Result of FASTA (omim) for
pFN21AE3604
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3604, 354 aa
1>>>pF1KE3604 354 - 354 aa - 354 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.9037+/-0.00038; mu= 0.3433+/- 0.024
mean_var=208.2249+/-43.562, 0's: 0 Z-trim(121.0): 36 B-trim: 1487 in 2/51
Lambda= 0.088881
statistics sampled from 36891 (36929) to 36891 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.778), E-opt: 0.2 (0.433), width: 16
Scan time: 8.570
The best scores are: opt bits E(85289)
XP_005268211 (OMIM: 603544) PREDICTED: cyclin-K is ( 580) 2154 288.6 2.4e-77
NP_001092872 (OMIM: 603544) cyclin-K [Homo sapiens ( 580) 2154 288.6 2.4e-77
XP_011535577 (OMIM: 603544) PREDICTED: cyclin-K is ( 580) 2154 288.6 2.4e-77
NP_001231 (OMIM: 143055) cyclin-T1 isoform a [Homo ( 726) 484 74.5 8.2e-13
NP_001232 (OMIM: 603862) cyclin-T2 isoform a [Homo ( 663) 449 70.0 1.7e-11
NP_490595 (OMIM: 603862) cyclin-T2 isoform b [Homo ( 730) 449 70.0 1.8e-11
NP_112199 (OMIM: 613482) cyclin-L2 isoform A [Homo ( 520) 394 62.9 1.9e-09
NP_001295114 (OMIM: 613384) cyclin-L1 isoform 2 [H ( 428) 392 62.6 1.9e-09
XP_006713773 (OMIM: 613384) PREDICTED: cyclin-L1 i ( 493) 392 62.6 2.1e-09
NP_064703 (OMIM: 613384) cyclin-L1 isoform 1 [Homo ( 526) 392 62.6 2.2e-09
NP_001264771 (OMIM: 143055) cyclin-T1 isoform b [H ( 184) 375 60.1 4.4e-09
NP_689487 (OMIM: 300707,300708) cyclin-related pro ( 248) 343 56.1 9.7e-08
NP_001124469 (OMIM: 300707,300708) cyclin-related ( 228) 320 53.1 7e-07
XP_005277977 (OMIM: 300707,300708) PREDICTED: cycl ( 238) 307 51.5 2.3e-06
XP_005277978 (OMIM: 300707,300708) PREDICTED: cycl ( 218) 284 48.5 1.7e-05
XP_011529516 (OMIM: 300707,300708) PREDICTED: cycl ( 206) 271 46.8 5e-05
XP_011529517 (OMIM: 300707,300708) PREDICTED: cycl ( 206) 271 46.8 5e-05
XP_016860717 (OMIM: 603862) PREDICTED: cyclin-T2 i ( 642) 280 48.3 5.5e-05
XP_016860716 (OMIM: 603862) PREDICTED: cyclin-T2 i ( 709) 280 48.3 6e-05
NP_001034666 (OMIM: 613482) cyclin-L2 isoform B [H ( 226) 267 46.3 7.7e-05
XP_016875686 (OMIM: 143055) PREDICTED: cyclin-T1 i ( 646) 273 47.4 0.0001
XP_006715657 (OMIM: 123838) PREDICTED: cyclin-C is ( 282) 264 46.0 0.00012
NP_005181 (OMIM: 123838) cyclin-C isoform a [Homo ( 283) 264 46.0 0.00012
XP_011540518 (OMIM: 613482) PREDICTED: cyclin-L2 i ( 553) 234 42.4 0.0029
XP_011511313 (OMIM: 613384) PREDICTED: cyclin-L1 i ( 371) 229 41.6 0.0033
XP_005247705 (OMIM: 613384) PREDICTED: cyclin-L1 i ( 371) 229 41.6 0.0033
>>XP_005268211 (OMIM: 603544) PREDICTED: cyclin-K isofor (580 aa)
initn: 2194 init1: 2141 opt: 2154 Z-score: 1509.8 bits: 288.6 E(85289): 2.4e-77
Smith-Waterman score: 2154; 93.8% identity (95.0% similar) in 337 aa overlap (1-336:1-331)
10 20 30 40 50 60
