Result of FASTA (omim) for
pFN21AE3593
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3593, 153 aa
1>>>pF1KE3593 153 - 153 aa - 153 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.2974+/-0.000262; mu= 12.5004+/- 0.017
mean_var=70.7032+/-14.301, 0's: 0 Z-trim(121.2): 112 B-trim: 1463 in 2/54
Lambda= 0.152530
statistics sampled from 37254 (37382) to 37254 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.808), E-opt: 0.2 (0.438), width: 16
Scan time: 5.640
The best scores are: opt bits E(85289)
NP_004214 (OMIM: 603890) ubiquitin/ISG15-conjugati ( 153) 1057 240.5 7.9e-64
NP_937826 (OMIM: 603890) ubiquitin/ISG15-conjugati ( 87) 592 138.0 3.2e-33
NP_003338 (OMIM: 603721) ubiquitin-conjugating enz ( 154) 594 138.6 3.7e-33
NP_001243284 (OMIM: 603721) ubiquitin-conjugating ( 212) 566 132.6 3.4e-31
NP_001243285 (OMIM: 603721) ubiquitin-conjugating ( 122) 478 113.0 1.5e-25
XP_016884424 (OMIM: 603721) PREDICTED: ubiquitin-c ( 121) 457 108.4 3.6e-24
NP_003329 (OMIM: 602961) ubiquitin-conjugating enz ( 147) 375 90.4 1.1e-18
NP_003330 (OMIM: 602962) ubiquitin-conjugating enz ( 147) 359 86.9 1.3e-17
NP_871621 (OMIM: 602963) ubiquitin-conjugating enz ( 148) 353 85.6 3.3e-17
NP_871618 (OMIM: 602963) ubiquitin-conjugating enz ( 147) 351 85.2 4.5e-17
NP_871620 (OMIM: 602963) ubiquitin-conjugating enz ( 147) 351 85.2 4.5e-17
NP_871617 (OMIM: 602963) ubiquitin-conjugating enz ( 147) 351 85.2 4.5e-17
NP_871619 (OMIM: 602963) ubiquitin-conjugating enz ( 147) 351 85.2 4.5e-17
NP_871615 (OMIM: 602963) ubiquitin-conjugating enz ( 147) 351 85.2 4.5e-17
NP_871616 (OMIM: 602963) ubiquitin-conjugating enz ( 147) 351 85.2 4.5e-17
NP_003331 (OMIM: 602963) ubiquitin-conjugating enz ( 147) 351 85.2 4.5e-17
XP_016865309 (OMIM: 602962) PREDICTED: ubiquitin-c ( 173) 339 82.6 3.2e-16
NP_871622 (OMIM: 602963) ubiquitin-conjugating enz ( 149) 337 82.1 3.8e-16
NP_003327 (OMIM: 300860,312180) ubiquitin-conjugat ( 152) 314 77.0 1.3e-14
NP_054895 (OMIM: 610538,616435) ubiquitin-conjugat ( 197) 315 77.3 1.4e-14
NP_862821 (OMIM: 602962) ubiquitin-conjugating enz ( 118) 312 76.5 1.4e-14
NP_001191809 (OMIM: 602961) ubiquitin-conjugating ( 109) 304 74.7 4.6e-14
XP_016872098 (OMIM: 602961) PREDICTED: ubiquitin-c ( 110) 304 74.7 4.6e-14
XP_016864073 (OMIM: 602963) PREDICTED: ubiquitin-c ( 118) 304 74.7 4.9e-14
NP_001287724 (OMIM: 602963) ubiquitin-conjugating ( 118) 304 74.7 4.9e-14
NP_003328 (OMIM: 179095) ubiquitin-conjugating enz ( 152) 301 74.2 9.4e-14
NP_003339 (OMIM: 603679) ubiquitin-conjugating enz ( 152) 297 73.3 1.7e-13
NP_001189405 (OMIM: 602916) ubiquitin-conjugating ( 160) 293 72.4 3.3e-13
NP_003332 (OMIM: 602916) ubiquitin-conjugating enz ( 193) 293 72.5 3.9e-13
