Result of FASTA (omim) for
pFN21AE3723
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3723, 778 aa
1>>>pF1KE3723 778 - 778 aa - 778 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 13.2274+/-0.000619; mu= -17.0851+/- 0.038
mean_var=591.6942+/-132.564, 0's: 0 Z-trim(118.0): 2131 B-trim: 1267 in 1/57
Lambda= 0.052726
statistics sampled from 27948 (30541) to 27948 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.693), E-opt: 0.2 (0.358), width: 16
Scan time: 11.900
The best scores are: opt bits E(85289)
XP_011543093 (OMIM: 600526) PREDICTED: serine/thre ( 798) 4996 396.2 2.9e-109
XP_011543092 (OMIM: 600526) PREDICTED: serine/thre ( 799) 4984 395.3 5.5e-109
NP_059672 (OMIM: 600526) serine/threonine-protein ( 745) 4895 388.5 5.7e-107
XP_011543094 (OMIM: 600526) PREDICTED: serine/thre ( 793) 4882 387.5 1.2e-106
NP_001034558 (OMIM: 600526) serine/threonine-prote ( 788) 4212 336.5 2.6e-91
XP_016872799 (OMIM: 600526) PREDICTED: serine/thre ( 763) 4211 336.4 2.7e-91
XP_011543091 (OMIM: 600526) PREDICTED: serine/thre ( 808) 4098 327.9 1.1e-88
XP_011543095 (OMIM: 600526) PREDICTED: serine/thre ( 784) 4085 326.9 2.1e-88
NP_001156769 (OMIM: 600526) serine/threonine-prote ( 709) 3306 267.6 1.3e-70
NP_004945 (OMIM: 600526) serine/threonine-protein ( 724) 3306 267.6 1.4e-70
NP_001156768 (OMIM: 600526) serine/threonine-prote ( 719) 3294 266.7 2.6e-70
XP_011543100 (OMIM: 600526) PREDICTED: serine/thre ( 729) 3192 258.9 5.6e-68
XP_016872800 (OMIM: 600526) PREDICTED: serine/thre ( 738) 3192 258.9 5.6e-68
XP_011543098 (OMIM: 600526) PREDICTED: serine/thre ( 744) 3192 258.9 5.7e-68
XP_011543096 (OMIM: 600526) PREDICTED: serine/thre ( 753) 3192 258.9 5.7e-68
XP_011543099 (OMIM: 600526) PREDICTED: serine/thre ( 739) 3180 258.0 1.1e-67
XP_011543097 (OMIM: 600526) PREDICTED: serine/thre ( 745) 3180 258.0 1.1e-67
NP_001273055 (OMIM: 606511) serine/threonine-prote ( 780) 2889 235.9 5.1e-61
XP_005273191 (OMIM: 606511) PREDICTED: serine/thre ( 781) 2860 233.7 2.3e-60
XP_016856796 (OMIM: 606511) PREDICTED: serine/thre ( 670) 2421 200.2 2.4e-50
NP_061120 (OMIM: 606511) serine/threonine-protein ( 795) 2372 196.6 3.5e-49
NP_001273053 (OMIM: 606511) serine/threonine-prote ( 796) 2327 193.1 3.8e-48
NP_002367 (OMIM: 602678) MAP/microtubule affinity- ( 729) 2277 189.3 5e-47
XP_005267698 (OMIM: 602678) PREDICTED: MAP/microtu ( 738) 2277 189.3 5e-47
NP_001122391 (OMIM: 602678) MAP/microtubule affini ( 744) 2277 189.3 5.1e-47
NP_001122390 (OMIM: 602678) MAP/microtubule affini ( 753) 2277 189.3 5.1e-47
XP_005267700 (OMIM: 602678) PREDICTED: MAP/microtu ( 643) 2259 187.9 1.2e-46
XP_011507863 (OMIM: 606511) PREDICTED: serine/thre ( 788) 2258 187.9 1.4e-46
NP_001273057 (OMIM: 606511) serine/threonine-prote ( 758) 2251 187.3 2e-46
XP_006720209 (OMIM: 602678) PREDICTED: MAP/microtu ( 739) 2203 183.7 2.5e-45
XP_016876781 (OMIM: 602678) PREDICTED: MAP/microtu ( 722) 2146 179.3 5e-44
XP_005267699 (OMIM: 602678) PREDICTED: MAP/microtu ( 737) 2144 179.2 5.6e-44
NP_001122392 (OMIM: 602678) MAP/microtubule affini ( 713) 2140 178.9 6.8e-44
XP_016876780 (OMIM: 602678) PREDICTED: MAP/microtu ( 728) 2140 178.9 6.9e-44
XP_016876782 (OMIM: 602678) PREDICTED: MAP/microtu ( 708) 2072 173.7 2.4e-42
NP_113605 (OMIM: 606495) MAP/microtubule affinity- ( 688) 2024 170.0 3e-41
NP_001186796 (OMIM: 606495) MAP/microtubule affini ( 752) 2017 169.5 4.6e-41
XP_016876787 (OMIM: 602678) PREDICTED: MAP/microtu ( 665) 1960 165.1 8.5e-40
XP_016876785 (OMIM: 602678) PREDICTED: MAP/microtu ( 674) 1960 165.2 8.6e-40
XP_016876784 (OMIM: 602678) PREDICTED: MAP/microtu ( 680) 1960 165.2 8.7e-40
XP_016876783 (OMIM: 602678) PREDICTED: MAP/microtu ( 689) 1960 165.2 8.7e-40
XP_011535071 (OMIM: 602678) PREDICTED: MAP/microtu ( 673) 1959 165.1 9.1e-40
XP_006711389 (OMIM: 606511) PREDICTED: serine/thre ( 708) 1905 161.0 1.6e-38
XP_016856795 (OMIM: 606511) PREDICTED: serine/thre ( 685) 1904 160.9 1.7e-38
XP_016856794 (OMIM: 606511) PREDICTED: serine/thre ( 686) 1859 157.5 1.8e-37
XP_011507864 (OMIM: 606511) PREDICTED: serine/thre ( 686) 1859 157.5 1.8e-37
XP_016876786 (OMIM: 602678) PREDICTED: MAP/microtu ( 673) 1827 155.0 9.5e-37
XP_016876788 (OMIM: 602678) PREDICTED: MAP/microtu ( 664) 1823 154.7 1.2e-36
XP_006723370 (OMIM: 606495) PREDICTED: MAP/microtu ( 685) 1758 149.8 3.7e-35
XP_016876793 (OMIM: 602678) PREDICTED: MAP/microtu ( 598) 1673 143.3 3e-33
>>XP_011543093 (OMIM: 600526) PREDICTED: serine/threonin (798 aa)
initn: 4995 init1: 4995 opt: 4996 Z-score: 2082.6 bits: 396.2 E(85289): 2.9e-109