pF1KE3 MKENKENSSPSVTSANLDHTKPCWYWDKKDLAHTPSQLEGLDPATEARYRREGARFIFDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MKENKENSSPSVTSANLDHTKPCWYWDKKDLAHTPSQLEGLDPATEARYRREGARFIFDV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 GTRLGLHYDTLATGIIYFHRFYMFHSFKQFPRYVTGACCLFLAGKIEETPKKCKDIIKTA
:::::::::::::::::::::::::::::::::::::::::::::.::::::::::::::
XP_005 GTRLGLHYDTLATGIIYFHRFYMFHSFKQFPRYVTGACCLFLAGKVEETPKKCKDIIKTA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 RSLLNDVQFGQFGDDPKEEVMVLERILLQTIKFDLQVEHPYQFLLKYAKQLKGDKNKIQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RSLLNDVQFGQFGDDPKEEVMVLERILLQTIKFDLQVEHPYQFLLKYAKQLKGDKNKIQK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 LVQMAWTFVNDSLCTTLSLQWEPEIIAVAVMYLAGRLCKFEIQEWTSKPMYRRWWEQFVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LVQMAWTFVNDSLCTTLSLQWEPEIIAVAVMYLAGRLCKFEIQEWTSKPMYRRWWEQFVQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 DVPVDVLEDICHQILDLYSQGKQQMPHHTPHQLQQPPSLQPTPQVPQVQQSQPSQSSEPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DVPVDVLEDICHQILDLYSQGKQQMPHHTPHQLQQPPSLQPTPQVPQVQQSQPSQSSEPS
250 260 270 280 290 300
310 320 330 340 350
pF1KE3 QPQQKDPLILLQGWACRQPATH-LLPSPLEDSLLCPRPFPHPACLQLGGWGGQPG
::::::: : .::: . ::: .: ::
XP_005 QPQQKDPQ---QPAQQQQPAQQPKKPSPQPSS---PRQVKRAVVVSPKEENKAAEPPPPK
310 320 330 340 350
XP_005 IPKIETTHPPLPPAHPPPDRKPPLAAALGEAEPPGPVDATDLPKVQIPPPAHPAPVHQPP
360 370 380 390 400 410
>>NP_001092872 (OMIM: 603544) cyclin-K [Homo sapiens] (580 aa)
initn: 2194 init1: 2141 opt: 2154 Z-score: 1509.8 bits: 288.6 E(85289): 2.4e-77
Smith-Waterman score: 2154; 93.8% identity (95.0% similar) in 337 aa overlap (1-336:1-331)
10 20 30 40 50 60
pF1KE3 MKENKENSSPSVTSANLDHTKPCWYWDKKDLAHTPSQLEGLDPATEARYRREGARFIFDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MKENKENSSPSVTSANLDHTKPCWYWDKKDLAHTPSQLEGLDPATEARYRREGARFIFDV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 GTRLGLHYDTLATGIIYFHRFYMFHSFKQFPRYVTGACCLFLAGKIEETPKKCKDIIKTA
:::::::::::::::::::::::::::::::::::::::::::::.::::::::::::::
NP_001 GTRLGLHYDTLATGIIYFHRFYMFHSFKQFPRYVTGACCLFLAGKVEETPKKCKDIIKTA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 RSLLNDVQFGQFGDDPKEEVMVLERILLQTIKFDLQVEHPYQFLLKYAKQLKGDKNKIQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RSLLNDVQFGQFGDDPKEEVMVLERILLQTIKFDLQVEHPYQFLLKYAKQLKGDKNKIQK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 LVQMAWTFVNDSLCTTLSLQWEPEIIAVAVMYLAGRLCKFEIQEWTSKPMYRRWWEQFVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LVQMAWTFVNDSLCTTLSLQWEPEIIAVAVMYLAGRLCKFEIQEWTSKPMYRRWWEQFVQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 DVPVDVLEDICHQILDLYSQGKQQMPHHTPHQLQQPPSLQPTPQVPQVQQSQPSQSSEPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DVPVDVLEDICHQILDLYSQGKQQMPHHTPHQLQQPPSLQPTPQVPQVQQSQPSQSSEPS
250 260 270 280 290 300
