Result of FASTA (omim) for
pFN21AE3941
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3941, 587 aa
1>>>pF1KE3941 587 - 587 aa - 587 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.3911+/-0.000338; mu= 11.8220+/- 0.021
mean_var=186.7550+/-39.661, 0's: 0 Z-trim(120.7): 283 B-trim: 35 in 1/52
Lambda= 0.093851
statistics sampled from 36078 (36403) to 36078 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.738), E-opt: 0.2 (0.427), width: 16
Scan time: 12.670
The best scores are: opt bits E(85289)
NP_653254 (OMIM: 615786) nucleus accumbens-associa ( 587) 3912 542.2 1.8e-153
XP_011516523 (OMIM: 615786) PREDICTED: nucleus acc ( 587) 3912 542.2 1.8e-153
NP_443108 (OMIM: 610672) nucleus accumbens-associa ( 527) 1020 150.5 1.3e-35
XP_005259778 (OMIM: 610672) PREDICTED: nucleus acc ( 527) 1020 150.5 1.3e-35
NP_001092740 (OMIM: 611692) zinc finger and BTB do ( 500) 354 60.3 1.7e-08
XP_011517001 (OMIM: 611692) PREDICTED: zinc finger ( 504) 354 60.3 1.7e-08
XP_005252046 (OMIM: 611692) PREDICTED: zinc finger ( 514) 354 60.3 1.8e-08
NP_005444 (OMIM: 611439) zinc finger and BTB domai ( 634) 325 56.5 3.1e-07
NP_001138810 (OMIM: 611439) zinc finger and BTB do ( 634) 325 56.5 3.1e-07
NP_001157818 (OMIM: 259050,606025) zinc finger and ( 668) 283 50.8 1.6e-05
NP_056457 (OMIM: 259050,606025) zinc finger and BT ( 668) 283 50.8 1.6e-05
NP_001157816 (OMIM: 259050,606025) zinc finger and ( 668) 283 50.8 1.6e-05
NP_001157815 (OMIM: 259050,606025) zinc finger and ( 668) 283 50.8 1.6e-05
NP_001157817 (OMIM: 259050,606025) zinc finger and ( 668) 283 50.8 1.6e-05
NP_001157819 (OMIM: 259050,606025) zinc finger and ( 668) 283 50.8 1.6e-05
NP_001157814 (OMIM: 259050,606025) zinc finger and ( 741) 283 50.9 1.8e-05
XP_011524172 (OMIM: 616591) PREDICTED: zinc finger ( 619) 256 47.2 0.0002
XP_016881098 (OMIM: 616591) PREDICTED: zinc finger ( 619) 256 47.2 0.0002
NP_001034449 (OMIM: 616591) zinc finger and BTB do ( 619) 256 47.2 0.0002
XP_005258286 (OMIM: 616591) PREDICTED: zinc finger ( 619) 256 47.2 0.0002
NP_001305770 (OMIM: 616591) zinc finger and BTB do ( 619) 256 47.2 0.0002
XP_011524173 (OMIM: 616591) PREDICTED: zinc finger ( 619) 256 47.2 0.0002
XP_016881097 (OMIM: 616591) PREDICTED: zinc finger ( 627) 256 47.2 0.0002
XP_011524171 (OMIM: 616591) PREDICTED: zinc finger ( 627) 256 47.2 0.0002
XP_016881096 (OMIM: 616591) PREDICTED: zinc finger ( 628) 256 47.2 0.0002
XP_011524165 (OMIM: 616591) PREDICTED: zinc finger ( 628) 256 47.2 0.0002
XP_011524167 (OMIM: 616591) PREDICTED: zinc finger ( 628) 256 47.2 0.0002
XP_011524169 (OMIM: 616591) PREDICTED: zinc finger ( 628) 256 47.2 0.0002
XP_011524166 (OMIM: 616591) PREDICTED: zinc finger ( 628) 256 47.2 0.0002
XP_016881095 (OMIM: 616591) PREDICTED: zinc finger ( 628) 256 47.2 0.0002
XP_011524168 (OMIM: 616591) PREDICTED: zinc finger ( 628) 256 47.2 0.0002
XP_011524163 (OMIM: 616591) PREDICTED: zinc finger ( 668) 256 47.2 0.00021
XP_016881094 (OMIM: 616591) PREDICTED: zinc finger ( 668) 256 47.2 0.00021
NP_001131073 (OMIM: 613915,616248) zinc finger and ( 422) 252 46.4 0.00022
XP_016876400 (OMIM: 613915,616248) PREDICTED: zinc ( 422) 252 46.4 0.00022
XP_005271715 (OMIM: 176797,612447) PREDICTED: zinc ( 485) 248 46.0 0.00035
