Result of FASTA (omim) for
pFN21AE3628
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3628, 180 aa
1>>>pF1KE3628 180 - 180 aa - 180 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.5612+/-0.000342; mu= 11.6764+/- 0.021
mean_var=66.9881+/-13.221, 0's: 0 Z-trim(114.2): 9 B-trim: 0 in 0/54
Lambda= 0.156702
statistics sampled from 23979 (23986) to 23979 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.672), E-opt: 0.2 (0.281), width: 16
Scan time: 4.950
The best scores are: opt bits E(85289)
NP_002045 (OMIM: 138030) glucagon preproprotein [H ( 180) 1196 278.9 3.1e-75
XP_006715625 (OMIM: 192320) PREDICTED: VIP peptide ( 169) 174 47.8 1.1e-05
NP_003372 (OMIM: 192320) VIP peptides isoform 1 pr ( 170) 172 47.4 1.5e-05
XP_005267192 (OMIM: 192320) PREDICTED: VIP peptide ( 168) 163 45.3 5.9e-05
NP_919416 (OMIM: 192320) VIP peptides isoform 2 pr ( 169) 161 44.9 8.1e-05
NP_004114 (OMIM: 137240) gastric inhibitory polype ( 153) 143 40.8 0.0012
>>NP_002045 (OMIM: 138030) glucagon preproprotein [Homo (180 aa)
initn: 1196 init1: 1196 opt: 1196 Z-score: 1471.6 bits: 278.9 E(85289): 3.1e-75
Smith-Waterman score: 1196; 100.0% identity (100.0% similar) in 180 aa overlap (1-180:1-180)
10 20 30 40 50 60
pF1KE3 MKSIYFVAGLFVMLVQGSWQRSLQDTEEKSRSFSASQADPLSDPDQMNEDKRHSQGTFTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MKSIYFVAGLFVMLVQGSWQRSLQDTEEKSRSFSASQADPLSDPDQMNEDKRHSQGTFTS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 DYSKYLDSRRAQDFVQWLMNTKRNRNNIAKRHDEFERHAEGTFTSDVSSYLEGQAAKEFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 DYSKYLDSRRAQDFVQWLMNTKRNRNNIAKRHDEFERHAEGTFTSDVSSYLEGQAAKEFI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 AWLVKGRGRRDFPEEVAIVEELGRRHADGSFSDEMNTILDNLAARDFINWLIQTKITDRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 AWLVKGRGRRDFPEEVAIVEELGRRHADGSFSDEMNTILDNLAARDFINWLIQTKITDRK
130 140 150 160 170 180
>>XP_006715625 (OMIM: 192320) PREDICTED: VIP peptides is (169 aa)
initn: 192 init1: 93 opt: 174 Z-score: 223.4 bits: 47.8 E(85289): 1.1e-05
Smith-Waterman score: 174; 29.8% identity (65.3% similar) in 121 aa overlap (20-136:51-167)
10 20 30 40
pF1KE3 MKSIYFVAGLFVMLVQGSWQRSLQDTEEKSRSFSASQADPLSDPDQMNE
: ::.. . .. : . : : ...
XP_006 SQTSAWPLYRAPSALRLGDRIPFEGANEPDQVSLKEDIDMLQNALAENDTPYYD---VSR
30 40 50 60 70
50 60 70 80 90 100
pF1KE3 DKRHSQGTFTSDYSKYLDSRRAQDFVQWLMNTKRNRNNIAKRHDEFERHAEGTFTSDVSS
. ::..:.::::.:: : . :. ... ::. :: .::.. .::....::.. .
XP_006 NARHADGVFTSDFSKLLGQLSAKKYLESLMG-KRVSSNISEDPVPVKRHSDAVFTDNYTR
80 90 100 110 120 130
110 120 130 140 150 160
pF1KE3 YLEGQAAKEFIAWLVKGR---GRR-DFPEEVAIVEELGRRHADGSFSDEMNTILDNLAAR
. .:.:... ...:. :. :::::.
XP_006 LRKQMAVKKYLNSILNGKRSEGESPDFPEELEK
140 150 160
170 180
pF1KE3 DFINWLIQTKITDRK
>>NP_003372 (OMIM: 192320) VIP peptides isoform 1 prepro (170 aa)
initn: 192 init1: 93 opt: 172 Z-score: 220.9 bits: 47.4 E(85289): 1.5e-05
Smith-Waterman score: 172; 29.5% identity (64.8% similar) in 122 aa overlap (20-136:51-168)
10 20 30 40
pF1KE3 MKSIYFVAGLFVMLVQGSWQRSLQDTEEKSRSFSASQADPLSDPDQMNE
: ::.. . .. : . : : ...
NP_003 SQTSAWPLYRAPSALRLGDRIPFEGANEPDQVSLKEDIDMLQNALAENDTPYYD---VSR
30 40 50 60 70
50 60 70 80 90 100
pF1KE3 DKRHSQGTFTSDYSKYLDSRRAQDFVQWLMNTKRNRNNIAKRHDEFERHAEGTFTSDVSS
. ::..:.::::.:: : . :. ... ::. :: .::.. .::....::.. .
