Result of FASTA (omim) for
pFN21AE3922
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3922, 909 aa
1>>>pF1KE3922 909 - 909 aa - 909 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.6429+/-0.000564; mu= 14.8092+/- 0.035
mean_var=209.7942+/-46.422, 0's: 0 Z-trim(113.0): 930 B-trim: 951 in 2/53
Lambda= 0.088548
statistics sampled from 20967 (22102) to 20967 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.606), E-opt: 0.2 (0.259), width: 16
Scan time: 11.560
The best scores are: opt bits E(85289)
NP_065822 (OMIM: 610876,616756) E3 ubiquitin-prote ( 909) 6109 795.2 0
NP_001308012 (OMIM: 610876,616756) E3 ubiquitin-pr ( 875) 5908 769.5 0
XP_016866604 (OMIM: 610876,616756) PREDICTED: E3 u ( 747) 5054 660.3 9.9e-189
XP_016866603 (OMIM: 610876,616756) PREDICTED: E3 u ( 831) 4953 647.4 8.1e-185
XP_016866602 (OMIM: 610876,616756) PREDICTED: E3 u ( 831) 4953 647.4 8.1e-185
NP_001308009 (OMIM: 610876,616756) E3 ubiquitin-pr ( 865) 4953 647.5 8.3e-185
XP_016866611 (OMIM: 610876,616756) PREDICTED: E3 u ( 715) 4749 621.3 5.2e-177
XP_016866610 (OMIM: 610876,616756) PREDICTED: E3 u ( 715) 4749 621.3 5.2e-177
XP_016866607 (OMIM: 610876,616756) PREDICTED: E3 u ( 741) 4749 621.3 5.3e-177
XP_016866608 (OMIM: 610876,616756) PREDICTED: E3 u ( 741) 4749 621.3 5.3e-177
NP_001308013 (OMIM: 610876,616756) E3 ubiquitin-pr ( 741) 4749 621.3 5.3e-177
XP_016866609 (OMIM: 610876,616756) PREDICTED: E3 u ( 741) 4749 621.3 5.3e-177
XP_016866605 (OMIM: 610876,616756) PREDICTED: E3 u ( 741) 4749 621.3 5.3e-177
XP_005260627 (OMIM: 606409,613385) PREDICTED: E3 u ( 692) 1013 144.0 2.4e-33
XP_011527381 (OMIM: 606409,613385) PREDICTED: E3 u ( 692) 1013 144.0 2.4e-33
XP_016883580 (OMIM: 606409,613385) PREDICTED: E3 u ( 752) 1013 144.1 2.5e-33
NP_001244067 (OMIM: 606409,613385) E3 ubiquitin-pr ( 752) 1013 144.1 2.5e-33
NP_001311127 (OMIM: 606409,613385) E3 ubiquitin-pr ( 862) 1013 144.1 2.7e-33
NP_113671 (OMIM: 606409,613385) E3 ubiquitin-prote ( 862) 1013 144.1 2.7e-33
XP_016883579 (OMIM: 606409,613385) PREDICTED: E3 u ( 900) 1013 144.2 2.8e-33
XP_016883578 (OMIM: 606409,613385) PREDICTED: E3 u ( 903) 1013 144.2 2.8e-33
NP_001311126 (OMIM: 606409,613385) E3 ubiquitin-pr ( 903) 1013 144.2 2.8e-33
NP_001244066 (OMIM: 606409,613385) E3 ubiquitin-pr ( 903) 1013 144.2 2.8e-33
XP_016884695 (OMIM: 300697,300706) PREDICTED: E3 u (4367) 1017 145.6 5e-33
XP_005262022 (OMIM: 300697,300706) PREDICTED: E3 u (4374) 1017 145.6 5e-33
NP_113584 (OMIM: 300697,300706) E3 ubiquitin-prote (4374) 1017 145.6 5e-33
XP_016884694 (OMIM: 300697,300706) PREDICTED: E3 u (4377) 1017 145.6 5e-33
XP_016884693 (OMIM: 300697,300706) PREDICTED: E3 u (4418) 1017 145.6 5e-33
XP_011529049 (OMIM: 300697,300706) PREDICTED: E3 u (4457) 1017 145.6 5e-33
XP_011529053 (OMIM: 300697,300706) PREDICTED: E3 u (4457) 1017 145.6 5e-33
XP_016884687 (OMIM: 300697,300706) PREDICTED: E3 u (4464) 1017 145.6 5e-33
XP_016884690 (OMIM: 300697,300706) PREDICTED: E3 u (4464) 1017 145.6 5e-33
XP_016884689 (OMIM: 300697,300706) PREDICTED: E3 u (4464) 1017 145.6 5e-33
XP_016884692 (OMIM: 300697,300706) PREDICTED: E3 u (4464) 1017 145.6 5e-33
XP_016884688 (OMIM: 300697,300706) PREDICTED: E3 u (4464) 1017 145.6 5e-33
XP_016884691 (OMIM: 300697,300706) PREDICTED: E3 u (4464) 1017 145.6 5e-33
XP_016884686 (OMIM: 300697,300706) PREDICTED: E3 u (4468) 1017 145.6 5e-33
XP_016884685 (OMIM: 300697,300706) PREDICTED: E3 u (4484) 1017 145.6 5e-33
XP_016884684 (OMIM: 300697,300706) PREDICTED: E3 u (4485) 1017 145.6 5e-33
XP_016884683 (OMIM: 300697,300706) PREDICTED: E3 u (4486) 1017 145.6 5e-33
XP_016884682 (OMIM: 300697,300706) PREDICTED: E3 u (4494) 1017 145.6 5e-33
XP_016884681 (OMIM: 300697,300706) PREDICTED: E3 u (4500) 1017 145.6 5e-33
XP_016884680 (OMIM: 300697,300706) PREDICTED: E3 u (4501) 1017 145.6 5e-33
XP_006722487 (OMIM: 606384) PREDICTED: E3 ubiquiti ( 790) 996 141.9 1.2e-32
XP_016881165 (OMIM: 606384) PREDICTED: E3 ubiquiti ( 856) 996 142.0 1.2e-32
XP_006722493 (OMIM: 606384) PREDICTED: E3 ubiquiti ( 872) 996 142.0 1.2e-32
XP_006722484 (OMIM: 606384) PREDICTED: E3 ubiquiti ( 940) 996 142.0 1.3e-32
XP_005266715 (OMIM: 606384) PREDICTED: E3 ubiquiti ( 960) 996 142.0 1.3e-32
XP_016881167 (OMIM: 606384) PREDICTED: E3 ubiquiti ( 973) 996 142.0 1.3e-32
XP_006722491 (OMIM: 606384) PREDICTED: E3 ubiquiti ( 993) 996 142.1 1.3e-32
>>NP_065822 (OMIM: 610876,616756) E3 ubiquitin-protein l (909 aa)
initn: 6109 init1: 6109 opt: 6109 Z-score: 4236.7 bits: 795.2 E(85289): 0
Smith-Waterman score: 6109; 99.8% identity (99.9% similar) in 909 aa overlap (1-909:1-909)
10 20 30 40 50 60
pF1KE3 MERAMEQLNRLTRSLRHARTVELPEDNETAVYTLMPMVMADQHRSVSELLSNSKFDVNYA
::::::::::::::::.:::::::::::::::::::::::::::::::::::::::::::
