Result of FASTA (omim) for
pFN21AE3610
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3610, 364 aa
1>>>pF1KE3610 364 - 364 aa - 364 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.2118+/-0.000349; mu= 16.4876+/- 0.022
mean_var=60.2327+/-11.806, 0's: 0 Z-trim(113.7): 64 B-trim: 1136 in 1/54
Lambda= 0.165256
statistics sampled from 23042 (23109) to 23042 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.65), E-opt: 0.2 (0.271), width: 16
Scan time: 7.900
The best scores are: opt bits E(85289)
NP_065685 (OMIM: 606522,613702,613703,613704) grow ( 364) 2512 607.4 1.6e-173
NP_001483 (OMIM: 187500,208530,217095,602880,61385 ( 372) 524 133.4 8e-31
NP_001191 (OMIM: 112261,112600,235200) bone morpho ( 396) 522 132.9 1.2e-30
XP_011527625 (OMIM: 112261,112600,235200) PREDICTE ( 240) 502 128.1 2.1e-29
XP_016877093 (OMIM: 112262,600625,607932) PREDICTE ( 345) 460 118.1 2.9e-26
XP_016877094 (OMIM: 112262,600625,607932) PREDICTE ( 345) 460 118.1 2.9e-26
NP_570911 (OMIM: 112262,600625,607932) bone morpho ( 408) 460 118.2 3.4e-26
NP_001193 (OMIM: 112262,600625,607932) bone morpho ( 408) 460 118.2 3.4e-26
XP_005268072 (OMIM: 112262,600625,607932) PREDICTE ( 408) 460 118.2 3.4e-26
XP_016877092 (OMIM: 112262,600625,607932) PREDICTE ( 408) 460 118.2 3.4e-26
NP_001709 (OMIM: 112266) bone morphogenetic protei ( 513) 444 114.4 5.8e-25
XP_016866687 (OMIM: 112265) PREDICTED: bone morpho ( 239) 421 108.8 1.3e-23
NP_001710 (OMIM: 112267) bone morphogenetic protei ( 431) 423 109.4 1.6e-23
NP_001711 (OMIM: 602284) bone morphogenetic protei ( 402) 421 108.9 2.1e-23
XP_011540326 (OMIM: 602284) PREDICTED: bone morpho ( 427) 421 108.9 2.2e-23
NP_066551 (OMIM: 112265) bone morphogenetic protei ( 454) 421 108.9 2.3e-23
XP_011527377 (OMIM: 112600,113100,200700,201250,22 ( 501) 410 106.3 1.6e-22
NP_000548 (OMIM: 112600,113100,200700,201250,22890 ( 501) 410 106.3 1.6e-22
NP_001306067 (OMIM: 112600,113100,200700,201250,22 ( 501) 410 106.3 1.6e-22
NP_001001557 (OMIM: 118100,601147,613094,613703,61 ( 455) 384 100.1 1.1e-20
NP_002183 (OMIM: 147290) inhibin beta A chain prep ( 426) 380 99.1 1.9e-20
XP_016867665 (OMIM: 147290) PREDICTED: inhibin bet ( 426) 380 99.1 1.9e-20
XP_016867664 (OMIM: 147290) PREDICTED: inhibin bet ( 483) 380 99.1 2.2e-20
XP_016867663 (OMIM: 147290) PREDICTED: inhibin bet ( 548) 380 99.2 2.4e-20
NP_878248 (OMIM: 604651) growth/differentiation fa ( 450) 367 96.0 1.7e-19
NP_002184 (OMIM: 147390) inhibin beta B chain prep ( 407) 351 92.2 2.3e-18
NP_001192 (OMIM: 112263) bone morphogenetic protei ( 472) 350 92.0 3e-18
NP_001316835 (OMIM: 270100,601265) nodal homolog i ( 214) 334 88.0 2.1e-17
NP_004953 (OMIM: 601361) growth/differentiation fa ( 478) 338 89.1 2.2e-17
NP_060525 (OMIM: 270100,601265) nodal homolog isof ( 347) 334 88.1 3.3e-17
NP_057288 (OMIM: 605120,615506) growth/differentia ( 429) 333 87.9 4.6e-17
NP_055297 (OMIM: 608748) bone morphogenetic protei ( 424) 325 86.0 1.7e-16
NP_005439 (OMIM: 300247,300510) bone morphogenetic ( 392) 316 83.8 7.1e-16
NP_113667 (OMIM: 612031) inhibin beta E chain prep ( 350) 305 81.2 4e-15
NP_005529 (OMIM: 601233) inhibin beta C chain prep ( 352) 298 79.5 1.3e-14
