Result of FASTA (omim) for
pFN21AE3763
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3763, 559 aa
1>>>pF1KE3763 559 - 559 aa - 559 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.3137+/-0.000585; mu= 10.5864+/- 0.035
mean_var=481.1548+/-114.562, 0's: 0 Z-trim(114.5): 2146 B-trim: 1588 in 2/56
Lambda= 0.058470
statistics sampled from 21645 (24463) to 21645 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.643), E-opt: 0.2 (0.287), width: 16
Scan time: 10.590
The best scores are: opt bits E(85289)
NP_006242 (OMIM: 602739) 5'-AMP-activated protein ( 559) 3762 333.4 1.1e-90
XP_016865114 (OMIM: 602739) PREDICTED: 5'-AMP-acti ( 533) 3481 309.7 1.5e-83
NP_996790 (OMIM: 602739) 5'-AMP-activated protein ( 574) 3002 269.3 2.3e-71
XP_016865113 (OMIM: 602739) PREDICTED: 5'-AMP-acti ( 548) 2980 267.5 8.1e-71
NP_006243 (OMIM: 600497) 5'-AMP-activated protein ( 552) 2829 254.7 5.5e-67
XP_016857182 (OMIM: 600497) PREDICTED: 5'-AMP-acti ( 462) 2274 207.8 6.3e-53
XP_016857183 (OMIM: 600497) PREDICTED: 5'-AMP-acti ( 462) 2274 207.8 6.3e-53
XP_016857181 (OMIM: 600497) PREDICTED: 5'-AMP-acti ( 462) 2274 207.8 6.3e-53
XP_006714545 (OMIM: 602739) PREDICTED: 5'-AMP-acti ( 301) 2022 186.1 1.3e-46
NP_056006 (OMIM: 608973) serine/threonine-protein ( 926) 976 98.8 7.8e-20
NP_775490 (OMIM: 605705,616341) serine/threonine-p ( 783) 956 97.0 2.3e-19
NP_003948 (OMIM: 609236) serine/threonine-protein ( 668) 933 94.9 8.4e-19
NP_001243558 (OMIM: 609236) serine/threonine-prote ( 674) 933 94.9 8.4e-19
XP_005253275 (OMIM: 609236) PREDICTED: serine/thre ( 720) 933 95.0 8.6e-19
NP_001243556 (OMIM: 609236) serine/threonine-prote ( 736) 933 95.0 8.7e-19
XP_006718437 (OMIM: 609236) PREDICTED: serine/thre ( 758) 933 95.0 8.8e-19
XP_016874025 (OMIM: 609236) PREDICTED: serine/thre ( 858) 933 95.1 9.3e-19
XP_016874022 (OMIM: 609236) PREDICTED: serine/thre ( 880) 933 95.2 9.4e-19
XP_011527776 (OMIM: 605705,616341) PREDICTED: seri ( 734) 930 94.8 1e-18
NP_001156769 (OMIM: 600526) serine/threonine-prote ( 709) 915 93.5 2.5e-18
NP_001156768 (OMIM: 600526) serine/threonine-prote ( 719) 915 93.5 2.5e-18
NP_004945 (OMIM: 600526) serine/threonine-protein ( 724) 915 93.5 2.5e-18
XP_011543100 (OMIM: 600526) PREDICTED: serine/thre ( 729) 915 93.5 2.5e-18
XP_016872800 (OMIM: 600526) PREDICTED: serine/thre ( 738) 915 93.5 2.5e-18
XP_011543099 (OMIM: 600526) PREDICTED: serine/thre ( 739) 915 93.5 2.5e-18
XP_011543098 (OMIM: 600526) PREDICTED: serine/thre ( 744) 915 93.5 2.5e-18
XP_011543097 (OMIM: 600526) PREDICTED: serine/thre ( 745) 915 93.5 2.5e-18
XP_011543096 (OMIM: 600526) PREDICTED: serine/thre ( 753) 915 93.5 2.5e-18
NP_115806 (OMIM: 609235) serine/threonine-protein ( 778) 915 93.5 2.6e-18
NP_059672 (OMIM: 600526) serine/threonine-protein ( 745) 911 93.2 3.2e-18
XP_016872799 (OMIM: 600526) PREDICTED: serine/thre ( 763) 911 93.2 3.2e-18
XP_011543093 (OMIM: 600526) PREDICTED: serine/thre ( 798) 911 93.2 3.3e-18
XP_011543095 (OMIM: 600526) PREDICTED: serine/thre ( 784) 901 92.4 5.8e-18
NP_001034558 (OMIM: 600526) serine/threonine-prote ( 788) 901 92.4 5.8e-18
XP_011543094 (OMIM: 600526) PREDICTED: serine/thre ( 793) 901 92.4 5.9e-18
XP_011543092 (OMIM: 600526) PREDICTED: serine/thre ( 799) 901 92.4 5.9e-18
XP_011543091 (OMIM: 600526) PREDICTED: serine/thre ( 808) 901 92.4 5.9e-18
XP_016872913 (OMIM: 614776) PREDICTED: serine/thre (1213) 902 92.8 6.6e-18
NP_001268678 (OMIM: 614776) serine/threonine-prote (1261) 902 92.9 6.7e-18
