Result of FASTA (omim) for
pFN21AE3663
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3663, 196 aa
1>>>pF1KE3663 196 - 196 aa - 196 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.8064+/-0.000262; mu= 7.2287+/- 0.016
mean_var=111.0539+/-22.256, 0's: 0 Z-trim(123.2): 16 B-trim: 78 in 1/56
Lambda= 0.121705
statistics sampled from 42450 (42468) to 42450 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.825), E-opt: 0.2 (0.498), width: 16
Scan time: 6.000
The best scores are: opt bits E(85289)
NP_055180 (OMIM: 158590,608014,608673) heat shock ( 196) 1382 252.1 4.1e-67
NP_001531 (OMIM: 602195,606595,608634) heat shock ( 205) 395 78.9 6.3e-15
NP_001317308 (OMIM: 123590,608810,613763,613869,61 ( 108) 243 52.0 4e-07
NP_001876 (OMIM: 123590,608810,613763,613869,61518 ( 175) 245 52.5 4.7e-07
NP_001276737 (OMIM: 123590,608810,613763,613869,61 ( 175) 245 52.5 4.7e-07
NP_001276736 (OMIM: 123590,608810,613763,613869,61 ( 175) 245 52.5 4.7e-07
XP_011540910 (OMIM: 123590,608810,613763,613869,61 ( 175) 245 52.5 4.7e-07
NP_653218 (OMIM: 610695) heat shock protein beta-6 ( 160) 238 51.2 1e-06
XP_005261150 (OMIM: 123580,604219) PREDICTED: alph ( 136) 215 47.2 1.5e-05
NP_000385 (OMIM: 123580,604219) alpha-crystallin A ( 173) 215 47.2 1.8e-05
NP_001532 (OMIM: 602179) heat shock protein beta-2 ( 182) 206 45.6 5.5e-05
XP_011539551 (OMIM: 610692) PREDICTED: heat shock ( 263) 184 41.9 0.0011
NP_055239 (OMIM: 610692) heat shock protein beta-7 ( 170) 180 41.1 0.0012
XP_011539552 (OMIM: 610692) PREDICTED: heat shock ( 262) 181 41.3 0.0016
NP_006299 (OMIM: 604624,613376) heat shock protein ( 150) 173 39.8 0.0026
>>NP_055180 (OMIM: 158590,608014,608673) heat shock prot (196 aa)
initn: 1382 init1: 1382 opt: 1382 Z-score: 1325.9 bits: 252.1 E(85289): 4.1e-67
Smith-Waterman score: 1382; 100.0% identity (100.0% similar) in 196 aa overlap (1-196:1-196)
10 20 30 40 50 60
pF1KE3 MADGQMPFSCHYPSRLRRDPFRDSPLSSRLLDDGFGMDPFPDDLTASWPDWALPRLSSAW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MADGQMPFSCHYPSRLRRDPFRDSPLSSRLLDDGFGMDPFPDDLTASWPDWALPRLSSAW
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 PGTLRSGMVPRGPTATARFGVPAEGRTPPPFPGEPWKVCVNVHSFKPEELMVKTKDGYVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 PGTLRSGMVPRGPTATARFGVPAEGRTPPPFPGEPWKVCVNVHSFKPEELMVKTKDGYVE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 VSGKHEEKQQEGGIVSKNFTKKIQLPAEVDPVTVFASLSPEGLLIIEAPQVPPYSTFGES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 VSGKHEEKQQEGGIVSKNFTKKIQLPAEVDPVTVFASLSPEGLLIIEAPQVPPYSTFGES
130 140 150 160 170 180
190
pF1KE3 SFNNELPQDSQEVTCT
::::::::::::::::
NP_055 SFNNELPQDSQEVTCT
190
>>NP_001531 (OMIM: 602195,606595,608634) heat shock prot (205 aa)
initn: 441 init1: 303 opt: 395 Z-score: 389.0 bits: 78.9 E(85289): 6.3e-15
Smith-Waterman score: 405; 39.6% identity (62.0% similar) in 187 aa overlap (1-176:1-174)
10 20 30 40 50
pF1KE3 MADGQMPFSC-HYPSRLRRDPFRDSPLSSRLLDDGFGMDPFPDDLTASWPDWALPRLSSA
:.. ..::: . :: ::::: :::.:..::. .:.. : .: .:.
