSEEQQLQPQAKAVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EVRAKAGQARVKQESVGVFACKNKWQPDDVTESLPPKKMKCGKEKDSEEQQLQPQAKAVV
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE3 RSSHRPKCRKLPSDPQESTKKSPRGASDSGKEHNGVRGKHKHRKPTKPESQSPGKRADSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RSSHRPKCRKLPSDPQESTKKSPRGASDSGKEHNGVRGKHKHRKPTKPESQSPGKRADSH
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE3 EEGSLEKKAKSSFRDFIPVVLSTRTRSQSGSICSSFAGMADSDMGSQEVFPTEEEEEVTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EEGSLEKKAKSSFRDFIPVVLSTRTRSQSGSICSSFAGMADSDMGSQEVFPTEEEEEVTP
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE3 TPAKRRKVRKTQRDTQYRSHHAQDKSLLSQGRRHLWRAREMPWRTEAARQMWDTNEEEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TPAKRRKVRKTQRDTQYRSHHAQDKSLLSQGRRHLWRAREMPWRTEAARQMWDTNEEEEE
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE3 EEEEGLLKRKKRRRQKSRKYQTGEYLTEQEDEQRRKGRADLKARKQKTSSSQSLEHRLRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EEEEGLLKRKKRRRQKSRKYQTGEYLTEQEDEQRRKGRADLKARKQKTSSSQSLEHRLRN
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430
pF1KE3 RNLLLPNKVQGISDSPNGFLPNNLEEPACLENSEKPSGKRKCKTKHMATVSEEAK-----
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RNLLLPNKVQGISDSPNGFLPNNLEEPACLENSEKPSGKRKCKTKHMATVSEEAKGKGRW
1390 1400 1410 1420 1430 1440
pF1KE3 ------------------------------------------------------------
XP_006 SQQKTRSPKSPTPVKPTEPCTPSKSRSASSEEASESPTARQIPPEARRLIVNKNAGETLL
1450 1460 1470 1480 1490 1500
1440 1450 1460 1470 1480
pF1KE3 ---------DVVLYCLQKDSEDVNHRDNAGYTALHEACSRGWTDILNILLEHGANVNCSA
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QRAARLGYKDVVLYCLQKDSEDVNHRDNAGYTALHEACSRGWTDILNILLEHGANVNCSA
1510 1520 1530 1540 1550 1560
1490 1500 1510 1520 1530 1540
pF1KE3 QDGTRPVHDAVVNDNLETIWLLLSYGADPTLATYSGQTAMKLASSDTMKRFLSDHLSDLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QDGTRPVHDAVVNDNLETIWLLLSYGADPTLATYSGQTAMKLASSDTMKRFLSDHLSDLQ
1570 1580 1590 1600 1610 1620
1550 1560 1570 1580 1590 1600
pF1KE3 GRAEGDPGVSWDFYSSSVLEEKDGFACDLLHNPPGSSDQEGDDPMEEDDFMFELSDKPLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GRAEGDPGVSWDFYSSSVLEEKDGFACDLLHNPPGSSDQEGDDPMEEDDFMFELSDKPLL
1630 1640 1650 1660 1670 1680
1610 1620 1630 1640 1650 1660
pF1KE3 PCYNLQVSVSRGPCNWFLFSDVLKRLKLSSRIFQARFPHFEITTMPKAEFYRQVASSQLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PCYNLQVSVSRGPCNWFLFSDVLKRLKLSSRIFQARFPHFEITTMPKAEFYRQVASSQLL
1690 1700 1710 1720 1730 1740
1670 1680 1690 1700 1710
pF1KE3 TPAERPGGLDDRSPPGSSETVELVRYEPDLLRLLGSEVEFQSCNS
:::
XP_006 TPAERPGGLDDRSPPGSSETVELVRYEPDLLRLLGSEVEFQSCNS
1750 1760 1770 1780
>>XP_016885210 (OMIM: 300688) PREDICTED: BCL-6 corepress (1785 aa)
initn: 9684 init1: 9684 opt: 9684 Z-score: 3136.2 bits: 593.4 E(85289): 6e-168
Smith-Waterman score: 11129; 95.8% identity (95.8% similar) in 1743 aa overlap (1-1669:1-1743)
10 20 30 40 50 60
