Result of FASTA (ccds) for
pFN21AE3525
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3525, 249 aa
1>>>pF1KE3525 249 - 249 aa - 249 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.8845+/-0.00109; mu= 11.9248+/- 0.065
mean_var=106.5547+/-22.320, 0's: 0 Z-trim(106.0): 175 B-trim: 181 in 1/49
Lambda= 0.124248
statistics sampled from 8508 (8724) to 8508 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.63), E-opt: 0.2 (0.268), width: 16
Scan time: 1.980
The best scores are: opt bits E(32554)
CCDS5397.1 HNRNPA2B1 gene_id:3181|Hs108|chr7 ( 341) 1215 228.6 4.2e-60
CCDS43557.1 HNRNPA2B1 gene_id:3181|Hs108|chr7 ( 353) 1203 226.5 1.9e-59
CCDS41793.1 HNRNPA1 gene_id:3178|Hs108|chr12 ( 320) 1012 192.2 3.6e-49
CCDS44909.1 HNRNPA1 gene_id:3178|Hs108|chr12 ( 372) 1012 192.3 4e-49
CCDS82536.1 HNRNPA3 gene_id:220988|Hs108|chr2 ( 356) 996 189.4 2.8e-48
CCDS2273.1 HNRNPA3 gene_id:220988|Hs108|chr2 ( 378) 996 189.4 3e-48
CCDS31980.1 HNRNPA1L2 gene_id:144983|Hs108|chr13 ( 320) 986 187.5 9.1e-48
CCDS4193.1 HNRNPA0 gene_id:10949|Hs108|chr5 ( 305) 692 134.8 6.4e-32
CCDS9196.1 MSI1 gene_id:4440|Hs108|chr12 ( 362) 528 105.5 5.2e-23
CCDS3591.1 HNRNPD gene_id:3184|Hs108|chr4 ( 336) 527 105.3 5.5e-23
CCDS3590.1 HNRNPD gene_id:3184|Hs108|chr4 ( 306) 525 104.9 6.6e-23
CCDS3592.1 HNRNPD gene_id:3184|Hs108|chr4 ( 355) 525 104.9 7.4e-23
CCDS11597.1 MSI2 gene_id:124540|Hs108|chr17 ( 251) 517 103.4 1.6e-22
CCDS34310.1 HNRNPAB gene_id:3182|Hs108|chr5 ( 285) 517 103.4 1.7e-22
CCDS11596.1 MSI2 gene_id:124540|Hs108|chr17 ( 328) 517 103.5 1.9e-22
CCDS34309.1 HNRNPAB gene_id:3182|Hs108|chr5 ( 332) 517 103.5 1.9e-22
CCDS82168.1 MSI2 gene_id:124540|Hs108|chr17 ( 324) 511 102.4 3.9e-22
CCDS75153.1 HNRNPDL gene_id:9987|Hs108|chr4 ( 363) 490 98.7 5.8e-21
CCDS3593.1 HNRNPDL gene_id:9987|Hs108|chr4 ( 420) 490 98.7 6.5e-21
>>CCDS5397.1 HNRNPA2B1 gene_id:3181|Hs108|chr7 (341 aa)
initn: 1215 init1: 1215 opt: 1215 Z-score: 1192.5 bits: 228.6 E(32554): 4.2e-60
Smith-Waterman score: 1215; 100.0% identity (100.0% similar) in 183 aa overlap (1-183:1-183)
10 20 30 40 50 60
pF1KE3 MEREKEQFRKLFIGGLSFETTEESLRNYYEQWGKLTDCVVMRDPASKRSRGFGFVTFSSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS53 MEREKEQFRKLFIGGLSFETTEESLRNYYEQWGKLTDCVVMRDPASKRSRGFGFVTFSSM
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 AEVDAAMAARPHSIDGRVVEPKRAVAREESGKPGAHVTVKKLFVGGIKEDTEEHHLRDYF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS53 AEVDAAMAARPHSIDGRVVEPKRAVAREESGKPGAHVTVKKLFVGGIKEDTEEHHLRDYF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 EEYGKIDTIEIITDRQSGKKRGFGFVTFDDHDPVDKIVLQKYHTINGHNAEVRKALSRQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS53 EEYGKIDTIEIITDRQSGKKRGFGFVTFDDHDPVDKIVLQKYHTINGHNAEVRKALSRQE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 MQEDLEVAILEVAPVMEEEEEDMVVEDLDMATRVGATEVVMTTMEEEIMEVEITMILEII
