Result of FASTA (omim) for
pFN21AE3653
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3653, 293 aa
1>>>pF1KE3653 293 - 293 aa - 293 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.3030+/-0.000307; mu= 16.2652+/- 0.019
mean_var=79.3537+/-16.220, 0's: 0 Z-trim(117.4): 303 B-trim: 147 in 1/53
Lambda= 0.143976
statistics sampled from 29125 (29440) to 29125 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.719), E-opt: 0.2 (0.345), width: 16
Scan time: 7.470
The best scores are: opt bits E(85289)
NP_036559 (OMIM: 605643) kallikrein-5 preproprotei ( 293) 2073 439.7 3.1e-123
XP_011525005 (OMIM: 605643) PREDICTED: kallikrein- ( 293) 2073 439.7 3.1e-123
XP_011525004 (OMIM: 605643) PREDICTED: kallikrein- ( 293) 2073 439.7 3.1e-123
NP_001070960 (OMIM: 605643) kallikrein-5 prepropro ( 293) 2073 439.7 3.1e-123
NP_001070959 (OMIM: 605643) kallikrein-5 prepropro ( 293) 2073 439.7 3.1e-123
NP_001129504 (OMIM: 604434) kallikrein-11 isoform ( 250) 878 191.4 1.5e-48
NP_006844 (OMIM: 604434) kallikrein-11 isoform 1 p ( 250) 878 191.4 1.5e-48
NP_659196 (OMIM: 604434) kallikrein-11 isoform 2 [ ( 282) 878 191.5 1.6e-48
NP_653088 (OMIM: 605644) kallikrein-8 isoform 2 pr ( 305) 869 189.6 6.2e-48
NP_004908 (OMIM: 204700,603767) kallikrein-4 isofo ( 254) 868 189.4 6.3e-48
NP_009127 (OMIM: 605644) kallikrein-8 isoform 1 pr ( 260) 863 188.3 1.3e-47
NP_071329 (OMIM: 606135) kallikrein-14 preproprote ( 267) 833 182.1 1e-45
NP_001298111 (OMIM: 606135) kallikrein-14 prepropr ( 267) 833 182.1 1e-45
NP_056411 (OMIM: 605505) kallikrein-13 precursor [ ( 277) 828 181.1 2.1e-45
NP_644806 (OMIM: 604438) kallikrein-7 isoform 1 pr ( 253) 817 178.8 9.7e-45
NP_005037 (OMIM: 604438) kallikrein-7 isoform 1 pr ( 253) 817 178.8 9.7e-45
NP_036447 (OMIM: 605504) kallikrein-9 precursor [H ( 250) 815 178.4 1.3e-44
NP_001012982 (OMIM: 602652) kallikrein-6 isoform A ( 244) 772 169.4 6.1e-42
NP_002765 (OMIM: 602652) kallikrein-6 isoform A pr ( 244) 772 169.4 6.1e-42
NP_665901 (OMIM: 605539) kallikrein-12 isoform 2 p ( 248) 767 168.4 1.3e-41
NP_002760 (OMIM: 167800,276000,614044) trypsin-1 p ( 247) 758 166.5 4.6e-41
XP_011514713 (OMIM: 167800,276000,614044) PREDICTE ( 472) 758 166.7 7.6e-41
NP_062544 (OMIM: 605539) kallikrein-12 isoform 1 p ( 254) 733 161.3 1.7e-39
NP_001184027 (OMIM: 613578) trypsin-3 isoform 4 pr ( 240) 722 159.0 8.1e-39
XP_011516267 (OMIM: 613578) PREDICTED: trypsin-3 i ( 333) 718 158.3 1.8e-38
NP_002762 (OMIM: 613578) trypsin-3 isoform 2 prepr ( 247) 711 156.7 4e-38
NP_001184026 (OMIM: 613578) trypsin-3 isoform 3 pr ( 261) 711 156.8 4.2e-38
NP_031369 (OMIM: 613578) trypsin-3 isoform 1 prepr ( 304) 711 156.8 4.7e-38
NP_002761 (OMIM: 167800,601564) trypsin-2 isoform ( 247) 702 154.9 1.5e-37
XP_011524675 (OMIM: 604434) PREDICTED: kallikrein- ( 275) 694 153.3 5e-37
XP_011524672 (OMIM: 604434) PREDICTED: kallikrein- ( 275) 694 153.3 5e-37
NP_001161077 (OMIM: 604434) kallikrein-11 isoform ( 275) 694 153.3 5e-37
XP_011524674 (OMIM: 604434) PREDICTED: kallikrein- ( 275) 694 153.3 5e-37
XP_011524673 (OMIM: 604434) PREDICTED: kallikrein- ( 275) 694 153.3 5e-37