pF1KE3 MISTAPLYSGVHNWTSSDRIRMCGINEERRAPLSDEESTTGDCQHFGSQEFCVSSSFSKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MISTAPLYSGVHNWTSSDRIRMCGINEERRAPLSDEESTTGDCQHFGSQEFCVSSSFSKV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 ELTAVGSGSNARGADPDGSATEKLGHKSEDKPDDPQPKMDYAGNVAEAEGLLVPLSSPGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELTAVGSGSNARGADPDGSATEKLGHKSEDKPDDPQPKMDYAGNVAEAEGLLVPLSSPGD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 GLKLPASDSAEASNSRADCSWTPLNTQMSKQVDCSPAGVKALDSRQGVGEKNTFILATLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLKLPASDSAEASNSRADCSWTPLNTQMSKQVDCSPAGVKALDSRQGVGEKNTFILATLG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 TGVPVEGTLPLVTTNFSPLPAPICPPAPGSASVPHSVPDAFQVPLSVPAPVPHSGLVPVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TGVPVEGTLPLVTTNFSPLPAPICPPAPGSASVPHSVPDAFQVPLSVPAPVPHSGLVPVQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 VATSVPAPSPPLAPVPALAPAPPSVPTLISDSNPLSVSASVLVPVPASAPPSGPVPLSAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VATSVPAPSPPLAPVPALAPAPPSVPTLISDSNPLSVSASVLVPVPASAPPSGPVPLSAP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 APAPLSVPVSAPPLALIQAPVPPSAPTLVLAPVPTPVLAPMPASTPPAAPAPPSVPMPTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 APAPLSVPVSAPPLALIQAPVPPSAPTLVLAPVPTPVLAPMPASTPPAAPAPPSVPMPTP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 TPSSGPPSTPTLIPAFAPTPVPAPTPAPIFTPAPTPMPAATPAAIPTSAPIPASFSLSRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TPSSGPPSTPTLIPAFAPTPVPAPTPAPIFTPAPTPMPAATPAAIPTSAPIPASFSLSRV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 CFPAAQAPAMQKVPLSFQPGTVLTPSQPLVYIPPPSCGQPLSVATLPTTLGVSSTLTLPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CFPAAQAPAMQKVPLSFQPGTVLTPSQPLVYIPPPSCGQPLSVATLPTTLGVSSTLTLPV
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 LPSYLQDRCLPGVLASPELRSYPYAFSVARPLTSDSKLVSLEVNRLPCTSPSGSTTTQPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LPSYLQDRCLPGVLASPELRSYPYAFSVARPLTSDSKLVSLEVNRLPCTSPSGSTTTQPA
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 PDGVPGPLADTSLVTASAKVLPTPQPLLPAPSGSSAPPHPAKMPSGTEQQTEGTSVTFSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PDGVPGPLADTSLVTASAKVLPTPQPLLPAPSGSSAPPHPAKMPSGTEQQTEGTSVTFSP
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 LKSPPQLEREMASPPECSEMPLDLSSKSNRQKLPLPNQRKTPPMPVLTPVHTSSKALLST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKSPPQLEREMASPPECSEMPLDLSSKSNRQKLPLPNQRKTPPMPVLTPVHTSSKALLST
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 VLSRSQRTTQAAGGNVTSCLGSTSSPFVIFPEIVRNGDPSTWVKNSTALISTIPGTYVGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLSRSQRTTQAAGGNVTSCLGSTSSPFVIFPEIVRNGDPSTWVKNSTALISTIPGTYVGV
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 ANPVPASLLLNKDPNLGLNRDPRHLPKQEPISIIDQGEPKGTGATCGKKGSQAGAEGQPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ANPVPASLLLNKDPNLGLNRDPRHLPKQEPISIIDQGEPKGTGATCGKKGSQAGAEGQPS
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE3 TVKRYTPARIAPGLPGCQTKELSLWKPTGPANIYPRCSVNGKPTSTQVLPVGWSPYHQAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TVKRYTPARIAPGLPGCQTKELSLWKPTGPANIYPRCSVNGKPTSTQVLPVGWSPYHQAS
