Result of FASTA (omim) for
pFN21AE3682
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3682, 417 aa
1>>>pF1KE3682 417 - 417 aa - 417 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.9106+/-0.000307; mu= 8.3470+/- 0.019
mean_var=218.2669+/-44.541, 0's: 0 Z-trim(124.3): 133 B-trim: 821 in 1/57
Lambda= 0.086812
statistics sampled from 45610 (45750) to 45610 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.83), E-opt: 0.2 (0.536), width: 16
Scan time: 11.110
The best scores are: opt bits E(85289)
NP_954586 (OMIM: 611086) forkhead box protein D4-l ( 417) 2977 385.0 1.9e-106
NP_954714 (OMIM: 611085) forkhead box protein D4-l ( 416) 2920 377.8 2.7e-104
NP_997188 (OMIM: 601092) forkhead box protein D4 [ ( 439) 2404 313.2 8e-85
NP_036316 (OMIM: 611084) forkhead box protein D4-l ( 408) 1980 260.1 7.4e-69
NP_004465 (OMIM: 602211) forkhead box protein D2 [ ( 495) 767 108.3 4.5e-23
NP_004463 (OMIM: 601091) forkhead box protein D1 [ ( 465) 756 106.8 1.1e-22
NP_036315 (OMIM: 607836,611539) forkhead box prote ( 478) 685 98.0 5.5e-20
NP_036318 (OMIM: 107250,601094,610256) forkhead bo ( 319) 647 93.0 1.1e-18
NP_004464 (OMIM: 241850,602617,616534) forkhead bo ( 373) 608 88.2 3.7e-17
NP_005241 (OMIM: 603252) forkhead box protein L1 [ ( 345) 544 80.2 9.1e-15
NP_005242 (OMIM: 153400,602402) forkhead box prote ( 501) 538 79.6 2e-14
NP_001444 (OMIM: 601090,601631,602482) forkhead bo ( 553) 532 78.9 3.6e-14
NP_004109 (OMIM: 602939) forkhead box protein S1 [ ( 330) 518 76.9 8.4e-14
NP_075555 (OMIM: 110100,605597,608996) forkhead bo ( 376) 509 75.8 2e-13
NP_001442 (OMIM: 265380,601089) forkhead box prote ( 379) 500 74.7 4.4e-13
NP_004488 (OMIM: 602295) hepatocyte nuclear factor ( 350) 499 74.5 4.6e-13
NP_710141 (OMIM: 600288) hepatocyte nuclear factor ( 457) 484 72.8 2e-12
NP_068556 (OMIM: 600288) hepatocyte nuclear factor ( 463) 484 72.8 2e-12
NP_001443 (OMIM: 603250) forkhead box protein F2 [ ( 444) 480 72.3 2.8e-12
NP_001129121 (OMIM: 612351) forkhead box protein I ( 420) 476 71.7 3.8e-12
XP_016876735 (OMIM: 602294) PREDICTED: hepatocyte ( 439) 469 70.9 7.2e-12
NP_004487 (OMIM: 602294) hepatocyte nuclear factor ( 472) 469 70.9 7.6e-12
NP_150285 (OMIM: 612788) forkhead box protein Q1 [ ( 403) 465 70.3 9.6e-12
NP_036320 (OMIM: 274600,600791,601093) forkhead bo ( 378) 453 68.8 2.6e-11
NP_005240 (OMIM: 164874,613454) forkhead box prote ( 489) 442 67.5 8.1e-11
NP_001445 (OMIM: 602291) forkhead box protein J1 [ ( 421) 403 62.6 2.2e-09
XP_011513493 (OMIM: 616302) PREDICTED: forkhead bo ( 570) 393 61.5 6.3e-09
NP_001032242 (OMIM: 616302) forkhead box protein K ( 733) 393 61.6 7.5e-09
NP_004505 (OMIM: 147685) forkhead box protein K2 [ ( 660) 383 60.3 1.7e-08
XP_005270689 (OMIM: 616035) PREDICTED: forkhead bo ( 630) 349 56.0 3.1e-07
XP_006710522 (OMIM: 616035) PREDICTED: forkhead bo ( 596) 347 55.7 3.5e-07
