Result of FASTA (omim) for
pFN21AE3580
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3580, 999 aa
1>>>pF1KE3580 999 - 999 aa - 999 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.7290+/-0.000481; mu= 16.3804+/- 0.030
mean_var=259.7159+/-53.696, 0's: 0 Z-trim(117.2): 501 B-trim: 553 in 2/57
Lambda= 0.079584
statistics sampled from 28318 (29059) to 28318 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.679), E-opt: 0.2 (0.341), width: 16
Scan time: 15.310
The best scores are: opt bits E(85289)
NP_001164158 (OMIM: 611141) E3 ubiquitin-protein l (1056) 6832 799.6 0
NP_543151 (OMIM: 611141) E3 ubiquitin-protein liga (1070) 6604 773.4 0
NP_001164157 (OMIM: 611141) E3 ubiquitin-protein l (1066) 6558 768.1 0
XP_011539039 (OMIM: 611141) PREDICTED: E3 ubiquiti (1219) 5942 697.5 1.1e-199
XP_016855850 (OMIM: 611141) PREDICTED: E3 ubiquiti (1094) 5879 690.2 1.6e-197
NP_001164159 (OMIM: 611141) E3 ubiquitin-protein l (1005) 4786 564.6 9.3e-160
XP_016855842 (OMIM: 611141) PREDICTED: E3 ubiquiti (1276) 4443 525.4 7.6e-148
XP_016855855 (OMIM: 611141) PREDICTED: E3 ubiquiti ( 911) 4293 507.9 9.7e-143
XP_006710435 (OMIM: 611141) PREDICTED: E3 ubiquiti (1034) 4195 496.8 2.5e-139
XP_011539044 (OMIM: 611141) PREDICTED: E3 ubiquiti (1183) 4195 496.9 2.7e-139
XP_011539038 (OMIM: 611141) PREDICTED: E3 ubiquiti (1240) 4191 496.4 3.8e-139
XP_016855853 (OMIM: 611141) PREDICTED: E3 ubiquiti (1029) 4061 481.4 1.1e-134
XP_011539043 (OMIM: 611141) PREDICTED: E3 ubiquiti (1184) 3952 469.0 6.8e-131
NP_001164160 (OMIM: 611141) E3 ubiquitin-protein l ( 753) 3659 435.0 7.1e-121
XP_016855843 (OMIM: 611141) PREDICTED: E3 ubiquiti (1264) 3466 413.2 4.4e-114
XP_016855845 (OMIM: 611141) PREDICTED: E3 ubiquiti (1240) 2696 324.8 1.8e-87
XP_016855854 (OMIM: 611141) PREDICTED: E3 ubiquiti ( 932) 2692 324.1 2.1e-87
XP_016855852 (OMIM: 611141) PREDICTED: E3 ubiquiti (1033) 2692 324.2 2.2e-87
XP_016855851 (OMIM: 611141) PREDICTED: E3 ubiquiti (1047) 2692 324.2 2.3e-87
XP_016855849 (OMIM: 611141) PREDICTED: E3 ubiquiti (1134) 2692 324.3 2.4e-87
XP_016855848 (OMIM: 611141) PREDICTED: E3 ubiquiti (1144) 2692 324.3 2.4e-87
XP_016855847 (OMIM: 611141) PREDICTED: E3 ubiquiti (1148) 2692 324.3 2.4e-87
XP_016855846 (OMIM: 611141) PREDICTED: E3 ubiquiti (1232) 2692 324.3 2.5e-87
XP_011539033 (OMIM: 611141) PREDICTED: E3 ubiquiti (1273) 2692 324.3 2.5e-87
XP_016855841 (OMIM: 611141) PREDICTED: E3 ubiquiti (1283) 2692 324.3 2.5e-87
XP_016855840 (OMIM: 611141) PREDICTED: E3 ubiquiti (1291) 2692 324.4 2.5e-87
XP_016855839 (OMIM: 611141) PREDICTED: E3 ubiquiti (1293) 2692 324.4 2.5e-87
XP_016855838 (OMIM: 611141) PREDICTED: E3 ubiquiti (1297) 2692 324.4 2.5e-87
XP_016855844 (OMIM: 611141) PREDICTED: E3 ubiquiti (1241) 2453 296.9 4.5e-79
NP_065825 (OMIM: 608677,615092) E3 ubiquitin-prote (1006) 1674 207.3 3.4e-52
XP_016881362 (OMIM: 608677,615092) PREDICTED: E3 u ( 834) 1179 150.3 3.9e-35
XP_016881363 (OMIM: 608677,615092) PREDICTED: E3 u ( 511) 954 124.2 1.8e-27
XP_016881364 (OMIM: 608677,615092) PREDICTED: E3 u ( 503) 949 123.6 2.7e-27
XP_011524400 (OMIM: 608677,615092) PREDICTED: E3 u ( 516) 759 101.8 1e-20
XP_016863591 (OMIM: 106410,600919) PREDICTED: anky (1838) 521 75.3 3.3e-12
XP_016863600 (OMIM: 106410,600919) PREDICTED: anky (1755) 444 66.5 1.5e-09
XP_016863598 (OMIM: 106410,600919) PREDICTED: anky (1770) 444 66.5 1.5e-09
XP_016863594 (OMIM: 106410,600919) PREDICTED: anky (1810) 444 66.5 1.5e-09
XP_016863584 (OMIM: 106410,600919) PREDICTED: anky (1871) 444 66.5 1.5e-09
XP_016863569 (OMIM: 106410,600919) PREDICTED: anky (1970) 444 66.5 1.6e-09
XP_016863568 (OMIM: 106410,600919) PREDICTED: anky (2006) 444 66.5 1.6e-09
XP_016863566 (OMIM: 106410,600919) PREDICTED: anky (4074) 444 67.0 2.3e-09
XP_016863561 (OMIM: 106410,600919) PREDICTED: anky (4137) 444 67.0 2.3e-09
XP_016863558 (OMIM: 106410,600919) PREDICTED: anky (4175) 444 67.0 2.4e-09
XP_016861517 (OMIM: 611122) PREDICTED: serine/thre ( 687) 425 63.6 4.1e-09
XP_005251814 (OMIM: 600831) PREDICTED: death-assoc ( 839) 425 63.8 4.5e-09
XP_011531848 (OMIM: 611122) PREDICTED: serine/thre ( 997) 425 63.9 5e-09
XP_011531847 (OMIM: 611122) PREDICTED: serine/thre ( 997) 425 63.9 5e-09
XP_011531849 (OMIM: 611122) PREDICTED: serine/thre ( 997) 425 63.9 5e-09
XP_011531844 (OMIM: 611122) PREDICTED: serine/thre (1025) 425 63.9 5e-09
>>NP_001164158 (OMIM: 611141) E3 ubiquitin-protein ligas (1056 aa)
initn: 6832 init1: 6832 opt: 6832 Z-score: 4258.5 bits: 799.6 E(85289): 0
Smith-Waterman score: 6832; 99.7% identity (99.9% similar) in 999 aa overlap (1-999:58-1056)
10 20 30
pF1KE3 MGWKPSEARGQSQSFQASGLQPRSLKAARR
::::::::::::::::::::::::::::::
NP_001 CPVAQEGLGARSRPRVAPRSLARCGPSSRLMGWKPSEARGQSQSFQASGLQPRSLKAARR
30 40 50 60 70 80
40 50 60 70 80 90
pF1KE3 ATGRPDRSRAAPPNMDPDPQAGVQVGMRVVRGVDWKWGQQDGGEGGVGTVVELGRHGSPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ATGRPDRSRAAPPNMDPDPQAGVQVGMRVVRGVDWKWGQQDGGEGGVGTVVELGRHGSPS
90 100 110 120 130 140
100 110 120 130 140 150
pF1KE3 TPDRTVVVQWDQGTRTNYRAGYQGAHDLLLYDNAQIGVRHPNIICDCCKKHGLRGMRWKC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TPDRTVVVQWDQGTRTNYRAGYQGAHDLLLYDNAQIGVRHPNIICDCCKKHGLRGMRWKC
150 160 170 180 190 200
160 170 180 190 200 210
pF1KE3 RVCLDYDLCTQCYMHNKHELAHAFDRYETAHSRPVTLSPRQGLPRIPLRGIFQGAKVVRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RVCLDYDLCTQCYMHNKHELAHAFDRYETAHSRPVTLSPRQGLPRIPLRGIFQGAKVVRG
210 220 230 240 250 260
220 230 240 250 260 270
pF1KE3 PDWEWGSQDGGEGKPGRVVDIRGWDVETGRSVASVTWADGTTNVYRVGYKGKVDLKCVGE
::::::::::::::::::::::::::::::::::::::::::::::::.:::::::::::
NP_001 PDWEWGSQDGGEGKPGRVVDIRGWDVETGRSVASVTWADGTTNVYRVGHKGKVDLKCVGE
270 280 290 300 310 320
280 290 300 310 320 330
pF1KE3 AAGGFYYKDHLPRLGKPAELQRRVSADSQPFQHGDKVKCLLDTDVLREMQEGHGGWNPRM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AAGGFYYKDHLPRLGKPAELQRRVSADSQPFQHGDKVKCLLDTDVLREMQEGHGGWNPRM
