Result of FASTA (ccds) for
pFN21AE3917
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3917, 278 aa
1>>>pF1KE3917 278 - 278 aa - 278 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.4173+/-0.000672; mu= 14.3692+/- 0.040
mean_var=67.0744+/-13.561, 0's: 0 Z-trim(110.2): 39 B-trim: 129 in 1/53
Lambda= 0.156601
statistics sampled from 11426 (11457) to 11426 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.729), E-opt: 0.2 (0.352), width: 16
Scan time: 2.510
The best scores are: opt bits E(32554)
CCDS12526.1 FBXO17 gene_id:115290|Hs108|chr19 ( 278) 1960 451.3 3.6e-127
CCDS12527.1 FBXO27 gene_id:126433|Hs108|chr19 ( 283) 1157 269.8 1.5e-72
CCDS130.1 FBXO2 gene_id:26232|Hs108|chr1 ( 296) 501 121.6 6.4e-28
CCDS133.1 FBXO6 gene_id:26270|Hs108|chr1 ( 293) 492 119.6 2.6e-27
CCDS132.1 FBXO44 gene_id:93611|Hs108|chr1 ( 255) 450 110.1 1.7e-24
CCDS12529.1 NCCRP1 gene_id:342897|Hs108|chr19 ( 275) 254 65.8 3.8e-11
>>CCDS12526.1 FBXO17 gene_id:115290|Hs108|chr19 (278 aa)
initn: 1960 init1: 1960 opt: 1960 Z-score: 2396.6 bits: 451.3 E(32554): 3.6e-127
Smith-Waterman score: 1960; 100.0% identity (100.0% similar) in 278 aa overlap (1-278:1-278)
10 20 30 40 50 60
pF1KE3 MGARLSRRRLPADPSLALDALPPELLVQVLSHVPPRSLVTRCRPVCRAWRDIVDGPTVWL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 MGARLSRRRLPADPSLALDALPPELLVQVLSHVPPRSLVTRCRPVCRAWRDIVDGPTVWL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 LQLARDRSAEGRALYAVAQRCLPSNEDKEEFPLCALARYCLRAPFGRNLIFNSCGEQGFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 LQLARDRSAEGRALYAVAQRCLPSNEDKEEFPLCALARYCLRAPFGRNLIFNSCGEQGFR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 GWEVEHGGNGWAIEKNLTPVPGAPSQTCFVTSFEWCSKRQLVDLVMEGVWQELLDSAQIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 GWEVEHGGNGWAIEKNLTPVPGAPSQTCFVTSFEWCSKRQLVDLVMEGVWQELLDSAQIE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 ICVADWWGARENCGCVYQLRVRLLDVYEKEVVKFSASPDPVLQWTERGCRQVSHVFTNFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 ICVADWWGARENCGCVYQLRVRLLDVYEKEVVKFSASPDPVLQWTERGCRQVSHVFTNFG
190 200 210 220 230 240
250 260 270
pF1KE3 KGIRYVSFEQYGRDVSSWVGHYGALVTHSSVRVRIRLS
::::::::::::::::::::::::::::::::::::::
CCDS12 KGIRYVSFEQYGRDVSSWVGHYGALVTHSSVRVRIRLS
250 260 270
>>CCDS12527.1 FBXO27 gene_id:126433|Hs108|chr19 (283 aa)
initn: 899 init1: 856 opt: 1157 Z-score: 1416.0 bits: 269.8 E(32554): 1.5e-72
Smith-Waterman score: 1157; 57.7% identity (79.0% similar) in 286 aa overlap (1-278:1-283)
10 20 30 40 50
pF1KE3 MGARLSR---RRLPA---DPSLALD--ALPPELLVQVLSHVPPRSLVTRCRPVCRAWRDI
::: .:: :.:: .: ::: ::::::. ::::::::.:. ::: :::.:: .