NP_065 MERAMEQLNRLTRSLRRARTVELPEDNETAVYTLMPMVMADQHRSVSELLSNSKFDVNYA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 FGRVKRSLLHIAANCGSVECLVLLLKKGANPNYQDISGCTPLHLAARNGQKKCMSKLLEY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 FGRVKRSLLHIAANCGSVECLVLLLKKGANPNYQDISGCTPLHLAARNGQKKCMSKLLEY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 SADVNICNNEGLTAIHWLAVNGRTELLHDLVQHVSDVDVEDAMGQTALHVACQNGHKTTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 SADVNICNNEGLTAIHWLAVNGRTELLHDLVQHVSDVDVEDAMGQTALHVACQNGHKTTV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 QCLLDSGADINRPNVSGATPLYFACSHGQRDTAQILLLRGAKYLPDKNGVTPLDLCVQGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 QCLLDSGADINRPNVSGATPLYFACSHGQRDTAQILLLRGAKYLPDKNGVTPLDLCVQGG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 YGETCEVLIQYHPRLFQTIIQMTQNEDLRENMLRQVLEHLSQQSESQYLKILTSLAEVAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 YGETCEVLIQYHPRLFQTIIQMTQNEDLRENMLRQVLEHLSQQSESQYLKILTSLAEVAT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 TNGHKLLSLSSNYDAQMKSLLRIVRMFCHVFRIGPSSPSNGIDMGYNGNKTPRSQVFKPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 TNGHKLLSLSSNYDAQMKSLLRIVRMFCHVFRIGPSSPSNGIDMGYNGNKTPRSQVFKPL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 ELLWHSLDEWLVLTATELMKNKRDSTEITSILLKQKGQDQDAASIPPFEPPGPGSYENLS
::::::::::::: ::::::::::::::::::::::::::::::::::::::::::::::
NP_065 ELLWHSLDEWLVLIATELMKNKRDSTEITSILLKQKGQDQDAASIPPFEPPGPGSYENLS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 TGTRESKPDALAGRQEASADCQDVISMTANRLSAVIQAFYMCCSCQMPPGMTSPRFIEFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 TGTRESKPDALAGRQEASADCQDVISMTANRLSAVIQAFYMCCSCQMPPGMTSPRFIEFV
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 CKHDEVLKCFVNRNPKIIFDHFHFLLECPELMSRFMHIIKAQPFKDRCEWFYEHLHSGQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 CKHDEVLKCFVNRNPKIIFDHFHFLLECPELMSRFMHIIKAQPFKDRCEWFYEHLHSGQP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 DSDMVHRPVNENDILLVHRDSIFRSSCEVVSKANCAKLKQGIAVRFHGEEGMGQGVVREW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 DSDMVHRPVNENDILLVHRDSIFRSSCEVVSKANCAKLKQGIAVRFHGEEGMGQGVVREW
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 FDILSNEIVNPDYALFTQSADGTTFQPNSNSYVNPDHLNYFRFAGQILGLALNHRQLVNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 FDILSNEIVNPDYALFTQSADGTTFQPNSNSYVNPDHLNYFRFAGQILGLALNHRQLVNI
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 YFTRSFYKHILGIPVNYQDVASIDPEYAKNLQWILDNDISDLGLELTFSVETDVFGAMEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 YFTRSFYKHILGIPVNYQDVASIDPEYAKNLQWILDNDISDLGLELTFSVETDVFGAMEE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 VPLKPGGGSILVTQNNKAEYVQLVTELRMTRAIQPQINAFLQGFHMFIPPSLIQLFDEYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 VPLKPGGGSILVTQNNKAEYVQLVTELRMTRAIQPQINAFLQGFHMFIPPSLIQLFDEYE
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE3 LELLLSGMPEIDVSDWIKNTEYTSGYEREDPVIQWFWEVVEDITQEERVLLLQFVTGSSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 LELLLSGMPEIDVSDWIKNTEYTSGYEREDPVIQWFWEVVEDITQEERVLLLQFVTGSSR
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE3 VPHGGFANIMGGSGLQNFTIAAVPYTPNLLPTSSTCINMLKLPEYPSKEILKDRLLVALH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 VPHGGFANIMGGSGLQNFTIAAVPYTPNLLPTSSTCINMLKLPEYPSKEILKDRLLVALH
850 860 870 880 890 900
pF1KE3 CGSYGYTMA
:::::::::
NP_065 CGSYGYTMA
>>NP_001308012 (OMIM: 610876,616756) E3 ubiquitin-protei (875 aa)
initn: 5908 init1: 5908 opt: 5908 Z-score: 4098.1 bits: 769.5 E(85289): 0
Smith-Waterman score: 5908; 99.9% identity (99.9% similar) in 875 aa overlap (35-909:1-875)
10 20 30 40 50 60
pF1KE3 MEQLNRLTRSLRHARTVELPEDNETAVYTLMPMVMADQHRSVSELLSNSKFDVNYAFGRV
::::::::::::::::::::::::::::::
NP_001 MPMVMADQHRSVSELLSNSKFDVNYAFGRV
10 20 30
70 80 90 100 110 120
pF1KE3 KRSLLHIAANCGSVECLVLLLKKGANPNYQDISGCTPLHLAARNGQKKCMSKLLEYSADV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KRSLLHIAANCGSVECLVLLLKKGANPNYQDISGCTPLHLAARNGQKKCMSKLLEYSADV
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE3 NICNNEGLTAIHWLAVNGRTELLHDLVQHVSDVDVEDAMGQTALHVACQNGHKTTVQCLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NICNNEGLTAIHWLAVNGRTELLHDLVQHVSDVDVEDAMGQTALHVACQNGHKTTVQCLL
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE3 DSGADINRPNVSGATPLYFACSHGQRDTAQILLLRGAKYLPDKNGVTPLDLCVQGGYGET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DSGADINRPNVSGATPLYFACSHGQRDTAQILLLRGAKYLPDKNGVTPLDLCVQGGYGET
160 170 180 190 200 210
250 260 270 280 290 300
pF1KE3 CEVLIQYHPRLFQTIIQMTQNEDLRENMLRQVLEHLSQQSESQYLKILTSLAEVATTNGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CEVLIQYHPRLFQTIIQMTQNEDLRENMLRQVLEHLSQQSESQYLKILTSLAEVATTNGH
220 230 240 250 260 270
310 320 330 340 350 360
pF1KE3 KLLSLSSNYDAQMKSLLRIVRMFCHVFRIGPSSPSNGIDMGYNGNKTPRSQVFKPLELLW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KLLSLSSNYDAQMKSLLRIVRMFCHVFRIGPSSPSNGIDMGYNGNKTPRSQVFKPLELLW