NP_005250 (OMIM: 601788,614160) growth/differentia ( 375) 289 77.4 5.9e-14
XP_011541613 (OMIM: 601918) PREDICTED: growth/diff ( 276) 273 73.5 6.4e-13
NP_001275754 (OMIM: 601918) growth/differentiation ( 366) 273 73.6 8.1e-13
XP_011541612 (OMIM: 601918) PREDICTED: growth/diff ( 366) 273 73.6 8.1e-13
NP_001275757 (OMIM: 601918) growth/differentiation ( 366) 273 73.6 8.1e-13
NP_001275756 (OMIM: 601918) growth/differentiation ( 366) 273 73.6 8.1e-13
NP_001275755 (OMIM: 601918) growth/differentiation ( 366) 273 73.6 8.1e-13
XP_006714648 (OMIM: 601918) PREDICTED: growth/diff ( 366) 273 73.6 8.1e-13
NP_001275753 (OMIM: 601918) growth/differentiation ( 366) 273 73.6 8.1e-13
XP_011541611 (OMIM: 601918) PREDICTED: growth/diff ( 366) 273 73.6 8.1e-13
XP_005272014 (OMIM: 601918) PREDICTED: growth/diff ( 366) 273 73.6 8.1e-13
XP_011541610 (OMIM: 601918) PREDICTED: growth/diff ( 454) 273 73.6 9.8e-13
NP_005251 (OMIM: 601918) growth/differentiation fa ( 454) 273 73.6 9.8e-13
XP_006719257 (OMIM: 603936) PREDICTED: growth/diff ( 407) 270 72.9 1.5e-12
NP_005802 (OMIM: 603936) growth/differentiation fa ( 407) 270 72.9 1.5e-12
>>NP_065685 (OMIM: 606522,613702,613703,613704) growth/d (364 aa)
initn: 2512 init1: 2512 opt: 2512 Z-score: 3236.0 bits: 607.4 E(85289): 1.6e-173
Smith-Waterman score: 2512; 99.7% identity (99.7% similar) in 364 aa overlap (1-364:1-364)
10 20 30 40 50 60
pF1KE3 MLRFLPDLAFSFLLILALGQAVQFQEYVFLQFLGLDKAPSPQKFQPVPYILKKIFQDREA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 MLRFLPDLAFSFLLILALGQAVQFQEYVFLQFLGLDKAPSPQKFQPVPYILKKIFQDREA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 AATTGVSRDLCYVKELGVRGNVLRFLPDQGFFLYPKKISQASSCLQKLLYFNLSAIKERE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 AATTGVSRDLCYVKELGVRGNVLRFLPDQGFFLYPKKISQASSCLQKLLYFNLSAIKERE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 QLTLAQLGLDLGPNSYYNLGPELELALFLVQEPHVWGQTTPKPGKMFVLRSVPWPQGAVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 QLTLAQLGLDLGPNSYYNLGPELELALFLVQEPHVWGQTTPKPGKMFVLRSVPWPQGAVH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 FNLLDVAKDWNDNPRKNFGLFLEILVKEDRDSRVNFQPEDTCARLRCSLHASLLVVTLNP
:::::::::::::::::::::::::::::::: :::::::::::::::::::::::::::
NP_065 FNLLDVAKDWNDNPRKNFGLFLEILVKEDRDSGVNFQPEDTCARLRCSLHASLLVVTLNP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 DQCHPSRKRRAAIPVPKLSCKNLCHRHQLFINFRDLGWHKWIIAPKGFMANYCHGECPFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 DQCHPSRKRRAAIPVPKLSCKNLCHRHQLFINFRDLGWHKWIIAPKGFMANYCHGECPFS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 LTISLNSSNYAFMQALMHAVDPEIPQAVCIPTKLSPISMLYQDNNDNVILRHYEDMVVDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_065 LTISLNSSNYAFMQALMHAVDPEIPQAVCIPTKLSPISMLYQDNNDNVILRHYEDMVVDE
310 320 330 340 350 360
pF1KE3 CGCG
::::
NP_065 CGCG
>>NP_001483 (OMIM: 187500,208530,217095,602880,613854) e (372 aa)
initn: 595 init1: 222 opt: 524 Z-score: 674.4 bits: 133.4 E(85289): 8e-31
Smith-Waterman score: 701; 36.8% identity (62.6% similar) in 356 aa overlap (29-363:39-371)
10 20 30 40 50
pF1KE3 MLRFLPDLAFSFLLILALGQAVQFQEYVFLQFLGL-DKAPSPQKFQPVPYILKKIFQD
.:: ::: :. . ...::: .. ..:.