330 340 350 360 370 380
340 350 360 370 380 390
pF1KE3 AEFIGQTGTVHRITDRGDVRVQFNHETRWTFHPGALTKHHSFWVGDVVRVIGDLDTVKRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AEFIGQTGTVHRITDRGDVRVQFNHETRWTFHPGALTKHHSFWVGDVVRVIGDLDTVKRL
390 400 410 420 430 440
400 410 420 430 440 450
pF1KE3 QAGHGEWTDDMAPALGRVGKVVKVFGDGNLRVAVAGQRWTFSPSCLVAYRPEEDANLDVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QAGHGEWTDDMAPALGRVGKVVKVFGDGNLRVAVAGQRWTFSPSCLVAYRPEEDANLDVA
450 460 470 480 490 500
460 470 480 490 500 510
pF1KE3 ERARENKSSLSVALDKLRAQKSDPEHPGRLVVEVALGNAARALGLLRRRPEQVDTKNQGR
::::::::::::::::::::::::::::::::::::::::::: ::::::::::::::::
NP_001 ERARENKSSLSVALDKLRAQKSDPEHPGRLVVEVALGNAARALDLLRRRPEQVDTKNQGR
510 520 530 540 550 560
520 530 540 550 560 570
pF1KE3 TALQVAAYLGQVELIRLLLQARAGVDLPDDEGNTALHYAALGNQPEATRVLLSAGCRADA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TALQVAAYLGQVELIRLLLQARAGVDLPDDEGNTALHYAALGNQPEATRVLLSAGCRADA
570 580 590 600 610 620
580 590 600 610 620 630
pF1KE3 INSTQSTALHVAVQRGFLEVVRALCERGCDVNLPDAHSDTPLHSAISAGTGAGGIVEVLT
::::::::::::::::::::::::::::::::::::::::::::::::::::.:::::::
NP_001 INSTQSTALHVAVQRGFLEVVRALCERGCDVNLPDAHSDTPLHSAISAGTGASGIVEVLT
630 640 650 660 670 680
640 650 660 670 680 690
pF1KE3 EVPNIDVTATNSQGFTLLHHASLKGHALAVRKILARARQLVDAKKEDGFTALHLAALNNH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EVPNIDVTATNSQGFTLLHHASLKGHALAVRKILARARQLVDAKKEDGFTALHLAALNNH
690 700 710 720 730 740
700 710 720 730 740 750
pF1KE3 REVAQILIREGRCDVNVRNRKLQSPLHLAVQQAHVGLVPLLVDAGCSVNAEDEEGDTALH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 REVAQILIREGRCDVNVRNRKLQSPLHLAVQQAHVGLVPLLVDAGCSVNAEDEEGDTALH
750 760 770 780 790 800
760 770 780 790 800 810
pF1KE3 VALQRHQLLPLVADGAGGDPGPLQLLSRLQASGLPGSAELTVGAAVACFLALEGADVSYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VALQRHQLLPLVADGAGGDPGPLQLLSRLQASGLPGSAELTVGAAVACFLALEGADVSYT
810 820 830 840 850 860
820 830 840 850 860 870
pF1KE3 NHRGRSPLDLAAEGRVLKALQGCAQRFRERQAGGGAAPGPRQTLGTPNTVTNLHVGAAPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NHRGRSPLDLAAEGRVLKALQGCAQRFRERQAGGGAAPGPRQTLGTPNTVTNLHVGAAPG
870 880 890 900 910 920
880 890 900 910 920 930
pF1KE3 PEAAECLVCSELALLVLFSPCQHRTVCEECARRMKKCIRCQVVVSKKLRPDGSEVASAAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PEAAECLVCSELALLVLFSPCQHRTVCEECARRMKKCIRCQVVVSKKLRPDGSEVASAAP
930 940 950 960 970 980
940 950 960 970 980 990
pF1KE3 APGPPRQLVEELQSRYRQMEERITCPICIDSHIRLVFQCGHGACAPCGSALSACPICRQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 APGPPRQLVEELQSRYRQMEERITCPICIDSHIRLVFQCGHGACAPCGSALSACPICRQP
990 1000 1010 1020 1030 1040
pF1KE3 IRDRIQIFV
:::::::::
NP_001 IRDRIQIFV
1050
>>NP_543151 (OMIM: 611141) E3 ubiquitin-protein ligase M (1070 aa)
initn: 6586 init1: 6586 opt: 6604 Z-score: 4117.0 bits: 773.4 E(85289): 0
Smith-Waterman score: 6794; 98.3% identity (98.5% similar) in 1013 aa overlap (1-999:58-1070)
10 20 30
pF1KE3 MGWKPSEARGQSQSFQASGLQPRSLKAARR
::::::::::::::::::::::::::::::
NP_543 CPVAQEGLGARSRPRVAPRSLARCGPSSRLMGWKPSEARGQSQSFQASGLQPRSLKAARR
30 40 50 60 70 80
40 50 60 70
pF1KE3 ATGRPDRSRAA--------------PPNMDPDPQAGVQVGMRVVRGVDWKWGQQDGGEGG
::::::::::: :::::::::::::::::::::::::::::::::::
NP_543 ATGRPDRSRAARPTMDPSAHRSRAAPPNMDPDPQAGVQVGMRVVRGVDWKWGQQDGGEGG
90 100 110 120 130 140
80 90 100 110 120 130
pF1KE3 VGTVVELGRHGSPSTPDRTVVVQWDQGTRTNYRAGYQGAHDLLLYDNAQIGVRHPNIICD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_543 VGTVVELGRHGSPSTPDRTVVVQWDQGTRTNYRAGYQGAHDLLLYDNAQIGVRHPNIICD
150 160 170 180 190 200
140 150 160 170 180 190
pF1KE3 CCKKHGLRGMRWKCRVCLDYDLCTQCYMHNKHELAHAFDRYETAHSRPVTLSPRQGLPRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_543 CCKKHGLRGMRWKCRVCLDYDLCTQCYMHNKHELAHAFDRYETAHSRPVTLSPRQGLPRI
210 220 230 240 250 260
200 210 220 230 240 250
pF1KE3 PLRGIFQGAKVVRGPDWEWGSQDGGEGKPGRVVDIRGWDVETGRSVASVTWADGTTNVYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_543 PLRGIFQGAKVVRGPDWEWGSQDGGEGKPGRVVDIRGWDVETGRSVASVTWADGTTNVYR
270 280 290 300 310 320
260 270 280 290 300 310
pF1KE3 VGYKGKVDLKCVGEAAGGFYYKDHLPRLGKPAELQRRVSADSQPFQHGDKVKCLLDTDVL
::.:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_543 VGHKGKVDLKCVGEAAGGFYYKDHLPRLGKPAELQRRVSADSQPFQHGDKVKCLLDTDVL
330 340 350 360 370 380
320 330 340 350 360 370
pF1KE3 REMQEGHGGWNPRMAEFIGQTGTVHRITDRGDVRVQFNHETRWTFHPGALTKHHSFWVGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_543 REMQEGHGGWNPRMAEFIGQTGTVHRITDRGDVRVQFNHETRWTFHPGALTKHHSFWVGD
390 400 410 420 430 440
380 390 400 410 420 430
pF1KE3 VVRVIGDLDTVKRLQAGHGEWTDDMAPALGRVGKVVKVFGDGNLRVAVAGQRWTFSPSCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_543 VVRVIGDLDTVKRLQAGHGEWTDDMAPALGRVGKVVKVFGDGNLRVAVAGQRWTFSPSCL
450 460 470 480 490 500
440 450 460 470 480 490
pF1KE3 VAYRPEEDANLDVAERARENKSSLSVALDKLRAQKSDPEHPGRLVVEVALGNAARALGLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::
NP_543 VAYRPEEDANLDVAERARENKSSLSVALDKLRAQKSDPEHPGRLVVEVALGNAARALDLL
510 520 530 540 550 560
500 510 520 530 540 550
pF1KE3 RRRPEQVDTKNQGRTALQVAAYLGQVELIRLLLQARAGVDLPDDEGNTALHYAALGNQPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_543 RRRPEQVDTKNQGRTALQVAAYLGQVELIRLLLQARAGVDLPDDEGNTALHYAALGNQPE
570 580 590 600 610 620
560 570 580 590 600 610
pF1KE3 ATRVLLSAGCRADAINSTQSTALHVAVQRGFLEVVRALCERGCDVNLPDAHSDTPLHSAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_543 ATRVLLSAGCRADAINSTQSTALHVAVQRGFLEVVRALCERGCDVNLPDAHSDTPLHSAI
630 640 650 660 670 680
620 630 640 650 660 670
pF1KE3 SAGTGAGGIVEVLTEVPNIDVTATNSQGFTLLHHASLKGHALAVRKILARARQLVDAKKE
::::::.:::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_543 SAGTGASGIVEVLTEVPNIDVTATNSQGFTLLHHASLKGHALAVRKILARARQLVDAKKE
690 700 710 720 730 740
680 690 700 710 720 730
pF1KE3 DGFTALHLAALNNHREVAQILIREGRCDVNVRNRKLQSPLHLAVQQAHVGLVPLLVDAGC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_543 DGFTALHLAALNNHREVAQILIREGRCDVNVRNRKLQSPLHLAVQQAHVGLVPLLVDAGC
