Result of FASTA (ccds) for
pFN21AE3589
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3589, 227 aa
1>>>pF1KE3589 227 - 227 aa - 227 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.5833+/-0.000811; mu= 12.4429+/- 0.049
mean_var=65.4275+/-13.013, 0's: 0 Z-trim(106.9): 28 B-trim: 5 in 1/49
Lambda= 0.158560
statistics sampled from 9250 (9274) to 9250 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.671), E-opt: 0.2 (0.285), width: 16
Scan time: 2.160
The best scores are: opt bits E(32554)
CCDS6455.1 AK3 gene_id:50808|Hs108|chr9 ( 227) 1485 348.2 2.5e-96
CCDS56561.1 AK3 gene_id:50808|Hs108|chr9 ( 157) 1041 246.6 6.8e-66
CCDS56562.1 AK3 gene_id:50808|Hs108|chr9 ( 187) 929 221.0 4.1e-58
CCDS629.1 AK4 gene_id:205|Hs108|chr1 ( 223) 926 220.3 7.7e-58
CCDS81340.1 AK4 gene_id:205|Hs108|chr1 ( 171) 730 175.5 1.9e-44
CCDS81296.1 AK2 gene_id:204|Hs108|chr1 ( 232) 580 141.2 5.3e-34
CCDS373.1 AK2 gene_id:204|Hs108|chr1 ( 232) 580 141.2 5.3e-34
CCDS374.1 AK2 gene_id:204|Hs108|chr1 ( 239) 580 141.2 5.5e-34
CCDS81294.1 AK2 gene_id:204|Hs108|chr1 ( 190) 406 101.4 4.3e-22
CCDS6954.1 AK8 gene_id:158067|Hs108|chr9 ( 479) 307 78.9 6.4e-15
CCDS81295.1 AK2 gene_id:204|Hs108|chr1 ( 133) 276 71.6 2.8e-13
>>CCDS6455.1 AK3 gene_id:50808|Hs108|chr9 (227 aa)
initn: 1485 init1: 1485 opt: 1485 Z-score: 1842.9 bits: 348.2 E(32554): 2.5e-96
Smith-Waterman score: 1485; 100.0% identity (100.0% similar) in 227 aa overlap (1-227:1-227)
10 20 30 40 50 60
pF1KE3 MGASARLLRAVIMGAPGSGKGTVSSRITTHFELKHLSSGDLLRDNMLRGTEIGVLAKAFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS64 MGASARLLRAVIMGAPGSGKGTVSSRITTHFELKHLSSGDLLRDNMLRGTEIGVLAKAFI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 DQGKLIPDDVMTRLALHELKNLTQYSWLLDGFPRTLPQAEALDRAYQIDTVINLNVPFEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS64 DQGKLIPDDVMTRLALHELKNLTQYSWLLDGFPRTLPQAEALDRAYQIDTVINLNVPFEV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 IKQRLTARWIHPASGRVYNIEFNPPKTVGIDDLTGEPLIQREDDKPETVIKRLKAYEDQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS64 IKQRLTARWIHPASGRVYNIEFNPPKTVGIDDLTGEPLIQREDDKPETVIKRLKAYEDQT
130 140 150 160 170 180
190 200 210 220
pF1KE3 KPVLEYYQKKGVLETFSGTETNKIWPYVYAFLQTKVPQRSQKASVTP
:::::::::::::::::::::::::::::::::::::::::::::::
CCDS64 KPVLEYYQKKGVLETFSGTETNKIWPYVYAFLQTKVPQRSQKASVTP
190 200 210 220
>>CCDS56561.1 AK3 gene_id:50808|Hs108|chr9 (157 aa)
initn: 1041 init1: 1041 opt: 1041 Z-score: 1296.5 bits: 246.6 E(32554): 6.8e-66
Smith-Waterman score: 1041; 100.0% identity (100.0% similar) in 157 aa overlap (71-227:1-157)
