Result of FASTA (ccds) for
pFN21AE3588
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3588, 786 aa
1>>>pF1KE3588 786 - 786 aa - 786 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.8858+/-0.000881; mu= 13.4579+/- 0.053
mean_var=123.7085+/-24.194, 0's: 0 Z-trim(110.1): 21 B-trim: 0 in 0/54
Lambda= 0.115312
statistics sampled from 11373 (11391) to 11373 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.713), E-opt: 0.2 (0.35), width: 16
Scan time: 3.240
The best scores are: opt bits E(32554)
CCDS10467.1 CCNF gene_id:899|Hs108|chr16 ( 786) 5305 894.2 0
CCDS45031.1 CCNA1 gene_id:8900|Hs108|chr13 ( 421) 399 77.9 3.8e-14
CCDS45030.1 CCNA1 gene_id:8900|Hs108|chr13 ( 464) 399 77.9 4.1e-14
CCDS9357.1 CCNA1 gene_id:8900|Hs108|chr13 ( 465) 399 77.9 4.1e-14
CCDS3723.1 CCNA2 gene_id:890|Hs108|chr4 ( 432) 377 74.2 4.9e-13
>>CCDS10467.1 CCNF gene_id:899|Hs108|chr16 (786 aa)
initn: 5305 init1: 5305 opt: 5305 Z-score: 4774.5 bits: 894.2 E(32554): 0
Smith-Waterman score: 5305; 100.0% identity (100.0% similar) in 786 aa overlap (1-786:1-786)
10 20 30 40 50 60
pF1KE3 MGSGGVVHCRCAKCFCYPTKRRIRRRPRNLTILSLPEDVLFHILKWLSVEDILAVRAVHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 MGSGGVVHCRCAKCFCYPTKRRIRRRPRNLTILSLPEDVLFHILKWLSVEDILAVRAVHS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 QLKDLVDNHASVWACASFQELWPSPGNLKLFERAAEKGNFEAAVKLGIAYLYNEGLSVSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 QLKDLVDNHASVWACASFQELWPSPGNLKLFERAAEKGNFEAAVKLGIAYLYNEGLSVSD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 EARAEVNGLKASRFFSLAERLNVGAAPFIWLFIRPPWSVSGSCCKAVVHESLRAECQLQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 EARAEVNGLKASRFFSLAERLNVGAAPFIWLFIRPPWSVSGSCCKAVVHESLRAECQLQR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 THKASILHCLGRVLSLFEDEEKQQQAHDLFEEAAHQGCLTSSYLLWESDRRTDVSDPGRC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 THKASILHCLGRVLSLFEDEEKQQQAHDLFEEAAHQGCLTSSYLLWESDRRTDVSDPGRC
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 LHSFRKLRDYAAKGCWEAQLSLAKACANANQLGLEVRASSEIVCQLFQASQAVSKQQVFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 LHSFRKLRDYAAKGCWEAQLSLAKACANANQLGLEVRASSEIVCQLFQASQAVSKQQVFS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 VQKGLNDTMRYILIDWLVEVATMKDFTSLCLHLTVECVDRYLRRRLVPRYRLQLLGIACM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 VQKGLNDTMRYILIDWLVEVATMKDFTSLCLHLTVECVDRYLRRRLVPRYRLQLLGIACM
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 VICTRFISKEILTIREAVWLTDNTYKYEDLVRMMGEIVSALEGKIRVPTVVDYKEVLLTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 VICTRFISKEILTIREAVWLTDNTYKYEDLVRMMGEIVSALEGKIRVPTVVDYKEVLLTL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 VPVELRTQHLCSFLCELSLLHTSLSAYAPARLAAAALLLARLTHGQTQPWTTQLWDLTGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 VPVELRTQHLCSFLCELSLLHTSLSAYAPARLAAAALLLARLTHGQTQPWTTQLWDLTGF