NP_001 MTERRVPFSLLRGPSW---DPFRDWYPHSRLFDQAFGLPRLPEE----WSQWL---GGSS
10 20 30 40 50
60 70 80 90 100
pF1KE3 WPGTLRSGMVPRGPTATARFGVPAEGR----------TPPPFPGEPWKVCVNVHSFKPEE
::: .: .: . . ..:: .: . .. :.: ..:. : :.:
NP_001 WPGYVRP--LPPAAIESPAVAAPAYSRALSRQLSSGVSEIRHTADRWRVSLDVNHFAPDE
60 70 80 90 100
110 120 130 140 150 160
pF1KE3 LMVKTKDGYVEVSGKHEEKQQEGGIVSKNFTKKIQLPAEVDPVTVFASLSPEGLLIIEAP
: :::::: ::..:::::.:.: : .:. ::.: :: :::. : .:::::: : .:::
NP_001 LTVKTKDGVVEITGKHEERQDEHGYISRCFTRKYTLPPGVDPTQVSSSLSPEGTLTVEAP
110 120 130 140 150 160
170 180 190
pF1KE3 QVPPYSTFGESSFNNELPQDSQEVTCT
.: .:
NP_001 -MPKLATQSNEITIPVTFESRAQLGGPEAAKSDETAAK
170 180 190 200
>>NP_001317308 (OMIM: 123590,608810,613763,613869,615184 (108 aa)
initn: 224 init1: 224 opt: 243 Z-score: 248.9 bits: 52.0 E(85289): 4e-07
Smith-Waterman score: 243; 45.3% identity (81.3% similar) in 75 aa overlap (96-170:8-82)
70 80 90 100 110 120
pF1KE3 SGMVPRGPTATARFGVPAEGRTPPPFPGEPWKVCVNVHSFKPEELMVKTKDGYVEVSGKH
..: ..:. :.:::: ::. .:: :::
NP_001 MRLEKDRFSVNLDVKHFSPEELKVKVLGDVIEVHGKH
10 20 30
130 140 150 160 170 180
pF1KE3 EEKQQEGGIVSKNFTKKIQLPAEVDPVTVFASLSPEGLLIIEAPQVPPYSTFGESSFNNE
::.:.: :..:..: .: ..::.:::.:. .::: .:.: ...:.
NP_001 EERQDEHGFISREFHRKYRIPADVDPLTITSSLSSDGVLTVNGPRKQVSGPERTIPITRE
40 50 60 70 80 90
190
pF1KE3 LPQDSQEVTCT
NP_001 EKPAVTAAPKK
100
>>NP_001876 (OMIM: 123590,608810,613763,613869,615184) a (175 aa)
initn: 273 init1: 224 opt: 245 Z-score: 247.7 bits: 52.5 E(85289): 4.7e-07
Smith-Waterman score: 284; 35.2% identity (61.2% similar) in 165 aa overlap (6-170:1-149)
10 20 30 40 50 60
pF1KE3 MADGQMPFSCHYPSRLRRDPFRDSPLSSRLLDDGFGMDPFPDDLTASWPDWALPRLSSAW
: .. :.: .:: :: :::.:. :: . .:: .: .:
NP_001 MDIAIHHP-WIRR-PFFPFHSPSRLFDQFFGEHLLESDL--------FPTSTSLS
10 20 30 40
70 80 90 100 110 120
pF1KE3 PGTLRSGMVPRGPTATARFGVPAEGRTPPPFPGEPWKVCVNVHSFKPEELMVKTKDGYVE
: :: :.:. : . : . . . ..: ..:. :.:::: ::. .:
NP_001 PFYLRPPSFLRAPS---WFDT---GLSEMRLEKDRFSVNLDVKHFSPEELKVKVLGDVIE
50 60 70 80 90
130 140 150 160 170 180
pF1KE3 VSGKHEEKQQEGGIVSKNFTKKIQLPAEVDPVTVFASLSPEGLLIIEAPQVPPYSTFGES
: :::::.:.: :..:..: .: ..::.:::.:. .::: .:.: ...:.
NP_001 VHGKHEERQDEHGFISREFHRKYRIPADVDPLTITSSLSSDGVLTVNGPRKQVSGPERTI
100 110 120 130 140 150
190
pF1KE3 SFNNELPQDSQEVTCT
NP_001 PITREEKPAVTAAPKK
160 170
>>NP_001276737 (OMIM: 123590,608810,613763,613869,615184 (175 aa)
initn: 273 init1: 224 opt: 245 Z-score: 247.7 bits: 52.5 E(85289): 4.7e-07
Smith-Waterman score: 284; 35.2% identity (61.2% similar) in 165 aa overlap (6-170:1-149)
10 20 30 40 50 60
pF1KE3 MADGQMPFSCHYPSRLRRDPFRDSPLSSRLLDDGFGMDPFPDDLTASWPDWALPRLSSAW
: .. :.: .:: :: :::.:. :: . .:: .: .:
NP_001 MDIAIHHP-WIRR-PFFPFHSPSRLFDQFFGEHLLESDL--------FPTSTSLS
10 20 30 40
70 80 90 100 110 120
pF1KE3 PGTLRSGMVPRGPTATARFGVPAEGRTPPPFPGEPWKVCVNVHSFKPEELMVKTKDGYVE
: :: :.:. : . : . . . ..: ..:. :.:::: ::. .:
NP_001 PFYLRPPSFLRAPS---WFDT---GLSEMRLEKDRFSVNLDVKHFSPEELKVKVLGDVIE
50 60 70 80 90
130 140 150 160 170 180
pF1KE3 VSGKHEEKQQEGGIVSKNFTKKIQLPAEVDPVTVFASLSPEGLLIIEAPQVPPYSTFGES
: :::::.:.: :..:..: .: ..::.:::.:. .::: .:.: ...:.