XP_005265489 (OMIM: 602163) PREDICTED: ubiquitin-c ( 201) 283 70.3 1.8e-12
NP_689866 (OMIM: 602163) ubiquitin-conjugating enz ( 201) 283 70.3 1.8e-12
NP_001297255 (OMIM: 610538,616435) ubiquitin-conju ( 167) 279 69.3 2.9e-12
NP_001265484 (OMIM: 604151) ubiquitin-conjugating ( 207) 271 67.6 1.2e-11
NP_001265483 (OMIM: 604151) ubiquitin-conjugating ( 207) 271 67.6 1.2e-11
NP_872619 (OMIM: 604151) ubiquitin-conjugating enz ( 207) 271 67.6 1.2e-11
XP_005246301 (OMIM: 604151) PREDICTED: ubiquitin-c ( 207) 271 67.6 1.2e-11
NP_006348 (OMIM: 604151) ubiquitin-conjugating enz ( 207) 271 67.6 1.2e-11
NP_003960 (OMIM: 603173) NEDD8-conjugating enzyme ( 183) 270 67.4 1.2e-11
XP_005265488 (OMIM: 602916) PREDICTED: ubiquitin-c ( 167) 267 66.7 1.8e-11
NP_001269090 (OMIM: 300860,312180) ubiquitin-conju ( 119) 265 66.2 1.9e-11
XP_005265490 (OMIM: 602163) PREDICTED: ubiquitin-c ( 189) 257 64.5 9.2e-11
NP_872607 (OMIM: 602916) ubiquitin-conjugating enz ( 176) 250 63.0 2.5e-10
NP_003335 (OMIM: 601082) ubiquitin-conjugating enz ( 183) 250 63.0 2.6e-10
NP_005330 (OMIM: 602846) ubiquitin-conjugating enz ( 200) 240 60.8 1.3e-09
NP_919236 (OMIM: 601661) SUMO-conjugating enzyme U ( 158) 232 59.0 3.6e-09
XP_016879129 (OMIM: 601661) PREDICTED: SUMO-conjug ( 158) 232 59.0 3.6e-09
NP_003336 (OMIM: 601661) SUMO-conjugating enzyme U ( 158) 232 59.0 3.6e-09
NP_919237 (OMIM: 601661) SUMO-conjugating enzyme U ( 158) 232 59.0 3.6e-09
NP_919235 (OMIM: 601661) SUMO-conjugating enzyme U ( 158) 232 59.0 3.6e-09
NP_861517 (OMIM: 605574) ubiquitin-conjugating enz ( 140) 231 58.7 3.8e-09
>>NP_004214 (OMIM: 603890) ubiquitin/ISG15-conjugating e (153 aa)
initn: 1057 init1: 1057 opt: 1057 Z-score: 1266.9 bits: 240.5 E(85289): 7.9e-64
Smith-Waterman score: 1057; 100.0% identity (100.0% similar) in 153 aa overlap (1-153:1-153)
10 20 30 40 50 60
pF1KE3 MMASMRVVKELEDLQKKPPPYLRNLSSDDANVLVWHALLLPDQPPYHLKAFNLRISFPPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MMASMRVVKELEDLQKKPPPYLRNLSSDDANVLVWHALLLPDQPPYHLKAFNLRISFPPE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 YPFKPPMIKFTTKIYHPNVDENGQICLPIISSENWKPCTKTCQVLEALNVLVNRPNIREP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 YPFKPPMIKFTTKIYHPNVDENGQICLPIISSENWKPCTKTCQVLEALNVLVNRPNIREP
70 80 90 100 110 120
130 140 150
pF1KE3 LRMDLADLLTQNPELFRKNAEEFTLRFGVDRPS
:::::::::::::::::::::::::::::::::
NP_004 LRMDLADLLTQNPELFRKNAEEFTLRFGVDRPS
130 140 150
>>NP_937826 (OMIM: 603890) ubiquitin/ISG15-conjugating e (87 aa)
initn: 592 init1: 592 opt: 592 Z-score: 717.5 bits: 138.0 E(85289): 3.2e-33
Smith-Waterman score: 592; 100.0% identity (100.0% similar) in 87 aa overlap (67-153:1-87)