NP_005997 (OMIM: 176797,612447) zinc finger and BT ( 673) 248 46.1 0.00044
NP_001018011 (OMIM: 176797,612447) zinc finger and ( 673) 248 46.1 0.00044
XP_016873746 (OMIM: 176797,612447) PREDICTED: zinc ( 673) 248 46.1 0.00044
XP_016873747 (OMIM: 176797,612447) PREDICTED: zinc ( 673) 248 46.1 0.00044
XP_016873748 (OMIM: 176797,612447) PREDICTED: zinc ( 673) 248 46.1 0.00044
NP_003434 (OMIM: 604084) zinc finger and BTB domai ( 803) 249 46.3 0.00046
NP_001274532 (OMIM: 604084) zinc finger and BTB do ( 810) 249 46.3 0.00046
NP_862827 (OMIM: 608992) B-cell CLL/lymphoma 6 mem ( 480) 244 45.4 0.00051
XP_005248008 (OMIM: 616238) PREDICTED: zinc finger ( 466) 240 44.9 0.00073
XP_011526851 (OMIM: 614639) PREDICTED: zinc finger ( 415) 239 44.7 0.00074
XP_016883156 (OMIM: 614639) PREDICTED: zinc finger ( 432) 239 44.7 0.00076
XP_011507901 (OMIM: 607646) PREDICTED: zinc finger ( 539) 240 44.9 0.0008
NP_001243384 (OMIM: 607646) zinc finger and BTB do ( 539) 240 44.9 0.0008
XP_006711422 (OMIM: 607646) PREDICTED: zinc finger ( 539) 240 44.9 0.0008
>>NP_653254 (OMIM: 615786) nucleus accumbens-associated (587 aa)
initn: 3912 init1: 3912 opt: 3912 Z-score: 2876.1 bits: 542.2 E(85289): 1.8e-153
Smith-Waterman score: 3912; 100.0% identity (100.0% similar) in 587 aa overlap (1-587:1-587)
10 20 30 40 50 60
pF1KE3 MSQMLHIEIPNFGNTVLGCLNEQRLLGLYCDVSIVVKGQAFKAHRAVLAASSLYFRDLFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_653 MSQMLHIEIPNFGNTVLGCLNEQRLLGLYCDVSIVVKGQAFKAHRAVLAASSLYFRDLFS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 GNSKSAFELPGSVPPACFQQILSFCYTGRLTMTASEQLVVMYTAGFLQIQHIVERGTDLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_653 GNSKSAFELPGSVPPACFQQILSFCYTGRLTMTASEQLVVMYTAGFLQIQHIVERGTDLM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 FKVSSPHCDSQTAVIEDAGSEPQSPCNQLQPAAAAAAPYVVSPSVPIPLLTRVKHEAMEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_653 FKVSSPHCDSQTAVIEDAGSEPQSPCNQLQPAAAAAAPYVVSPSVPIPLLTRVKHEAMEL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 PPAGPGLAPKRPLETGPRDGVAVAAGAAVAAGTAPLKLPRVSYYGVPSLATLIPGIQQMP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_653 PPAGPGLAPKRPLETGPRDGVAVAAGAAVAAGTAPLKLPRVSYYGVPSLATLIPGIQQMP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 YPQGERTSPGASSLPTTDSPTSYHNEEDEEDDEAYDTMVEEQYGQMYIKASGSYAVQEKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_653 YPQGERTSPGASSLPTTDSPTSYHNEEDEEDDEAYDTMVEEQYGQMYIKASGSYAVQEKP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 EPVPLESRSCVLIRRDLVALPASLISQIGYRCHPKLYSEGDPGEKLELVAGSGVYITRGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_653 EPVPLESRSCVLIRRDLVALPASLISQIGYRCHPKLYSEGDPGEKLELVAGSGVYITRGQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 LMNCHLCAGVKHKVLLRRLLATFFDRNTLANSCGTGIRSSTSDPSRKPLDSRVLNAVKLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_653 LMNCHLCAGVKHKVLLRRLLATFFDRNTLANSCGTGIRSSTSDPSRKPLDSRVLNAVKLY
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 CQNFAPSFKESEMNVIAADMCTNARRVRKRWLPKIKSMLPEGVEMYRTVMGSAAASVPLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_653 CQNFAPSFKESEMNVIAADMCTNARRVRKRWLPKIKSMLPEGVEMYRTVMGSAAASVPLD
