Result of FASTA (ccds) for
pFN21AE3670
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3670, 493 aa
1>>>pF1KE3670 493 - 493 aa - 493 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.3399+/-0.000942; mu= 10.1158+/- 0.057
mean_var=146.8961+/-29.956, 0's: 0 Z-trim(110.5): 35 B-trim: 41 in 1/50
Lambda= 0.105820
statistics sampled from 11646 (11674) to 11646 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.707), E-opt: 0.2 (0.359), width: 16
Scan time: 3.280
The best scores are: opt bits E(32554)
CCDS2780.1 ARIH2 gene_id:10425|Hs108|chr3 ( 493) 3509 547.4 1.3e-155
CCDS10244.1 ARIH1 gene_id:25820|Hs108|chr15 ( 557) 1135 185.0 1.8e-46
CCDS4890.1 CUL9 gene_id:23113|Hs108|chr6 (2517) 588 102.0 7.9e-21
CCDS1657.1 RNF144A gene_id:9781|Hs108|chr2 ( 292) 380 69.6 5.4e-12
CCDS34345.1 RNF144B gene_id:255488|Hs108|chr6 ( 303) 379 69.4 6.2e-12
>>CCDS2780.1 ARIH2 gene_id:10425|Hs108|chr3 (493 aa)
initn: 3509 init1: 3509 opt: 3509 Z-score: 2907.3 bits: 547.4 E(32554): 1.3e-155
Smith-Waterman score: 3509; 100.0% identity (100.0% similar) in 493 aa overlap (1-493:1-493)
10 20 30 40 50 60
pF1KE3 MSVDMNSQGSDSNEEDYDPNCEEEEEEEEDDPGDIEDYYVGVASDVEQQGADAFDPEEYQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS27 MSVDMNSQGSDSNEEDYDPNCEEEEEEEEDDPGDIEDYYVGVASDVEQQGADAFDPEEYQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 FTCLTYKESEGALNEHMTSLASVLKVSHSVAKLILVNFHWQVSEILDRYKSNSAQLLVEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS27 FTCLTYKESEGALNEHMTSLASVLKVSHSVAKLILVNFHWQVSEILDRYKSNSAQLLVEA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 RVQPNPSKHVPTSHPPHHCAVCMQFVRKENLLSLACQHQFCRSCWEQHCSVLVKDGVGVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS27 RVQPNPSKHVPTSHPPHHCAVCMQFVRKENLLSLACQHQFCRSCWEQHCSVLVKDGVGVG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 VSCMAQDCPLRTPEDFVFPLLPNEELREKYRRYLFRDYVESHYQLQLCPGADCPMVIRVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS27 VSCMAQDCPLRTPEDFVFPLLPNEELREKYRRYLFRDYVESHYQLQLCPGADCPMVIRVQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 EPRARRVQCNRCNEVFCFKCRQMYHAPTDCATIRKWLTKCADDSETANYISAHTKDCPKC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS27 EPRARRVQCNRCNEVFCFKCRQMYHAPTDCATIRKWLTKCADDSETANYISAHTKDCPKC
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 NICIEKNGGCNHMQCSKCKHDFCWMCLGDWKTHGSEYYECSRYKENPDIVNQSQQAQARE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS27 NICIEKNGGCNHMQCSKCKHDFCWMCLGDWKTHGSEYYECSRYKENPDIVNQSQQAQARE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 ALKKYLFYFERWENHNKSLQLEAQTYQRIHEKIQERVMNNLGTWIDWQYLQNAAKLLAKC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS27 ALKKYLFYFERWENHNKSLQLEAQTYQRIHEKIQERVMNNLGTWIDWQYLQNAAKLLAKC
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 RYTLQYTYPYAYYMESGPRKKLFEYQQAQLEAEIENLSWKVERADSYDRGDLENQMHIAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS27 RYTLQYTYPYAYYMESGPRKKLFEYQQAQLEAEIENLSWKVERADSYDRGDLENQMHIAE
430 440 450 460 470 480
490
pF1KE3 QRRRTLLKDFHDT
:::::::::::::
CCDS27 QRRRTLLKDFHDT
490
>>CCDS10244.1 ARIH1 gene_id:25820|Hs108|chr15 (557 aa)
initn: 950 init1: 319 opt: 1135 Z-score: 947.8 bits: 185.0 E(32554): 1.8e-46
Smith-Waterman score: 1135; 35.4% identity (68.8% similar) in 452 aa overlap (57-492:97-545)
30 40 50 60 70 80
pF1KE3 EEEDDPGDIEDYYVGVASDVEQQGADAFDPEEYQFTCLTYKESEGALNEHMTSLASVLKV
:.:.. :: .. . : . . :..