XP_006710521 (OMIM: 616035) PREDICTED: forkhead bo ( 607) 344 55.4 4.6e-07
NP_001185780 (OMIM: 616035) forkhead box protein J ( 622) 344 55.4 4.7e-07
NP_001185779 (OMIM: 616035) forkhead box protein J ( 622) 344 55.4 4.7e-07
XP_011539328 (OMIM: 616035) PREDICTED: forkhead bo ( 622) 344 55.4 4.7e-07
NP_055762 (OMIM: 616035) forkhead box protein J3 i ( 622) 344 55.4 4.7e-07
XP_016856182 (OMIM: 616035) PREDICTED: forkhead bo ( 573) 342 55.1 5.3e-07
NP_001185781 (OMIM: 616035) forkhead box protein J ( 588) 342 55.1 5.4e-07
XP_016880718 (OMIM: 600838,601705) PREDICTED: fork ( 567) 337 54.5 8.1e-07
XP_011523672 (OMIM: 600838,601705) PREDICTED: fork ( 436) 325 52.8 1.9e-06
XP_011523670 (OMIM: 600838,601705) PREDICTED: fork ( 436) 325 52.8 1.9e-06
XP_011523671 (OMIM: 600838,601705) PREDICTED: fork ( 436) 325 52.8 1.9e-06
XP_011523669 (OMIM: 600838,601705) PREDICTED: fork ( 462) 325 52.9 2e-06
XP_011523664 (OMIM: 600838,601705) PREDICTED: fork ( 648) 325 53.0 2.5e-06
XP_016880717 (OMIM: 600838,601705) PREDICTED: fork ( 648) 325 53.0 2.5e-06
XP_005258103 (OMIM: 600838,601705) PREDICTED: fork ( 648) 325 53.0 2.5e-06
NP_003584 (OMIM: 600838,601705) forkhead box prote ( 648) 325 53.0 2.5e-06
XP_011523661 (OMIM: 600838,601705) PREDICTED: fork ( 649) 325 53.0 2.5e-06
XP_011523660 (OMIM: 600838,601705) PREDICTED: fork ( 649) 325 53.0 2.5e-06
NP_003914 (OMIM: 603621) forkhead box protein H1 [ ( 365) 314 51.4 4.4e-06
>>NP_954586 (OMIM: 611086) forkhead box protein D4-like (417 aa)
initn: 3076 init1: 2977 opt: 2977 Z-score: 2031.9 bits: 385.0 E(85289): 1.9e-106
Smith-Waterman score: 2977; 99.3% identity (99.8% similar) in 417 aa overlap (1-417:1-417)
10 20 30 40 50 60
pF1KE3 MNLPRAERLRSTPQRSLRDSDGEDGKIDVLGEEEDEDEVEDEEEAASQQFLEQSLQPGLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_954 MNLPRAERLRSTPQRSLRDSDGEDGKIDVLGEEEDEDEVEDEEEAASQQFLEQSLQPGLQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 VARWGGVALPREHIEGGGGPSDPSEFGTKFRAPPRSAAASEDARQPAKPPYSYIALITMA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_954 VARWGGVALPREHIEGGGGPSDPSEFGTKFRAPPRSAAASEDARQPAKPPYSYIALITMA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 ILQNPHKRLTLSGICAFISGRFPYYRRKFPAWQNSIRHNLSLNDCFVKIPREPGHPGKGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_954 ILQNPHKRLTLSGICAFISGRFPYYRRKFPAWQNSIRHNLSLNDCFVKIPREPGHPGKGN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 YWSLDPASQDMFDNGSFLRRRKRFKRHQLTPGAHLPHPFPLPAAHAALHNPHPGPLLGAP
:::::::::::::::::::::::::::::::::::::::::::::::::::.::::::::
NP_954 YWSLDPASQDMFDNGSFLRRRKRFKRHQLTPGAHLPHPFPLPAAHAALHNPRPGPLLGAP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 APPQPVPGAYPNTAPGRRPYALLHPHPLRYLLLSAPVYAGAPKKAEGAALATPAPFPCCS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_954 APPQPVPGAYPNTAPGRRPYALLHPHPLRYLLLSAPVYAGAPKKAEGAALATPAPFPCCS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 PHLVLSLGRRARVWRRHREADASLSALRVLCKGSGERVQGLRRVCPRPRGATATCSSDHQ
