Result of FASTA (ccds) for
pFN21AE3674
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3674, 399 aa
1>>>pF1KE3674 399 - 399 aa - 399 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.3392+/-0.000931; mu= 16.1872+/- 0.056
mean_var=59.2739+/-11.958, 0's: 0 Z-trim(104.9): 12 B-trim: 56 in 1/49
Lambda= 0.166588
statistics sampled from 8120 (8125) to 8120 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.628), E-opt: 0.2 (0.25), width: 16
Scan time: 2.680
The best scores are: opt bits E(32554)
CCDS2392.1 LANCL1 gene_id:10314|Hs108|chr2 ( 399) 2767 673.5 9e-194
CCDS5517.1 LANCL2 gene_id:55915|Hs108|chr7 ( 450) 1590 390.7 1.4e-108
CCDS55398.1 LANCL3 gene_id:347404|Hs108|chrX ( 420) 688 173.9 2.4e-43
CCDS14240.1 LANCL3 gene_id:347404|Hs108|chrX ( 388) 560 143.1 4.1e-34
>>CCDS2392.1 LANCL1 gene_id:10314|Hs108|chr2 (399 aa)
initn: 2767 init1: 2767 opt: 2767 Z-score: 3592.3 bits: 673.5 E(32554): 9e-194
Smith-Waterman score: 2767; 100.0% identity (100.0% similar) in 399 aa overlap (1-399:1-399)
10 20 30 40 50 60
pF1KE3 MAQRAFPNPYADYNKSLAEGYFDAAGRLTPEFSQRLTNKIRELLQQMERGLKSADPRDGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS23 MAQRAFPNPYADYNKSLAEGYFDAAGRLTPEFSQRLTNKIRELLQQMERGLKSADPRDGT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 GYTGWAGIAVLYLHLYDVFGDPAYLQLAHGYVKQSLNCLTKRSITFLCGDAGPLAVAAVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS23 GYTGWAGIAVLYLHLYDVFGDPAYLQLAHGYVKQSLNCLTKRSITFLCGDAGPLAVAAVL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 YHKMNNEKQAEDCITRLIHLNKIDPHAPNEMLYGRIGYIYALLFVNKNFGVEKIPQSHIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS23 YHKMNNEKQAEDCITRLIHLNKIDPHAPNEMLYGRIGYIYALLFVNKNFGVEKIPQSHIQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 QICETILTSGENLARKRNFTAKSPLMYEWYQEYYVGAAHGLAGIYYYLMQPSLQVSQGKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS23 QICETILTSGENLARKRNFTAKSPLMYEWYQEYYVGAAHGLAGIYYYLMQPSLQVSQGKL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 HSLVKPSVDYVCQLKFPSGNYPPCIGDNRDLLVHWCHGAPGVIYMLIQAYKVFREEKYLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS23 HSLVKPSVDYVCQLKFPSGNYPPCIGDNRDLLVHWCHGAPGVIYMLIQAYKVFREEKYLC
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 DAYQCADVIWQYGLLKKGYGLCHGSAGNAYAFLTLYNLTQDMKYLYRACKFAEWCLEYGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS23 DAYQCADVIWQYGLLKKGYGLCHGSAGNAYAFLTLYNLTQDMKYLYRACKFAEWCLEYGE
310 320 330 340 350 360
370 380 390
pF1KE3 HGCRTPDTPFSLFEGMAGTIYFLADLLVPTKARFPAFEL
:::::::::::::::::::::::::::::::::::::::
CCDS23 HGCRTPDTPFSLFEGMAGTIYFLADLLVPTKARFPAFEL
370 380 390
>>CCDS5517.1 LANCL2 gene_id:55915|Hs108|chr7 (450 aa)
initn: 1618 init1: 1176 opt: 1590 Z-score: 2062.6 bits: 390.7 E(32554): 1.4e-108
Smith-Waterman score: 1600; 54.2% identity (77.7% similar) in 426 aa overlap (1-399:19-444)
10 20
pF1KE3 MAQRAFPNPYADYNKS----LAEGY-----------------
: .::: ::. ::. . :: :
CCDS55 MGETMSKRLKLHLGGEAEMEERAFVNPFPDYEAAAGALLASGAAEETGCVRPPATTDEPG
10 20 30 40 50 60
30 40 50 60 70
pF1KE3 --FDAAGRLTPEFSQRLTNKIRELLQQMERGLKSADPRDGTGYTGWAGIAVLYLHLYDVF
: :.. .: .:. .::..::::::.:::.:::.: ..::::.:::.:::.:: :
CCDS55 LPFHQDGKIIHNFIRRIQTKIKDLLQQMEEGLKTADPHDCSAYTGWTGIALLYLQLYRVT
70 80 90 100 110 120
80 90 100 110 120 130
pF1KE3 GDPAYLQLAHGYVKQSLNCLTKRSITFLCGDAGPLAVAAVLYHKMNNEKQAEDCITRLIH
: .:: . :::..: :. : .::::::::::::.::.:::. .. ....:.:.:..