XP_005271539 (OMIM: 614776) PREDICTED: serine/thre (1321) 902 92.9 6.9e-18
NP_001243559 (OMIM: 609236) serine/threonine-prote ( 766) 898 92.1 6.9e-18
XP_005273191 (OMIM: 606511) PREDICTED: serine/thre ( 781) 895 91.9 8.3e-18
XP_011507863 (OMIM: 606511) PREDICTED: serine/thre ( 788) 895 91.9 8.3e-18
NP_001273053 (OMIM: 606511) serine/threonine-prote ( 796) 895 91.9 8.3e-18
XP_005267700 (OMIM: 602678) PREDICTED: MAP/microtu ( 643) 893 91.5 8.5e-18
NP_002367 (OMIM: 602678) MAP/microtubule affinity- ( 729) 893 91.6 9e-18
XP_005267698 (OMIM: 602678) PREDICTED: MAP/microtu ( 738) 893 91.6 9.1e-18
XP_006720209 (OMIM: 602678) PREDICTED: MAP/microtu ( 739) 893 91.7 9.1e-18
NP_001122391 (OMIM: 602678) MAP/microtubule affini ( 744) 893 91.7 9.1e-18
NP_001122390 (OMIM: 602678) MAP/microtubule affini ( 753) 893 91.7 9.1e-18
>>NP_006242 (OMIM: 602739) 5'-AMP-activated protein kina (559 aa)
initn: 3762 init1: 3762 opt: 3762 Z-score: 1748.9 bits: 333.4 E(85289): 1.1e-90
Smith-Waterman score: 3762; 100.0% identity (100.0% similar) in 559 aa overlap (1-559:1-559)
10 20 30 40 50 60
pF1KE3 MRRLSSWRKMATAEKQKHDGRVKIGHYILGDTLGVGTFGKVKVGKHELTGHKVAVKILNR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MRRLSSWRKMATAEKQKHDGRVKIGHYILGDTLGVGTFGKVKVGKHELTGHKVAVKILNR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 QKIRSLDVVGKIRREIQNLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 QKIRSLDVVGKIRREIQNLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 RLDEKESRRLFQQILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 RLDEKESRRLFQQILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 LRTSCGSPNYAAPEVISGRLYAGPEVDIWSSGVILYALLCGTLPFDDDHVPTLFKKICDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 LRTSCGSPNYAAPEVISGRLYAGPEVDIWSSGVILYALLCGTLPFDDDHVPTLFKKICDG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 IFYTPQYLNPSVISLLKHMLQVDPMKRATIKDIREHEWFKQDLPKYLFPEDPSYSSTMID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 IFYTPQYLNPSVISLLKHMLQVDPMKRATIKDIREHEWFKQDLPKYLFPEDPSYSSTMID
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 DEALKEVCEKFECSEEEVLSCLYNRNHQDPLAVAYHLIIDNRRIMNEAKDFYLATSPPDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 DEALKEVCEKFECSEEEVLSCLYNRNHQDPLAVAYHLIIDNRRIMNEAKDFYLATSPPDS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 FLDDHHLTRPHPERVPFLVAETPRARHTLDELNPQKSKHQGVRKAKWHLGIRSQSRPNDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 FLDDHHLTRPHPERVPFLVAETPRARHTLDELNPQKSKHQGVRKAKWHLGIRSQSRPNDI
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 MAEVCRAIKQLDYEWKVVNPYYLRVRRKNPVTSTYSKMSLQLYQVDSRTYLLDFRSIDDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MAEVCRAIKQLDYEWKVVNPYYLRVRRKNPVTSTYSKMSLQLYQVDSRTYLLDFRSIDDE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 ITEAKSGTATPQRSGSVSNYRSCQRSDSDAEAQGKSSEVSLTSSVTSLDSSPVDLTPRPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 ITEAKSGTATPQRSGSVSNYRSCQRSDSDAEAQGKSSEVSLTSSVTSLDSSPVDLTPRPG
490 500 510 520 530 540
550
pF1KE3 SHTIEFFEMCANLIKILAQ
:::::::::::::::::::
NP_006 SHTIEFFEMCANLIKILAQ
550
>>XP_016865114 (OMIM: 602739) PREDICTED: 5'-AMP-activate (533 aa)
initn: 3481 init1: 3481 opt: 3481 Z-score: 1620.9 bits: 309.7 E(85289): 1.5e-83
Smith-Waterman score: 3481; 100.0% identity (100.0% similar) in 517 aa overlap (43-559:17-533)
20 30 40 50 60 70
pF1KE3 AEKQKHDGRVKIGHYILGDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKI
::::::::::::::::::::::::::::::
XP_016 MQVKNIRKLPCQIIQSVGKHELTGHKVAVKILNRQKIRSLDVVGKI
10 20 30 40