750 760 770 780 790 800
740 750 760 770 780 790
pF1KE3 SVNAEDEEGDTALHVALQRHQLLPLVADGAGGDPGPLQLLSRLQASGLPGSAELTVGAAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_543 SVNAEDEEGDTALHVALQRHQLLPLVADGAGGDPGPLQLLSRLQASGLPGSAELTVGAAV
810 820 830 840 850 860
800 810 820 830 840 850
pF1KE3 ACFLALEGADVSYTNHRGRSPLDLAAEGRVLKALQGCAQRFRERQAGGGAAPGPRQTLGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_543 ACFLALEGADVSYTNHRGRSPLDLAAEGRVLKALQGCAQRFRERQAGGGAAPGPRQTLGT
870 880 890 900 910 920
860 870 880 890 900 910
pF1KE3 PNTVTNLHVGAAPGPEAAECLVCSELALLVLFSPCQHRTVCEECARRMKKCIRCQVVVSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_543 PNTVTNLHVGAAPGPEAAECLVCSELALLVLFSPCQHRTVCEECARRMKKCIRCQVVVSK
930 940 950 960 970 980
920 930 940 950 960 970
pF1KE3 KLRPDGSEVASAAPAPGPPRQLVEELQSRYRQMEERITCPICIDSHIRLVFQCGHGACAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_543 KLRPDGSEVASAAPAPGPPRQLVEELQSRYRQMEERITCPICIDSHIRLVFQCGHGACAP
990 1000 1010 1020 1030 1040
980 990
pF1KE3 CGSALSACPICRQPIRDRIQIFV
:::::::::::::::::::::::
NP_543 CGSALSACPICRQPIRDRIQIFV
1050 1060 1070
>>NP_001164157 (OMIM: 611141) E3 ubiquitin-protein ligas (1066 aa)
initn: 4839 init1: 4420 opt: 6558 Z-score: 4088.4 bits: 768.1 E(85289): 0
Smith-Waterman score: 6748; 97.9% identity (98.1% similar) in 1013 aa overlap (1-999:58-1066)
10 20 30
pF1KE3 MGWKPSEARGQSQSFQASGLQPRSLKAARR
::::::::::::::::::::::::::::::
NP_001 CPVAQEGLGARSRPRVAPRSLARCGPSSRLMGWKPSEARGQSQSFQASGLQPRSLKAARR
30 40 50 60 70 80
40 50 60 70
pF1KE3 ATGRPDRSRAA--------------PPNMDPDPQAGVQVGMRVVRGVDWKWGQQDGGEGG
::::::::::: :::::::::::::::::::::::::::::::::::
NP_001 ATGRPDRSRAARPTMDPSAHRSRAAPPNMDPDPQAGVQVGMRVVRGVDWKWGQQDGGEGG
90 100 110 120 130 140
80 90 100 110 120 130
pF1KE3 VGTVVELGRHGSPSTPDRTVVVQWDQGTRTNYRAGYQGAHDLLLYDNAQIGVRHPNIICD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VGTVVELGRHGSPSTPDRTVVVQWDQGTRTNYRAGYQGAHDLLLYDNAQIGVRHPNIICD
150 160 170 180 190 200
140 150 160 170 180 190
pF1KE3 CCKKHGLRGMRWKCRVCLDYDLCTQCYMHNKHELAHAFDRYETAHSRPVTLSPRQGLPRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CCKKHGLRGMRWKCRVCLDYDLCTQCYMHNKHELAHAFDRYETAHSRPVTLSPRQGLPRI
210 220 230 240 250 260
200 210 220 230 240 250
pF1KE3 PLRGIFQGAKVVRGPDWEWGSQDGGEGKPGRVVDIRGWDVETGRSVASVTWADGTTNVYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PLRGIFQGAKVVRGPDWEWGSQDGGEGKPGRVVDIRGWDVETGRSVASVTWADGTTNVYR
270 280 290 300 310 320
260 270 280 290 300 310
pF1KE3 VGYKGKVDLKCVGEAAGGFYYKDHLPRLGKPAELQRRVSADSQPFQHGDKVKCLLDTDVL
::.:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VGHKGKVDLKCVGEAAGGFYYKDHLPRLGKPAELQRRVSADSQPFQHGDKVKCLLDTDVL
330 340 350 360 370 380
320 330 340 350 360 370
pF1KE3 REMQEGHGGWNPRMAEFIGQTGTVHRITDRGDVRVQFNHETRWTFHPGALTKHHSFWVGD
:::::::::::::::: ::::::::::::::::::::::::::::::::::::::::
NP_001 REMQEGHGGWNPRMAE----TGTVHRITDRGDVRVQFNHETRWTFHPGALTKHHSFWVGD
390 400 410 420 430 440
380 390 400 410 420 430
pF1KE3 VVRVIGDLDTVKRLQAGHGEWTDDMAPALGRVGKVVKVFGDGNLRVAVAGQRWTFSPSCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VVRVIGDLDTVKRLQAGHGEWTDDMAPALGRVGKVVKVFGDGNLRVAVAGQRWTFSPSCL
450 460 470 480 490 500
440 450 460 470 480 490
pF1KE3 VAYRPEEDANLDVAERARENKSSLSVALDKLRAQKSDPEHPGRLVVEVALGNAARALGLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::
NP_001 VAYRPEEDANLDVAERARENKSSLSVALDKLRAQKSDPEHPGRLVVEVALGNAARALDLL
510 520 530 540 550 560
500 510 520 530 540 550
pF1KE3 RRRPEQVDTKNQGRTALQVAAYLGQVELIRLLLQARAGVDLPDDEGNTALHYAALGNQPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RRRPEQVDTKNQGRTALQVAAYLGQVELIRLLLQARAGVDLPDDEGNTALHYAALGNQPE
570 580 590 600 610 620
560 570 580 590 600 610
pF1KE3 ATRVLLSAGCRADAINSTQSTALHVAVQRGFLEVVRALCERGCDVNLPDAHSDTPLHSAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ATRVLLSAGCRADAINSTQSTALHVAVQRGFLEVVRALCERGCDVNLPDAHSDTPLHSAI
630 640 650 660 670 680
620 630 640 650 660 670
pF1KE3 SAGTGAGGIVEVLTEVPNIDVTATNSQGFTLLHHASLKGHALAVRKILARARQLVDAKKE
::::::.:::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SAGTGASGIVEVLTEVPNIDVTATNSQGFTLLHHASLKGHALAVRKILARARQLVDAKKE
690 700 710 720 730 740
680 690 700 710 720 730
pF1KE3 DGFTALHLAALNNHREVAQILIREGRCDVNVRNRKLQSPLHLAVQQAHVGLVPLLVDAGC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DGFTALHLAALNNHREVAQILIREGRCDVNVRNRKLQSPLHLAVQQAHVGLVPLLVDAGC
750 760 770 780 790 800
740 750 760 770 780 790
pF1KE3 SVNAEDEEGDTALHVALQRHQLLPLVADGAGGDPGPLQLLSRLQASGLPGSAELTVGAAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SVNAEDEEGDTALHVALQRHQLLPLVADGAGGDPGPLQLLSRLQASGLPGSAELTVGAAV
810 820 830 840 850 860
800 810 820 830 840 850
pF1KE3 ACFLALEGADVSYTNHRGRSPLDLAAEGRVLKALQGCAQRFRERQAGGGAAPGPRQTLGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ACFLALEGADVSYTNHRGRSPLDLAAEGRVLKALQGCAQRFRERQAGGGAAPGPRQTLGT
870 880 890 900 910 920
860 870 880 890 900 910
pF1KE3 PNTVTNLHVGAAPGPEAAECLVCSELALLVLFSPCQHRTVCEECARRMKKCIRCQVVVSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PNTVTNLHVGAAPGPEAAECLVCSELALLVLFSPCQHRTVCEECARRMKKCIRCQVVVSK
930 940 950 960 970 980
920 930 940 950 960 970
pF1KE3 KLRPDGSEVASAAPAPGPPRQLVEELQSRYRQMEERITCPICIDSHIRLVFQCGHGACAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KLRPDGSEVASAAPAPGPPRQLVEELQSRYRQMEERITCPICIDSHIRLVFQCGHGACAP
990 1000 1010 1020 1030 1040
980 990
pF1KE3 CGSALSACPICRQPIRDRIQIFV
:::::::::::::::::::::::
NP_001 CGSALSACPICRQPIRDRIQIFV
1050 1060
>>XP_011539039 (OMIM: 611141) PREDICTED: E3 ubiquitin-pr (1219 aa)
initn: 5938 init1: 5938 opt: 5942 Z-score: 3705.6 bits: 697.5 E(85289): 1.1e-199
Smith-Waterman score: 5951; 89.1% identity (92.4% similar) in 1014 aa overlap (1-999:212-1219)
10 20 30
pF1KE3 MGWKPSEARGQSQSFQASGLQPRSLKAARR
.: : :: .. : ..: : : :.::
XP_011 ERRDRPTDGLAGGPAPPSGAGGTETSGQVGVGRVGSPARLEA-SPKVSRHQGCSPGASRR
190 200 210 220 230 240
40 50 60 70
pF1KE3 ATGRPDRSRAAP----PNMDPDPQAG-------VQVGMRVVR-GVDWKWGQQDGGEGGVG
:: : .:..: : : : . .:. :. : . : . .: . ..
