Result of FASTA (omim) for
pFN21AE3760
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3760, 494 aa
1>>>pF1KE3760 494 - 494 aa - 494 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 10.9517+/-0.000343; mu= -5.2090+/- 0.022
mean_var=341.4743+/-69.510, 0's: 0 Z-trim(125.5): 7 B-trim: 0 in 0/58
Lambda= 0.069406
statistics sampled from 49293 (49315) to 49293 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.834), E-opt: 0.2 (0.578), width: 16
Scan time: 13.420
The best scores are: opt bits E(85289)
NP_008818 (OMIM: 612053) zinc finger protein 36, C ( 494) 3401 353.8 6.6e-97
NP_004917 (OMIM: 601064) zinc finger protein 36, C ( 338) 674 80.6 7.8e-15
NP_001231627 (OMIM: 601064) zinc finger protein 36 ( 338) 674 80.6 7.8e-15
NP_001231630 (OMIM: 601064) zinc finger protein 36 ( 407) 674 80.7 9e-15
NP_003398 (OMIM: 190700) tristetraprolin [Homo sap ( 332) 455 58.7 3.1e-08
>>NP_008818 (OMIM: 612053) zinc finger protein 36, C3H1 (494 aa)
initn: 3401 init1: 3401 opt: 3401 Z-score: 1860.8 bits: 353.8 E(85289): 6.6e-97
Smith-Waterman score: 3401; 100.0% identity (100.0% similar) in 494 aa overlap (1-494:1-494)
10 20 30 40 50 60
pF1KE3 MSTTLLSAFYDVDFLCKTEKSLANLNLNNMLDKKAVGTPVAAAPSSGFAPGFLRRHSASN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 MSTTLLSAFYDVDFLCKTEKSLANLNLNNMLDKKAVGTPVAAAPSSGFAPGFLRRHSASN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 LHALAHPAPSPGSCSPKFPGAANGSSCGSAAAGGPTSYGTLKEPSGGGGTALLNKENKFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 LHALAHPAPSPGSCSPKFPGAANGSSCGSAAAGGPTSYGTLKEPSGGGGTALLNKENKFR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 DRSFSENGDRSQHLLHLQQQQKGGGGSQINSTRYKTELCRPFEESGTCKYGEKCQFAHGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 DRSFSENGDRSQHLLHLQQQQKGGGGSQINSTRYKTELCRPFEESGTCKYGEKCQFAHGF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 HELRSLTRHPKYKTELCRTFHTIGFCPYGPRCHFIHNADERRPAPSGGASGDLRAFGTRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 HELRSLTRHPKYKTELCRTFHTIGFCPYGPRCHFIHNADERRPAPSGGASGDLRAFGTRD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 ALHLGFPREPRPKLHHSLSFSGFPSGHHQPPGGLESPLLLDSPTSRTPPPPSCSSASSCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 ALHLGFPREPRPKLHHSLSFSGFPSGHHQPPGGLESPLLLDSPTSRTPPPPSCSSASSCS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 SSASSCSSASAASTPSGAPTCCASAAAAAAAALLYGTGGAEDLLAPGAPCAACSSASCAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 SSASSCSSASAASTPSGAPTCCASAAAAAAAALLYGTGGAEDLLAPGAPCAACSSASCAN
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 NAFAFGPELSSLITPLAIQTHNFAAVAAAAYYRSQQQQQQQGLAPPAQPPAPPSATLPAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 NAFAFGPELSSLITPLAIQTHNFAAVAAAAYYRSQQQQQQQGLAPPAQPPAPPSATLPAG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 AAAPPSPPFSFQLPRRLSDSPVFDAPPSPPDSLSDRDSYLSGSLSSGSLSGSESPSLDPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_008 AAAPPSPPFSFQLPRRLSDSPVFDAPPSPPDSLSDRDSYLSGSLSSGSLSGSESPSLDPG
430 440 450 460 470 480
490
pF1KE3 RRLPIFSRLSISDD
::::::::::::::
NP_008 RRLPIFSRLSISDD
490
>>NP_004917 (OMIM: 601064) zinc finger protein 36, C3H1 (338 aa)
initn: 941 init1: 552 opt: 674 Z-score: 387.3 bits: 80.6 E(85289): 7.8e-15
Smith-Waterman score: 902; 43.1% identity (56.9% similar) in 501 aa overlap (1-494:1-338)
10 20 30 40 50
pF1KE3 MSTTLLSA-FYDV-DFLCKTEKSL---ANLNLNNMLDKKAVGTPVAAAPSSGFAPGFLRR
:.:::.:: ..:. . ::: .: : : . .::.::::::... :: ::
NP_004 MTTTLVSATIFDLSEVLCKGNKMLNYSAPSAGGCLLDRKAVGTPAGG--------GFPRR
10 20 30 40 50
60 70 80 90 100 110
pF1KE3 HSASNLHALAHPAPSPGSCSPKFPGAANGSSCGSAAAGGPTSYGTLKEPSGGGGTALLNK
::.. :: :: . .. :. : :. : :: ..