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 SYEDLIPCVLSLHKKCFHDDAPKDYRQVSLTAVKQRFEDKRYGEISQEEVLSYSQLCAAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 SYEDLIPCVLSLHKKCFHDDAPKDYRQVSLTAVKQRFEDKRYGEISQEEVLSYSQLCAAL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 GVTQDSPDPPTFLSTGEIHAFLSSPSGRRTKRKRENSLQEDRGSFVTTPTAELSSQEETL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 GVTQDSPDPPTFLSTGEIHAFLSSPSGRRTKRKRENSLQEDRGSFVTTPTAELSSQEETL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 LGSFLDWSLDCCSGYEGDQESEGEKEGDVTAPSGILDVTVVYLNPEQHCCQESSDEEACP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 LGSFLDWSLDCCSGYEGDQESEGEKEGDVTAPSGILDVTVVYLNPEQHCCQESSDEEACP
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 EDKGPQDPQALALDTQIPATPGPKPLVRTSREPGKDVTTSGYSSVSTASPTSSVDGGLGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 EDKGPQDPQALALDTQIPATPGPKPLVRTSREPGKDVTTSGYSSVSTASPTSSVDGGLGA
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 LPQPTSVLSLDSDSHTQPCHHQARKSCLQCRPPSPPESSVPQQQVKRINLCIHSEEEDMN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 LPQPTSVLSLDSDSHTQPCHHQARKSCLQCRPPSPPESSVPQQQVKRINLCIHSEEEDMN
730 740 750 760 770 780
pF1KE3 LGLVRL
::::::
CCDS10 LGLVRL
>>CCDS45031.1 CCNA1 gene_id:8900|Hs108|chr13 (421 aa)
initn: 306 init1: 306 opt: 399 Z-score: 367.4 bits: 77.9 E(32554): 3.8e-14
Smith-Waterman score: 399; 28.1% identity (58.8% similar) in 342 aa overlap (200-529:84-413)
170 180 190 200 210 220
pF1KE3 ESLRAECQLQRTHKASILHCLGRVLSLFEDEEKQQQAHDLFEEAAHQG----CLTSSYLL
.: .:. :.. . .:: : . .
CCDS45 GQGITRIRCYSGSENAFPPAGKKALPDCGVQEPPKQGFDIYMDELEQGDRDSCSVREGMA
60 70 80 90 100 110
230 240 250 260 270 280
pF1KE3 WESDRRTDVSDPGRCLHSFRKLRDYAAKGCWEAQLSLAKACANANQLGLEVRASSEIVCQ
.:. ..:.. :: : : :. . . .. :: . . ..:: .: .: . .
CCDS45 FEDVYEVDTGTLKSDLH-F--LLDFNTVSPMLVDSSLLSQSEDISSLGTDVINVTEYAEE
120 130 140 150 160 170
290 300 310 320 330 340
pF1KE3 LFQASQAVS-----KQQVFSVQKGLNDTMRYILIDWLVEVATMKDFTSLCLHLTVECVDR
..: . . : . .. : ... :: ::.::::::. . . :.:.:. .::
CCDS45 IYQYLREAEIRHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAVNFLDR
180 190 200 210 220 230
350 360 370 380 390
pF1KE3 YLRRRLVPRYRLQLLGIACMVICTRFISKEILT--IREAVWLTDNTYKYEDLVRMMGEIV
.: : : .:::.: : :.. ... .:: . : :..::.:: ..:..: ..
CCDS45 FLSCMSVLRGKLQLVGTAAMLLASKY--EEIYPPEVDEFVYITDDTYTKRQLLKMEHLLL
240 250 260 270 280
400 410 420 430 440 450
pF1KE3 SALEGKIRVPTVVDYKEVLLTLVPVELRTQHLCSFLCELSLLHTS-LSAYAPARLAAAAL
..: . :::. .. : : .::..: ... :::::... . : :. .::::.
CCDS45 KVLAFDLTVPTTNQFLLQYLRRQGVCVRTENLAKYVAELSLLEADPFLKYLPSLIAAAAF
290 300 310 320 330 340
460 470 480 490 500 510
pF1KE3 LLARLTHGQTQPWTTQLWDLTGFSYEDLIPCVLSLHKKCFHDDAPKDYRQVSLTAVKQRF
:: : .. . : : .::.: ...::. ::: . : :. .: :.....
CCDS45 CLANYTVNK-HFWPETLAAFTGYSLSEIVPCLSELHKAYL--DIPHRPQQ----AIREKY
350 360 370 380 390 400
520 530 540 550 560 570
pF1KE3 EDKRYGEISQEEVLSYSQLCAALGVTQDSPDPPTFLSTGEIHAFLSSPSGRRTKRKRENS
. ..: .: :
CCDS45 KASKYLCVSLMEPPAVLLLQ
410 420
>>CCDS45030.1 CCNA1 gene_id:8900|Hs108|chr13 (464 aa)
initn: 306 init1: 306 opt: 399 Z-score: 366.8 bits: 77.9 E(32554): 4.1e-14
Smith-Waterman score: 399; 28.1% identity (58.8% similar) in 342 aa overlap (200-529:127-456)
170 180 190 200 210 220
pF1KE3 ESLRAECQLQRTHKASILHCLGRVLSLFEDEEKQQQAHDLFEEAAHQG----CLTSSYLL
.: .:. :.. . .:: : . .
