Result of FASTA (omim) for
pFN21AE3625
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3625, 454 aa
1>>>pF1KE3625 454 - 454 aa - 454 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.3990+/-0.000572; mu= 17.7713+/- 0.035
mean_var=122.8732+/-26.513, 0's: 0 Z-trim(109.5): 350 B-trim: 225 in 2/51
Lambda= 0.115703
statistics sampled from 17273 (17699) to 17273 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.556), E-opt: 0.2 (0.208), width: 16
Scan time: 8.840
The best scores are: opt bits E(85289)
NP_036296 (OMIM: 609071) F-box/WD repeat-containin ( 454) 3081 526.6 5.4e-149
XP_005251967 (OMIM: 609071) PREDICTED: F-box/WD re ( 454) 3081 526.6 5.4e-149
XP_011516820 (OMIM: 609071) PREDICTED: F-box/WD re ( 486) 3081 526.6 5.6e-149
XP_006717112 (OMIM: 609071) PREDICTED: F-box/WD re ( 486) 3081 526.6 5.6e-149
XP_016870105 (OMIM: 609071) PREDICTED: F-box/WD re ( 325) 2215 381.8 1.4e-105
XP_016870106 (OMIM: 609071) PREDICTED: F-box/WD re ( 325) 2215 381.8 1.4e-105
XP_005251970 (OMIM: 609071) PREDICTED: F-box/WD re ( 325) 2215 381.8 1.4e-105
XP_016870104 (OMIM: 609071) PREDICTED: F-box/WD re ( 389) 1532 267.9 3.4e-71
XP_006717114 (OMIM: 609071) PREDICTED: F-box/WD re ( 421) 1532 268.0 3.5e-71
XP_011530390 (OMIM: 606278) PREDICTED: F-box/WD re ( 540) 306 63.4 1.7e-09
NP_001013433 (OMIM: 606278) F-box/WD repeat-contai ( 589) 306 63.5 1.8e-09
NP_060785 (OMIM: 606278) F-box/WD repeat-containin ( 627) 306 63.5 1.8e-09
XP_011530389 (OMIM: 606278) PREDICTED: F-box/WD re ( 679) 306 63.6 1.9e-09
XP_011530388 (OMIM: 606278) PREDICTED: F-box/WD re ( 679) 306 63.6 1.9e-09
NP_361014 (OMIM: 606278) F-box/WD repeat-containin ( 707) 306 63.6 2e-09
XP_011530387 (OMIM: 606278) PREDICTED: F-box/WD re ( 707) 306 63.6 2e-09
XP_016863851 (OMIM: 606278) PREDICTED: F-box/WD re ( 707) 306 63.6 2e-09
XP_011530385 (OMIM: 606278) PREDICTED: F-box/WD re ( 707) 306 63.6 2e-09
XP_011530386 (OMIM: 606278) PREDICTED: F-box/WD re ( 707) 306 63.6 2e-09
NP_060058 (OMIM: 609012) WD repeat-containing prot ( 334) 247 53.3 1.1e-06
NP_438172 (OMIM: 609012) WD repeat-containing prot ( 334) 247 53.3 1.1e-06
XP_005272220 (OMIM: 609012) PREDICTED: WD repeat-c ( 334) 247 53.3 1.1e-06
XP_016880191 (OMIM: 601545,607432) PREDICTED: plat ( 345) 242 52.5 2.1e-06
NP_000421 (OMIM: 601545,607432) platelet-activatin ( 410) 242 52.6 2.3e-06
XP_016880190 (OMIM: 601545,607432) PREDICTED: plat ( 410) 242 52.6 2.3e-06
XP_016880189 (OMIM: 601545,607432) PREDICTED: plat ( 410) 242 52.6 2.3e-06
XP_016880188 (OMIM: 601545,607432) PREDICTED: plat ( 410) 242 52.6 2.3e-06
XP_011522203 (OMIM: 601545,607432) PREDICTED: plat ( 428) 242 52.6 2.4e-06
XP_011522204 (OMIM: 601545,607432) PREDICTED: plat ( 428) 242 52.6 2.4e-06
XP_011522205 (OMIM: 601545,607432) PREDICTED: plat ( 428) 242 52.6 2.4e-06
NP_001188493 (OMIM: 605961) pleiotropic regulator ( 505) 237 51.9 4.7e-06