80 90 100 110 120 130
pF1KE3 RREIQNLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RREIQNLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQ
50 60 70 80 90 100
140 150 160 170 180 190
pF1KE3 QILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYAA
110 120 130 140 150 160
200 210 220 230 240 250
pF1KE3 PEVISGRLYAGPEVDIWSSGVILYALLCGTLPFDDDHVPTLFKKICDGIFYTPQYLNPSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PEVISGRLYAGPEVDIWSSGVILYALLCGTLPFDDDHVPTLFKKICDGIFYTPQYLNPSV
170 180 190 200 210 220
260 270 280 290 300 310
pF1KE3 ISLLKHMLQVDPMKRATIKDIREHEWFKQDLPKYLFPEDPSYSSTMIDDEALKEVCEKFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ISLLKHMLQVDPMKRATIKDIREHEWFKQDLPKYLFPEDPSYSSTMIDDEALKEVCEKFE
230 240 250 260 270 280
320 330 340 350 360 370
pF1KE3 CSEEEVLSCLYNRNHQDPLAVAYHLIIDNRRIMNEAKDFYLATSPPDSFLDDHHLTRPHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CSEEEVLSCLYNRNHQDPLAVAYHLIIDNRRIMNEAKDFYLATSPPDSFLDDHHLTRPHP
290 300 310 320 330 340
380 390 400 410 420 430
pF1KE3 ERVPFLVAETPRARHTLDELNPQKSKHQGVRKAKWHLGIRSQSRPNDIMAEVCRAIKQLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ERVPFLVAETPRARHTLDELNPQKSKHQGVRKAKWHLGIRSQSRPNDIMAEVCRAIKQLD
350 360 370 380 390 400
440 450 460 470 480 490
pF1KE3 YEWKVVNPYYLRVRRKNPVTSTYSKMSLQLYQVDSRTYLLDFRSIDDEITEAKSGTATPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YEWKVVNPYYLRVRRKNPVTSTYSKMSLQLYQVDSRTYLLDFRSIDDEITEAKSGTATPQ
410 420 430 440 450 460
500 510 520 530 540 550
pF1KE3 RSGSVSNYRSCQRSDSDAEAQGKSSEVSLTSSVTSLDSSPVDLTPRPGSHTIEFFEMCAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RSGSVSNYRSCQRSDSDAEAQGKSSEVSLTSSVTSLDSSPVDLTPRPGSHTIEFFEMCAN
470 480 490 500 510 520
pF1KE3 LIKILAQ
:::::::
XP_016 LIKILAQ
530
>>NP_996790 (OMIM: 602739) 5'-AMP-activated protein kina (574 aa)
initn: 3748 init1: 2963 opt: 3002 Z-score: 1402.3 bits: 269.3 E(85289): 2.3e-71
Smith-Waterman score: 3722; 97.4% identity (97.4% similar) in 574 aa overlap (1-559:1-574)
10 20 30 40 50 60
pF1KE3 MRRLSSWRKMATAEKQKHDGRVKIGHYILGDTLGVGTFGKVKVGKHELTGHKVAVKILNR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_996 MRRLSSWRKMATAEKQKHDGRVKIGHYILGDTLGVGTFGKVKVGKHELTGHKVAVKILNR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 QKIRSLDVVGKIRREIQNLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_996 QKIRSLDVVGKIRREIQNLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNG
70 80 90 100 110 120
130 140 150 160
pF1KE3 R---------------LDEKESRRLFQQILSGVDYCHRHMVVHRDLKPENVLLDAHMNAK
: ::::::::::::::::::::::::::::::::::::::::::::
NP_996 RKSDVPGVVKTGSTKELDEKESRRLFQQILSGVDYCHRHMVVHRDLKPENVLLDAHMNAK
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE3 IADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPEVDIWSSGVILYALLCGTLPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_996 IADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPEVDIWSSGVILYALLCGTLPF
190 200 210 220 230 240
230 240 250 260 270 280
pF1KE3 DDDHVPTLFKKICDGIFYTPQYLNPSVISLLKHMLQVDPMKRATIKDIREHEWFKQDLPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_996 DDDHVPTLFKKICDGIFYTPQYLNPSVISLLKHMLQVDPMKRATIKDIREHEWFKQDLPK
250 260 270 280 290 300
290 300 310 320 330 340
pF1KE3 YLFPEDPSYSSTMIDDEALKEVCEKFECSEEEVLSCLYNRNHQDPLAVAYHLIIDNRRIM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_996 YLFPEDPSYSSTMIDDEALKEVCEKFECSEEEVLSCLYNRNHQDPLAVAYHLIIDNRRIM
310 320 330 340 350 360
350 360 370 380 390 400
pF1KE3 NEAKDFYLATSPPDSFLDDHHLTRPHPERVPFLVAETPRARHTLDELNPQKSKHQGVRKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_996 NEAKDFYLATSPPDSFLDDHHLTRPHPERVPFLVAETPRARHTLDELNPQKSKHQGVRKA
