Result of FASTA (ccds) for
pFN21AE3896
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3896, 325 aa
1>>>pF1KE3896 325 - 325 aa - 325 aa
Library: human.CCDS.faa
18921897 residues in 33420 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.8355+/-0.000984; mu= 14.2338+/- 0.059
mean_var=89.1940+/-17.586, 0's: 0 Z-trim(106.7): 42 B-trim: 183 in 1/51
Lambda= 0.135802
statistics sampled from 9251 (9285) to 9251 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.646), E-opt: 0.2 (0.278), width: 16
Scan time: 1.320
The best scores are: opt bits E(33420)
CCDS13468.1 STX16 gene_id:8675|Hs109|chr20 ( 325) 2071 415.7 2.5e-116
CCDS46619.1 STX16 gene_id:8675|Hs109|chr20 ( 321) 2028 407.3 8.6e-114
CCDS46620.1 STX16 gene_id:8675|Hs109|chr20 ( 308) 1809 364.4 6.9e-101
CCDS13469.1 STX16 gene_id:8675|Hs109|chr20 ( 304) 1792 361.0 6.8e-100
CCDS56199.1 STX16 gene_id:8675|Hs109|chr20 ( 272) 1747 352.2 2.8e-97
CCDS310.1 STX12 gene_id:23673|Hs109|chr1 ( 276) 329 74.4 1.2e-13
CCDS5153.1 STX7 gene_id:8417|Hs109|chr6 ( 261) 318 72.2 5.2e-13
CCDS34655.1 STX1A gene_id:6804|Hs109|chr7 ( 288) 290 66.7 2.5e-11
>>CCDS13468.1 STX16 gene_id:8675|Hs109|chr20 (325 aa)
initn: 2071 init1: 2071 opt: 2071 Z-score: 2202.0 bits: 415.7 E(33420): 2.5e-116
Smith-Waterman score: 2071; 100.0% identity (100.0% similar) in 325 aa overlap (1-325:1-325)
10 20 30 40 50 60
pF1KE3 MATRRLTDAFLLLRNNSIQNRQLLAEQVSSHITSSPLHSRSIAAELDELADDRMALVSGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 MATRRLTDAFLLLRNNSIQNRQLLAEQVSSHITSSPLHSRSIAAELDELADDRMALVSGI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 SLDPEAAIGVTKRPPPKWVDGVDEIQYDVGRIKQKMKELASLHDKHLNRPTLDDSSEEEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 SLDPEAAIGVTKRPPPKWVDGVDEIQYDVGRIKQKMKELASLHDKHLNRPTLDDSSEEEH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 AIEITTQEITQLFHRCQRAVQALPSRARACSEQEGRLLGNVVASLAQALQELSTSFRHAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 AIEITTQEITQLFHRCQRAVQALPSRARACSEQEGRLLGNVVASLAQALQELSTSFRHAQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 SGYLKRMKNREERSQHFFDTSVPLMDDGDDNTLYHRGFTEDQLVLVEQNTLMVEEREREI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 SGYLKRMKNREERSQHFFDTSVPLMDDGDDNTLYHRGFTEDQLVLVEQNTLMVEEREREI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 RQIVQSISDLNEIFRDLGAMIVEQGTVLDRIDYNVEQSCIKTEDGLKQLHKAEQYQKKNR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 RQIVQSISDLNEIFRDLGAMIVEQGTVLDRIDYNVEQSCIKTEDGLKQLHKAEQYQKKNR
250 260 270 280 290 300
310 320
pF1KE3 KMLVILILFVIIIVLIVVLVGVKSR
:::::::::::::::::::::::::
CCDS13 KMLVILILFVIIIVLIVVLVGVKSR
310 320
>>CCDS46619.1 STX16 gene_id:8675|Hs109|chr20 (321 aa)
initn: 1780 init1: 1780 opt: 2028 Z-score: 2156.6 bits: 407.3 E(33420): 8.6e-114
Smith-Waterman score: 2028; 98.8% identity (98.8% similar) in 325 aa overlap (1-325:1-321)
10 20 30 40 50 60
pF1KE3 MATRRLTDAFLLLRNNSIQNRQLLAEQVSSHITSSPLHSRSIAAELDELADDRMALVSGI
