FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE3677, 268 aa
  1>>>pF1KE3677 268 - 268 aa - 268 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 7.9767+/-0.000273; mu= 5.6989+/- 0.017
 mean_var=200.8772+/-39.417, 0's: 0 Z-trim(125.8): 24  B-trim: 0 in 0/60
 Lambda= 0.090492
 statistics sampled from 50217 (50250) to 50217 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.855), E-opt: 0.2 (0.589), width:  16
 Scan time:  7.870

The best scores are:                                      opt bits E(85289)
NP_061140 (OMIM: 608689) mesoderm posterior protei ( 268) 1889 257.8 1.5e-68
NP_001035047 (OMIM: 277300,605195,608681) mesoderm ( 397)  702 103.0 9.2e-22
NP_001099039 (OMIM: 612209) mesogenin-1 [Homo sapi ( 193)  241 42.5 0.00071


>>NP_061140 (OMIM: 608689) mesoderm posterior protein 1   (268 aa)
 initn: 1889 init1: 1889 opt: 1889  Z-score: 1351.4  bits: 257.8 E(85289): 1.5e-68
Smith-Waterman score: 1889; 100.0% identity (100.0% similar) in 268 aa overlap (1-268:1-268)

               10        20        30        40        50        60
pF1KE3 MAQPLCPPLSESWMLSAAWGPTRRPPPSDKDCGRSLVSSPDSWGSTPADSPVASPARPGT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 MAQPLCPPLSESWMLSAAWGPTRRPPPSDKDCGRSLVSSPDSWGSTPADSPVASPARPGT
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE3 LRDPRAPSVGRRGARSSRLGSGQRQSASEREKLRMRTLARALHELRRFLPPSVAPAGQSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 LRDPRAPSVGRRGARSSRLGSGQRQSASEREKLRMRTLARALHELRRFLPPSVAPAGQSL
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE3 TKIETLRLAIRYIGHLSAVLGLSEESLQRRCRQRGDAGSPRGCPLCPDDCPAQMQTRTQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 TKIETLRLAIRYIGHLSAVLGLSEESLQRRCRQRGDAGSPRGCPLCPDDCPAQMQTRTQA
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE3 EGQGQGRGLGLVSAVRAGASWGSPPACPGARAAPEPRDPPALFAEAACPEGQAMEPSPPS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 EGQGQGRGLGLVSAVRAGASWGSPPACPGARAAPEPRDPPALFAEAACPEGQAMEPSPPS
              190       200       210       220       230       240

              250       260        
pF1KE3 PLLPGDVLALLETWMPLSPLEWLPEEPK
       ::::::::::::::::::::::::::::
NP_061 PLLPGDVLALLETWMPLSPLEWLPEEPK
              250       260        

>>NP_001035047 (OMIM: 277300,605195,608681) mesoderm pos  (397 aa)
 initn: 720 init1: 620 opt: 702  Z-score: 511.7  bits: 103.0 E(85289): 9.2e-22
Smith-Waterman score: 794; 52.1% identity (62.7% similar) in 303 aa overlap (1-268:1-286)

                10            20        30        40        50     
pF1KE3 MAQ-PLCPPLS----ESWMLSAAWGPTRRPPPSDKDCGRSLVSSPDSWGSTPADSP--VA
       ::: :  :: :    . :... .:: .     .  : . : .:: :: :: : :.   . 
NP_001 MAQSP--PPQSLLGHDHWIFAQGWGWA-----GHWD-STSPASSSDSSGSCPCDGARGLP
                 10        20              30        40        50  

             60        70        80        90       100       110  
pF1KE3 SPARPG-TLRDPRAPSVGRRGARSSRLGSGQRQSASEREKLRMRTLARALHELRRFLPPS
       .:  :. . :  .: ..  : ::..  : :::::::::::::::::::::::::::::::
NP_001 QPQPPSCSSRAAEAAATTPRRARTGPAG-GQRQSASEREKLRMRTLARALHELRRFLPPS
             60        70        80         90       100       110 

            120       130       140       150       160       170  
pF1KE3 VAPAGQSLTKIETLRLAIRYIGHLSAVLGLSEESLQRRCRQRGDAGSPRGCPLCPDDCPA
       .::::::::::::::::::::::::::::::::::: : ::::::::: :::::::  ::
NP_001 LAPAGQSLTKIETLRLAIRYIGHLSAVLGLSEESLQCRRRQRGDAGSPWGCPLCPDRGPA
             120       130       140       150       160       170 

            180       190                           200       210  
pF1KE3 QMQTRTQAEGQGQGRGLG--------------------LVSAVRAGASWGSPPACPGARA
       . ::.....:::::.: :                    ::::: : :::::: :::::.:
NP_001 EAQTQAEGQGQGQGQGQGQGQGQGQGQGQGQGQGRRPGLVSAVLAEASWGSPSACPGAQA
             180       190       200       210       220       230 

                   220       230       240       250       260     
pF1KE3 APE-------PRDPPALFAEAACPEGQAMEPSPPSPLLPGDVLALLETWMPLSPLEWLPE
       :::         :: :  .   ::. :    :::         : :  : : .   :   
NP_001 APERLGRGVHDTDPWA--TPPYCPKIQ----SPPYSSQGTTSDASL--WTPPQGCPWTQS
             240         250           260       270         280   

                                                                   
pF1KE3 EPK                                                         
        :.                                                         
NP_001 SPEPRNPPVPWTAAPATLELAAVYQGLSVSPEPCLSLGAPSLLPHPSCQRLQPQTPGRCW
           290       300       310       320       330       340   

>>NP_001099039 (OMIM: 612209) mesogenin-1 [Homo sapiens]  (193 aa)
 initn: 261 init1: 220 opt: 241  Z-score: 190.5  bits: 42.5 E(85289): 0.00071
Smith-Waterman score: 241; 47.2% identity (76.4% similar) in 89 aa overlap (57-145:101-187)

         30        40        50        60        70        80      
pF1KE3 PSDKDCGRSLVSSPDSWGSTPADSPVASPARPGTLRDPRAPSVGRRGARSSRLGSGQRQS
                                     .:  :.   .:.. ..:..  :..  .:..
NP_001 HGGASSGGSEGCSVGGASGLVEVDYNMLAFQPTHLQGGGGPKA-QKGTKV-RMSVQRRRK
               80        90       100       110         120        

         90       100       110       120       130       140      
pF1KE3 ASEREKLRMRTLARALHELRRFLPPSVAPAGQSLTKIETLRLAIRYIGHLSAVLGLSEES
       ::::::::::::: ::: :: .:::  .  :: ::::.::. .:.:::.:. .:. ..: 
NP_001 ASEREKLRMRTLADALHTLRNYLPPVYSQRGQPLTKIQTLKYTIKYIGELTDLLNRGREP
      130       140       150       160       170       180        

        150       160       170       180       190       200      
pF1KE3 LQRRCRQRGDAGSPRGCPLCPDDCPAQMQTRTQAEGQGQGRGLGLVSAVRAGASWGSPPA
                                                                   
NP_001 RAQSA                                                       
      190                                                          




268 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sun Nov  6 14:10:01 2016 done: Sun Nov  6 14:10:02 2016
 Total Scan time:  7.870 Total Display time: -0.010

Function used was FASTA [36.3.4 Apr, 2011]