Result of FASTA (omim) for
pFN21AE3518
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3518, 691 aa
1>>>pF1KE3518 691 - 691 aa - 691 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.0205+/-0.000453; mu= 16.8949+/- 0.028
mean_var=101.3056+/-21.161, 0's: 0 Z-trim(112.1): 84 B-trim: 0 in 0/50
Lambda= 0.127426
statistics sampled from 20788 (20860) to 20788 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.606), E-opt: 0.2 (0.245), width: 16
Scan time: 11.060
The best scores are: opt bits E(85289)
NP_036293 (OMIM: 605655) F-box/LRR-repeat protein ( 691) 4691 873.8 0
NP_001180463 (OMIM: 605655) F-box/LRR-repeat prote ( 690) 4673 870.5 0
XP_006714022 (OMIM: 605655) PREDICTED: F-box/LRR-r ( 672) 4483 835.5 0
NP_001180464 (OMIM: 605655) F-box/LRR-repeat prote ( 674) 4378 816.2 0
XP_011512133 (OMIM: 605655) PREDICTED: F-box/LRR-r ( 655) 4376 815.8 0
XP_016863508 (OMIM: 605655) PREDICTED: F-box/LRR-r ( 636) 4321 805.7 0
XP_011512134 (OMIM: 605655) PREDICTED: F-box/LRR-r ( 636) 4321 805.7 0
XP_011512135 (OMIM: 605655) PREDICTED: F-box/LRR-r ( 619) 4048 755.5 1.3e-217
NP_001284366 (OMIM: 609090) F-box only protein 4 i ( 305) 174 43.1 0.0019
NP_277019 (OMIM: 609090) F-box only protein 4 isof ( 307) 174 43.1 0.0019
XP_011512328 (OMIM: 609090) PREDICTED: F-box only ( 341) 174 43.1 0.0021
NP_036308 (OMIM: 609090) F-box only protein 4 isof ( 387) 174 43.2 0.0023
NP_036289 (OMIM: 605652) F-box/LRR-repeat protein ( 423) 172 42.8 0.0032
XP_005265071 (OMIM: 605652) PREDICTED: F-box/LRR-r ( 454) 172 42.9 0.0033
XP_005257803 (OMIM: 609086) PREDICTED: F-box/LRR-r ( 473) 172 42.9 0.0034
NP_116264 (OMIM: 609086) F-box/LRR-repeat protein ( 436) 170 42.5 0.0042
NP_758954 (OMIM: 608519) F-box only protein 16 iso ( 292) 165 41.4 0.0058
>>NP_036293 (OMIM: 605655) F-box/LRR-repeat protein 5 is (691 aa)
initn: 4691 init1: 4691 opt: 4691 Z-score: 4665.8 bits: 873.8 E(85289): 0
Smith-Waterman score: 4691; 99.7% identity (99.7% similar) in 691 aa overlap (1-691:1-691)
10 20 30 40 50 60
pF1KE3 MAPFPEEVDVFTAPHWRMKQLVGLYCDKLSKTNFSNNNDFRALLQSLYATFTEFKMHEQI
::::::::::::::::::::::::::::::::::::::::::::::::::: ::::::::
NP_036 MAPFPEEVDVFTAPHWRMKQLVGLYCDKLSKTNFSNNNDFRALLQSLYATFKEFKMHEQI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 ENEYIIGLLQQRSQTIYNVHSDNKLSEMLSLFEKGLKNVKNEYEQLNYAKQLKERLEAFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 ENEYIIGLLQQRSQTIYNVHSDNKLSEMLSLFEKGLKNVKNEYEQLNYAKQLKERLEAFT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 RDFLPHMKEEEEVFQPMLMEYFTYEELKDIKKKVIAQHCSQKDTAELLRGLSLWNHAEER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 RDFLPHMKEEEEVFQPMLMEYFTYEELKDIKKKVIAQHCSQKDTAELLRGLSLWNHAEER