280 290 300 310 320 330
370 380 390 400 410 420
pF1KE3 HSLDEWLVLTATELMKNKRDSTEITSILLKQKGQDQDAASIPPFEPPGPGSYENLSTGTR
::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HSLDEWLVLIATELMKNKRDSTEITSILLKQKGQDQDAASIPPFEPPGPGSYENLSTGTR
340 350 360 370 380 390
430 440 450 460 470 480
pF1KE3 ESKPDALAGRQEASADCQDVISMTANRLSAVIQAFYMCCSCQMPPGMTSPRFIEFVCKHD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESKPDALAGRQEASADCQDVISMTANRLSAVIQAFYMCCSCQMPPGMTSPRFIEFVCKHD
400 410 420 430 440 450
490 500 510 520 530 540
pF1KE3 EVLKCFVNRNPKIIFDHFHFLLECPELMSRFMHIIKAQPFKDRCEWFYEHLHSGQPDSDM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EVLKCFVNRNPKIIFDHFHFLLECPELMSRFMHIIKAQPFKDRCEWFYEHLHSGQPDSDM
460 470 480 490 500 510
550 560 570 580 590 600
pF1KE3 VHRPVNENDILLVHRDSIFRSSCEVVSKANCAKLKQGIAVRFHGEEGMGQGVVREWFDIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VHRPVNENDILLVHRDSIFRSSCEVVSKANCAKLKQGIAVRFHGEEGMGQGVVREWFDIL
520 530 540 550 560 570
610 620 630 640 650 660
pF1KE3 SNEIVNPDYALFTQSADGTTFQPNSNSYVNPDHLNYFRFAGQILGLALNHRQLVNIYFTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SNEIVNPDYALFTQSADGTTFQPNSNSYVNPDHLNYFRFAGQILGLALNHRQLVNIYFTR
580 590 600 610 620 630
670 680 690 700 710 720
pF1KE3 SFYKHILGIPVNYQDVASIDPEYAKNLQWILDNDISDLGLELTFSVETDVFGAMEEVPLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SFYKHILGIPVNYQDVASIDPEYAKNLQWILDNDISDLGLELTFSVETDVFGAMEEVPLK
640 650 660 670 680 690
730 740 750 760 770 780
pF1KE3 PGGGSILVTQNNKAEYVQLVTELRMTRAIQPQINAFLQGFHMFIPPSLIQLFDEYELELL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PGGGSILVTQNNKAEYVQLVTELRMTRAIQPQINAFLQGFHMFIPPSLIQLFDEYELELL
700 710 720 730 740 750
790 800 810 820 830 840
pF1KE3 LSGMPEIDVSDWIKNTEYTSGYEREDPVIQWFWEVVEDITQEERVLLLQFVTGSSRVPHG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSGMPEIDVSDWIKNTEYTSGYEREDPVIQWFWEVVEDITQEERVLLLQFVTGSSRVPHG
760 770 780 790 800 810
850 860 870 880 890 900
pF1KE3 GFANIMGGSGLQNFTIAAVPYTPNLLPTSSTCINMLKLPEYPSKEILKDRLLVALHCGSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GFANIMGGSGLQNFTIAAVPYTPNLLPTSSTCINMLKLPEYPSKEILKDRLLVALHCGSY
820 830 840 850 860 870
pF1KE3 GYTMA
:::::
NP_001 GYTMA
>>XP_016866604 (OMIM: 610876,616756) PREDICTED: E3 ubiqu (747 aa)
initn: 5054 init1: 5054 opt: 5054 Z-score: 3509.3 bits: 660.3 E(85289): 9.9e-189
Smith-Waterman score: 5054; 99.9% identity (99.9% similar) in 747 aa overlap (163-909:1-747)
140 150 160 170 180 190
pF1KE3 TAIHWLAVNGRTELLHDLVQHVSDVDVEDAMGQTALHVACQNGHKTTVQCLLDSGADINR
::::::::::::::::::::::::::::::
XP_016 MGQTALHVACQNGHKTTVQCLLDSGADINR
10 20 30
200 210 220 230 240 250
pF1KE3 PNVSGATPLYFACSHGQRDTAQILLLRGAKYLPDKNGVTPLDLCVQGGYGETCEVLIQYH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PNVSGATPLYFACSHGQRDTAQILLLRGAKYLPDKNGVTPLDLCVQGGYGETCEVLIQYH
40 50 60 70 80 90
260 270 280 290 300 310
pF1KE3 PRLFQTIIQMTQNEDLRENMLRQVLEHLSQQSESQYLKILTSLAEVATTNGHKLLSLSSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PRLFQTIIQMTQNEDLRENMLRQVLEHLSQQSESQYLKILTSLAEVATTNGHKLLSLSSN
100 110 120 130 140 150
320 330 340 350 360 370
pF1KE3 YDAQMKSLLRIVRMFCHVFRIGPSSPSNGIDMGYNGNKTPRSQVFKPLELLWHSLDEWLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YDAQMKSLLRIVRMFCHVFRIGPSSPSNGIDMGYNGNKTPRSQVFKPLELLWHSLDEWLV
160 170 180 190 200 210
380 390 400 410 420 430
pF1KE3 LTATELMKNKRDSTEITSILLKQKGQDQDAASIPPFEPPGPGSYENLSTGTRESKPDALA
: ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LIATELMKNKRDSTEITSILLKQKGQDQDAASIPPFEPPGPGSYENLSTGTRESKPDALA
220 230 240 250 260 270
440 450 460 470 480 490
pF1KE3 GRQEASADCQDVISMTANRLSAVIQAFYMCCSCQMPPGMTSPRFIEFVCKHDEVLKCFVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GRQEASADCQDVISMTANRLSAVIQAFYMCCSCQMPPGMTSPRFIEFVCKHDEVLKCFVN
280 290 300 310 320 330
500 510 520 530 540 550
pF1KE3 RNPKIIFDHFHFLLECPELMSRFMHIIKAQPFKDRCEWFYEHLHSGQPDSDMVHRPVNEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RNPKIIFDHFHFLLECPELMSRFMHIIKAQPFKDRCEWFYEHLHSGQPDSDMVHRPVNEN
340 350 360 370 380 390
560 570 580 590 600 610
pF1KE3 DILLVHRDSIFRSSCEVVSKANCAKLKQGIAVRFHGEEGMGQGVVREWFDILSNEIVNPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DILLVHRDSIFRSSCEVVSKANCAKLKQGIAVRFHGEEGMGQGVVREWFDILSNEIVNPD
400 410 420 430 440 450
620 630 640 650 660 670
pF1KE3 YALFTQSADGTTFQPNSNSYVNPDHLNYFRFAGQILGLALNHRQLVNIYFTRSFYKHILG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YALFTQSADGTTFQPNSNSYVNPDHLNYFRFAGQILGLALNHRQLVNIYFTRSFYKHILG
460 470 480 490 500 510
680 690 700 710 720 730
pF1KE3 IPVNYQDVASIDPEYAKNLQWILDNDISDLGLELTFSVETDVFGAMEEVPLKPGGGSILV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IPVNYQDVASIDPEYAKNLQWILDNDISDLGLELTFSVETDVFGAMEEVPLKPGGGSILV
520 530 540 550 560 570
740 750 760 770 780 790