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE3 LLSIGISSAGQLTPSQGAPIRPTSVVSEFSGVPSLSSSEAVHGLPEGQPRPGGSFVPEQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLSIGISSAGQLTPSQGAPIRPTSVVSEFSGVPSLSSSEAVHGLPEGQPRPGGSFVPEQD
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE3 PVTKNKTCRIAAKPYEEQVNPVLLTLSPQTGTLALSVQPSGGDIRMNQGPEESESHLCSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PVTKNKTCRIAAKPYEEQVNPVLLTLSPQTGTLALSVQPSGGDIRMNQGPEESESHLCSD
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE3 STPKMEGPQGACGLKLAGDTKPKNQVLATYMSHELVLATPQNLPKMPELPLLPHDSHPKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 STPKMEGPQGACGLKLAGDTKPKNQVLATYMSHELVLATPQNLPKMPELPLLPHDSHPKE
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE3 LILDVVPSSRRGSSTERPQLGSQVDLGRVKMEKVDGDVVFNLATCFRADGLPVAPQRGQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LILDVVPSSRRGSSTERPQLGSQVDLGRVKMEKVDGDVVFNLATCFRADGLPVAPQRGQA
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE3 EVRAKAGQARVKQESVGVFACKNKWQPDDVTESLPPKKMKCGKEKDSEEQQLQPQAKAVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EVRAKAGQARVKQESVGVFACKNKWQPDDVTESLPPKKMKCGKEKDSEEQQLQPQAKAVV
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE3 RSSHRPKCRKLPSDPQESTKKSPRGASDSGKEHNGVRGKHKHRKPTKPESQSPGKRADSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RSSHRPKCRKLPSDPQESTKKSPRGASDSGKEHNGVRGKHKHRKPTKPESQSPGKRADSH
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE3 EEGSLEKKAKSSFRDFIPVVLSTRTRSQSGSICSSFAGMADSDMGSQEVFPTEEEEEVTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEGSLEKKAKSSFRDFIPVVLSTRTRSQSGSICSSFAGMADSDMGSQEVFPTEEEEEVTP
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE3 TPAKRRKVRKTQRDTQYRSHHAQDKSLLSQGRRHLWRAREMPWRTEAARQMWDTNEEEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TPAKRRKVRKTQRDTQYRSHHAQDKSLLSQGRRHLWRAREMPWRTEAARQMWDTNEEEEE
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE3 EEEEGLLKRKKRRRQKSRKYQTGEYLTEQEDEQRRKGRADLKARKQKTSSSQSLEHRLRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEEEGLLKRKKRRRQKSRKYQTGEYLTEQEDEQRRKGRADLKARKQKTSSSQSLEHRLRN
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430
pF1KE3 RNLLLPNKVQGISDSPNGFLPNNLEEPACLENSEKPSGKRKCKTKHMATVSEEAK-----
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RNLLLPNKVQGISDSPNGFLPNNLEEPACLENSEKPSGKRKCKTKHMATVSEEAKGKGRW
1390 1400 1410 1420 1430 1440
pF1KE3 ------------------------------------------------------------
XP_016 SQQKTRSPKSPTPVKPTEPCTPSKSRSASSEEASESPTARQIPPEARRLIVNKNAGETLL
1450 1460 1470 1480 1490 1500
1440 1450 1460 1470 1480
pF1KE3 ---------DVVLYCLQKDSEDVNHRDNAGYTALHEACSRGWTDILNILLEHGANVNCSA
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QRAARLGYKDVVLYCLQKDSEDVNHRDNAGYTALHEACSRGWTDILNILLEHGANVNCSA
1510 1520 1530 1540 1550 1560
1490 1500 1510 1520 1530 1540
pF1KE3 QDGTRPVHDAVVNDNLETIWLLLSYGADPTLATYSGQTAMKLASSDTMKRFLSDHLSDLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QDGTRPVHDAVVNDNLETIWLLLSYGADPTLATYSGQTAMKLASSDTMKRFLSDHLSDLQ