:::
CCDS53 MQEVQSSRSGRGGNFGFGDSRGGGGNFGPGPGSNFRGGSDGYGSGRGFGDGYNGYGGGPG
190 200 210 220 230 240
>>CCDS43557.1 HNRNPA2B1 gene_id:3181|Hs108|chr7 (353 aa)
initn: 1203 init1: 1203 opt: 1203 Z-score: 1180.7 bits: 226.5 E(32554): 1.9e-59
Smith-Waterman score: 1203; 99.5% identity (100.0% similar) in 182 aa overlap (2-183:14-195)
10 20 30 40
pF1KE3 MEREKEQFRKLFIGGLSFETTEESLRNYYEQWGKLTDCVVMRDPASKR
.::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 MEKTLETVPLERKKREKEQFRKLFIGGLSFETTEESLRNYYEQWGKLTDCVVMRDPASKR
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE3 SRGFGFVTFSSMAEVDAAMAARPHSIDGRVVEPKRAVAREESGKPGAHVTVKKLFVGGIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 SRGFGFVTFSSMAEVDAAMAARPHSIDGRVVEPKRAVAREESGKPGAHVTVKKLFVGGIK
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE3 EDTEEHHLRDYFEEYGKIDTIEIITDRQSGKKRGFGFVTFDDHDPVDKIVLQKYHTINGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS43 EDTEEHHLRDYFEEYGKIDTIEIITDRQSGKKRGFGFVTFDDHDPVDKIVLQKYHTINGH
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE3 NAEVRKALSRQEMQEDLEVAILEVAPVMEEEEEDMVVEDLDMATRVGATEVVMTTMEEEI
:::::::::::::::
CCDS43 NAEVRKALSRQEMQEVQSSRSGRGGNFGFGDSRGGGGNFGPGPGSNFRGGSDGYGSGRGF
190 200 210 220 230 240
>>CCDS41793.1 HNRNPA1 gene_id:3178|Hs108|chr12 (320 aa)
initn: 1012 init1: 1012 opt: 1012 Z-score: 996.2 bits: 192.2 E(32554): 3.6e-49
Smith-Waterman score: 1012; 80.4% identity (95.0% similar) in 179 aa overlap (3-181:8-186)
10 20 30 40 50
pF1KE3 MEREKEQFRKLFIGGLSFETTEESLRNYYEQWGKLTDCVVMRDPASKRSRGFGFV
.: ::.:::::::::::::.::::...:::: :::::::::: .:::::::::
CCDS41 MSKSESPKEPEQLRKLFIGGLSFETTDESLRSHFEQWGTLTDCVVMRDPNTKRSRGFGFV
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE3 TFSSMAEVDAAMAARPHSIDGRVVEPKRAVAREESGKPGAHVTVKKLFVGGIKEDTEEHH
:.... :::::: ::::..:::::::::::.::.: .::::.::::.:::::::::::::
CCDS41 TYATVEEVDAAMNARPHKVDGRVVEPKRAVSREDSQRPGAHLTVKKIFVGGIKEDTEEHH
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE3 LRDYFEEYGKIDTIEIITDRQSGKKRGFGFVTFDDHDPVDKIVLQKYHTINGHNAEVRKA
::::::.::::..:::.::: :::::::.:::::::: :::::.:::::.:::: :::::
CCDS41 LRDYFEQYGKIEVIEIMTDRGSGKKRGFAFVTFDDHDSVDKIVIQKYHTVNGHNCEVRKA
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE3 LSRQEMQEDLEVAILEVAPVMEEEEEDMVVEDLDMATRVGATEVVMTTMEEEIMEVEITM
::.:::
CCDS41 LSKQEMASASSSQRGRSGSGNFGGGRGGGFGGNDNFGRGGNFSGRGGFGGSRGGGGYGGS
190 200 210 220 230 240
>>CCDS44909.1 HNRNPA1 gene_id:3178|Hs108|chr12 (372 aa)
initn: 1012 init1: 1012 opt: 1012 Z-score: 995.4 bits: 192.3 E(32554): 4e-49
Smith-Waterman score: 1012; 80.4% identity (95.0% similar) in 179 aa overlap (3-181:8-186)