NP_002660 (OMIM: 605961) pleiotropic regulator 1 i ( 514) 237 51.9 4.7e-06
NP_115708 (OMIM: 616850) WD repeat domain-containi ( 315) 216 48.1 4e-05
NP_001093207 (OMIM: 616850) WD repeat domain-conta ( 315) 216 48.1 4e-05
NP_006089 (OMIM: 176981) receptor of activated pro ( 317) 216 48.1 4e-05
NP_001269467 (OMIM: 139380,613065,616973) guanine ( 240) 204 46.0 0.00013
NP_001151 (OMIM: 602233) apoptotic protease-activa (1194) 211 48.0 0.00016
NP_863658 (OMIM: 602233) apoptotic protease-activa (1205) 211 48.0 0.00016
NP_037361 (OMIM: 602233) apoptotic protease-activa (1237) 211 48.0 0.00017
XP_016856548 (OMIM: 139380,613065,616973) PREDICTE ( 340) 204 46.2 0.00017
XP_016856550 (OMIM: 139380,613065,616973) PREDICTE ( 340) 204 46.2 0.00017
NP_002065 (OMIM: 139380,613065,616973) guanine nuc ( 340) 204 46.2 0.00017
XP_016856549 (OMIM: 139380,613065,616973) PREDICTE ( 340) 204 46.2 0.00017
NP_001269468 (OMIM: 139380,613065,616973) guanine ( 340) 204 46.2 0.00017
NP_863651 (OMIM: 602233) apoptotic protease-activa (1248) 211 48.0 0.00017
XP_011516374 (OMIM: 603873) PREDICTED: phospholipa ( 524) 206 46.7 0.00017
XP_016870808 (OMIM: 603873) PREDICTED: phospholipa ( 534) 206 46.7 0.00017
NP_001308475 (OMIM: 603873) phospholipase A-2-acti ( 772) 206 46.9 0.00022
NP_001026859 (OMIM: 603873) phospholipase A-2-acti ( 795) 206 47.0 0.00022
NP_001309196 (OMIM: 607795,615922) U4/U6 small nuc ( 279) 200 45.4 0.00023
>>NP_036296 (OMIM: 609071) F-box/WD repeat-containing pr (454 aa)
initn: 3081 init1: 3081 opt: 3081 Z-score: 2795.9 bits: 526.6 E(85289): 5.4e-149
Smith-Waterman score: 3081; 100.0% identity (100.0% similar) in 454 aa overlap (1-454:1-454)
10 20 30 40 50 60
pF1KE3 MERKDFETWLDNISVTFLSLTDLQKNETLDHLISLSGAVQLRHLSNNLETLLKRDFLKLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 MERKDFETWLDNISVTFLSLTDLQKNETLDHLISLSGAVQLRHLSNNLETLLKRDFLKLL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 PLELSFYLLKWLDPQTLLTCCLVSKQWNKVISACTEVWQTACKNLGWQIDDSVQDALHWK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 PLELSFYLLKWLDPQTLLTCCLVSKQWNKVISACTEVWQTACKNLGWQIDDSVQDALHWK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 KVYLKAILRMKQLEDHEAFETSSLIGHSARVYALYYKDGLLCTGSDDLSAKLWDVSTGQC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 KVYLKAILRMKQLEDHEAFETSSLIGHSARVYALYYKDGLLCTGSDDLSAKLWDVSTGQC
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 VYGIQTHTCAAVKFDEQKLVTGSFDNTVACWEWSSGARTQHFRGHTGAVFSVDYNDELDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 VYGIQTHTCAAVKFDEQKLVTGSFDNTVACWEWSSGARTQHFRGHTGAVFSVDYNDELDI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 LVSGSADFTVKVWALSAGTCLNTLTGHTEWVTKVVLQKCKVKSLLHSPGDYILLSADKYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 LVSGSADFTVKVWALSAGTCLNTLTGHTEWVTKVVLQKCKVKSLLHSPGDYILLSADKYE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 IKIWPIGREINCKCLKTLSVSEDRSICLQPRLHFDGKYIVCSSALGLYQWDFASYDILRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 IKIWPIGREINCKCLKTLSVSEDRSICLQPRLHFDGKYIVCSSALGLYQWDFASYDILRV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 IKTPEIANLALLGFGDIFALLFDNRYLYIMDLRTESLISRWPLPEYRKSKRGSSFLAGEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 IKTPEIANLALLGFGDIFALLFDNRYLYIMDLRTESLISRWPLPEYRKSKRGSSFLAGEA