NP_004 HSVT--------LPSS-----KF----HQNQLLSSLKGEPA-------P------ALSSR
60 70 80
120 130 140 150 160 170
pF1KE3 ENKFRDRSFSENGDRSQHLLHLQQQQKGGGGSQINSTRYKTELCRPFEESGTCKYGEKCQ
...::::::::.:.: :: :.: ::.:.::.::::::::::::.:.::::.:::
NP_004 DSRFRDRSFSEGGER---LLPTQKQP---GGGQVNSSRYKTELCRPFEENGACKYGDKCQ
90 100 110 120 130
180 190 200 210 220 230
pF1KE3 FAHGFHELRSLTRHPKYKTELCRTFHTIGFCPYGPRCHFIHNADERRPAPSGGASGDLRA
::::.::::::::::::::::::::::::::::::::::::::.::: .:: :: :
NP_004 FAHGIHELRSLTRHPKYKTELCRTFHTIGFCPYGPRCHFIHNAEERRAL--AGAR-DLSA
140 150 160 170 180 190
240 250 260 270 280 290
pF1KE3 FGTRDALHLGFPREPRPKLHHSLSFSGFPSGHHQPPGGLESPLLLDSPTSRTPPPPSCSS
::.:.::.::.::::. . . ::::::: ::::
NP_004 --------------DRPRLQHSFSFAGFPSA----AATAAATGLLDSPTSITPPP-----
200 210 220 230
300 310 320 330 340 350
pF1KE3 ASSCSSSASSCSSASAASTPSGAPTCCASAAAAAAAALLYGTGGAEDLLAPGAPCAACSS
.: .:.::: :.: .
NP_004 -------------------------------------IL----SADDLL--GSP----TL
240
360 370 380 390 400 410
pF1KE3 ASCANNAFAFGP-ELSSLITPLAIQTHNFAAVAAAAYYRSQQQQQQQGLAPPAQPPAPPS
. .:: :::. ::.:: :: ::
NP_004 PDGTNNPFAFSSQELASL----------FA----------------------------PS
250 260
420 430 440 450 460 470
pF1KE3 ATLPAGAAAPPSPPFSFQLPRRLSDSP-VFDAPPSPPDSLSDRDSYLSGSLSSGSLSGSE
::.:.. : .: : : .:.:: .::.:::: :::::...:::.: :.: :::.
NP_004 MGLPGGGS-----PTTF-LFRPMSESPHMFDSPPSPQDSLSDQEGYLSSS--SSSHSGSD
270 280 290 300 310
480 490
pF1KE3 SPSLDPGRRLPIFSRLSISDD
::.:: .::::::::::::::
NP_004 SPTLDNSRRLPIFSRLSISDD
320 330
>>NP_001231627 (OMIM: 601064) zinc finger protein 36, C3 (338 aa)
initn: 941 init1: 552 opt: 674 Z-score: 387.3 bits: 80.6 E(85289): 7.8e-15
Smith-Waterman score: 902; 43.1% identity (56.9% similar) in 501 aa overlap (1-494:1-338)
10 20 30 40 50
pF1KE3 MSTTLLSA-FYDV-DFLCKTEKSL---ANLNLNNMLDKKAVGTPVAAAPSSGFAPGFLRR
:.:::.:: ..:. . ::: .: : : . .::.::::::... :: ::
NP_001 MTTTLVSATIFDLSEVLCKGNKMLNYSAPSAGGCLLDRKAVGTPAGG--------GFPRR
10 20 30 40 50
60 70 80 90 100 110
pF1KE3 HSASNLHALAHPAPSPGSCSPKFPGAANGSSCGSAAAGGPTSYGTLKEPSGGGGTALLNK
::.. :: :: . .. :. : :. : :: ..