CCDS55 CDQTYLLRSLDYVKRTLRNLNGRRVTFLCGDAGPLAVGAVIYHKLRSDCESQECVTKLLQ
130 140 150 160 170 180
140 150 160 170 180 190
pF1KE3 LNKI----DPHAPNEMLYGRIGYIYALLFVNKNFGVEKIPQSHIQQICETILTSGENLAR
:.. . :.:.:::: ::.::::..: ..: . .: :... ..:. ::..:.:
CCDS55 LQRSVVCQESDLPDELLYGRAGYLYALLYLNTEIGPGTVCESAIKEVVNAIIESGKTLSR
190 200 210 220 230 240
200 210 220 230 240 250
pF1KE3 KRNFTAKSPLMYEWYQEYYVGAAHGLAGIYYYLMQPSLQVSQGKLHSLVKPSVDYVCQLK
.. : . ::.:.:... :::::::.:::::.::::. .:.: : .::::.::: . :
CCDS55 EERKTERCPLLYQWHRKQYVGAAHGMAGIYYMLMQPAAKVDQETLTEMVKPSIDYVRHKK
250 260 270 280 290 300
260 270 280 290 300 310
pF1KE3 FPSGNYPPCIGDNRDLLVHWCHGAPGVIYMLIQAYKVFREEKYLCDAYQCADVIWQYGLL
: ::::: .... : ::::::::::::.::.::::::.::::: .:..:.::::: :::
CCDS55 FRSGNYPSSLSNETDRLVHWCHGAPGVIHMLMQAYKVFKEEKYLKEAMECSDVIWQRGLL
310 320 330 340 350 360
320 330 340 350 360 370
pF1KE3 KKGYGLCHGSAGNAYAFLTLYNLTQDMKYLYRACKFAEWCLEYGEHGCRTPDTPFSLFEG
.::::.:::.:::.:.::.:: :::: ::::::::::::::.:: :::: :: :.:::::
CCDS55 RKGYGICHGTAGNGYSFLSLYRLTQDKKYLYRACKFAEWCLDYGAHGCRIPDRPYSLFEG
370 380 390 400 410 420
380 390
pF1KE3 MAGTIYFLADLLVPTKARFPAFEL
:::.:.::.:.: : .:::::::
CCDS55 MAGAIHFLSDVLGPETSRFPAFELDSSKRD
430 440 450
>>CCDS55398.1 LANCL3 gene_id:347404|Hs108|chrX (420 aa)
initn: 721 init1: 349 opt: 688 Z-score: 891.5 bits: 173.9 E(32554): 2.4e-43
Smith-Waterman score: 730; 34.5% identity (61.0% similar) in 423 aa overlap (3-397:4-416)
10 20 30 40 50
pF1KE3 MAQRAFPNPYADYNKSLAEGYFD-AAGRLTPEFSQRLTNKIRELLQQME-RGLKS-ADP
.: : : . ::. :: : . :.. :. .:. ... : : :: . :.
CCDS55 MDTKRCFANRFDDYQGSLLAGQCEEAVAPLVTATIERILQELPPLGGGAEARGATAGASA
10 20 30 40 50 60
60 70 80 90 100
pF1KE3 RDGTGYTGWAGIAVLYLHLYDVFGDPAYLQLAHGYVKQSLN----CLTKRS---------
.: : : ::.: . :: : .: . . :.... : .
CCDS55 CQGGLYGGVAGVAYM---LYHVSQSPLFATARERYLRSAKRLIDACARAEEWGEPDADTR
70 80 90 100 110
110 120 130 140 150
pF1KE3 ITFLCGDAGPLAVAAVLYHKMNNEKQAEDCITRLIHLNKIDPHAP--------NEMLYGR
.:: : :: :::...:: .. .. . .. : . :: .:.. ::
CCDS55 AAFLLGGAGVYAVATLVYHALGRSDYVQP-LGKFRALCAV--CAPVSFLECGSDELFVGR
120 130 140 150 160 170
160 170 180 190 200 210
pF1KE3 IGYIYALLFVNKNFGVEKIPQSHIQQICETILTSGENLARKRNFTAKSPLMYEWYQEYYV
::. : : ...... : . ..:..::..:: ::.. : :. :::: .: :.