40 50 60 70 80 90
pF1KE3 ALLLPDQPPYHLKAFNLRISFPPEYPFKPPMIKFTTKIYHPNVDENGQICLPIISSENWK
::::::::::::::::::::::::::::::
NP_937 MIKFTTKIYHPNVDENGQICLPIISSENWK
10 20 30
100 110 120 130 140 150
pF1KE3 PCTKTCQVLEALNVLVNRPNIREPLRMDLADLLTQNPELFRKNAEEFTLRFGVDRPS
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_937 PCTKTCQVLEALNVLVNRPNIREPLRMDLADLLTQNPELFRKNAEEFTLRFGVDRPS
40 50 60 70 80
>>NP_003338 (OMIM: 603721) ubiquitin-conjugating enzyme (154 aa)
initn: 594 init1: 594 opt: 594 Z-score: 716.3 bits: 138.6 E(85289): 3.7e-33
Smith-Waterman score: 594; 55.3% identity (80.3% similar) in 152 aa overlap (1-152:1-152)
10 20 30 40 50 60
pF1KE3 MMASMRVVKELEDLQKKPPPYLRNLSSDDANVLVWHALLLPDQPPYHLKAFNLRISFPPE
: :: :..::::...: .::.. :.::.:.:..:..::.::: :: ..:.:: :
NP_003 MAASRRLMKELEEIRKCGMKNFRNIQVDEANLLTWQGLIVPDNPPYDKGAFRIEINFPAE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 YPFKPPMIKFTTKIYHPNVDENGQICLPIISSENWKPCTKTCQVLEALNVLVNRPNIREP
:::::: : : :::::::.::.::.:::.::.::::: ::: ::...: .::: :. ..:
NP_003 YPFKPPKITFKTKIYHPNIDEKGQVCLPVISAENWKPATKTDQVIQSLIALVNDPQPEHP
70 80 90 100 110 120
130 140 150
pF1KE3 LRMDLADLLTQNPELFRKNAEEFTLRFGVDRPS
:: :::. ... . : ::::::: ..: ::
NP_003 LRADLAEEYSKDRKKFCKNAEEFTKKYGEKRPVD
130 140 150
>>NP_001243284 (OMIM: 603721) ubiquitin-conjugating enzy (212 aa)
initn: 566 init1: 566 opt: 566 Z-score: 680.9 bits: 132.6 E(85289): 3.4e-31
Smith-Waterman score: 566; 54.9% identity (80.6% similar) in 144 aa overlap (9-152:67-210)
10 20 30
pF1KE3 MMASMRVVKELEDLQKKPPPYLRNLSSDDANVLVWHAL
.:::...: .::.. :.::.:.:..:
NP_001 RQVPSALAGKDLAQLQAGATLAGYRRAHGPEELEEIRKCGMKNFRNIQVDEANLLTWQGL
40 50 60 70 80 90
40 50 60 70 80 90
pF1KE3 LLPDQPPYHLKAFNLRISFPPEYPFKPPMIKFTTKIYHPNVDENGQICLPIISSENWKPC
..::.::: :: ..:.:: ::::::: : : :::::::.::.::.:::.::.:::::
NP_001 IVPDNPPYDKGAFRIEINFPAEYPFKPPKITFKTKIYHPNIDEKGQVCLPVISAENWKPA
100 110 120 130 140 150
100 110 120 130 140 150
pF1KE3 TKTCQVLEALNVLVNRPNIREPLRMDLADLLTQNPELFRKNAEEFTLRFGVDRPS
::: ::...: .::: :. ..::: :::. ... . : ::::::: ..: ::
NP_001 TKTDQVIQSLIALVNDPQPEHPLRADLAEEYSKDRKKFCKNAEEFTKKYGEKRPVD
160 170 180 190 200 210
>>NP_001243285 (OMIM: 603721) ubiquitin-conjugating enzy (122 aa)
initn: 478 init1: 478 opt: 478 Z-score: 579.8 bits: 113.0 E(85289): 1.5e-25
Smith-Waterman score: 478; 58.8% identity (79.8% similar) in 114 aa overlap (39-152:7-120)
10 20 30 40 50 60
pF1KE3 KELEDLQKKPPPYLRNLSSDDANVLVWHALLLPDQPPYHLKAFNLRISFPPEYPFKPPMI
:. :.::: :: ..:.:: ::::::: :
NP_001 MAASRRLMKDNPPYDKGAFRIEINFPAEYPFKPPKI
10 20 30
70 80 90 100 110 120
pF1KE3 KFTTKIYHPNVDENGQICLPIISSENWKPCTKTCQVLEALNVLVNRPNIREPLRMDLADL
: :::::::.::.::.:::.::.::::: ::: ::...: .::: :. ..::: :::.