XP_011 PGGRLD-GRTGPEQPGPPWTPLPTGPEQPRPTWTQTPRRACRWACGWCAAWTGSGASRTA
250 260 270 280 290
80 90 100 110 120 130
pF1KE3 TVVELGRHGS--PSTPDRTVVVQWD-QGTRTNYRAGYQGAHDLLLYDNAQIGVRHPNIIC
. . .: : .. : ..::. .:::. :: . .. ::::::::
XP_011 ARAAWARWWSLAATAAPRHPTAQWSCSGTRA--RAPTTAPATR--ARTTCCCVRHPNIIC
300 310 320 330 340 350
140 150 160 170 180 190
pF1KE3 DCCKKHGLRGMRWKCRVCLDYDLCTQCYMHNKHELAHAFDRYETAHSRPVTLSPRQGLPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DCCKKHGLRGMRWKCRVCLDYDLCTQCYMHNKHELAHAFDRYETAHSRPVTLSPRQGLPR
360 370 380 390 400 410
200 210 220 230 240 250
pF1KE3 IPLRGIFQGAKVVRGPDWEWGSQDGGEGKPGRVVDIRGWDVETGRSVASVTWADGTTNVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IPLRGIFQGAKVVRGPDWEWGSQDGGEGKPGRVVDIRGWDVETGRSVASVTWADGTTNVY
420 430 440 450 460 470
260 270 280 290 300 310
pF1KE3 RVGYKGKVDLKCVGEAAGGFYYKDHLPRLGKPAELQRRVSADSQPFQHGDKVKCLLDTDV
:::.::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RVGHKGKVDLKCVGEAAGGFYYKDHLPRLGKPAELQRRVSADSQPFQHGDKVKCLLDTDV
480 490 500 510 520 530
320 330 340 350 360 370
pF1KE3 LREMQEGHGGWNPRMAEFIGQTGTVHRITDRGDVRVQFNHETRWTFHPGALTKHHSFWVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LREMQEGHGGWNPRMAEFIGQTGTVHRITDRGDVRVQFNHETRWTFHPGALTKHHSFWVG
540 550 560 570 580 590
380 390 400 410 420 430
pF1KE3 DVVRVIGDLDTVKRLQAGHGEWTDDMAPALGRVGKVVKVFGDGNLRVAVAGQRWTFSPSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DVVRVIGDLDTVKRLQAGHGEWTDDMAPALGRVGKVVKVFGDGNLRVAVAGQRWTFSPSC
600 610 620 630 640 650
440 450 460 470 480 490
pF1KE3 LVAYRPEEDANLDVAERARENKSSLSVALDKLRAQKSDPEHPGRLVVEVALGNAARALGL
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::: :
XP_011 LVAYRPEEDANLDVAERARENKSSLSVALDKLRAQKSDPEHPGRLVVEVALGNAARALDL
660 670 680 690 700 710
500 510 520 530 540 550
pF1KE3 LRRRPEQVDTKNQGRTALQVAAYLGQVELIRLLLQARAGVDLPDDEGNTALHYAALGNQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRRRPEQVDTKNQGRTALQVAAYLGQVELIRLLLQARAGVDLPDDEGNTALHYAALGNQP
720 730 740 750 760 770
560 570 580 590 600 610
pF1KE3 EATRVLLSAGCRADAINSTQSTALHVAVQRGFLEVVRALCERGCDVNLPDAHSDTPLHSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EATRVLLSAGCRADAINSTQSTALHVAVQRGFLEVVRALCERGCDVNLPDAHSDTPLHSA
780 790 800 810 820 830
620 630 640 650 660 670
pF1KE3 ISAGTGAGGIVEVLTEVPNIDVTATNSQGFTLLHHASLKGHALAVRKILARARQLVDAKK
:::::::.::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ISAGTGASGIVEVLTEVPNIDVTATNSQGFTLLHHASLKGHALAVRKILARARQLVDAKK
840 850 860 870 880 890
680 690 700 710 720 730
pF1KE3 EDGFTALHLAALNNHREVAQILIREGRCDVNVRNRKLQSPLHLAVQQAHVGLVPLLVDAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EDGFTALHLAALNNHREVAQILIREGRCDVNVRNRKLQSPLHLAVQQAHVGLVPLLVDAG
900 910 920 930 940 950
740 750 760 770 780 790
pF1KE3 CSVNAEDEEGDTALHVALQRHQLLPLVADGAGGDPGPLQLLSRLQASGLPGSAELTVGAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CSVNAEDEEGDTALHVALQRHQLLPLVADGAGGDPGPLQLLSRLQASGLPGSAELTVGAA
960 970 980 990 1000 1010
800 810 820 830 840 850
pF1KE3 VACFLALEGADVSYTNHRGRSPLDLAAEGRVLKALQGCAQRFRERQAGGGAAPGPRQTLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VACFLALEGADVSYTNHRGRSPLDLAAEGRVLKALQGCAQRFRERQAGGGAAPGPRQTLG
1020 1030 1040 1050 1060 1070
860 870 880 890 900 910
pF1KE3 TPNTVTNLHVGAAPGPEAAECLVCSELALLVLFSPCQHRTVCEECARRMKKCIRCQVVVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TPNTVTNLHVGAAPGPEAAECLVCSELALLVLFSPCQHRTVCEECARRMKKCIRCQVVVS
1080 1090 1100 1110 1120 1130
920 930 940 950 960 970
pF1KE3 KKLRPDGSEVASAAPAPGPPRQLVEELQSRYRQMEERITCPICIDSHIRLVFQCGHGACA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KKLRPDGSEVASAAPAPGPPRQLVEELQSRYRQMEERITCPICIDSHIRLVFQCGHGACA
1140 1150 1160 1170 1180 1190
980 990
pF1KE3 PCGSALSACPICRQPIRDRIQIFV
::::::::::::::::::::::::
XP_011 PCGSALSACPICRQPIRDRIQIFV
1200 1210
>>XP_016855850 (OMIM: 611141) PREDICTED: E3 ubiquitin-pr (1094 aa)
initn: 6572 init1: 5861 opt: 5879 Z-score: 3667.0 bits: 690.2 E(85289): 1.6e-197
Smith-Waterman score: 6736; 96.0% identity (96.2% similar) in 1037 aa overlap (1-999:58-1094)
10 20 30
pF1KE3 MGWKPSEARGQSQSFQASGLQPRSLKAARR
::::::::::::::::::::::::::::::
XP_016 CPVAQEGLGARSRPRVAPRSLARCGPSSRLMGWKPSEARGQSQSFQASGLQPRSLKAARR
30 40 50 60 70 80
40 50 60 70
pF1KE3 ATGRPDRSRAA--------------PPNMDPDPQAGVQVGMRVVRGVDWKWGQQDGGEGG
::::::::::: :::::::::::::::::::::::::::::::::::
XP_016 ATGRPDRSRAARPTMDPSAHRSRAAPPNMDPDPQAGVQVGMRVVRGVDWKWGQQDGGEGG
90 100 110 120 130 140
80 90 100 110 120 130
pF1KE3 VGTVVELGRHGSPSTPDRTVVVQWDQGTRTNYRAGYQGAHDLLLYDNAQIGVRHPNIICD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VGTVVELGRHGSPSTPDRTVVVQWDQGTRTNYRAGYQGAHDLLLYDNAQIGVRHPNIICD
150 160 170 180 190 200
140 150 160 170 180 190
pF1KE3 CCKKHGLRGMRWKCRVCLDYDLCTQCYMHNKHELAHAFDRYETAHSRPVTLSPRQGLPRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CCKKHGLRGMRWKCRVCLDYDLCTQCYMHNKHELAHAFDRYETAHSRPVTLSPRQGLPRI
210 220 230 240 250 260
200 210 220 230 240 250
pF1KE3 PLRGIFQGAKVVRGPDWEWGSQDGGEGKPGRVVDIRGWDVETGRSVASVTWADGTTNVYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PLRGIFQGAKVVRGPDWEWGSQDGGEGKPGRVVDIRGWDVETGRSVASVTWADGTTNVYR
270 280 290 300 310 320
260 270 280 290 300 310
pF1KE3 VGYKGKVDLKCVGEAAGGFYYKDHLPRLGKPAELQRRVSADSQPFQHGDKVKCLLDTDVL
::.:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VGHKGKVDLKCVGEAAGGFYYKDHLPRLGKPAELQRRVSADSQPFQHGDKVKCLLDTDVL
330 340 350 360 370 380
320 330 340 350 360 370
pF1KE3 REMQEGHGGWNPRMAEFIGQTGTVHRITDRGDVRVQFNHETRWTFHPGALTKHHSFWVGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 REMQEGHGGWNPRMAEFIGQTGTVHRITDRGDVRVQFNHETRWTFHPGALTKHHSFWVGD
390 400 410 420 430 440
380 390 400 410 420 430
pF1KE3 VVRVIGDLDTVKRLQAGHGEWTDDMAPALGRVGKVVKVFGDGNLRVAVAGQRWTFSPSCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VVRVIGDLDTVKRLQAGHGEWTDDMAPALGRVGKVVKVFGDGNLRVAVAGQRWTFSPSCL
450 460 470 480 490 500
440 450 460 470 480 490
pF1KE3 VAYRPEEDANLDVAERARENKSSLSVALDKLRAQKSDPEHPGRLVVEVALGNAARALGLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::
XP_016 VAYRPEEDANLDVAERARENKSSLSVALDKLRAQKSDPEHPGRLVVEVALGNAARALDLL
510 520 530 540 550 560
500 510 520 530 540 550
pF1KE3 RRRPEQVDTKNQGRTALQVAAYLGQVELIRLLLQARAGVDLPDDEGNTALHYAALGNQPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RRRPEQVDTKNQGRTALQVAAYLGQVELIRLLLQARAGVDLPDDEGNTALHYAALGNQPE
570 580 590 600 610 620
560 570 580 590 600 610
pF1KE3 ATRVLLSAGCRADAINSTQSTALHVAVQRGFLEVVRALCERGCDVNLPDAHSDTPLHSAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ATRVLLSAGCRADAINSTQSTALHVAVQRGFLEVVRALCERGCDVNLPDAHSDTPLHSAI