1570 1580 1590 1600 1610 1620
1550 1560 1570 1580 1590 1600
pF1KE3 GRAEGDPGVSWDFYSSSVLEEKDGFACDLLHNPPGSSDQEGDDPMEEDDFMFELSDKPLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GRAEGDPGVSWDFYSSSVLEEKDGFACDLLHNPPGSSDQEGDDPMEEDDFMFELSDKPLL
1630 1640 1650 1660 1670 1680
1610 1620 1630 1640 1650 1660
pF1KE3 PCYNLQVSVSRGPCNWFLFSDVLKRLKLSSRIFQARFPHFEITTMPKAEFYRQVASSQLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PCYNLQVSVSRGPCNWFLFSDVLKRLKLSSRIFQARFPHFEITTMPKAEFYRQVASSQLL
1690 1700 1710 1720 1730 1740
1670 1680 1690 1700 1710
pF1KE3 TPAERPGGLDDRSPPGSSETVELVRYEPDLLRLLGSEVEFQSCNS
:::
XP_016 TPAERPGGLDDRSPPGSSETVELVRYEPDLLRLLGSEVEFQSCNS
1750 1760 1770 1780
>>NP_001171701 (OMIM: 300688) BCL-6 corepressor-like pro (1785 aa)
initn: 9684 init1: 9684 opt: 9684 Z-score: 3136.2 bits: 593.4 E(85289): 6e-168
Smith-Waterman score: 11129; 95.8% identity (95.8% similar) in 1743 aa overlap (1-1669:1-1743)
10 20 30 40 50 60
pF1KE3 MISTAPLYSGVHNWTSSDRIRMCGINEERRAPLSDEESTTGDCQHFGSQEFCVSSSFSKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MISTAPLYSGVHNWTSSDRIRMCGINEERRAPLSDEESTTGDCQHFGSQEFCVSSSFSKV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 ELTAVGSGSNARGADPDGSATEKLGHKSEDKPDDPQPKMDYAGNVAEAEGLLVPLSSPGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELTAVGSGSNARGADPDGSATEKLGHKSEDKPDDPQPKMDYAGNVAEAEGLLVPLSSPGD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 GLKLPASDSAEASNSRADCSWTPLNTQMSKQVDCSPAGVKALDSRQGVGEKNTFILATLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GLKLPASDSAEASNSRADCSWTPLNTQMSKQVDCSPAGVKALDSRQGVGEKNTFILATLG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 TGVPVEGTLPLVTTNFSPLPAPICPPAPGSASVPHSVPDAFQVPLSVPAPVPHSGLVPVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TGVPVEGTLPLVTTNFSPLPAPICPPAPGSASVPHSVPDAFQVPLSVPAPVPHSGLVPVQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 VATSVPAPSPPLAPVPALAPAPPSVPTLISDSNPLSVSASVLVPVPASAPPSGPVPLSAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VATSVPAPSPPLAPVPALAPAPPSVPTLISDSNPLSVSASVLVPVPASAPPSGPVPLSAP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 APAPLSVPVSAPPLALIQAPVPPSAPTLVLAPVPTPVLAPMPASTPPAAPAPPSVPMPTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 APAPLSVPVSAPPLALIQAPVPPSAPTLVLAPVPTPVLAPMPASTPPAAPAPPSVPMPTP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 TPSSGPPSTPTLIPAFAPTPVPAPTPAPIFTPAPTPMPAATPAAIPTSAPIPASFSLSRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TPSSGPPSTPTLIPAFAPTPVPAPTPAPIFTPAPTPMPAATPAAIPTSAPIPASFSLSRV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 CFPAAQAPAMQKVPLSFQPGTVLTPSQPLVYIPPPSCGQPLSVATLPTTLGVSSTLTLPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CFPAAQAPAMQKVPLSFQPGTVLTPSQPLVYIPPPSCGQPLSVATLPTTLGVSSTLTLPV
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 LPSYLQDRCLPGVLASPELRSYPYAFSVARPLTSDSKLVSLEVNRLPCTSPSGSTTTQPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LPSYLQDRCLPGVLASPELRSYPYAFSVARPLTSDSKLVSLEVNRLPCTSPSGSTTTQPA
