Result of FASTA (omim) for
pFN21AE3659
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3659, 175 aa
1>>>pF1KE3659 175 - 175 aa - 175 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.0782+/-0.000264; mu= 20.4708+/- 0.017
mean_var=67.4990+/-13.602, 0's: 0 Z-trim(119.5): 12 B-trim: 0 in 0/58
Lambda= 0.156108
statistics sampled from 33531 (33543) to 33531 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.762), E-opt: 0.2 (0.393), width: 16
Scan time: 6.070
The best scores are: opt bits E(85289)
NP_005845 (OMIM: 605154) receptor activity-modifyi ( 175) 1214 281.1 6.1e-76
XP_016858642 (OMIM: 605153) PREDICTED: receptor ac ( 126) 248 63.4 1.5e-10
XP_016858641 (OMIM: 605153) PREDICTED: receptor ac ( 126) 248 63.4 1.5e-10
NP_001295282 (OMIM: 605153) receptor activity-modi ( 126) 248 63.4 1.5e-10
XP_016858643 (OMIM: 605153) PREDICTED: receptor ac ( 126) 248 63.4 1.5e-10
XP_016858645 (OMIM: 605153) PREDICTED: receptor ac ( 126) 248 63.4 1.5e-10
NP_005847 (OMIM: 605155) receptor activity-modifyi ( 148) 248 63.5 1.7e-10
NP_005846 (OMIM: 605153) receptor activity-modifyi ( 148) 248 63.5 1.7e-10
XP_006715694 (OMIM: 605155) PREDICTED: receptor ac ( 259) 246 63.3 3.3e-10
XP_016867155 (OMIM: 605155) PREDICTED: receptor ac ( 116) 239 61.3 5.9e-10
>>NP_005845 (OMIM: 605154) receptor activity-modifying p (175 aa)
initn: 1214 init1: 1214 opt: 1214 Z-score: 1484.4 bits: 281.1 E(85289): 6.1e-76
Smith-Waterman score: 1214; 100.0% identity (100.0% similar) in 175 aa overlap (1-175:1-175)
10 20 30 40 50 60
pF1KE3 MASLRVERAGGPRLPRTRVGRPAALRLLLLLGAVLNPHEALAQPLPTTGTPGSEGGTVKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MASLRVERAGGPRLPRTRVGRPAALRLLLLLGAVLNPHEALAQPLPTTGTPGSEGGTVKN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 YETAVQFCWNHYKDQMDPIEKDWCDWAMISRPYSTLRDCLEHFAELFDLGFPNPLAERII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 YETAVQFCWNHYKDQMDPIEKDWCDWAMISRPYSTLRDCLEHFAELFDLGFPNPLAERII
70 80 90 100 110 120
130 140 150 160 170
pF1KE3 FETHQIHFANCSLVQPTFSDPPEDVLLAMIIAPICLIPFLITLVVWRSKDSEAQA
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 FETHQIHFANCSLVQPTFSDPPEDVLLAMIIAPICLIPFLITLVVWRSKDSEAQA
130 140 150 160 170