NP_001 CGHHLLLLLALLLPSLPLTRAPVPPGPAAALLQALGLRDEPQGAPRLRPVPPVMWRLFRR
10 20 30 40 50 60
60 70 80 90 100
pF1KE3 REAAATT--------GVSRDLCYVKELGVRGNVLRFLPDQGFFLYPKKISQASS----CL
:. : ::. . :.:.:::: ::..: .::.: : . :. .: :
NP_001 RDPQETRSGSRRTSPGVTLQPCHVEELGVAGNIVRHIPDRG---APTRASEPASAAGHCP
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE3 QKLLYFNLSAIKEREQLTLAQLGLDLGPNSYYNLGPELELALFLVQEPHVWGQTTPKPGK
. . :.:::.. :. . :.: : .. . .:: : ..: . : ::
NP_001 EWTVVFDLSAVEPAERPSRARLELRFAAAA--AAAPEGGWELSVAQAGQGAGAD---PGP
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE3 MFVLRSVPWPQGAVHFNLLDVAKDWNDNPRKNFGLFLEILVKEDRDSRVNFQPEDTCARL
... . :: :. .:: .: : : .: : . .. . .::::
NP_001 VLLRQLVPALGPPVRAELLGAA--WARNASWPRSLRLALALRP--------RAPAACARL
190 200 210 220 230
230 240 250 260 270 280
pF1KE3 RCSLHASLLVVTLNPDQCHP-SRKRRAAIPVPKLSCKNLCHRHQLFINFRDLGWHKWIIA
.::::.:::.: ::: .: :: : :: . . :. ..:...::..:::.:.::
NP_001 A---EASLLLVTLDPRLCHPLARPRRDAEPVLGGGPGGACRARRLYVSFREVGWHRWVIA
240 250 260 270 280
290 300 310 320 330
pF1KE3 PKGFMANYCHGECPFSLTISLNSS----NYAFMQALMHAVDP---EIPQAVCIPTKLSPI
:.::.::::.:.: . ...: ... :.: ..:::::. : ..: :.:..::::
NP_001 PRGFLANYCQGQCALPVALSGSGGPPALNHAVLRALMHAAAPGAADLP--CCVPARLSPI
290 300 310 320 330 340
340 350 360
pF1KE3 SMLYQDNNDNVILRHYEDMVVDECGCG
:.:. ::.:::.::.:::::::::::
NP_001 SVLFFDNSDNVVLRQYEDMVVDECGCR
350 360 370
>>NP_001191 (OMIM: 112261,112600,235200) bone morphogene (396 aa)
initn: 485 init1: 462 opt: 522 Z-score: 671.4 bits: 132.9 E(85289): 1.2e-30
Smith-Waterman score: 567; 31.1% identity (61.7% similar) in 360 aa overlap (26-363:54-395)
10 20 30 40 50
pF1KE3 MLRFLPDLAFSFLLILALGQAVQFQEYVFLQFLGLDKAPSPQKFQPVPYILKKIF
: .:...:: . :.:.. :: . ..
NP_001 LVPELGRRKFAAASSGRPSSQPSDEVLSEFELRLLSMFGLKQRPTPSRDAVVPPYMLDLY
30 40 50 60 70 80
60 70 80 90 100 110
pF1KE3 QDREAAATTGVSRDLCYVKELGVRGNVLR-FLPDQGFFLYPKKISQASSCLQKLLYFNLS
:. .. : ... . :.:..: : .... ... ..:. . ..::::
NP_001 --RRHSGQPGSPAPDHRLERAASRANTVRSFHHEESL----EELPETSGKTTRRFFFNLS
90 100 110 120 130
120 130 140 150 160
pF1KE3 AIKEREQLTLAQLGL------D-LGPNSYYNLGPELELALFLVQEPHVWGQTTPKPGKMF
.: .: .: :.: . : :: :: .. .. .. . .: . .. : ...