NP_001 VHGKHEERQDEHGFISREFHRKYRIPADVDPLTITSSLSSDGVLTVNGPRKQVSGPERTI
100 110 120 130 140 150
190
pF1KE3 SFNNELPQDSQEVTCT
NP_001 PITREEKPAVTAAPKK
160 170
>>NP_001276736 (OMIM: 123590,608810,613763,613869,615184 (175 aa)
initn: 273 init1: 224 opt: 245 Z-score: 247.7 bits: 52.5 E(85289): 4.7e-07
Smith-Waterman score: 284; 35.2% identity (61.2% similar) in 165 aa overlap (6-170:1-149)
10 20 30 40 50 60
pF1KE3 MADGQMPFSCHYPSRLRRDPFRDSPLSSRLLDDGFGMDPFPDDLTASWPDWALPRLSSAW
: .. :.: .:: :: :::.:. :: . .:: .: .:
NP_001 MDIAIHHP-WIRR-PFFPFHSPSRLFDQFFGEHLLESDL--------FPTSTSLS
10 20 30 40
70 80 90 100 110 120
pF1KE3 PGTLRSGMVPRGPTATARFGVPAEGRTPPPFPGEPWKVCVNVHSFKPEELMVKTKDGYVE
: :: :.:. : . : . . . ..: ..:. :.:::: ::. .:
NP_001 PFYLRPPSFLRAPS---WFDT---GLSEMRLEKDRFSVNLDVKHFSPEELKVKVLGDVIE
50 60 70 80 90
130 140 150 160 170 180
pF1KE3 VSGKHEEKQQEGGIVSKNFTKKIQLPAEVDPVTVFASLSPEGLLIIEAPQVPPYSTFGES
: :::::.:.: :..:..: .: ..::.:::.:. .::: .:.: ...:.
NP_001 VHGKHEERQDEHGFISREFHRKYRIPADVDPLTITSSLSSDGVLTVNGPRKQVSGPERTI
100 110 120 130 140 150
190
pF1KE3 SFNNELPQDSQEVTCT
NP_001 PITREEKPAVTAAPKK
160 170
>>XP_011540910 (OMIM: 123590,608810,613763,613869,615184 (175 aa)
initn: 273 init1: 224 opt: 245 Z-score: 247.7 bits: 52.5 E(85289): 4.7e-07
Smith-Waterman score: 284; 35.2% identity (61.2% similar) in 165 aa overlap (6-170:1-149)
10 20 30 40 50 60
pF1KE3 MADGQMPFSCHYPSRLRRDPFRDSPLSSRLLDDGFGMDPFPDDLTASWPDWALPRLSSAW
: .. :.: .:: :: :::.:. :: . .:: .: .:
XP_011 MDIAIHHP-WIRR-PFFPFHSPSRLFDQFFGEHLLESDL--------FPTSTSLS
10 20 30 40
70 80 90 100 110 120
pF1KE3 PGTLRSGMVPRGPTATARFGVPAEGRTPPPFPGEPWKVCVNVHSFKPEELMVKTKDGYVE
: :: :.:. : . : . . . ..: ..:. :.:::: ::. .:
XP_011 PFYLRPPSFLRAPS---WFDT---GLSEMRLEKDRFSVNLDVKHFSPEELKVKVLGDVIE
50 60 70 80 90
130 140 150 160 170 180
pF1KE3 VSGKHEEKQQEGGIVSKNFTKKIQLPAEVDPVTVFASLSPEGLLIIEAPQVPPYSTFGES
: :::::.:.: :..:..: .: ..::.:::.:. .::: .:.: ...:.
XP_011 VHGKHEERQDEHGFISREFHRKYRIPADVDPLTITSSLSSDGVLTVNGPRKQVSGPERTI
100 110 120 130 140 150
190
pF1KE3 SFNNELPQDSQEVTCT
XP_011 PITREEKPAVTAAPKK
160 170
>>NP_653218 (OMIM: 610695) heat shock protein beta-6 [Ho (160 aa)
initn: 249 init1: 192 opt: 238 Z-score: 241.6 bits: 51.2 E(85289): 1e-06
Smith-Waterman score: 247; 35.9% identity (60.5% similar) in 167 aa overlap (13-173:9-155)
10 20 30 40 50
pF1KE3 MADGQMPFSCHYPSRLRRD--PFRDSPLSSRLLDDGFGMDPFPDDLTASWPDWALPRLSS
:: ::: :. .::.:. :: . .:.: : ..