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 PEFPPAAAQVFEQRIYAERRGDAATIVALRTDAVNVDLSAAANPAFDAGEEVDGAGSVIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_653 PEFPPAAAQVFEQRIYAERRGDAATIVALRTDAVNVDLSAAANPAFDAGEEVDGAGSVIQ
490 500 510 520 530 540
550 560 570 580
pF1KE3 EVAAPEPLPADGQSPPQPFEQGGGGPSRPQTPAAAARRPEGTYAGTL
:::::::::::::::::::::::::::::::::::::::::::::::
NP_653 EVAAPEPLPADGQSPPQPFEQGGGGPSRPQTPAAAARRPEGTYAGTL
550 560 570 580
>>XP_011516523 (OMIM: 615786) PREDICTED: nucleus accumbe (587 aa)
initn: 3912 init1: 3912 opt: 3912 Z-score: 2876.1 bits: 542.2 E(85289): 1.8e-153
Smith-Waterman score: 3912; 100.0% identity (100.0% similar) in 587 aa overlap (1-587:1-587)
10 20 30 40 50 60
pF1KE3 MSQMLHIEIPNFGNTVLGCLNEQRLLGLYCDVSIVVKGQAFKAHRAVLAASSLYFRDLFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSQMLHIEIPNFGNTVLGCLNEQRLLGLYCDVSIVVKGQAFKAHRAVLAASSLYFRDLFS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 GNSKSAFELPGSVPPACFQQILSFCYTGRLTMTASEQLVVMYTAGFLQIQHIVERGTDLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GNSKSAFELPGSVPPACFQQILSFCYTGRLTMTASEQLVVMYTAGFLQIQHIVERGTDLM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 FKVSSPHCDSQTAVIEDAGSEPQSPCNQLQPAAAAAAPYVVSPSVPIPLLTRVKHEAMEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FKVSSPHCDSQTAVIEDAGSEPQSPCNQLQPAAAAAAPYVVSPSVPIPLLTRVKHEAMEL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 PPAGPGLAPKRPLETGPRDGVAVAAGAAVAAGTAPLKLPRVSYYGVPSLATLIPGIQQMP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPAGPGLAPKRPLETGPRDGVAVAAGAAVAAGTAPLKLPRVSYYGVPSLATLIPGIQQMP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 YPQGERTSPGASSLPTTDSPTSYHNEEDEEDDEAYDTMVEEQYGQMYIKASGSYAVQEKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YPQGERTSPGASSLPTTDSPTSYHNEEDEEDDEAYDTMVEEQYGQMYIKASGSYAVQEKP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 EPVPLESRSCVLIRRDLVALPASLISQIGYRCHPKLYSEGDPGEKLELVAGSGVYITRGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EPVPLESRSCVLIRRDLVALPASLISQIGYRCHPKLYSEGDPGEKLELVAGSGVYITRGQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 LMNCHLCAGVKHKVLLRRLLATFFDRNTLANSCGTGIRSSTSDPSRKPLDSRVLNAVKLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LMNCHLCAGVKHKVLLRRLLATFFDRNTLANSCGTGIRSSTSDPSRKPLDSRVLNAVKLY
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 CQNFAPSFKESEMNVIAADMCTNARRVRKRWLPKIKSMLPEGVEMYRTVMGSAAASVPLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CQNFAPSFKESEMNVIAADMCTNARRVRKRWLPKIKSMLPEGVEMYRTVMGSAAASVPLD
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 PEFPPAAAQVFEQRIYAERRGDAATIVALRTDAVNVDLSAAANPAFDAGEEVDGAGSVIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PEFPPAAAQVFEQRIYAERRGDAATIVALRTDAVNVDLSAAANPAFDAGEEVDGAGSVIQ
490 500 510 520 530 540
550 560 570 580
pF1KE3 EVAAPEPLPADGQSPPQPFEQGGGGPSRPQTPAAAARRPEGTYAGTL
:::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EVAAPEPLPADGQSPPQPFEQGGGGPSRPQTPAAAARRPEGTYAGTL
550 560 570 580
>>NP_443108 (OMIM: 610672) nucleus accumbens-associated (527 aa)
initn: 1662 init1: 800 opt: 1020 Z-score: 760.5 bits: 150.5 E(85289): 1.3e-35
Smith-Waterman score: 1666; 56.6% identity (72.8% similar) in 523 aa overlap (1-478:1-501)
10 20 30 40 50 60
pF1KE3 MSQMLHIEIPNFGNTVLGCLNEQRLLGLYCDVSIVVKGQAFKAHRAVLAASSLYFRDLFS
:.: :..:::::::..: ::::::: :::::::.::::.::::::::::::: ::::::.