370 380 390 400 410 420
430 440 450
pF1KE3 SWLNGLDGHNDTGLVFATSMPDHSIHLVLWKEHG
::::::::::::::::::::::::::::::::::
NP_036 SWLNGLDGHNDTGLVFATSMPDHSIHLVLWKEHG
430 440 450
>>XP_005251967 (OMIM: 609071) PREDICTED: F-box/WD repeat (454 aa)
initn: 3081 init1: 3081 opt: 3081 Z-score: 2795.9 bits: 526.6 E(85289): 5.4e-149
Smith-Waterman score: 3081; 100.0% identity (100.0% similar) in 454 aa overlap (1-454:1-454)
10 20 30 40 50 60
pF1KE3 MERKDFETWLDNISVTFLSLTDLQKNETLDHLISLSGAVQLRHLSNNLETLLKRDFLKLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MERKDFETWLDNISVTFLSLTDLQKNETLDHLISLSGAVQLRHLSNNLETLLKRDFLKLL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 PLELSFYLLKWLDPQTLLTCCLVSKQWNKVISACTEVWQTACKNLGWQIDDSVQDALHWK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PLELSFYLLKWLDPQTLLTCCLVSKQWNKVISACTEVWQTACKNLGWQIDDSVQDALHWK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 KVYLKAILRMKQLEDHEAFETSSLIGHSARVYALYYKDGLLCTGSDDLSAKLWDVSTGQC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KVYLKAILRMKQLEDHEAFETSSLIGHSARVYALYYKDGLLCTGSDDLSAKLWDVSTGQC
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 VYGIQTHTCAAVKFDEQKLVTGSFDNTVACWEWSSGARTQHFRGHTGAVFSVDYNDELDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VYGIQTHTCAAVKFDEQKLVTGSFDNTVACWEWSSGARTQHFRGHTGAVFSVDYNDELDI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 LVSGSADFTVKVWALSAGTCLNTLTGHTEWVTKVVLQKCKVKSLLHSPGDYILLSADKYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LVSGSADFTVKVWALSAGTCLNTLTGHTEWVTKVVLQKCKVKSLLHSPGDYILLSADKYE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 IKIWPIGREINCKCLKTLSVSEDRSICLQPRLHFDGKYIVCSSALGLYQWDFASYDILRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IKIWPIGREINCKCLKTLSVSEDRSICLQPRLHFDGKYIVCSSALGLYQWDFASYDILRV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 IKTPEIANLALLGFGDIFALLFDNRYLYIMDLRTESLISRWPLPEYRKSKRGSSFLAGEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IKTPEIANLALLGFGDIFALLFDNRYLYIMDLRTESLISRWPLPEYRKSKRGSSFLAGEA
370 380 390 400 410 420
430 440 450
pF1KE3 SWLNGLDGHNDTGLVFATSMPDHSIHLVLWKEHG
::::::::::::::::::::::::::::::::::
XP_005 SWLNGLDGHNDTGLVFATSMPDHSIHLVLWKEHG
430 440 450
>>XP_011516820 (OMIM: 609071) PREDICTED: F-box/WD repeat (486 aa)
initn: 3081 init1: 3081 opt: 3081 Z-score: 2795.6 bits: 526.6 E(85289): 5.6e-149
Smith-Waterman score: 3081; 100.0% identity (100.0% similar) in 454 aa overlap (1-454:33-486)
10 20 30
pF1KE3 MERKDFETWLDNISVTFLSLTDLQKNETLD
::::::::::::::::::::::::::::::