pF1KE3 TQNNKAEYVQLVTELRMTRAIQPQINAFLQGFHMFIPPSLIQLFDEYELELLLSGMPEID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TQNNKAEYVQLVTELRMTRAIQPQINAFLQGFHMFIPPSLIQLFDEYELELLLSGMPEID
580 590 600 610 620 630
800 810 820 830 840 850
pF1KE3 VSDWIKNTEYTSGYEREDPVIQWFWEVVEDITQEERVLLLQFVTGSSRVPHGGFANIMGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VSDWIKNTEYTSGYEREDPVIQWFWEVVEDITQEERVLLLQFVTGSSRVPHGGFANIMGG
640 650 660 670 680 690
860 870 880 890 900
pF1KE3 SGLQNFTIAAVPYTPNLLPTSSTCINMLKLPEYPSKEILKDRLLVALHCGSYGYTMA
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SGLQNFTIAAVPYTPNLLPTSSTCINMLKLPEYPSKEILKDRLLVALHCGSYGYTMA
700 710 720 730 740
>>XP_016866603 (OMIM: 610876,616756) PREDICTED: E3 ubiqu (831 aa)
initn: 4948 init1: 4948 opt: 4953 Z-score: 3439.0 bits: 647.4 E(85289): 8.1e-185
Smith-Waterman score: 5509; 94.9% identity (94.9% similar) in 875 aa overlap (35-909:1-831)
10 20 30 40 50 60
pF1KE3 MEQLNRLTRSLRHARTVELPEDNETAVYTLMPMVMADQHRSVSELLSNSKFDVNYAFGRV
::::::::::::::::::::::::::::::
XP_016 MPMVMADQHRSVSELLSNSKFDVNYAFGRV
10 20 30
70 80 90 100 110 120
pF1KE3 KRSLLHIAANCGSVECLVLLLKKGANPNYQDISGCTPLHLAARNGQKKCMSKLLEYSADV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KRSLLHIAANCGSVECLVLLLKKGANPNYQDISGCTPLHLAARNGQKKCMSKLLEYSADV
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE3 NICNNEGLTAIHWLAVNGRTELLHDLVQHVSDVDVEDAMGQTALHVACQNGHKTTVQCLL
:::::::::: ::::::
XP_016 NICNNEGLTA--------------------------------------------TVQCLL
100
190 200 210 220 230 240
pF1KE3 DSGADINRPNVSGATPLYFACSHGQRDTAQILLLRGAKYLPDKNGVTPLDLCVQGGYGET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DSGADINRPNVSGATPLYFACSHGQRDTAQILLLRGAKYLPDKNGVTPLDLCVQGGYGET
110 120 130 140 150 160
250 260 270 280 290 300
pF1KE3 CEVLIQYHPRLFQTIIQMTQNEDLRENMLRQVLEHLSQQSESQYLKILTSLAEVATTNGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CEVLIQYHPRLFQTIIQMTQNEDLRENMLRQVLEHLSQQSESQYLKILTSLAEVATTNGH
170 180 190 200 210 220
310 320 330 340 350 360
pF1KE3 KLLSLSSNYDAQMKSLLRIVRMFCHVFRIGPSSPSNGIDMGYNGNKTPRSQVFKPLELLW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLLSLSSNYDAQMKSLLRIVRMFCHVFRIGPSSPSNGIDMGYNGNKTPRSQVFKPLELLW
230 240 250 260 270 280
370 380 390 400 410 420
pF1KE3 HSLDEWLVLTATELMKNKRDSTEITSILLKQKGQDQDAASIPPFEPPGPGSYENLSTGTR
::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HSLDEWLVLIATELMKNKRDSTEITSILLKQKGQDQDAASIPPFEPPGPGSYENLSTGTR
290 300 310 320 330 340
430 440 450 460 470 480
pF1KE3 ESKPDALAGRQEASADCQDVISMTANRLSAVIQAFYMCCSCQMPPGMTSPRFIEFVCKHD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESKPDALAGRQEASADCQDVISMTANRLSAVIQAFYMCCSCQMPPGMTSPRFIEFVCKHD
350 360 370 380 390 400
490 500 510 520 530 540
pF1KE3 EVLKCFVNRNPKIIFDHFHFLLECPELMSRFMHIIKAQPFKDRCEWFYEHLHSGQPDSDM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EVLKCFVNRNPKIIFDHFHFLLECPELMSRFMHIIKAQPFKDRCEWFYEHLHSGQPDSDM
410 420 430 440 450 460
550 560 570 580 590 600
pF1KE3 VHRPVNENDILLVHRDSIFRSSCEVVSKANCAKLKQGIAVRFHGEEGMGQGVVREWFDIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VHRPVNENDILLVHRDSIFRSSCEVVSKANCAKLKQGIAVRFHGEEGMGQGVVREWFDIL
470 480 490 500 510 520
610 620 630 640 650 660
pF1KE3 SNEIVNPDYALFTQSADGTTFQPNSNSYVNPDHLNYFRFAGQILGLALNHRQLVNIYFTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SNEIVNPDYALFTQSADGTTFQPNSNSYVNPDHLNYFRFAGQILGLALNHRQLVNIYFTR
530 540 550 560 570 580
670 680 690 700 710 720
pF1KE3 SFYKHILGIPVNYQDVASIDPEYAKNLQWILDNDISDLGLELTFSVETDVFGAMEEVPLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SFYKHILGIPVNYQDVASIDPEYAKNLQWILDNDISDLGLELTFSVETDVFGAMEEVPLK
590 600 610 620 630 640
730 740 750 760 770 780
pF1KE3 PGGGSILVTQNNKAEYVQLVTELRMTRAIQPQINAFLQGFHMFIPPSLIQLFDEYELELL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGGGSILVTQNNKAEYVQLVTELRMTRAIQPQINAFLQGFHMFIPPSLIQLFDEYELELL
650 660 670 680 690 700
790 800 810 820 830 840
pF1KE3 LSGMPEIDVSDWIKNTEYTSGYEREDPVIQWFWEVVEDITQEERVLLLQFVTGSSRVPHG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSGMPEIDVSDWIKNTEYTSGYEREDPVIQWFWEVVEDITQEERVLLLQFVTGSSRVPHG
710 720 730 740 750 760
850 860 870 880 890 900
pF1KE3 GFANIMGGSGLQNFTIAAVPYTPNLLPTSSTCINMLKLPEYPSKEILKDRLLVALHCGSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GFANIMGGSGLQNFTIAAVPYTPNLLPTSSTCINMLKLPEYPSKEILKDRLLVALHCGSY
770 780 790 800 810 820
pF1KE3 GYTMA
:::::
XP_016 GYTMA
830
>>XP_016866602 (OMIM: 610876,616756) PREDICTED: E3 ubiqu (831 aa)
initn: 4948 init1: 4948 opt: 4953 Z-score: 3439.0 bits: 647.4 E(85289): 8.1e-185
Smith-Waterman score: 5509; 94.9% identity (94.9% similar) in 875 aa overlap (35-909:1-831)
10 20 30 40 50 60
pF1KE3 MEQLNRLTRSLRHARTVELPEDNETAVYTLMPMVMADQHRSVSELLSNSKFDVNYAFGRV
::::::::::::::::::::::::::::::
XP_016 MPMVMADQHRSVSELLSNSKFDVNYAFGRV
10 20 30
70 80 90 100 110 120
pF1KE3 KRSLLHIAANCGSVECLVLLLKKGANPNYQDISGCTPLHLAARNGQKKCMSKLLEYSADV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KRSLLHIAANCGSVECLVLLLKKGANPNYQDISGCTPLHLAARNGQKKCMSKLLEYSADV