310 320 330 340 350
pF1KE3 QPQQKDPLILLQGWACRQPATH-LLPSPLEDSLLCPRPFPHPACLQLGGWGGQPG
::::::: : .::: . ::: .: ::
NP_001 QPQQKDPQ---QPAQQQQPAQQPKKPSPQPSS---PRQVKRAVVVSPKEENKAAEPPPPK
310 320 330 340 350
NP_001 IPKIETTHPPLPPAHPPPDRKPPLAAALGEAEPPGPVDATDLPKVQIPPPAHPAPVHQPP
360 370 380 390 400 410
>>XP_011535577 (OMIM: 603544) PREDICTED: cyclin-K isofor (580 aa)
initn: 2194 init1: 2141 opt: 2154 Z-score: 1509.8 bits: 288.6 E(85289): 2.4e-77
Smith-Waterman score: 2154; 93.8% identity (95.0% similar) in 337 aa overlap (1-336:1-331)
10 20 30 40 50 60
pF1KE3 MKENKENSSPSVTSANLDHTKPCWYWDKKDLAHTPSQLEGLDPATEARYRREGARFIFDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MKENKENSSPSVTSANLDHTKPCWYWDKKDLAHTPSQLEGLDPATEARYRREGARFIFDV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 GTRLGLHYDTLATGIIYFHRFYMFHSFKQFPRYVTGACCLFLAGKIEETPKKCKDIIKTA
:::::::::::::::::::::::::::::::::::::::::::::.::::::::::::::
XP_011 GTRLGLHYDTLATGIIYFHRFYMFHSFKQFPRYVTGACCLFLAGKVEETPKKCKDIIKTA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 RSLLNDVQFGQFGDDPKEEVMVLERILLQTIKFDLQVEHPYQFLLKYAKQLKGDKNKIQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RSLLNDVQFGQFGDDPKEEVMVLERILLQTIKFDLQVEHPYQFLLKYAKQLKGDKNKIQK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 LVQMAWTFVNDSLCTTLSLQWEPEIIAVAVMYLAGRLCKFEIQEWTSKPMYRRWWEQFVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LVQMAWTFVNDSLCTTLSLQWEPEIIAVAVMYLAGRLCKFEIQEWTSKPMYRRWWEQFVQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 DVPVDVLEDICHQILDLYSQGKQQMPHHTPHQLQQPPSLQPTPQVPQVQQSQPSQSSEPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DVPVDVLEDICHQILDLYSQGKQQMPHHTPHQLQQPPSLQPTPQVPQVQQSQPSQSSEPS
250 260 270 280 290 300
310 320 330 340 350
pF1KE3 QPQQKDPLILLQGWACRQPATH-LLPSPLEDSLLCPRPFPHPACLQLGGWGGQPG
::::::: : .::: . ::: .: ::
XP_011 QPQQKDPQ---QPAQQQQPAQQPKKPSPQPSS---PRQVKRAVVVSPKEENKAAEPPPPK
310 320 330 340 350
XP_011 IPKIETTHPPLPPAHPPPDRKPPLAAALGEAEPPGPVDATDLPKVQIPPPAHPAPVHQPP
360 370 380 390 400 410
>>NP_001231 (OMIM: 143055) cyclin-T1 isoform a [Homo sap (726 aa)
initn: 483 init1: 301 opt: 484 Z-score: 351.1 bits: 74.5 E(85289): 8.2e-13
Smith-Waterman score: 485; 32.7% identity (66.5% similar) in 260 aa overlap (24-275:12-254)
10 20 30 40 50 60
pF1KE3 MKENKENSSPSVTSANLDHTKPCWYWDKKDLAHTPSQLEGLDPATEARYRREGARFIFDV
::. ...: ..::. :.:: : ::...: .. :.
NP_001 MEGERKNNNKRWYFTREQLENSPSRRFGVDPDKELSYRQQAANLLQDM
10 20 30 40
70 80 90 100 110 120
pF1KE3 GTRLGLHYDTLATGIIYFHRFYMFHSFKQFPRYVTGACCLFLAGKIEETPKKCKDIIKTA
: ::.. :. :.:.:.:::::..:: ::: .. ::::.:.:: ::: . .::.:
NP_001 GQRLNVSQLTINTAIVYMHRFYMIQSFTQFPGNSVAPAALFLAAKVEEQPKKLEHVIKVA
50 60 70 80 90 100
130 140 150 160 170
pF1KE3 RSLLNDVQFGQFGDDPKE-------EVMVLERILLQTIKFDLQVEHPYQFLLKYAKQLKG
.. :. . .. : .: ....:: :.:::. :.: ..::. ..: .. ...