630 640 650 660 670 680
620 630 640 650 660 670
pF1KE3 SAGTGAGGIVEVLTEVPNIDVTATNSQGFTLLHHASLKGHALAVRKILARARQLVDAKKE
::::::.:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SAGTGASGIVEVLTEVPNIDVTATNSQGFTLLHHASLKGHALAVRKILARARQLVDAKKE
690 700 710 720 730 740
680 690 700 710 720 730
pF1KE3 DGFTALHLAALNNHREVAQILIREGRCDVNVRNRKLQSPLHLAVQQAHVGLVPLLVDAGC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DGFTALHLAALNNHREVAQILIREGRCDVNVRNRKLQSPLHLAVQQAHVGLVPLLVDAGC
750 760 770 780 790 800
740 750 760 770 780 790
pF1KE3 SVNAEDEEGDTALHVALQRHQLLPLVADGAGGDPGPLQLLSRLQASGLPGSAELTVGAAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVNAEDEEGDTALHVALQRHQLLPLVADGAGGDPGPLQLLSRLQASGLPGSAELTVGAAV
810 820 830 840 850 860
800 810 820 830 840 850
pF1KE3 ACFLALEGADVSYTNHRGRSPLDLAAEGRVLKALQGCAQRFRERQAGGGAAPGPRQTLGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ACFLALEGADVSYTNHRGRSPLDLAAEGRVLKALQGCAQRFRERQAGGGAAPGPRQTLGT
870 880 890 900 910 920
860 870 880 890
pF1KE3 PNTVTNLHVGAAPGPEAAECLVCSELALLVLFSPCQHRTVCE------------------
::::::::::::::::::::::::::::::::::::::::::
XP_016 PNTVTNLHVGAAPGPEAAECLVCSELALLVLFSPCQHRTVCEGEWGAPGWGGPASRAAAN
930 940 950 960 970 980
900 910 920 930 940 950
pF1KE3 ------ECARRMKKCIRCQVVVSKKLRPDGSEVASAAPAPGPPRQLVEELQSRYRQMEER
::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RALLFAECARRMKKCIRCQVVVSKKLRPDGSEVASAAPAPGPPRQLVEELQSRYRQMEER
990 1000 1010 1020 1030 1040
960 970 980 990
pF1KE3 ITCPICIDSHIRLVFQCGHGACAPCGSALSACPICRQPIRDRIQIFV
:::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ITCPICIDSHIRLVFQCGHGACAPCGSALSACPICRQPIRDRIQIFV
1050 1060 1070 1080 1090
>>NP_001164159 (OMIM: 611141) E3 ubiquitin-protein ligas (1005 aa)
initn: 5195 init1: 4786 opt: 4786 Z-score: 2989.1 bits: 564.6 E(85289): 9.3e-160
Smith-Waterman score: 6206; 92.0% identity (92.1% similar) in 1013 aa overlap (1-999:58-1005)
10 20 30
pF1KE3 MGWKPSEARGQSQSFQASGLQPRSLKAARR
::::::::::::::::::::::::::::::
NP_001 CPVAQEGLGARSRPRVAPRSLARCGPSSRLMGWKPSEARGQSQSFQASGLQPRSLKAARR
30 40 50 60 70 80
40 50 60 70
pF1KE3 ATGRPDRSRAA--------------PPNMDPDPQAGVQVGMRVVRGVDWKWGQQDGGEGG
::::::::::: :::::::::::::::::::::::::::::::::::
NP_001 ATGRPDRSRAARPTMDPSAHRSRAAPPNMDPDPQAGVQVGMRVVRGVDWKWGQQDGGEGG
90 100 110 120 130 140
80 90 100 110 120 130
pF1KE3 VGTVVELGRHGSPSTPDRTVVVQWDQGTRTNYRAGYQGAHDLLLYDNAQIGVRHPNIICD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VGTVVELGRHGSPSTPDRTVVVQWDQGTRTNYRAGYQGAHDLLLYDNAQIGVRHPNIICD
150 160 170 180 190 200
140 150 160 170 180 190
pF1KE3 CCKKHGLRGMRWKCRVCLDYDLCTQCYMHNKHELAHAFDRYETAHSRPVTLSPRQGLPRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CCKKHGLRGMRWKCRVCLDYDLCTQCYMHNKHELAHAFDRYETAHSRPVTLSPRQGLPRI
210 220 230 240 250 260
200 210 220 230 240 250
pF1KE3 PLRGIFQGAKVVRGPDWEWGSQDGGEGKPGRVVDIRGWDVETGRSVASVTWADGTTNVYR
::::::::::::::::::::::::
NP_001 PLRGIFQGAKVVRGPDWEWGSQDG------------------------------------
270 280 290
260 270 280 290 300 310
pF1KE3 VGYKGKVDLKCVGEAAGGFYYKDHLPRLGKPAELQRRVSADSQPFQHGDKVKCLLDTDVL
:::::::::::::::::::::::::::::::
NP_001 -----------------------------KPAELQRRVSADSQPFQHGDKVKCLLDTDVL
300 310 320
320 330 340 350 360 370
pF1KE3 REMQEGHGGWNPRMAEFIGQTGTVHRITDRGDVRVQFNHETRWTFHPGALTKHHSFWVGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 REMQEGHGGWNPRMAEFIGQTGTVHRITDRGDVRVQFNHETRWTFHPGALTKHHSFWVGD
330 340 350 360 370 380
380 390 400 410 420 430
pF1KE3 VVRVIGDLDTVKRLQAGHGEWTDDMAPALGRVGKVVKVFGDGNLRVAVAGQRWTFSPSCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VVRVIGDLDTVKRLQAGHGEWTDDMAPALGRVGKVVKVFGDGNLRVAVAGQRWTFSPSCL
390 400 410 420 430 440
440 450 460 470 480 490
pF1KE3 VAYRPEEDANLDVAERARENKSSLSVALDKLRAQKSDPEHPGRLVVEVALGNAARALGLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::
NP_001 VAYRPEEDANLDVAERARENKSSLSVALDKLRAQKSDPEHPGRLVVEVALGNAARALDLL
450 460 470 480 490 500
500 510 520 530 540 550
pF1KE3 RRRPEQVDTKNQGRTALQVAAYLGQVELIRLLLQARAGVDLPDDEGNTALHYAALGNQPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RRRPEQVDTKNQGRTALQVAAYLGQVELIRLLLQARAGVDLPDDEGNTALHYAALGNQPE
510 520 530 540 550 560
560 570 580 590 600 610
pF1KE3 ATRVLLSAGCRADAINSTQSTALHVAVQRGFLEVVRALCERGCDVNLPDAHSDTPLHSAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ATRVLLSAGCRADAINSTQSTALHVAVQRGFLEVVRALCERGCDVNLPDAHSDTPLHSAI
570 580 590 600 610 620
620 630 640 650 660 670
pF1KE3 SAGTGAGGIVEVLTEVPNIDVTATNSQGFTLLHHASLKGHALAVRKILARARQLVDAKKE
::::::.:::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SAGTGASGIVEVLTEVPNIDVTATNSQGFTLLHHASLKGHALAVRKILARARQLVDAKKE
630 640 650 660 670 680
680 690 700 710 720 730
pF1KE3 DGFTALHLAALNNHREVAQILIREGRCDVNVRNRKLQSPLHLAVQQAHVGLVPLLVDAGC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DGFTALHLAALNNHREVAQILIREGRCDVNVRNRKLQSPLHLAVQQAHVGLVPLLVDAGC
690 700 710 720 730 740
740 750 760 770 780 790
pF1KE3 SVNAEDEEGDTALHVALQRHQLLPLVADGAGGDPGPLQLLSRLQASGLPGSAELTVGAAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SVNAEDEEGDTALHVALQRHQLLPLVADGAGGDPGPLQLLSRLQASGLPGSAELTVGAAV
750 760 770 780 790 800
800 810 820 830 840 850
pF1KE3 ACFLALEGADVSYTNHRGRSPLDLAAEGRVLKALQGCAQRFRERQAGGGAAPGPRQTLGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ACFLALEGADVSYTNHRGRSPLDLAAEGRVLKALQGCAQRFRERQAGGGAAPGPRQTLGT
810 820 830 840 850 860
860 870 880 890 900 910
pF1KE3 PNTVTNLHVGAAPGPEAAECLVCSELALLVLFSPCQHRTVCEECARRMKKCIRCQVVVSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PNTVTNLHVGAAPGPEAAECLVCSELALLVLFSPCQHRTVCEECARRMKKCIRCQVVVSK
870 880 890 900 910 920
920 930 940 950 960 970
pF1KE3 KLRPDGSEVASAAPAPGPPRQLVEELQSRYRQMEERITCPICIDSHIRLVFQCGHGACAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KLRPDGSEVASAAPAPGPPRQLVEELQSRYRQMEERITCPICIDSHIRLVFQCGHGACAP
930 940 950 960 970 980
980 990
pF1KE3 CGSALSACPICRQPIRDRIQIFV
:::::::::::::::::::::::
NP_001 CGSALSACPICRQPIRDRIQIFV
990 1000
>>XP_016855842 (OMIM: 611141) PREDICTED: E3 ubiquitin-pr (1276 aa)
initn: 5127 init1: 4416 opt: 4443 Z-score: 2775.3 bits: 525.4 E(85289): 7.6e-148
Smith-Waterman score: 5634; 83.9% identity (87.2% similar) in 1046 aa overlap (1-974:212-1251)
10 20 30
pF1KE3 MGWKPSEARGQSQSFQASGLQPRSLKAARR
.: : :: .. : ..: : : :.::
XP_016 ERRDRPTDGLAGGPAPPSGAGGTETSGQVGVGRVGSPARLEA-SPKVSRHQGCSPGASRR
190 200 210 220 230 240
40 50 60 70
pF1KE3 ATGRPDRSRAAP----PNMDPDPQAG-------VQVGMRVVR-GVDWKWGQQDGGEGGVG
:: : .:..: : : : . .:. :. : . : . .: . ..