Smith-Waterman score: 4996; 99.2% identity (99.5% similar) in 767 aa overlap (12-778:32-798)
10 20 30 40
pF1KE3 MSSARTPLPTLNERDTEQPTLGHLDSKPSSKSNMIRGRNSA
..: :::::::::::::::::::::::
XP_011 EVAGSPFPFLQSVACLLTLAHIPAVGNILQHRRRGAGPTLGHLDSKPSSKSNMIRGRNSA
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE3 TSADEQPHIGNYRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKLFREV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TSADEQPHIGNYRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKLFREV
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE3 RIMKVLNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RIMKVLNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVS
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE3 AVQYCHQKFIVHRDLKAENLLLDADMNIKIADFGFSNEFTFGNKLDTFCGSPPYAAPELF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AVQYCHQKFIVHRDLKAENLLLDADMNIKIADFGFSNEFTFGNKLDTFCGSPPYAAPELF
190 200 210 220 230 240
230 240 250 260 270 280
pF1KE3 QGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLL
250 260 270 280 290 300
290 300 310 320 330 340
pF1KE3 KKFLILNPSKRGTLEQIMKDRWMNVGHEDDELKPYVEPLPDYKDPRRTELMVSMGYTREE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KKFLILNPSKRGTLEQIMKDRWMNVGHEDDELKPYVEPLPDYKDPRRTELMVSMGYTREE
310 320 330 340 350 360
350 360 370 380 390 400
pF1KE3 IQDSLVGQRYNEVMATYLLLGYKSSELEGDTITLKPRPSADLTNSSAPSPSHKVQRSVSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IQDSLVGQRYNEVMATYLLLGYKSSELEGDTITLKPRPSADLTNSSAPSPSHKVQRSVSA
370 380 390 400 410 420
410 420 430 440 450 460
pF1KE3 NPKQRRFSDQAGPAIPTSNSYSKKTQSNNAENKRPEEDRESGRKASSTAKVPASPLPGLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NPKQRRFSDQAGPAIPTSNSYSKKTQSNNAENKRPEEDRESGRKASSTAKVPASPLPGLE
430 440 450 460 470 480
470 480 490 500 510 520
pF1KE3 RKKTTPTPSTNSVLSTSTNRSRNSPLLERASLGQASIQNGKDSLTMPGSRASTASASAAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RKKTTPTPSTNSVLSTSTNRSRNSPLLERASLGQASIQNGKDSLTMPGSRASTASASAAV
490 500 510 520 530 540
530 540 550 560 570 580
pF1KE3 SAARPRQHQKSMSASVHPNKASGLPPTESNCEVPRPSTAPQRVPVASPSAHNISSSGGAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SAARPRQHQKSMSASVHPNKASGLPPTESNCEVPRPSTAPQRVPVASPSAHNISSSGGAP
550 560 570 580 590 600
590 600 610 620 630 640
pF1KE3 DRTNFPRGVSSRSTFHAGQLRQVRDQQNLPYGVTPASPSGHSQGRRGASGSIFSKFTSKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DRTNFPRGVSSRSTFHAGQLRQVRDQQNLPYGVTPASPSGHSQGRRGASGSIFSKFTSKF
610 620 630 640 650 660
650 660 670 680 690 700
pF1KE3 VRRNLNEPESKDRVETLRPHVVGSGGNDKEKEEFREAKPRSLRFTWSMKTTSSMEPNEMM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VRRNLNEPESKDRVETLRPHVVGSGGNDKEKEEFREAKPRSLRFTWSMKTTSSMEPNEMM
670 680 690 700 710 720
710 720 730 740 750 760
pF1KE3 REIRKVLDANSCQSELHEKYMLLCMHGTPGHEDFVQWEMEVCKLPRLSLNGVRFKRISGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 REIRKVLDANSCQSELHEKYMLLCMHGTPGHEDFVQWEMEVCKLPRLSLNGVRFKRISGT
730 740 750 760 770 780
770
pF1KE3 SMAFKNIASKIANELKL
:::::::::::::::::
XP_011 SMAFKNIASKIANELKL
790
>>XP_011543092 (OMIM: 600526) PREDICTED: serine/threonin (799 aa)
initn: 2637 init1: 2601 opt: 4984 Z-score: 2077.6 bits: 395.3 E(85289): 5.5e-109
Smith-Waterman score: 4984; 99.1% identity (99.3% similar) in 768 aa overlap (12-778:32-799)
10 20 30 40
pF1KE3 MSSARTPLPTLNERDTEQPTLGHLDSKPSSKSNMIRGRNSA
..: :::::::::::::::::::::::
XP_011 EVAGSPFPFLQSVACLLTLAHIPAVGNILQHRRRGAGPTLGHLDSKPSSKSNMIRGRNSA
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE3 TSADEQPHIGNYRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKLFREV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TSADEQPHIGNYRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKLFREV
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE3 RIMKVLNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RIMKVLNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVS
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE3 AVQYCHQKFIVHRDLKAENLLLDADMNIKIADFGFSNEFTFGNKLDTFCGSPPYAAPELF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AVQYCHQKFIVHRDLKAENLLLDADMNIKIADFGFSNEFTFGNKLDTFCGSPPYAAPELF
190 200 210 220 230 240
230 240 250 260 270 280
pF1KE3 QGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLL
250 260 270 280 290 300
290 300 310 320 330 340
pF1KE3 KKFLILNPSKRGTLEQIMKDRWMNVGHEDDELKPYVEPLPDYKDPRRTELMVSMGYTREE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KKFLILNPSKRGTLEQIMKDRWMNVGHEDDELKPYVEPLPDYKDPRRTELMVSMGYTREE
310 320 330 340 350 360
350 360 370 380 390 400