CCDS10 GGGGGSALGPGGGGGGGGGGGGGGPGHEQEEDYRYEVLTAEQILQHMVECIREVNEVIQN
70 80 90 100 110 120
90 100 110 120 130
pF1KE3 SHSVAKLILVNFHWQVSEILDRY-KSNSAQLLVEARVQPNPSKHVPT-------SHPPHH
......: .:.:. ....:: .: .:..: .: ::::. : :
CCDS10 PATITRILLSHFNWDKEKLMERYFDGNLEKLFAECHVI-NPSKKSRTRQMNTRSSAQDMP
130 140 150 160 170 180
140 150 160 170 180 190
pF1KE3 CAVCMQFVRKENLLSLACQHQFCRSCWEQHCSV-LVKDGVGVGVSCMAQDCPLRTPEDFV
: .:. . . .: : :.:: .:: .. .. ....:.: .:: :. : . . .. :
CCDS10 CQICYLNYPNSYFTGLECGHKFCMQCWSEYLTTKIMEEGMGQTISCPAHGCDILVDDNTV
190 200 210 220 230 240
200 210 220 230 240 250
pF1KE3 FPLLPNEELREKYRRYLFRDYVESHYQLQLCPGADCPMVIRVQEPRARRVQCNRCNEVFC
. :. . ... ::.. . ..:: . :. ::. :: :..:: : :. :.: .:.. ::
CCDS10 MRLITDSKVKLKYQHLITNSFVECNRLLKWCPAPDCHHVVKVQYPDAKPVRC-KCGRQFC
250 260 270 280 290 300
260 270 280 290 300 310
pF1KE3 FKCRQMYHAPTDCATIRKWLTKCADDSETANYISAHTKDCPKCNICIEKNGGCNHMQC--
:.: . .: :. : ..::. :: :::::.:.:.:.::.::::.. :::.:::::: :
CCDS10 FNCGENWHDPVKCKWLKKWIKKCDDDSETSNWIAANTKECPKCHVTIEKDGGCNHMVCRN
310 320 330 340 350 360
320 330 340 350 360 370
pF1KE3 SKCKHDFCWMCLGDWKTHGSEYYECSRYKENPDIVNQSQQAQAREALKKYLFYFERWENH
..:: .:::.::: :. ::: .:.:.::.:. . .. : ..: ::..:::: .:. ::
CCDS10 QNCKAEFCWVCLGPWEPHGSAWYNCNRYNEDDAKAARDAQERSRAALQRYLFYCNRYMNH
370 380 390 400 410 420
380 390 400 410 420 430
pF1KE3 NKSLQLEAQTYQRIHEKIQERVMNNLGTWIDWQYLQNAAKLLAKCRYTLQYTYPYAYYME
.::..: . : ....:..: ..:. .::. :.:..:. .: .:: ::.::: .:.:..
CCDS10 MQSLRFEHKLYAQVKQKMEEMQQHNM-SWIEVQFLKKAVDVLCQCRATLMYTYVFAFYLK
430 440 450 460 470 480
440 450 460 470 480 490
pF1KE3 SGPRKKLFEYQQAQLEAEIENLSWKVERADSYD-----RGDLENQMHIAEQRRRTLLKDF
.. .. .:: .::.:: : :: .:: : : . ...... :.:::.::.
CCDS10 KNNQSIIFENNQADLENATEVLSGYLERDISQDSLQDIKQKVQDKYRYCESRRRVLLQHV
490 500 510 520 530 540
pF1KE3 HDT
:.
CCDS10 HEGYEKDLWEYIED
550
>>CCDS4890.1 CUL9 gene_id:23113|Hs108|chr6 (2517 aa)
initn: 646 init1: 238 opt: 588 Z-score: 487.4 bits: 102.0 E(32554): 7.9e-21
Smith-Waterman score: 634; 27.2% identity (58.8% similar) in 427 aa overlap (64-478:1997-2399)
40 50 60 70 80 90
pF1KE3 DIEDYYVGVASDVEQQGADAFDPEEYQFTCLTYKESEGALNEHMTSLASVLKVSHSVAKL
.. .: :: ... . .. .:.. .::.