NP_443 MAQTLQMEIPNFGNSILECLNEQRLQGLYCDVSVVVKGHAFKAHRAVLAASSSYFRDLFN
10 20 30 40 50 60
70 80 90 100 110
pF1KE3 GNSKSAF-ELPGSVPPACFQQILSFCYTGRLTMTASEQLVVMYTAGFLQIQHIVERGTDL
::.:: :::..: : :::::::::::::.:....:...::::::::::.:.:.::..
NP_443 -NSRSAVVELPAAVQPQSFQQILSFCYTGRLSMNVGDQFLLMYTAGFLQIQEIMEKGTEF
70 80 90 100 110
120 130 140 150 160 170
pF1KE3 MFKVSSPHCDSQTAVIEDA-GSEPQSPCNQLQPAAAAAAPYVVSPSVPIPLLTRVKHEAM
..::::: :::: :.: .:::::: : . : :.:.::..::: : .
NP_443 FLKVSSPSCDSQGLHAEEAPSSEPQSPVAQTSGWPAC--------STPLPLVSRVKTEQQ
120 130 140 150 160 170
180 190 200
pF1KE3 E------LP-----------PAG--------------PGLAPKRPLETGPRDGVAVAAGA
: .: :: : :: .:: . : . . :.:.:
NP_443 ESDSVQCMPVAKRLWDSGQKEAGGGGNGSRKMAKFSTPDLAANRPHQPPPPQQAPVVAAA
180 190 200 210 220 230
210 220 230 240 250 260
pF1KE3 --AVAAGTAPLKLPRVSYYGVPSLATLIPGIQQMPYPQGERTSPGASSLPTTDSPTSYHN
:::::.. : :: . . .. : : .::::::.:: :.::: ::::
NP_443 QPAVAAGAGQ---PA---GGVAAAGGVVSG----P-STSERTSPGTSSAYTSDSPGSYHN
240 250 260 270 280
270 280 290 300 310
pF1KE3 EEDEEDDEAYDTMVEEQYGQ---MYIKAS----GSYA--VQEKPEPVPLESRSCVLIRRD
:::::.: . . : .::: : :: : :. : :. :: : :::. . .:.:
NP_443 EEDEEEDGGEEGM-DEQYRQICNMYTMYSMMNVGQTAEKVEALPEQVAPESRNRIRVRQD
290 300 310 320 330
320 330 340 350 360 370
pF1KE3 LVALPASLISQIGYRCHPKLYSEGDPGEKLELVAGSGVYITRGQLMNCHLCAGVKHKVLL
:..::: ::.::: :::::::.::::.::::::.:..:::::.::::::. ::..:::::
NP_443 LASLPAELINQIGNRCHPKLYDEGDPSEKLELVTGTNVYITRAQLMNCHVSAGTRHKVLL
340 350 360 370 380 390
380 390 400 410 420 430
pF1KE3 RRLLATFFDRNTLANSCGTGIRSSTSDPSRKPLDSRVLNAVKLYCQNFAPSFKESEMNVI
:::::.:::::::::::::::::::.:: :::::::::.::: :::::::.:::::::.:
NP_443 RRLLASFFDRNTLANSCGTGIRSSTNDPRRKPLDSRVLHAVKYYCQNFAPNFKESEMNAI
400 410 420 430 440 450
440 450 460 470 480 490
pF1KE3 AADMCTNARRV-RKRWLPKIKSMLPEGVEMYRTVMGSAAASVPLDPEFPPAAAQVFEQRI
::::::::::: :: :.::.: . : . : : .. .. :
NP_443 AADMCTNARRVVRKSWMPKVKVLKAED-DAYTTFISETGKIEPDMMGVEHGFETASHEGE
460 470 480 490 500 510
500 510 520 530 540 550
pF1KE3 YAERRGDAATIVALRTDAVNVDLSAAANPAFDAGEEVDGAGSVIQEVAAPEPLPADGQSP
NP_443 AGPSAEALQ
520
>>XP_005259778 (OMIM: 610672) PREDICTED: nucleus accumbe (527 aa)
initn: 1662 init1: 800 opt: 1020 Z-score: 760.5 bits: 150.5 E(85289): 1.3e-35
Smith-Waterman score: 1666; 56.6% identity (72.8% similar) in 523 aa overlap (1-478:1-501)
10 20 30 40 50 60
pF1KE3 MSQMLHIEIPNFGNTVLGCLNEQRLLGLYCDVSIVVKGQAFKAHRAVLAASSLYFRDLFS
:.: :..:::::::..: ::::::: :::::::.::::.::::::::::::: ::::::.