pF1KE3 IQDSLVGQRYNEVMATYLLLGYKSSELEGDTITLKPRPSADLTNSSAPSPSHKVQRSVSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IQDSLVGQRYNEVMATYLLLGYKSSELEGDTITLKPRPSADLTNSSAPSPSHKVQRSVSA
370 380 390 400 410 420
410 420 430 440 450 460
pF1KE3 NPKQRRFSDQA-GPAIPTSNSYSKKTQSNNAENKRPEEDRESGRKASSTAKVPASPLPGL
::::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NPKQRRFSDQAAGPAIPTSNSYSKKTQSNNAENKRPEEDRESGRKASSTAKVPASPLPGL
430 440 450 460 470 480
470 480 490 500 510 520
pF1KE3 ERKKTTPTPSTNSVLSTSTNRSRNSPLLERASLGQASIQNGKDSLTMPGSRASTASASAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ERKKTTPTPSTNSVLSTSTNRSRNSPLLERASLGQASIQNGKDSLTMPGSRASTASASAA
490 500 510 520 530 540
530 540 550 560 570 580
pF1KE3 VSAARPRQHQKSMSASVHPNKASGLPPTESNCEVPRPSTAPQRVPVASPSAHNISSSGGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VSAARPRQHQKSMSASVHPNKASGLPPTESNCEVPRPSTAPQRVPVASPSAHNISSSGGA
550 560 570 580 590 600
590 600 610 620 630 640
pF1KE3 PDRTNFPRGVSSRSTFHAGQLRQVRDQQNLPYGVTPASPSGHSQGRRGASGSIFSKFTSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PDRTNFPRGVSSRSTFHAGQLRQVRDQQNLPYGVTPASPSGHSQGRRGASGSIFSKFTSK
610 620 630 640 650 660
650 660 670 680 690 700
pF1KE3 FVRRNLNEPESKDRVETLRPHVVGSGGNDKEKEEFREAKPRSLRFTWSMKTTSSMEPNEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FVRRNLNEPESKDRVETLRPHVVGSGGNDKEKEEFREAKPRSLRFTWSMKTTSSMEPNEM
670 680 690 700 710 720
710 720 730 740 750 760
pF1KE3 MREIRKVLDANSCQSELHEKYMLLCMHGTPGHEDFVQWEMEVCKLPRLSLNGVRFKRISG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MREIRKVLDANSCQSELHEKYMLLCMHGTPGHEDFVQWEMEVCKLPRLSLNGVRFKRISG
730 740 750 760 770 780
770
pF1KE3 TSMAFKNIASKIANELKL
::::::::::::::::::
XP_011 TSMAFKNIASKIANELKL
790
>>NP_059672 (OMIM: 600526) serine/threonine-protein kina (745 aa)
initn: 4895 init1: 4895 opt: 4895 Z-score: 2041.4 bits: 388.5 E(85289): 5.7e-107
Smith-Waterman score: 4895; 100.0% identity (100.0% similar) in 745 aa overlap (34-778:1-745)
10 20 30 40 50 60
pF1KE3 ARTPLPTLNERDTEQPTLGHLDSKPSSKSNMIRGRNSATSADEQPHIGNYRLLKTIGKGN
::::::::::::::::::::::::::::::
NP_059 MIRGRNSATSADEQPHIGNYRLLKTIGKGN
10 20 30
70 80 90 100 110 120
pF1KE3 FAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKLFREVRIMKVLNHPNIVKLFEVIETEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_059 FAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKLFREVRIMKVLNHPNIVKLFEVIETEK
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE3 TLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFIVHRDLKAENLLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_059 TLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFIVHRDLKAENLLL
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE3 DADMNIKIADFGFSNEFTFGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_059 DADMNIKIADFGFSNEFTFGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTL
160 170 180 190 200 210
250 260 270 280 290 300
pF1KE3 VSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLILNPSKRGTLEQIMKDRW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_059 VSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLILNPSKRGTLEQIMKDRW
220 230 240 250 260 270
310 320 330 340 350 360
pF1KE3 MNVGHEDDELKPYVEPLPDYKDPRRTELMVSMGYTREEIQDSLVGQRYNEVMATYLLLGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_059 MNVGHEDDELKPYVEPLPDYKDPRRTELMVSMGYTREEIQDSLVGQRYNEVMATYLLLGY
280 290 300 310 320 330
370 380 390 400 410 420
pF1KE3 KSSELEGDTITLKPRPSADLTNSSAPSPSHKVQRSVSANPKQRRFSDQAGPAIPTSNSYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_059 KSSELEGDTITLKPRPSADLTNSSAPSPSHKVQRSVSANPKQRRFSDQAGPAIPTSNSYS
340 350 360 370 380 390
430 440 450 460 470 480
pF1KE3 KKTQSNNAENKRPEEDRESGRKASSTAKVPASPLPGLERKKTTPTPSTNSVLSTSTNRSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_059 KKTQSNNAENKRPEEDRESGRKASSTAKVPASPLPGLERKKTTPTPSTNSVLSTSTNRSR
400 410 420 430 440 450
490 500 510 520 530 540
pF1KE3 NSPLLERASLGQASIQNGKDSLTMPGSRASTASASAAVSAARPRQHQKSMSASVHPNKAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_059 NSPLLERASLGQASIQNGKDSLTMPGSRASTASASAAVSAARPRQHQKSMSASVHPNKAS
460 470 480 490 500 510
550 560 570 580 590 600
pF1KE3 GLPPTESNCEVPRPSTAPQRVPVASPSAHNISSSGGAPDRTNFPRGVSSRSTFHAGQLRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_059 GLPPTESNCEVPRPSTAPQRVPVASPSAHNISSSGGAPDRTNFPRGVSSRSTFHAGQLRQ
520 530 540 550 560 570
610 620 630 640 650 660
pF1KE3 VRDQQNLPYGVTPASPSGHSQGRRGASGSIFSKFTSKFVRRNLNEPESKDRVETLRPHVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_059 VRDQQNLPYGVTPASPSGHSQGRRGASGSIFSKFTSKFVRRNLNEPESKDRVETLRPHVV
580 590 600 610 620 630
670 680 690 700 710 720