>>XP_016858642 (OMIM: 605153) PREDICTED: receptor activi (126 aa)
initn: 256 init1: 230 opt: 248 Z-score: 310.2 bits: 63.4 E(85289): 1.5e-10
Smith-Waterman score: 248; 32.4% identity (63.9% similar) in 108 aa overlap (66-172:16-123)
40 50 60 70 80 90
pF1KE3 NPHEALAQPLPTTGTPGSEGGTVKNYETAVQFCWNHYKDQMDPI-EKDWCDWAMISRPYS
..: .... .:. . : ::::. : :
XP_016 MTTACQEANYGALLRELCLTQFQVDMEAVGETLWCDWGRTIRSYR
10 20 30 40
100 110 120 130 140 150
pF1KE3 TLRDCLEHFAELFDLGFPNPLAERIIFETHQIHFANCSLVQPTFSDPPEDVLLAMIIAPI
: :: :.:: . .:: ..:... .: .: .: . . ::: ..: .:..::
XP_016 ELADCTWHMAEKLGCFWPNAEVDRFFLAVHGRYFRSCPISGRAVRDPPGSILYPFIVVPI
50 60 70 80 90 100
160 170
pF1KE3 CLIPFLITLVVWRSKDSEAQA
. .. .::::.:: .:
XP_016 TVTLLVTALVVWQSKRTEGIV
110 120
>>XP_016858641 (OMIM: 605153) PREDICTED: receptor activi (126 aa)
initn: 256 init1: 230 opt: 248 Z-score: 310.2 bits: 63.4 E(85289): 1.5e-10
Smith-Waterman score: 248; 32.4% identity (63.9% similar) in 108 aa overlap (66-172:16-123)
40 50 60 70 80 90
pF1KE3 NPHEALAQPLPTTGTPGSEGGTVKNYETAVQFCWNHYKDQMDPI-EKDWCDWAMISRPYS
..: .... .:. . : ::::. : :
XP_016 MTTACQEANYGALLRELCLTQFQVDMEAVGETLWCDWGRTIRSYR
10 20 30 40
100 110 120 130 140 150
pF1KE3 TLRDCLEHFAELFDLGFPNPLAERIIFETHQIHFANCSLVQPTFSDPPEDVLLAMIIAPI
: :: :.:: . .:: ..:... .: .: .: . . ::: ..: .:..::
XP_016 ELADCTWHMAEKLGCFWPNAEVDRFFLAVHGRYFRSCPISGRAVRDPPGSILYPFIVVPI
50 60 70 80 90 100
160 170
pF1KE3 CLIPFLITLVVWRSKDSEAQA
. .. .::::.:: .:
XP_016 TVTLLVTALVVWQSKRTEGIV
110 120
>>NP_001295282 (OMIM: 605153) receptor activity-modifyin (126 aa)
initn: 256 init1: 230 opt: 248 Z-score: 310.2 bits: 63.4 E(85289): 1.5e-10
Smith-Waterman score: 248; 32.4% identity (63.9% similar) in 108 aa overlap (66-172:16-123)
40 50 60 70 80 90
pF1KE3 NPHEALAQPLPTTGTPGSEGGTVKNYETAVQFCWNHYKDQMDPI-EKDWCDWAMISRPYS
..: .... .:. . : ::::. : :
NP_001 MTTACQEANYGALLRELCLTQFQVDMEAVGETLWCDWGRTIRSYR
10 20 30 40
100 110 120 130 140 150
pF1KE3 TLRDCLEHFAELFDLGFPNPLAERIIFETHQIHFANCSLVQPTFSDPPEDVLLAMIIAPI
: :: :.:: . .:: ..:... .: .: .: . . ::: ..: .:..::
NP_001 ELADCTWHMAEKLGCFWPNAEVDRFFLAVHGRYFRSCPISGRAVRDPPGSILYPFIVVPI
50 60 70 80 90 100
160 170
pF1KE3 CLIPFLITLVVWRSKDSEAQA
. .. .::::.:: .:
NP_001 TVTLLVTALVVWQSKRTEGIV
110 120