NP_653 MEIPVPVQPSWLRRASAPLPGLSAPGRLFDQRFGEGLLEAELAALCP-------TT
10 20 30 40
60 70 80 90 100 110
pF1KE3 AWPGTLRSGMVPRGPTATARFGVPAEGRTPPPFPGEPWKVCVNVHSFKPEELMVKTKDGY
: ::. : :.: ::.. ::. ..: ..:. :.:::. ::. .
NP_653 LAPYYLRAPSVAL-PVAQ----VPTD-------PGH-FSVLLDVKHFSPEEIAVKVVGEH
50 60 70 80 90
120 130 140 150 160 170
pF1KE3 VEVSGKHEEKQQEGGIVSKNFTKKIQLPAEVDPVTVFASLSPEGLLIIEA-P---QVPPY
::: ..:::. .: :.:...: .. .:: :::..: ..:::::.: :.: : :.::
NP_653 VEVHARHEERPDEHGFVAREFHRRYRLPPGVDPAAVTSALSPEGVLSIQAAPASAQAPPP
100 110 120 130 140 150
180 190
pF1KE3 STFGESSFNNELPQDSQEVTCT
NP_653 AAAK
160
>>XP_005261150 (OMIM: 123580,604219) PREDICTED: alpha-cr (136 aa)
initn: 229 init1: 198 opt: 215 Z-score: 220.9 bits: 47.2 E(85289): 1.5e-05
Smith-Waterman score: 215; 37.8% identity (78.4% similar) in 74 aa overlap (98-171:36-109)
70 80 90 100 110 120
pF1KE3 MVPRGPTATARFGVPAEGRTPPPFPGEPWKVCVNVHSFKPEELMVKTKDGYVEVSGKHEE
. ..:. :.::.: ::..: .::. :::.:
XP_005 GDSHRPPKALPHLVCGRRGRQVRSDRDKFVIFLDVKHFSPEDLTVKVQDDFVEIHGKHNE
10 20 30 40 50 60
130 140 150 160 170 180
pF1KE3 KQQEGGIVSKNFTKKIQLPAEVDPVTVFASLSPEGLLIIEAPQVPPYSTFGESSFNNELP
.:.. : .:..: .. .::..:: .. ::: .:.: . .:..
XP_005 RQDDHGYISREFHRRYRLPSNVDQSALSCSLSADGMLTFCGPKIQTGLDATHAERAIPVS
70 80 90 100 110 120
190
pF1KE3 QDSQEVTCT
XP_005 REEKPTSAPSS
130
>>NP_000385 (OMIM: 123580,604219) alpha-crystallin A cha (173 aa)
initn: 233 init1: 198 opt: 215 Z-score: 219.3 bits: 47.2 E(85289): 1.8e-05
Smith-Waterman score: 227; 31.9% identity (61.8% similar) in 144 aa overlap (28-171:20-146)
10 20 30 40 50 60
pF1KE3 MADGQMPFSCHYPSRLRRDPFRDSPLSSRLLDDGFGMDPFPDDLTASWPDWALPRLSSAW
:::.:. :: : :: :: :::.
NP_000 MDVTIQHPWFKRTLGPFYPSRLFDQFFGEGLFEYDL--------LPFLSSTI
10 20 30 40
70 80 90 100 110 120
pF1KE3 PGTLRSGMVPRGPTATARFGVPAEGRTPPPFPGEPWKVCVNVHSFKPEELMVKTKDGYVE
:... .. :. .: :. . . . ..:. :.::.: ::..: .::
NP_000 SPYYRQSLF----RTVLDSGI-SEVRSDR----DKFVIFLDVKHFSPEDLTVKVQDDFVE
50 60 70 80 90
130 140 150 160 170 180
pF1KE3 VSGKHEEKQQEGGIVSKNFTKKIQLPAEVDPVTVFASLSPEGLLIIEAPQVPPYSTFGES
. :::.:.:.. : .:..: .. .::..:: .. ::: .:.: . .:..
NP_000 IHGKHNERQDDHGYISREFHRRYRLPSNVDQSALSCSLSADGMLTFCGPKIQTGLDATHA
100 110 120 130 140 150
190
pF1KE3 SFNNELPQDSQEVTCT
NP_000 ERAIPVSREEKPTSAPSS
160 170
196 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 02:37:02 2016 done: Mon Nov 7 02:37:03 2016
Total Scan time: 6.000 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]