NP_001 HTCLHPQE--SLPDTRSEAYLQQVQDLVILESIILQTLGFELTIDHPHTHVVKCTQLVRA
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE3 DKNKIQKLVQMAWTFVNDSL-CTTLSLQWEPEIIAVAVMYLAGRLCKFEIQEWTSKPMYR
.:. :.: .. ....:: ::.:::. : ..: . ..:: ::. : . .
NP_001 SKD----LAQTSYFMATNSLHLTTFSLQYTPPVVACVCIHLA---CKWSNWEIPVSTDGK
170 180 190 200 210
240 250 260 270 280 290
pF1KE3 RWWEQFVQDVPVDVLEDICHQILDLYSQGKQQMPHHTPHQLQQPPSLQPTPQVPQVQQSQ
.::: : ...:... :..: :. ..::..:..
NP_001 HWWEYVDATVTLELLDELTHEFL--------QILEKTPNRLKRIWNWRACEAAKKTKADD
220 230 240 250 260 270
300 310 320 330 340 350
pF1KE3 PSQSSEPSQPQQKDPLILLQGWACRQPATHLLPSPLEDSLLCPRPFPHPACLQLGGWGGQ
NP_001 RGTDEKTSEQTILNMISQSSSDTTIAGLMSMSTSTTSAVPSLPVSEESSSNLTSVEMLPG
280 290 300 310 320 330
>>NP_001232 (OMIM: 603862) cyclin-T2 isoform a [Homo sap (663 aa)
initn: 410 init1: 260 opt: 449 Z-score: 327.4 bits: 70.0 E(85289): 1.7e-11
Smith-Waterman score: 449; 28.2% identity (63.0% similar) in 319 aa overlap (24-328:11-313)
10 20 30 40 50 60
pF1KE3 MKENKENSSPSVTSANLDHTKPCWYWDKKDLAHTPSQLEGLDPATEARYRREGARFIFDV
:.. ...: .:::. :.. : :...: .: ..
NP_001 MASGRGASSRWFFTREQLENTPSRRCGVEADKELSCRQQAANLIQEM
10 20 30 40
70 80 90 100 110 120
pF1KE3 GTRLGLHYDTLATGIIYFHRFYMFHSFKQFPRYVTGACCLFLAGKIEETPKKCKDIIKTA
: ::.. :. :.:.:.::::: ::: .: . . .. ::::.:.:: .: . .::.:
NP_001 GQRLNVSQLTINTAIVYMHRFYMHHSFTKFNKNIISSTALFLAAKVEEQARKLEHVIKVA
50 60 70 80 90 100
130 140 150 160 170
pF1KE3 RSLLN------DVQFGQFGDDPKEEVMVLERILLQTIKFDLQVEHPYQFLLKYAKQLKGD
.. :. :.. . .. .: ...:: :.:::. :.. .:::. ..: .. ....
NP_001 HACLHPLEPLLDTKCDAYLQQTQE-LVILETIMLQTLGFEITIEHPHTDVVKCTQLVRAS
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE3 KNKIQKLVQMAWTFVNDSL-CTTLSLQWEPEIIAVAVMYLAGRLCKFEIQEWTSKPMYRR
:. :.: .. ....:: ::. ::..: .:: . ..:: ::. : . ..
NP_001 KD----LAQTSYFMATNSLHLTTFCLQYKPTVIACVCIHLA---CKWSNWEIPVSTDGKH
170 180 190 200 210
240 250 260 270 280
pF1KE3 WWEQFVQDVPVDVLEDICHQILDLYSQGKQQMPHHTPHQLQQPPSLQPT-----PQVP-Q
::: : ...:... :..: :. ..::..:.. . . . :.: :
NP_001 WWEYVDPTVTLELLDELTHEFL--------QILEKTPNRLKKIRNWRANQAARKPKVDGQ
220 230 240 250 260 270
290 300 310 320 330 340
pF1KE3 VQQSQPSQSSEPSQPQQKDPLILLQ-GWACRQPATHLLPSPLEDSLLCPRPFPHPACLQL
:... :: .. : . . . . ..:.: .:.:.