50 60 70 80 90 100
pF1KE3 LLRDNMLRGTEIGVLAKAFIDQGKLIPDDVMTRLALHELKNLTQYSWLLDGFPRTLPQAE
::::::::::::::::::::::::::::::
CCDS56 MTRLALHELKNLTQYSWLLDGFPRTLPQAE
10 20 30
110 120 130 140 150 160
pF1KE3 ALDRAYQIDTVINLNVPFEVIKQRLTARWIHPASGRVYNIEFNPPKTVGIDDLTGEPLIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 ALDRAYQIDTVINLNVPFEVIKQRLTARWIHPASGRVYNIEFNPPKTVGIDDLTGEPLIQ
40 50 60 70 80 90
170 180 190 200 210 220
pF1KE3 REDDKPETVIKRLKAYEDQTKPVLEYYQKKGVLETFSGTETNKIWPYVYAFLQTKVPQRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 REDDKPETVIKRLKAYEDQTKPVLEYYQKKGVLETFSGTETNKIWPYVYAFLQTKVPQRS
100 110 120 130 140 150
pF1KE3 QKASVTP
:::::::
CCDS56 QKASVTP
>>CCDS56562.1 AK3 gene_id:50808|Hs108|chr9 (187 aa)
initn: 1212 init1: 910 opt: 929 Z-score: 1156.8 bits: 221.0 E(32554): 4.1e-58
Smith-Waterman score: 1136; 82.4% identity (82.4% similar) in 227 aa overlap (1-227:1-187)
10 20 30 40 50 60
pF1KE3 MGASARLLRAVIMGAPGSGKGTVSSRITTHFELKHLSSGDLLRDNMLRGTEIGVLAKAFI
::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 MGASARLLRAVIMGAPGSGKGTVSSRITTHFELKHLSSGDLLRDNMLRGT----------
10 20 30 40 50
70 80 90 100 110 120
pF1KE3 DQGKLIPDDVMTRLALHELKNLTQYSWLLDGFPRTLPQAEALDRAYQIDTVINLNVPFEV
::::::::::::::::::::::::::::::
CCDS56 ------------------------------GFPRTLPQAEALDRAYQIDTVINLNVPFEV
60 70 80
130 140 150 160 170 180
pF1KE3 IKQRLTARWIHPASGRVYNIEFNPPKTVGIDDLTGEPLIQREDDKPETVIKRLKAYEDQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 IKQRLTARWIHPASGRVYNIEFNPPKTVGIDDLTGEPLIQREDDKPETVIKRLKAYEDQT
90 100 110 120 130 140
190 200 210 220
pF1KE3 KPVLEYYQKKGVLETFSGTETNKIWPYVYAFLQTKVPQRSQKASVTP
:::::::::::::::::::::::::::::::::::::::::::::::
CCDS56 KPVLEYYQKKGVLETFSGTETNKIWPYVYAFLQTKVPQRSQKASVTP
150 160 170 180
>>CCDS629.1 AK4 gene_id:205|Hs108|chr1 (223 aa)
initn: 931 init1: 912 opt: 926 Z-score: 1151.9 bits: 220.3 E(32554): 7.7e-58
Smith-Waterman score: 926; 59.7% identity (85.1% similar) in 221 aa overlap (4-223:2-222)
10 20 30 40 50 60
pF1KE3 MGASARLLRAVIMGAPGSGKGTVSSRITTHFELKHLSSGDLLRDNMLRGTEIGVLAKAFI
...::::::.: :::::::: .::. .: :.::::: .::.:. .::.: .:: .:
CCDS62 MASKLLRAVILGPPGSGKGTVCQRIAQNFGLQHLSSGHFLRENIKASTEVGEMAKQYI
10 20 30 40 50
70 80 90 100 110 120
pF1KE3 DQGKLIPDDVMTRLALHELKNLTQYSWLLDGFPRTLPQAEALDRAYQIDTVINLNVPFEV
... :.:: :.::: . ::.: :::::::::: ::::::. ..: ::.::.:::.
CCDS62 EKSLLVPDHVITRLMMSELENRRGQHWLLDGFPRTLGQAEALDKICEVDLVISLNIPFET
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE3 IKQRLTARWIHPASGRVYNIEFNPPKTVGIDDLTGEPLIQREDDKPETVIKRLKAYEDQT
.:.::. ::::: ::::::..::::.. ::::.:::::.:.::::::.: ::. :.: .