:::::::::::::::::::::::::::::::::::::::::::.::::::::::::::::
NP_954 PHLVLSLGRRARVWRRHREADASLSALRVLCKGSGERVQGLRRICPRPRGATATCSSDHQ
310 320 330 340 350 360
370 380 390 400 410
pF1KE3 ACCIPRPLPLCCKCPPPPLLGQFCSNSSSIRRRTAPTAALPPRARCWAGTCRPRRRC
::::::::::::::::::::::::::::::::::::::::::::::::::::::: :
NP_954 ACCIPRPLPLCCKCPPPPLLGQFCSNSSSIRRRTAPTAALPPRARCWAGTCRPRRPC
370 380 390 400 410
>>NP_954714 (OMIM: 611085) forkhead box protein D4-like (416 aa)
initn: 2749 init1: 2749 opt: 2920 Z-score: 1993.4 bits: 377.8 E(85289): 2.7e-104
Smith-Waterman score: 2920; 98.1% identity (98.3% similar) in 417 aa overlap (1-417:1-416)
10 20 30 40 50 60
pF1KE3 MNLPRAERLRSTPQRSLRDSDGEDGKIDVLGEEEDEDEVEDEEEAASQQFLEQSLQPGLQ
:::::::: ::::::::::::::::::::::::::::::::::: : :::::::::::::
NP_954 MNLPRAERPRSTPQRSLRDSDGEDGKIDVLGEEEDEDEVEDEEEEARQQFLEQSLQPGLQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 VARWGGVALPREHIEGGGGPSDPSEFGTKFRAPPRSAAASEDARQPAKPPYSYIALITMA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_954 VARWGGVALPREHIEGGGGPSDPSEFGTKFRAPPRSAAASEDARQPAKPPYSYIALITMA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 ILQNPHKRLTLSGICAFISGRFPYYRRKFPAWQNSIRHNLSLNDCFVKIPREPGHPGKGN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_954 ILQNPHKRLTLSGICAFISGRFPYYRRKFPAWQNSIRHNLSLNDCFVKIPREPGHPGKGN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 YWSLDPASQDMFDNGSFLRRRKRFKRHQLTPGAHLPHPFPLPAAHAALHNPHPGPLLGAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_954 YWSLDPASQDMFDNGSFLRRRKRFKRHQLTPGAHLPHPFPLPAAHAALHNPHPGPLLGAP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 APPQPVPGAYPNTAPGRRPYALLHPHPLRYLLLSAPVYAGAPKKAEGAALATPAPFPCCS
::::::::::::::::::::::::::::::::::: :::::::::::: :::::::::::
NP_954 APPQPVPGAYPNTAPGRRPYALLHPHPLRYLLLSARVYAGAPKKAEGADLATPAPFPCCS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 PHLVLSLGRRARVWRRHREADASLSALRVLCKGSGERVQGLRRVCPRPRGATATCSSDHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_954 PHLVLSLGRRARVWRRHREADASLSALRVLCKGSGERVQGLRRVCPRPRGATATCSSDHQ
310 320 330 340 350 360
370 380 390 400 410
pF1KE3 ACCIPRPLPLCCKCPPPPLLGQFCSNSSSIRRRTAPTAALPPRARCWAGTCRPRRRC
:::::.::::::::::: :::::::::::::: ::::::::::::::::::::::::
NP_954 ACCIPKPLPLCCKCPPPLLLGQFCSNSSSIRR-TAPTAALPPRARCWAGTCRPRRRC
370 380 390 400 410
>>NP_997188 (OMIM: 601092) forkhead box protein D4 [Homo (439 aa)
initn: 2201 init1: 2201 opt: 2404 Z-score: 1643.8 bits: 313.2 E(85289): 8e-85
Smith-Waterman score: 2406; 87.4% identity (90.3% similar) in 404 aa overlap (1-395:1-400)
10 20 30 40 50 60
pF1KE3 MNLPRAERLRSTPQRSLRDSDGEDGKIDVLGEEEDEDEVEDEEEAASQQFLEQSLQPGLQ
:::::::::::::::::::::::::::::::::::::: ::::::::::::::::::
NP_997 MNLPRAERLRSTPQRSLRDSDGEDGKIDVLGEEEDEDE----EEAASQQFLEQSLQPGLQ
10 20 30 40 50
70 80 90 100 110 120