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 PDGVPGPLADTSLVTASAKVLPTPQPLLPAPSGSSAPPHPAKMPSGTEQQTEGTSVTFSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PDGVPGPLADTSLVTASAKVLPTPQPLLPAPSGSSAPPHPAKMPSGTEQQTEGTSVTFSP
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 LKSPPQLEREMASPPECSEMPLDLSSKSNRQKLPLPNQRKTPPMPVLTPVHTSSKALLST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LKSPPQLEREMASPPECSEMPLDLSSKSNRQKLPLPNQRKTPPMPVLTPVHTSSKALLST
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 VLSRSQRTTQAAGGNVTSCLGSTSSPFVIFPEIVRNGDPSTWVKNSTALISTIPGTYVGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLSRSQRTTQAAGGNVTSCLGSTSSPFVIFPEIVRNGDPSTWVKNSTALISTIPGTYVGV
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 ANPVPASLLLNKDPNLGLNRDPRHLPKQEPISIIDQGEPKGTGATCGKKGSQAGAEGQPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ANPVPASLLLNKDPNLGLNRDPRHLPKQEPISIIDQGEPKGTGATCGKKGSQAGAEGQPS
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE3 TVKRYTPARIAPGLPGCQTKELSLWKPTGPANIYPRCSVNGKPTSTQVLPVGWSPYHQAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TVKRYTPARIAPGLPGCQTKELSLWKPTGPANIYPRCSVNGKPTSTQVLPVGWSPYHQAS
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE3 LLSIGISSAGQLTPSQGAPIRPTSVVSEFSGVPSLSSSEAVHGLPEGQPRPGGSFVPEQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLSIGISSAGQLTPSQGAPIRPTSVVSEFSGVPSLSSSEAVHGLPEGQPRPGGSFVPEQD
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE3 PVTKNKTCRIAAKPYEEQVNPVLLTLSPQTGTLALSVQPSGGDIRMNQGPEESESHLCSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PVTKNKTCRIAAKPYEEQVNPVLLTLSPQTGTLALSVQPSGGDIRMNQGPEESESHLCSD
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE3 STPKMEGPQGACGLKLAGDTKPKNQVLATYMSHELVLATPQNLPKMPELPLLPHDSHPKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 STPKMEGPQGACGLKLAGDTKPKNQVLATYMSHELVLATPQNLPKMPELPLLPHDSHPKE
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE3 LILDVVPSSRRGSSTERPQLGSQVDLGRVKMEKVDGDVVFNLATCFRADGLPVAPQRGQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LILDVVPSSRRGSSTERPQLGSQVDLGRVKMEKVDGDVVFNLATCFRADGLPVAPQRGQA
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE3 EVRAKAGQARVKQESVGVFACKNKWQPDDVTESLPPKKMKCGKEKDSEEQQLQPQAKAVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EVRAKAGQARVKQESVGVFACKNKWQPDDVTESLPPKKMKCGKEKDSEEQQLQPQAKAVV
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE3 RSSHRPKCRKLPSDPQESTKKSPRGASDSGKEHNGVRGKHKHRKPTKPESQSPGKRADSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RSSHRPKCRKLPSDPQESTKKSPRGASDSGKEHNGVRGKHKHRKPTKPESQSPGKRADSH
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE3 EEGSLEKKAKSSFRDFIPVVLSTRTRSQSGSICSSFAGMADSDMGSQEVFPTEEEEEVTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEGSLEKKAKSSFRDFIPVVLSTRTRSQSGSICSSFAGMADSDMGSQEVFPTEEEEEVTP
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE3 TPAKRRKVRKTQRDTQYRSHHAQDKSLLSQGRRHLWRAREMPWRTEAARQMWDTNEEEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TPAKRRKVRKTQRDTQYRSHHAQDKSLLSQGRRHLWRAREMPWRTEAARQMWDTNEEEEE