CCDS12 MGASVSRGRAARVPAPEPEPEEALDLSQLPPELLLVVLSHVPPRTLLGRCRQVCRGWRAL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE3 VDGPTVWLLQLARDRSAEGRALYAVAQRCLPSNEDKEEFPLCALARYCLRAPFGRNLIFN
::: ..::: ::::..: :::: .:. : .. .. : : :.:.: : :.::::: :
CCDS12 VDGQALWLLILARDHGATGRALLHLARSC--QSPARNARP-CPLGRFCARRPIGRNLIRN
70 80 90 100 110
120 130 140 150 160 170
pF1KE3 SCGEQGFRGWEVEHGGNGWAIEKNLTPVPGAPSQTCFVTSFEWCSKRQLVDLVMEGVWQE
::..:.: : :.:::.::..:.: : :::::::::::::: :: :.:..:: ::.: :
CCDS12 PCGQEGLRKWMVQHGGDGWVVEENRTTVPGAPSQTCFVTSFSWCCKKQVLDLEEEGLWPE
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE3 LLDSAQIEICVADWWGARENCGCVYQLRVRLLDVYEKEVVKFSASPDPVLQWTERGCRQV
::::..:::::.::::::.. ::.:.: :.:::. . . :::: :::. ::.. .: .:
CCDS12 LLDSGRIEICVSDWWGARHDSGCMYRLLVQLLDANQTVLDKFSAVPDPIPQWNNNACLHV
180 190 200 210 220 230
240 250 260 270
pF1KE3 SHVFTNFGKGIRYVSFEQYGRDVSSWVGHYGALVTHSSVRVRIRLS
.:::.:. :.:.::::. :.:.. :.::::: ::.::: ::.:::
CCDS12 THVFSNIKMGVRFVSFEHRGQDTQFWAGHYGARVTNSSVIVRVRLS
240 250 260 270 280
>>CCDS130.1 FBXO2 gene_id:26232|Hs108|chr1 (296 aa)
initn: 662 init1: 242 opt: 501 Z-score: 614.7 bits: 121.6 E(32554): 6.4e-28
Smith-Waterman score: 614; 39.2% identity (63.4% similar) in 268 aa overlap (18-273:47-294)
10 20 30 40
pF1KE3 MGARLSRRRLPADPSLALDALPPELLVQVLSHVPPRSLVTRCRPVCR
:: :: ::..::. .: :: :: ::
CCDS13 SPEEQPEEASAEEERPEDQQEEEAAAAAAYLDELPEPLLLRVLAALPAAELVQACRLVCL
20 30 40 50 60 70
50 60 70 80 90 100
pF1KE3 AWRDIVDGPTVWLLQLARDRSAEGRALYAVAQRCLPSNEDK-EEFPLCALARYCLRAPFG
:...::: .:::. . :: : . . ..:. ..: . . :
CCDS13 RWKELVDGAPLWLLKCQQ----EG----LVPEGGVEEERDHWQQFYFLSKRR--------
80 90 100 110 120
110 120 130 140 150
pF1KE3 RNLIFNSCGEQGFRGW-EVEHGGNGWAIEKNLTPVPGAPS---------QTCFVTSFEWC
:::. : :::. ..:: .:::::.:: .:. .:: . . :..:::::
CCDS13 RNLLRNPCGEEDLEGWCDVEHGGDGWRVEE----LPGDSGVEFTHDESVKKYFASSFEWC
130 140 150 160 170
160 170 180 190 200 210
pF1KE3 SKRQLVDLVMEGVWQELLDSAQIEICVADWWGARENCGCVYQLRVRLLDVYEKEVVKFSA
: :..:: :: :.::::..: : : ::...: . ::.:.: :.::. .:. ...::.
CCDS13 RKAQVIDLQAEGYWEELLDTTQPAIVVKDWYSGRSDAGCLYELTVKLLSEHENVLAEFSS
180 190 200 210 220 230
220 230 240 250 260 270
pF1KE3 SPDPVLQWTERGC-RQVSHVFTNFGKGIRYVSFEQYGRDVSSWVGHYGALVTHSSVRVRI
. : : .. : ..::.::..: :.:.: ::. :.: : : .:: ::.::: :
CCDS13 GQVAVPQDSDGGGWMEISHTFTDYGPGVRFVRFEHGGQDSVYWKGWFGARVTNSSVWVEP
240 250 260 270 280 290
pF1KE3 RLS
>>CCDS133.1 FBXO6 gene_id:26270|Hs108|chr1 (293 aa)
initn: 571 init1: 409 opt: 492 Z-score: 603.8 bits: 119.6 E(32554): 2.6e-27
Smith-Waterman score: 601; 36.3% identity (64.0% similar) in 267 aa overlap (17-278:12-262)
10 20 30 40 50 60
pF1KE3 MGARLSRRRLPADPSLALDALPPELLVQVLSHVPPRSLVTRCRPVCRAWRDIVDGPTVWL
... :: ..:.....::: :.:. :: :: :::..: :.:
CCDS13 MDAPHSKAALDSINELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLMTLWK
10 20 30 40 50
70 80 90 100 110 120
pF1KE3 LQLARDRSAEGRALYAVAQRCLPSNEDKEEFPLCALARYCLRAPFGRNLIFNSCGEQGFR
. : :: . . . : : . : : ::. . :::. : :.:. .
CCDS13 RKCLR----EG---FITKDWDQPVA-DWKIF-------YFLRS-LHRNLLRNPCAEEDMF
60 70 80 90
130 140 150 160 170
pF1KE3 GWEVE-HGGNGWAIEK----NLTPVPGAPSQTCFVTSFEWCSKRQLVDLVMEGVWQELLD
.:... .::. : .:. . : : . ::::.: : : :::::: :: :.::::
CCDS13 AWQIDFNGGDRWKVESLPGAHGTDFPDPKVKKYFVTSYEMCLKSQLVDLVAEGYWEELLD
100 110 120 130 140 150
180 190 200 210 220 230
pF1KE3 SAQIEICVADWWGARENCGCVYQLRVRLLDVYEKEVVKFSASPDPVLQWTERGCRQVSHV
. . .: : ::..:: .:::.:::.:.: .. ...: : . ::.. .::..