XP_005 MAQTLQMEIPNFGNSILECLNEQRLQGLYCDVSVVVKGHAFKAHRAVLAASSSYFRDLFN
10 20 30 40 50 60
70 80 90 100 110
pF1KE3 GNSKSAF-ELPGSVPPACFQQILSFCYTGRLTMTASEQLVVMYTAGFLQIQHIVERGTDL
::.:: :::..: : :::::::::::::.:....:...::::::::::.:.:.::..
XP_005 -NSRSAVVELPAAVQPQSFQQILSFCYTGRLSMNVGDQFLLMYTAGFLQIQEIMEKGTEF
70 80 90 100 110
120 130 140 150 160 170
pF1KE3 MFKVSSPHCDSQTAVIEDA-GSEPQSPCNQLQPAAAAAAPYVVSPSVPIPLLTRVKHEAM
..::::: :::: :.: .:::::: : . : :.:.::..::: : .
XP_005 FLKVSSPSCDSQGLHAEEAPSSEPQSPVAQTSGWPAC--------STPLPLVSRVKTEQQ
120 130 140 150 160 170
180 190 200
pF1KE3 E------LP-----------PAG--------------PGLAPKRPLETGPRDGVAVAAGA
: .: :: : :: .:: . : . . :.:.:
XP_005 ESDSVQCMPVAKRLWDSGQKEAGGGGNGSRKMAKFSTPDLAANRPHQPPPPQQAPVVAAA
180 190 200 210 220 230
210 220 230 240 250 260
pF1KE3 --AVAAGTAPLKLPRVSYYGVPSLATLIPGIQQMPYPQGERTSPGASSLPTTDSPTSYHN
:::::.. : :: . . .. : : .::::::.:: :.::: ::::
XP_005 QPAVAAGAGQ---PA---GGVAAAGGVVSG----P-STSERTSPGTSSAYTSDSPGSYHN
240 250 260 270 280
270 280 290 300 310
pF1KE3 EEDEEDDEAYDTMVEEQYGQ---MYIKAS----GSYA--VQEKPEPVPLESRSCVLIRRD
:::::.: . . : .::: : :: : :. : :. :: : :::. . .:.:
XP_005 EEDEEEDGGEEGM-DEQYRQICNMYTMYSMMNVGQTAEKVEALPEQVAPESRNRIRVRQD
290 300 310 320 330
320 330 340 350 360 370
pF1KE3 LVALPASLISQIGYRCHPKLYSEGDPGEKLELVAGSGVYITRGQLMNCHLCAGVKHKVLL
:..::: ::.::: :::::::.::::.::::::.:..:::::.::::::. ::..:::::
XP_005 LASLPAELINQIGNRCHPKLYDEGDPSEKLELVTGTNVYITRAQLMNCHVSAGTRHKVLL
340 350 360 370 380 390
380 390 400 410 420 430
pF1KE3 RRLLATFFDRNTLANSCGTGIRSSTSDPSRKPLDSRVLNAVKLYCQNFAPSFKESEMNVI
:::::.:::::::::::::::::::.:: :::::::::.::: :::::::.:::::::.:
XP_005 RRLLASFFDRNTLANSCGTGIRSSTNDPRRKPLDSRVLHAVKYYCQNFAPNFKESEMNAI
400 410 420 430 440 450
440 450 460 470 480 490
pF1KE3 AADMCTNARRV-RKRWLPKIKSMLPEGVEMYRTVMGSAAASVPLDPEFPPAAAQVFEQRI
::::::::::: :: :.::.: . : . : : .. .. :
XP_005 AADMCTNARRVVRKSWMPKVKVLKAED-DAYTTFISETGKIEPDMMGVEHGFETASHEGE
460 470 480 490 500 510
500 510 520 530 540 550
pF1KE3 YAERRGDAATIVALRTDAVNVDLSAAANPAFDAGEEVDGAGSVIQEVAAPEPLPADGQSP
XP_005 AGPSAEALQ
520
>>NP_001092740 (OMIM: 611692) zinc finger and BTB domain (500 aa)
initn: 348 init1: 348 opt: 354 Z-score: 273.4 bits: 60.3 E(85289): 1.7e-08
Smith-Waterman score: 354; 36.1% identity (68.1% similar) in 166 aa overlap (2-163:4-165)
10 20 30 40 50
pF1KE3 MSQMLHIEIPNFGNTVLGCLNEQRLLGLYCDVSIVVKGQAFKAHRAVLAASSLYFRDL
:.......:....:::. ::: :: : ::. . ..:: :.::.::::::: ::::
NP_001 MDSSSFIQFDVPEYSSTVLSQLNELRLQGKLCDIIVHIQGQPFRAHKAVLAASSPYFRDH
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE3 FSGNSKSAFELPGSVPPACFQQILSFCYTGRLTMTASEQLVVMYTAGFLQIQHIVERGTD
. .. :.. . : :.:.::::::::... .. . . .:.:::.: .... :.