10 20 30 40 50
pF1KE3 MEREKEQFRKLFIGGLSFETTEESLRNYYEQWGKLTDCVVMRDPASKRSRGFGFV
.: ::.:::::::::::::.::::...:::: :::::::::: .:::::::::
CCDS44 MSKSESPKEPEQLRKLFIGGLSFETTDESLRSHFEQWGTLTDCVVMRDPNTKRSRGFGFV
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE3 TFSSMAEVDAAMAARPHSIDGRVVEPKRAVAREESGKPGAHVTVKKLFVGGIKEDTEEHH
:.... :::::: ::::..:::::::::::.::.: .::::.::::.:::::::::::::
CCDS44 TYATVEEVDAAMNARPHKVDGRVVEPKRAVSREDSQRPGAHLTVKKIFVGGIKEDTEEHH
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE3 LRDYFEEYGKIDTIEIITDRQSGKKRGFGFVTFDDHDPVDKIVLQKYHTINGHNAEVRKA
::::::.::::..:::.::: :::::::.:::::::: :::::.:::::.:::: :::::
CCDS44 LRDYFEQYGKIEVIEIMTDRGSGKKRGFAFVTFDDHDSVDKIVIQKYHTVNGHNCEVRKA
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE3 LSRQEMQEDLEVAILEVAPVMEEEEEDMVVEDLDMATRVGATEVVMTTMEEEIMEVEITM
::.:::
CCDS44 LSKQEMASASSSQRGRSGSGNFGGGRGGGFGGNDNFGRGGNFSGRGGFGGSRGGGGYGGS
190 200 210 220 230 240
>>CCDS82536.1 HNRNPA3 gene_id:220988|Hs108|chr2 (356 aa)
initn: 996 init1: 996 opt: 996 Z-score: 980.1 bits: 189.4 E(32554): 2.8e-48
Smith-Waterman score: 996; 79.4% identity (94.4% similar) in 180 aa overlap (3-182:7-186)
10 20 30 40 50
pF1KE3 MEREKEQFRKLFIGGLSFETTEESLRNYYEQWGKLTDCVVMRDPASKRSRGFGFVT
.: ::.:::::::::::::..:::...:.:: :::::::::: .::::::::::
CCDS82 MEGHDPKEPEQLRKLFIGGLSFETTDDSLREHFEKWGTLTDCVVMRDPQTKRSRGFGFVT
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE3 FSSMAEVDAAMAARPHSIDGRVVEPKRAVAREESGKPGAHVTVKKLFVGGIKEDTEEHHL
.: . :::::: ::::..:::::::::::.::.: :::::.::::.:::::::::::..:
CCDS82 YSCVEEVDAAMCARPHKVDGRVVEPKRAVSREDSVKPGAHLTVKKIFVGGIKEDTEEYNL
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE3 RDYFEEYGKIDTIEIITDRQSGKKRGFGFVTFDDHDPVDKIVLQKYHTINGHNAEVRKAL
:::::.::::.:::.. ::::::::::.:::::::: :::::.:::::::::: ::.:::
CCDS82 RDYFEKYGKIETIEVMEDRQSGKKRGFAFVTFDDHDTVDKIVVQKYHTINGHNCEVKKAL
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE3 SRQEMQEDLEVAILEVAPVMEEEEEDMVVEDLDMATRVGATEVVMTTMEEEIMEVEITMI
:.::::
CCDS82 SKQEMQSAGSQRGRGGGSGNFMGRGGNFGGGGGNFGRGGNFGGRGGYGGGGGGSRGSYGG
190 200 210 220 230 240
>>CCDS2273.1 HNRNPA3 gene_id:220988|Hs108|chr2 (378 aa)
initn: 996 init1: 996 opt: 996 Z-score: 979.8 bits: 189.4 E(32554): 3e-48
Smith-Waterman score: 996; 79.4% identity (94.4% similar) in 180 aa overlap (3-182:29-208)
10 20 30
pF1KE3 MEREKEQFRKLFIGGLSFETTEESLRNYYEQWGK
.: ::.:::::::::::::..:::...:.::
CCDS22 MEVKPPPGRPQPDSGRRRRRRGEEGHDPKEPEQLRKLFIGGLSFETTDDSLREHFEKWGT
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE3 LTDCVVMRDPASKRSRGFGFVTFSSMAEVDAAMAARPHSIDGRVVEPKRAVAREESGKPG
:::::::::: .::::::::::.: . :::::: ::::..:::::::::::.::.: :::
CCDS22 LTDCVVMRDPQTKRSRGFGFVTYSCVEEVDAAMCARPHKVDGRVVEPKRAVSREDSVKPG