NP_001 SIPTEEFITSAELQVFREQMQDALGNNSSFHH----RINIYEIIKPATANSKFPVT-RLL
140 150 160 170 180 190
170 180 190 200 210
pF1KE3 VLRSVPWPQGAVHFNLLDVAKD---WNDNPRKNFGLFLEILVKEDRD---------SRVN
: : :.: ... .::. :. . . : :. .:. :... ::
NP_001 DTRLV--NQNASRWESFDVTPAVMRWTAQGHANHGFVVEVAHLEEKQGVSKRHVRISRSL
200 210 220 230 240 250
220 230 240 250 260 270
pF1KE3 FQPEDTCARLRCSLHASLLVVTLNPDQCHP--SRKRRAAIPVPKLSCKNLCHRHQLFINF
: : . ...: :::. . . :: .:..: : . :. :.:: :...:
NP_001 HQDEHSWSQIR-----PLLVTFGHDGKGHPLHKREKRQAKHKQRKRLKSSCKRHPLYVDF
260 270 280 290 300
280 290 300 310 320 330
pF1KE3 RDLGWHKWIIAPKGFMANYCHGECPFSLTISLNSSNYAFMQALMHAVDPEIPQAVCIPTK
:.::. ::.:: :. : :::::::: :. :::.:.:..:.:...:. .::.: :.::.
NP_001 SDVGWNDWIVAPPGYHAFYCHGECPFPLADHLNSTNHAIVQTLVNSVNSKIPKACCVPTE
310 320 330 340 350 360
340 350 360
pF1KE3 LSPISMLYQDNNDNVILRHYEDMVVDECGCG
:: ::::: :.:..:.:..:.::::. :::
NP_001 LSAISMLYLDENEKVVLKNYQDMVVEGCGCR
370 380 390
>>XP_011527625 (OMIM: 112261,112600,235200) PREDICTED: b (240 aa)
initn: 485 init1: 462 opt: 502 Z-score: 649.0 bits: 128.1 E(85289): 2.1e-29
Smith-Waterman score: 502; 39.2% identity (67.5% similar) in 194 aa overlap (181-363:51-239)
160 170 180 190 200 210
pF1KE3 QEPHVWGQTTPKPGKMFVLRSVPWPQGAVHFNLLDVAKDWNDNPRKNFGLFLEILVKEDR
:.. .. :. . . : :. .:. :..
XP_011 IKPATANSKFPVTRLLDTRLVNQNASRWESFDVTPAVMRWTAQGHANHGFVVEVAHLEEK
30 40 50 60 70 80
220 230 240 250
pF1KE3 D---------SRVNFQPEDTCARLRCSLHASLLVVTLNPDQCHP--SRKRRAAIPVPKLS
. :: : : . ...: :::. . . :: .:..: : .
XP_011 QGVSKRHVRISRSLHQDEHSWSQIR-----PLLVTFGHDGKGHPLHKREKRQAKHKQRKR
90 100 110 120 130
260 270 280 290 300 310
pF1KE3 CKNLCHRHQLFINFRDLGWHKWIIAPKGFMANYCHGECPFSLTISLNSSNYAFMQALMHA
:. :.:: :...: :.::. ::.:: :. : :::::::: :. :::.:.:..:.:...
XP_011 LKSSCKRHPLYVDFSDVGWNDWIVAPPGYHAFYCHGECPFPLADHLNSTNHAIVQTLVNS
140 150 160 170 180 190
320 330 340 350 360
pF1KE3 VDPEIPQAVCIPTKLSPISMLYQDNNDNVILRHYEDMVVDECGCG
:. .::.: :.::.:: ::::: :.:..:.:..:.::::. :::
XP_011 VNSKIPKACCVPTELSAISMLYLDENEKVVLKNYQDMVVEGCGCR
200 210 220 230 240
>>XP_016877093 (OMIM: 112262,600625,607932) PREDICTED: b (345 aa)
initn: 494 init1: 445 opt: 460 Z-score: 592.4 bits: 118.1 E(85289): 2.9e-26
Smith-Waterman score: 534; 31.5% identity (60.7% similar) in 356 aa overlap (33-363:2-344)
10 20 30 40 50 60
pF1KE3 RFLPDLAFSFLLILALGQAVQFQEYVFLQFLGLDKAPSPQKFQPVPYILKKIF--QDREA
.:: . :.:.: .: .. .. :. :
XP_016 MFGLRRRPQPSKSAVIPDYMRDLYRLQSGEE
10 20 30
70 80 90 100 110 120
pF1KE3 AATTGVSRDLCYVKELGVRGNVLRFLPDQGFFLYPKKISQASSCLQKLLYFNLSAIKERE
: : : .. . :.:..: . . . :. :. ..: ::::.: : :
XP_016 EEEQIHSTGLEYPERPASRANTVRSFHHEEHLENIPGTSENSAF--RFL-FNLSSIPENE
40 50 60 70 80
130 140 150 160 170
pF1KE3 QLTLAQLGL-----DLGPNSYYNLGPELELALFLVQEPHVWGQTTPKPGKMFVLRSVPWP
.. :.: : : ::. .. : . .. .. :..: . ...: .: .