:::::::::::::::::::::::::::::::::::::::::::: ::::::::::::
CCDS46 MATRRLTDAFLLLRNNSIQNRQLLAEQVSSHITSSPLHSRSIAA----LADDRMALVSGI
10 20 30 40 50
70 80 90 100 110 120
pF1KE3 SLDPEAAIGVTKRPPPKWVDGVDEIQYDVGRIKQKMKELASLHDKHLNRPTLDDSSEEEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 SLDPEAAIGVTKRPPPKWVDGVDEIQYDVGRIKQKMKELASLHDKHLNRPTLDDSSEEEH
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE3 AIEITTQEITQLFHRCQRAVQALPSRARACSEQEGRLLGNVVASLAQALQELSTSFRHAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 AIEITTQEITQLFHRCQRAVQALPSRARACSEQEGRLLGNVVASLAQALQELSTSFRHAQ
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE3 SGYLKRMKNREERSQHFFDTSVPLMDDGDDNTLYHRGFTEDQLVLVEQNTLMVEEREREI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 SGYLKRMKNREERSQHFFDTSVPLMDDGDDNTLYHRGFTEDQLVLVEQNTLMVEEREREI
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE3 RQIVQSISDLNEIFRDLGAMIVEQGTVLDRIDYNVEQSCIKTEDGLKQLHKAEQYQKKNR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 RQIVQSISDLNEIFRDLGAMIVEQGTVLDRIDYNVEQSCIKTEDGLKQLHKAEQYQKKNR
240 250 260 270 280 290
310 320
pF1KE3 KMLVILILFVIIIVLIVVLVGVKSR
:::::::::::::::::::::::::
CCDS46 KMLVILILFVIIIVLIVVLVGVKSR
300 310 320
>>CCDS46620.1 STX16 gene_id:8675|Hs109|chr20 (308 aa)
initn: 1955 init1: 1805 opt: 1809 Z-score: 1925.0 bits: 364.4 E(33420): 6.9e-101
Smith-Waterman score: 1925; 94.8% identity (94.8% similar) in 325 aa overlap (1-325:1-308)
10 20 30 40 50 60
pF1KE3 MATRRLTDAFLLLRNNSIQNRQLLAEQVSSHITSSPLHSRSIAAELDELADDRMALVSGI
::::::::::::::::::::::::::: ::::::::::::::::
CCDS46 MATRRLTDAFLLLRNNSIQNRQLLAEQ-----------------ELDELADDRMALVSGI
10 20 30 40
70 80 90 100 110 120
pF1KE3 SLDPEAAIGVTKRPPPKWVDGVDEIQYDVGRIKQKMKELASLHDKHLNRPTLDDSSEEEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 SLDPEAAIGVTKRPPPKWVDGVDEIQYDVGRIKQKMKELASLHDKHLNRPTLDDSSEEEH
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE3 AIEITTQEITQLFHRCQRAVQALPSRARACSEQEGRLLGNVVASLAQALQELSTSFRHAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 AIEITTQEITQLFHRCQRAVQALPSRARACSEQEGRLLGNVVASLAQALQELSTSFRHAQ
110 120 130 140 150 160
190 200 210 220 230 240
pF1KE3 SGYLKRMKNREERSQHFFDTSVPLMDDGDDNTLYHRGFTEDQLVLVEQNTLMVEEREREI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 SGYLKRMKNREERSQHFFDTSVPLMDDGDDNTLYHRGFTEDQLVLVEQNTLMVEEREREI
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE3 RQIVQSISDLNEIFRDLGAMIVEQGTVLDRIDYNVEQSCIKTEDGLKQLHKAEQYQKKNR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 RQIVQSISDLNEIFRDLGAMIVEQGTVLDRIDYNVEQSCIKTEDGLKQLHKAEQYQKKNR
230 240 250 260 270 280
310 320
pF1KE3 KMLVILILFVIIIVLIVVLVGVKSR
:::::::::::::::::::::::::
CCDS46 KMLVILILFVIIIVLIVVLVGVKSR
290 300
>>CCDS13469.1 STX16 gene_id:8675|Hs109|chr20 (304 aa)
initn: 1784 init1: 1784 opt: 1792 Z-score: 1907.0 bits: 361.0 E(33420): 6.8e-100
Smith-Waterman score: 1892; 93.5% identity (93.5% similar) in 325 aa overlap (1-325:1-304)