NP_001 HSVT--------LPSS-----KF----HQNQLLSSLKGEPA-------P------ALSSR
60 70 80
120 130 140 150 160 170
pF1KE3 ENKFRDRSFSENGDRSQHLLHLQQQQKGGGGSQINSTRYKTELCRPFEESGTCKYGEKCQ
...::::::::.:.: :: :.: ::.:.::.::::::::::::.:.::::.:::
NP_001 DSRFRDRSFSEGGER---LLPTQKQP---GGGQVNSSRYKTELCRPFEENGACKYGDKCQ
90 100 110 120 130
180 190 200 210 220 230
pF1KE3 FAHGFHELRSLTRHPKYKTELCRTFHTIGFCPYGPRCHFIHNADERRPAPSGGASGDLRA
::::.::::::::::::::::::::::::::::::::::::::.::: .:: :: :
NP_001 FAHGIHELRSLTRHPKYKTELCRTFHTIGFCPYGPRCHFIHNAEERRAL--AGAR-DLSA
140 150 160 170 180 190
240 250 260 270 280 290
pF1KE3 FGTRDALHLGFPREPRPKLHHSLSFSGFPSGHHQPPGGLESPLLLDSPTSRTPPPPSCSS
::.:.::.::.::::. . . ::::::: ::::
NP_001 --------------DRPRLQHSFSFAGFPSA----AATAAATGLLDSPTSITPPP-----
200 210 220 230
300 310 320 330 340 350
pF1KE3 ASSCSSSASSCSSASAASTPSGAPTCCASAAAAAAAALLYGTGGAEDLLAPGAPCAACSS
.: .:.::: :.: .
NP_001 -------------------------------------IL----SADDLL--GSP----TL
240
360 370 380 390 400 410
pF1KE3 ASCANNAFAFGP-ELSSLITPLAIQTHNFAAVAAAAYYRSQQQQQQQGLAPPAQPPAPPS
. .:: :::. ::.:: :: ::
NP_001 PDGTNNPFAFSSQELASL----------FA----------------------------PS
250 260
420 430 440 450 460 470
pF1KE3 ATLPAGAAAPPSPPFSFQLPRRLSDSP-VFDAPPSPPDSLSDRDSYLSGSLSSGSLSGSE
::.:.. : .: : : .:.:: .::.:::: :::::...:::.: :.: :::.
NP_001 MGLPGGGS-----PTTF-LFRPMSESPHMFDSPPSPQDSLSDQEGYLSSS--SSSHSGSD
270 280 290 300 310
480 490
pF1KE3 SPSLDPGRRLPIFSRLSISDD
::.:: .::::::::::::::
NP_001 SPTLDNSRRLPIFSRLSISDD
320 330
>>NP_001231630 (OMIM: 601064) zinc finger protein 36, C3 (407 aa)
initn: 941 init1: 552 opt: 674 Z-score: 386.2 bits: 80.7 E(85289): 9e-15
Smith-Waterman score: 902; 43.1% identity (56.9% similar) in 501 aa overlap (1-494:70-407)
10 20
pF1KE3 MSTTLLSA-FYDV-DFLCKTEKSL---ANL
:.:::.:: ..:. . ::: .: : :
NP_001 GLQTGEAAPSPHRDLRDTPDPRPWLARTHRMTTTLVSATIFDLSEVLCKGNKMLNYSAPS
40 50 60 70 80 90
30 40 50 60 70 80
pF1KE3 NLNNMLDKKAVGTPVAAAPSSGFAPGFLRRHSASNLHALAHPAPSPGSCSPKFPGAANGS
. .::.::::::... :: ::::.. :: :: . .