370 380 390 400 410 420
410 420 430 440 450 460
pF1KE3 KWHLGIRSQSRPNDIMAEVCRAIKQLDYEWKVVNPYYLRVRRKNPVTSTYSKMSLQLYQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_996 KWHLGIRSQSRPNDIMAEVCRAIKQLDYEWKVVNPYYLRVRRKNPVTSTYSKMSLQLYQV
430 440 450 460 470 480
470 480 490 500 510 520
pF1KE3 DSRTYLLDFRSIDDEITEAKSGTATPQRSGSVSNYRSCQRSDSDAEAQGKSSEVSLTSSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_996 DSRTYLLDFRSIDDEITEAKSGTATPQRSGSVSNYRSCQRSDSDAEAQGKSSEVSLTSSV
490 500 510 520 530 540
530 540 550
pF1KE3 TSLDSSPVDLTPRPGSHTIEFFEMCANLIKILAQ
::::::::::::::::::::::::::::::::::
NP_996 TSLDSSPVDLTPRPGSHTIEFFEMCANLIKILAQ
550 560 570
>>XP_016865113 (OMIM: 602739) PREDICTED: 5'-AMP-activate (548 aa)
initn: 3467 init1: 2963 opt: 2980 Z-score: 1392.4 bits: 267.5 E(85289): 8.1e-71
Smith-Waterman score: 3441; 97.2% identity (97.2% similar) in 532 aa overlap (43-559:17-548)
20 30 40 50 60 70
pF1KE3 AEKQKHDGRVKIGHYILGDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKI
::::::::::::::::::::::::::::::
XP_016 MQVKNIRKLPCQIIQSVGKHELTGHKVAVKILNRQKIRSLDVVGKI
10 20 30 40
80 90 100 110 120
pF1KE3 RREIQNLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGR-----------
:::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RREIQNLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRKSDVPGVVKTG
50 60 70 80 90 100
130 140 150 160 170
pF1KE3 ----LDEKESRRLFQQILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 STKELDEKESRRLFQQILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSD
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE3 GEFLRTSCGSPNYAAPEVISGRLYAGPEVDIWSSGVILYALLCGTLPFDDDHVPTLFKKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GEFLRTSCGSPNYAAPEVISGRLYAGPEVDIWSSGVILYALLCGTLPFDDDHVPTLFKKI
170 180 190 200 210 220
240 250 260 270 280 290
pF1KE3 CDGIFYTPQYLNPSVISLLKHMLQVDPMKRATIKDIREHEWFKQDLPKYLFPEDPSYSST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CDGIFYTPQYLNPSVISLLKHMLQVDPMKRATIKDIREHEWFKQDLPKYLFPEDPSYSST
230 240 250 260 270 280
300 310 320 330 340 350
pF1KE3 MIDDEALKEVCEKFECSEEEVLSCLYNRNHQDPLAVAYHLIIDNRRIMNEAKDFYLATSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MIDDEALKEVCEKFECSEEEVLSCLYNRNHQDPLAVAYHLIIDNRRIMNEAKDFYLATSP
290 300 310 320 330 340
360 370 380 390 400 410
pF1KE3 PDSFLDDHHLTRPHPERVPFLVAETPRARHTLDELNPQKSKHQGVRKAKWHLGIRSQSRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PDSFLDDHHLTRPHPERVPFLVAETPRARHTLDELNPQKSKHQGVRKAKWHLGIRSQSRP
350 360 370 380 390 400
420 430 440 450 460 470
pF1KE3 NDIMAEVCRAIKQLDYEWKVVNPYYLRVRRKNPVTSTYSKMSLQLYQVDSRTYLLDFRSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NDIMAEVCRAIKQLDYEWKVVNPYYLRVRRKNPVTSTYSKMSLQLYQVDSRTYLLDFRSI
410 420 430 440 450 460
480 490 500 510 520 530
pF1KE3 DDEITEAKSGTATPQRSGSVSNYRSCQRSDSDAEAQGKSSEVSLTSSVTSLDSSPVDLTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DDEITEAKSGTATPQRSGSVSNYRSCQRSDSDAEAQGKSSEVSLTSSVTSLDSSPVDLTP
470 480 490 500 510 520
540 550
pF1KE3 RPGSHTIEFFEMCANLIKILAQ
::::::::::::::::::::::
XP_016 RPGSHTIEFFEMCANLIKILAQ
530 540
>>NP_006243 (OMIM: 600497) 5'-AMP-activated protein kina (552 aa)
initn: 2851 init1: 2081 opt: 2829 Z-score: 1323.6 bits: 254.7 E(85289): 5.5e-67
Smith-Waterman score: 2829; 76.1% identity (90.4% similar) in 553 aa overlap (13-559:2-552)
10 20 30 40 50 60
pF1KE3 MRRLSSWRKMATAEKQKHDGRVKIGHYILGDTLGVGTFGKVKVGKHELTGHKVAVKILNR
:::::::::::::::.::::::::::::::.:.:.:::::::::::::