XP_016 PGGRLD-GRTGPEQPGPPWTPLPTGPEQPRPTWTQTPRRACRWACGWCAAWTGSGASRTA
250 260 270 280 290
80 90 100 110 120 130
pF1KE3 TVVELGRHGS--PSTPDRTVVVQWD-QGTRTNYRAGYQGAHDLLLYDNAQIGVRHPNIIC
. . .: : .. : ..::. .:::. :: . .. ::::::::
XP_016 ARAAWARWWSLAATAAPRHPTAQWSCSGTRA--RA--PTTAPATRARTTCCCVRHPNIIC
300 310 320 330 340 350
140 150 160 170 180 190
pF1KE3 DCCKKHGLRGMRWKCRVCLDYDLCTQCYMHNKHELAHAFDRYETAHSRPVTLSPRQGLPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DCCKKHGLRGMRWKCRVCLDYDLCTQCYMHNKHELAHAFDRYETAHSRPVTLSPRQGLPR
360 370 380 390 400 410
200 210 220 230 240 250
pF1KE3 IPLRGIFQGAKVVRGPDWEWGSQDGGEGKPGRVVDIRGWDVETGRSVASVTWADGTTNVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IPLRGIFQGAKVVRGPDWEWGSQDGGEGKPGRVVDIRGWDVETGRSVASVTWADGTTNVY
420 430 440 450 460 470
260 270 280 290 300 310
pF1KE3 RVGYKGKVDLKCVGEAAGGFYYKDHLPRLGKPAELQRRVSADSQPFQHGDKVKCLLDTDV
:::.::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RVGHKGKVDLKCVGEAAGGFYYKDHLPRLGKPAELQRRVSADSQPFQHGDKVKCLLDTDV
480 490 500 510 520 530
320 330 340 350 360 370
pF1KE3 LREMQEGHGGWNPRMAEFIGQTGTVHRITDRGDVRVQFNHETRWTFHPGALTKHHSFWVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LREMQEGHGGWNPRMAEFIGQTGTVHRITDRGDVRVQFNHETRWTFHPGALTKHHSFWVG
540 550 560 570 580 590
380 390 400 410 420 430
pF1KE3 DVVRVIGDLDTVKRLQAGHGEWTDDMAPALGRVGKVVKVFGDGNLRVAVAGQRWTFSPSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DVVRVIGDLDTVKRLQAGHGEWTDDMAPALGRVGKVVKVFGDGNLRVAVAGQRWTFSPSC
600 610 620 630 640 650
440 450 460 470 480 490
pF1KE3 LVAYRPEEDANLDVAERARENKSSLSVALDKLRAQKSDPEHPGRLVVEVALGNAARALGL
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::: :
XP_016 LVAYRPEEDANLDVAERARENKSSLSVALDKLRAQKSDPEHPGRLVVEVALGNAARALDL
660 670 680 690 700 710
500 510 520 530 540 550
pF1KE3 LRRRPEQVDTKNQGRTALQVAAYLGQVELIRLLLQARAGVDLPDDEGNTALHYAALGNQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRRRPEQVDTKNQGRTALQVAAYLGQVELIRLLLQARAGVDLPDDEGNTALHYAALGNQP
720 730 740 750 760 770
560 570 580 590 600 610
pF1KE3 EATRVLLSAGCRADAINSTQSTALHVAVQRGFLEVVRALCERGCDVNLPDAHSDTPLHSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EATRVLLSAGCRADAINSTQSTALHVAVQRGFLEVVRALCERGCDVNLPDAHSDTPLHSA
780 790 800 810 820 830
620 630 640 650 660 670
pF1KE3 ISAGTGAGGIVEVLTEVPNIDVTATNSQGFTLLHHASLKGHALAVRKILARARQLVDAKK
:::::::.::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ISAGTGASGIVEVLTEVPNIDVTATNSQGFTLLHHASLKGHALAVRKILARARQLVDAKK
840 850 860 870 880 890
680 690 700 710 720 730
pF1KE3 EDGFTALHLAALNNHREVAQILIREGRCDVNVRNRKLQSPLHLAVQQAHVGLVPLLVDAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EDGFTALHLAALNNHREVAQILIREGRCDVNVRNRKLQSPLHLAVQQAHVGLVPLLVDAG
900 910 920 930 940 950
740 750 760 770
pF1KE3 CSVNAEDEEGDTALHVALQRHQLLPLVADGAGGDPGPLQLLSR-----------------
:::::::::::::::::::::::::::::::::::::::::::
XP_016 CSVNAEDEEGDTALHVALQRHQLLPLVADGAGGDPGPLQLLSRTWGAGCWGCQVPGDASL
960 970 980 990 1000 1010
780 790 800 810 820
pF1KE3 ----------------LQASGLPGSAELTVGAAVACFLALEGADVSYTNHRGRSPLDLAA
::::::::::::::::::::::::::::::::::::::::::::
XP_016 GPAPAPALTGVCPAAQLQASGLPGSAELTVGAAVACFLALEGADVSYTNHRGRSPLDLAA
1020 1030 1040 1050 1060 1070
830 840 850 860 870 880
pF1KE3 EGRVLKALQGCAQRFRERQAGGGAAPGPRQTLGTPNTVTNLHVGAAPGPEAAECLVCSEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EGRVLKALQGCAQRFRERQAGGGAAPGPRQTLGTPNTVTNLHVGAAPGPEAAECLVCSEL
1080 1090 1100 1110 1120 1130
890 900 910
pF1KE3 ALLVLFSPCQHRTVCE------------------------ECARRMKKCIRCQVVVSKKL
:::::::::::::::: ::::::::::::::::::::
XP_016 ALLVLFSPCQHRTVCEGEWGAPGWGGPASRAAANRALLFAECARRMKKCIRCQVVVSKKL
1140 1150 1160 1170 1180 1190
920 930 940 950 960 970
pF1KE3 RPDGSEVASAAPAPGPPRQLVEELQSRYRQMEERITCPICIDSHIRLVFQCGHGACAPCG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RPDGSEVASAAPAPGPPRQLVEELQSRYRQMEERITCPICIDSHIRLVFQCGHGACAPCG
1200 1210 1220 1230 1240 1250
980 990
pF1KE3 SALSACPICRQPIRDRIQIFV
XP_016 SALSACPICRQPIRDRIQIFV
1260 1270
>>XP_016855855 (OMIM: 611141) PREDICTED: E3 ubiquitin-pr (911 aa)
initn: 4981 init1: 4270 opt: 4293 Z-score: 2683.6 bits: 507.9 E(85289): 9.7e-143
Smith-Waterman score: 5475; 93.2% identity (93.5% similar) in 886 aa overlap (146-974:1-886)
120 130 140 150 160 170
pF1KE3 HDLLLYDNAQIGVRHPNIICDCCKKHGLRGMRWKCRVCLDYDLCTQCYMHNKHELAHAFD
::::::::::::::::::::::::::::::
XP_016 MRWKCRVCLDYDLCTQCYMHNKHELAHAFD
10 20 30
180 190 200 210 220 230
pF1KE3 RYETAHSRPVTLSPRQGLPRIPLRGIFQGAKVVRGPDWEWGSQDGGEGKPGRVVDIRGWD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RYETAHSRPVTLSPRQGLPRIPLRGIFQGAKVVRGPDWEWGSQDGGEGKPGRVVDIRGWD
40 50 60 70 80 90
240 250 260 270 280 290
pF1KE3 VETGRSVASVTWADGTTNVYRVGYKGKVDLKCVGEAAGGFYYKDHLPRLGKPAELQRRVS
:::::::::::::::::::::::.::::::::::::::::::::::::::::::::::::
XP_016 VETGRSVASVTWADGTTNVYRVGHKGKVDLKCVGEAAGGFYYKDHLPRLGKPAELQRRVS
100 110 120 130 140 150
300 310 320 330 340 350
pF1KE3 ADSQPFQHGDKVKCLLDTDVLREMQEGHGGWNPRMAEFIGQTGTVHRITDRGDVRVQFNH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ADSQPFQHGDKVKCLLDTDVLREMQEGHGGWNPRMAEFIGQTGTVHRITDRGDVRVQFNH
160 170 180 190 200 210
360 370 380 390 400 410
pF1KE3 ETRWTFHPGALTKHHSFWVGDVVRVIGDLDTVKRLQAGHGEWTDDMAPALGRVGKVVKVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ETRWTFHPGALTKHHSFWVGDVVRVIGDLDTVKRLQAGHGEWTDDMAPALGRVGKVVKVF
220 230 240 250 260 270
420 430 440 450 460 470
pF1KE3 GDGNLRVAVAGQRWTFSPSCLVAYRPEEDANLDVAERARENKSSLSVALDKLRAQKSDPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GDGNLRVAVAGQRWTFSPSCLVAYRPEEDANLDVAERARENKSSLSVALDKLRAQKSDPE