XP_011524671 (OMIM: 604434) PREDICTED: kallikrein- ( 307) 694 153.3 5.5e-37
XP_005259119 (OMIM: 602673) PREDICTED: kallikrein- ( 276) 642 142.5 9e-34
XP_016882482 (OMIM: 602673) PREDICTED: kallikrein- ( 276) 642 142.5 9e-34
NP_665895 (OMIM: 602673) kallikrein-10 preproprote ( 276) 642 142.5 9e-34
XP_006723352 (OMIM: 602673) PREDICTED: kallikrein- ( 276) 642 142.5 9e-34
NP_002767 (OMIM: 602673) kallikrein-10 preproprote ( 276) 642 142.5 9e-34
XP_005259118 (OMIM: 602673) PREDICTED: kallikrein- ( 276) 642 142.5 9e-34
NP_001070968 (OMIM: 602673) kallikrein-10 prepropr ( 276) 642 142.5 9e-34
XP_006723350 (OMIM: 602673) PREDICTED: kallikrein- ( 276) 642 142.5 9e-34
NP_001230055 (OMIM: 604438) kallikrein-7 isoform 3 ( 246) 640 142.0 1.1e-33
NP_001193982 (OMIM: 604438) kallikrein-7 isoform 2 ( 181) 620 137.7 1.6e-32
XP_005259498 (OMIM: 204700,603767) PREDICTED: kall ( 159) 593 132.1 6.9e-31
NP_001289890 (OMIM: 204700,603767) kallikrein-4 is ( 159) 593 132.1 6.9e-31
NP_001290343 (OMIM: 167800,601564) trypsin-2 isofo ( 261) 587 131.0 2.4e-30
NP_001268360 (OMIM: 605644) kallikrein-8 isoform 5 ( 139) 577 128.7 6.2e-30
NP_001306877 (OMIM: 602652) kallikrein-6 isoform B ( 137) 515 115.8 4.6e-26
>>NP_036559 (OMIM: 605643) kallikrein-5 preproprotein [H (293 aa)
initn: 2073 init1: 2073 opt: 2073 Z-score: 2333.3 bits: 439.7 E(85289): 3.1e-123
Smith-Waterman score: 2073; 99.7% identity (99.7% similar) in 293 aa overlap (1-293:1-293)
10 20 30 40 50 60
pF1KE3 MATARPPWMWVLCALITALLLGVTEHVLANNDVSSDHPSNTVPSGSNQDLGAGAGEDARS
:::::::::::::::::::::::::::::::::: :::::::::::::::::::::::::
NP_036 MATARPPWMWVLCALITALLLGVTEHVLANNDVSCDHPSNTVPSGSNQDLGAGAGEDARS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 DDSSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 DDSSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 YSLSPVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHCPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 YSLSPVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHCPS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 AGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGDKAGRDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 AGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGDKAGRDS
190 200 210 220 230 240
250 260 270 280 290
pF1KE3 CQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQANS
:::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 CQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQANS
250 260 270 280 290
>>XP_011525005 (OMIM: 605643) PREDICTED: kallikrein-5 is (293 aa)
initn: 2073 init1: 2073 opt: 2073 Z-score: 2333.3 bits: 439.7 E(85289): 3.1e-123
Smith-Waterman score: 2073; 99.7% identity (99.7% similar) in 293 aa overlap (1-293:1-293)
10 20 30 40 50 60
pF1KE3 MATARPPWMWVLCALITALLLGVTEHVLANNDVSSDHPSNTVPSGSNQDLGAGAGEDARS
:::::::::::::::::::::::::::::::::: :::::::::::::::::::::::::