XP_011 CDEVVYEVQSAILRHNCGYAMKTGKFFHNLMERKDFETWLDNISVTFLSLTDLQKNETLD
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE3 HLISLSGAVQLRHLSNNLETLLKRDFLKLLPLELSFYLLKWLDPQTLLTCCLVSKQWNKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HLISLSGAVQLRHLSNNLETLLKRDFLKLLPLELSFYLLKWLDPQTLLTCCLVSKQWNKV
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE3 ISACTEVWQTACKNLGWQIDDSVQDALHWKKVYLKAILRMKQLEDHEAFETSSLIGHSAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ISACTEVWQTACKNLGWQIDDSVQDALHWKKVYLKAILRMKQLEDHEAFETSSLIGHSAR
130 140 150 160 170 180
160 170 180 190 200 210
pF1KE3 VYALYYKDGLLCTGSDDLSAKLWDVSTGQCVYGIQTHTCAAVKFDEQKLVTGSFDNTVAC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VYALYYKDGLLCTGSDDLSAKLWDVSTGQCVYGIQTHTCAAVKFDEQKLVTGSFDNTVAC
190 200 210 220 230 240
220 230 240 250 260 270
pF1KE3 WEWSSGARTQHFRGHTGAVFSVDYNDELDILVSGSADFTVKVWALSAGTCLNTLTGHTEW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WEWSSGARTQHFRGHTGAVFSVDYNDELDILVSGSADFTVKVWALSAGTCLNTLTGHTEW
250 260 270 280 290 300
280 290 300 310 320 330
pF1KE3 VTKVVLQKCKVKSLLHSPGDYILLSADKYEIKIWPIGREINCKCLKTLSVSEDRSICLQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VTKVVLQKCKVKSLLHSPGDYILLSADKYEIKIWPIGREINCKCLKTLSVSEDRSICLQP
310 320 330 340 350 360
340 350 360 370 380 390
pF1KE3 RLHFDGKYIVCSSALGLYQWDFASYDILRVIKTPEIANLALLGFGDIFALLFDNRYLYIM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RLHFDGKYIVCSSALGLYQWDFASYDILRVIKTPEIANLALLGFGDIFALLFDNRYLYIM
370 380 390 400 410 420
400 410 420 430 440 450
pF1KE3 DLRTESLISRWPLPEYRKSKRGSSFLAGEASWLNGLDGHNDTGLVFATSMPDHSIHLVLW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLRTESLISRWPLPEYRKSKRGSSFLAGEASWLNGLDGHNDTGLVFATSMPDHSIHLVLW
430 440 450 460 470 480
pF1KE3 KEHG
::::
XP_011 KEHG
>>XP_006717112 (OMIM: 609071) PREDICTED: F-box/WD repeat (486 aa)
initn: 3081 init1: 3081 opt: 3081 Z-score: 2795.6 bits: 526.6 E(85289): 5.6e-149
Smith-Waterman score: 3081; 100.0% identity (100.0% similar) in 454 aa overlap (1-454:33-486)
10 20 30
pF1KE3 MERKDFETWLDNISVTFLSLTDLQKNETLD
::::::::::::::::::::::::::::::
XP_006 CDEVVYEVQSAILRHNCGYAMKTGKFFHNLMERKDFETWLDNISVTFLSLTDLQKNETLD
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE3 HLISLSGAVQLRHLSNNLETLLKRDFLKLLPLELSFYLLKWLDPQTLLTCCLVSKQWNKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HLISLSGAVQLRHLSNNLETLLKRDFLKLLPLELSFYLLKWLDPQTLLTCCLVSKQWNKV
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE3 ISACTEVWQTACKNLGWQIDDSVQDALHWKKVYLKAILRMKQLEDHEAFETSSLIGHSAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ISACTEVWQTACKNLGWQIDDSVQDALHWKKVYLKAILRMKQLEDHEAFETSSLIGHSAR
130 140 150 160 170 180
160 170 180 190 200 210
pF1KE3 VYALYYKDGLLCTGSDDLSAKLWDVSTGQCVYGIQTHTCAAVKFDEQKLVTGSFDNTVAC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VYALYYKDGLLCTGSDDLSAKLWDVSTGQCVYGIQTHTCAAVKFDEQKLVTGSFDNTVAC
190 200 210 220 230 240
220 230 240 250 260 270