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE3 NICNNEGLTAIHWLAVNGRTELLHDLVQHVSDVDVEDAMGQTALHVACQNGHKTTVQCLL
:::::::::: ::::::
XP_016 NICNNEGLTA--------------------------------------------TVQCLL
100
190 200 210 220 230 240
pF1KE3 DSGADINRPNVSGATPLYFACSHGQRDTAQILLLRGAKYLPDKNGVTPLDLCVQGGYGET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DSGADINRPNVSGATPLYFACSHGQRDTAQILLLRGAKYLPDKNGVTPLDLCVQGGYGET
110 120 130 140 150 160
250 260 270 280 290 300
pF1KE3 CEVLIQYHPRLFQTIIQMTQNEDLRENMLRQVLEHLSQQSESQYLKILTSLAEVATTNGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CEVLIQYHPRLFQTIIQMTQNEDLRENMLRQVLEHLSQQSESQYLKILTSLAEVATTNGH
170 180 190 200 210 220
310 320 330 340 350 360
pF1KE3 KLLSLSSNYDAQMKSLLRIVRMFCHVFRIGPSSPSNGIDMGYNGNKTPRSQVFKPLELLW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLLSLSSNYDAQMKSLLRIVRMFCHVFRIGPSSPSNGIDMGYNGNKTPRSQVFKPLELLW
230 240 250 260 270 280
370 380 390 400 410 420
pF1KE3 HSLDEWLVLTATELMKNKRDSTEITSILLKQKGQDQDAASIPPFEPPGPGSYENLSTGTR
::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HSLDEWLVLIATELMKNKRDSTEITSILLKQKGQDQDAASIPPFEPPGPGSYENLSTGTR
290 300 310 320 330 340
430 440 450 460 470 480
pF1KE3 ESKPDALAGRQEASADCQDVISMTANRLSAVIQAFYMCCSCQMPPGMTSPRFIEFVCKHD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESKPDALAGRQEASADCQDVISMTANRLSAVIQAFYMCCSCQMPPGMTSPRFIEFVCKHD
350 360 370 380 390 400
490 500 510 520 530 540
pF1KE3 EVLKCFVNRNPKIIFDHFHFLLECPELMSRFMHIIKAQPFKDRCEWFYEHLHSGQPDSDM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EVLKCFVNRNPKIIFDHFHFLLECPELMSRFMHIIKAQPFKDRCEWFYEHLHSGQPDSDM
410 420 430 440 450 460
550 560 570 580 590 600
pF1KE3 VHRPVNENDILLVHRDSIFRSSCEVVSKANCAKLKQGIAVRFHGEEGMGQGVVREWFDIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VHRPVNENDILLVHRDSIFRSSCEVVSKANCAKLKQGIAVRFHGEEGMGQGVVREWFDIL
470 480 490 500 510 520
610 620 630 640 650 660
pF1KE3 SNEIVNPDYALFTQSADGTTFQPNSNSYVNPDHLNYFRFAGQILGLALNHRQLVNIYFTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SNEIVNPDYALFTQSADGTTFQPNSNSYVNPDHLNYFRFAGQILGLALNHRQLVNIYFTR
530 540 550 560 570 580
670 680 690 700 710 720
pF1KE3 SFYKHILGIPVNYQDVASIDPEYAKNLQWILDNDISDLGLELTFSVETDVFGAMEEVPLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SFYKHILGIPVNYQDVASIDPEYAKNLQWILDNDISDLGLELTFSVETDVFGAMEEVPLK
590 600 610 620 630 640
730 740 750 760 770 780
pF1KE3 PGGGSILVTQNNKAEYVQLVTELRMTRAIQPQINAFLQGFHMFIPPSLIQLFDEYELELL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGGGSILVTQNNKAEYVQLVTELRMTRAIQPQINAFLQGFHMFIPPSLIQLFDEYELELL
650 660 670 680 690 700
790 800 810 820 830 840
pF1KE3 LSGMPEIDVSDWIKNTEYTSGYEREDPVIQWFWEVVEDITQEERVLLLQFVTGSSRVPHG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSGMPEIDVSDWIKNTEYTSGYEREDPVIQWFWEVVEDITQEERVLLLQFVTGSSRVPHG
710 720 730 740 750 760
850 860 870 880 890 900
pF1KE3 GFANIMGGSGLQNFTIAAVPYTPNLLPTSSTCINMLKLPEYPSKEILKDRLLVALHCGSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GFANIMGGSGLQNFTIAAVPYTPNLLPTSSTCINMLKLPEYPSKEILKDRLLVALHCGSY
770 780 790 800 810 820
pF1KE3 GYTMA
:::::
XP_016 GYTMA
830
>>NP_001308009 (OMIM: 610876,616756) E3 ubiquitin-protei (865 aa)
initn: 4948 init1: 4948 opt: 4953 Z-score: 3438.9 bits: 647.5 E(85289): 8.3e-185
Smith-Waterman score: 5710; 94.9% identity (95.0% similar) in 909 aa overlap (1-909:1-865)
10 20 30 40 50 60
pF1KE3 MERAMEQLNRLTRSLRHARTVELPEDNETAVYTLMPMVMADQHRSVSELLSNSKFDVNYA
::::::::::::::::.:::::::::::::::::::::::::::::::::::::::::::
NP_001 MERAMEQLNRLTRSLRRARTVELPEDNETAVYTLMPMVMADQHRSVSELLSNSKFDVNYA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 FGRVKRSLLHIAANCGSVECLVLLLKKGANPNYQDISGCTPLHLAARNGQKKCMSKLLEY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FGRVKRSLLHIAANCGSVECLVLLLKKGANPNYQDISGCTPLHLAARNGQKKCMSKLLEY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 SADVNICNNEGLTAIHWLAVNGRTELLHDLVQHVSDVDVEDAMGQTALHVACQNGHKTTV
:::::::::::::: ::
NP_001 SADVNICNNEGLTA--------------------------------------------TV
130
190 200 210 220 230 240
pF1KE3 QCLLDSGADINRPNVSGATPLYFACSHGQRDTAQILLLRGAKYLPDKNGVTPLDLCVQGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QCLLDSGADINRPNVSGATPLYFACSHGQRDTAQILLLRGAKYLPDKNGVTPLDLCVQGG
140 150 160 170 180 190
250 260 270 280 290 300
pF1KE3 YGETCEVLIQYHPRLFQTIIQMTQNEDLRENMLRQVLEHLSQQSESQYLKILTSLAEVAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YGETCEVLIQYHPRLFQTIIQMTQNEDLRENMLRQVLEHLSQQSESQYLKILTSLAEVAT
200 210 220 230 240 250
310 320 330 340 350 360
pF1KE3 TNGHKLLSLSSNYDAQMKSLLRIVRMFCHVFRIGPSSPSNGIDMGYNGNKTPRSQVFKPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TNGHKLLSLSSNYDAQMKSLLRIVRMFCHVFRIGPSSPSNGIDMGYNGNKTPRSQVFKPL
260 270 280 290 300 310
370 380 390 400 410 420
pF1KE3 ELLWHSLDEWLVLTATELMKNKRDSTEITSILLKQKGQDQDAASIPPFEPPGPGSYENLS
::::::::::::: ::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELLWHSLDEWLVLIATELMKNKRDSTEITSILLKQKGQDQDAASIPPFEPPGPGSYENLS