XP_011 MATARPPWMWVLCALITALLLGVTEHVLANNDVSCDHPSNTVPSGSNQDLGAGAGEDARS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 DDSSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DDSSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 YSLSPVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHCPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YSLSPVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHCPS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 AGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGDKAGRDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGDKAGRDS
190 200 210 220 230 240
250 260 270 280 290
pF1KE3 CQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQANS
:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQANS
250 260 270 280 290
>>XP_011525004 (OMIM: 605643) PREDICTED: kallikrein-5 is (293 aa)
initn: 2073 init1: 2073 opt: 2073 Z-score: 2333.3 bits: 439.7 E(85289): 3.1e-123
Smith-Waterman score: 2073; 99.7% identity (99.7% similar) in 293 aa overlap (1-293:1-293)
10 20 30 40 50 60
pF1KE3 MATARPPWMWVLCALITALLLGVTEHVLANNDVSSDHPSNTVPSGSNQDLGAGAGEDARS
:::::::::::::::::::::::::::::::::: :::::::::::::::::::::::::
XP_011 MATARPPWMWVLCALITALLLGVTEHVLANNDVSCDHPSNTVPSGSNQDLGAGAGEDARS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 DDSSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DDSSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 YSLSPVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHCPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YSLSPVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHCPS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 AGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGDKAGRDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGDKAGRDS
190 200 210 220 230 240
250 260 270 280 290
pF1KE3 CQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQANS
:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQANS
250 260 270 280 290
>>NP_001070960 (OMIM: 605643) kallikrein-5 preproprotein (293 aa)
initn: 2073 init1: 2073 opt: 2073 Z-score: 2333.3 bits: 439.7 E(85289): 3.1e-123
Smith-Waterman score: 2073; 99.7% identity (99.7% similar) in 293 aa overlap (1-293:1-293)
10 20 30 40 50 60
pF1KE3 MATARPPWMWVLCALITALLLGVTEHVLANNDVSSDHPSNTVPSGSNQDLGAGAGEDARS
:::::::::::::::::::::::::::::::::: :::::::::::::::::::::::::
NP_001 MATARPPWMWVLCALITALLLGVTEHVLANNDVSCDHPSNTVPSGSNQDLGAGAGEDARS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 DDSSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DDSSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 YSLSPVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHCPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YSLSPVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHCPS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 AGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGDKAGRDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGDKAGRDS
190 200 210 220 230 240
250 260 270 280 290
pF1KE3 CQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQANS
:::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQANS
250 260 270 280 290
>>NP_001070959 (OMIM: 605643) kallikrein-5 preproprotein (293 aa)
initn: 2073 init1: 2073 opt: 2073 Z-score: 2333.3 bits: 439.7 E(85289): 3.1e-123