NP_006 MAEKQKHDGRVKIGHYVLGDTLGVGTFGKVKIGEHQLTGHKVAVKILNR
10 20 30 40
70 80 90 100 110 120
pF1KE3 QKIRSLDVVGKIRREIQNLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNG
::::::::::::.::::::::::::::::::::::::.:.::::::::::::::::::.:
NP_006 QKIRSLDVVGKIKREIQNLKLFRHPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHG
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE3 RLDEKESRRLFQQILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEF
:..: :.:::::::::.:::::::::::::::::::::::::::::::::::::::::::
NP_006 RVEEMEARRLFQQILSAVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEF
110 120 130 140 150 160
190 200 210 220 230 240
pF1KE3 LRTSCGSPNYAAPEVISGRLYAGPEVDIWSSGVILYALLCGTLPFDDDHVPTLFKKICDG
:::::::::::::::::::::::::::::: ::::::::::::::::.::::::::: :
NP_006 LRTSCGSPNYAAPEVISGRLYAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGG
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE3 IFYTPQYLNPSVISLLKHMLQVDPMKRATIKDIREHEWFKQDLPKYLFPEDPSYSSTMID
.:: :.::: :: .:: :::::::.:::::::::::::::::::.:::::::::....::
NP_006 VFYIPEYLNRSVATLLMHMLQVDPLKRATIKDIREHEWFKQDLPSYLFPEDPSYDANVID
230 240 250 260 270 280
310 320 330 340 350
pF1KE3 DEALKEVCEKFECSEEEVLSCLYNRNHQDPLAVAYHLIIDNRRIMNEAKDFYLATSPPD-
:::.:::::::::.: ::.. ::. . :: ::::::::::::::::.:..::::.:::.
NP_006 DEAVKEVCEKFECTESEVMNSLYSGDPQDQLAVAYHLIIDNRRIMNQASEFYLASSPPSG
290 300 310 320 330 340
360 370 380 390 400 410
pF1KE3 SFLDDH--HLT---RPHPERVPFLVAETPRARHTLDELNPQKSKHQGVRKAKWHLGIRSQ
::.:: :. .:::::.: :.:..:.:: :: :: : : .:.:::::::::::
NP_006 SFMDDSAMHIPPGLKPHPERMPPLIADSPKARCPLDALNTTKPKSLAVKKAKWHLGIRSQ
350 360 370 380 390 400
420 430 440 450 460 470
pF1KE3 SRPNDIMAEVCRAIKQLDYEWKVVNPYYLRVRRKNPVTSTYSKMSLQLYQVDSRTYLLDF
:.: :::::: ::.::::.:::::: :.::::::::::..: ::::::: ::.:.:::::
NP_006 SKPYDIMAEVYRAMKQLDFEWKVVNAYHLRVRRKNPVTGNYVKMSLQLYLVDNRSYLLDF
410 420 430 440 450 460
480 490 500 510 520 530
pF1KE3 RSIDDEITEAKSGTATPQRSGSVSNYRSCQRSDSDAEAQGKSSEVSLTSSVTSLDSSPVD
.:::::..: .::..::::: :... . . : ... :...: :::.:.:. :. .
NP_006 KSIDDEVVEQRSGSSTPQRSCSAAGLHRPRSSFDSTTAESHSLSGSLTGSLTG--STLSS
470 480 490 500 510 520
540 550
pF1KE3 LTPRPGSHTIEFFEMCANLIKILAQ
..:: ::::..::::::.:: ::.
NP_006 VSPRLGSHTMDFFEMCASLITTLAR
530 540 550
>>XP_016857182 (OMIM: 600497) PREDICTED: 5'-AMP-activate (462 aa)
initn: 2296 init1: 1526 opt: 2274 Z-score: 1071.1 bits: 207.8 E(85289): 6.3e-53
Smith-Waterman score: 2274; 73.1% identity (88.6% similar) in 464 aa overlap (102-559:1-462)
80 90 100 110 120 130
pF1KE3 IRREIQNLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLF
:::::::::::::::::.::..: :.::::
XP_016 MVMEYVSGGELFDYICKHGRVEEMEARRLF
10 20 30
140 150 160 170 180 190
pF1KE3 QQILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYA
:::::.::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QQILSAVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYA
40 50 60 70 80 90
200 210 220 230 240 250
pF1KE3 APEVISGRLYAGPEVDIWSSGVILYALLCGTLPFDDDHVPTLFKKICDGIFYTPQYLNPS
::::::::::::::::::: ::::::::::::::::.::::::::: :.:: :.::: :
XP_016 APEVISGRLYAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPEYLNRS
100 110 120 130 140 150
260 270 280 290 300 310
pF1KE3 VISLLKHMLQVDPMKRATIKDIREHEWFKQDLPKYLFPEDPSYSSTMIDDEALKEVCEKF
: .:: :::::::.:::::::::::::::::::.:::::::::....:::::.:::::::
XP_016 VATLLMHMLQVDPLKRATIKDIREHEWFKQDLPSYLFPEDPSYDANVIDDEAVKEVCEKF
160 170 180 190 200 210
320 330 340 350 360
pF1KE3 ECSEEEVLSCLYNRNHQDPLAVAYHLIIDNRRIMNEAKDFYLATSPPD-SFLDDH--HLT
::.: ::.. ::. . :: ::::::::::::::::.:..::::.:::. ::.:: :.