NP_001 VSETPLLGSSLVQNSILVDSVTGVPTNPSFQKPSTSAFPAPVPLNSGNISVQDSHTSDNL
280 290 300 310 320 330
350
pF1KE3 GGWGGQPG
NP_001 SMLATGMPSTSYGLSSHQEWPQHQDSARTEQLYSQKQETSLSGSQYNINFQQGPSISLHS
340 350 360 370 380 390
>>NP_490595 (OMIM: 603862) cyclin-T2 isoform b [Homo sap (730 aa)
initn: 410 init1: 260 opt: 449 Z-score: 326.8 bits: 70.0 E(85289): 1.8e-11
Smith-Waterman score: 449; 28.2% identity (63.0% similar) in 319 aa overlap (24-328:11-313)
10 20 30 40 50 60
pF1KE3 MKENKENSSPSVTSANLDHTKPCWYWDKKDLAHTPSQLEGLDPATEARYRREGARFIFDV
:.. ...: .:::. :.. : :...: .: ..
NP_490 MASGRGASSRWFFTREQLENTPSRRCGVEADKELSCRQQAANLIQEM
10 20 30 40
70 80 90 100 110 120
pF1KE3 GTRLGLHYDTLATGIIYFHRFYMFHSFKQFPRYVTGACCLFLAGKIEETPKKCKDIIKTA
: ::.. :. :.:.:.::::: ::: .: . . .. ::::.:.:: .: . .::.:
NP_490 GQRLNVSQLTINTAIVYMHRFYMHHSFTKFNKNIISSTALFLAAKVEEQARKLEHVIKVA
50 60 70 80 90 100
130 140 150 160 170
pF1KE3 RSLLN------DVQFGQFGDDPKEEVMVLERILLQTIKFDLQVEHPYQFLLKYAKQLKGD
.. :. :.. . .. .: ...:: :.:::. :.. .:::. ..: .. ....
NP_490 HACLHPLEPLLDTKCDAYLQQTQE-LVILETIMLQTLGFEITIEHPHTDVVKCTQLVRAS
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE3 KNKIQKLVQMAWTFVNDSL-CTTLSLQWEPEIIAVAVMYLAGRLCKFEIQEWTSKPMYRR
:. :.: .. ....:: ::. ::..: .:: . ..:: ::. : . ..
NP_490 KD----LAQTSYFMATNSLHLTTFCLQYKPTVIACVCIHLA---CKWSNWEIPVSTDGKH
170 180 190 200 210
240 250 260 270 280
pF1KE3 WWEQFVQDVPVDVLEDICHQILDLYSQGKQQMPHHTPHQLQQPPSLQPT-----PQVP-Q
::: : ...:... :..: :. ..::..:.. . . . :.: :
NP_490 WWEYVDPTVTLELLDELTHEFL--------QILEKTPNRLKKIRNWRANQAARKPKVDGQ
220 230 240 250 260 270
290 300 310 320 330 340
pF1KE3 VQQSQPSQSSEPSQPQQKDPLILLQ-GWACRQPATHLLPSPLEDSLLCPRPFPHPACLQL
:... :: .. : . . . . ..:.: .:.:.
NP_490 VSETPLLGSSLVQNSILVDSVTGVPTNPSFQKPSTSAFPAPVPLNSGNISVQDSHTSDNL
280 290 300 310 320 330
350
pF1KE3 GGWGGQPG
NP_490 SMLATGMPSTSYGLSSHQEWPQHQDSARTEQLYSQKQETSLSGSQYNINFQQGPSISLHS
340 350 360 370 380 390
>>NP_112199 (OMIM: 613482) cyclin-L2 isoform A [Homo sap (520 aa)
initn: 371 init1: 184 opt: 394 Z-score: 290.7 bits: 62.9 E(85289): 1.9e-09
Smith-Waterman score: 400; 29.5% identity (59.1% similar) in 325 aa overlap (23-338:52-350)
10 20 30 40 50
pF1KE3 MKENKENSSPSVTSANLDHTKPCWYWDKKDLAHTPSQLEGLDPATEARYRRE
: : : : :::. ::: ::. :
NP_112 APGSGGAPSGSQGVLIGDRLYSGVLITLENCLLPDDK-LRFTPSMSSGLDTDTETDLRVV
30 40 50 60 70 80
60 70 80 90 100 110
pF1KE3 GARFIFDVGTRLGLHYDTLATGIIYFHRFYMFHSF-KQFPRYVTGACCLFLAGKIEETPK
: ..: .: : : ..::: . :.::.. .:: :. ..:. :: . ::.::::.:.