XP_016 VISSAELRLFREQVDQGPD--WERGFH-RINIYEVMKPPA--EVVPGHLITRLLDTRLVH
90 100 110 120 130 140
180 190 200 210 220
pF1KE3 QGAVHFNLLDVAKD---WNDNPRKNFGLFLEIL------VKEDRDSRVNFQ-PEDTC--A
....... .::. :. . . :.:: .:. ... . :.. . :. . :
XP_016 HNVTRWETFDVSPAVLRWTREKQPNYGLAIEVTHLHQTRTHQGQHVRISRSLPQGSGNWA
150 160 170 180 190 200
230 240 250 260 270
pF1KE3 RLRCSLHASLLVVTLNPDQCHPSRKRRAAIPVPKLSC-----KNL-CHRHQLFINFRDLG
.:: :::. . . : .:: : :: :: :.::.:...: :.:
XP_016 QLR-----PLLVTFGHDGRGHALTRRRRAKRSPKHHSQRARKKNKNCRRHSLYVDFSDVG
210 220 230 240 250
280 290 300 310 320 330
pF1KE3 WHKWIIAPKGFMANYCHGECPFSLTISLNSSNYAFMQALMHAVDPEIPQAVCIPTKLSPI
:. ::.:: :..: ::::.::: :. :::.:.:..:.:...:. ::.: :.::.:: :
XP_016 WNDWIVAPPGYQAFYCHGDCPFPLADHLNSTNHAIVQTLVNSVNSSIPKACCVPTELSAI
260 270 280 290 300 310
340 350 360
pF1KE3 SMLYQDNNDNVILRHYEDMVVDECGCG
:::: :. :.:.:..:..:::. :::
XP_016 SMLYLDEYDKVVLKNYQEMVVEGCGCR
320 330 340
>>XP_016877094 (OMIM: 112262,600625,607932) PREDICTED: b (345 aa)
initn: 494 init1: 445 opt: 460 Z-score: 592.4 bits: 118.1 E(85289): 2.9e-26
Smith-Waterman score: 534; 31.5% identity (60.7% similar) in 356 aa overlap (33-363:2-344)
10 20 30 40 50 60
pF1KE3 RFLPDLAFSFLLILALGQAVQFQEYVFLQFLGLDKAPSPQKFQPVPYILKKIF--QDREA
.:: . :.:.: .: .. .. :. :
XP_016 MFGLRRRPQPSKSAVIPDYMRDLYRLQSGEE
10 20 30
70 80 90 100 110 120
pF1KE3 AATTGVSRDLCYVKELGVRGNVLRFLPDQGFFLYPKKISQASSCLQKLLYFNLSAIKERE
: : : .. . :.:..: . . . :. :. ..: ::::.: : :
XP_016 EEEQIHSTGLEYPERPASRANTVRSFHHEEHLENIPGTSENSAF--RFL-FNLSSIPENE
40 50 60 70 80
130 140 150 160 170
pF1KE3 QLTLAQLGL-----DLGPNSYYNLGPELELALFLVQEPHVWGQTTPKPGKMFVLRSVPWP
.. :.: : : ::. .. : . .. .. :..: . ...: .: .
XP_016 VISSAELRLFREQVDQGPD--WERGFH-RINIYEVMKPPA--EVVPGHLITRLLDTRLVH
90 100 110 120 130 140
180 190 200 210 220
pF1KE3 QGAVHFNLLDVAKD---WNDNPRKNFGLFLEIL------VKEDRDSRVNFQ-PEDTC--A
....... .::. :. . . :.:: .:. ... . :.. . :. . :
XP_016 HNVTRWETFDVSPAVLRWTREKQPNYGLAIEVTHLHQTRTHQGQHVRISRSLPQGSGNWA
150 160 170 180 190 200
230 240 250 260 270
pF1KE3 RLRCSLHASLLVVTLNPDQCHPSRKRRAAIPVPKLSC-----KNL-CHRHQLFINFRDLG
.:: :::. . . : .:: : :: :: :.::.:...: :.:
XP_016 QLR-----PLLVTFGHDGRGHALTRRRRAKRSPKHHSQRARKKNKNCRRHSLYVDFSDVG
210 220 230 240 250
280 290 300 310 320 330
pF1KE3 WHKWIIAPKGFMANYCHGECPFSLTISLNSSNYAFMQALMHAVDPEIPQAVCIPTKLSPI
:. ::.:: :..: ::::.::: :. :::.:.:..:.:...:. ::.: :.::.:: :
XP_016 WNDWIVAPPGYQAFYCHGDCPFPLADHLNSTNHAIVQTLVNSVNSSIPKACCVPTELSAI
260 270 280 290 300 310
340 350 360
pF1KE3 SMLYQDNNDNVILRHYEDMVVDECGCG
:::: :. :.:.:..:..:::. :::
XP_016 SMLYLDEYDKVVLKNYQEMVVEGCGCR
320 330 340
>>NP_570911 (OMIM: 112262,600625,607932) bone morphogene (408 aa)
initn: 494 init1: 445 opt: 460 Z-score: 591.3 bits: 118.2 E(85289): 3.4e-26
Smith-Waterman score: 551; 31.8% identity (61.1% similar) in 365 aa overlap (26-363:58-407)
10 20 30 40 50
pF1KE3 MLRFLPDLAFSFLLILALGQAVQFQEYVFLQFLGLDKAPSPQKFQPVPYILKKIF
: ..::..:: . :.:.: .: .. ..