CCDS48 PFCGSQSETSKPSPEAVATLASLQLPAGRTMSPQEVEGLMKQTVRQVQETLNLEPDVAQH
1970 1980 1990 2000 2010 2020
100 110 120 130 140 150
pF1KE3 ILVNFHWQVSEILDRYKSNSAQLLVEARVQPNPSKHVPTSHPPHHCAVCMQFVR-KENLL
.:.. :: . ..:. :. . ::. : . . .. ::. : :: ::.. . ..:
CCDS48 LLAHSHWGAEQLLQSYSEDPEPLLLAAGLCVHQAQAVPVR--PDHCPVCVSPLGCDDDLP
2030 2040 2050 2060 2070 2080
160 170 180 190 200 210
pF1KE3 SLACQHQFCRSCWEQHCSVLVKDGVGVGVSCMAQDCPLRTPEDFVFPLLPNEELREKYRR
:: :.: :.:::... .. ..... .. .: ::: . :. .. . :. ::..
CCDS48 SLCCMHYCCKSCWNEYLTTRIEQNLVLNCTCPIADCPAQPTGAFIRAIVSSPEVISKYEK
2090 2100 2110 2120 2130 2140
220 230 240 250 260 270
pF1KE3 YLFRDYVESHYQLQLCPGAD-CPMVIRVQEPRARRVQCNRCNEVFCFKCR-QMYHAPTDC
:.: :::: .: : . . : .. .. . . :..:. . ::.: : :..:
CCDS48 ALLRGYVESCSNLTWCTNPQGCDRIL-CRQGLGCGTTCSKCGWASCFNCSFPEAHYPASC
2150 2160 2170 2180 2190 2200
280 290 300 310 320
pF1KE3 ATIRKWLTKCAD-DSETANYISAH-----TKDCPKCNICIEKNGGCNHMQCSKCKHDFCW
. . .:. . :. ... : : .: ::.:. :::: :: :: :.::.: :::
CCDS48 GHMSQWVDDGGYYDGMSVEAQSKHLAKLISKRCPSCQAPIEKNEGCLHMTCAKCNHGFCW
2210 2220 2230 2240 2250 2260
330 340 350 360 370 380
pF1KE3 MCLGDWKTHGSEYYECSRYKENPDIVNQSQQAQAREALKKYLFYFERWENHNKSLQLEAQ
:: .:: . ..::.:: .:... ::. :.. : :: :... .. ..
CCDS48 RCLKSWKPNHKDYYNCSA------MVSKA----ARQE-KRFQDYNERCTFHHQAREFAVN
2270 2280 2290 2300 2310
390 400 410 420 430 440
pF1KE3 TYQR---IHEKIQERVMNNLGTWIDWQYLQNAAKLLAKCRYTLQYTYPYAYYMESGPRKK
.: ::: : .. .:..: . : . : .: :. :..: ...
CCDS48 LRNRVSAIHEVPPPR---------SFTFLNDACQGLEQARKVLAYACVYSFYSQDAEYMD
2320 2330 2340 2350 2360
450 460 470 480 490
pF1KE3 LFEYQQAQLEAEIENLSWKVERADSYDRGDLENQMHIAEQRRRTLLKDFHDT
. : : .:: . . :. .:.. : :: .....