NP_001 SALSTMSGLSISVIKNPNVFEQLLSFCYTGRMSLQLKDVVSFLTAASFLQMQCVIDKCTQ
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE3 LMF----KVSSPHCDSQTAVIEDAGSEPQSPCNQLQPAAAAAAPYVVSPSVPIPLLTRVK
.. :.: :: :. :. .:.: : .. .. : : .::
NP_001 ILESIHSKISVGDVDSVTVGAEE---NPESR-NGVKDSSFFANPVEISPPYCSQGRQPTA
130 140 150 160 170
180 190 200 210 220 230
pF1KE3 HEAMELPPAGPGLAPKRPLETGPRDGVAVAAGAAVAAGTAPLKLPRVSYYGVPSLATLIP
NP_001 SSDLRMETTPSKALRSRLQEEGHSDRGSSGSVSEYEIQIEGDHEQGDLLVRESQITEVKV
180 190 200 210 220 230
>>XP_011517001 (OMIM: 611692) PREDICTED: zinc finger and (504 aa)
initn: 348 init1: 348 opt: 354 Z-score: 273.4 bits: 60.3 E(85289): 1.7e-08
Smith-Waterman score: 354; 36.1% identity (68.1% similar) in 166 aa overlap (2-163:8-169)
10 20 30 40 50
pF1KE3 MSQMLHIEIPNFGNTVLGCLNEQRLLGLYCDVSIVVKGQAFKAHRAVLAASSLY
:.......:....:::. ::: :: : ::. . ..:: :.::.::::::: :
XP_011 MSVEMDSSSFIQFDVPEYSSTVLSQLNELRLQGKLCDIIVHIQGQPFRAHKAVLAASSPY
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE3 FRDLFSGNSKSAFELPGSVPPACFQQILSFCYTGRLTMTASEQLVVMYTAGFLQIQHIVE
::: . .. :.. . : :.:.::::::::... .. . . .:.:::.: ...
XP_011 FRDHSALSTMSGLSISVIKNPNVFEQLLSFCYTGRMSLQLKDVVSFLTAASFLQMQCVID
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE3 RGTDLMF----KVSSPHCDSQTAVIEDAGSEPQSPCNQLQPAAAAAAPYVVSPSVPIPLL
. :... :.: :: :. :. .:.: : .. .. : : .::
XP_011 KCTQILESIHSKISVGDVDSVTVGAEE---NPESR-NGVKDSSFFANPVEISPPYCSQGR
130 140 150 160 170
180 190 200 210 220 230
pF1KE3 TRVKHEAMELPPAGPGLAPKRPLETGPRDGVAVAAGAAVAAGTAPLKLPRVSYYGVPSLA
XP_011 QPTASSDLRMETTPSKALRSRLQEEGHSDRGSSGSVSEYEIQIEGDHEQGDLLVRESQIT
180 190 200 210 220 230
>>XP_005252046 (OMIM: 611692) PREDICTED: zinc finger and (514 aa)
initn: 348 init1: 348 opt: 354 Z-score: 273.3 bits: 60.3 E(85289): 1.8e-08
Smith-Waterman score: 354; 36.1% identity (68.1% similar) in 166 aa overlap (2-163:18-179)
10 20 30 40
pF1KE3 MSQMLHIEIPNFGNTVLGCLNEQRLLGLYCDVSIVVKGQAFKAH
:.......:....:::. ::: :: : ::. . ..:: :.::
XP_005 MEECKSRVRFMSVEMDSSSFIQFDVPEYSSTVLSQLNELRLQGKLCDIIVHIQGQPFRAH
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE3 RAVLAASSLYFRDLFSGNSKSAFELPGSVPPACFQQILSFCYTGRLTMTASEQLVVMYTA
.::::::: :::: . .. :.. . : :.:.::::::::... .. . . .:
XP_005 KAVLAASSPYFRDHSALSTMSGLSISVIKNPNVFEQLLSFCYTGRMSLQLKDVVSFLTAA
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE3 GFLQIQHIVERGTDLMF----KVSSPHCDSQTAVIEDAGSEPQSPCNQLQPAAAAAAPYV
.:::.: .... :... :.: :: :. :. .:.: : .. .. : :
XP_005 SFLQMQCVIDKCTQILESIHSKISVGDVDSVTVGAEE---NPESR-NGVKDSSFFANPVE
130 140 150 160 170