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 QKFFKYSVDEKSDKEAEVSEHSTGITHLPPEVMLSIFSYLNPQELCRCSQVSMKWSQLTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 QKFFKYSVDEKSDKEAEVSEHSTGITHLPPEVMLSIFSYLNPQELCRCSQVSMKWSQLTK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 TRSLWKHLYPVHWARGDWYSGPATELDTEPDDEWVKNRKDESRAFHEWDEDADIDESEES
: ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 TGSLWKHLYPVHWARGDWYSGPATELDTEPDDEWVKNRKDESRAFHEWDEDADIDESEES
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 AEESIAISIAQMEKRLLHGLIHNVLPYVGTSVKTLVLAYSSAVSSKMVRQILELCPNLEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 AEESIAISIAQMEKRLLHGLIHNVLPYVGTSVKTLVLAYSSAVSSKMVRQILELCPNLEH
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 LDLTQTDISDSAFDSWSWLGCCQSLRHLDLSGCEKITDVALEKISRALGILTSHQSGFLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 LDLTQTDISDSAFDSWSWLGCCQSLRHLDLSGCEKITDVALEKISRALGILTSHQSGFLK
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 TSTSKITSTAWKNKDITMQSTKQYACLHDLTNKGIGEEIDNEHPWTKPVSSENFTSPYVW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 TSTSKITSTAWKNKDITMQSTKQYACLHDLTNKGIGEEIDNEHPWTKPVSSENFTSPYVW
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 MLDAEDLADIEDTVEWRHRNVESLCVMETASNFSCSTSGCFSKDIVGLRTSVCWQQHCAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 MLDAEDLADIEDTVEWRHRNVESLCVMETASNFSCSTSGCFSKDIVGLRTSVCWQQHCAS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 PAFAYCGHSFCCTGTALRTMSSLPESSAMCRKAARTRLPRGKDLIYFGSEKSDQETGRVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 PAFAYCGHSFCCTGTALRTMSSLPESSAMCRKAARTRLPRGKDLIYFGSEKSDQETGRVL
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 LFLSLSGCYQITDHGLRVLTLGGGLPYLEHLNLSGCLTITGAGLQDLVSACPSLNDEYFY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 LFLSLSGCYQITDHGLRVLTLGGGLPYLEHLNLSGCLTITGAGLQDLVSACPSLNDEYFY
610 620 630 640 650 660
670 680 690
pF1KE3 YCDNINGPHADTASGCQNLQCGFRACCRSGE
:::::::::::::::::::::::::::::::
NP_036 YCDNINGPHADTASGCQNLQCGFRACCRSGE
670 680 690
>>NP_001180463 (OMIM: 605655) F-box/LRR-repeat protein 5 (690 aa)
initn: 3411 init1: 3411 opt: 4673 Z-score: 4647.9 bits: 870.5 E(85289): 0
Smith-Waterman score: 4673; 99.6% identity (99.6% similar) in 691 aa overlap (1-691:1-690)
10 20 30 40 50 60
pF1KE3 MAPFPEEVDVFTAPHWRMKQLVGLYCDKLSKTNFSNNNDFRALLQSLYATFTEFKMHEQI