Smith-Waterman score: 2073; 99.7% identity (99.7% similar) in 293 aa overlap (1-293:1-293)
10 20 30 40 50 60
pF1KE3 MATARPPWMWVLCALITALLLGVTEHVLANNDVSSDHPSNTVPSGSNQDLGAGAGEDARS
:::::::::::::::::::::::::::::::::: :::::::::::::::::::::::::
NP_001 MATARPPWMWVLCALITALLLGVTEHVLANNDVSCDHPSNTVPSGSNQDLGAGAGEDARS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 DDSSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DDSSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 YSLSPVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHCPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YSLSPVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHCPS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 AGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGDKAGRDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGDKAGRDS
190 200 210 220 230 240
250 260 270 280 290
pF1KE3 CQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQANS
:::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQANS
250 260 270 280 290
>>NP_001129504 (OMIM: 604434) kallikrein-11 isoform 1 pr (250 aa)
initn: 785 init1: 330 opt: 878 Z-score: 992.8 bits: 191.4 E(85289): 1.5e-48
Smith-Waterman score: 878; 51.1% identity (81.1% similar) in 233 aa overlap (65-292:20-250)
40 50 60 70 80 90
pF1KE3 SDHPSNTVPSGSNQDLGAGAGEDARSDDSSSRIINGSDCDMHTQPWQAALLLRPNQLYCG
.:::.: .: :.:::::::. . ..: ::
NP_001 MRILQLILLALATGLVGGETRIIKGFECKPHSQPWQAALFEK-TRLLCG
10 20 30 40
100 110 120 130 140 150
pF1KE3 AVLVHPQWLLTAAHCRKKVFRVRLGHYSLSPVYESGQQMFQGVKSIPHPGYSH--PG--H
:.:. :.:::::::: : . :.::...:. :. .: ...:.::::... :. :
NP_001 ATLIAPRWLLTAAHCLKPRYIVHLGQHNLQK-EEGCEQTRTATESFPHPGFNNSLPNKDH
50 60 70 80 90 100
160 170 180 190 200 210
pF1KE3 SNDLMLIKLNRRIRPTKDVRPINVSSHCPSAGTKCLVSGWGTTKSPQVHFPKVLQCLNIS
::.::.:. . : :::...::.: .:::.::.::::.:.:::...:..:.: ::.
NP_001 RNDIMLVKMASPVSITWAVRPLTLSSRCVTAGTSCLISGWGSTSSPQLRLPHTLRCANIT
110 120 130 140 150 160
220 230 240 250 260
pF1KE3 VLSQKRCEDAYPRQIDDTMFCAG-DKAGRDSCQGDSGGPVVCNGSLQGLVSWGDYPCARP
.. ...::.::: .: ::: ::. ...:.::::::::::.::: ::::..:::. :::
NP_001 IIEHQKCENAYPGNITDTMVCASVQEGGKDSCQGDSGGPLVCNQSLQGIISWGQDPCAIT
170 180 190 200 210 220
270 280 290
pF1KE3 NRPGVYTNLCKFTKWIQETIQANS
.:::::..::.. :::::.. :
NP_001 RKPGVYTKVCKYVDWIQETMKNN
230 240 250
>>NP_006844 (OMIM: 604434) kallikrein-11 isoform 1 precu (250 aa)
initn: 785 init1: 330 opt: 878 Z-score: 992.8 bits: 191.4 E(85289): 1.5e-48
Smith-Waterman score: 878; 51.1% identity (81.1% similar) in 233 aa overlap (65-292:20-250)
40 50 60 70 80 90
pF1KE3 SDHPSNTVPSGSNQDLGAGAGEDARSDDSSSRIINGSDCDMHTQPWQAALLLRPNQLYCG
.:::.: .: :.:::::::. . ..: ::
NP_006 MRILQLILLALATGLVGGETRIIKGFECKPHSQPWQAALFEK-TRLLCG
10 20 30 40
100 110 120 130 140 150
pF1KE3 AVLVHPQWLLTAAHCRKKVFRVRLGHYSLSPVYESGQQMFQGVKSIPHPGYSH--PG--H
:.:. :.:::::::: : . :.::...:. :. .: ...:.::::... :. :
NP_006 ATLIAPRWLLTAAHCLKPRYIVHLGQHNLQK-EEGCEQTRTATESFPHPGFNNSLPNKDH
50 60 70 80 90 100
160 170 180 190 200 210
pF1KE3 SNDLMLIKLNRRIRPTKDVRPINVSSHCPSAGTKCLVSGWGTTKSPQVHFPKVLQCLNIS
::.::.:. . : :::...::.: .:::.::.::::.:.:::...:..:.: ::.