CCDS13 TFRPDIVVKDWFAARADCGCTYQLKVQLASADYFVLASFEPPPVTIQQWNNATWTEVSYT
160 170 180 190 200 210
240 250 260 270
pF1KE3 FTNFGKGIRYVSFEQYGRDVSSWVGHYGALVTHSSVRVRIRLS
:... .:.::. :.. :::.. :.: :: ::.::. : ...
CCDS13 FSDYPRGVRYILFQHGGRDTQYWAGWYGPRVTNSSIVVSPKMTRNQASSEAQPGQKHGQE
220 230 240 250 260 270
CCDS13 EAAQSPYRAVVQIF
280 290
>>CCDS132.1 FBXO44 gene_id:93611|Hs108|chr1 (255 aa)
initn: 570 init1: 362 opt: 450 Z-score: 553.4 bits: 110.1 E(32554): 1.7e-24
Smith-Waterman score: 558; 36.3% identity (61.8% similar) in 262 aa overlap (18-273:6-250)
10 20 30 40 50 60
pF1KE3 MGARLSRRRLPADPSLALDALPPELLVQVLSHVPPRSLVTRCRPVCRAWRDIVDGPTVWL
.. :: ..:.....::: :.:. :: :: :::..: :.:
CCDS13 MAVGNINELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLVTLWK
10 20 30 40
70 80 90 100 110 120
pF1KE3 LQLARDRSAEGRALYAVAQRCLPSNEDKEEFPLCALARYCLRAPFGRNLIFNSCGEQGFR
. : :: . . . : : . : : ::. . :::. : :.:.::.
CCDS13 RKCLR----EG---FITEDWDQPVA-DWKIF-------YFLRS-LHRNLLHNPCAEEGFE
50 60 70 80 90
130 140 150 160 170
pF1KE3 GWEVE-HGGNGWAIEKNLT-----PVPGAPSQTCFVTSFEWCSKRQLVDLVMEGVWQELL
: .. .::. : .: .:. :. . ::::. : : :.::: :: :.::.
CCDS13 FWSLDVNGGDEWKVE-DLSRDQRKEFPNDQVKKYFVTSYYTCLKSQVVDLKAEGYWEELM
100 110 120 130 140 150
180 190 200 210 220 230
pF1KE3 DSAQIEICVADWWGARENCGCVYQLRVRLLDVYEKEVVKFSASPDPVLQWTERGCRQVSH
:... .: : ::..:: .:: ::: :.::. . . :. .: . : .. :.:::
CCDS13 DTTRPDIEVKDWFAARPDCGSKYQLCVQLLSSAHAPLGTFQPDPATIQQKSDAKWREVSH
160 170 180 190 200 210
240 250 260 270
pF1KE3 VFTNFGKGIRYVSFEQYGRDVSSWVGHYGALVTHSSVRVRIRLS
.:.:. :.::. :.. : :. :.: :: ::.::. .
CCDS13 TFSNYPPGVRYIWFQHGGVDTHYWAGWYGPRVTNSSITIGPPLP
220 230 240 250
>>CCDS12529.1 NCCRP1 gene_id:342897|Hs108|chr19 (275 aa)
initn: 309 init1: 163 opt: 254 Z-score: 313.6 bits: 65.8 E(32554): 3.8e-11
Smith-Waterman score: 256; 32.1% identity (54.2% similar) in 190 aa overlap (96-276:101-274)
70 80 90 100 110 120
pF1KE3 DRSAEGRALYAVAQRCLPSNEDKEEFPLCALARYCLRAPFGRNL-IFNSCGEQGFRGWEV
: : ::.: ... :.. : .
CCDS12 QLLLEEWGPLSGGLELPQRLTWKLLLLRRPLYRNLLRSPNPEGINIYEPAPPTGPTQRPL
80 90 100 110 120 130
130 140 150 160 170 180
pF1KE3 EHGGN--GWAIEKNLTPVPGAPSQTCFVTSFEWCSKRQLVDLVMEGVWQELLDSAQIEIC
: :: :: :. . .:. : :.: :::. ::.:.::::. : :
CCDS12 ETLGNFRGWYIRTEKLQ----QNQS-------WTVKQQCVDLLAEGLWEELLDDEQPAIT
140 150 160 170
190 200 210 220 230
pF1KE3 VADWWGARENCGCVYQLRVRLLDVYEKEVV-KFSASP-----DPVLQWTERGCRQVSHVF
: ::. . .:::.:.: :: . .. :. . ..: : .:. ::::::
CCDS12 VMDWFEDSRLDACVYELHVWLLAADRRTVIAQHHVAPRTSGRGPPGRWV-----QVSHVF
180 190 200 210 220 230
240 250 260 270
pF1KE3 TNFGKGIRYVSFEQYGRDVSSWVGHYGALVTHSSVRVRIRLS
..: :.:.. : . ... : . :: ::: :..:
CCDS12 RHYGPGVRFIHFLHKAKNRMEPGGLRRTRVTDSSVSVQLRE
240 250 260 270
278 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 08:58:49 2016 done: Sun Nov 6 08:58:49 2016
Total Scan time: 2.510 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]