::::::::::::::::::::::::::::::::::::::::::::::::::: ::::::::
NP_001 MAPFPEEVDVFTAPHWRMKQLVGLYCDKLSKTNFSNNNDFRALLQSLYATFKEFKMHEQI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 ENEYIIGLLQQRSQTIYNVHSDNKLSEMLSLFEKGLKNVKNEYEQLNYAKQLKERLEAFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ENEYIIGLLQQRSQTIYNVHSDNKLSEMLSLFEKGLKNVKNEYEQLNYAKQLKERLEAFT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 RDFLPHMKEEEEVFQPMLMEYFTYEELKDIKKKVIAQHCSQKDTAELLRGLSLWNHAEER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RDFLPHMKEEEEVFQPMLMEYFTYEELKDIKKKVIAQHCSQKDTAELLRGLSLWNHAEER
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 QKFFKYSVDEKSDKEAEVSEHSTGITHLPPEVMLSIFSYLNPQELCRCSQVSMKWSQLTK
:::::::::::::: :::::::::::::::::::::::::::::::::::::::::::::
NP_001 QKFFKYSVDEKSDK-AEVSEHSTGITHLPPEVMLSIFSYLNPQELCRCSQVSMKWSQLTK
190 200 210 220 230
250 260 270 280 290 300
pF1KE3 TRSLWKHLYPVHWARGDWYSGPATELDTEPDDEWVKNRKDESRAFHEWDEDADIDESEES
: ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TGSLWKHLYPVHWARGDWYSGPATELDTEPDDEWVKNRKDESRAFHEWDEDADIDESEES
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE3 AEESIAISIAQMEKRLLHGLIHNVLPYVGTSVKTLVLAYSSAVSSKMVRQILELCPNLEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AEESIAISIAQMEKRLLHGLIHNVLPYVGTSVKTLVLAYSSAVSSKMVRQILELCPNLEH
300 310 320 330 340 350
370 380 390 400 410 420
pF1KE3 LDLTQTDISDSAFDSWSWLGCCQSLRHLDLSGCEKITDVALEKISRALGILTSHQSGFLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LDLTQTDISDSAFDSWSWLGCCQSLRHLDLSGCEKITDVALEKISRALGILTSHQSGFLK
360 370 380 390 400 410
430 440 450 460 470 480
pF1KE3 TSTSKITSTAWKNKDITMQSTKQYACLHDLTNKGIGEEIDNEHPWTKPVSSENFTSPYVW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TSTSKITSTAWKNKDITMQSTKQYACLHDLTNKGIGEEIDNEHPWTKPVSSENFTSPYVW
420 430 440 450 460 470
490 500 510 520 530 540
pF1KE3 MLDAEDLADIEDTVEWRHRNVESLCVMETASNFSCSTSGCFSKDIVGLRTSVCWQQHCAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MLDAEDLADIEDTVEWRHRNVESLCVMETASNFSCSTSGCFSKDIVGLRTSVCWQQHCAS
480 490 500 510 520 530
550 560 570 580 590 600
pF1KE3 PAFAYCGHSFCCTGTALRTMSSLPESSAMCRKAARTRLPRGKDLIYFGSEKSDQETGRVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PAFAYCGHSFCCTGTALRTMSSLPESSAMCRKAARTRLPRGKDLIYFGSEKSDQETGRVL
540 550 560 570 580 590
610 620 630 640 650 660
pF1KE3 LFLSLSGCYQITDHGLRVLTLGGGLPYLEHLNLSGCLTITGAGLQDLVSACPSLNDEYFY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LFLSLSGCYQITDHGLRVLTLGGGLPYLEHLNLSGCLTITGAGLQDLVSACPSLNDEYFY
600 610 620 630 640 650