pF1KE3 GSGGNDKEKEEFREAKPRSLRFTWSMKTTSSMEPNEMMREIRKVLDANSCQSELHEKYML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_059 GSGGNDKEKEEFREAKPRSLRFTWSMKTTSSMEPNEMMREIRKVLDANSCQSELHEKYML
640 650 660 670 680 690
730 740 750 760 770
pF1KE3 LCMHGTPGHEDFVQWEMEVCKLPRLSLNGVRFKRISGTSMAFKNIASKIANELKL
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_059 LCMHGTPGHEDFVQWEMEVCKLPRLSLNGVRFKRISGTSMAFKNIASKIANELKL
700 710 720 730 740
>>XP_011543094 (OMIM: 600526) PREDICTED: serine/threonin (793 aa)
initn: 3434 init1: 2601 opt: 4882 Z-score: 2035.7 bits: 387.5 E(85289): 1.2e-106
Smith-Waterman score: 4882; 97.5% identity (98.2% similar) in 768 aa overlap (12-778:32-793)
10 20 30 40
pF1KE3 MSSARTPLPTLNERDTEQPTLGHLDSKPSSKSNMIRGRNSA
..: :::::::::::::::::::::::
XP_011 EVAGSPFPFLQSVACLLTLAHIPAVGNILQHRRRGAGPTLGHLDSKPSSKSNMIRGRNSA
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE3 TSADEQPHIGNYRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKLFREV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TSADEQPHIGNYRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKLFREV
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE3 RIMKVLNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RIMKVLNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVS
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE3 AVQYCHQKFIVHRDLKAENLLLDADMNIKIADFGFSNEFTFGNKLDTFCGSPPYAAPELF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AVQYCHQKFIVHRDLKAENLLLDADMNIKIADFGFSNEFTFGNKLDTFCGSPPYAAPELF
190 200 210 220 230 240
230 240 250 260 270 280
pF1KE3 QGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLL
250 260 270 280 290 300
290 300 310 320 330 340
pF1KE3 KKFLILNPSKRGTLEQIMKDRWMNVGHEDDELKPYVEPLPDYKDPRRTELMVSMGYTREE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KKFLILNPSKRGTLEQIMKDRWMNVGHEDDELKPYVEPLPDYKDPRRTELMVSMGYTREE
310 320 330 340 350 360
350 360 370 380 390 400
pF1KE3 IQDSLVGQRYNEVMATYLLLGYKSSELEGDTITLKPRPSADLTNSSAPSPSHKVQRSVSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IQDSLVGQRYNEVMATYLLLGYKSSELEGDTITLKPRPSADLTNSSAPSPSHKVQRSVSA
370 380 390 400 410 420
410 420 430 440 450 460
pF1KE3 NPKQRRFSDQA-GPAIPTSNSYSKKTQSNNAENKRPEEDRESGRKASSTAKVPASPLPGL
::::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NPKQRRFSDQAAGPAIPTSNSYSKKTQSNNAENKRPEEDRESGRKASSTAKVPASPLPGL
430 440 450 460 470 480
470 480 490 500 510 520
pF1KE3 ERKKTTPTPSTNSVLSTSTNRSRNSPLLERASLGQASIQNGKDSLTMPGSRASTASASAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ERKKTTPTPSTNSVLSTSTNRSRNSPLLERASLGQASIQNGKDSLTMPGSRASTASASAA
490 500 510 520 530 540
530 540 550 560 570 580
pF1KE3 VSAARPRQHQKSMSASVHPNKASGLPPTESNCEVPRPSTAPQRVPVASPSAHNISSSGGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VSAARPRQHQKSMSASVHPNKASGLPPTESNCEVPRPSTAPQRVPVASPSAHNISSSGGA
550 560 570 580 590 600
590 600 610 620 630 640
pF1KE3 PDRTNFPRGVSSRSTFHAGQLRQVRDQQNLPYGVTPASPSGHSQGRRGASGSIFSKFTSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PDRTNFPRGVSSRSTFHAGQLRQVRDQQNLPYGVTPASPSGHSQGRRGASGSIFSKFTSK
610 620 630 640 650 660
650 660 670 680 690 700
pF1KE3 FVRRNLNEPESKDRVETLRPHVVGSGGNDKEKEEFREAKPRSLRFTWSMKTTSSMEPNEM
::::::. .. ::::::::::::::::::::::::::::::::::::::::::
XP_011 FVRRNLSFRFAR------RPHVVGSGGNDKEKEEFREAKPRSLRFTWSMKTTSSMEPNEM
670 680 690 700 710
710 720 730 740 750 760
pF1KE3 MREIRKVLDANSCQSELHEKYMLLCMHGTPGHEDFVQWEMEVCKLPRLSLNGVRFKRISG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MREIRKVLDANSCQSELHEKYMLLCMHGTPGHEDFVQWEMEVCKLPRLSLNGVRFKRISG
720 730 740 750 760 770
770
pF1KE3 TSMAFKNIASKIANELKL
::::::::::::::::::
XP_011 TSMAFKNIASKIANELKL
780 790
>>NP_001034558 (OMIM: 600526) serine/threonine-protein k (788 aa)
initn: 4264 init1: 2716 opt: 4212 Z-score: 1760.3 bits: 336.5 E(85289): 2.6e-91
Smith-Waterman score: 5070; 98.7% identity (98.7% similar) in 788 aa overlap (1-778:1-788)
10 20 30 40 50 60
pF1KE3 MSSARTPLPTLNERDTEQPTLGHLDSKPSSKSNMIRGRNSATSADEQPHIGNYRLLKTIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSSARTPLPTLNERDTEQPTLGHLDSKPSSKSNMIRGRNSATSADEQPHIGNYRLLKTIG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 KGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKLFREVRIMKVLNHPNIVKLFEVIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKLFREVRIMKVLNHPNIVKLFEVIE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 TEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFIVHRDLKAEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFIVHRDLKAEN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 LLLDADMNIKIADFGFSNEFTFGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLLDADMNIKIADFGFSNEFTFGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVIL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 YTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLILNPSKRGTLEQIMK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLILNPSKRGTLEQIMK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 DRWMNVGHEDDELKPYVEPLPDYKDPRRTELMVSMGYTREEIQDSLVGQRYNEVMATYLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DRWMNVGHEDDELKPYVEPLPDYKDPRRTELMVSMGYTREEIQDSLVGQRYNEVMATYLL