NP_112 GCELIQAAGILLRLPQVAMATGQVLFQRFFYTKSFVKHSMEHVSMAC-VHLASKIEEAPR
90 100 110 120 130
120 130 140 150 160
pF1KE3 KCKDIIKTARSL--LNDVQ------FGQFGDDPKEEVMVLERILLQTIKFDLQVEHPYQF
. .:.:.. . : : : . . : . :.... :: .:. . : ..:.::...
NP_112 RIRDVINVFHRLRQLRDKKKPVPLLLDQDYVNLKNQIIKAERRVLKELGFCVHVKHPHKI
140 150 160 170 180 190
170 180 190 200 210 220
pF1KE3 LLKYAKQLKGDKNKIQKLVQMAWTFVNDSLCTTLSLQWEPEIIAVAVMYLAGRLCKFEIQ
.. : . :. ..: :.::: .:...:::: : . ....:: :: : .:::.: .. .
NP_112 IVMYLQVLECERN--QHLVQTSWNYMNDSLRTDVFVRFQPESIACACIYLAARTLEIPL-
200 210 220 230 240 250
230 240 250 260 270 280
pF1KE3 EWTSKPMYRRWWEQFVQDVPVDVLEDICHQILDLYSQGKQQMPHHTPHQLQQPPSLQPTP
: .:. : . . ...:: .::.::.. : .. : . .. ...
NP_112 -----PNRPHWFLLF--GATEEEIQEICLKILQLYARKKVDLTHLEGEVEKRKHAIE---
260 270 280 290 300
290 300 310 320 330 340
pF1KE3 QVPQVQQSQPSQSSEPSQPQQKDPLILLQGWACRQPATHLLPSPLEDSLLCPRPFPHPAC
. . ... :. : .:.: . .:: .:. :: : . : :.
NP_112 -----EAKAQARGLLPGGTQ------VLDGTSGFSPAPKLVESPKEGKGSKPSPLSVKNT
310 320 330 340 350
350
pF1KE3 LQLGGWGGQPG
NP_112 KRRLEGAKKAKADSPVNGLPKGRESRSRSRSREQSYSRSPSRSASPKRRKSDSGSTSGGS
360 370 380 390 400 410
>>NP_001295114 (OMIM: 613384) cyclin-L1 isoform 2 [Homo (428 aa)
initn: 399 init1: 197 opt: 392 Z-score: 290.6 bits: 62.6 E(85289): 1.9e-09
Smith-Waterman score: 395; 29.0% identity (60.2% similar) in 314 aa overlap (11-304:48-345)
10 20 30 40
pF1KE3 MKENKENSSPSVTSANLDHTKPCWYWDKKDLAHTPSQLEG
: .: ..::. .. :. :::. .:
NP_001 AAPSAGGSSSGTTTTTTTTTGGILIGDRLYSEVSLTIDHS----LIPEERLSPTPSMQDG
20 30 40 50 60 70
50 60 70 80 90 100
pF1KE3 LDPATEARYRREGARFIFDVGTRLGLHYDTLATGIIYFHRFYMFHSFKQFPRYVTGACCL
:: .:. : : ..: .: : : ..::: . ::::.. .:: . ... :.
NP_001 LDLPSETDLRILGCELIQAAGILLRLPQVAMATGQVLFHRFFYSKSFVKHSFEIVAMACI
80 90 100 110 120 130
110 120 130 140 150
pF1KE3 FLAGKIEETPKKCKDIIKTARSLL--------NDVQFGQFGDDPKEEVMVLERILLQTIK
::.::::.:.. .:.:.. . : . . . : . :..:. :: .:. .