pF1KE3 WEWSSGARTQHFRGHTGAVFSVDYNDELDILVSGSADFTVKVWALSAGTCLNTLTGHTEW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 WEWSSGARTQHFRGHTGAVFSVDYNDELDILVSGSADFTVKVWALSAGTCLNTLTGHTEW
250 260 270 280 290 300
280 290 300 310 320 330
pF1KE3 VTKVVLQKCKVKSLLHSPGDYILLSADKYEIKIWPIGREINCKCLKTLSVSEDRSICLQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VTKVVLQKCKVKSLLHSPGDYILLSADKYEIKIWPIGREINCKCLKTLSVSEDRSICLQP
310 320 330 340 350 360
340 350 360 370 380 390
pF1KE3 RLHFDGKYIVCSSALGLYQWDFASYDILRVIKTPEIANLALLGFGDIFALLFDNRYLYIM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RLHFDGKYIVCSSALGLYQWDFASYDILRVIKTPEIANLALLGFGDIFALLFDNRYLYIM
370 380 390 400 410 420
400 410 420 430 440 450
pF1KE3 DLRTESLISRWPLPEYRKSKRGSSFLAGEASWLNGLDGHNDTGLVFATSMPDHSIHLVLW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DLRTESLISRWPLPEYRKSKRGSSFLAGEASWLNGLDGHNDTGLVFATSMPDHSIHLVLW
430 440 450 460 470 480
pF1KE3 KEHG
::::
XP_006 KEHG
>>XP_016870105 (OMIM: 609071) PREDICTED: F-box/WD repeat (325 aa)
initn: 2215 init1: 2215 opt: 2215 Z-score: 2016.3 bits: 381.8 E(85289): 1.4e-105
Smith-Waterman score: 2215; 100.0% identity (100.0% similar) in 325 aa overlap (130-454:1-325)
100 110 120 130 140 150
pF1KE3 TACKNLGWQIDDSVQDALHWKKVYLKAILRMKQLEDHEAFETSSLIGHSARVYALYYKDG
::::::::::::::::::::::::::::::
XP_016 MKQLEDHEAFETSSLIGHSARVYALYYKDG
10 20 30
160 170 180 190 200 210
pF1KE3 LLCTGSDDLSAKLWDVSTGQCVYGIQTHTCAAVKFDEQKLVTGSFDNTVACWEWSSGART
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLCTGSDDLSAKLWDVSTGQCVYGIQTHTCAAVKFDEQKLVTGSFDNTVACWEWSSGART
40 50 60 70 80 90
220 230 240 250 260 270
pF1KE3 QHFRGHTGAVFSVDYNDELDILVSGSADFTVKVWALSAGTCLNTLTGHTEWVTKVVLQKC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QHFRGHTGAVFSVDYNDELDILVSGSADFTVKVWALSAGTCLNTLTGHTEWVTKVVLQKC
100 110 120 130 140 150
280 290 300 310 320 330
pF1KE3 KVKSLLHSPGDYILLSADKYEIKIWPIGREINCKCLKTLSVSEDRSICLQPRLHFDGKYI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KVKSLLHSPGDYILLSADKYEIKIWPIGREINCKCLKTLSVSEDRSICLQPRLHFDGKYI
160 170 180 190 200 210
340 350 360 370 380 390
pF1KE3 VCSSALGLYQWDFASYDILRVIKTPEIANLALLGFGDIFALLFDNRYLYIMDLRTESLIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VCSSALGLYQWDFASYDILRVIKTPEIANLALLGFGDIFALLFDNRYLYIMDLRTESLIS
220 230 240 250 260 270
400 410 420 430 440 450
pF1KE3 RWPLPEYRKSKRGSSFLAGEASWLNGLDGHNDTGLVFATSMPDHSIHLVLWKEHG
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RWPLPEYRKSKRGSSFLAGEASWLNGLDGHNDTGLVFATSMPDHSIHLVLWKEHG
280 290 300 310 320
>>XP_016870106 (OMIM: 609071) PREDICTED: F-box/WD repeat (325 aa)
initn: 2215 init1: 2215 opt: 2215 Z-score: 2016.3 bits: 381.8 E(85289): 1.4e-105
Smith-Waterman score: 2215; 100.0% identity (100.0% similar) in 325 aa overlap (130-454:1-325)
100 110 120 130 140 150
pF1KE3 TACKNLGWQIDDSVQDALHWKKVYLKAILRMKQLEDHEAFETSSLIGHSARVYALYYKDG
::::::::::::::::::::::::::::::
XP_016 MKQLEDHEAFETSSLIGHSARVYALYYKDG
10 20 30