CCDS62 LKDRLSRRWIHPPSGRVYNLDFNPPHVHGIDDVTGEPLVQQEDDKPEAVAARLRQYKDVA
120 130 140 150 160 170
190 200 210 220
pF1KE3 KPVLEYYQKKGVLETFSGTETNKIWPYVYAFLQTKV-PQRSQKASVTP
:::.: :...:::. ::::::::::::::.....:. : .:..:
CCDS62 KPVIELYKSRGVLHQFSGTETNKIWPYVYTLFSNKITPIQSKEAY
180 190 200 210 220
>>CCDS81340.1 AK4 gene_id:205|Hs108|chr1 (171 aa)
initn: 737 init1: 718 opt: 730 Z-score: 911.4 bits: 175.5 E(32554): 1.9e-44
Smith-Waterman score: 730; 60.0% identity (85.3% similar) in 170 aa overlap (55-223:1-170)
30 40 50 60 70 80
pF1KE3 SRITTHFELKHLSSGDLLRDNMLRGTEIGVLAKAFIDQGKLIPDDVMTRLALHELKNLTQ
.:: .:... :.:: :.::: . ::.:
CCDS81 MAKQYIEKSLLVPDHVITRLMMSELENRRG
10 20 30
90 100 110 120 130 140
pF1KE3 YSWLLDGFPRTLPQAEALDRAYQIDTVINLNVPFEVIKQRLTARWIHPASGRVYNIEFNP
:::::::::: ::::::. ..: ::.::.:::..:.::. ::::: ::::::..:::
CCDS81 QHWLLDGFPRTLGQAEALDKICEVDLVISLNIPFETLKDRLSRRWIHPPSGRVYNLDFNP
40 50 60 70 80 90
150 160 170 180 190 200
pF1KE3 PKTVGIDDLTGEPLIQREDDKPETVIKRLKAYEDQTKPVLEYYQKKGVLETFSGTETNKI
:.. ::::.:::::.:.::::::.: ::. :.: .:::.: :...:::. :::::::::
CCDS81 PHVHGIDDVTGEPLVQQEDDKPEAVAARLRQYKDVAKPVIELYKSRGVLHQFSGTETNKI
100 110 120 130 140 150
210 220
pF1KE3 WPYVYAFLQTKV-PQRSQKASVTP
:::::.....:. : .:..:
CCDS81 WPYVYTLFSNKITPIQSKEAY
160 170
>>CCDS81296.1 AK2 gene_id:204|Hs108|chr1 (232 aa)
initn: 613 init1: 299 opt: 580 Z-score: 723.9 bits: 141.2 E(32554): 5.3e-34
Smith-Waterman score: 580; 43.8% identity (74.9% similar) in 203 aa overlap (8-204:16-218)
10 20 30 40 50
pF1KE3 MGASARLLRAVIMGAPGSGKGTVSSRITTHFELKHLSSGDLLRDNMLRGTEI
.:::..: ::.:::: . :.. .: . ::..::.:: . :.:.
CCDS81 MAPSVPAAEPEYPKGIRAVLLGPPGAGKGTQAPRLAENFCVCHLATGDMLRAMVASGSEL
10 20 30 40 50 60
60 70 80 90 100
pF1KE3 GVLAKAFIDQGKLIPDDVMTRLALHELKN-LTQYSWLLDGFPRTLPQAEALD-----RAY
: :: .: :::. :.....: ..:.. : . ..::::::::. ::: :: :
CCDS81 GKKLKATMDAGKLVSDEMVVELIEKNLETPLCKNGFLLDGFPRTVRQAEMLDDLMEKRKE
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE3 QIDTVINLNVPFEVIKQRLTARWIHPASGRVYNIEFNPPKTVGIDDLTGEPLIQREDDKP
..:.::....: .. .:.:.: ::: ::: :. :::::: ::.::::::.: ::.
CCDS81 KLDSVIEFSIPDSLLIRRITGRLIHPKSGRSYHEEFNPPKEPMKDDITGEPLIRRSDDNE
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE3 ETVIKRLKAYEDQTKPVLEYYQKKGVLETFSGTETNKIWPYVYAFLQTKVPQRSQKASVT
... ::.::. :: :..:::.:.:. ......: .