170 180 190 200 210 220
pF1KE3 VSPSVPIPLLTRVKHEAMELPPAGPGLAPKRPLETGPRDGVAVAAGAAVAAGTAPLKLPR
.::
XP_005 ISPPYCSQGRQPTASSDLRMETTPSKALRSRLQEEGHSDRGSSGSVSEYEIQIEGDHEQG
180 190 200 210 220 230
>>NP_005444 (OMIM: 611439) zinc finger and BTB domain-co (634 aa)
initn: 348 init1: 318 opt: 325 Z-score: 250.9 bits: 56.5 E(85289): 3.1e-07
Smith-Waterman score: 325; 28.8% identity (59.9% similar) in 267 aa overlap (4-262:31-290)
10 20 30
pF1KE3 MSQMLHIEIPNFGNTVLGCLNEQRLLGLYCDVS
..:. .:. ...: ::.::: : ::::
NP_005 MEPSPLSPSGAALPLPLSLAPPPLPLPAAAVVHVSFPEVTSALLESLNQQRLQGQLCDVS
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE3 IVVKGQAFKAHRAVLAASSLYFRDLFSGNSKSAFELPGSVPPACFQQILSFCYTGRLTMT
: :.:. :.:::::::::: ::.: .. ... ::. . :. :. .:. :::::.:.
NP_005 IRVQGREFRAHRAVLAASSPYFHDQVLLKGMTSISLPSVMDPGAFETVLASAYTGRLSMA
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE3 ASEQLVVMYTAGFLQIQHIVERGTDLMFKVSSPHCDSQTAVIEDAGSEPQSPCNQLQPAA
:.. . . ... ::. :::.. :.:. . .. :.. :.. : . :..
NP_005 AADIVNFLTVGSVLQMWHIVDKCTELL---REGRASATTTITTAAATSVTVPGAGV-PSG
130 140 150 160 170
160 170 180 190 200 210
pF1KE3 AAAAPYVVSPSVPIPLLTRVKHEAME--LPPAGPGLAPKRPLETGPRDGVAVAAGAAVAA
.... :.:.. .... .: : : .. ..:.. . . . : ::.:. ..
NP_005 SGGT---VAPATMGSARSHASSRASENQSPSSSNYFSPRESTDFSSSSQEAFAASAVGSG
180 190 200 210 220 230
220 230 240 250 260
pF1KE3 ---GTAPL-KLPRVSYYGVPSLATLIPGIQQMPYPQGERTS--PGASSLPTTDSPTSYHN
: .:. : :. :. : :. . . : . :::. : .: :
NP_005 ERRGGGPVFPAPVVGSGGATSGKLLLEADELCDDGGDGRGAVVPGAGLRRPTYTPPSIMP
240 250 260 270 280 290
270 280 290 300 310 320
pF1KE3 EEDEEDDEAYDTMVEEQYGQMYIKASGSYAVQEKPEPVPLESRSCVLIRRDLVALPASLI
NP_005 QKHWVYVKRGGNCPAPTPLVPQDPDLEEEEEEEDLVLTCEDDEDEELGGSSRVPVGGGPE
300 310 320 330 340 350
>>NP_001138810 (OMIM: 611439) zinc finger and BTB domain (634 aa)
initn: 348 init1: 318 opt: 325 Z-score: 250.9 bits: 56.5 E(85289): 3.1e-07
Smith-Waterman score: 325; 28.8% identity (59.9% similar) in 267 aa overlap (4-262:31-290)
10 20 30
pF1KE3 MSQMLHIEIPNFGNTVLGCLNEQRLLGLYCDVS
..:. .:. ...: ::.::: : ::::
NP_001 MEPSPLSPSGAALPLPLSLAPPPLPLPAAAVVHVSFPEVTSALLESLNQQRLQGQLCDVS
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE3 IVVKGQAFKAHRAVLAASSLYFRDLFSGNSKSAFELPGSVPPACFQQILSFCYTGRLTMT
: :.:. :.:::::::::: ::.: .. ... ::. . :. :. .:. :::::.:.
NP_001 IRVQGREFRAHRAVLAASSPYFHDQVLLKGMTSISLPSVMDPGAFETVLASAYTGRLSMA
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE3 ASEQLVVMYTAGFLQIQHIVERGTDLMFKVSSPHCDSQTAVIEDAGSEPQSPCNQLQPAA
:.. . . ... ::. :::.. :.:. . .. :.. :.. : . :..