280 290 300 310 320 330
480 490 500 510 520 530
pF1KE3 HPGRLVVEVALGNAARALGLLRRRPEQVDTKNQGRTALQVAAYLGQVELIRLLLQARAGV
:::::::::::::::::: :::::::::::::::::::::::::::::::::::::::::
XP_016 HPGRLVVEVALGNAARALDLLRRRPEQVDTKNQGRTALQVAAYLGQVELIRLLLQARAGV
340 350 360 370 380 390
540 550 560 570 580 590
pF1KE3 DLPDDEGNTALHYAALGNQPEATRVLLSAGCRADAINSTQSTALHVAVQRGFLEVVRALC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DLPDDEGNTALHYAALGNQPEATRVLLSAGCRADAINSTQSTALHVAVQRGFLEVVRALC
400 410 420 430 440 450
600 610 620 630 640 650
pF1KE3 ERGCDVNLPDAHSDTPLHSAISAGTGAGGIVEVLTEVPNIDVTATNSQGFTLLHHASLKG
:::::::::::::::::::::::::::.::::::::::::::::::::::::::::::::
XP_016 ERGCDVNLPDAHSDTPLHSAISAGTGASGIVEVLTEVPNIDVTATNSQGFTLLHHASLKG
460 470 480 490 500 510
660 670 680 690 700 710
pF1KE3 HALAVRKILARARQLVDAKKEDGFTALHLAALNNHREVAQILIREGRCDVNVRNRKLQSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HALAVRKILARARQLVDAKKEDGFTALHLAALNNHREVAQILIREGRCDVNVRNRKLQSP
520 530 540 550 560 570
720 730 740 750 760 770
pF1KE3 LHLAVQQAHVGLVPLLVDAGCSVNAEDEEGDTALHVALQRHQLLPLVADGAGGDPGPLQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LHLAVQQAHVGLVPLLVDAGCSVNAEDEEGDTALHVALQRHQLLPLVADGAGGDPGPLQL
580 590 600 610 620 630
780 790 800
pF1KE3 LSR---------------------------------LQASGLPGSAELTVGAAVACFLAL
::: ::::::::::::::::::::::::
XP_016 LSRTWGAGCWGCQVPGDASLGPAPAPALTGVCPAAQLQASGLPGSAELTVGAAVACFLAL
640 650 660 670 680 690
810 820 830 840 850 860
pF1KE3 EGADVSYTNHRGRSPLDLAAEGRVLKALQGCAQRFRERQAGGGAAPGPRQTLGTPNTVTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EGADVSYTNHRGRSPLDLAAEGRVLKALQGCAQRFRERQAGGGAAPGPRQTLGTPNTVTN
700 710 720 730 740 750
870 880 890
pF1KE3 LHVGAAPGPEAAECLVCSELALLVLFSPCQHRTVCE------------------------
::::::::::::::::::::::::::::::::::::
XP_016 LHVGAAPGPEAAECLVCSELALLVLFSPCQHRTVCEGEWGAPGWGGPASRAAANRALLFA
760 770 780 790 800 810
900 910 920 930 940 950
pF1KE3 ECARRMKKCIRCQVVVSKKLRPDGSEVASAAPAPGPPRQLVEELQSRYRQMEERITCPIC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ECARRMKKCIRCQVVVSKKLRPDGSEVASAAPAPGPPRQLVEELQSRYRQMEERITCPIC
820 830 840 850 860 870
960 970 980 990
pF1KE3 IDSHIRLVFQCGHGACAPCGSALSACPICRQPIRDRIQIFV
::::::::::::::::
XP_016 IDSHIRLVFQCGHGACAPCGSALSACPICRQPIRDRIQIFV
880 890 900 910
>>XP_006710435 (OMIM: 611141) PREDICTED: E3 ubiquitin-pr (1034 aa)
initn: 4614 init1: 4195 opt: 4195 Z-score: 2622.3 bits: 496.8 E(85289): 2.5e-139
Smith-Waterman score: 6459; 94.8% identity (95.0% similar) in 1013 aa overlap (1-999:58-1034)
10 20 30
pF1KE3 MGWKPSEARGQSQSFQASGLQPRSLKAARR
::::::::::::::::::::::::::::::
XP_006 CPVAQEGLGARSRPRVAPRSLARCGPSSRLMGWKPSEARGQSQSFQASGLQPRSLKAARR
30 40 50 60 70 80
40 50 60 70
pF1KE3 ATGRPDRSRAA--------------PPNMDPDPQAGVQVGMRVVRGVDWKWGQQDGGEGG
::::::::::: :::::::::::::::::::::::::::::::::::
XP_006 ATGRPDRSRAARPTMDPSAHRSRAAPPNMDPDPQAGVQVGMRVVRGVDWKWGQQDGGEGG
90 100 110 120 130 140
80 90 100 110 120 130
pF1KE3 VGTVVELGRHGSPSTPDRTVVVQWDQGTRTNYRAGYQGAHDLLLYDNAQIGVRHPNIICD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VGTVVELGRHGSPSTPDRTVVVQWDQGTRTNYRAGYQGAHDLLLYDNAQIGVRHPNIICD
150 160 170 180 190 200
140 150 160 170 180 190
pF1KE3 CCKKHGLRGMRWKCRVCLDYDLCTQCYMHNKHELAHAFDRYETAHSRPVTLSPRQGLPRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 CCKKHGLRGMRWKCRVCLDYDLCTQCYMHNKHELAHAFDRYETAHSRPVTLSPRQGLPRI
210 220 230 240 250 260
200 210 220 230 240 250
pF1KE3 PLRGIFQGAKVVRGPDWEWGSQDGGEGKPGRVVDIRGWDVETGRSVASVTWADGTTNVYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PLRGIFQGAKVVRGPDWEWGSQDGGEGKPGRVVDIRGWDVETGRSVASVTWADGTTNVYR
270 280 290 300 310 320
260 270 280 290 300 310
pF1KE3 VGYKGKVDLKCVGEAAGGFYYKDHLPRLGKPAELQRRVSADSQPFQHGDKVKCLLDTDVL
::.:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VGHKGKVDLKCVGEAAGGFYYKDHLPRLGKPAELQRRVSADSQPFQHGDKVKCLLDTDVL
330 340 350 360 370 380
320 330 340 350 360 370
pF1KE3 REMQEGHGGWNPRMAEFIGQTGTVHRITDRGDVRVQFNHETRWTFHPGALTKHHSFWVGD
:::::::::::::::: ::::::::
XP_006 REMQEGHGGWNPRMAE------------------------------------HHSFWVGD
390 400 410
380 390 400 410 420 430
pF1KE3 VVRVIGDLDTVKRLQAGHGEWTDDMAPALGRVGKVVKVFGDGNLRVAVAGQRWTFSPSCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VVRVIGDLDTVKRLQAGHGEWTDDMAPALGRVGKVVKVFGDGNLRVAVAGQRWTFSPSCL
420 430 440 450 460 470
440 450 460 470 480 490
pF1KE3 VAYRPEEDANLDVAERARENKSSLSVALDKLRAQKSDPEHPGRLVVEVALGNAARALGLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::
XP_006 VAYRPEEDANLDVAERARENKSSLSVALDKLRAQKSDPEHPGRLVVEVALGNAARALDLL
480 490 500 510 520 530
500 510 520 530 540 550
pF1KE3 RRRPEQVDTKNQGRTALQVAAYLGQVELIRLLLQARAGVDLPDDEGNTALHYAALGNQPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RRRPEQVDTKNQGRTALQVAAYLGQVELIRLLLQARAGVDLPDDEGNTALHYAALGNQPE
540 550 560 570 580 590
560 570 580 590 600 610
pF1KE3 ATRVLLSAGCRADAINSTQSTALHVAVQRGFLEVVRALCERGCDVNLPDAHSDTPLHSAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ATRVLLSAGCRADAINSTQSTALHVAVQRGFLEVVRALCERGCDVNLPDAHSDTPLHSAI
600 610 620 630 640 650
620 630 640 650 660 670
pF1KE3 SAGTGAGGIVEVLTEVPNIDVTATNSQGFTLLHHASLKGHALAVRKILARARQLVDAKKE
::::::.:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SAGTGASGIVEVLTEVPNIDVTATNSQGFTLLHHASLKGHALAVRKILARARQLVDAKKE
660 670 680 690 700 710
680 690 700 710 720 730
pF1KE3 DGFTALHLAALNNHREVAQILIREGRCDVNVRNRKLQSPLHLAVQQAHVGLVPLLVDAGC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DGFTALHLAALNNHREVAQILIREGRCDVNVRNRKLQSPLHLAVQQAHVGLVPLLVDAGC
720 730 740 750 760 770