NP_006 RNDIMLVKMASPVSITWAVRPLTLSSRCVTAGTSCLISGWGSTSSPQLRLPHTLRCANIT
110 120 130 140 150 160
220 230 240 250 260
pF1KE3 VLSQKRCEDAYPRQIDDTMFCAG-DKAGRDSCQGDSGGPVVCNGSLQGLVSWGDYPCARP
.. ...::.::: .: ::: ::. ...:.::::::::::.::: ::::..:::. :::
NP_006 IIEHQKCENAYPGNITDTMVCASVQEGGKDSCQGDSGGPLVCNQSLQGIISWGQDPCAIT
170 180 190 200 210 220
270 280 290
pF1KE3 NRPGVYTNLCKFTKWIQETIQANS
.:::::..::.. :::::.. :
NP_006 RKPGVYTKVCKYVDWIQETMKNN
230 240 250
>>NP_659196 (OMIM: 604434) kallikrein-11 isoform 2 [Homo (282 aa)
initn: 785 init1: 330 opt: 878 Z-score: 992.1 bits: 191.5 E(85289): 1.6e-48
Smith-Waterman score: 878; 51.1% identity (81.1% similar) in 233 aa overlap (65-292:52-282)
40 50 60 70 80 90
pF1KE3 SDHPSNTVPSGSNQDLGAGAGEDARSDDSSSRIINGSDCDMHTQPWQAALLLRPNQLYCG
.:::.: .: :.:::::::. . ..: ::
NP_659 EPGARSSPLQAMRILQLILLALATGLVGGETRIIKGFECKPHSQPWQAALFEK-TRLLCG
30 40 50 60 70 80
100 110 120 130 140 150
pF1KE3 AVLVHPQWLLTAAHCRKKVFRVRLGHYSLSPVYESGQQMFQGVKSIPHPGYSH--PG--H
:.:. :.:::::::: : . :.::...:. :. .: ...:.::::... :. :
NP_659 ATLIAPRWLLTAAHCLKPRYIVHLGQHNLQK-EEGCEQTRTATESFPHPGFNNSLPNKDH
90 100 110 120 130
160 170 180 190 200 210
pF1KE3 SNDLMLIKLNRRIRPTKDVRPINVSSHCPSAGTKCLVSGWGTTKSPQVHFPKVLQCLNIS
::.::.:. . : :::...::.: .:::.::.::::.:.:::...:..:.: ::.
NP_659 RNDIMLVKMASPVSITWAVRPLTLSSRCVTAGTSCLISGWGSTSSPQLRLPHTLRCANIT
140 150 160 170 180 190
220 230 240 250 260
pF1KE3 VLSQKRCEDAYPRQIDDTMFCAG-DKAGRDSCQGDSGGPVVCNGSLQGLVSWGDYPCARP
.. ...::.::: .: ::: ::. ...:.::::::::::.::: ::::..:::. :::
NP_659 IIEHQKCENAYPGNITDTMVCASVQEGGKDSCQGDSGGPLVCNQSLQGIISWGQDPCAIT
200 210 220 230 240 250
270 280 290
pF1KE3 NRPGVYTNLCKFTKWIQETIQANS
.:::::..::.. :::::.. :
NP_659 RKPGVYTKVCKYVDWIQETMKNN
260 270 280
>>NP_653088 (OMIM: 605644) kallikrein-8 isoform 2 precur (305 aa)
initn: 762 init1: 590 opt: 869 Z-score: 981.5 bits: 189.6 E(85289): 6.2e-48
Smith-Waterman score: 869; 44.6% identity (71.1% similar) in 287 aa overlap (10-289:22-301)
10 20 30 40
pF1KE3 MATARPPWMWVLCA---LITALLLGVTEHVLANNDVSSDHPSNTVPSG
:. :. :.: : : : . : .::. : :
NP_653 MGRPRPRAAKTWMFLLLLGGAWAACGSLDLLTKLYAENLPCVHLNPQWPS-QPSHC-PRG
10 20 30 40 50
50 60 70 80 90 100
pF1KE3 -SNQDLGAGAGEDARSDDSSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLL
.. : .::.. ..: ....: .:. :.:::::::. . .:: ::.::: .:.:
NP_653 WRSNPLPPAAGHSRAQED---KVLGGHECQPHSQPWQAALF-QGQQLLCGGVLVGGNWVL