670 680 690
pF1KE3 YCDNINGPHADTASGCQNLQCGFRACCRSGE
:::::::::::::::::::::::::::::::
NP_001 YCDNINGPHADTASGCQNLQCGFRACCRSGE
660 670 680 690
>>XP_006714022 (OMIM: 605655) PREDICTED: F-box/LRR-repea (672 aa)
initn: 4483 init1: 4483 opt: 4483 Z-score: 4459.3 bits: 835.5 E(85289): 0
Smith-Waterman score: 4483; 99.7% identity (99.7% similar) in 663 aa overlap (29-691:10-672)
10 20 30 40 50 60
pF1KE3 MAPFPEEVDVFTAPHWRMKQLVGLYCDKLSKTNFSNNNDFRALLQSLYATFTEFKMHEQI
::::::::::::::::::::::: ::::::::
XP_006 MGKRQTFSWLSKTNFSNNNDFRALLQSLYATFKEFKMHEQI
10 20 30 40
70 80 90 100 110 120
pF1KE3 ENEYIIGLLQQRSQTIYNVHSDNKLSEMLSLFEKGLKNVKNEYEQLNYAKQLKERLEAFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ENEYIIGLLQQRSQTIYNVHSDNKLSEMLSLFEKGLKNVKNEYEQLNYAKQLKERLEAFT
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE3 RDFLPHMKEEEEVFQPMLMEYFTYEELKDIKKKVIAQHCSQKDTAELLRGLSLWNHAEER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RDFLPHMKEEEEVFQPMLMEYFTYEELKDIKKKVIAQHCSQKDTAELLRGLSLWNHAEER
110 120 130 140 150 160
190 200 210 220 230 240
pF1KE3 QKFFKYSVDEKSDKEAEVSEHSTGITHLPPEVMLSIFSYLNPQELCRCSQVSMKWSQLTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QKFFKYSVDEKSDKEAEVSEHSTGITHLPPEVMLSIFSYLNPQELCRCSQVSMKWSQLTK
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE3 TRSLWKHLYPVHWARGDWYSGPATELDTEPDDEWVKNRKDESRAFHEWDEDADIDESEES
: ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TGSLWKHLYPVHWARGDWYSGPATELDTEPDDEWVKNRKDESRAFHEWDEDADIDESEES
230 240 250 260 270 280
310 320 330 340 350 360
pF1KE3 AEESIAISIAQMEKRLLHGLIHNVLPYVGTSVKTLVLAYSSAVSSKMVRQILELCPNLEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AEESIAISIAQMEKRLLHGLIHNVLPYVGTSVKTLVLAYSSAVSSKMVRQILELCPNLEH
290 300 310 320 330 340
370 380 390 400 410 420
pF1KE3 LDLTQTDISDSAFDSWSWLGCCQSLRHLDLSGCEKITDVALEKISRALGILTSHQSGFLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LDLTQTDISDSAFDSWSWLGCCQSLRHLDLSGCEKITDVALEKISRALGILTSHQSGFLK
350 360 370 380 390 400
430 440 450 460 470 480
pF1KE3 TSTSKITSTAWKNKDITMQSTKQYACLHDLTNKGIGEEIDNEHPWTKPVSSENFTSPYVW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TSTSKITSTAWKNKDITMQSTKQYACLHDLTNKGIGEEIDNEHPWTKPVSSENFTSPYVW
410 420 430 440 450 460
490 500 510 520 530 540
pF1KE3 MLDAEDLADIEDTVEWRHRNVESLCVMETASNFSCSTSGCFSKDIVGLRTSVCWQQHCAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MLDAEDLADIEDTVEWRHRNVESLCVMETASNFSCSTSGCFSKDIVGLRTSVCWQQHCAS
470 480 490 500 510 520
550 560 570 580 590 600