160 170 180 190 200 210
pF1KE3 LLCTGSDDLSAKLWDVSTGQCVYGIQTHTCAAVKFDEQKLVTGSFDNTVACWEWSSGART
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLCTGSDDLSAKLWDVSTGQCVYGIQTHTCAAVKFDEQKLVTGSFDNTVACWEWSSGART
40 50 60 70 80 90
220 230 240 250 260 270
pF1KE3 QHFRGHTGAVFSVDYNDELDILVSGSADFTVKVWALSAGTCLNTLTGHTEWVTKVVLQKC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QHFRGHTGAVFSVDYNDELDILVSGSADFTVKVWALSAGTCLNTLTGHTEWVTKVVLQKC
100 110 120 130 140 150
280 290 300 310 320 330
pF1KE3 KVKSLLHSPGDYILLSADKYEIKIWPIGREINCKCLKTLSVSEDRSICLQPRLHFDGKYI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KVKSLLHSPGDYILLSADKYEIKIWPIGREINCKCLKTLSVSEDRSICLQPRLHFDGKYI
160 170 180 190 200 210
340 350 360 370 380 390
pF1KE3 VCSSALGLYQWDFASYDILRVIKTPEIANLALLGFGDIFALLFDNRYLYIMDLRTESLIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VCSSALGLYQWDFASYDILRVIKTPEIANLALLGFGDIFALLFDNRYLYIMDLRTESLIS
220 230 240 250 260 270
400 410 420 430 440 450
pF1KE3 RWPLPEYRKSKRGSSFLAGEASWLNGLDGHNDTGLVFATSMPDHSIHLVLWKEHG
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RWPLPEYRKSKRGSSFLAGEASWLNGLDGHNDTGLVFATSMPDHSIHLVLWKEHG
280 290 300 310 320
>>XP_005251970 (OMIM: 609071) PREDICTED: F-box/WD repeat (325 aa)
initn: 2215 init1: 2215 opt: 2215 Z-score: 2016.3 bits: 381.8 E(85289): 1.4e-105
Smith-Waterman score: 2215; 100.0% identity (100.0% similar) in 325 aa overlap (130-454:1-325)
100 110 120 130 140 150
pF1KE3 TACKNLGWQIDDSVQDALHWKKVYLKAILRMKQLEDHEAFETSSLIGHSARVYALYYKDG
::::::::::::::::::::::::::::::
XP_005 MKQLEDHEAFETSSLIGHSARVYALYYKDG
10 20 30
160 170 180 190 200 210
pF1KE3 LLCTGSDDLSAKLWDVSTGQCVYGIQTHTCAAVKFDEQKLVTGSFDNTVACWEWSSGART
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LLCTGSDDLSAKLWDVSTGQCVYGIQTHTCAAVKFDEQKLVTGSFDNTVACWEWSSGART
40 50 60 70 80 90
220 230 240 250 260 270
pF1KE3 QHFRGHTGAVFSVDYNDELDILVSGSADFTVKVWALSAGTCLNTLTGHTEWVTKVVLQKC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QHFRGHTGAVFSVDYNDELDILVSGSADFTVKVWALSAGTCLNTLTGHTEWVTKVVLQKC
100 110 120 130 140 150
280 290 300 310 320 330
pF1KE3 KVKSLLHSPGDYILLSADKYEIKIWPIGREINCKCLKTLSVSEDRSICLQPRLHFDGKYI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KVKSLLHSPGDYILLSADKYEIKIWPIGREINCKCLKTLSVSEDRSICLQPRLHFDGKYI
160 170 180 190 200 210
340 350 360 370 380 390
pF1KE3 VCSSALGLYQWDFASYDILRVIKTPEIANLALLGFGDIFALLFDNRYLYIMDLRTESLIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VCSSALGLYQWDFASYDILRVIKTPEIANLALLGFGDIFALLFDNRYLYIMDLRTESLIS
220 230 240 250 260 270
400 410 420 430 440 450
pF1KE3 RWPLPEYRKSKRGSSFLAGEASWLNGLDGHNDTGLVFATSMPDHSIHLVLWKEHG
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RWPLPEYRKSKRGSSFLAGEASWLNGLDGHNDTGLVFATSMPDHSIHLVLWKEHG
280 290 300 310 320
>>XP_016870104 (OMIM: 609071) PREDICTED: F-box/WD repeat (389 aa)
initn: 2606 init1: 1531 opt: 1532 Z-score: 1399.3 bits: 267.9 E(85289): 3.4e-71
Smith-Waterman score: 2480; 85.7% identity (85.7% similar) in 454 aa overlap (1-454:1-389)