NP_003 NARHADGVFTSDFSKLLGQLSAKKYLESLMG-KRVSSNISEDPVPVKRHSDAVFTDNYTR
80 90 100 110 120 130
110 120 130 140 150 160
pF1KE3 YLEGQAAKEFIAWLVKGR----GRR-DFPEEVAIVEELGRRHADGSFSDEMNTILDNLAA
. .:.:... ...:. :. :::::.
NP_003 LRKQMAVKKYLNSILNGKRSSEGESPDFPEELEK
140 150 160 170
170 180
pF1KE3 RDFINWLIQTKITDRK
>>XP_005267192 (OMIM: 192320) PREDICTED: VIP peptides is (168 aa)
initn: 201 init1: 89 opt: 163 Z-score: 210.0 bits: 45.3 E(85289): 5.9e-05
Smith-Waterman score: 163; 29.8% identity (65.3% similar) in 121 aa overlap (20-136:51-166)
10 20 30 40
pF1KE3 MKSIYFVAGLFVMLVQGSWQRSLQDTEEKSRSFSASQADPLSDPDQMNE
: ::.. . .. : . : : ...
XP_005 SQTSAWPLYRAPSALRLGDRIPFEGANEPDQVSLKEDIDMLQNALAENDTPYYD---VSR
30 40 50 60 70
50 60 70 80 90 100
pF1KE3 DKRHSQGTFTSDYSKYLDSRRAQDFVQWLMNTKRNRNNIAKRHDEFERHAEGTFTSDVSS
. ::..:.::::.:: : . :. ... ::. :: .::.. .::....::.. .
XP_005 NARHADGVFTSDFSKLLGQLSAKKYLESLMG-KRV-SNISEDPVPVKRHSDAVFTDNYTR
80 90 100 110 120 130
110 120 130 140 150 160
pF1KE3 YLEGQAAKEFIAWLVKGR---GRR-DFPEEVAIVEELGRRHADGSFSDEMNTILDNLAAR
. .:.:... ...:. :. :::::.
XP_005 LRKQMAVKKYLNSILNGKRSEGESPDFPEELEK
140 150 160
170 180
pF1KE3 DFINWLIQTKITDRK
>>NP_919416 (OMIM: 192320) VIP peptides isoform 2 prepro (169 aa)
initn: 188 init1: 89 opt: 161 Z-score: 207.5 bits: 44.9 E(85289): 8.1e-05
Smith-Waterman score: 161; 29.5% identity (64.8% similar) in 122 aa overlap (20-136:51-167)
10 20 30 40
pF1KE3 MKSIYFVAGLFVMLVQGSWQRSLQDTEEKSRSFSASQADPLSDPDQMNE
: ::.. . .. : . : : ...
NP_919 SQTSAWPLYRAPSALRLGDRIPFEGANEPDQVSLKEDIDMLQNALAENDTPYYD---VSR
30 40 50 60 70
50 60 70 80 90 100
pF1KE3 DKRHSQGTFTSDYSKYLDSRRAQDFVQWLMNTKRNRNNIAKRHDEFERHAEGTFTSDVSS
. ::..:.::::.:: : . :. ... ::. :: .::.. .::....::.. .
NP_919 NARHADGVFTSDFSKLLGQLSAKKYLESLMG-KRV-SNISEDPVPVKRHSDAVFTDNYTR
80 90 100 110 120 130
110 120 130 140 150 160
pF1KE3 YLEGQAAKEFIAWLVKGR----GRR-DFPEEVAIVEELGRRHADGSFSDEMNTILDNLAA
. .:.:... ...:. :. :::::.
NP_919 LRKQMAVKKYLNSILNGKRSSEGESPDFPEELEK
140 150 160
170 180
pF1KE3 RDFINWLIQTKITDRK
>>NP_004114 (OMIM: 137240) gastric inhibitory polypeptid (153 aa)
initn: 111 init1: 111 opt: 143 Z-score: 186.2 bits: 40.8 E(85289): 0.0012
Smith-Waterman score: 143; 29.5% identity (64.2% similar) in 95 aa overlap (27-117:22-114)
10 20 30 40 50
pF1KE3 MKSIYFVAGLFVMLVQGSWQRSLQDTEEKSRSFSASQADPLSDPDQMNEDK----RHSQG
:.: ::: . :... ... . :...:
NP_004 MVATKTFALLLLSLFLAVGLGEKKEGHFSALPSLPVGSHAKVSSPQPRGPRYAEG
10 20 30 40 50
60 70 80 90 100 110
pF1KE3 TFTSDYSKYLDSRRAQDFVQWLMNTKRNRNNIAKRHDEFERHAEGTFTSDVSSYLEGQAA
:: :::: .:. . ::::.::. : ..:. .:. .:.:.. .. .. : .:.
NP_004 TFISDYSIAMDKIHQQDFVNWLLAQKGKKNDW--KHNITQREARALELASQANRKEEEAV
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE3 KEFIAWLVKGRGRRDFPEEVAIVEELGRRHADGSFSDEMNTILDNLAARDFINWLIQTKI
.
NP_004 EPQSSPAKNPSDEDLLRDLLIQELLACLLDQTNLCRLRSR
120 130 140 150
180 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 02:22:30 2016 done: Mon Nov 7 02:22:30 2016
Total Scan time: 4.950 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]