pF1KE3 PAFAYCGHSFCCTGTALRTMSSLPESSAMCRKAARTRLPRGKDLIYFGSEKSDQETGRVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PAFAYCGHSFCCTGTALRTMSSLPESSAMCRKAARTRLPRGKDLIYFGSEKSDQETGRVL
530 540 550 560 570 580
610 620 630 640 650 660
pF1KE3 LFLSLSGCYQITDHGLRVLTLGGGLPYLEHLNLSGCLTITGAGLQDLVSACPSLNDEYFY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LFLSLSGCYQITDHGLRVLTLGGGLPYLEHLNLSGCLTITGAGLQDLVSACPSLNDEYFY
590 600 610 620 630 640
670 680 690
pF1KE3 YCDNINGPHADTASGCQNLQCGFRACCRSGE
:::::::::::::::::::::::::::::::
XP_006 YCDNINGPHADTASGCQNLQCGFRACCRSGE
650 660 670
>>NP_001180464 (OMIM: 605655) F-box/LRR-repeat protein 5 (674 aa)
initn: 4378 init1: 4378 opt: 4378 Z-score: 4354.9 bits: 816.2 E(85289): 0
Smith-Waterman score: 4540; 97.3% identity (97.3% similar) in 691 aa overlap (1-691:1-674)
10 20 30 40 50 60
pF1KE3 MAPFPEEVDVFTAPHWRMKQLVGLYCDKLSKTNFSNNNDFRALLQSLYATFTEFKMHEQI
:::::::::::::::::::::::::::: :::::: ::::::::
NP_001 MAPFPEEVDVFTAPHWRMKQLVGLYCDK-----------------SLYATFKEFKMHEQI
10 20 30 40
70 80 90 100 110 120
pF1KE3 ENEYIIGLLQQRSQTIYNVHSDNKLSEMLSLFEKGLKNVKNEYEQLNYAKQLKERLEAFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ENEYIIGLLQQRSQTIYNVHSDNKLSEMLSLFEKGLKNVKNEYEQLNYAKQLKERLEAFT
50 60 70 80 90 100
130 140 150 160 170 180
pF1KE3 RDFLPHMKEEEEVFQPMLMEYFTYEELKDIKKKVIAQHCSQKDTAELLRGLSLWNHAEER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RDFLPHMKEEEEVFQPMLMEYFTYEELKDIKKKVIAQHCSQKDTAELLRGLSLWNHAEER
110 120 130 140 150 160
190 200 210 220 230 240
pF1KE3 QKFFKYSVDEKSDKEAEVSEHSTGITHLPPEVMLSIFSYLNPQELCRCSQVSMKWSQLTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QKFFKYSVDEKSDKEAEVSEHSTGITHLPPEVMLSIFSYLNPQELCRCSQVSMKWSQLTK
170 180 190 200 210 220
250 260 270 280 290 300
pF1KE3 TRSLWKHLYPVHWARGDWYSGPATELDTEPDDEWVKNRKDESRAFHEWDEDADIDESEES
: ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TGSLWKHLYPVHWARGDWYSGPATELDTEPDDEWVKNRKDESRAFHEWDEDADIDESEES
230 240 250 260 270 280
310 320 330 340 350 360
pF1KE3 AEESIAISIAQMEKRLLHGLIHNVLPYVGTSVKTLVLAYSSAVSSKMVRQILELCPNLEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AEESIAISIAQMEKRLLHGLIHNVLPYVGTSVKTLVLAYSSAVSSKMVRQILELCPNLEH
290 300 310 320 330 340
370 380 390 400 410 420
pF1KE3 LDLTQTDISDSAFDSWSWLGCCQSLRHLDLSGCEKITDVALEKISRALGILTSHQSGFLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LDLTQTDISDSAFDSWSWLGCCQSLRHLDLSGCEKITDVALEKISRALGILTSHQSGFLK
350 360 370 380 390 400
430 440 450 460 470 480
pF1KE3 TSTSKITSTAWKNKDITMQSTKQYACLHDLTNKGIGEEIDNEHPWTKPVSSENFTSPYVW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TSTSKITSTAWKNKDITMQSTKQYACLHDLTNKGIGEEIDNEHPWTKPVSSENFTSPYVW