CCDS45 GQGITRIRCYSGSENAFPPAGKKALPDCGVQEPPKQGFDIYMDELEQGDRDSCSVREGMA
100 110 120 130 140 150
230 240 250 260 270 280
pF1KE3 WESDRRTDVSDPGRCLHSFRKLRDYAAKGCWEAQLSLAKACANANQLGLEVRASSEIVCQ
.:. ..:.. :: : : :. . . .. :: . . ..:: .: .: . .
CCDS45 FEDVYEVDTGTLKSDLH-F--LLDFNTVSPMLVDSSLLSQSEDISSLGTDVINVTEYAEE
160 170 180 190 200 210
290 300 310 320 330 340
pF1KE3 LFQASQAVS-----KQQVFSVQKGLNDTMRYILIDWLVEVATMKDFTSLCLHLTVECVDR
..: . . : . .. : ... :: ::.::::::. . . :.:.:. .::
CCDS45 IYQYLREAEIRHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAVNFLDR
220 230 240 250 260 270
350 360 370 380 390
pF1KE3 YLRRRLVPRYRLQLLGIACMVICTRFISKEILT--IREAVWLTDNTYKYEDLVRMMGEIV
.: : : .:::.: : :.. ... .:: . : :..::.:: ..:..: ..
CCDS45 FLSCMSVLRGKLQLVGTAAMLLASKY--EEIYPPEVDEFVYITDDTYTKRQLLKMEHLLL
280 290 300 310 320 330
400 410 420 430 440 450
pF1KE3 SALEGKIRVPTVVDYKEVLLTLVPVELRTQHLCSFLCELSLLHTS-LSAYAPARLAAAAL
..: . :::. .. : : .::..: ... :::::... . : :. .::::.
CCDS45 KVLAFDLTVPTTNQFLLQYLRRQGVCVRTENLAKYVAELSLLEADPFLKYLPSLIAAAAF
340 350 360 370 380 390
460 470 480 490 500 510
pF1KE3 LLARLTHGQTQPWTTQLWDLTGFSYEDLIPCVLSLHKKCFHDDAPKDYRQVSLTAVKQRF
:: : .. . : : .::.: ...::. ::: . : :. .: :.....
CCDS45 CLANYTVNK-HFWPETLAAFTGYSLSEIVPCLSELHKAYL--DIPHRPQQ----AIREKY
400 410 420 430 440
520 530 540 550 560 570
pF1KE3 EDKRYGEISQEEVLSYSQLCAALGVTQDSPDPPTFLSTGEIHAFLSSPSGRRTKRKRENS
. ..: .: :
CCDS45 KASKYLCVSLMEPPAVLLLQ
450 460
>>CCDS9357.1 CCNA1 gene_id:8900|Hs108|chr13 (465 aa)
initn: 306 init1: 306 opt: 399 Z-score: 366.8 bits: 77.9 E(32554): 4.1e-14
Smith-Waterman score: 399; 28.1% identity (58.8% similar) in 342 aa overlap (200-529:128-457)
170 180 190 200 210 220
pF1KE3 ESLRAECQLQRTHKASILHCLGRVLSLFEDEEKQQQAHDLFEEAAHQG----CLTSSYLL
.: .:. :.. . .:: : . .
CCDS93 GQGITRIRCYSGSENAFPPAGKKALPDCGVQEPPKQGFDIYMDELEQGDRDSCSVREGMA
100 110 120 130 140 150
230 240 250 260 270 280
pF1KE3 WESDRRTDVSDPGRCLHSFRKLRDYAAKGCWEAQLSLAKACANANQLGLEVRASSEIVCQ
.:. ..:.. :: : : :. . . .. :: . . ..:: .: .: . .