NP_001 AADIVNFLTVGSVLQMWHIVDKCTELL---REGRASATTTITTAAATSVTVPGAGV-PSG
130 140 150 160 170
160 170 180 190 200 210
pF1KE3 AAAAPYVVSPSVPIPLLTRVKHEAME--LPPAGPGLAPKRPLETGPRDGVAVAAGAAVAA
.... :.:.. .... .: : : .. ..:.. . . . : ::.:. ..
NP_001 SGGT---VAPATMGSARSHASSRASENQSPSSSNYFSPRESTDFSSSSQEAFAASAVGSG
180 190 200 210 220 230
220 230 240 250 260
pF1KE3 ---GTAPL-KLPRVSYYGVPSLATLIPGIQQMPYPQGERTS--PGASSLPTTDSPTSYHN
: .:. : :. :. : :. . . : . :::. : .: :
NP_001 ERRGGGPVFPAPVVGSGGATSGKLLLEADELCDDGGDGRGAVVPGAGLRRPTYTPPSIMP
240 250 260 270 280 290
270 280 290 300 310 320
pF1KE3 EEDEEDDEAYDTMVEEQYGQMYIKASGSYAVQEKPEPVPLESRSCVLIRRDLVALPASLI
NP_001 QKHWVYVKRGGNCPAPTPLVPQDPDLEEEEEEEDLVLTCEDDEDEELGGSSRVPVGGGPE
300 310 320 330 340 350
>>NP_001157818 (OMIM: 259050,606025) zinc finger and BTB (668 aa)
initn: 257 init1: 171 opt: 283 Z-score: 219.9 bits: 50.8 E(85289): 1.6e-05
Smith-Waterman score: 300; 28.8% identity (56.2% similar) in 299 aa overlap (1-289:1-273)
10 20 30 40 50
pF1KE3 MSQMLH-IEIPNFGNTVLGCLNEQRLLGLYCDVSIVVKGQAFKAHRAVLAASSLYFRD-L
:.. .: :.. ::.:.:: ::::: : .:::.. ..:. ..::: ::::.: .:.: :
NP_001 MTERIHSINLHNFSNSVLETLNEQRNRGHFCDVTVRIHGSMLRAHRCVLAAGSPFFQDKL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE3 FSGNSKSAFELPGSVPPACFQQILSFCYTGRLTMTASEQLVVMYTAGFLQIQHIVERGTD
. : : .:.:. : :....: :.: : .. :: : .. .:..:::. .... :
NP_001 LLGYSD--IEIPSVVSVQSVQKLIDFMYSGVLRVSQSEALQILTAASILQIKTVIDECT-
70 80 90 100 110
120 130 140 150 160 170
pF1KE3 LMFKVSSPHCDSQTAVIEDAGSEPQSPCNQLQPAAAAAAPYVVSPSVPIPLLTRVKHEAM
.. : . . :.:.:.. .: . : ..... : . : .. .: .
NP_001 ---RIVSQNVGDVFPGIQDSGQD--TP--RGTPESGTSGQS--SDTESGYLQSHPQHSVD
120 130 140 150 160
180 190 200 210 220 230
pF1KE3 ELPPAGPGLAPKRPLETGPRDGVAVAAGAAVAAGTAPLKLPRVSYYGVPSLATLI-PGIQ
.. : . . . .: : . .::.:. . : ::: .. :: : : :
NP_001 RIYSALYACSMQNG--SGER---SFYSGAVVSHHETALGLPRDHHMEDPSWITRIHERSQ
170 180 190 200 210 220
240 250 260 270 280 290
pF1KE3 QM-------PYPQGERTSPGASSLPTTDSPTSYHNEEDEEDDEAYDTMVEEQYGQMYIKA
:: : : .: . : . . : ... ::: :: :::. ..
NP_001 QMERYLSTTPETTHCRKQPRPVRIQTLVG--NIHIKQEMEDD--YD-----YYGQQRVQI
230 240 250 260 270
300 310 320 330 340 350
pF1KE3 SGSYAVQEKPEPVPLESRSCVLIRRDLVALPASLISQIGYRCHPKLYSEGDPGEKLELVA
NP_001 LERNESEECTEDTDQAEGTESEPKGESFDSGVSSSIGTEPDSVEQQFGPGAARDSQAEPT
280 290 300 310 320 330
587 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 08:44:56 2016 done: Sun Nov 6 08:44:58 2016
Total Scan time: 12.670 Total Display time: 0.060
Function used was FASTA [36.3.4 Apr, 2011]