NP_570 PETGKKKVAEIQGHAGGRRSGQSHELLRDFEATLLQMFGLRRRPQPSKSAVIPDYMRDLY
30 40 50 60 70 80
60 70 80 90 100 110
pF1KE3 --QDREAAATTGVSRDLCYVKELGVRGNVLRFLPDQGFFLYPKKISQASSCLQKLLYFNL
:. : : : : .. . :.:..: . . . :. :. ..: :::
NP_570 RLQSGEEEEEQIHSTGLEYPERPASRANTVRSFHHEEHLENIPGTSENSAF--RFL-FNL
90 100 110 120 130 140
120 130 140 150 160
pF1KE3 SAIKEREQLTLAQLGL-----DLGPNSYYNLGPELELALFLVQEPHVWGQTTPKPGKMF-
:.: : : .. :.: : : ::. .. : . .. .. :..: . ::...
NP_570 SSIPENEVISSAELRLFREQVDQGPD--WERGFH-RINIYEVMKP----PAEVVPGHLIT
150 160 170 180 190
170 180 190 200 210
pF1KE3 -VLRSVPWPQGAVHFNLLDVAKD---WNDNPRKNFGLFLEIL------VKEDRDSRVNFQ
.: . ....... .::. :. . . :.:: .:. ... . :.. .
NP_570 RLLDTRLVHHNVTRWETFDVSPAVLRWTREKQPNYGLAIEVTHLHQTRTHQGQHVRISRS
200 210 220 230 240 250
220 230 240 250 260
pF1KE3 -PEDTC--ARLRCSLHASLLVVTLNPDQCHPSRKRRAAIPVPKLSC-----KNL-CHRHQ
:. . :.:: :::. . . : .:: : :: :: :.::.
NP_570 LPQGSGNWAQLR-----PLLVTFGHDGRGHALTRRRRAKRSPKHHSQRARKKNKNCRRHS
260 270 280 290 300 310
270 280 290 300 310 320
pF1KE3 LFINFRDLGWHKWIIAPKGFMANYCHGECPFSLTISLNSSNYAFMQALMHAVDPEIPQAV
:...: :.::. ::.:: :..: ::::.::: :. :::.:.:..:.:...:. ::.:
NP_570 LYVDFSDVGWNDWIVAPPGYQAFYCHGDCPFPLADHLNSTNHAIVQTLVNSVNSSIPKAC
320 330 340 350 360 370
330 340 350 360
pF1KE3 CIPTKLSPISMLYQDNNDNVILRHYEDMVVDECGCG
:.::.:: ::::: :. :.:.:..:..:::. :::
NP_570 CVPTELSAISMLYLDEYDKVVLKNYQEMVVEGCGCR
380 390 400
>>NP_001193 (OMIM: 112262,600625,607932) bone morphogene (408 aa)
initn: 494 init1: 445 opt: 460 Z-score: 591.3 bits: 118.2 E(85289): 3.4e-26
Smith-Waterman score: 551; 31.8% identity (61.1% similar) in 365 aa overlap (26-363:58-407)
10 20 30 40 50
pF1KE3 MLRFLPDLAFSFLLILALGQAVQFQEYVFLQFLGLDKAPSPQKFQPVPYILKKIF
: ..::..:: . :.:.: .: .. ..