CCDS93 FEDVYEVDTGTLKSDLH-F--LLDFNTVSPMLVDSSLLSQSEDISSLGTDVINVTEYAEE
160 170 180 190 200 210
290 300 310 320 330 340
pF1KE3 LFQASQAVS-----KQQVFSVQKGLNDTMRYILIDWLVEVATMKDFTSLCLHLTVECVDR
..: . . : . .. : ... :: ::.::::::. . . :.:.:. .::
CCDS93 IYQYLREAEIRHRPKAHYMKKQPDITEGMRTILVDWLVEVGEEYKLRAETLYLAVNFLDR
220 230 240 250 260 270
350 360 370 380 390
pF1KE3 YLRRRLVPRYRLQLLGIACMVICTRFISKEILT--IREAVWLTDNTYKYEDLVRMMGEIV
.: : : .:::.: : :.. ... .:: . : :..::.:: ..:..: ..
CCDS93 FLSCMSVLRGKLQLVGTAAMLLASKY--EEIYPPEVDEFVYITDDTYTKRQLLKMEHLLL
280 290 300 310 320 330
400 410 420 430 440 450
pF1KE3 SALEGKIRVPTVVDYKEVLLTLVPVELRTQHLCSFLCELSLLHTS-LSAYAPARLAAAAL
..: . :::. .. : : .::..: ... :::::... . : :. .::::.
CCDS93 KVLAFDLTVPTTNQFLLQYLRRQGVCVRTENLAKYVAELSLLEADPFLKYLPSLIAAAAF
340 350 360 370 380 390
460 470 480 490 500 510
pF1KE3 LLARLTHGQTQPWTTQLWDLTGFSYEDLIPCVLSLHKKCFHDDAPKDYRQVSLTAVKQRF
:: : .. . : : .::.: ...::. ::: . : :. .: :.....
CCDS93 CLANYTVNK-HFWPETLAAFTGYSLSEIVPCLSELHKAYL--DIPHRPQQ----AIREKY
400 410 420 430 440
520 530 540 550 560 570
pF1KE3 EDKRYGEISQEEVLSYSQLCAALGVTQDSPDPPTFLSTGEIHAFLSSPSGRRTKRKRENS
. ..: .: :
CCDS93 KASKYLCVSLMEPPAVLLLQ
450 460
>>CCDS3723.1 CCNA2 gene_id:890|Hs108|chr4 (432 aa)
initn: 301 init1: 219 opt: 377 Z-score: 347.5 bits: 74.2 E(32554): 4.9e-13
Smith-Waterman score: 377; 32.6% identity (64.3% similar) in 230 aa overlap (302-526:203-422)
280 290 300 310 320 330
pF1KE3 LGLEVRASSEIVCQLFQASQAVSKQQVFSVQKGLNDTMRYILIDWLVEVATMKDFTSLCL
: ....:: ::.::::::. . . :
CCDS37 NEVPDYHEDIHTYLREMEVKCKPKVGYMKKQPDITNSMRAILVDWLVEVGEEYKLQNETL
180 190 200 210 220 230
340 350 360 370 380
pF1KE3 HLTVECVDRYLRRRLVPRYRLQLLGIACMVICTRFISKEILT--IREAVWLTDNTYKYED
::.:. .::.: : : .:::.: : :.. ..: .:: . : :..::.:: ..
CCDS37 HLAVNYIDRFLSSMSVLRGKLQLVGTAAMLLASKF--EEIYPPEVAEFVYITDDTYTKKQ
240 250 260 270 280 290
390 400 410 420 430 440
pF1KE3 LVRMMGEIVSALEGKIRVPTVVDY-KEVLLTLVPVELRTQHLCSFLCELSLLHTS-LSAY
..:: ....: . .::: .. . .: :.. ... : :: ::::. .. :
CCDS37 VLRMEHLVLKVLTFDLAAPTVNQFLTQYFLHQQPANCKVESLAMFLGELSLIDADPYLKY
300 310 320 330 340 350
450 460 470 480 490 500
pF1KE3 APARLAAAALLLARLT-HGQTQPWTTQLWDLTGFSYEDLIPCVLSLHKKCFHDDAPKDYR
:. .:.::. :: : ::. : .: ::.. :.: ::...::. .. ::. .
CCDS37 LPSVIAGAAFHLALYTVTGQS--WPESLIRKTGYTLESLKPCLMDLHQTYLK--APQHAQ
360 370 380 390 400
510 520 530 540 550 560
pF1KE3 QVSLTAVKQRFEDKRYGEISQEEVLSYSQLCAALGVTQDSPDPPTFLSTGEIHAFLSSPS
: ..........: .:
CCDS37 Q----SIREKYKNSKYHGVSLLNPPETLNL
410 420 430
786 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 01:42:12 2016 done: Mon Nov 7 01:42:12 2016
Total Scan time: 3.240 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]