Result of FASTA (omim) for
pFN21AE3759
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3759, 481 aa
1>>>pF1KE3759 481 - 481 aa - 481 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.2545+/-0.000337; mu= 14.1693+/- 0.021
mean_var=103.2482+/-20.605, 0's: 0 Z-trim(117.1): 6 B-trim: 277 in 1/58
Lambda= 0.126221
statistics sampled from 28832 (28838) to 28832 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.707), E-opt: 0.2 (0.338), width: 16
Scan time: 9.020
The best scores are: opt bits E(85289)
NP_060793 (OMIM: 612101) phosphatidylinositol 4-ki ( 481) 3306 612.6 7.5e-175
XP_005248231 (OMIM: 612101) PREDICTED: phosphatidy ( 476) 3253 603.0 6e-172
XP_005248232 (OMIM: 612101) PREDICTED: phosphatidy ( 385) 2670 496.7 4.6e-140
NP_060895 (OMIM: 609763) phosphatidylinositol 4-ki ( 479) 1852 347.8 3.8e-95
>>NP_060793 (OMIM: 612101) phosphatidylinositol 4-kinase (481 aa)
initn: 3306 init1: 3306 opt: 3306 Z-score: 3260.1 bits: 612.6 E(85289): 7.5e-175
Smith-Waterman score: 3306; 99.8% identity (99.8% similar) in 481 aa overlap (1-481:1-481)
10 20 30 40 50 60
pF1KE3 MEDPSEPDRLASADGGSPEEEEDGEREPLLPRIAWAHPRRGAPGSAVRLLDAAGEEGEAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 MEDPSEPDRLASADGGSPEEEEDGEREPLLPRIAWAHPRRGAPGSAVRLLDAAGEEGEAG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 DEELPLPPGDVGVSRSSPAELDRSRPAVSVTIGTSEMNAFLDDPEFADIMLRAEQAIEVG
::::::::::::::::: ::::::::::::::::::::::::::::::::::::::::::
NP_060 DEELPLPPGDVGVSRSSSAELDRSRPAVSVTIGTSEMNAFLDDPEFADIMLRAEQAIEVG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 IFPERISQGSSGSYFVKDPKRKIIGVFKPKSEEPYGQLNPKWTKYVHKVCCPCCFGRGCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 IFPERISQGSSGSYFVKDPKRKIIGVFKPKSEEPYGQLNPKWTKYVHKVCCPCCFGRGCL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 IPNQGYLSEAGAYLVDNKLHLSIVPKTKVVWLVSETFNYNAIDRAKSRGKKYALEKVPKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 IPNQGYLSEAGAYLVDNKLHLSIVPKTKVVWLVSETFNYNAIDRAKSRGKKYALEKVPKV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 GRKFHRIGLPPKIGSFQLFVEGYKEAEYWLRKFEADPLPENIRKQFQSQFERLVILDYII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 GRKFHRIGLPPKIGSFQLFVEGYKEAEYWLRKFEADPLPENIRKQFQSQFERLVILDYII
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 RNTDRGNDNWLVRYEKQKCEKEIDHKESKWIDDEEFLIKIAAIDNGLAFPFKHPDEWRAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 RNTDRGNDNWLVRYEKQKCEKEIDHKESKWIDDEEFLIKIAAIDNGLAFPFKHPDEWRAY
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 PFHWAWLPQAKVPFSEEIRNLILPYISDMNFVQDLCEDLYELFKTDKGFDKATFESQMSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 PFHWAWLPQAKVPFSEEIRNLILPYISDMNFVQDLCEDLYELFKTDKGFDKATFESQMSV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 MRGQILNLTQALRDGKSPFQLVQIPCVIVERSQGGSQGRIVHLSNSFTQTVNCRKPFFSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 MRGQILNLTQALRDGKSPFQLVQIPCVIVERSQGGSQGRIVHLSNSFTQTVNCRKPFFSS
430 440 450 460 470 480
pF1KE3 W
:
NP_060 W
>>XP_005248231 (OMIM: 612101) PREDICTED: phosphatidylino (476 aa)
initn: 1719 init1: 1719 opt: 3253 Z-score: 3208.0 bits: 603.0 E(85289): 6e-172
Smith-Waterman score: 3253; 98.8% identity (98.8% similar) in 481 aa overlap (1-481:1-476)
10 20 30 40 50 60
pF1KE3 MEDPSEPDRLASADGGSPEEEEDGEREPLLPRIAWAHPRRGAPGSAVRLLDAAGEEGEAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MEDPSEPDRLASADGGSPEEEEDGEREPLLPRIAWAHPRRGAPGSAVRLLDAAGEEGEAG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 DEELPLPPGDVGVSRSSPAELDRSRPAVSVTIGTSEMNAFLDDPEFADIMLRAEQAIEVG
::::::::::::::::: ::::::::::::::::::::::::::::::::::::::::::