740 750 760 770 780 790
pF1KE3 SVNAEDEEGDTALHVALQRHQLLPLVADGAGGDPGPLQLLSRLQASGLPGSAELTVGAAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SVNAEDEEGDTALHVALQRHQLLPLVADGAGGDPGPLQLLSRLQASGLPGSAELTVGAAV
780 790 800 810 820 830
800 810 820 830 840 850
pF1KE3 ACFLALEGADVSYTNHRGRSPLDLAAEGRVLKALQGCAQRFRERQAGGGAAPGPRQTLGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ACFLALEGADVSYTNHRGRSPLDLAAEGRVLKALQGCAQRFRERQAGGGAAPGPRQTLGT
840 850 860 870 880 890
860 870 880 890 900 910
pF1KE3 PNTVTNLHVGAAPGPEAAECLVCSELALLVLFSPCQHRTVCEECARRMKKCIRCQVVVSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PNTVTNLHVGAAPGPEAAECLVCSELALLVLFSPCQHRTVCEECARRMKKCIRCQVVVSK
900 910 920 930 940 950
920 930 940 950 960 970
pF1KE3 KLRPDGSEVASAAPAPGPPRQLVEELQSRYRQMEERITCPICIDSHIRLVFQCGHGACAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KLRPDGSEVASAAPAPGPPRQLVEELQSRYRQMEERITCPICIDSHIRLVFQCGHGACAP
960 970 980 990 1000 1010
980 990
pF1KE3 CGSALSACPICRQPIRDRIQIFV
:::::::::::::::::::::::
XP_006 CGSALSACPICRQPIRDRIQIFV
1020 1030
>>XP_011539044 (OMIM: 611141) PREDICTED: E3 ubiquitin-pr (1183 aa)
initn: 4195 init1: 4195 opt: 4195 Z-score: 2621.7 bits: 496.9 E(85289): 2.7e-139
Smith-Waterman score: 5616; 85.5% identity (88.9% similar) in 1014 aa overlap (1-999:212-1183)
10 20 30
pF1KE3 MGWKPSEARGQSQSFQASGLQPRSLKAARR
.: : :: .. : ..: : : :.::
XP_011 ERRDRPTDGLAGGPAPPSGAGGTETSGQVGVGRVGSPARLEA-SPKVSRHQGCSPGASRR
190 200 210 220 230 240
40 50 60 70
pF1KE3 ATGRPDRSRAAP----PNMDPDPQAG-------VQVGMRVVR-GVDWKWGQQDGGEGGVG
:: : .:..: : : : . .:. :. : . : . .: . ..
XP_011 PGGRLD-GRTGPEQPGPPWTPLPTGPEQPRPTWTQTPRRACRWACGWCAAWTGSGASRTA
250 260 270 280 290
80 90 100 110 120 130
pF1KE3 TVVELGRHGS--PSTPDRTVVVQWD-QGTRTNYRAGYQGAHDLLLYDNAQIGVRHPNIIC
. . .: : .. : ..::. .:::. :: . .. ::::::::
XP_011 ARAAWARWWSLAATAAPRHPTAQWSCSGTRA--RAPTTAPATR--ARTTCCCVRHPNIIC
300 310 320 330 340 350
140 150 160 170 180 190
pF1KE3 DCCKKHGLRGMRWKCRVCLDYDLCTQCYMHNKHELAHAFDRYETAHSRPVTLSPRQGLPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DCCKKHGLRGMRWKCRVCLDYDLCTQCYMHNKHELAHAFDRYETAHSRPVTLSPRQGLPR
360 370 380 390 400 410
200 210 220 230 240 250
pF1KE3 IPLRGIFQGAKVVRGPDWEWGSQDGGEGKPGRVVDIRGWDVETGRSVASVTWADGTTNVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IPLRGIFQGAKVVRGPDWEWGSQDGGEGKPGRVVDIRGWDVETGRSVASVTWADGTTNVY
420 430 440 450 460 470
260 270 280 290 300 310
pF1KE3 RVGYKGKVDLKCVGEAAGGFYYKDHLPRLGKPAELQRRVSADSQPFQHGDKVKCLLDTDV
:::.::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RVGHKGKVDLKCVGEAAGGFYYKDHLPRLGKPAELQRRVSADSQPFQHGDKVKCLLDTDV
480 490 500 510 520 530
320 330 340 350 360 370
pF1KE3 LREMQEGHGGWNPRMAEFIGQTGTVHRITDRGDVRVQFNHETRWTFHPGALTKHHSFWVG
::::::::::::::::: :::::::
XP_011 LREMQEGHGGWNPRMAE------------------------------------HHSFWVG
540 550
380 390 400 410 420 430
pF1KE3 DVVRVIGDLDTVKRLQAGHGEWTDDMAPALGRVGKVVKVFGDGNLRVAVAGQRWTFSPSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DVVRVIGDLDTVKRLQAGHGEWTDDMAPALGRVGKVVKVFGDGNLRVAVAGQRWTFSPSC
560 570 580 590 600 610
440 450 460 470 480 490
pF1KE3 LVAYRPEEDANLDVAERARENKSSLSVALDKLRAQKSDPEHPGRLVVEVALGNAARALGL
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::: :
XP_011 LVAYRPEEDANLDVAERARENKSSLSVALDKLRAQKSDPEHPGRLVVEVALGNAARALDL
620 630 640 650 660 670
500 510 520 530 540 550
pF1KE3 LRRRPEQVDTKNQGRTALQVAAYLGQVELIRLLLQARAGVDLPDDEGNTALHYAALGNQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRRRPEQVDTKNQGRTALQVAAYLGQVELIRLLLQARAGVDLPDDEGNTALHYAALGNQP
680 690 700 710 720 730
560 570 580 590 600 610
pF1KE3 EATRVLLSAGCRADAINSTQSTALHVAVQRGFLEVVRALCERGCDVNLPDAHSDTPLHSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EATRVLLSAGCRADAINSTQSTALHVAVQRGFLEVVRALCERGCDVNLPDAHSDTPLHSA
740 750 760 770 780 790
620 630 640 650 660 670
pF1KE3 ISAGTGAGGIVEVLTEVPNIDVTATNSQGFTLLHHASLKGHALAVRKILARARQLVDAKK
:::::::.::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ISAGTGASGIVEVLTEVPNIDVTATNSQGFTLLHHASLKGHALAVRKILARARQLVDAKK
800 810 820 830 840 850
680 690 700 710 720 730
pF1KE3 EDGFTALHLAALNNHREVAQILIREGRCDVNVRNRKLQSPLHLAVQQAHVGLVPLLVDAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EDGFTALHLAALNNHREVAQILIREGRCDVNVRNRKLQSPLHLAVQQAHVGLVPLLVDAG
860 870 880 890 900 910
740 750 760 770 780 790
pF1KE3 CSVNAEDEEGDTALHVALQRHQLLPLVADGAGGDPGPLQLLSRLQASGLPGSAELTVGAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CSVNAEDEEGDTALHVALQRHQLLPLVADGAGGDPGPLQLLSRLQASGLPGSAELTVGAA
920 930 940 950 960 970
800 810 820 830 840 850
pF1KE3 VACFLALEGADVSYTNHRGRSPLDLAAEGRVLKALQGCAQRFRERQAGGGAAPGPRQTLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VACFLALEGADVSYTNHRGRSPLDLAAEGRVLKALQGCAQRFRERQAGGGAAPGPRQTLG
980 990 1000 1010 1020 1030
860 870 880 890 900 910
pF1KE3 TPNTVTNLHVGAAPGPEAAECLVCSELALLVLFSPCQHRTVCEECARRMKKCIRCQVVVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TPNTVTNLHVGAAPGPEAAECLVCSELALLVLFSPCQHRTVCEECARRMKKCIRCQVVVS
1040 1050 1060 1070 1080 1090
920 930 940 950 960 970
pF1KE3 KKLRPDGSEVASAAPAPGPPRQLVEELQSRYRQMEERITCPICIDSHIRLVFQCGHGACA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KKLRPDGSEVASAAPAPGPPRQLVEELQSRYRQMEERITCPICIDSHIRLVFQCGHGACA
1100 1110 1120 1130 1140 1150
980 990
pF1KE3 PCGSALSACPICRQPIRDRIQIFV
::::::::::::::::::::::::
XP_011 PCGSALSACPICRQPIRDRIQIFV
1160 1170 1180
999 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 03:45:49 2016 done: Mon Nov 7 03:45:51 2016
Total Scan time: 15.310 Total Display time: 0.470
Function used was FASTA [36.3.4 Apr, 2011]