10 20 30 40 50 60
pF1KE3 MERKDFETWLDNISVTFLSLTDLQKNETLDHLISLSGAVQLRHLSNNLETLLKRDFLKLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MERKDFETWLDNISVTFLSLTDLQKNETLDHLISLSGAVQLRHLSNNLETLLKRDFLKLL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 PLELSFYLLKWLDPQTLLTCCLVSKQWNKVISACTEVWQTACKNLGWQIDDSVQDALHWK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PLELSFYLLKWLDPQTLLTCCLVSKQWNKVISACTEVWQTACKNLGWQIDDSVQDALHWK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 KVYLKAILRMKQLEDHEAFETSSLIGHSARVYALYYKDGLLCTGSDDLSAKLWDVSTGQC
:::::::::::::::::::::::::::::::::::::::::::
XP_016 KVYLKAILRMKQLEDHEAFETSSLIGHSARVYALYYKDGLLCT-----------------
130 140 150 160
190 200 210 220 230 240
pF1KE3 VYGIQTHTCAAVKFDEQKLVTGSFDNTVACWEWSSGARTQHFRGHTGAVFSVDYNDELDI
::::::::::::
XP_016 ------------------------------------------------VFSVDYNDELDI
170
250 260 270 280 290 300
pF1KE3 LVSGSADFTVKVWALSAGTCLNTLTGHTEWVTKVVLQKCKVKSLLHSPGDYILLSADKYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LVSGSADFTVKVWALSAGTCLNTLTGHTEWVTKVVLQKCKVKSLLHSPGDYILLSADKYE
180 190 200 210 220 230
310 320 330 340 350 360
pF1KE3 IKIWPIGREINCKCLKTLSVSEDRSICLQPRLHFDGKYIVCSSALGLYQWDFASYDILRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IKIWPIGREINCKCLKTLSVSEDRSICLQPRLHFDGKYIVCSSALGLYQWDFASYDILRV
240 250 260 270 280 290
370 380 390 400 410 420
pF1KE3 IKTPEIANLALLGFGDIFALLFDNRYLYIMDLRTESLISRWPLPEYRKSKRGSSFLAGEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IKTPEIANLALLGFGDIFALLFDNRYLYIMDLRTESLISRWPLPEYRKSKRGSSFLAGEA
300 310 320 330 340 350
430 440 450
pF1KE3 SWLNGLDGHNDTGLVFATSMPDHSIHLVLWKEHG
::::::::::::::::::::::::::::::::::
XP_016 SWLNGLDGHNDTGLVFATSMPDHSIHLVLWKEHG
360 370 380
>>XP_006717114 (OMIM: 609071) PREDICTED: F-box/WD repeat (421 aa)
initn: 2606 init1: 1531 opt: 1532 Z-score: 1398.9 bits: 268.0 E(85289): 3.5e-71
Smith-Waterman score: 2480; 85.7% identity (85.7% similar) in 454 aa overlap (1-454:33-421)
10 20 30
pF1KE3 MERKDFETWLDNISVTFLSLTDLQKNETLD
::::::::::::::::::::::::::::::
XP_006 CDEVVYEVQSAILRHNCGYAMKTGKFFHNLMERKDFETWLDNISVTFLSLTDLQKNETLD
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE3 HLISLSGAVQLRHLSNNLETLLKRDFLKLLPLELSFYLLKWLDPQTLLTCCLVSKQWNKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HLISLSGAVQLRHLSNNLETLLKRDFLKLLPLELSFYLLKWLDPQTLLTCCLVSKQWNKV
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE3 ISACTEVWQTACKNLGWQIDDSVQDALHWKKVYLKAILRMKQLEDHEAFETSSLIGHSAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ISACTEVWQTACKNLGWQIDDSVQDALHWKKVYLKAILRMKQLEDHEAFETSSLIGHSAR
130 140 150 160 170 180
160 170 180 190 200 210
pF1KE3 VYALYYKDGLLCTGSDDLSAKLWDVSTGQCVYGIQTHTCAAVKFDEQKLVTGSFDNTVAC
:::::::::::::
XP_006 VYALYYKDGLLCT-----------------------------------------------
190
220 230 240 250 260 270
pF1KE3 WEWSSGARTQHFRGHTGAVFSVDYNDELDILVSGSADFTVKVWALSAGTCLNTLTGHTEW