NP_001 NLASKIEEAPRRIRDVINVFHHLRQLRGKRTPSPLILDQNYINTKNQVIKAERRVLKELG
140 150 160 170 180 190
160 170 180 190 200 210
pF1KE3 FDLQVEHPYQFLLKYAKQLKGDKNKIQKLVQMAWTFVNDSLCTTLSLQWEPEIIAVAVMY
: ..:.::..... : . :. ..: : ::: ::...:::: :.. ....:: :: : .:
NP_001 FCVHVKHPHKIIVMYLQVLECERN--QTLVQTAWNYMNDSLRTNVFVRFQPETIACACIY
200 210 220 230 240 250
220 230 240 250 260
pF1KE3 LAGRLCKFEIQEWTSKPMYRRWWEQFVQDVPVDVLEDICHQILDLYSQGK---QQMPHHT
::.: .. . : .:. : . . ...:: . : ::.. : . . ...
NP_001 LAARALQIPL------PTRPHWFLLF--GTTEEEIQEICIETLRLYTRKKPNYELLEKEV
260 270 280 290 300
270 280 290 300 310 320
pF1KE3 PHQ---LQQPP----SLQP--TPQVPQVQQSQPSQSSEPSQPQQKDPLILLQGWACRQPA
.. ::. .:.: :: . . .:. :.::.:..
NP_001 EKRKVALQEAKLKAKGLNPDGTPALSTLGGFSPA--SKPSSPREVKAEEKSPISINVKTV
310 320 330 340 350 360
330 340 350
pF1KE3 THLLPSPLEDSLLCPRPFPHPACLQLGGWGGQPG
NP_001 KKEPEDRQQASKSPYNGVRKDSKRSRNSRSASRSRSRTRSRSRSHTPRRQDEVLLRCPGR
370 380 390 400 410 420
>>XP_006713773 (OMIM: 613384) PREDICTED: cyclin-L1 isofo (493 aa)
initn: 399 init1: 197 opt: 392 Z-score: 289.7 bits: 62.6 E(85289): 2.1e-09
Smith-Waterman score: 395; 29.0% identity (60.2% similar) in 314 aa overlap (11-304:48-345)
10 20 30 40
pF1KE3 MKENKENSSPSVTSANLDHTKPCWYWDKKDLAHTPSQLEG
: .: ..::. .. :. :::. .:
XP_006 AAPSAGGSSSGTTTTTTTTTGGILIGDRLYSEVSLTIDHS----LIPEERLSPTPSMQDG
20 30 40 50 60 70
50 60 70 80 90 100
pF1KE3 LDPATEARYRREGARFIFDVGTRLGLHYDTLATGIIYFHRFYMFHSFKQFPRYVTGACCL
:: .:. : : ..: .: : : ..::: . ::::.. .:: . ... :.
XP_006 LDLPSETDLRILGCELIQAAGILLRLPQVAMATGQVLFHRFFYSKSFVKHSFEIVAMACI
80 90 100 110 120 130
110 120 130 140 150
pF1KE3 FLAGKIEETPKKCKDIIKTARSLL--------NDVQFGQFGDDPKEEVMVLERILLQTIK
::.::::.:.. .:.:.. . : . . . : . :..:. :: .:. .
XP_006 NLASKIEEAPRRIRDVINVFHHLRQLRGKRTPSPLILDQNYINTKNQVIKAERRVLKELG
140 150 160 170 180 190
160 170 180 190 200 210
pF1KE3 FDLQVEHPYQFLLKYAKQLKGDKNKIQKLVQMAWTFVNDSLCTTLSLQWEPEIIAVAVMY
: ..:.::..... : . :. ..: : ::: ::...:::: :.. ....:: :: : .:
XP_006 FCVHVKHPHKIIVMYLQVLECERN--QTLVQTAWNYMNDSLRTNVFVRFQPETIACACIY
200 210 220 230 240 250
220 230 240 250 260
pF1KE3 LAGRLCKFEIQEWTSKPMYRRWWEQFVQDVPVDVLEDICHQILDLYSQGK---QQMPHHT
::.: .. . : .:. : . . ...:: . : ::.. : . . ...