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE3 AHVTVKKLFVGGIKEDTEEHHLRDYFEEYGKIDTIEIITDRQSGKKRGFGFVTFDDHDPV
::.::::.:::::::::::..::::::.::::.:::.. ::::::::::.:::::::: :
CCDS22 AHLTVKKIFVGGIKEDTEEYNLRDYFEKYGKIETIEVMEDRQSGKKRGFAFVTFDDHDTV
130 140 150 160 170 180
160 170 180 190 200 210
pF1KE3 DKIVLQKYHTINGHNAEVRKALSRQEMQEDLEVAILEVAPVMEEEEEDMVVEDLDMATRV
::::.:::::::::: ::.::::.::::
CCDS22 DKIVVQKYHTINGHNCEVKKALSKQEMQSAGSQRGRGGGSGNFMGRGGNFGGGGGNFGRG
190 200 210 220 230 240
>>CCDS31980.1 HNRNPA1L2 gene_id:144983|Hs108|chr13 (320 aa)
initn: 986 init1: 986 opt: 986 Z-score: 971.0 bits: 187.5 E(32554): 9.1e-48
Smith-Waterman score: 986; 78.2% identity (93.9% similar) in 179 aa overlap (3-181:8-186)
10 20 30 40 50
pF1KE3 MEREKEQFRKLFIGGLSFETTEESLRNYYEQWGKLTDCVVMRDPASKRSRGFGFV
.: ::.:::::::::::::.::::...:::: :::::::::: .:::::::::
CCDS31 MSKSASPKEPEQLRKLFIGGLSFETTDESLRSHFEQWGTLTDCVVMRDPNTKRSRGFGFV
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE3 TFSSMAEVDAAMAARPHSIDGRVVEPKRAVAREESGKPGAHVTVKKLFVGGIKEDTEEHH
:.... :::::: . ::..:::::::::::.::.: .::::.::::.:::::::::::::
CCDS31 TYATVEEVDAAMNTTPHKVDGRVVEPKRAVSREDSQRPGAHLTVKKIFVGGIKEDTEEHH
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE3 LRDYFEEYGKIDTIEIITDRQSGKKRGFGFVTFDDHDPVDKIVLQKYHTINGHNAEVRKA
::::::.::::..:::.::: :::::::.:::::::: :::::.:::::..::: :::::
CCDS31 LRDYFEQYGKIEVIEIMTDRGSGKKRGFAFVTFDDHDSVDKIVIQKYHTVKGHNCEVRKA
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE3 LSRQEMQEDLEVAILEVAPVMEEEEEDMVVEDLDMATRVGATEVVMTTMEEEIMEVEITM
: .:::
CCDS31 LPKQEMASASSSQRGRRGSGNFGGGRGDGFGGNDNFGRGGNFSGRGGFGGSCGGGGYGGS
190 200 210 220 230 240
>>CCDS4193.1 HNRNPA0 gene_id:10949|Hs108|chr5 (305 aa)
initn: 865 init1: 683 opt: 692 Z-score: 686.5 bits: 134.8 E(32554): 6.4e-32
Smith-Waterman score: 692; 55.6% identity (83.1% similar) in 178 aa overlap (4-181:2-179)
10 20 30 40 50 60
pF1KE3 MEREKEQFRKLFIGGLSFETTEESLRNYYEQWGKLTDCVVMRDPASKRSRGFGFVTFSSM
:. :. :::::::. .:.: .::...: .: ::::::. .: .:::: :::::.:..
CCDS41 MENSQLCKLFIGGLNVQTSESGLRGHFEAFGTLTDCVVVVNPQTKRSRCFGFVTYSNV
10 20 30 40 50
70 80 90 100 110 120
pF1KE3 AEVDAAMAARPHSIDGRVVEPKRAVAREESGKPGAHVTVKKLFVGGIKEDTEEHHLRDYF
:.:::::: ::..:: .:: ::::.::.:..::::. ::::::::.: :. : : ..:
CCDS41 EEADAAMAASPHAVDGNTVELKRAVSREDSARPGAHAKVKKLFVGGLKGDVAEGDLIEHF
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE3 EEYGKIDTIEIITDRQSGKKRGFGFVTFDDHDPVDKIVLQKYHTINGHNAEVRKALSRQE
..: .. :::.:.::::::::::: :..:: .:: .. :.: :.:: .::.::. ...
CCDS41 SQFGTVEKAEIIADKQSGKKRGFGFVYFQNHDAADKAAVVKFHPIQGHRVEVKKAVPKED
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE3 MQEDLEVAILEVAPVMEEEEEDMVVEDLDMATRVGATEVVMTTMEEEIMEVEITMILEII
.