CCDS81 KALKIRLQAYHTQTTPLIEYYRKRGIHSAIDASQTPDVVFASILAAFSKATC
190 200 210 220 230
pF1KE3 P
>>CCDS373.1 AK2 gene_id:204|Hs108|chr1 (232 aa)
initn: 613 init1: 299 opt: 580 Z-score: 723.9 bits: 141.2 E(32554): 5.3e-34
Smith-Waterman score: 580; 43.8% identity (74.9% similar) in 203 aa overlap (8-204:16-218)
10 20 30 40 50
pF1KE3 MGASARLLRAVIMGAPGSGKGTVSSRITTHFELKHLSSGDLLRDNMLRGTEI
.:::..: ::.:::: . :.. .: . ::..::.:: . :.:.
CCDS37 MAPSVPAAEPEYPKGIRAVLLGPPGAGKGTQAPRLAENFCVCHLATGDMLRAMVASGSEL
10 20 30 40 50 60
60 70 80 90 100
pF1KE3 GVLAKAFIDQGKLIPDDVMTRLALHELKN-LTQYSWLLDGFPRTLPQAEALD-----RAY
: :: .: :::. :.....: ..:.. : . ..::::::::. ::: :: :
CCDS37 GKKLKATMDAGKLVSDEMVVELIEKNLETPLCKNGFLLDGFPRTVRQAEMLDDLMEKRKE
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE3 QIDTVINLNVPFEVIKQRLTARWIHPASGRVYNIEFNPPKTVGIDDLTGEPLIQREDDKP
..:.::....: .. .:.:.: ::: ::: :. :::::: ::.::::::.: ::.
CCDS37 KLDSVIEFSIPDSLLIRRITGRLIHPKSGRSYHEEFNPPKEPMKDDITGEPLIRRSDDNE
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE3 ETVIKRLKAYEDQTKPVLEYYQKKGVLETFSGTETNKIWPYVYAFLQTKVPQRSQKASVT
... ::.::. :: :..:::.:.:. ......: .
CCDS37 KALKIRLQAYHTQTTPLIEYYRKRGIHSAIDASQTPDVVFASILAAFSKATS
190 200 210 220 230
pF1KE3 P
>>CCDS374.1 AK2 gene_id:204|Hs108|chr1 (239 aa)
initn: 613 init1: 299 opt: 580 Z-score: 723.7 bits: 141.2 E(32554): 5.5e-34
Smith-Waterman score: 580; 43.8% identity (74.9% similar) in 203 aa overlap (8-204:16-218)
10 20 30 40 50
pF1KE3 MGASARLLRAVIMGAPGSGKGTVSSRITTHFELKHLSSGDLLRDNMLRGTEI
.:::..: ::.:::: . :.. .: . ::..::.:: . :.:.
CCDS37 MAPSVPAAEPEYPKGIRAVLLGPPGAGKGTQAPRLAENFCVCHLATGDMLRAMVASGSEL
10 20 30 40 50 60
60 70 80 90 100
pF1KE3 GVLAKAFIDQGKLIPDDVMTRLALHELKN-LTQYSWLLDGFPRTLPQAEALD-----RAY
: :: .: :::. :.....: ..:.. : . ..::::::::. ::: :: :
CCDS37 GKKLKATMDAGKLVSDEMVVELIEKNLETPLCKNGFLLDGFPRTVRQAEMLDDLMEKRKE
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE3 QIDTVINLNVPFEVIKQRLTARWIHPASGRVYNIEFNPPKTVGIDDLTGEPLIQREDDKP
..:.::....: .. .:.:.: ::: ::: :. :::::: ::.::::::.: ::.
CCDS37 KLDSVIEFSIPDSLLIRRITGRLIHPKSGRSYHEEFNPPKEPMKDDITGEPLIRRSDDNE
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE3 ETVIKRLKAYEDQTKPVLEYYQKKGVLETFSGTETNKIWPYVYAFLQTKVPQRSQKASVT
... ::.::. :: :..:::.:.:. ......: .