CCDS55 AGYLCAALVLKQKLAQEVLTPAQIKSICQAILDSGKQYAIKK--RKPFPLMYSYYGTEYL
180 190 200 210 220 230
220 230 240 250 260 270
pF1KE3 GAAHGLAGIYYYLMQPSLQVSQGKLHSLVKPSVDYVCQLKFPSGNYPPCIGDN---RDLL
::::::..: .:.. ... . . :: :::.. . . . :.:: .:.. .. :
CCDS55 GAAHGLSSILQMLLSYHEHLKPSD-RELVWQSVDFLME-QEQNCNWPPELGETIERENEL
240 250 260 270 280 290
280 290 300 310 320 330
pF1KE3 VHWCHGAPGVIYMLIQAYKVFREEKYLCDAYQCADVIWQYGLLKKGYGLCHGSAGNAYAF
:::::::::. :.. .:: : .. .:: .:... :: :::::: :.::: ::.::.:
CCDS55 VHWCHGAPGIAYLFAKAYLVSKKPQYLDTCIRCGELTWQKGLLKKGPGICHGVAGSAYVF
300 310 320 330 340 350
340 350 360 370 380 390
pF1KE3 LTLYNLTQDMKYLYRACKFAEWCL-EYGEHGCRTPDTPFSLFEGMAGTIYFLADLLVPTK
: :: :: . ::.::: .::.. . : . : :. .. .::.::..::. :: ::: :..
CCDS55 LLLYRLTGNSKYIYRAQRFAQFLFTEEFKAGSRVLESIYSLYEGFSGTVCFLIDLLQPNQ
360 370 380 390 400 410
pF1KE3 ARFPAFEL
:.:: :
CCDS55 AEFPLFSVFV
420
>>CCDS14240.1 LANCL3 gene_id:347404|Hs108|chrX (388 aa)
initn: 552 init1: 333 opt: 560 Z-score: 725.8 bits: 143.1 E(32554): 4.1e-34
Smith-Waterman score: 602; 33.5% identity (59.2% similar) in 373 aa overlap (3-348:4-366)
10 20 30 40 50
pF1KE3 MAQRAFPNPYADYNKSLAEGYFD-AAGRLTPEFSQRLTNKIRELLQQME-RGLKS-ADP
.: : : . ::. :: : . :.. :. .:. ... : : :: . :.
CCDS14 MDTKRCFANRFDDYQGSLLAGQCEEAVAPLVTATIERILQELPPLGGGAEARGATAGASA
10 20 30 40 50 60
60 70 80 90 100
pF1KE3 RDGTGYTGWAGIAVLYLHLYDVFGDPAYLQLAHGYVKQSLN----CLTKRS---------
.: : : ::.: . :: : .: . . :.... : .
CCDS14 CQGGLYGGVAGVAYM---LYHVSQSPLFATARERYLRSAKRLIDACARAEEWGEPDADTR
70 80 90 100 110
110 120 130 140 150
pF1KE3 ITFLCGDAGPLAVAAVLYHKMNNEKQAEDCITRLIHLNKIDPHAP--------NEMLYGR
.:: : :: :::...:: .. .. . .. : . :: .:.. ::
CCDS14 AAFLLGGAGVYAVATLVYHALGRSDYVQP-LGKFRALCAV--CAPVSFLECGSDELFVGR
120 130 140 150 160 170
160 170 180 190 200 210
pF1KE3 IGYIYALLFVNKNFGVEKIPQSHIQQICETILTSGENLARKRNFTAKSPLMYEWYQEYYV
::. : : ...... : . ..:..::..:: ::.. : :. :::: .: :.
CCDS14 AGYLCAALVLKQKLAQEVLTPAQIKSICQAILDSGKQYAIKKR--KPFPLMYSYYGTEYL
180 190 200 210 220 230
220 230 240 250 260 270
pF1KE3 GAAHGLAGIYYYLMQPSLQVSQGKLHSLVKPSVDYVCQLKFPSGNYPPCIGDN---RDLL
::::::..: .:.. ... . . :: :::.. . . . :.:: .:.. .. :
CCDS14 GAAHGLSSILQMLLSYHEHLKPSD-RELVWQSVDFLMEQE-QNCNWPPELGETIERENEL
240 250 260 270 280 290
280 290 300 310 320 330
pF1KE3 VHWCHGAPGVIYMLIQAYKVFREEKYLCDAYQCADVIWQYGLLKKGYGLCHGSAGNAYAF
:::::::::. :.. .:: : .. .:: .:... :: :::::: :.::: ::.::.:
CCDS14 VHWCHGAPGIAYLFAKAYLVSKKPQYLDTCIRCGELTWQKGLLKKGPGICHGVAGSAYVF
300 310 320 330 340 350
340 350 360 370 380 390
pF1KE3 LTLYNLTQDMKYLYRACKFAEWCLEYGEHGCRTPDTPFSLFEGMAGTIYFLADLLVPTKA
: :: :: . ::.:::
CCDS14 LLLYRLTGNSKYIYRAQSSFPVNLIKMEHLLYTRQHCF
360 370 380
399 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 22:32:22 2016 done: Sun Nov 6 22:32:23 2016
Total Scan time: 2.680 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]