NP_001 PETGKKKVAEIQGHAGGRRSGQSHELLRDFEATLLQMFGLRRRPQPSKSAVIPDYMRDLY
30 40 50 60 70 80
60 70 80 90 100 110
pF1KE3 --QDREAAATTGVSRDLCYVKELGVRGNVLRFLPDQGFFLYPKKISQASSCLQKLLYFNL
:. : : : : .. . :.:..: . . . :. :. ..: :::
NP_001 RLQSGEEEEEQIHSTGLEYPERPASRANTVRSFHHEEHLENIPGTSENSAF--RFL-FNL
90 100 110 120 130 140
120 130 140 150 160
pF1KE3 SAIKEREQLTLAQLGL-----DLGPNSYYNLGPELELALFLVQEPHVWGQTTPKPGKMF-
:.: : : .. :.: : : ::. .. : . .. .. :..: . ::...
NP_001 SSIPENEVISSAELRLFREQVDQGPD--WERGFH-RINIYEVMKP----PAEVVPGHLIT
150 160 170 180 190
170 180 190 200 210
pF1KE3 -VLRSVPWPQGAVHFNLLDVAKD---WNDNPRKNFGLFLEIL------VKEDRDSRVNFQ
.: . ....... .::. :. . . :.:: .:. ... . :.. .
NP_001 RLLDTRLVHHNVTRWETFDVSPAVLRWTREKQPNYGLAIEVTHLHQTRTHQGQHVRISRS
200 210 220 230 240 250
220 230 240 250 260
pF1KE3 -PEDTC--ARLRCSLHASLLVVTLNPDQCHPSRKRRAAIPVPKLSC-----KNL-CHRHQ
:. . :.:: :::. . . : .:: : :: :: :.::.
NP_001 LPQGSGNWAQLR-----PLLVTFGHDGRGHALTRRRRAKRSPKHHSQRARKKNKNCRRHS
260 270 280 290 300 310
270 280 290 300 310 320
pF1KE3 LFINFRDLGWHKWIIAPKGFMANYCHGECPFSLTISLNSSNYAFMQALMHAVDPEIPQAV
:...: :.::. ::.:: :..: ::::.::: :. :::.:.:..:.:...:. ::.:
NP_001 LYVDFSDVGWNDWIVAPPGYQAFYCHGDCPFPLADHLNSTNHAIVQTLVNSVNSSIPKAC
320 330 340 350 360 370
330 340 350 360
pF1KE3 CIPTKLSPISMLYQDNNDNVILRHYEDMVVDECGCG
:.::.:: ::::: :. :.:.:..:..:::. :::
NP_001 CVPTELSAISMLYLDEYDKVVLKNYQEMVVEGCGCR
380 390 400
>>XP_005268072 (OMIM: 112262,600625,607932) PREDICTED: b (408 aa)
initn: 494 init1: 445 opt: 460 Z-score: 591.3 bits: 118.2 E(85289): 3.4e-26
Smith-Waterman score: 551; 31.8% identity (61.1% similar) in 365 aa overlap (26-363:58-407)
10 20 30 40 50
pF1KE3 MLRFLPDLAFSFLLILALGQAVQFQEYVFLQFLGLDKAPSPQKFQPVPYILKKIF
: ..::..:: . :.:.: .: .. ..
XP_005 PETGKKKVAEIQGHAGGRRSGQSHELLRDFEATLLQMFGLRRRPQPSKSAVIPDYMRDLY
30 40 50 60 70 80
60 70 80 90 100 110
pF1KE3 --QDREAAATTGVSRDLCYVKELGVRGNVLRFLPDQGFFLYPKKISQASSCLQKLLYFNL
:. : : : : .. . :.:..: . . . :. :. ..: :::
XP_005 RLQSGEEEEEQIHSTGLEYPERPASRANTVRSFHHEEHLENIPGTSENSAF--RFL-FNL
90 100 110 120 130 140
120 130 140 150 160
pF1KE3 SAIKEREQLTLAQLGL-----DLGPNSYYNLGPELELALFLVQEPHVWGQTTPKPGKMF-
:.: : : .. :.: : : ::. .. : . .. .. :..: . ::...
XP_005 SSIPENEVISSAELRLFREQVDQGPD--WERGFH-RINIYEVMKP----PAEVVPGHLIT
150 160 170 180 190
170 180 190 200 210
pF1KE3 -VLRSVPWPQGAVHFNLLDVAKD---WNDNPRKNFGLFLEIL------VKEDRDSRVNFQ
.: . ....... .::. :. . . :.:: .:. ... . :.. .
XP_005 RLLDTRLVHHNVTRWETFDVSPAVLRWTREKQPNYGLAIEVTHLHQTRTHQGQHVRISRS
200 210 220 230 240 250
220 230 240 250 260
pF1KE3 -PEDTC--ARLRCSLHASLLVVTLNPDQCHPSRKRRAAIPVPKLSC-----KNL-CHRHQ
:. . :.:: :::. . . : .:: : :: :: :.::.