320 330 340 350 360 370
430 440 450 460 470 480
pF1KE3 TGTRESKPDALAGRQEASADCQDVISMTANRLSAVIQAFYMCCSCQMPPGMTSPRFIEFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TGTRESKPDALAGRQEASADCQDVISMTANRLSAVIQAFYMCCSCQMPPGMTSPRFIEFV
380 390 400 410 420 430
490 500 510 520 530 540
pF1KE3 CKHDEVLKCFVNRNPKIIFDHFHFLLECPELMSRFMHIIKAQPFKDRCEWFYEHLHSGQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CKHDEVLKCFVNRNPKIIFDHFHFLLECPELMSRFMHIIKAQPFKDRCEWFYEHLHSGQP
440 450 460 470 480 490
550 560 570 580 590 600
pF1KE3 DSDMVHRPVNENDILLVHRDSIFRSSCEVVSKANCAKLKQGIAVRFHGEEGMGQGVVREW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DSDMVHRPVNENDILLVHRDSIFRSSCEVVSKANCAKLKQGIAVRFHGEEGMGQGVVREW
500 510 520 530 540 550
610 620 630 640 650 660
pF1KE3 FDILSNEIVNPDYALFTQSADGTTFQPNSNSYVNPDHLNYFRFAGQILGLALNHRQLVNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FDILSNEIVNPDYALFTQSADGTTFQPNSNSYVNPDHLNYFRFAGQILGLALNHRQLVNI
560 570 580 590 600 610
670 680 690 700 710 720
pF1KE3 YFTRSFYKHILGIPVNYQDVASIDPEYAKNLQWILDNDISDLGLELTFSVETDVFGAMEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YFTRSFYKHILGIPVNYQDVASIDPEYAKNLQWILDNDISDLGLELTFSVETDVFGAMEE
620 630 640 650 660 670
730 740 750 760 770 780
pF1KE3 VPLKPGGGSILVTQNNKAEYVQLVTELRMTRAIQPQINAFLQGFHMFIPPSLIQLFDEYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VPLKPGGGSILVTQNNKAEYVQLVTELRMTRAIQPQINAFLQGFHMFIPPSLIQLFDEYE
680 690 700 710 720 730
790 800 810 820 830 840
pF1KE3 LELLLSGMPEIDVSDWIKNTEYTSGYEREDPVIQWFWEVVEDITQEERVLLLQFVTGSSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LELLLSGMPEIDVSDWIKNTEYTSGYEREDPVIQWFWEVVEDITQEERVLLLQFVTGSSR
740 750 760 770 780 790
850 860 870 880 890 900
pF1KE3 VPHGGFANIMGGSGLQNFTIAAVPYTPNLLPTSSTCINMLKLPEYPSKEILKDRLLVALH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VPHGGFANIMGGSGLQNFTIAAVPYTPNLLPTSSTCINMLKLPEYPSKEILKDRLLVALH
800 810 820 830 840 850
pF1KE3 CGSYGYTMA
:::::::::
NP_001 CGSYGYTMA
860
>>XP_016866611 (OMIM: 610876,616756) PREDICTED: E3 ubiqu (715 aa)
initn: 4749 init1: 4749 opt: 4749 Z-score: 3298.9 bits: 621.3 E(85289): 5.2e-177
Smith-Waterman score: 4749; 99.9% identity (99.9% similar) in 703 aa overlap (207-909:13-715)
180 190 200 210 220 230
pF1KE3 KTTVQCLLDSGADINRPNVSGATPLYFACSHGQRDTAQILLLRGAKYLPDKNGVTPLDLC
::::::::::::::::::::::::::::::
XP_016 MSTFVIMKALQHHGQRDTAQILLLRGAKYLPDKNGVTPLDLC
10 20 30 40
240 250 260 270 280 290
pF1KE3 VQGGYGETCEVLIQYHPRLFQTIIQMTQNEDLRENMLRQVLEHLSQQSESQYLKILTSLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VQGGYGETCEVLIQYHPRLFQTIIQMTQNEDLRENMLRQVLEHLSQQSESQYLKILTSLA
50 60 70 80 90 100
300 310 320 330 340 350
pF1KE3 EVATTNGHKLLSLSSNYDAQMKSLLRIVRMFCHVFRIGPSSPSNGIDMGYNGNKTPRSQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EVATTNGHKLLSLSSNYDAQMKSLLRIVRMFCHVFRIGPSSPSNGIDMGYNGNKTPRSQV
110 120 130 140 150 160
360 370 380 390 400 410
pF1KE3 FKPLELLWHSLDEWLVLTATELMKNKRDSTEITSILLKQKGQDQDAASIPPFEPPGPGSY
::::::::::::::::: ::::::::::::::::::::::::::::::::::::::::::
XP_016 FKPLELLWHSLDEWLVLIATELMKNKRDSTEITSILLKQKGQDQDAASIPPFEPPGPGSY
170 180 190 200 210 220
420 430 440 450 460 470
pF1KE3 ENLSTGTRESKPDALAGRQEASADCQDVISMTANRLSAVIQAFYMCCSCQMPPGMTSPRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ENLSTGTRESKPDALAGRQEASADCQDVISMTANRLSAVIQAFYMCCSCQMPPGMTSPRF
230 240 250 260 270 280
480 490 500 510 520 530
pF1KE3 IEFVCKHDEVLKCFVNRNPKIIFDHFHFLLECPELMSRFMHIIKAQPFKDRCEWFYEHLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IEFVCKHDEVLKCFVNRNPKIIFDHFHFLLECPELMSRFMHIIKAQPFKDRCEWFYEHLH
290 300 310 320 330 340
540 550 560 570 580 590
pF1KE3 SGQPDSDMVHRPVNENDILLVHRDSIFRSSCEVVSKANCAKLKQGIAVRFHGEEGMGQGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SGQPDSDMVHRPVNENDILLVHRDSIFRSSCEVVSKANCAKLKQGIAVRFHGEEGMGQGV
350 360 370 380 390 400
600 610 620 630 640 650
pF1KE3 VREWFDILSNEIVNPDYALFTQSADGTTFQPNSNSYVNPDHLNYFRFAGQILGLALNHRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VREWFDILSNEIVNPDYALFTQSADGTTFQPNSNSYVNPDHLNYFRFAGQILGLALNHRQ
410 420 430 440 450 460
660 670 680 690 700 710
pF1KE3 LVNIYFTRSFYKHILGIPVNYQDVASIDPEYAKNLQWILDNDISDLGLELTFSVETDVFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LVNIYFTRSFYKHILGIPVNYQDVASIDPEYAKNLQWILDNDISDLGLELTFSVETDVFG
470 480 490 500 510 520
720 730 740 750 760 770
pF1KE3 AMEEVPLKPGGGSILVTQNNKAEYVQLVTELRMTRAIQPQINAFLQGFHMFIPPSLIQLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AMEEVPLKPGGGSILVTQNNKAEYVQLVTELRMTRAIQPQINAFLQGFHMFIPPSLIQLF
530 540 550 560 570 580
780 790 800 810 820 830
pF1KE3 DEYELELLLSGMPEIDVSDWIKNTEYTSGYEREDPVIQWFWEVVEDITQEERVLLLQFVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DEYELELLLSGMPEIDVSDWIKNTEYTSGYEREDPVIQWFWEVVEDITQEERVLLLQFVT
590 600 610 620 630 640
840 850 860 870 880 890