10 20 30 40 50 60
pF1KE3 MATRRLTDAFLLLRNNSIQNRQLLAEQVSSHITSSPLHSRSIAAELDELADDRMALVSGI
::::::::::::::::::::::::::: ::::::::::::
CCDS13 MATRRLTDAFLLLRNNSIQNRQLLAEQ---------------------LADDRMALVSGI
10 20 30
70 80 90 100 110 120
pF1KE3 SLDPEAAIGVTKRPPPKWVDGVDEIQYDVGRIKQKMKELASLHDKHLNRPTLDDSSEEEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 SLDPEAAIGVTKRPPPKWVDGVDEIQYDVGRIKQKMKELASLHDKHLNRPTLDDSSEEEH
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE3 AIEITTQEITQLFHRCQRAVQALPSRARACSEQEGRLLGNVVASLAQALQELSTSFRHAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 AIEITTQEITQLFHRCQRAVQALPSRARACSEQEGRLLGNVVASLAQALQELSTSFRHAQ
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE3 SGYLKRMKNREERSQHFFDTSVPLMDDGDDNTLYHRGFTEDQLVLVEQNTLMVEEREREI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 SGYLKRMKNREERSQHFFDTSVPLMDDGDDNTLYHRGFTEDQLVLVEQNTLMVEEREREI
160 170 180 190 200 210
250 260 270 280 290 300
pF1KE3 RQIVQSISDLNEIFRDLGAMIVEQGTVLDRIDYNVEQSCIKTEDGLKQLHKAEQYQKKNR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 RQIVQSISDLNEIFRDLGAMIVEQGTVLDRIDYNVEQSCIKTEDGLKQLHKAEQYQKKNR
220 230 240 250 260 270
310 320
pF1KE3 KMLVILILFVIIIVLIVVLVGVKSR
:::::::::::::::::::::::::
CCDS13 KMLVILILFVIIIVLIVVLVGVKSR
280 290 300
>>CCDS56199.1 STX16 gene_id:8675|Hs109|chr20 (272 aa)
initn: 1747 init1: 1747 opt: 1747 Z-score: 1860.1 bits: 352.2 E(33420): 2.8e-97
Smith-Waterman score: 1747; 100.0% identity (100.0% similar) in 272 aa overlap (54-325:1-272)
30 40 50 60 70 80
pF1KE3 LAEQVSSHITSSPLHSRSIAAELDELADDRMALVSGISLDPEAAIGVTKRPPPKWVDGVD
::::::::::::::::::::::::::::::
CCDS56 MALVSGISLDPEAAIGVTKRPPPKWVDGVD
10 20 30
90 100 110 120 130 140
pF1KE3 EIQYDVGRIKQKMKELASLHDKHLNRPTLDDSSEEEHAIEITTQEITQLFHRCQRAVQAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 EIQYDVGRIKQKMKELASLHDKHLNRPTLDDSSEEEHAIEITTQEITQLFHRCQRAVQAL
40 50 60 70 80 90
150 160 170 180 190 200
pF1KE3 PSRARACSEQEGRLLGNVVASLAQALQELSTSFRHAQSGYLKRMKNREERSQHFFDTSVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 PSRARACSEQEGRLLGNVVASLAQALQELSTSFRHAQSGYLKRMKNREERSQHFFDTSVP
100 110 120 130 140 150
210 220 230 240 250 260
pF1KE3 LMDDGDDNTLYHRGFTEDQLVLVEQNTLMVEEREREIRQIVQSISDLNEIFRDLGAMIVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 LMDDGDDNTLYHRGFTEDQLVLVEQNTLMVEEREREIRQIVQSISDLNEIFRDLGAMIVE
160 170 180 190 200 210
270 280 290 300 310 320
pF1KE3 QGTVLDRIDYNVEQSCIKTEDGLKQLHKAEQYQKKNRKMLVILILFVIIIVLIVVLVGVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 QGTVLDRIDYNVEQSCIKTEDGLKQLHKAEQYQKKNRKMLVILILFVIIIVLIVVLVGVK
220 230 240 250 260 270
pF1KE3 SR
::
CCDS56 SR
>>CCDS310.1 STX12 gene_id:23673|Hs109|chr1 (276 aa)
initn: 316 init1: 292 opt: 329 Z-score: 358.5 bits: 74.4 E(33420): 1.2e-13
Smith-Waterman score: 329; 29.3% identity (62.5% similar) in 256 aa overlap (76-320:17-268)
50 60 70 80 90 100
pF1KE3 LDELADDRMALVSGISLDPEAAIGVTKRPPPKWVDGVDEIQYDVGRIKQKMKELASLHDK
:. : . :: : :.. . :....