NP_001 AGGCLLDRKAVGTPAGG--------GFPRRHSVT--------LPSS-----KF----HQN
100 110 120 130
90 100 110 120 130 140
pF1KE3 SCGSAAAGGPTSYGTLKEPSGGGGTALLNKENKFRDRSFSENGDRSQHLLHLQQQQKGGG
. :. : :. : :: .....::::::::.:.: :: :.: :
NP_001 QLLSSLKGEPA-------P------ALSSRDSRFRDRSFSEGGER---LLPTQKQP---G
140 150 160 170
150 160 170 180 190 200
pF1KE3 GSQINSTRYKTELCRPFEESGTCKYGEKCQFAHGFHELRSLTRHPKYKTELCRTFHTIGF
:.:.::.::::::::::::.:.::::.:::::::.:::::::::::::::::::::::::
NP_001 GGQVNSSRYKTELCRPFEENGACKYGDKCQFAHGIHELRSLTRHPKYKTELCRTFHTIGF
180 190 200 210 220 230
210 220 230 240 250 260
pF1KE3 CPYGPRCHFIHNADERRPAPSGGASGDLRAFGTRDALHLGFPREPRPKLHHSLSFSGFPS
:::::::::::::.::: .:: :: : ::.:.::.::.::::
NP_001 CPYGPRCHFIHNAEERRAL--AGAR-DLSA--------------DRPRLQHSFSFAGFPS
240 250 260 270
270 280 290 300 310 320
pF1KE3 GHHQPPGGLESPLLLDSPTSRTPPPPSCSSASSCSSSASSCSSASAASTPSGAPTCCASA
. . . ::::::: ::::
NP_001 A----AATAAATGLLDSPTSITPPP-----------------------------------
280 290
330 340 350 360 370 380
pF1KE3 AAAAAAALLYGTGGAEDLLAPGAPCAACSSASCANNAFAFGP-ELSSLITPLAIQTHNFA
.: .:.::: :.: . . .:: :::. ::.:: ::
NP_001 -------IL----SADDLL--GSP----TLPDGTNNPFAFSSQELASL----------FA
300 310 320 330
390 400 410 420 430 440
pF1KE3 AVAAAAYYRSQQQQQQQGLAPPAQPPAPPSATLPAGAAAPPSPPFSFQLPRRLSDSP-VF
:: ::.:.. : .: : : .:.:: .:
NP_001 ----------------------------PSMGLPGGGS-----PTTF-LFRPMSESPHMF
340 350
450 460 470 480 490
pF1KE3 DAPPSPPDSLSDRDSYLSGSLSSGSLSGSESPSLDPGRRLPIFSRLSISDD
:.:::: :::::...:::.: :.: :::.::.:: .::::::::::::::
NP_001 DSPPSPQDSLSDQEGYLSSS--SSSHSGSDSPTLDNSRRLPIFSRLSISDD
360 370 380 390 400
>>NP_003398 (OMIM: 190700) tristetraprolin [Homo sapiens (332 aa)
initn: 440 init1: 384 opt: 455 Z-score: 268.9 bits: 58.7 E(85289): 3.1e-08
Smith-Waterman score: 499; 45.6% identity (60.1% similar) in 193 aa overlap (152-339:108-273)
130 140 150 160 170 180
pF1KE3 RSFSENGDRSQHLLHLQQQQKGGGGSQINSTRYKTELCRPFEESGTCKYGEKCQFAHGFH
.:::::::: : ::: :.:: :::::::.
NP_003 PPPGFAPLAPRLGPELSPSPTSPTATSTTPSRYKTELCRTFSESGRCRYGAKCQFAHGLG
80 90 100 110 120 130
190 200 210 220 230 240
pF1KE3 ELRSLTRHPKYKTELCRTFHTIGFCPYGPRCHFIHNADERRPAPSGGASGDLRAFGTRDA
:::. .::::::::::. :. : :::: ::::::: .: ::
NP_003 ELRQANRHPKYKTELCHKFYLQGRCPYGSRCHFIHNPSEDLAAP----------------
140 150 160 170 180
250 260 270 280 290
pF1KE3 LHLGFPREPRPKLHHSLSFSGFPSGHHQ--PPGGLESPLLLDS---PTSRTPPPPSCSSA
: : : :..:.::::.:::.. :: :: .: : .: :.: .::::.
NP_003 ---GHP----PVLRQSISFSGLPSGRRTSPPPPGLAGPSLSSSSFSPSS-SPPPPGDLPL
190 200 210 220 230
300 310 320 330 340 350
pF1KE3 SSCSSSASSCSSASAASTPSGAPTCCASAAAAAAAALLYGTGGAEDLLAPGAPCAACSSA
: . ::. .. : :. :.:: : :. .. ::
NP_003 SPSAFSAAP-GTPLARRDPT--PVCCPSCRRATPISVWGPLGGLVRTPSVQSLGSDPDEY
240 250 260 270 280 290
360 370 380 390 400 410
pF1KE3 SCANNAFAFGPELSSLITPLAIQTHNFAAVAAAAYYRSQQQQQQQGLAPPAQPPAPPSAT
NP_003 ASSGSSLGGSDSPVFEAGVFAPPQPVAAPRRLPIFNRISVSE
300 310 320 330
494 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 07:09:15 2016 done: Sun Nov 6 07:09:17 2016
Total Scan time: 13.420 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]