pF1KE3 VARWGGVALPREHIEGGGGPSDPSEFGTKFRAPPRSAAASEDARQPAKPPYSYIALITMA
::::::::::::::::::::::::::::.::::::::::::::::::::: :::::::::
NP_997 VARWGGVALPREHIEGGGGPSDPSEFGTEFRAPPRSAAASEDARQPAKPPSSYIALITMA
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE3 ILQNPHKRLTLSGICAFISGRFPYYRRKFPAWQNSIRHNLSLNDCFVKIPREPGHPGKGN
:::.::::::::::::::: ::::::::::::::::::::::::::::::::::.:::::
NP_997 ILQSPHKRLTLSGICAFISDRFPYYRRKFPAWQNSIRHNLSLNDCFVKIPREPGRPGKGN
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE3 YWSLDPASQDMFDNGSFLRRRKRFKRHQLTPGAHLPHPFPLPAAHAALHNPHPGPLLGAP
::::::::::::::::::::::::.::: ::::::::::::::::::::::.::::::::
NP_997 YWSLDPASQDMFDNGSFLRRRKRFQRHQPTPGAHLPHPFPLPAAHAALHNPRPGPLLGAP
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE3 APPQPVPGAYPNTAPGRRPYALLHPHPLRYLLLSAPVYAGAPKKAEGAALATPAPFPCCS
:::::::::::::.::::::::::::: ::::::::.::::::::::: :::::::::::
NP_997 APPQPVPGAYPNTGPGRRPYALLHPHPPRYLLLSAPAYAGAPKKAEGADLATPAPFPCCS
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE3 PHLVLSLGRRARVWRRHREADASLSALRVLCKGSGERVQGLRRVCPRPRGATATCSSDHQ
::::::::::::::::::::::::::::: ::::::::::::::::::::::: ::::.:
NP_997 PHLVLSLGRRARVWRRHREADASLSALRVSCKGSGERVQGLRRVCPRPRGATAPCSSDRQ
300 310 320 330 340 350
370 380 390 400 410
pF1KE3 ACCI-----PRPLPLCCK--CPPPP--LLGQFCSNSSSIRRRTAPTAALPPRARCWAGTC
:: : : : : .:: : .:.. : :
NP_997 ACRTILQQQQRHQEEDCANGCAPTKGAVLGGHLSAASALLRYQAVAEGSGLTSLAAPLGG
360 370 380 390 400 410
pF1KE3 RPRRRC
NP_997 EGTSPVFLVSPTPSSLAESAGPS
420 430
>>NP_036316 (OMIM: 611084) forkhead box protein D4-like (408 aa)
initn: 2039 init1: 1515 opt: 1980 Z-score: 1357.2 bits: 260.1 E(85289): 7.4e-69
Smith-Waterman score: 1980; 93.7% identity (96.7% similar) in 303 aa overlap (1-303:1-302)
10 20 30 40 50 60
pF1KE3 MNLPRAERLRSTPQRSLRDSDGEDGKIDVLGEEEDEDEVEDEEEAASQQFLEQSLQPGLQ
:::::::: ::::::::::::::::::::::::::::::::::: :::.:::::::::::
NP_036 MNLPRAERPRSTPQRSLRDSDGEDGKIDVLGEEEDEDEVEDEEEEASQKFLEQSLQPGLQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 VARWGGVALPREHIEGGGGPSDPSEFGTKFRAPPRSAAASEDARQPAKPPYSYIALITMA
:::::::::::::::::: :::::::::.:::::::::::::::::::::::::::::::
NP_036 VARWGGVALPREHIEGGG-PSDPSEFGTEFRAPPRSAAASEDARQPAKPPYSYIALITMA
70 80 90 100 110
130 140 150 160 170 180
pF1KE3 ILQNPHKRLTLSGICAFISGRFPYYRRKFPAWQNSIRHNLSLNDCFVKIPREPGHPGKGN
:::.:::::::::::::::::::::::::::::::::::::::::::::::::::::::.
NP_036 ILQSPHKRLTLSGICAFISGRFPYYRRKFPAWQNSIRHNLSLNDCFVKIPREPGHPGKGT
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE3 YWSLDPASQDMFDNGSFLRRRKRFKRHQLTPGAHLPHPFPLPAAHAALHNPHPGPLLGAP
:::::::::::::::::::::::::::::::::::::::::::::::::::.::::::::
NP_036 YWSLDPASQDMFDNGSFLRRRKRFKRHQLTPGAHLPHPFPLPAAHAALHNPRPGPLLGAP
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE3 APPQPVPGAYPNTAPGRRPYALLHPHPLRYLLLSAPVYAGAPKKAEGAALATPAPFPCCS
: ::::::::::::::::::::::::: ::::::::.::::::::::: ::::. .: .