XP_016 ECTESEVMNSLYSGDPQDQLAVAYHLIIDNRRIMNQASEFYLASSPPSGSFMDDSAMHIP
220 230 240 250 260 270
370 380 390 400 410 420
pF1KE3 ---RPHPERVPFLVAETPRARHTLDELNPQKSKHQGVRKAKWHLGIRSQSRPNDIMAEVC
.:::::.: :.:..:.:: :: :: : : .:.::::::::::::.: ::::::
XP_016 PGLKPHPERMPPLIADSPKARCPLDALNTTKPKSLAVKKAKWHLGIRSQSKPYDIMAEVY
280 290 300 310 320 330
430 440 450 460 470 480
pF1KE3 RAIKQLDYEWKVVNPYYLRVRRKNPVTSTYSKMSLQLYQVDSRTYLLDFRSIDDEITEAK
::.::::.:::::: :.::::::::::..: ::::::: ::.:.:::::.:::::..: .
XP_016 RAMKQLDFEWKVVNAYHLRVRRKNPVTGNYVKMSLQLYLVDNRSYLLDFKSIDDEVVEQR
340 350 360 370 380 390
490 500 510 520 530 540
pF1KE3 SGTATPQRSGSVSNYRSCQRSDSDAEAQGKSSEVSLTSSVTSLDSSPVDLTPRPGSHTIE
::..::::: :... . . : ... :...: :::.:.:. :. ...:: ::::..
XP_016 SGSSTPQRSCSAAGLHRPRSSFDSTTAESHSLSGSLTGSLTG--STLSSVSPRLGSHTMD
400 410 420 430 440
550
pF1KE3 FFEMCANLIKILAQ
::::::.:: ::.
XP_016 FFEMCASLITTLAR
450 460
>>XP_016857183 (OMIM: 600497) PREDICTED: 5'-AMP-activate (462 aa)
initn: 2296 init1: 1526 opt: 2274 Z-score: 1071.1 bits: 207.8 E(85289): 6.3e-53
Smith-Waterman score: 2274; 73.1% identity (88.6% similar) in 464 aa overlap (102-559:1-462)
80 90 100 110 120 130
pF1KE3 IRREIQNLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLF
:::::::::::::::::.::..: :.::::
XP_016 MVMEYVSGGELFDYICKHGRVEEMEARRLF
10 20 30
140 150 160 170 180 190
pF1KE3 QQILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYA
:::::.::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QQILSAVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYA
40 50 60 70 80 90
200 210 220 230 240 250
pF1KE3 APEVISGRLYAGPEVDIWSSGVILYALLCGTLPFDDDHVPTLFKKICDGIFYTPQYLNPS
::::::::::::::::::: ::::::::::::::::.::::::::: :.:: :.::: :
XP_016 APEVISGRLYAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPEYLNRS
100 110 120 130 140 150
260 270 280 290 300 310
pF1KE3 VISLLKHMLQVDPMKRATIKDIREHEWFKQDLPKYLFPEDPSYSSTMIDDEALKEVCEKF
: .:: :::::::.:::::::::::::::::::.:::::::::....:::::.:::::::
XP_016 VATLLMHMLQVDPLKRATIKDIREHEWFKQDLPSYLFPEDPSYDANVIDDEAVKEVCEKF
160 170 180 190 200 210
320 330 340 350 360
pF1KE3 ECSEEEVLSCLYNRNHQDPLAVAYHLIIDNRRIMNEAKDFYLATSPPD-SFLDDH--HLT
::.: ::.. ::. . :: ::::::::::::::::.:..::::.:::. ::.:: :.
XP_016 ECTESEVMNSLYSGDPQDQLAVAYHLIIDNRRIMNQASEFYLASSPPSGSFMDDSAMHIP
220 230 240 250 260 270
370 380 390 400 410 420
pF1KE3 ---RPHPERVPFLVAETPRARHTLDELNPQKSKHQGVRKAKWHLGIRSQSRPNDIMAEVC
.:::::.: :.:..:.:: :: :: : : .:.::::::::::::.: ::::::
XP_016 PGLKPHPERMPPLIADSPKARCPLDALNTTKPKSLAVKKAKWHLGIRSQSKPYDIMAEVY
280 290 300 310 320 330
430 440 450 460 470 480
pF1KE3 RAIKQLDYEWKVVNPYYLRVRRKNPVTSTYSKMSLQLYQVDSRTYLLDFRSIDDEITEAK
::.::::.:::::: :.::::::::::..: ::::::: ::.:.:::::.:::::..: .