310 320 330 340 350 360
370 380 390 400 410
pF1KE3 LGYKSSELEGDTITLKPRPSADLTNSSAPSPSHKVQRSVSANPKQRRFSDQA-GPAIPTS
:::::::::::::::::::::::::::::::::::::::::::::::::::: :::::::
NP_001 LGYKSSELEGDTITLKPRPSADLTNSSAPSPSHKVQRSVSANPKQRRFSDQAAGPAIPTS
370 380 390 400 410 420
420 430 440 450 460 470
pF1KE3 NSYSKKTQSNNAENKRPEEDRESGRKASSTAKVPASPLPGLERKKTTPTPSTNSVLSTST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NSYSKKTQSNNAENKRPEEDRESGRKASSTAKVPASPLPGLERKKTTPTPSTNSVLSTST
430 440 450 460 470 480
480 490 500 510 520 530
pF1KE3 NRSRNSPLLERASLGQASIQNGKDSLTMPGSRASTASASAAVSAARPRQHQKSMSASVHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NRSRNSPLLERASLGQASIQNGKDSLTMPGSRASTASASAAVSAARPRQHQKSMSASVHP
490 500 510 520 530 540
540 550 560 570 580 590
pF1KE3 NKASGLPPTESNCEVPRPSTAPQRVPVASPSAHNISSSGGAPDRTNFPRGVSSRSTFHAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NKASGLPPTESNCEVPRPSTAPQRVPVASPSAHNISSSGGAPDRTNFPRGVSSRSTFHAG
550 560 570 580 590 600
600 610 620 630 640 650
pF1KE3 QLRQVRDQQNLPYGVTPASPSGHSQGRRGASGSIFSKFTSKFVRRNL---------NEPE
::::::::::::::::::::::::::::::::::::::::::::::: ::::
NP_001 QLRQVRDQQNLPYGVTPASPSGHSQGRRGASGSIFSKFTSKFVRRNLSFRFARRNLNEPE
610 620 630 640 650 660
660 670 680 690 700 710
pF1KE3 SKDRVETLRPHVVGSGGNDKEKEEFREAKPRSLRFTWSMKTTSSMEPNEMMREIRKVLDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SKDRVETLRPHVVGSGGNDKEKEEFREAKPRSLRFTWSMKTTSSMEPNEMMREIRKVLDA
670 680 690 700 710 720
720 730 740 750 760 770
pF1KE3 NSCQSELHEKYMLLCMHGTPGHEDFVQWEMEVCKLPRLSLNGVRFKRISGTSMAFKNIAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NSCQSELHEKYMLLCMHGTPGHEDFVQWEMEVCKLPRLSLNGVRFKRISGTSMAFKNIAS
730 740 750 760 770 780
pF1KE3 KIANELKL
::::::::
NP_001 KIANELKL
>>XP_016872799 (OMIM: 600526) PREDICTED: serine/threonin (763 aa)
initn: 4211 init1: 4211 opt: 4211 Z-score: 1760.1 bits: 336.4 E(85289): 2.7e-91
Smith-Waterman score: 4975; 98.1% identity (98.1% similar) in 778 aa overlap (1-778:1-763)
10 20 30 40 50 60
pF1KE3 MSSARTPLPTLNERDTEQPTLGHLDSKPSSKSNMIRGRNSATSADEQPHIGNYRLLKTIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSSARTPLPTLNERDTEQPTLGHLDSKPSSKSNMIRGRNSATSADEQPHIGNYRLLKTIG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 KGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKLFREVRIMKVLNHPNIVKLFEVIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKLFREVRIMKVLNHPNIVKLFEVIE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 TEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFIVHRDLKAEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFIVHRDLKAEN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 LLLDADMNIKIADFGFSNEFTFGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLLDADMNIKIADFGFSNEFTFGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVIL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 YTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLILNPSKRGTLEQIMK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLILNPSKRGTLEQIMK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 DRWMNVGHEDDELKPYVEPLPDYKDPRRTELMVSMGYTREEIQDSLVGQRYNEVMATYLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DRWMNVGHEDDELKPYVEPLPDYKDPRRTELMVSMGYTREEIQDSLVGQRYNEVMATYLL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 LGYKSSELEGDTITLKPRPSADLTNSSAPSPSHKVQRSVSANPKQRRFSDQAGPAIPTSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGYKSSELEGDTITLKPRPSADLTNSSAPSPSHKVQRSVSANPKQRRFSDQAGPAIPTSN
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 SYSKKTQSNNAENKRPEEDRESGRKASSTAKVPASPLPGLERKKTTPTPSTNSVLSTSTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SYSKKTQSNNAENKRPEEDRESGRKASSTAKVPASPLPGLERKKTTPTPSTNSVLSTSTN
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 RSRNSPLLERASLGQASIQNGKDSLTMPGSRASTASASAAVSAARPRQHQKSMSASVHPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RSRNSPLLERASLGQASIQNGKDSLTMPGSRASTASASAAVSAARPRQHQKSMSASVHPN
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 KASGLPPTESNCEVPRPSTAPQRVPVASPSAHNISSSGGAPDRTNFPRGVSSRSTFHAGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KASGLPPTESNCEVPRPSTAPQRVPVASPSAHNISSSGGAPDRTNFPRGVSSRSTFHAGQ