410 420 430 440 450 460
490 500 510 520 530 540
pF1KE3 MLDAEDLADIEDTVEWRHRNVESLCVMETASNFSCSTSGCFSKDIVGLRTSVCWQQHCAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MLDAEDLADIEDTVEWRHRNVESLCVMETASNFSCSTSGCFSKDIVGLRTSVCWQQHCAS
470 480 490 500 510 520
550 560 570 580 590 600
pF1KE3 PAFAYCGHSFCCTGTALRTMSSLPESSAMCRKAARTRLPRGKDLIYFGSEKSDQETGRVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PAFAYCGHSFCCTGTALRTMSSLPESSAMCRKAARTRLPRGKDLIYFGSEKSDQETGRVL
530 540 550 560 570 580
610 620 630 640 650 660
pF1KE3 LFLSLSGCYQITDHGLRVLTLGGGLPYLEHLNLSGCLTITGAGLQDLVSACPSLNDEYFY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LFLSLSGCYQITDHGLRVLTLGGGLPYLEHLNLSGCLTITGAGLQDLVSACPSLNDEYFY
590 600 610 620 630 640
670 680 690
pF1KE3 YCDNINGPHADTASGCQNLQCGFRACCRSGE
:::::::::::::::::::::::::::::::
NP_001 YCDNINGPHADTASGCQNLQCGFRACCRSGE
650 660 670
>>XP_011512133 (OMIM: 605655) PREDICTED: F-box/LRR-repea (655 aa)
initn: 4376 init1: 4376 opt: 4376 Z-score: 4353.1 bits: 815.8 E(85289): 0
Smith-Waterman score: 4376; 99.7% identity (99.7% similar) in 646 aa overlap (46-691:10-655)
20 30 40 50 60 70
pF1KE3 WRMKQLVGLYCDKLSKTNFSNNNDFRALLQSLYATFTEFKMHEQIENEYIIGLLQQRSQT
:::::: :::::::::::::::::::::::
XP_011 MGKRQTFSWSLYATFKEFKMHEQIENEYIIGLLQQRSQT
10 20 30
80 90 100 110 120 130
pF1KE3 IYNVHSDNKLSEMLSLFEKGLKNVKNEYEQLNYAKQLKERLEAFTRDFLPHMKEEEEVFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IYNVHSDNKLSEMLSLFEKGLKNVKNEYEQLNYAKQLKERLEAFTRDFLPHMKEEEEVFQ
40 50 60 70 80 90
140 150 160 170 180 190
pF1KE3 PMLMEYFTYEELKDIKKKVIAQHCSQKDTAELLRGLSLWNHAEERQKFFKYSVDEKSDKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PMLMEYFTYEELKDIKKKVIAQHCSQKDTAELLRGLSLWNHAEERQKFFKYSVDEKSDKE
100 110 120 130 140 150
200 210 220 230 240 250
pF1KE3 AEVSEHSTGITHLPPEVMLSIFSYLNPQELCRCSQVSMKWSQLTKTRSLWKHLYPVHWAR
:::::::::::::::::::::::::::::::::::::::::::::: :::::::::::::
XP_011 AEVSEHSTGITHLPPEVMLSIFSYLNPQELCRCSQVSMKWSQLTKTGSLWKHLYPVHWAR
160 170 180 190 200 210
260 270 280 290 300 310
pF1KE3 GDWYSGPATELDTEPDDEWVKNRKDESRAFHEWDEDADIDESEESAEESIAISIAQMEKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GDWYSGPATELDTEPDDEWVKNRKDESRAFHEWDEDADIDESEESAEESIAISIAQMEKR
220 230 240 250 260 270
320 330 340 350 360 370
pF1KE3 LLHGLIHNVLPYVGTSVKTLVLAYSSAVSSKMVRQILELCPNLEHLDLTQTDISDSAFDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLHGLIHNVLPYVGTSVKTLVLAYSSAVSSKMVRQILELCPNLEHLDLTQTDISDSAFDS
280 290 300 310 320 330