>>XP_016858643 (OMIM: 605153) PREDICTED: receptor activi (126 aa)
initn: 256 init1: 230 opt: 248 Z-score: 310.2 bits: 63.4 E(85289): 1.5e-10
Smith-Waterman score: 248; 32.4% identity (63.9% similar) in 108 aa overlap (66-172:16-123)
40 50 60 70 80 90
pF1KE3 NPHEALAQPLPTTGTPGSEGGTVKNYETAVQFCWNHYKDQMDPI-EKDWCDWAMISRPYS
..: .... .:. . : ::::. : :
XP_016 MTTACQEANYGALLRELCLTQFQVDMEAVGETLWCDWGRTIRSYR
10 20 30 40
100 110 120 130 140 150
pF1KE3 TLRDCLEHFAELFDLGFPNPLAERIIFETHQIHFANCSLVQPTFSDPPEDVLLAMIIAPI
: :: :.:: . .:: ..:... .: .: .: . . ::: ..: .:..::
XP_016 ELADCTWHMAEKLGCFWPNAEVDRFFLAVHGRYFRSCPISGRAVRDPPGSILYPFIVVPI
50 60 70 80 90 100
160 170
pF1KE3 CLIPFLITLVVWRSKDSEAQA
. .. .::::.:: .:
XP_016 TVTLLVTALVVWQSKRTEGIV
110 120
>>XP_016858645 (OMIM: 605153) PREDICTED: receptor activi (126 aa)
initn: 256 init1: 230 opt: 248 Z-score: 310.2 bits: 63.4 E(85289): 1.5e-10
Smith-Waterman score: 248; 32.4% identity (63.9% similar) in 108 aa overlap (66-172:16-123)
40 50 60 70 80 90
pF1KE3 NPHEALAQPLPTTGTPGSEGGTVKNYETAVQFCWNHYKDQMDPI-EKDWCDWAMISRPYS
..: .... .:. . : ::::. : :
XP_016 MTTACQEANYGALLRELCLTQFQVDMEAVGETLWCDWGRTIRSYR
10 20 30 40
100 110 120 130 140 150
pF1KE3 TLRDCLEHFAELFDLGFPNPLAERIIFETHQIHFANCSLVQPTFSDPPEDVLLAMIIAPI
: :: :.:: . .:: ..:... .: .: .: . . ::: ..: .:..::
XP_016 ELADCTWHMAEKLGCFWPNAEVDRFFLAVHGRYFRSCPISGRAVRDPPGSILYPFIVVPI
50 60 70 80 90 100
160 170
pF1KE3 CLIPFLITLVVWRSKDSEAQA
. .. .::::.:: .:
XP_016 TVTLLVTALVVWQSKRTEGIV
110 120
>>NP_005847 (OMIM: 605155) receptor activity-modifying p (148 aa)
initn: 285 init1: 224 opt: 248 Z-score: 309.4 bits: 63.5 E(85289): 1.7e-10
Smith-Waterman score: 248; 28.9% identity (56.3% similar) in 142 aa overlap (32-172:4-145)
10 20 30 40 50 60
pF1KE3 ASLRVERAGGPRLPRTRVGRPAALRLLLLLGAVLNPHEALAQPLPTTGTPGSEGGTVKNY
::. :. : : : . : . ..
NP_005 METGALRRPQLLPLLLLLCGGCPRAGGCNETGM
10 20 30
70 80 90 100 110 120
pF1KE3 ETAVQFCWNHYKDQMDPIEK-DWCDWAMISRPYSTLRDCLEHFAELFDLGFPNPLAERII
. .: . . :.: .. ::. . . : .. .: : :.. .:::::. .:
NP_005 LERLPLCGKAFADMMGKVDVWKWCNLSEFIVYYESFTNCTEMEANVVGCYWPNPLAQGFI
40 50 60 70 80 90
130 140 150 160 170
pF1KE3 FETHQIHFANCSLVQPTFSDPPEDVLLAMIIAPICLIPFLITLVVWRSKDSEAQA
:. :.::.. . . :::..::. .:. :. : . ::::::: ..