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 LRQVRDQQNLPYGVTPASPSGHSQGRRGASGSIFSKFTSKFVRRNLNEPESKDRVETLRP
:::::::::::::::::::::::::::::::::::::::::::: :
XP_016 LRQVRDQQNLPYGVTPASPSGHSQGRRGASGSIFSKFTSKFVRR---------------P
610 620 630 640
670 680 690 700 710 720
pF1KE3 HVVGSGGNDKEKEEFREAKPRSLRFTWSMKTTSSMEPNEMMREIRKVLDANSCQSELHEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HVVGSGGNDKEKEEFREAKPRSLRFTWSMKTTSSMEPNEMMREIRKVLDANSCQSELHEK
650 660 670 680 690 700
730 740 750 760 770
pF1KE3 YMLLCMHGTPGHEDFVQWEMEVCKLPRLSLNGVRFKRISGTSMAFKNIASKIANELKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YMLLCMHGTPGHEDFVQWEMEVCKLPRLSLNGVRFKRISGTSMAFKNIASKIANELKL
710 720 730 740 750 760
>>XP_011543091 (OMIM: 600526) PREDICTED: serine/threonin (808 aa)
initn: 4149 init1: 2601 opt: 4098 Z-score: 1713.3 bits: 327.9 E(85289): 1.1e-88
Smith-Waterman score: 4956; 97.9% identity (98.2% similar) in 777 aa overlap (12-778:32-808)
10 20 30 40
pF1KE3 MSSARTPLPTLNERDTEQPTLGHLDSKPSSKSNMIRGRNSA
..: :::::::::::::::::::::::
XP_011 EVAGSPFPFLQSVACLLTLAHIPAVGNILQHRRRGAGPTLGHLDSKPSSKSNMIRGRNSA
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE3 TSADEQPHIGNYRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKLFREV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TSADEQPHIGNYRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKLFREV
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE3 RIMKVLNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RIMKVLNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVS
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE3 AVQYCHQKFIVHRDLKAENLLLDADMNIKIADFGFSNEFTFGNKLDTFCGSPPYAAPELF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AVQYCHQKFIVHRDLKAENLLLDADMNIKIADFGFSNEFTFGNKLDTFCGSPPYAAPELF
190 200 210 220 230 240
230 240 250 260 270 280
pF1KE3 QGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLL
250 260 270 280 290 300
290 300 310 320 330 340
pF1KE3 KKFLILNPSKRGTLEQIMKDRWMNVGHEDDELKPYVEPLPDYKDPRRTELMVSMGYTREE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KKFLILNPSKRGTLEQIMKDRWMNVGHEDDELKPYVEPLPDYKDPRRTELMVSMGYTREE
310 320 330 340 350 360
350 360 370 380 390 400
pF1KE3 IQDSLVGQRYNEVMATYLLLGYKSSELEGDTITLKPRPSADLTNSSAPSPSHKVQRSVSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IQDSLVGQRYNEVMATYLLLGYKSSELEGDTITLKPRPSADLTNSSAPSPSHKVQRSVSA
370 380 390 400 410 420
410 420 430 440 450 460
pF1KE3 NPKQRRFSDQA-GPAIPTSNSYSKKTQSNNAENKRPEEDRESGRKASSTAKVPASPLPGL
::::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NPKQRRFSDQAAGPAIPTSNSYSKKTQSNNAENKRPEEDRESGRKASSTAKVPASPLPGL
430 440 450 460 470 480
470 480 490 500 510 520
pF1KE3 ERKKTTPTPSTNSVLSTSTNRSRNSPLLERASLGQASIQNGKDSLTMPGSRASTASASAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ERKKTTPTPSTNSVLSTSTNRSRNSPLLERASLGQASIQNGKDSLTMPGSRASTASASAA
490 500 510 520 530 540
530 540 550 560 570 580
pF1KE3 VSAARPRQHQKSMSASVHPNKASGLPPTESNCEVPRPSTAPQRVPVASPSAHNISSSGGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VSAARPRQHQKSMSASVHPNKASGLPPTESNCEVPRPSTAPQRVPVASPSAHNISSSGGA
550 560 570 580 590 600
590 600 610 620 630 640
pF1KE3 PDRTNFPRGVSSRSTFHAGQLRQVRDQQNLPYGVTPASPSGHSQGRRGASGSIFSKFTSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PDRTNFPRGVSSRSTFHAGQLRQVRDQQNLPYGVTPASPSGHSQGRRGASGSIFSKFTSK
610 620 630 640 650 660
650 660 670 680 690
pF1KE3 FVRRNL---------NEPESKDRVETLRPHVVGSGGNDKEKEEFREAKPRSLRFTWSMKT
:::::: :::::::::::::::::::::::::::::::::::::::::::::
XP_011 FVRRNLSFRFARRNLNEPESKDRVETLRPHVVGSGGNDKEKEEFREAKPRSLRFTWSMKT
670 680 690 700 710 720
700 710 720 730 740 750
pF1KE3 TSSMEPNEMMREIRKVLDANSCQSELHEKYMLLCMHGTPGHEDFVQWEMEVCKLPRLSLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TSSMEPNEMMREIRKVLDANSCQSELHEKYMLLCMHGTPGHEDFVQWEMEVCKLPRLSLN
730 740 750 760 770 780
760 770
pF1KE3 GVRFKRISGTSMAFKNIASKIANELKL
:::::::::::::::::::::::::::
XP_011 GVRFKRISGTSMAFKNIASKIANELKL
790 800
>>XP_011543095 (OMIM: 600526) PREDICTED: serine/threonin (784 aa)
initn: 3434 init1: 2601 opt: 4085 Z-score: 1708.1 bits: 326.9 E(85289): 2.1e-88
Smith-Waterman score: 4849; 97.1% identity (97.4% similar) in 768 aa overlap (12-778:32-784)
10 20 30 40
pF1KE3 MSSARTPLPTLNERDTEQPTLGHLDSKPSSKSNMIRGRNSA
..: :::::::::::::::::::::::
XP_011 EVAGSPFPFLQSVACLLTLAHIPAVGNILQHRRRGAGPTLGHLDSKPSSKSNMIRGRNSA
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE3 TSADEQPHIGNYRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKLFREV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TSADEQPHIGNYRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKLFREV
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE3 RIMKVLNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RIMKVLNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVS
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE3 AVQYCHQKFIVHRDLKAENLLLDADMNIKIADFGFSNEFTFGNKLDTFCGSPPYAAPELF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AVQYCHQKFIVHRDLKAENLLLDADMNIKIADFGFSNEFTFGNKLDTFCGSPPYAAPELF
190 200 210 220 230 240
230 240 250 260 270 280
pF1KE3 QGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLL
250 260 270 280 290 300
290 300 310 320 330 340
pF1KE3 KKFLILNPSKRGTLEQIMKDRWMNVGHEDDELKPYVEPLPDYKDPRRTELMVSMGYTREE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KKFLILNPSKRGTLEQIMKDRWMNVGHEDDELKPYVEPLPDYKDPRRTELMVSMGYTREE
310 320 330 340 350 360
350 360 370 380 390 400
pF1KE3 IQDSLVGQRYNEVMATYLLLGYKSSELEGDTITLKPRPSADLTNSSAPSPSHKVQRSVSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IQDSLVGQRYNEVMATYLLLGYKSSELEGDTITLKPRPSADLTNSSAPSPSHKVQRSVSA
370 380 390 400 410 420
410 420 430 440 450 460
pF1KE3 NPKQRRFSDQA-GPAIPTSNSYSKKTQSNNAENKRPEEDRESGRKASSTAKVPASPLPGL
::::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NPKQRRFSDQAAGPAIPTSNSYSKKTQSNNAENKRPEEDRESGRKASSTAKVPASPLPGL
430 440 450 460 470 480
470 480 490 500 510 520
pF1KE3 ERKKTTPTPSTNSVLSTSTNRSRNSPLLERASLGQASIQNGKDSLTMPGSRASTASASAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ERKKTTPTPSTNSVLSTSTNRSRNSPLLERASLGQASIQNGKDSLTMPGSRASTASASAA
490 500 510 520 530 540
530 540 550 560 570 580
pF1KE3 VSAARPRQHQKSMSASVHPNKASGLPPTESNCEVPRPSTAPQRVPVASPSAHNISSSGGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VSAARPRQHQKSMSASVHPNKASGLPPTESNCEVPRPSTAPQRVPVASPSAHNISSSGGA
550 560 570 580 590 600
590 600 610 620 630 640
pF1KE3 PDRTNFPRGVSSRSTFHAGQLRQVRDQQNLPYGVTPASPSGHSQGRRGASGSIFSKFTSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PDRTNFPRGVSSRSTFHAGQLRQVRDQQNLPYGVTPASPSGHSQGRRGASGSIFSKFTSK
610 620 630 640 650 660
650 660 670 680 690 700
pF1KE3 FVRRNLNEPESKDRVETLRPHVVGSGGNDKEKEEFREAKPRSLRFTWSMKTTSSMEPNEM
::: ::::::::::::::::::::::::::::::::::::::::::
XP_011 FVR---------------RPHVVGSGGNDKEKEEFREAKPRSLRFTWSMKTTSSMEPNEM
670 680 690 700
710 720 730 740 750 760
pF1KE3 MREIRKVLDANSCQSELHEKYMLLCMHGTPGHEDFVQWEMEVCKLPRLSLNGVRFKRISG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MREIRKVLDANSCQSELHEKYMLLCMHGTPGHEDFVQWEMEVCKLPRLSLNGVRFKRISG
710 720 730 740 750 760
770
pF1KE3 TSMAFKNIASKIANELKL
::::::::::::::::::
XP_011 TSMAFKNIASKIANELKL
770 780
>>NP_001156769 (OMIM: 600526) serine/threonine-protein k (709 aa)
initn: 4079 init1: 3282 opt: 3306 Z-score: 1388.4 bits: 267.6 E(85289): 1.3e-70
Smith-Waterman score: 4504; 91.1% identity (91.1% similar) in 778 aa overlap (1-778:1-709)
10 20 30 40 50 60
pF1KE3 MSSARTPLPTLNERDTEQPTLGHLDSKPSSKSNMIRGRNSATSADEQPHIGNYRLLKTIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSSARTPLPTLNERDTEQPTLGHLDSKPSSKSNMIRGRNSATSADEQPHIGNYRLLKTIG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 KGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKLFREVRIMKVLNHPNIVKLFEVIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKLFREVRIMKVLNHPNIVKLFEVIE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 TEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFIVHRDLKAEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFIVHRDLKAEN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 LLLDADMNIKIADFGFSNEFTFGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLLDADMNIKIADFGFSNEFTFGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVIL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 YTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLILNPSKRGTLEQIMK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLILNPSKRGTLEQIMK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 DRWMNVGHEDDELKPYVEPLPDYKDPRRTELMVSMGYTREEIQDSLVGQRYNEVMATYLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DRWMNVGHEDDELKPYVEPLPDYKDPRRTELMVSMGYTREEIQDSLVGQRYNEVMATYLL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 LGYKSSELEGDTITLKPRPSADLTNSSAPSPSHKVQRSVSANPKQRRFSDQAGPAIPTSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LGYKSSELEGDTITLKPRPSADLTNSSAPSPSHKVQRSVSANPKQRRFSDQAGPAIPTSN
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 SYSKKTQSNNAENKRPEEDRESGRKASSTAKVPASPLPGLERKKTTPTPSTNSVLSTSTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SYSKKTQSNNAENKRPEEDRESGRKASSTAKVPASPLPGLERKKTTPTPSTNSVLSTSTN