380 390 400 410 420 430
pF1KE3 WSWLGCCQSLRHLDLSGCEKITDVALEKISRALGILTSHQSGFLKTSTSKITSTAWKNKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WSWLGCCQSLRHLDLSGCEKITDVALEKISRALGILTSHQSGFLKTSTSKITSTAWKNKD
340 350 360 370 380 390
440 450 460 470 480 490
pF1KE3 ITMQSTKQYACLHDLTNKGIGEEIDNEHPWTKPVSSENFTSPYVWMLDAEDLADIEDTVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ITMQSTKQYACLHDLTNKGIGEEIDNEHPWTKPVSSENFTSPYVWMLDAEDLADIEDTVE
400 410 420 430 440 450
500 510 520 530 540 550
pF1KE3 WRHRNVESLCVMETASNFSCSTSGCFSKDIVGLRTSVCWQQHCASPAFAYCGHSFCCTGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WRHRNVESLCVMETASNFSCSTSGCFSKDIVGLRTSVCWQQHCASPAFAYCGHSFCCTGT
460 470 480 490 500 510
560 570 580 590 600 610
pF1KE3 ALRTMSSLPESSAMCRKAARTRLPRGKDLIYFGSEKSDQETGRVLLFLSLSGCYQITDHG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALRTMSSLPESSAMCRKAARTRLPRGKDLIYFGSEKSDQETGRVLLFLSLSGCYQITDHG
520 530 540 550 560 570
620 630 640 650 660 670
pF1KE3 LRVLTLGGGLPYLEHLNLSGCLTITGAGLQDLVSACPSLNDEYFYYCDNINGPHADTASG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRVLTLGGGLPYLEHLNLSGCLTITGAGLQDLVSACPSLNDEYFYYCDNINGPHADTASG
580 590 600 610 620 630
680 690
pF1KE3 CQNLQCGFRACCRSGE
::::::::::::::::
XP_011 CQNLQCGFRACCRSGE
640 650
>>XP_016863508 (OMIM: 605655) PREDICTED: F-box/LRR-repea (636 aa)
initn: 4321 init1: 4321 opt: 4321 Z-score: 4298.6 bits: 805.7 E(85289): 0
Smith-Waterman score: 4321; 99.8% identity (99.8% similar) in 636 aa overlap (56-691:1-636)
30 40 50 60 70 80
pF1KE3 CDKLSKTNFSNNNDFRALLQSLYATFTEFKMHEQIENEYIIGLLQQRSQTIYNVHSDNKL
::::::::::::::::::::::::::::::
XP_016 MHEQIENEYIIGLLQQRSQTIYNVHSDNKL
10 20 30
90 100 110 120 130 140
pF1KE3 SEMLSLFEKGLKNVKNEYEQLNYAKQLKERLEAFTRDFLPHMKEEEEVFQPMLMEYFTYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SEMLSLFEKGLKNVKNEYEQLNYAKQLKERLEAFTRDFLPHMKEEEEVFQPMLMEYFTYE
40 50 60 70 80 90
150 160 170 180 190 200
pF1KE3 ELKDIKKKVIAQHCSQKDTAELLRGLSLWNHAEERQKFFKYSVDEKSDKEAEVSEHSTGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELKDIKKKVIAQHCSQKDTAELLRGLSLWNHAEERQKFFKYSVDEKSDKEAEVSEHSTGI
100 110 120 130 140 150
210 220 230 240 250 260
pF1KE3 THLPPEVMLSIFSYLNPQELCRCSQVSMKWSQLTKTRSLWKHLYPVHWARGDWYSGPATE
:::::::::::::::::::::::::::::::::::: :::::::::::::::::::::::
XP_016 THLPPEVMLSIFSYLNPQELCRCSQVSMKWSQLTKTGSLWKHLYPVHWARGDWYSGPATE
160 170 180 190 200 210
270 280 290 300 310 320
pF1KE3 LDTEPDDEWVKNRKDESRAFHEWDEDADIDESEESAEESIAISIAQMEKRLLHGLIHNVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LDTEPDDEWVKNRKDESRAFHEWDEDADIDESEESAEESIAISIAQMEKRLLHGLIHNVL