pF1KE3 GSSRVPHGGFANIMGGSGLQNFTIAAVPYTPNLLPTSSTCINMLKLPEYPSKEILKDRLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSSRVPHGGFANIMGGSGLQNFTIAAVPYTPNLLPTSSTCINMLKLPEYPSKEILKDRLL
650 660 670 680 690 700
900
pF1KE3 VALHCGSYGYTMA
:::::::::::::
XP_016 VALHCGSYGYTMA
710
>>XP_016866610 (OMIM: 610876,616756) PREDICTED: E3 ubiqu (715 aa)
initn: 4749 init1: 4749 opt: 4749 Z-score: 3298.9 bits: 621.3 E(85289): 5.2e-177
Smith-Waterman score: 4749; 99.9% identity (99.9% similar) in 703 aa overlap (207-909:13-715)
180 190 200 210 220 230
pF1KE3 KTTVQCLLDSGADINRPNVSGATPLYFACSHGQRDTAQILLLRGAKYLPDKNGVTPLDLC
::::::::::::::::::::::::::::::
XP_016 MSTFVIMKALQHHGQRDTAQILLLRGAKYLPDKNGVTPLDLC
10 20 30 40
240 250 260 270 280 290
pF1KE3 VQGGYGETCEVLIQYHPRLFQTIIQMTQNEDLRENMLRQVLEHLSQQSESQYLKILTSLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VQGGYGETCEVLIQYHPRLFQTIIQMTQNEDLRENMLRQVLEHLSQQSESQYLKILTSLA
50 60 70 80 90 100
300 310 320 330 340 350
pF1KE3 EVATTNGHKLLSLSSNYDAQMKSLLRIVRMFCHVFRIGPSSPSNGIDMGYNGNKTPRSQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EVATTNGHKLLSLSSNYDAQMKSLLRIVRMFCHVFRIGPSSPSNGIDMGYNGNKTPRSQV
110 120 130 140 150 160
360 370 380 390 400 410
pF1KE3 FKPLELLWHSLDEWLVLTATELMKNKRDSTEITSILLKQKGQDQDAASIPPFEPPGPGSY
::::::::::::::::: ::::::::::::::::::::::::::::::::::::::::::
XP_016 FKPLELLWHSLDEWLVLIATELMKNKRDSTEITSILLKQKGQDQDAASIPPFEPPGPGSY
170 180 190 200 210 220
420 430 440 450 460 470
pF1KE3 ENLSTGTRESKPDALAGRQEASADCQDVISMTANRLSAVIQAFYMCCSCQMPPGMTSPRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ENLSTGTRESKPDALAGRQEASADCQDVISMTANRLSAVIQAFYMCCSCQMPPGMTSPRF
230 240 250 260 270 280
480 490 500 510 520 530
pF1KE3 IEFVCKHDEVLKCFVNRNPKIIFDHFHFLLECPELMSRFMHIIKAQPFKDRCEWFYEHLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IEFVCKHDEVLKCFVNRNPKIIFDHFHFLLECPELMSRFMHIIKAQPFKDRCEWFYEHLH
290 300 310 320 330 340
540 550 560 570 580 590
pF1KE3 SGQPDSDMVHRPVNENDILLVHRDSIFRSSCEVVSKANCAKLKQGIAVRFHGEEGMGQGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SGQPDSDMVHRPVNENDILLVHRDSIFRSSCEVVSKANCAKLKQGIAVRFHGEEGMGQGV
350 360 370 380 390 400
600 610 620 630 640 650
pF1KE3 VREWFDILSNEIVNPDYALFTQSADGTTFQPNSNSYVNPDHLNYFRFAGQILGLALNHRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VREWFDILSNEIVNPDYALFTQSADGTTFQPNSNSYVNPDHLNYFRFAGQILGLALNHRQ
410 420 430 440 450 460
660 670 680 690 700 710
pF1KE3 LVNIYFTRSFYKHILGIPVNYQDVASIDPEYAKNLQWILDNDISDLGLELTFSVETDVFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LVNIYFTRSFYKHILGIPVNYQDVASIDPEYAKNLQWILDNDISDLGLELTFSVETDVFG
470 480 490 500 510 520
720 730 740 750 760 770
pF1KE3 AMEEVPLKPGGGSILVTQNNKAEYVQLVTELRMTRAIQPQINAFLQGFHMFIPPSLIQLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AMEEVPLKPGGGSILVTQNNKAEYVQLVTELRMTRAIQPQINAFLQGFHMFIPPSLIQLF
530 540 550 560 570 580
780 790 800 810 820 830
pF1KE3 DEYELELLLSGMPEIDVSDWIKNTEYTSGYEREDPVIQWFWEVVEDITQEERVLLLQFVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DEYELELLLSGMPEIDVSDWIKNTEYTSGYEREDPVIQWFWEVVEDITQEERVLLLQFVT
590 600 610 620 630 640
840 850 860 870 880 890
pF1KE3 GSSRVPHGGFANIMGGSGLQNFTIAAVPYTPNLLPTSSTCINMLKLPEYPSKEILKDRLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSSRVPHGGFANIMGGSGLQNFTIAAVPYTPNLLPTSSTCINMLKLPEYPSKEILKDRLL
650 660 670 680 690 700
900
pF1KE3 VALHCGSYGYTMA
:::::::::::::
XP_016 VALHCGSYGYTMA
710
>>XP_016866607 (OMIM: 610876,616756) PREDICTED: E3 ubiqu (741 aa)
initn: 4749 init1: 4749 opt: 4749 Z-score: 3298.7 bits: 621.3 E(85289): 5.3e-177
Smith-Waterman score: 4749; 99.9% identity (99.9% similar) in 703 aa overlap (207-909:39-741)
180 190 200 210 220 230
pF1KE3 KTTVQCLLDSGADINRPNVSGATPLYFACSHGQRDTAQILLLRGAKYLPDKNGVTPLDLC
::::::::::::::::::::::::::::::
XP_016 TLCSMSVMLMLRMPWGRQHCMLPARTVTRRHGQRDTAQILLLRGAKYLPDKNGVTPLDLC
10 20 30 40 50 60
240 250 260 270 280 290
pF1KE3 VQGGYGETCEVLIQYHPRLFQTIIQMTQNEDLRENMLRQVLEHLSQQSESQYLKILTSLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VQGGYGETCEVLIQYHPRLFQTIIQMTQNEDLRENMLRQVLEHLSQQSESQYLKILTSLA
70 80 90 100 110 120
300 310 320 330 340 350
pF1KE3 EVATTNGHKLLSLSSNYDAQMKSLLRIVRMFCHVFRIGPSSPSNGIDMGYNGNKTPRSQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EVATTNGHKLLSLSSNYDAQMKSLLRIVRMFCHVFRIGPSSPSNGIDMGYNGNKTPRSQV
130 140 150 160 170 180
360 370 380 390 400 410
pF1KE3 FKPLELLWHSLDEWLVLTATELMKNKRDSTEITSILLKQKGQDQDAASIPPFEPPGPGSY
::::::::::::::::: ::::::::::::::::::::::::::::::::::::::::::
XP_016 FKPLELLWHSLDEWLVLIATELMKNKRDSTEITSILLKQKGQDQDAASIPPFEPPGPGSY
190 200 210 220 230 240
420 430 440 450 460 470
pF1KE3 ENLSTGTRESKPDALAGRQEASADCQDVISMTANRLSAVIQAFYMCCSCQMPPGMTSPRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ENLSTGTRESKPDALAGRQEASADCQDVISMTANRLSAVIQAFYMCCSCQMPPGMTSPRF
250 260 270 280 290 300
480 490 500 510 520 530
pF1KE3 IEFVCKHDEVLKCFVNRNPKIIFDHFHFLLECPELMSRFMHIIKAQPFKDRCEWFYEHLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IEFVCKHDEVLKCFVNRNPKIIFDHFHFLLECPELMSRFMHIIKAQPFKDRCEWFYEHLH