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 RSRNSPLLERASLGQASIQNGKDSLTMPGSRASTASASAAVSAARPRQHQKSMSASVHPN
::::::::::::::::::::::::
NP_001 RSRNSPLLERASLGQASIQNGKDS------------------------------------
490 500
550 560 570 580 590 600
pF1KE3 KASGLPPTESNCEVPRPSTAPQRVPVASPSAHNISSSGGAPDRTNFPRGVSSRSTFHAGQ
::::::::::::::::::::::::::::::::::::::::::
NP_001 ------------------TAPQRVPVASPSAHNISSSGGAPDRTNFPRGVSSRSTFHAGQ
510 520 530 540
610 620 630 640 650 660
pF1KE3 LRQVRDQQNLPYGVTPASPSGHSQGRRGASGSIFSKFTSKFVRRNLNEPESKDRVETLRP
:::::::::::::::::::::::::::::::::::::::::::: :
NP_001 LRQVRDQQNLPYGVTPASPSGHSQGRRGASGSIFSKFTSKFVRR---------------P
550 560 570 580 590
670 680 690 700 710 720
pF1KE3 HVVGSGGNDKEKEEFREAKPRSLRFTWSMKTTSSMEPNEMMREIRKVLDANSCQSELHEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HVVGSGGNDKEKEEFREAKPRSLRFTWSMKTTSSMEPNEMMREIRKVLDANSCQSELHEK
600 610 620 630 640 650
730 740 750 760 770
pF1KE3 YMLLCMHGTPGHEDFVQWEMEVCKLPRLSLNGVRFKRISGTSMAFKNIASKIANELKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YMLLCMHGTPGHEDFVQWEMEVCKLPRLSLNGVRFKRISGTSMAFKNIASKIANELKL
660 670 680 690 700
>>NP_004945 (OMIM: 600526) serine/threonine-protein kina (724 aa)
initn: 3282 init1: 3282 opt: 3306 Z-score: 1388.3 bits: 267.6 E(85289): 1.4e-70
Smith-Waterman score: 4639; 93.1% identity (93.1% similar) in 778 aa overlap (1-778:1-724)
10 20 30 40 50 60
pF1KE3 MSSARTPLPTLNERDTEQPTLGHLDSKPSSKSNMIRGRNSATSADEQPHIGNYRLLKTIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MSSARTPLPTLNERDTEQPTLGHLDSKPSSKSNMIRGRNSATSADEQPHIGNYRLLKTIG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 KGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKLFREVRIMKVLNHPNIVKLFEVIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 KGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKLFREVRIMKVLNHPNIVKLFEVIE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 TEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFIVHRDLKAEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 TEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFIVHRDLKAEN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 LLLDADMNIKIADFGFSNEFTFGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LLLDADMNIKIADFGFSNEFTFGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVIL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 YTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLILNPSKRGTLEQIMK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 YTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLILNPSKRGTLEQIMK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 DRWMNVGHEDDELKPYVEPLPDYKDPRRTELMVSMGYTREEIQDSLVGQRYNEVMATYLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 DRWMNVGHEDDELKPYVEPLPDYKDPRRTELMVSMGYTREEIQDSLVGQRYNEVMATYLL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 LGYKSSELEGDTITLKPRPSADLTNSSAPSPSHKVQRSVSANPKQRRFSDQAGPAIPTSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LGYKSSELEGDTITLKPRPSADLTNSSAPSPSHKVQRSVSANPKQRRFSDQAGPAIPTSN
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 SYSKKTQSNNAENKRPEEDRESGRKASSTAKVPASPLPGLERKKTTPTPSTNSVLSTSTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 SYSKKTQSNNAENKRPEEDRESGRKASSTAKVPASPLPGLERKKTTPTPSTNSVLSTSTN
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 RSRNSPLLERASLGQASIQNGKDSLTMPGSRASTASASAAVSAARPRQHQKSMSASVHPN
::::::::::::::::::::::::
NP_004 RSRNSPLLERASLGQASIQNGKDS------------------------------------
490 500
550 560 570 580 590 600
pF1KE3 KASGLPPTESNCEVPRPSTAPQRVPVASPSAHNISSSGGAPDRTNFPRGVSSRSTFHAGQ
::::::::::::::::::::::::::::::::::::::::::
NP_004 ------------------TAPQRVPVASPSAHNISSSGGAPDRTNFPRGVSSRSTFHAGQ
510 520 530 540
610 620 630 640 650 660
pF1KE3 LRQVRDQQNLPYGVTPASPSGHSQGRRGASGSIFSKFTSKFVRRNLNEPESKDRVETLRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LRQVRDQQNLPYGVTPASPSGHSQGRRGASGSIFSKFTSKFVRRNLNEPESKDRVETLRP
550 560 570 580 590 600
670 680 690 700 710 720
pF1KE3 HVVGSGGNDKEKEEFREAKPRSLRFTWSMKTTSSMEPNEMMREIRKVLDANSCQSELHEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 HVVGSGGNDKEKEEFREAKPRSLRFTWSMKTTSSMEPNEMMREIRKVLDANSCQSELHEK
610 620 630 640 650 660
730 740 750 760 770
pF1KE3 YMLLCMHGTPGHEDFVQWEMEVCKLPRLSLNGVRFKRISGTSMAFKNIASKIANELKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 YMLLCMHGTPGHEDFVQWEMEVCKLPRLSLNGVRFKRISGTSMAFKNIASKIANELKL
670 680 690 700 710 720
778 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 16:27:10 2016 done: Mon Nov 7 16:27:11 2016
Total Scan time: 11.900 Total Display time: 0.210
Function used was FASTA [36.3.4 Apr, 2011]