CCDS41 IYSGGGGGGSRSSRGGRGGRGRGGGRDQNGLSKGGGGGYNSYGGYGGGGGGGYNAYGGGG
180 190 200 210 220 230
>>CCDS9196.1 MSI1 gene_id:4440|Hs108|chr12 (362 aa)
initn: 555 init1: 304 opt: 528 Z-score: 526.6 bits: 105.5 E(32554): 5.2e-23
Smith-Waterman score: 528; 43.6% identity (77.9% similar) in 172 aa overlap (10-181:21-190)
10 20 30 40
pF1KE3 MEREKEQFRKLFIGGLSFETTEESLRNYYEQWGKLTDCVVMRDPASKRS
:.::::::..::.:.::.:. :.:.. .:.::::: .:::
CCDS91 METDAPQPGLASPDSPHDPCKMFIGGLSWQTTQEGLREYFGQFGEVKECLVMRDPLTKRS
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE3 RGFGFVTFSSMAEVDAAMAARPHSIDGRVVEPKRAVAREESGKPGAHVTVKKLFVGGIKE
:::::::: ..: :: ..: : .:.....:: : :. ..: . .::.::::..
CCDS91 RGFGFVTFMDQAGVDKVLAQSRHELDSKTIDPKVAFPRR--AQPKMVTRTKKIFVGGLSV
70 80 90 100 110
110 120 130 140 150 160
pF1KE3 DTEEHHLRDYFEEYGKIDTIEIITDRQSGKKRGFGFVTFDDHDPVDKIVLQKYHTINGHN
.: . ...:::..::.: .. :. ....::::::::...: :.:. ..: ::..
CCDS91 NTTVEDVKQYFEQFGKVDDAMLMFDKTTNRHRGFGFVTFESEDIVEKVCEIHFHEINNKM
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE3 AEVRKALSRQEMQEDLEVAILEVAPVMEEEEEDMVVEDLDMATRVGATEVVMTTMEEEIM
.: .:: .. :
CCDS91 VECKKAQPKEVMSPTGSARGRSRVMPYGMDAFMLGIGMLGYPGFQATTYASRSYTGLAPG
180 190 200 210 220 230
>>CCDS3591.1 HNRNPD gene_id:3184|Hs108|chr4 (336 aa)
initn: 489 init1: 264 opt: 527 Z-score: 526.1 bits: 105.3 E(32554): 5.5e-23
Smith-Waterman score: 527; 40.3% identity (77.9% similar) in 181 aa overlap (3-183:72-246)
10 20 30
pF1KE3 MEREKEQFRKLFIGGLSFETTEESLRNYYEQW
...:. :.::::::..::...:..:. ..
CCDS35 GSGAGTGGGTASGGTEGGSAESEGAKIDASKNEEDEGKMFIGGLSWDTTKKDLKDYFSKF
50 60 70 80 90 100
40 50 60 70 80 90
pF1KE3 GKLTDCVVMRDPASKRSRGFGFVTFSSMAEVDAAMAARPHSIDGRVVEPKRAVAREESGK
:...::.. :: . :::::::: :. :: .: . :...:.:..:::: : . . .
CCDS35 GEVVDCTLKLDPITGRSRGFGFVLFKESESVDKVMDQKEHKLNGKVIDPKRAKAMK-TKE
110 120 130 140 150 160
100 110 120 130 140 150
pF1KE3 PGAHVTVKKLFVGGIKEDTEEHHLRDYFEEYGKIDTIEIITDRQSGKKRGFGFVTFDDHD
: :::.::::.. :: :...:.:: .:....::. : ...:.::: :.:: ...
CCDS35 P-----VKKIFVGGLSPDTPEEKIREYFGGFGEVESIELPMDNKTNKRRGFCFITFKEEE
170 180 190 200 210
160 170 180 190 200 210
pF1KE3 PVDKIVLQKYHTINGHNAEVRKALSRQEMQEDLEVAILEVAPVMEEEEEDMVVEDLDMAT
:: ::. .:::... . :.. :.:....:.
CCDS35 PVKKIMEKKYHNVGLSKCEIKVAMSKEQYQQQQQWGSRGGFAGRARGRGGGPSQNWNQGY
220 230 240 250 260 270
220 230 240
pF1KE3 RVGATEVVMTTMEEEIMEVEITMILEIITSNLLTTVQ
CCDS35 SNYWNQGYGNYGYNSQGYGGYGGYDYTGYNNYYGYGDYSNQQSGYGKVSRRGGHQNSYKP
280 290 300 310 320 330
249 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 22:31:33 2016 done: Sat Nov 5 22:31:33 2016
Total Scan time: 1.980 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]