XP_006 LAARALQIPL------PTRPHWFLLF--GTTEEEIQEICIETLRLYTRKKPNYELLEKEV
260 270 280 290 300
270 280 290 300 310 320
pF1KE3 PHQ---LQQPP----SLQP--TPQVPQVQQSQPSQSSEPSQPQQKDPLILLQGWACRQPA
.. ::. .:.: :: . . .:. :.::.:..
XP_006 EKRKVALQEAKLKAKGLNPDGTPALSTLGGFSPA--SKPSSPREVKAEEKSPISINVKTV
310 320 330 340 350 360
330 340 350
pF1KE3 THLLPSPLEDSLLCPRPFPHPACLQLGGWGGQPG
XP_006 KKEPEDRQQASKSPYNGYNNRRSRSGTYSSRSRSRSRSHSESPRRHHNHGSPHLKAKHTR
370 380 390 400 410 420
>>NP_064703 (OMIM: 613384) cyclin-L1 isoform 1 [Homo sap (526 aa)
initn: 399 init1: 197 opt: 392 Z-score: 289.3 bits: 62.6 E(85289): 2.2e-09
Smith-Waterman score: 395; 29.0% identity (60.2% similar) in 314 aa overlap (11-304:48-345)
10 20 30 40
pF1KE3 MKENKENSSPSVTSANLDHTKPCWYWDKKDLAHTPSQLEG
: .: ..::. .. :. :::. .:
NP_064 AAPSAGGSSSGTTTTTTTTTGGILIGDRLYSEVSLTIDHS----LIPEERLSPTPSMQDG
20 30 40 50 60 70
50 60 70 80 90 100
pF1KE3 LDPATEARYRREGARFIFDVGTRLGLHYDTLATGIIYFHRFYMFHSFKQFPRYVTGACCL
:: .:. : : ..: .: : : ..::: . ::::.. .:: . ... :.
NP_064 LDLPSETDLRILGCELIQAAGILLRLPQVAMATGQVLFHRFFYSKSFVKHSFEIVAMACI
80 90 100 110 120 130
110 120 130 140 150
pF1KE3 FLAGKIEETPKKCKDIIKTARSLL--------NDVQFGQFGDDPKEEVMVLERILLQTIK
::.::::.:.. .:.:.. . : . . . : . :..:. :: .:. .
NP_064 NLASKIEEAPRRIRDVINVFHHLRQLRGKRTPSPLILDQNYINTKNQVIKAERRVLKELG
140 150 160 170 180 190
160 170 180 190 200 210
pF1KE3 FDLQVEHPYQFLLKYAKQLKGDKNKIQKLVQMAWTFVNDSLCTTLSLQWEPEIIAVAVMY
: ..:.::..... : . :. ..: : ::: ::...:::: :.. ....:: :: : .:
NP_064 FCVHVKHPHKIIVMYLQVLECERN--QTLVQTAWNYMNDSLRTNVFVRFQPETIACACIY
200 210 220 230 240 250
220 230 240 250 260
pF1KE3 LAGRLCKFEIQEWTSKPMYRRWWEQFVQDVPVDVLEDICHQILDLYSQGK---QQMPHHT
::.: .. . : .:. : . . ...:: . : ::.. : . . ...
NP_064 LAARALQIPL------PTRPHWFLLF--GTTEEEIQEICIETLRLYTRKKPNYELLEKEV
260 270 280 290 300
270 280 290 300 310 320
pF1KE3 PHQ---LQQPP----SLQP--TPQVPQVQQSQPSQSSEPSQPQQKDPLILLQGWACRQPA
.. ::. .:.: :: . . .:. :.::.:..
NP_064 EKRKVALQEAKLKAKGLNPDGTPALSTLGGFSPA--SKPSSPREVKAEEKSPISINVKTV
310 320 330 340 350 360
330 340 350
pF1KE3 THLLPSPLEDSLLCPRPFPHPACLQLGGWGGQPG
NP_064 KKEPEDRQQASKSPYNGVRKDSKRSRNSRSASRSRSRTRSRSRSHTPRRHYNNRRSRSGT
370 380 390 400 410 420
354 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 03:18:53 2016 done: Mon Nov 7 03:18:54 2016
Total Scan time: 8.570 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]