CCDS48 VVEQQTENLELHTNALQILLEETLLRCR-DLASSLRLLRADCLSTGMELLRRIQERLLAI
2370 2380 2390 2400 2410 2420
CCDS48 LQHSAQDFRVGLQSPSVEAWEAKGPNMPGSQPQASSGPEAEEEEEDDEDDVPEWQQDEFD
2430 2440 2450 2460 2470 2480
>>CCDS1657.1 RNF144A gene_id:9781|Hs108|chr2 (292 aa)
initn: 339 init1: 184 opt: 380 Z-score: 328.8 bits: 69.6 E(32554): 5.4e-12
Smith-Waterman score: 380; 28.9% identity (53.7% similar) in 201 aa overlap (135-327:16-215)
110 120 130 140 150 160
pF1KE3 ILDRYKSNSAQLLVEARVQPNPSKHVPTSHPPHHCAVCMQFVRKENLLSLA-CQHQFCRS
: : .:. :.. ..: :: ::
CCDS16 MTTTRYRPTWDLALDPLVSCKLCLGEYPVEQMTTIAQCQCIFCTL
10 20 30 40
170 180 190 200 210 220
pF1KE3 CWEQHCSVLVKDGVGVGVSCMAQDCPLRTP-EDFVFPLLPNEELREKYRRYLFRDYVESH
: .:. .:.:.:. ...:: :: . .. . . :. ..:.. :. :
CCDS16 CLKQYVELLIKEGLETAISCPDAACPKQGHLQENEIECMVAAEIMQRYKKLQFEREVLFD
50 60 70 80 90 100
230 240 250 260 270
pF1KE3 YQLQLCPGADCPMVIRVQE---PRARRVQCNRCNEVFCFKCRQMYHAPTDCATIRKWLTK
::.. : : ..:. . :::. : :: :. .: : .:
CCDS16 PCRTWCPASTCQAVCQLQDVGLQTPQPVQCKACRMEFCSTCKASWHPGQGCPETMP-ITF
110 120 130 140 150 160
280 290 300 310 320 330
pF1KE3 CADDSETANYI---SAHTKDCPKCNICIEKNGGCNHMQCSKCKHDFCWMCLGDWKTHGSE
.. .: . .: : ::::.. ::.. :: .:.:..::: :::.::
CCDS16 LPGETSAAFKMEEDDAPIKRCPKCKVYIERDEGCAQMMCKNCKHAFCWYCLESLDDDFLL
170 180 190 200 210 220
340 350 360 370 380 390
pF1KE3 YYECSRYKENPDIVNQSQQAQAREALKKYLFYFERWENHNKSLQLEAQTYQRIHEKIQER
CCDS16 IHYDKGPCRNKLGHSRASVIWHRTQVVGIFAGFGLLLLVASPFLLLATPFVLCCKCKCSK
230 240 250 260 270 280
>>CCDS34345.1 RNF144B gene_id:255488|Hs108|chr6 (303 aa)
initn: 329 init1: 217 opt: 379 Z-score: 327.8 bits: 69.4 E(32554): 6.2e-12
Smith-Waterman score: 379; 29.0% identity (54.3% similar) in 210 aa overlap (124-327:17-223)
100 110 120 130 140 150
pF1KE3 ILVNFHWQVSEILDRYKSNSAQLLVEARVQPNPSKHVPTSHPPHHCAVCMQFVRKENLLS
:.:. .:. : : .:. ... .
CCDS34 MGSAGRLHYLAMTAENPTPGDLAPA--PLITCKLCLCEQSLDKMTT
10 20 30 40
160 170 180 190 200 210
pF1KE3 LA-CQHQFCRSCWEQHCSVLVKDGVGVGVSCMAQDC--PLRTPEDFVFPLLPNEELREKY
: :: :: .: .:. .. ...: : ..: . : : . :.: ... . :
CCDS34 LQECQCIFCTACLKQYMQLAIREGCGSPITCPDMVCLNHGTLQEAEIACLVPVDQF-QLY
50 60 70 80 90 100
220 230 240 250 260
pF1KE3 RRYLFRDYVESHYQLQLCPGADCPMVIRV--QEP-RARRVQCNRCNEVFCFKCRQMYHAP
.: :. :. :: ::: : : ..: . :.: :. :: :.. .::
CCDS34 QRLKFEREVHLDPYRTWCPVADCQTVCPVASSDPGQPVLVECPSCHLKFCSCCKDAWHAE
110 120 130 140 150 160
270 280 290 300 310 320
pF1KE3 TDCATIRKWLTKCADDSETANYISAHTKDCPKCNICIEKNGGCNHMQCSKCKHDFCWMCL
..: . . . .. : :.:: : . ::.: :: .:.:..::: :::.::
CCDS34 VSCRDSQPIVLPTEHRALFGTDAEAPIKQCPVCRVYIERNEGCAQMMCKNCKHTFCWYCL
170 180 190 200 210 220
330 340 350 360 370 380
pF1KE3 GDWKTHGSEYYECSRYKENPDIVNQSQQAQAREALKKYLFYFERWENHNKSLQLEAQTYQ
CCDS34 QNLDNDIFLRHYDKGPCRNKLGHSRASVMWNRTQVVGILVGLGIIALVTSPLLLLASPCI
230 240 250 260 270 280
493 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 23:36:06 2016 done: Sun Nov 6 23:36:07 2016
Total Scan time: 3.280 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]