CCDS37 KALKIRLQAYHTQTTPLIEYYRKRGIHSAIDASQTPDVVFASILAAFSKATCKDLVMFI
190 200 210 220 230
pF1KE3 P
>>CCDS81294.1 AK2 gene_id:204|Hs108|chr1 (190 aa)
initn: 464 init1: 299 opt: 406 Z-score: 510.1 bits: 101.4 E(32554): 4.3e-22
Smith-Waterman score: 406; 39.9% identity (71.8% similar) in 163 aa overlap (48-204:14-176)
20 30 40 50 60 70
pF1KE3 SGKGTVSSRITTHFELKHLSSGDLLRDNMLRGTEIGVLAKAFIDQGKLIPDDVMTRLALH
.: . .:. .: . :.....: .
CCDS81 MAPSVPAAEPEYPKGIRAVLLGPPGAGKGTQVSDEMVVELIEK
10 20 30 40
80 90 100 110 120 130
pF1KE3 ELKN-LTQYSWLLDGFPRTLPQAEALD-----RAYQIDTVINLNVPFEVIKQRLTARWIH
.:.. : . ..::::::::. ::: :: : ..:.::....: .. .:.:.: ::
CCDS81 NLETPLCKNGFLLDGFPRTVRQAEMLDDLMEKRKEKLDSVIEFSIPDSLLIRRITGRLIH
50 60 70 80 90 100
140 150 160 170 180 190
pF1KE3 PASGRVYNIEFNPPKTVGIDDLTGEPLIQREDDKPETVIKRLKAYEDQTKPVLEYYQKKG
: ::: :. :::::: ::.::::::.: ::. ... ::.::. :: :..:::.:.:
CCDS81 PKSGRSYHEEFNPPKEPMKDDITGEPLIRRSDDNEKALKIRLQAYHTQTTPLIEYYRKRG
110 120 130 140 150 160
200 210 220
pF1KE3 VLETFSGTETNKIWPYVYAFLQTKVPQRSQKASVTP
. ......: .
CCDS81 IHSAIDASQTPDVVFASILAAFSKATS
170 180 190
>>CCDS6954.1 AK8 gene_id:158067|Hs108|chr9 (479 aa)
initn: 272 init1: 120 opt: 307 Z-score: 381.3 bits: 78.9 E(32554): 6.4e-15
Smith-Waterman score: 307; 27.4% identity (60.9% similar) in 215 aa overlap (9-219:270-477)
10 20 30
pF1KE3 MGASARLLRAVIMGAPGSGKGTVSSRITTHFELKHLSS
:....: ::::. .. .. ...: ..
CCDS69 ISADQPCVDVFYQALTYVQSNHRTNAPFTPRVLLLGPVGSGKSLQAALLAQKYRLVNVCC
240 250 260 270 280 290
40 50 60 70 80 90
pF1KE3 GDLLRDNMLRGTEIGVLAKAFIDQGKLIPDDVMTRLALHEL--KNLTQYSWLLDGFPRTL
:.::.. . : .: : . :... .::... .. ..: .. : .:.: : :: :
CCDS69 GQLLKEAVADRTTFGELIQPFFEKEMAVPDSLLMKVLSQRLDQQDCIQKGWVLHGVPRDL
300 310 320 330 340 350
100 110 120 130 140 150
pF1KE3 PQAEALDR-AYQIDTVINLNVPFEVIKQRLTARWIHPASGRVYNIEFNPPKTVGIDDLTG
::. :.: .:. . :. :::::. : .::: : : :..:. :.. ..:: :. :.
CCDS69 DQAHLLNRLGYNPNRVFFLNVPFDSIMERLTLRRIDPVTGERYHLMYKPPPTMEIQ----
360 370 380 390 400 410
160 170 180 190 200 210
pF1KE3 EPLIQREDDKPETVIKRLKAYEDQTKPVLEYYQKKGVLETFSGTETN-KIWPYVYAFLQT
:.: : : : .. . .. . . : : :..: . .. :. . . .
CCDS69 ARLLQNPKDAEEQVKLKMDLFYRNSADLEQLY---GSAITLNGDQDPYTVFEYIESGIIN
420 430 440 450 460 470
220
pF1KE3 KVPQRSQKASVTP
.:..
CCDS69 PLPKKIP
227 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 01:29:40 2016 done: Mon Nov 7 01:29:40 2016
Total Scan time: 2.160 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]