NP_036 ALPQPVPGAYPNTAPGRRPYALLHPHPPRYLLLSAPAYAGAPKKAEGADLATPGTLPVLQ
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE3 PHLVLSLGRRARVWRRHREADASLSALRVLCKGSGERVQGLRRVCPRPRGATATCSSDHQ
: :
NP_036 PSLGPQPWEEGKGLASPPGGGCISFSIESIMQGVRGAGTGAAQSLSPTAWSYCPLLQRPS
300 310 320 330 340 350
>>NP_004465 (OMIM: 602211) forkhead box protein D2 [Homo (495 aa)
initn: 772 init1: 695 opt: 767 Z-score: 535.1 bits: 108.3 E(85289): 4.5e-23
Smith-Waterman score: 783; 51.3% identity (65.2% similar) in 279 aa overlap (32-297:61-322)
10 20 30 40 50 60
pF1KE3 NLPRAERLRSTPQRSLRDSDGEDGKIDVLGEEEDEDEVEDEEEAASQQFLEQSLQPGLQV
:: . : .:::::... . : . .
NP_004 GGGSGGGELPARSGPRAPRDVLPHGHEPPAEEAEADLAEDEEESGGCSDGEPRALASRGA
40 50 60 70 80 90
70 80 90 100 110
pF1KE3 ARWGGVALP-REHIEGGGGPSDPSEFGTKFRAPPRSAAASEDARQP-AKPPYSYIALITM
: .: : .:..::. :. :: ..::. :.: .::::::::::::
NP_004 AAAAGSPGPGAAAARGAAGPG-PG--------PPSGGAAT---RSPLVKPPYSYIALITM
100 110 120 130
120 130 140 150 160 170
pF1KE3 AILQNPHKRLTLSGICAFISGRFPYYRRKFPAWQNSIRHNLSLNDCFVKIPREPGHPGKG
::::.:.:::::: :: ::::::::::.:::::::::::::::::::::::::::.::::
NP_004 AILQSPKKRLTLSEICEFISGRFPYYREKFPAWQNSIRHNLSLNDCFVKIPREPGNPGKG
140 150 160 170 180 190
180 190 200 210 220 230
pF1KE3 NYWSLDPASQDMFDNGSFLRRRKRFKRHQLTPGAHLPHPFP---LPAAHAALHNPH---P
:::.::: : :::::::::::::::::. : : ::: : : .. :: .: :
NP_004 NYWTLDPESADMFDNGSFLRRRKRFKRQPLPPPHPHPHPHPELLLRGGAAAAGDPGAFLP
200 210 220 230 240 250
240 250 260 270 280
pF1KE3 G-PLLGAPAPPQ----PVPGAYPNTAPGRRPYALLHPHPLRYLLLSAPVYAGAPKKAEGA
: :: . :. :: : :: :. :::: . . .: . : .. .
NP_004 GFAAYGAYGYGYGLALPAYGAPP---PGPAPHP--HPHPHAFAFAAAAAAAPCQLSVPPG
260 270 280 290 300 310
290 300 310 320 330 340
pF1KE3 ALATPAPFPCCSPHLVLSLGRRARVWRRHREADASLSALRVLCKGSGERVQGLRRVCPRP
:.: : :
NP_004 RAAAPPPGPPTASVFAGAGSAPAPAPASGSGPGPGPAGLPAFLGAELGCAKAFYAASLSP
320 330 340 350 360 370
>>NP_004463 (OMIM: 601091) forkhead box protein D1 [Homo (465 aa)
initn: 760 init1: 660 opt: 756 Z-score: 528.0 bits: 106.8 E(85289): 1.1e-22
Smith-Waterman score: 791; 42.1% identity (58.7% similar) in 404 aa overlap (14-400:53-422)
10 20 30 40
pF1KE3 MNLPRAERLRSTPQRSLRDSDGEDGKIDVLGEEEDEDEVEDEE
.: :. ::: ... : ::::.:..