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE3 EEEEGLLKRKKRRRQKSRKYQTGEYLTEQEDEQRRKGRADLKARKQKTSSSQSLEHRLRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEEEGLLKRKKRRRQKSRKYQTGEYLTEQEDEQRRKGRADLKARKQKTSSSQSLEHRLRN
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430
pF1KE3 RNLLLPNKVQGISDSPNGFLPNNLEEPACLENSEKPSGKRKCKTKHMATVSEEAK-----
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RNLLLPNKVQGISDSPNGFLPNNLEEPACLENSEKPSGKRKCKTKHMATVSEEAKGKGRW
1390 1400 1410 1420 1430 1440
pF1KE3 ------------------------------------------------------------
NP_001 SQQKTRSPKSPTPVKPTEPCTPSKSRSASSEEASESPTARQIPPEARRLIVNKNAGETLL
1450 1460 1470 1480 1490 1500
1440 1450 1460 1470 1480
pF1KE3 ---------DVVLYCLQKDSEDVNHRDNAGYTALHEACSRGWTDILNILLEHGANVNCSA
:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QRAARLGYKDVVLYCLQKDSEDVNHRDNAGYTALHEACSRGWTDILNILLEHGANVNCSA
1510 1520 1530 1540 1550 1560
1490 1500 1510 1520 1530 1540
pF1KE3 QDGTRPVHDAVVNDNLETIWLLLSYGADPTLATYSGQTAMKLASSDTMKRFLSDHLSDLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QDGTRPVHDAVVNDNLETIWLLLSYGADPTLATYSGQTAMKLASSDTMKRFLSDHLSDLQ
1570 1580 1590 1600 1610 1620
1550 1560 1570 1580 1590 1600
pF1KE3 GRAEGDPGVSWDFYSSSVLEEKDGFACDLLHNPPGSSDQEGDDPMEEDDFMFELSDKPLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GRAEGDPGVSWDFYSSSVLEEKDGFACDLLHNPPGSSDQEGDDPMEEDDFMFELSDKPLL
1630 1640 1650 1660 1670 1680
1610 1620 1630 1640 1650 1660
pF1KE3 PCYNLQVSVSRGPCNWFLFSDVLKRLKLSSRIFQARFPHFEITTMPKAEFYRQVASSQLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PCYNLQVSVSRGPCNWFLFSDVLKRLKLSSRIFQARFPHFEITTMPKAEFYRQVASSQLL
1690 1700 1710 1720 1730 1740
1670 1680 1690 1700 1710
pF1KE3 TPAERPGGLDDRSPPGSSETVELVRYEPDLLRLLGSEVEFQSCNS
:::
NP_001 TPAERPGGLDDRSPPGSSETVELVRYEPDLLRLLGSEVEFQSCNS
1750 1760 1770 1780
>>XP_005262512 (OMIM: 300688) PREDICTED: BCL-6 corepress (1785 aa)
initn: 9684 init1: 9684 opt: 9684 Z-score: 3136.2 bits: 593.4 E(85289): 6e-168
Smith-Waterman score: 11129; 95.8% identity (95.8% similar) in 1743 aa overlap (1-1669:1-1743)
10 20 30 40 50 60
pF1KE3 MISTAPLYSGVHNWTSSDRIRMCGINEERRAPLSDEESTTGDCQHFGSQEFCVSSSFSKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MISTAPLYSGVHNWTSSDRIRMCGINEERRAPLSDEESTTGDCQHFGSQEFCVSSSFSKV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 ELTAVGSGSNARGADPDGSATEKLGHKSEDKPDDPQPKMDYAGNVAEAEGLLVPLSSPGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ELTAVGSGSNARGADPDGSATEKLGHKSEDKPDDPQPKMDYAGNVAEAEGLLVPLSSPGD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 GLKLPASDSAEASNSRADCSWTPLNTQMSKQVDCSPAGVKALDSRQGVGEKNTFILATLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GLKLPASDSAEASNSRADCSWTPLNTQMSKQVDCSPAGVKALDSRQGVGEKNTFILATLG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 TGVPVEGTLPLVTTNFSPLPAPICPPAPGSASVPHSVPDAFQVPLSVPAPVPHSGLVPVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TGVPVEGTLPLVTTNFSPLPAPICPPAPGSASVPHSVPDAFQVPLSVPAPVPHSGLVPVQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 