::::::::::::::::::::::::::::::::::::::::::
XP_006 ------------------VFSVDYNDELDILVSGSADFTVKVWALSAGTCLNTLTGHTEW
200 210 220 230
280 290 300 310 320 330
pF1KE3 VTKVVLQKCKVKSLLHSPGDYILLSADKYEIKIWPIGREINCKCLKTLSVSEDRSICLQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VTKVVLQKCKVKSLLHSPGDYILLSADKYEIKIWPIGREINCKCLKTLSVSEDRSICLQP
240 250 260 270 280 290
340 350 360 370 380 390
pF1KE3 RLHFDGKYIVCSSALGLYQWDFASYDILRVIKTPEIANLALLGFGDIFALLFDNRYLYIM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RLHFDGKYIVCSSALGLYQWDFASYDILRVIKTPEIANLALLGFGDIFALLFDNRYLYIM
300 310 320 330 340 350
400 410 420 430 440 450
pF1KE3 DLRTESLISRWPLPEYRKSKRGSSFLAGEASWLNGLDGHNDTGLVFATSMPDHSIHLVLW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DLRTESLISRWPLPEYRKSKRGSSFLAGEASWLNGLDGHNDTGLVFATSMPDHSIHLVLW
360 370 380 390 400 410
pF1KE3 KEHG
::::
XP_006 KEHG
420
>>XP_011530390 (OMIM: 606278) PREDICTED: F-box/WD repeat (540 aa)
initn: 616 init1: 179 opt: 306 Z-score: 291.6 bits: 63.4 E(85289): 1.7e-09
Smith-Waterman score: 381; 26.4% identity (55.7% similar) in 318 aa overlap (59-361:116-410)
30 40 50 60 70 80
pF1KE3 LDHLISLSGAVQLRHLSNNLETLLKRDFLKLLPLELSFYLLKWLDPQTLLTCCLVSKQWN
::: ::..:.:..:.:. :: . . :
XP_011 LDELIDSCEPTQVKHMMQVIEPQFQRDFISLLPKELALYVLSFLEPKDLLQAAQTCRYW-
90 100 110 120 130 140
90 100 110 120 130
pF1KE3 KVISACTEVWQTACKNLGWQIDDSVQ---------DALH--WKKVYLKAILRMKQLEDHE
.... . .:. ::. : ::. .. .: ::..:.. . . :
XP_011 RILAEDNLLWREKCKEEG--IDEPLHIKRRKVIKPGFIHSPWKSAYIRQHRIDTNWRRGE
150 160 170 180 190 200
140 150 160 170 180 190
pF1KE3 AFETSSLIGHSARVYA-LYYKDGLLCTGSDDLSAKLWDVSTGQCVYGIQTHTCA--AVKF
. : ::. .: . : . . . .:::: . :.:.. ::.:. . :: . . ..
XP_011 LKSPKVLKGHDDHVITCLQFCGNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQM
210 220 230 240 250 260
200 210 220 230 240 250
pF1KE3 DEQKLVTGSFDNTVACWEWSSGARTQHFRGHTGAVFSVDYNDELDILVSGSADFTVKVWA
.. ...:: : :. :. .: . . :::..: . ... .:::: : :..::
XP_011 RDNIIISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHLHEKR--VVSGSRDATLRVWD
270 280 290 300 310 320
260 270 280 290 300 310
pF1KE3 LSAGTCLNTLTGHTEWVTKVVLQKCKVKSLLHSPGDYILLSADKYEIKIWPIGREINCKC
. .: ::..: ::. : .: .. : .. .: . .:.: : :
XP_011 IETGQCLHVLMGHVAAV------RC-----VQYDGRRVVSGAYDFMVKVWDPETET---C
330 340 350 360
320 330 340 350 360 370
pF1KE3 LKTLSVSEDRSICLQPRLHFDGKYIVCSSA-LGLYQWDFASYDILRVIKTPEIANLALLG
:.::. .: :: ::: ..: .: .. :: . . ....
XP_011 LHTLQGHTNRVYSLQ----FDGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMEL
370 380 390 400 410 420
380 390 400 410 420 430
pF1KE3 FGDIFALLFDNRYLYIMDLRTESLISRWPLPEYRKSKRGSSFLAGEASWLNGLDGHNDTG
XP_011 KDNILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNKNFVITSSDDGTVKLW
430 440 450 460 470 480
454 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 22:45:58 2016 done: Sun Nov 6 22:45:59 2016
Total Scan time: 8.840 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]