310 320 330 340 350 360
540 550 560 570 580 590
pF1KE3 SGQPDSDMVHRPVNENDILLVHRDSIFRSSCEVVSKANCAKLKQGIAVRFHGEEGMGQGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SGQPDSDMVHRPVNENDILLVHRDSIFRSSCEVVSKANCAKLKQGIAVRFHGEEGMGQGV
370 380 390 400 410 420
600 610 620 630 640 650
pF1KE3 VREWFDILSNEIVNPDYALFTQSADGTTFQPNSNSYVNPDHLNYFRFAGQILGLALNHRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VREWFDILSNEIVNPDYALFTQSADGTTFQPNSNSYVNPDHLNYFRFAGQILGLALNHRQ
430 440 450 460 470 480
660 670 680 690 700 710
pF1KE3 LVNIYFTRSFYKHILGIPVNYQDVASIDPEYAKNLQWILDNDISDLGLELTFSVETDVFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LVNIYFTRSFYKHILGIPVNYQDVASIDPEYAKNLQWILDNDISDLGLELTFSVETDVFG
490 500 510 520 530 540
720 730 740 750 760 770
pF1KE3 AMEEVPLKPGGGSILVTQNNKAEYVQLVTELRMTRAIQPQINAFLQGFHMFIPPSLIQLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AMEEVPLKPGGGSILVTQNNKAEYVQLVTELRMTRAIQPQINAFLQGFHMFIPPSLIQLF
550 560 570 580 590 600
780 790 800 810 820 830
pF1KE3 DEYELELLLSGMPEIDVSDWIKNTEYTSGYEREDPVIQWFWEVVEDITQEERVLLLQFVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DEYELELLLSGMPEIDVSDWIKNTEYTSGYEREDPVIQWFWEVVEDITQEERVLLLQFVT
610 620 630 640 650 660
840 850 860 870 880 890
pF1KE3 GSSRVPHGGFANIMGGSGLQNFTIAAVPYTPNLLPTSSTCINMLKLPEYPSKEILKDRLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSSRVPHGGFANIMGGSGLQNFTIAAVPYTPNLLPTSSTCINMLKLPEYPSKEILKDRLL
670 680 690 700 710 720
900
pF1KE3 VALHCGSYGYTMA
:::::::::::::
XP_016 VALHCGSYGYTMA
730 740
>>XP_016866608 (OMIM: 610876,616756) PREDICTED: E3 ubiqu (741 aa)
initn: 4749 init1: 4749 opt: 4749 Z-score: 3298.7 bits: 621.3 E(85289): 5.3e-177
Smith-Waterman score: 4749; 99.9% identity (99.9% similar) in 703 aa overlap (207-909:39-741)
180 190 200 210 220 230
pF1KE3 KTTVQCLLDSGADINRPNVSGATPLYFACSHGQRDTAQILLLRGAKYLPDKNGVTPLDLC
::::::::::::::::::::::::::::::
XP_016 TLCSMSVMLMLRMPWGRQHCMLPARTVTRRHGQRDTAQILLLRGAKYLPDKNGVTPLDLC
10 20 30 40 50 60
240 250 260 270 280 290
pF1KE3 VQGGYGETCEVLIQYHPRLFQTIIQMTQNEDLRENMLRQVLEHLSQQSESQYLKILTSLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VQGGYGETCEVLIQYHPRLFQTIIQMTQNEDLRENMLRQVLEHLSQQSESQYLKILTSLA
70 80 90 100 110 120
300 310 320 330 340 350
pF1KE3 EVATTNGHKLLSLSSNYDAQMKSLLRIVRMFCHVFRIGPSSPSNGIDMGYNGNKTPRSQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EVATTNGHKLLSLSSNYDAQMKSLLRIVRMFCHVFRIGPSSPSNGIDMGYNGNKTPRSQV
130 140 150 160 170 180
360 370 380 390 400 410
pF1KE3 FKPLELLWHSLDEWLVLTATELMKNKRDSTEITSILLKQKGQDQDAASIPPFEPPGPGSY
::::::::::::::::: ::::::::::::::::::::::::::::::::::::::::::
XP_016 FKPLELLWHSLDEWLVLIATELMKNKRDSTEITSILLKQKGQDQDAASIPPFEPPGPGSY
190 200 210 220 230 240
420 430 440 450 460 470
pF1KE3 ENLSTGTRESKPDALAGRQEASADCQDVISMTANRLSAVIQAFYMCCSCQMPPGMTSPRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ENLSTGTRESKPDALAGRQEASADCQDVISMTANRLSAVIQAFYMCCSCQMPPGMTSPRF
250 260 270 280 290 300
480 490 500 510 520 530
pF1KE3 IEFVCKHDEVLKCFVNRNPKIIFDHFHFLLECPELMSRFMHIIKAQPFKDRCEWFYEHLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IEFVCKHDEVLKCFVNRNPKIIFDHFHFLLECPELMSRFMHIIKAQPFKDRCEWFYEHLH
310 320 330 340 350 360
540 550 560 570 580 590
pF1KE3 SGQPDSDMVHRPVNENDILLVHRDSIFRSSCEVVSKANCAKLKQGIAVRFHGEEGMGQGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SGQPDSDMVHRPVNENDILLVHRDSIFRSSCEVVSKANCAKLKQGIAVRFHGEEGMGQGV
370 380 390 400 410 420
600 610 620 630 640 650
pF1KE3 VREWFDILSNEIVNPDYALFTQSADGTTFQPNSNSYVNPDHLNYFRFAGQILGLALNHRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VREWFDILSNEIVNPDYALFTQSADGTTFQPNSNSYVNPDHLNYFRFAGQILGLALNHRQ
430 440 450 460 470 480
660 670 680 690 700 710
pF1KE3 LVNIYFTRSFYKHILGIPVNYQDVASIDPEYAKNLQWILDNDISDLGLELTFSVETDVFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LVNIYFTRSFYKHILGIPVNYQDVASIDPEYAKNLQWILDNDISDLGLELTFSVETDVFG
490 500 510 520 530 540
720 730 740 750 760 770
pF1KE3 AMEEVPLKPGGGSILVTQNNKAEYVQLVTELRMTRAIQPQINAFLQGFHMFIPPSLIQLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AMEEVPLKPGGGSILVTQNNKAEYVQLVTELRMTRAIQPQINAFLQGFHMFIPPSLIQLF
550 560 570 580 590 600
780 790 800 810 820 830
pF1KE3 DEYELELLLSGMPEIDVSDWIKNTEYTSGYEREDPVIQWFWEVVEDITQEERVLLLQFVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DEYELELLLSGMPEIDVSDWIKNTEYTSGYEREDPVIQWFWEVVEDITQEERVLLLQFVT
610 620 630 640 650 660
840 850 860 870 880 890
pF1KE3 GSSRVPHGGFANIMGGSGLQNFTIAAVPYTPNLLPTSSTCINMLKLPEYPSKEILKDRLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSSRVPHGGFANIMGGSGLQNFTIAAVPYTPNLLPTSSTCINMLKLPEYPSKEILKDRLL
670 680 690 700 710 720
900
pF1KE3 VALHCGSYGYTMA
:::::::::::::
XP_016 VALHCGSYGYTMA
730 740
909 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 08:55:39 2016 done: Sun Nov 6 08:55:40 2016
Total Scan time: 11.560 Total Display time: 0.250
Function used was FASTA [36.3.4 Apr, 2011]