VATSVPAPSPPLAPVPALAPAPPSVPTLISDSNPLSVSASVLVPVPASAPPSGPVPLSAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VATSVPAPSPPLAPVPALAPAPPSVPTLISDSNPLSVSASVLVPVPASAPPSGPVPLSAP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 APAPLSVPVSAPPLALIQAPVPPSAPTLVLAPVPTPVLAPMPASTPPAAPAPPSVPMPTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 APAPLSVPVSAPPLALIQAPVPPSAPTLVLAPVPTPVLAPMPASTPPAAPAPPSVPMPTP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 TPSSGPPSTPTLIPAFAPTPVPAPTPAPIFTPAPTPMPAATPAAIPTSAPIPASFSLSRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TPSSGPPSTPTLIPAFAPTPVPAPTPAPIFTPAPTPMPAATPAAIPTSAPIPASFSLSRV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 CFPAAQAPAMQKVPLSFQPGTVLTPSQPLVYIPPPSCGQPLSVATLPTTLGVSSTLTLPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CFPAAQAPAMQKVPLSFQPGTVLTPSQPLVYIPPPSCGQPLSVATLPTTLGVSSTLTLPV
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 LPSYLQDRCLPGVLASPELRSYPYAFSVARPLTSDSKLVSLEVNRLPCTSPSGSTTTQPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LPSYLQDRCLPGVLASPELRSYPYAFSVARPLTSDSKLVSLEVNRLPCTSPSGSTTTQPA
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 PDGVPGPLADTSLVTASAKVLPTPQPLLPAPSGSSAPPHPAKMPSGTEQQTEGTSVTFSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PDGVPGPLADTSLVTASAKVLPTPQPLLPAPSGSSAPPHPAKMPSGTEQQTEGTSVTFSP
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 LKSPPQLEREMASPPECSEMPLDLSSKSNRQKLPLPNQRKTPPMPVLTPVHTSSKALLST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LKSPPQLEREMASPPECSEMPLDLSSKSNRQKLPLPNQRKTPPMPVLTPVHTSSKALLST
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 VLSRSQRTTQAAGGNVTSCLGSTSSPFVIFPEIVRNGDPSTWVKNSTALISTIPGTYVGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VLSRSQRTTQAAGGNVTSCLGSTSSPFVIFPEIVRNGDPSTWVKNSTALISTIPGTYVGV
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 ANPVPASLLLNKDPNLGLNRDPRHLPKQEPISIIDQGEPKGTGATCGKKGSQAGAEGQPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ANPVPASLLLNKDPNLGLNRDPRHLPKQEPISIIDQGEPKGTGATCGKKGSQAGAEGQPS
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE3 TVKRYTPARIAPGLPGCQTKELSLWKPTGPANIYPRCSVNGKPTSTQVLPVGWSPYHQAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TVKRYTPARIAPGLPGCQTKELSLWKPTGPANIYPRCSVNGKPTSTQVLPVGWSPYHQAS
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE3 LLSIGISSAGQLTPSQGAPIRPTSVVSEFSGVPSLSSSEAVHGLPEGQPRPGGSFVPEQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LLSIGISSAGQLTPSQGAPIRPTSVVSEFSGVPSLSSSEAVHGLPEGQPRPGGSFVPEQD
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE3 PVTKNKTCRIAAKPYEEQVNPVLLTLSPQTGTLALSVQPSGGDIRMNQGPEESESHLCSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PVTKNKTCRIAAKPYEEQVNPVLLTLSPQTGTLALSVQPSGGDIRMNQGPEESESHLCSD
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE3 STPKMEGPQGACGLKLAGDTKPKNQVLATYMSHELVLATPQNLPKMPELPLLPHDSHPKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 STPKMEGPQGACGLKLAGDTKPKNQVLATYMSHELVLATPQNLPKMPELPLLPHDSHPKE
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE3 LILDVVPSSRRGSSTERPQLGSQVDLGRVKMEKVDGDVVFNLATCFRADGLPVAPQRGQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LILDVVPSSRRGSSTERPQLGSQVDLGRVKMEKVDGDVVFNLATCFRADGLPVAPQRGQA