CCDS31 MSYGPLDMYRNPGPSGPQLRDFSSIIQTCSGNIQRISQATAQIKNL
10 20 30 40
110 120 130 140 150
pF1KE3 HLNRPTLDDSS---EEEHAIEITTQEITQLFHRCQRAVQALP-----SRARACSEQEGRL
. : .::: :. . .. .:..... .. . . .:: :. : :. ::
CCDS31 MSQLGTKQDSSKLQENLQQLQHSTNQLAKETNELLKELGSLPLPLSTSEQRQQRLQKERL
50 60 70 80 90 100
160 170 180 190 200 210
pF1KE3 LGNVVASLA--QALQELSTSFRHAQSGYLKRMKNREERSQHFFDTSVPLMDDGDD-NTLY
... :.: ::.:. .: .. .: : .: .. . .. .:. .. : .
CCDS31 MNDFSAALNNFQAVQR-RVSEKEKESIARARAGSRLSAEERQREEQLVSFDSHEEWNQMQ
110 120 130 140 150 160
220 230 240 250 260 270
pF1KE3 HRGFTEDQLVLVEQNTLMVEEREREIRQIVQSISDLNEIFRDLGAMIVEQGTVLDRIDYN
. ::.....::. ...::: :::. .: :.:.::.::. :: .:: ..: :. :
CCDS31 SQ---EDEVAITEQDLELIKERETAIRQLEADILDVNQIFKDLAMMIHDQGDLIDSIEAN
170 180 190 200 210 220
280 290 300 310 320
pF1KE3 VEQSCIKTEDGLKQLHKAEQYQKKNRKMLVILILFVIIIVLIVVLVGVKSR
::.: ...: . .::..: ::::.:: . ::.: . .:.::. :.
CCDS31 VESSEVHVERATEQLQRAAYYQKKSRKKMCILVLVLSVIILILGLIIWLVYKTK
230 240 250 260 270
>>CCDS5153.1 STX7 gene_id:8417|Hs109|chr6 (261 aa)
initn: 342 init1: 264 opt: 318 Z-score: 347.2 bits: 72.2 E(33420): 5.2e-13
Smith-Waterman score: 318; 30.8% identity (63.3% similar) in 237 aa overlap (94-320:23-255)
70 80 90 100 110 120
pF1KE3 PEAAIGVTKRPPPKWVDGVDEIQYDVGRIKQKMKELASLHDKHLNR-PTLDDSSEEEHAI
::. . . .. ::. : .:: : .. .
CCDS51 MSYTPGVGGDPAQLAQRISSNIQKITQCSVEIQRTLNQLGTPQDSPELRQQL
10 20 30 40 50
130 140 150 160 170 180
pF1KE3 EITTQEITQLFHRCQRAVQALPSRARACSEQEGRLLGN--VVASLAQALQELSTSFRHAQ
. : .:: .. .. .. . : . :::. : . . .:: .. .: :.:...:
CCDS51 QQKQQYTNQLAKETDKYIKEFGSLPTTPSEQRQRKIQKDRLVAEFTTSL----TNFQKVQ
60 70 80 90 100
190 200 210 220 230
pF1KE3 SGYLKRMKN--REERSQHFFDTSVPLMDDGDDNTLYHRGFTEDQLV-----LVEQNTLMV
.: :. . :.. . : : .. . : . .. :. :. ..:.. ..