NP_005 TGIHRQFFSNCTVDRVHLEDPPDEVLIPLIVIPVVLTVAMAGLVVWRSKRTDTLL
100 110 120 130 140
>>NP_005846 (OMIM: 605153) receptor activity-modifying p (148 aa)
initn: 259 init1: 230 opt: 248 Z-score: 309.4 bits: 63.5 E(85289): 1.7e-10
Smith-Waterman score: 248; 32.4% identity (63.9% similar) in 108 aa overlap (66-172:38-145)
40 50 60 70 80 90
pF1KE3 NPHEALAQPLPTTGTPGSEGGTVKNYETAVQFCWNHYKDQMDPI-EKDWCDWAMISRPYS
..: .... .:. . : ::::. : :
NP_005 LPRRGLWLLLAHHLFMTTACQEANYGALLRELCLTQFQVDMEAVGETLWCDWGRTIRSYR
10 20 30 40 50 60
100 110 120 130 140 150
pF1KE3 TLRDCLEHFAELFDLGFPNPLAERIIFETHQIHFANCSLVQPTFSDPPEDVLLAMIIAPI
: :: :.:: . .:: ..:... .: .: .: . . ::: ..: .:..::
NP_005 ELADCTWHMAEKLGCFWPNAEVDRFFLAVHGRYFRSCPISGRAVRDPPGSILYPFIVVPI
70 80 90 100 110 120
160 170
pF1KE3 CLIPFLITLVVWRSKDSEAQA
. .. .::::.:: .:
NP_005 TVTLLVTALVVWQSKRTEGIV
130 140
>>XP_006715694 (OMIM: 605155) PREDICTED: receptor activi (259 aa)
initn: 296 init1: 224 opt: 246 Z-score: 304.2 bits: 63.3 E(85289): 3.3e-10
Smith-Waterman score: 246; 29.6% identity (59.2% similar) in 125 aa overlap (49-172:132-256)
20 30 40 50 60 70
pF1KE3 VGRPAALRLLLLLGAVLNPHEALAQPLPTTGTPGSEGGTVKNYETAVQFCWNHYKDQMDP
: : . : . .. . .: . . :.:
XP_006 LSSGSVPVGHLEGGTVKLQKDTGLHSCRDGGCPRAGGCNETGMLERLPLCGKAFADMMGK
110 120 130 140 150 160
80 90 100 110 120 130
pF1KE3 IEK-DWCDWAMISRPYSTLRDCLEHFAELFDLGFPNPLAERIIFETHQIHFANCSLVQPT
.. ::. . . : .. .: : :.. .:::::. .: :. :.::.. .
XP_006 VDVWKWCNLSEFIVYYESFTNCTEMEANVVGCYWPNPLAQGFITGIHRQFFSNCTVDRVH
170 180 190 200 210 220
140 150 160 170
pF1KE3 FSDPPEDVLLAMIIAPICLIPFLITLVVWRSKDSEAQA
. :::..::. .:. :. : . ::::::: ..
XP_006 LEDPPDEVLIPLIVIPVVLTVAMAGLVVWRSKRTDTLL
230 240 250
>>XP_016867155 (OMIM: 605155) PREDICTED: receptor activi (116 aa)
initn: 258 init1: 224 opt: 239 Z-score: 299.7 bits: 61.3 E(85289): 5.9e-10
Smith-Waterman score: 239; 31.8% identity (61.7% similar) in 107 aa overlap (67-172:7-113)
40 50 60 70 80 90
pF1KE3 PHEALAQPLPTTGTPGSEGGTVKNYETAVQFCWNHYKDQMDPIEK-DWCDWAMISRPYST
.: . . :.: .. ::. . . : .
XP_016 MLERLPLCGKAFADMMGKVDVWKWCNLSEFIVYYES
10 20 30
100 110 120 130 140 150
pF1KE3 LRDCLEHFAELFDLGFPNPLAERIIFETHQIHFANCSLVQPTFSDPPEDVLLAMIIAPIC
. .: : :.. .:::::. .: :. :.::.. . . :::..::. .:. :.
XP_016 FTNCTEMEANVVGCYWPNPLAQGFITGIHRQFFSNCTVDRVHLEDPPDEVLIPLIVIPVV
40 50 60 70 80 90
160 170
pF1KE3 LIPFLITLVVWRSKDSEAQA
: . ::::::: ..
XP_016 LTVAMAGLVVWRSKRTDTLL
100 110
175 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 00:23:00 2016 done: Mon Nov 7 00:23:01 2016
Total Scan time: 6.070 Total Display time: -0.030
Function used was FASTA [36.3.4 Apr, 2011]