XP_005 DEELPLPPGDVGVSRSSSAELDRSRPAVSVTIGTSEMNAFLDDPEFADIMLRAEQAIEVG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 IFPERISQGSSGSYFVKDPKRKIIGVFKPKSEEPYGQLNPKWTKYVHKVCCPCCFGRGCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IFPERISQGSSGSYFVKDPKRKIIGVFKPKSEEPYGQLNPKWTKYVHKVCCPCCFGRGCL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 IPNQGYLSEAGAYLVDNKLHLSIVPKTKVVWLVSETFNYNAIDRAKSRGKKYALEKVPKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IPNQGYLSEAGAYLVDNKLHLSIVPKTKVVWLVSETFNYNAIDRAKSRGKKYALEKVPKV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 GRKFHRIGLPPKIGSFQLFVEGYKEAEYWLRKFEADPLPENIRKQFQSQFERLVILDYII
:::::::::::: :::::::::::::::::::::::::::::::::::::::::::
XP_005 GRKFHRIGLPPK-----LFVEGYKEAEYWLRKFEADPLPENIRKQFQSQFERLVILDYII
250 260 270 280 290
310 320 330 340 350 360
pF1KE3 RNTDRGNDNWLVRYEKQKCEKEIDHKESKWIDDEEFLIKIAAIDNGLAFPFKHPDEWRAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RNTDRGNDNWLVRYEKQKCEKEIDHKESKWIDDEEFLIKIAAIDNGLAFPFKHPDEWRAY
300 310 320 330 340 350
370 380 390 400 410 420
pF1KE3 PFHWAWLPQAKVPFSEEIRNLILPYISDMNFVQDLCEDLYELFKTDKGFDKATFESQMSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PFHWAWLPQAKVPFSEEIRNLILPYISDMNFVQDLCEDLYELFKTDKGFDKATFESQMSV
360 370 380 390 400 410
430 440 450 460 470 480
pF1KE3 MRGQILNLTQALRDGKSPFQLVQIPCVIVERSQGGSQGRIVHLSNSFTQTVNCRKPFFSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MRGQILNLTQALRDGKSPFQLVQIPCVIVERSQGGSQGRIVHLSNSFTQTVNCRKPFFSS
420 430 440 450 460 470
pF1KE3 W
:
XP_005 W
>>XP_005248232 (OMIM: 612101) PREDICTED: phosphatidylino (385 aa)
initn: 2670 init1: 2670 opt: 2670 Z-score: 2635.5 bits: 496.7 E(85289): 4.6e-140
Smith-Waterman score: 2670; 100.0% identity (100.0% similar) in 385 aa overlap (97-481:1-385)
70 80 90 100 110 120
pF1KE3 PPGDVGVSRSSPAELDRSRPAVSVTIGTSEMNAFLDDPEFADIMLRAEQAIEVGIFPERI
::::::::::::::::::::::::::::::
XP_005 MNAFLDDPEFADIMLRAEQAIEVGIFPERI
10 20 30
130 140 150 160 170 180
pF1KE3 SQGSSGSYFVKDPKRKIIGVFKPKSEEPYGQLNPKWTKYVHKVCCPCCFGRGCLIPNQGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SQGSSGSYFVKDPKRKIIGVFKPKSEEPYGQLNPKWTKYVHKVCCPCCFGRGCLIPNQGY
40 50 60 70 80 90
190 200 210 220 230 240
pF1KE3 LSEAGAYLVDNKLHLSIVPKTKVVWLVSETFNYNAIDRAKSRGKKYALEKVPKVGRKFHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LSEAGAYLVDNKLHLSIVPKTKVVWLVSETFNYNAIDRAKSRGKKYALEKVPKVGRKFHR
100 110 120 130 140 150
250 260 270 280 290 300
pF1KE3 IGLPPKIGSFQLFVEGYKEAEYWLRKFEADPLPENIRKQFQSQFERLVILDYIIRNTDRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IGLPPKIGSFQLFVEGYKEAEYWLRKFEADPLPENIRKQFQSQFERLVILDYIIRNTDRG
160 170 180 190 200 210
310 320 330 340 350 360
pF1KE3 NDNWLVRYEKQKCEKEIDHKESKWIDDEEFLIKIAAIDNGLAFPFKHPDEWRAYPFHWAW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NDNWLVRYEKQKCEKEIDHKESKWIDDEEFLIKIAAIDNGLAFPFKHPDEWRAYPFHWAW
220 230 240 250 260 270
370 380 390 400 410 420
pF1KE3 LPQAKVPFSEEIRNLILPYISDMNFVQDLCEDLYELFKTDKGFDKATFESQMSVMRGQIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LPQAKVPFSEEIRNLILPYISDMNFVQDLCEDLYELFKTDKGFDKATFESQMSVMRGQIL
280 290 300 310 320 330
430 440 450 460 470 480
pF1KE3 NLTQALRDGKSPFQLVQIPCVIVERSQGGSQGRIVHLSNSFTQTVNCRKPFFSSW
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NLTQALRDGKSPFQLVQIPCVIVERSQGGSQGRIVHLSNSFTQTVNCRKPFFSSW
340 350 360 370 380
>>NP_060895 (OMIM: 609763) phosphatidylinositol 4-kinase (479 aa)
initn: 1925 init1: 1172 opt: 1852 Z-score: 1829.2 bits: 347.8 E(85289): 3.8e-95
Smith-Waterman score: 1890; 59.8% identity (78.6% similar) in 490 aa overlap (17-481:9-479)
10 20 30 40 50
pF1KE3 MEDPSEPDRLASADGGSPEEEEDGEREPLLPRIAWAH-PRRGAPGSAVRLLDAAGEEGEA
:::. . . .: . :: :. .::.:::. ::: .