NP_001 TFKTKIYHPNIDEKGQVCLPVISAENWKPATKTDQVIQSLIALVNDPQPEHPLRADLAEE
40 50 60 70 80 90
130 140 150
pF1KE3 LTQNPELFRKNAEEFTLRFGVDRPS
... . : ::::::: ..: ::
NP_001 YSKDRKKFCKNAEEFTKKYGEKRPVD
100 110 120
>>XP_016884424 (OMIM: 603721) PREDICTED: ubiquitin-conju (121 aa)
initn: 477 init1: 444 opt: 457 Z-score: 554.8 bits: 108.4 E(85289): 3.6e-24
Smith-Waterman score: 457; 54.9% identity (80.5% similar) in 113 aa overlap (1-113:1-113)
10 20 30 40 50 60
pF1KE3 MMASMRVVKELEDLQKKPPPYLRNLSSDDANVLVWHALLLPDQPPYHLKAFNLRISFPPE
: :: :..::::...: .::.. :.::.:.:..:..::.::: :: ..:.:: :
XP_016 MAASRRLMKELEEIRKCGMKNFRNIQVDEANLLTWQGLIVPDNPPYDKGAFRIEINFPAE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 YPFKPPMIKFTTKIYHPNVDENGQICLPIISSENWKPCTKTCQVLEALNVLVNRPNIREP
:::::: : : :::::::.::.::.:::.::.::::: ::: : :. ....
XP_016 YPFKPPKITFKTKIYHPNIDEKGQVCLPVISAENWKPATKTDQETSAFPIMASLRSSLEV
70 80 90 100 110 120
130 140 150
pF1KE3 LRMDLADLLTQNPELFRKNAEEFTLRFGVDRPS
XP_016 L
>>NP_003329 (OMIM: 602961) ubiquitin-conjugating enzyme (147 aa)
initn: 326 init1: 268 opt: 375 Z-score: 456.1 bits: 90.4 E(85289): 1.1e-18
Smith-Waterman score: 375; 38.9% identity (65.8% similar) in 149 aa overlap (2-149:1-147)
10 20 30 40 50
pF1KE3 MMASMRVVKELEDLQKKPPPYLRNLSSDDANVLVWHALLL-PDQPPYHLKAFNLRISFPP
:: :. ::: :::. :: . : ... :.: .. : . :. .: : . ::
NP_003 MALKRIQKELSDLQRDPPAHCSAGPVGD-DLFHWQATIMGPPDSAYQGGVFFLTVHFPT
10 20 30 40 50
60 70 80 90 100 110
pF1KE3 EYPFKPPMIKFTTKIYHPNVDENGQICLPIISSENWKPCTKTCQVLEALNVLVNRPNIRE
.:::::: : :::::::::.. ::.::: :. :. :.: . .:: .. :. :: .
NP_003 DYPFKPPKIAFTTKIYHPNINSNGSICLDILRSQ-WSPALTVSKVLLSICSLLCDPNPDD
60 70 80 90 100 110
120 130 140 150
pF1KE3 PLRMDLADLLTQNPELFRKNAEEFTLRFGVDRPS
:: :.:.. .. : . ..:.:.: ....