NP_004 GEGEDEEDEEEEDDDEGGGGGPRLAVPAQRRRRRRSYAGED-ELEDLEEEEDDDDILLAP
30 40 50 60 70 80
50 60 70 80 90 100
pF1KE3 EAASQQFLEQSLQPGLQVARWGGVALPREHIEGGGGPSDPSEFGTKFRAPPRSAAASEDA
:... :: : .:.. :::: . . :. :. :
NP_004 PAGGSP-----APPGPAPAAGAGAG-------GGGGGGGAGGGGS----------AGSGA
90 100 110
110 120 130 140 150 160
pF1KE3 RQP-AKPPYSYIALITMAILQNPHKRLTLSGICAFISGRFPYYRRKFPAWQNSIRHNLSL
..: .::::::::::::::::.:.:::::: :: ::::::::::.:::::::::::::::
NP_004 KNPLVKPPYSYIALITMAILQSPKKRLTLSEICEFISGRFPYYREKFPAWQNSIRHNLSL
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE3 NDCFVKIPREPGHPGKGNYWSLDPASQDMFDNGSFLRRRKRFKRHQLTP-GAHLPHPFPL
::::::::::::.:::::::.::: : :::::::::::::::::. : : .: . . :
NP_004 NDCFVKIPREPGNPGKGNYWTLDPESADMFDNGSFLRRRKRFKRQPLLPPNAAAAESLLL
180 190 200 210 220 230
230 240 250 260 270
pF1KE3 PAAHAA--LHNPHPGPLLGAPAPPQPVPGAYPNTAPGRRPYALLHPHPLRYLLLSAPVYA
.: :: .: . : :::: : : :: : ::. . : . ..:
NP_004 RGAGAAGGAGDPAAAAALFPPAPPPP-PHAY-----GYGPYGCGYGLQLPPYAPPSALFA
240 250 260 270 280 290
280 290 300 310 320 330
pF1KE3 GAPKKAEGAALATPAPFPCCSPHLVLS-LGRRARVWRRHREADASLSALRV-LCKGSGER
.: : .::. .: : :: . . :.: : .: : . : . : . :..:
NP_004 AAAAAAAAAAFHPHSPPPPPPPHGAAAELARTAFGYRPHPLGAALPGPLPASAAKAGGPG
300 310 320 330 340 350
340 350 360 370 380
pF1KE3 VQGLRR-------VCPRPRGATATCSSDHQACCI----PRPLPLCCKCPPPPLLGQFCSN
...: : . : .:. .. :: : : :. : : : :.
NP_004 ASALARSPFSIESIIGGSLGPAAAAAAAAQAAAAAQASPSPSPVAAP-PAPGSSGGGCAA
360 370 380 390 400 410
390 400 410
pF1KE3 SSSIRRRTAPTAALPPRARCWAGTCRPRRRC
.... .:.:::
NP_004 QAAV----GPAAALTRSLVAAAAAAASSVSSSAALGTLHQGTALSSVENFTARISNC
420 430 440 450 460
>>NP_036315 (OMIM: 607836,611539) forkhead box protein D (478 aa)
initn: 733 init1: 666 opt: 685 Z-score: 479.8 bits: 98.0 E(85289): 5.5e-20
Smith-Waterman score: 700; 48.5% identity (60.5% similar) in 299 aa overlap (18-303:38-314)
10 20 30 40
pF1KE3 MNLPRAERLRSTPQRSLRDSD-GED---GKIDVLGEEEDEDEVEDEE
.::: : : : .. .: :: .
NP_036 SASDMSGQTVLTAEDVDIDVVGEGDDGLEEKDSDAGCDSPAGPPELRLDEADEVPPAAPH
10 20 30 40 50 60
50 60 70 80 90
pF1KE3 EAASQQFLEQSLQ-P----GLQVARWGGVALPR-EHIEGGGGPSDPSEFGTKFRAPPRSA
.. : .: : : : .. : :. :. . .:: : . . : : ::
NP_036 HGQPQPPHQQPLTLPKEAAGAGAGPGGDVGAPEADGCKGGVGGEEGGASGGGPGAGSGSA
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE3 ---AASEDARQPAKPPYSYIALITMAILQNPHKRLTLSGICAFISGRFPYYRRKFPAWQN
: :. . .::::::::::::::::.:.:.::::::: :::.::::::.:::::::
NP_036 GGLAPSKPKNSLVKPPYSYIALITMAILQSPQKKLTLSGICEFISNRFPYYREKFPAWQN
130 140 150 160 170 180
160 170 180 190 200 210
pF1KE3 SIRHNLSLNDCFVKIPREPGHPGKGNYWSLDPASQDMFDNGSFLRRRKRFKRHQLTPGAH
::::::::::::::::::::.:::::::.::: :.::::::::::::::::::: :
NP_036 SIRHNLSLNDCFVKIPREPGNPGKGNYWTLDPQSEDMFDNGSFLRRRKRFKRHQQE---H
190 200 210 220 230 240