CCDS51 RQAAEREKEFVARVRASSRVSGSFPEDSSKERNLVSWESQTQPQVQVQDEEITEDDLRLI
110 120 130 140 150 160
240 250 260 270 280 290
pF1KE3 EEREREIRQIVQSISDLNEIFRDLGAMIVEQGTVLDRIDYNVEQSCIKTEDGLKQLHKAE
.::: :::. .: :.::::.::: :: ::: :.: :. :::.. ...... .:: .:
CCDS51 HERESSIRQLEADIMDINEIFKDLGMMIHEQGDVIDSIEANVENAEVHVQQANQQLSRAA
170 180 190 200 210 220
300 310 320
pF1KE3 QYQKKNRKMLVILILFVIIIVLIVVLVGVKSR
.::.:.:: : :.::...: : :. :.
CCDS51 DYQRKSRKTLCIIILILVIGVAIISLIIWGLNH
230 240 250 260
>>CCDS34655.1 STX1A gene_id:6804|Hs109|chr7 (288 aa)
initn: 175 init1: 152 opt: 290 Z-score: 317.0 bits: 66.7 E(33420): 2.5e-11
Smith-Waterman score: 290; 25.1% identity (61.6% similar) in 271 aa overlap (63-321:17-284)
40 50 60 70 80 90
pF1KE3 TSSPLHSRSIAAELDELADDRMALVSGISLDPEAAIGVTK-RPPPKWVDGVDEIQYDVGR
: ..:. : . : .. . :.::. . .
CCDS34 MKDRTQELRTAKDSDDDDDVAVTVDRDRFMDEFFEQVEEIRGFIDK
10 20 30 40
100 110 120 130 140
pF1KE3 IKQKMKELASLHDKHLNRPTLDDSSEEE-----HAIEITTQEITQLFHRCQRAVQALPSR
: ....:. :. : :. :....:: :. :.... . .. ..... .
CCDS34 IAENVEEVKRKHSAILASPNPDEKTKEELEELMSDIKKTANKVRSKLKSIEQSIEQEEGL
50 60 70 80 90 100
150 160 170 180 190 200
pF1KE3 ARACSEQEGRLLGNVVASLAQALQELSTSFRHAQSGYLKRMKNREERSQHFFD---TSVP
:. .. . : . ..:.. . :. . . .:: : .: :.: .:. .. ::
CCDS34 NRSSADLRIRKTQH--STLSRKFVEVMSEYNATQSDYRERCKGRIQRQLEITGRTTTSEE
110 120 130 140 150 160
210 220 230 240 250 260
pF1KE3 LMD--DGDDNTLYHRGFTEDQLVLVEQNTLMVEEREREIRQIVQSISDLNEIFRDLGAMI
: : .. . ... :. :. . .: .: :. :: .. .:: .:...: :.. ..
CCDS34 LEDMLESGNPAIFASGIIMDSSI-SKQALSEIETRHSEIIKLENSIRELHDMFMDMAMLV
170 180 190 200 210 220
270 280 290 300 310 320
pF1KE3 VEQGTVLDRIDYNVEQSCIKTEDGLKQLHKAEQYQKKNR-KMLVILILFVIIIVLIVVLV
:: ..:::.::::.. .: .... .:: .::.: : : ..:.: ::. ..:. :
CCDS34 ESQGEMIDRIEYNVEHAVDYVERAVSDTKKAVKYQSKARRKKIMIIICCVILGIVIASTV
230 240 250 260 270 280
pF1KE3 GVKSR
:
CCDS34 GGIFA
325 residues in 1 query sequences
18921897 residues in 33420 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Wed Aug 4 20:31:56 2021 done: Wed Aug 4 20:31:56 2021
Total Scan time: 1.320 Total Display time: 0.060
Function used was FASTA [36.3.4 Apr, 2011]