NP_003 PLVPDIAQIYKSDKEKYNRHAREWTQKYAM
120 130 140
>>NP_003330 (OMIM: 602962) ubiquitin-conjugating enzyme (147 aa)
initn: 324 init1: 270 opt: 359 Z-score: 437.1 bits: 86.9 E(85289): 1.3e-17
Smith-Waterman score: 359; 37.6% identity (63.8% similar) in 149 aa overlap (2-149:1-147)
10 20 30 40 50
pF1KE3 MMASMRVVKELEDLQKKPPPYLRNLSSDDANVLVWHALLL-PDQPPYHLKAFNLRISFPP
:: :. :::.:: . :: : ... :.: .. :.. ::. .: : : ::
NP_003 MALKRIHKELNDLARDPPAQCSAGPVGD-DMFHWQATIMGPNDSPYQGGVFFLTIHFPT
10 20 30 40 50
60 70 80 90 100 110
pF1KE3 EYPFKPPMIKFTTKIYHPNVDENGQICLPIISSENWKPCTKTCQVLEALNVLVNRPNIRE
.:::::: . :::.:::::.. ::.::: :. :. :.: .:: .. :. :: .
NP_003 DYPFKPPKVAFTTRIYHPNINSNGSICLDILRSQ-WSPALTISKVLLSICSLLCDPNPDD
60 70 80 90 100 110
120 130 140 150
pF1KE3 PLRMDLADLLTQNPELFRKNAEEFTLRFGVDRPS
:: ..: . . : . . :.:.: ....
NP_003 PLVPEIARIYKTDREKYNRIAREWTQKYAM
120 130 140
>>NP_871621 (OMIM: 602963) ubiquitin-conjugating enzyme (148 aa)
initn: 324 init1: 270 opt: 353 Z-score: 429.9 bits: 85.6 E(85289): 3.3e-17
Smith-Waterman score: 353; 36.9% identity (63.1% similar) in 149 aa overlap (2-149:1-147)
10 20 30 40 50
pF1KE3 MMASMRVVKELEDLQKKPPPYLRNLSSDDANVLVWHALLL-PDQPPYHLKAFNLRISFPP
:: :. ::: :: . :: : ... :.: .. :.. ::. .: : : ::
NP_871 MALKRINKELSDLARDPPAQCSAGPVGD-DMFHWQATIMGPNDSPYQGGVFFLTIHFPT
10 20 30 40 50
60 70 80 90 100 110
pF1KE3 EYPFKPPMIKFTTKIYHPNVDENGQICLPIISSENWKPCTKTCQVLEALNVLVNRPNIRE
.:::::: . :::.:::::.. ::.::: :. :. :.: .:: .. :. :: .
NP_871 DYPFKPPKVAFTTRIYHPNINSNGSICLDILRSQ-WSPALTISKVLLSICSLLCDPNPDD
60 70 80 90 100 110
120 130 140 150
pF1KE3 PLRMDLADLLTQNPELFRKNAEEFTLRFGVDRPS
:: ..: . . . . . :.:.: ....
NP_871 PLVPEIARIYKTDRDKYNRLAREWTEKYAML
120 130 140
>>NP_871618 (OMIM: 602963) ubiquitin-conjugating enzyme (147 aa)
initn: 324 init1: 270 opt: 351 Z-score: 427.6 bits: 85.2 E(85289): 4.5e-17
Smith-Waterman score: 351; 36.2% identity (63.1% similar) in 149 aa overlap (2-149:1-147)
10 20 30 40 50
pF1KE3 MMASMRVVKELEDLQKKPPPYLRNLSSDDANVLVWHALLL-PDQPPYHLKAFNLRISFPP
:: :. ::: :: . :: : ... :.: .. :.. ::. .: : : ::
NP_871 MALKRINKELSDLARDPPAQCSAGPVGD-DMFHWQATIMGPNDSPYQGGVFFLTIHFPT
10 20 30 40 50
60 70 80 90 100 110
pF1KE3 EYPFKPPMIKFTTKIYHPNVDENGQICLPIISSENWKPCTKTCQVLEALNVLVNRPNIRE
.:::::: . :::.:::::.. ::.::: :. :. :.: .:: .. :. :: .
NP_871 DYPFKPPKVAFTTRIYHPNINSNGSICLDILRSQ-WSPALTISKVLLSICSLLCDPNPDD
60 70 80 90 100 110
120 130 140 150
pF1KE3 PLRMDLADLLTQNPELFRKNAEEFTLRFGVDRPS
:: ..: . . . . . ..:.: ....
NP_871 PLVPEIARIYKTDRDKYNRISREWTQKYAM
120 130 140
153 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 22:23:15 2016 done: Sun Nov 6 22:23:15 2016
Total Scan time: 5.640 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]