XP_016 RAMKQLDFEWKVVNAYHLRVRRKNPVTGNYVKMSLQLYLVDNRSYLLDFKSIDDEVVEQR
340 350 360 370 380 390
490 500 510 520 530 540
pF1KE3 SGTATPQRSGSVSNYRSCQRSDSDAEAQGKSSEVSLTSSVTSLDSSPVDLTPRPGSHTIE
::..::::: :... . . : ... :...: :::.:.:. :. ...:: ::::..
XP_016 SGSSTPQRSCSAAGLHRPRSSFDSTTAESHSLSGSLTGSLTG--STLSSVSPRLGSHTMD
400 410 420 430 440
550
pF1KE3 FFEMCANLIKILAQ
::::::.:: ::.
XP_016 FFEMCASLITTLAR
450 460
>>XP_016857181 (OMIM: 600497) PREDICTED: 5'-AMP-activate (462 aa)
initn: 2296 init1: 1526 opt: 2274 Z-score: 1071.1 bits: 207.8 E(85289): 6.3e-53
Smith-Waterman score: 2274; 73.1% identity (88.6% similar) in 464 aa overlap (102-559:1-462)
80 90 100 110 120 130
pF1KE3 IRREIQNLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLF
:::::::::::::::::.::..: :.::::
XP_016 MVMEYVSGGELFDYICKHGRVEEMEARRLF
10 20 30
140 150 160 170 180 190
pF1KE3 QQILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYA
:::::.::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QQILSAVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYA
40 50 60 70 80 90
200 210 220 230 240 250
pF1KE3 APEVISGRLYAGPEVDIWSSGVILYALLCGTLPFDDDHVPTLFKKICDGIFYTPQYLNPS
::::::::::::::::::: ::::::::::::::::.::::::::: :.:: :.::: :
XP_016 APEVISGRLYAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGGVFYIPEYLNRS
100 110 120 130 140 150
260 270 280 290 300 310
pF1KE3 VISLLKHMLQVDPMKRATIKDIREHEWFKQDLPKYLFPEDPSYSSTMIDDEALKEVCEKF
: .:: :::::::.:::::::::::::::::::.:::::::::....:::::.:::::::
XP_016 VATLLMHMLQVDPLKRATIKDIREHEWFKQDLPSYLFPEDPSYDANVIDDEAVKEVCEKF
160 170 180 190 200 210
320 330 340 350 360
pF1KE3 ECSEEEVLSCLYNRNHQDPLAVAYHLIIDNRRIMNEAKDFYLATSPPD-SFLDDH--HLT
::.: ::.. ::. . :: ::::::::::::::::.:..::::.:::. ::.:: :.
XP_016 ECTESEVMNSLYSGDPQDQLAVAYHLIIDNRRIMNQASEFYLASSPPSGSFMDDSAMHIP
220 230 240 250 260 270
370 380 390 400 410 420
pF1KE3 ---RPHPERVPFLVAETPRARHTLDELNPQKSKHQGVRKAKWHLGIRSQSRPNDIMAEVC
.:::::.: :.:..:.:: :: :: : : .:.::::::::::::.: ::::::
XP_016 PGLKPHPERMPPLIADSPKARCPLDALNTTKPKSLAVKKAKWHLGIRSQSKPYDIMAEVY
280 290 300 310 320 330
430 440 450 460 470 480
pF1KE3 RAIKQLDYEWKVVNPYYLRVRRKNPVTSTYSKMSLQLYQVDSRTYLLDFRSIDDEITEAK
::.::::.:::::: :.::::::::::..: ::::::: ::.:.:::::.:::::..: .
XP_016 RAMKQLDFEWKVVNAYHLRVRRKNPVTGNYVKMSLQLYLVDNRSYLLDFKSIDDEVVEQR
340 350 360 370 380 390
490 500 510 520 530 540
pF1KE3 SGTATPQRSGSVSNYRSCQRSDSDAEAQGKSSEVSLTSSVTSLDSSPVDLTPRPGSHTIE
::..::::: :... . . : ... :...: :::.:.:. :. ...:: ::::..
XP_016 SGSSTPQRSCSAAGLHRPRSSFDSTTAESHSLSGSLTGSLTG--STLSSVSPRLGSHTMD
400 410 420 430 440
550
pF1KE3 FFEMCANLIKILAQ
::::::.:: ::.