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE3 EVRAKAGQARVKQESVGVFACKNKWQPDDVTESLPPKKMKCGKEKDSEEQQLQPQAKAVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EVRAKAGQARVKQESVGVFACKNKWQPDDVTESLPPKKMKCGKEKDSEEQQLQPQAKAVV
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE3 RSSHRPKCRKLPSDPQESTKKSPRGASDSGKEHNGVRGKHKHRKPTKPESQSPGKRADSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RSSHRPKCRKLPSDPQESTKKSPRGASDSGKEHNGVRGKHKHRKPTKPESQSPGKRADSH
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE3 EEGSLEKKAKSSFRDFIPVVLSTRTRSQSGSICSSFAGMADSDMGSQEVFPTEEEEEVTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EEGSLEKKAKSSFRDFIPVVLSTRTRSQSGSICSSFAGMADSDMGSQEVFPTEEEEEVTP
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE3 TPAKRRKVRKTQRDTQYRSHHAQDKSLLSQGRRHLWRAREMPWRTEAARQMWDTNEEEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TPAKRRKVRKTQRDTQYRSHHAQDKSLLSQGRRHLWRAREMPWRTEAARQMWDTNEEEEE
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE3 EEEEGLLKRKKRRRQKSRKYQTGEYLTEQEDEQRRKGRADLKARKQKTSSSQSLEHRLRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EEEEGLLKRKKRRRQKSRKYQTGEYLTEQEDEQRRKGRADLKARKQKTSSSQSLEHRLRN
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430
pF1KE3 RNLLLPNKVQGISDSPNGFLPNNLEEPACLENSEKPSGKRKCKTKHMATVSEEAK-----
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RNLLLPNKVQGISDSPNGFLPNNLEEPACLENSEKPSGKRKCKTKHMATVSEEAKGKGRW
1390 1400 1410 1420 1430 1440
pF1KE3 ------------------------------------------------------------
XP_005 SQQKTRSPKSPTPVKPTEPCTPSKSRSASSEEASESPTARQIPPEARRLIVNKNAGETLL
1450 1460 1470 1480 1490 1500
1440 1450 1460 1470 1480
pF1KE3 ---------DVVLYCLQKDSEDVNHRDNAGYTALHEACSRGWTDILNILLEHGANVNCSA
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QRAARLGYKDVVLYCLQKDSEDVNHRDNAGYTALHEACSRGWTDILNILLEHGANVNCSA
1510 1520 1530 1540 1550 1560
1490 1500 1510 1520 1530 1540
pF1KE3 QDGTRPVHDAVVNDNLETIWLLLSYGADPTLATYSGQTAMKLASSDTMKRFLSDHLSDLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QDGTRPVHDAVVNDNLETIWLLLSYGADPTLATYSGQTAMKLASSDTMKRFLSDHLSDLQ
1570 1580 1590 1600 1610 1620
1550 1560 1570 1580 1590 1600
pF1KE3 GRAEGDPGVSWDFYSSSVLEEKDGFACDLLHNPPGSSDQEGDDPMEEDDFMFELSDKPLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GRAEGDPGVSWDFYSSSVLEEKDGFACDLLHNPPGSSDQEGDDPMEEDDFMFELSDKPLL
1630 1640 1650 1660 1670 1680
1610 1620 1630 1640 1650 1660
pF1KE3 PCYNLQVSVSRGPCNWFLFSDVLKRLKLSSRIFQARFPHFEITTMPKAEFYRQVASSQLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PCYNLQVSVSRGPCNWFLFSDVLKRLKLSSRIFQARFPHFEITTMPKAEFYRQVASSQLL
1690 1700 1710 1720 1730 1740
1670 1680 1690 1700 1710
pF1KE3 TPAERPGGLDDRSPPGSSETVELVRYEPDLLRLLGSEVEFQSCNS
:::
XP_005 TPAERPGGLDDRSPPGSSETVELVRYEPDLLRLLGSEVEFQSCNS
1750 1760 1770 1780
1711 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 08:38:39 2016 done: Sun Nov 6 08:38:42 2016
Total Scan time: 25.770 Total Display time: 1.120
Function used was FASTA [36.3.4 Apr, 2011]