220 230 240 250 260 270
pF1KE3 LPHPFPLPAAHAALHNPHPGPLLGAPAPPQPVPGAYPNTAPGRRPYALLHPHPLRYLLLS
: ..:: : : : :: ..: :::.: :: :
NP_036 L-------REQTALMMQSFGAYSLAAAA-----GA---AGPYGRPYGL-HPAAAAGAY-S
250 260 270 280
280 290 300 310 320 330
pF1KE3 APVYAGAPKKAEGAALATPAPFPCCSPHLVLSLGRRARVWRRHREADASLSALRVLCKGS
: :.: : .::: : .: .: :
NP_036 HP--AAAAAAAAAAALQYPYALPPVAPVLPPAVPLLPSGELGRKAAAFGSQLGPGLQLQL
290 300 310 320 330 340
>>NP_036318 (OMIM: 107250,601094,610256) forkhead box pr (319 aa)
initn: 592 init1: 552 opt: 647 Z-score: 456.3 bits: 93.0 E(85289): 1.1e-18
Smith-Waterman score: 647; 48.8% identity (62.3% similar) in 252 aa overlap (57-300:17-254)
30 40 50 60 70 80
pF1KE3 IDVLGEEEDEDEVEDEEEAASQQFLEQSLQPGLQ-VARWGGVALPREHIEGGGGPSDPSE
:.: :: : : : : : . .
NP_036 MAGRSDMDPPAAFSGFPALPAVAPSGPPPSPLAGAEPGREPEEAAA
10 20 30 40
90 100 110 120 130 140
pF1KE3 FGTKFRAPPRSAAASEDARQP---AKPPYSYIALITMAILQNPHKRLTLSGICAFISGRF
: :: . . .. :.: .::::::::::.::. . : .::::..: ::. ::
NP_036 -GRGEAAPTPAPGPGRRRRRPLQRGKPPYSYIALIAMALAHAPGRRLTLAAIYRFITERF
50 60 70 80 90 100
150 160 170 180 190 200
pF1KE3 PYYRRKFPAWQNSIRHNLSLNDCFVKIPREPGHPGKGNYWSLDPASQDMFDNGSFLRRRK
.:: . :::::::::.:::::::.:::::.:::::::.::::. :::::::::::::
NP_036 AFYRDSPRKWQNSIRHNLTLNDCFVKVPREPGNPGKGNYWTLDPAAADMFDNGSFLRRRK
110 120 130 140 150 160
210 220 230 240 250 260
pF1KE3 RFKRHQLTP-GAHLPHPFPLPAAHAALHNPHPGPLLGAPAPPQPVPGAYPNTAPGRRPYA
:::: .: .: : : ::: .: . : ::: : .: ::. :: : :.:
NP_036 RFKRAELPAHAAAAPGP-PLPFPYAP-YAPAPGPALLVP-PPSAGPGPSP---PAR----
170 180 190 200 210
270 280 290 300 310
pF1KE3 LLHPHPLRYLLLSAPVYAG--APKKAEGAAL-ATPAPFPCCSPHLVLSLGRRARVWRRHR
:. : : : :: ::. :: :. : :: :.
NP_036 LFSVDSLVNL---QPELAGLGAPEPPCCAAPDAAAAAFPPCAAAASPPLYSQVPDRLVLP
220 230 240 250 260 270
320 330 340 350 360 370
pF1KE3 EADASLSALRVLCKGSGERVQGLRRVCPRPRGATATCSSDHQACCIPRPLPLCCKCPPPP
NP_036 ATRPGPGPLPAEPLLALAGPAAALGPLSPGEAYLRQPGFASGLERYL
280 290 300 310
>>NP_004464 (OMIM: 241850,602617,616534) forkhead box pr (373 aa)
initn: 566 init1: 544 opt: 608 Z-score: 429.0 bits: 88.2 E(85289): 3.7e-17
Smith-Waterman score: 608; 49.3% identity (67.0% similar) in 215 aa overlap (87-295:30-240)
60 70 80 90 100 110
pF1KE3 PGLQVARWGGVALPREHIEGGGGPSDPSEFGTKFRAPPRSAAASEDAR--QPAKPPYSYI
:. .: :.:.. . : : .:::::::
NP_004 MTAESGPPPPQPEVLATVKEERGETAAGAGVPGEATGRGAGGRRRKRPLQRGKPPYSYI
10 20 30 40 50
120 130 140 150 160 170
pF1KE3 ALITMAILQNPHKRLTLSGICAFISGRFPYYRRKFPAWQNSIRHNLSLNDCFVKIPREPG
:::.::: . :..::::.:: ::. :::.:: . :::::::::.:::::.::::: :
NP_004 ALIAMAIAHAPERRLTLGGIYKFITERFPFYRDNPKKWQNSIRHNLTLNDCFLKIPREAG
60 70 80 90 100 110
180 190 200 210 220 230
pF1KE3 HPGKGNYWSLDPASQDMFDNGSFLRRRKRFKRHQLTPGAHLPHPFPLPAAHAALHNPHPG
.:::::::.::: ..:::..:::::::::::: .:. : :: :: .