NP_060 MDETSPLVSPERAQPPDY--TFPSGSGAHFPQ--VPGGAVRVAAAAG----S
10 20 30 40
60 70 80 90
pF1KE3 GDEELPLPPGDVGVSRSSPAELDRSRPAV----SVTIGTS-------------------E
: : :::. : .: :::.: :. . :.... :
NP_060 G----PSPPGSPGHDRERQPLLDRARGAAAQGQTQTVAAQAQALAAQAAAAAHAAQAHRE
50 60 70 80 90 100
100 110 120 130 140 150
pF1KE3 MNAFLDDPEFADIMLRAEQAIEVGIFPERISQGSSGSYFVKDPKRKIIGVFKPKSEEPYG
: : .:::: .. .:: ::: :::::: ::::::::::::. .::.:::::.:::::
NP_060 RNEFPEDPEFEAVVRQAELAIERCIFPERIYQGSSGSYFVKDPQGRIIAVFKPKNEEPYG
110 120 130 140 150 160
160 170 180 190 200 210
pF1KE3 QLNPKWTKYVHKVCCPCCFGRGCLIPNQGYLSEAGAYLVDNKLHLSIVPKTKVVWLVSET
.:::::::...:.:::::::: ::. :::::::::: :::.::.:.:::.::::.:.:::
NP_060 HLNPKWTKWLQKLCCPCCFGRDCLVLNQGYLSEAGASLVDQKLELNIVPRTKVVYLASET
170 180 190 200 210 220
220 230 240 250 260 270
pF1KE3 FNYNAIDRAKSRGKKYALEKVPKVGRKFHRIGLPPKIGSFQLFVEGYKEAEYWLRKFEAD
:::.::::.:::::. :::::::::..:.:::::::.:::::::::::.:.::::.:::.
NP_060 FNYSAIDRVKSRGKRLALEKVPKVGQRFNRIGLPPKVGSFQLFVEGYKDADYWLRRFEAE
230 240 250 260 270 280
280 290 300 310 320 330
pF1KE3 PLPENIRKQFQSQFERLVILDYIIRNTDRGNDNWLVRYEKQKCEKEIDH-KESKWIDDEE
::::: .:. ::::::.::::::::::::::::..:. : . . ... :. .:
NP_060 PLPENTNRQLLLQFERLVVLDYIIRNTDRGNDNWLIKYD---CPMDSSSSRDTDWVVVKE
290 300 310 320 330
340 350 360 370 380 390
pF1KE3 FLIKIAAIDNGLAFPFKHPDEWRAYPFHWAWLPQAKVPFSEEIRNLILPYISDMNFVQDL
.::.::::::::::.:::: ::::::.::::::::::::.::..:::: ::: :::.::
NP_060 PVIKVAAIDNGLAFPLKHPDSWRAYPFYWAWLPQAKVPFSQEIKDLILPKISDPNFVKDL
340 350 360 370 380 390
400 410 420 430 440 450
pF1KE3 CEDLYELFKTDKGFDKATFESQMSVMRGQILNLTQALRDGKSPFQLVQIPCVIVERSQGG
:::::::: : :::.. :..:..:::::::::::::.:.:::..:::.: :::: ...
NP_060 EEDLYELFKKDPGFDRGQFHKQIAVMRGQILNLTQALKDNKSPLHLVQMPPVIVETARSH
400 410 420 430 440 450
460 470 480
pF1KE3 SQGRIVHLSNSFTQTVNCRKPFFSSW
... :.:.::. . :::::: :
NP_060 QRSS----SESYTQSFQSRKPFFSWW
460 470
481 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 07:05:24 2016 done: Sun Nov 6 07:05:25 2016
Total Scan time: 9.020 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]