XP_016 FFEMCASLITTLAR
450 460
>>XP_006714545 (OMIM: 602739) PREDICTED: 5'-AMP-activate (301 aa)
initn: 2022 init1: 2022 opt: 2022 Z-score: 957.7 bits: 186.1 E(85289): 1.3e-46
Smith-Waterman score: 2022; 100.0% identity (100.0% similar) in 301 aa overlap (259-559:1-301)
230 240 250 260 270 280
pF1KE3 HVPTLFKKICDGIFYTPQYLNPSVISLLKHMLQVDPMKRATIKDIREHEWFKQDLPKYLF
::::::::::::::::::::::::::::::
XP_006 MLQVDPMKRATIKDIREHEWFKQDLPKYLF
10 20 30
290 300 310 320 330 340
pF1KE3 PEDPSYSSTMIDDEALKEVCEKFECSEEEVLSCLYNRNHQDPLAVAYHLIIDNRRIMNEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PEDPSYSSTMIDDEALKEVCEKFECSEEEVLSCLYNRNHQDPLAVAYHLIIDNRRIMNEA
40 50 60 70 80 90
350 360 370 380 390 400
pF1KE3 KDFYLATSPPDSFLDDHHLTRPHPERVPFLVAETPRARHTLDELNPQKSKHQGVRKAKWH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KDFYLATSPPDSFLDDHHLTRPHPERVPFLVAETPRARHTLDELNPQKSKHQGVRKAKWH
100 110 120 130 140 150
410 420 430 440 450 460
pF1KE3 LGIRSQSRPNDIMAEVCRAIKQLDYEWKVVNPYYLRVRRKNPVTSTYSKMSLQLYQVDSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LGIRSQSRPNDIMAEVCRAIKQLDYEWKVVNPYYLRVRRKNPVTSTYSKMSLQLYQVDSR
160 170 180 190 200 210
470 480 490 500 510 520
pF1KE3 TYLLDFRSIDDEITEAKSGTATPQRSGSVSNYRSCQRSDSDAEAQGKSSEVSLTSSVTSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TYLLDFRSIDDEITEAKSGTATPQRSGSVSNYRSCQRSDSDAEAQGKSSEVSLTSSVTSL
220 230 240 250 260 270
530 540 550
pF1KE3 DSSPVDLTPRPGSHTIEFFEMCANLIKILAQ
:::::::::::::::::::::::::::::::
XP_006 DSSPVDLTPRPGSHTIEFFEMCANLIKILAQ
280 290 300
>>NP_056006 (OMIM: 608973) serine/threonine-protein kina (926 aa)
initn: 978 init1: 824 opt: 976 Z-score: 477.1 bits: 98.8 E(85289): 7.8e-20
Smith-Waterman score: 977; 40.2% identity (71.9% similar) in 381 aa overlap (10-386:3-367)
10 20 30 40 50 60
pF1KE3 MRRLSSWRKMATAEKQKHDGRVKIGHYILGDTLGVGTFGKVKVGKHELTGHKVAVKILNR
:: . .. . : :..: : . ::: :.:. ::.:.:..: .::.::...
NP_056 MVMADGPRHLQRGPVRVGFYDIEGTLGKGNFAVVKLGRHRITKTEVAIKIIDK
10 20 30 40 50
70 80 90 100 110 120
pF1KE3 QKIRSLDVVGKIRREIQNLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNG
... .... :: ::.: .:.. ::::::::::. : : ...: ::...::.:::. ..:
NP_056 SQLDAVNLE-KIYREVQIMKMLDHPHIIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHG
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE3 RLDEKESRRLFQQILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEF
::.:.:.:: : ::::.::::: . .:::::: ::.::: .:: ::::::..:....::.
NP_056 RLNESEARRKFWQILSAVDYCHGRKIVHRDLKAENLLLDNNMNIKIADFGFGNFFKSGEL
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE3 LRTSCGSPNYAAPEVISGRLYAGPEVDIWSSGVILYALLCGTLPFDDDHVPTLFKKICDG
: : :::: ::::::. :. : ::..:::: ::.::.:.::.:::: .: : ... .:
NP_056 LATWCGSPPYAAPEVFEGQQYEGPQLDIWSMGVVLYVLVCGALPFDGPTLPILRQRVLEG
180 190 200 210 220 230
250 260 270 280 290
pF1KE3 IFYTPQYLNPSVISLLKHMLQVDPMKRATIKDIREHEWFKQDLP---KYLFPEDPSYSST
: : ... . :...:: .:: :: :: .:.::.:. ..: :.:.. .
NP_056 RFRIPYFMSEDCEHLIRRMLVLDPSKRLTIAQIKEHKWMLIEVPVQRPVLYPQEQENEPS
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE3 MID-DEALKEVCEKFECSEEEVLSCLYNRNHQDPLAVAYHLIIDNRRIMNEAKDFYLATS
. . .: . .. ... ...... : :... . .:. : :... :. .. ..:
NP_056 IGEFNEQVLRLMHSLGIDQQKTIESLQNKSY-NHFAAIYFLLVE--RLKSHRSSF-----
300 310 320 330 340
360 370 380 390 400 410
pF1KE3 PPDSFLDDHHLTRPHPERVPFLVAETPRARHTLDELNPQKSKHQGVRKAKWHLGIRSQSR
: .. :: . .: : .:: :.
NP_056 PVEQRLDGR-------QRRPSTIAEQTVAKAQTVGLPVTMHSPNMRLLRSALLPQASNVE
350 360 370 380 390
559 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 07:03:58 2016 done: Sun Nov 6 07:03:59 2016
Total Scan time: 10.590 Total Display time: 0.100
Function used was FASTA [36.3.4 Apr, 2011]