NP_004 RPGKGNYWALDPNAEDMFESGSFLRRRKRFKRSDLSTYPAYMHDAAAAAAAAAAAAAAAA
120 130 140 150 160 170
240 250 260 270 280 290
pF1KE3 PLLGA-PAPPQPVPGAYPNTAPGRRPYALLHPHPLRYLLLS-AP--VYAGAPKKAEGAAL
. :: :: : ::: . : : .: : :. : : .: :.. .:.. . :
NP_004 IFPGAVPAARPPYPGA---VYAGYAPPSLAAPPPVYYPAASPGPCRVFGLVPERPLSPEL
180 190 200 210 220 230
300 310 320 330 340 350
pF1KE3 ATPAPFPCCSPHLVLSLGRRARVWRRHREADASLSALRVLCKGSGERVQGLRRVCPRPRG
. :::
NP_004 G-PAPSGPGGSCAFASAGAPATTTGYQPAGCTGARPANPSAYAAAYAGPDGAYPQGAGSA
240 250 260 270 280 290
>>NP_005241 (OMIM: 603252) forkhead box protein L1 [Homo (345 aa)
initn: 574 init1: 507 opt: 544 Z-score: 386.1 bits: 80.2 E(85289): 9.1e-15
Smith-Waterman score: 553; 45.5% identity (62.6% similar) in 211 aa overlap (68-256:14-219)
40 50 60 70 80 90
pF1KE3 EVEDEEEAASQQFLEQSLQPGLQVARWGGVALPREHIEGGGGPSDPSEFGTKFRAPPRSA
: : .. : :. : : :: .
NP_005 MSHLFDPRLPALAASPMLYLYGPERPGLPLAF-----APAAAL
10 20 30
100 110 120 130 140 150
pF1KE3 AASEDARQPAKPPYSYIALITMAILQNPHKRLTLSGICAFISGRFPYYRRKFPAWQNSIR
::: :. : ::::::::::.::: . :..:.::.:: :: :::.:. . .::::::
NP_005 AASGRAETPQKPPYSYIALIAMAIQDAPEQRVTLNGIYQFIMDRFPFYHDNRQGWQNSIR
40 50 60 70 80 90
160 170 180 190 200 210
pF1KE3 HNLSLNDCFVKIPREPGHPGKGNYWSLDPASQDMFDNGSFLRRRKRFKRHQLTPGAHLPH
:::::::::::.::: :.::::.::.::: :::.::.. ::... : .: :. :.
NP_005 HNLSLNDCFVKVPREKGRPGKGSYWTLDPRCLDMFENGNYRRRKRKPKPGPGAPEAKRPR
100 110 120 130 140 150
220 230 240 250
pF1KE3 PF---------PLPAAHAALHNPH----------PGPLLGAPAPPQPV--PG-AYPNTAP
: .. :. .: :.::: .:.:: :. :: : ::
NP_005 AETHQRSAEAQPEAGSGAGGSGPAISRLQAAPAGPSPLLDGPSPPAPLHWPGTASPNEDA
160 170 180 190 200 210
260 270 280 290 300 310
pF1KE3 GRRPYALLHPHPLRYLLLSAPVYAGAPKKAEGAALATPAPFPCCSPHLVLSLGRRARVWR
:
NP_005 GDAAQGAAAVAVGQAARTGDGPGSPLRPASRSSPKSSDKSKSFSIDSILAGKQGQKPPSG
220 230 240 250 260 270
417 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 10:53:54 2016 done: Sun Nov 6 10:53:55 2016
Total Scan time: 11.110 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]