60 70 80 90 100 110
110 120 130 140 150 160
pF1KE3 TAAHCRKKVFRVRLGHYSLSPVYESGQQMFQGVKSIPHPGYSHPG---HSNDLMLIKLNR
:::::.: . :::: .::. .. .: . :.::::: :. :..::::..:
NP_653 TAAHCKKPKYTVRLGDHSLQN-KDGPEQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRD
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE3 RIRPTKDVRPINVSSHCPSAGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAY
. . :.::....:: . : :: ::::::. ::. .:: .:.: ..... ::.:::::
NP_653 QASLGSKVKPISLADHCTQPGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAY
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE3 PRQIDDTMFCAGDKAGRDSCQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKF
: :: : : :::.. : :.::::::::.::.:.:::..:::. ::.: ..::::::.:..
NP_653 PGQITDGMVCAGSSKGADTCQGDSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRY
240 250 260 270 280 290
290
pF1KE3 TKWIQETIQANS
::.. :
NP_653 LDWIKKIIGSKG
300
>>NP_004908 (OMIM: 204700,603767) kallikrein-4 isoform 1 (254 aa)
initn: 813 init1: 385 opt: 868 Z-score: 981.5 bits: 189.4 E(85289): 6.3e-48
Smith-Waterman score: 868; 51.5% identity (77.1% similar) in 231 aa overlap (63-292:27-254)
40 50 60 70 80 90
pF1KE3 VSSDHPSNTVPSGSNQDLGAGAGEDARSDDSSSRIINGSDCDMHTQPWQAALLLRPNQLY
: :.:::: ::. :.:::::::... :.:.
NP_004 MATAGNPWGWFLGYLILGVAGSLVSGSCSQIINGEDCSPHSQPWQAALVME-NELF
10 20 30 40 50
100 110 120 130 140 150
pF1KE3 CGAVLVHPQWLLTAAHCRKKVFRVRLGHYSLSPVYESGQQMFQGVKSIPHPGYSHPGHSN
:..:::::::.:.:::: .. . . :: .:: : :.:: .. :. :: :..: .:
NP_004 CSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEADQEPGSQMVEASLSVRHPEYNRPLLAN
60 70 80 90 100 110
160 170 180 190 200 210
pF1KE3 DLMLIKLNRRIRPTKDVRPINVSSHCPSAGTKCLVSGWGTTKSPQVHFPKVLQCLNISVL
:::::::.. . . .: :...:.::.::..::::::: . .. : ::::.:.::.
NP_004 DLMLIKLDESVSESDTIRSISIASQCPTAGNSCLVSGWGLLANGRM--PTVLQCVNVSVV
120 130 140 150 160 170
220 230 240 250 260 270
pF1KE3 SQKRCEDAYPRQIDDTMFCAGD-KAGRDSCQGDSGGPVVCNGSLQGLVSWGDYPCARPNR
:.. : : .::::: . .:::.::::::..::: ::::::.: ::.. .
NP_004 SEEVCSKLYDPLYHPSMFCAGGGQDQKDSCNGDSGGPLICNGYLQGLVSFGKAPCGQVGV
180 190 200 210 220 230
280 290
pF1KE3 PGVYTNLCKFTKWIQETIQANS
:::::::::::.::..:.::.
NP_004 PGVYTNLCKFTEWIEKTVQAS
240 250
293 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 03:29:08 2016 done: Mon Nov 7 03:29:09 2016
Total Scan time: 7.470 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]