XP_005 LPQGSGNWAQLR-----PLLVTFGHDGRGHALTRRRRAKRSPKHHSQRARKKNKNCRRHS
260 270 280 290 300 310
270 280 290 300 310 320
pF1KE3 LFINFRDLGWHKWIIAPKGFMANYCHGECPFSLTISLNSSNYAFMQALMHAVDPEIPQAV
:...: :.::. ::.:: :..: ::::.::: :. :::.:.:..:.:...:. ::.:
XP_005 LYVDFSDVGWNDWIVAPPGYQAFYCHGDCPFPLADHLNSTNHAIVQTLVNSVNSSIPKAC
320 330 340 350 360 370
330 340 350 360
pF1KE3 CIPTKLSPISMLYQDNNDNVILRHYEDMVVDECGCG
:.::.:: ::::: :. :.:.:..:..:::. :::
XP_005 CVPTELSAISMLYLDEYDKVVLKNYQEMVVEGCGCR
380 390 400
>>XP_016877092 (OMIM: 112262,600625,607932) PREDICTED: b (408 aa)
initn: 494 init1: 445 opt: 460 Z-score: 591.3 bits: 118.2 E(85289): 3.4e-26
Smith-Waterman score: 551; 31.8% identity (61.1% similar) in 365 aa overlap (26-363:58-407)
10 20 30 40 50
pF1KE3 MLRFLPDLAFSFLLILALGQAVQFQEYVFLQFLGLDKAPSPQKFQPVPYILKKIF
: ..::..:: . :.:.: .: .. ..
XP_016 PETGKKKVAEIQGHAGGRRSGQSHELLRDFEATLLQMFGLRRRPQPSKSAVIPDYMRDLY
30 40 50 60 70 80
60 70 80 90 100 110
pF1KE3 --QDREAAATTGVSRDLCYVKELGVRGNVLRFLPDQGFFLYPKKISQASSCLQKLLYFNL
:. : : : : .. . :.:..: . . . :. :. ..: :::
XP_016 RLQSGEEEEEQIHSTGLEYPERPASRANTVRSFHHEEHLENIPGTSENSAF--RFL-FNL
90 100 110 120 130 140
120 130 140 150 160
pF1KE3 SAIKEREQLTLAQLGL-----DLGPNSYYNLGPELELALFLVQEPHVWGQTTPKPGKMF-
:.: : : .. :.: : : ::. .. : . .. .. :..: . ::...
XP_016 SSIPENEVISSAELRLFREQVDQGPD--WERGFH-RINIYEVMKP----PAEVVPGHLIT
150 160 170 180 190
170 180 190 200 210
pF1KE3 -VLRSVPWPQGAVHFNLLDVAKD---WNDNPRKNFGLFLEIL------VKEDRDSRVNFQ
.: . ....... .::. :. . . :.:: .:. ... . :.. .
XP_016 RLLDTRLVHHNVTRWETFDVSPAVLRWTREKQPNYGLAIEVTHLHQTRTHQGQHVRISRS
200 210 220 230 240 250
220 230 240 250 260
pF1KE3 -PEDTC--ARLRCSLHASLLVVTLNPDQCHPSRKRRAAIPVPKLSC-----KNL-CHRHQ
:. . :.:: :::. . . : .:: : :: :: :.::.
XP_016 LPQGSGNWAQLR-----PLLVTFGHDGRGHALTRRRRAKRSPKHHSQRARKKNKNCRRHS
260 270 280 290 300 310
270 280 290 300 310 320
pF1KE3 LFINFRDLGWHKWIIAPKGFMANYCHGECPFSLTISLNSSNYAFMQALMHAVDPEIPQAV
:...: :.::. ::.:: :..: ::::.::: :. :::.:.:..:.:...:. ::.:
XP_016 LYVDFSDVGWNDWIVAPPGYQAFYCHGDCPFPLADHLNSTNHAIVQTLVNSVNSSIPKAC
320 330 340 350 360 370
330 340 350 360
pF1KE3 CIPTKLSPISMLYQDNNDNVILRHYEDMVVDECGCG
:.::.:: ::::: :. :.:.:..:..:::. :::
XP_016 CVPTELSAISMLYLDEYDKVVLKNYQEMVVEGCGCR
380 390 400
364 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 22:28:10 2016 done: Sun Nov 6 22:28:12 2016
Total Scan time: 7.900 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]