220 230 240 250 260 270
330 340 350 360 370 380
pF1KE3 PYVGTSVKTLVLAYSSAVSSKMVRQILELCPNLEHLDLTQTDISDSAFDSWSWLGCCQSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PYVGTSVKTLVLAYSSAVSSKMVRQILELCPNLEHLDLTQTDISDSAFDSWSWLGCCQSL
280 290 300 310 320 330
390 400 410 420 430 440
pF1KE3 RHLDLSGCEKITDVALEKISRALGILTSHQSGFLKTSTSKITSTAWKNKDITMQSTKQYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RHLDLSGCEKITDVALEKISRALGILTSHQSGFLKTSTSKITSTAWKNKDITMQSTKQYA
340 350 360 370 380 390
450 460 470 480 490 500
pF1KE3 CLHDLTNKGIGEEIDNEHPWTKPVSSENFTSPYVWMLDAEDLADIEDTVEWRHRNVESLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CLHDLTNKGIGEEIDNEHPWTKPVSSENFTSPYVWMLDAEDLADIEDTVEWRHRNVESLC
400 410 420 430 440 450
510 520 530 540 550 560
pF1KE3 VMETASNFSCSTSGCFSKDIVGLRTSVCWQQHCASPAFAYCGHSFCCTGTALRTMSSLPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VMETASNFSCSTSGCFSKDIVGLRTSVCWQQHCASPAFAYCGHSFCCTGTALRTMSSLPE
460 470 480 490 500 510
570 580 590 600 610 620
pF1KE3 SSAMCRKAARTRLPRGKDLIYFGSEKSDQETGRVLLFLSLSGCYQITDHGLRVLTLGGGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSAMCRKAARTRLPRGKDLIYFGSEKSDQETGRVLLFLSLSGCYQITDHGLRVLTLGGGL
520 530 540 550 560 570
630 640 650 660 670 680
pF1KE3 PYLEHLNLSGCLTITGAGLQDLVSACPSLNDEYFYYCDNINGPHADTASGCQNLQCGFRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PYLEHLNLSGCLTITGAGLQDLVSACPSLNDEYFYYCDNINGPHADTASGCQNLQCGFRA
580 590 600 610 620 630
690
pF1KE3 CCRSGE
::::::
XP_016 CCRSGE
>>XP_011512134 (OMIM: 605655) PREDICTED: F-box/LRR-repea (636 aa)
initn: 4321 init1: 4321 opt: 4321 Z-score: 4298.6 bits: 805.7 E(85289): 0
Smith-Waterman score: 4321; 99.8% identity (99.8% similar) in 636 aa overlap (56-691:1-636)
30 40 50 60 70 80
pF1KE3 CDKLSKTNFSNNNDFRALLQSLYATFTEFKMHEQIENEYIIGLLQQRSQTIYNVHSDNKL
::::::::::::::::::::::::::::::
XP_011 MHEQIENEYIIGLLQQRSQTIYNVHSDNKL
10 20 30
90 100 110 120 130 140
pF1KE3 SEMLSLFEKGLKNVKNEYEQLNYAKQLKERLEAFTRDFLPHMKEEEEVFQPMLMEYFTYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SEMLSLFEKGLKNVKNEYEQLNYAKQLKERLEAFTRDFLPHMKEEEEVFQPMLMEYFTYE
40 50 60 70 80 90
150 160 170 180 190 200
pF1KE3 ELKDIKKKVIAQHCSQKDTAELLRGLSLWNHAEERQKFFKYSVDEKSDKEAEVSEHSTGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELKDIKKKVIAQHCSQKDTAELLRGLSLWNHAEERQKFFKYSVDEKSDKEAEVSEHSTGI
100 110 120 130 140 150
210 220 230 240 250 260
pF1KE3 THLPPEVMLSIFSYLNPQELCRCSQVSMKWSQLTKTRSLWKHLYPVHWARGDWYSGPATE
:::::::::::::::::::::::::::::::::::: :::::::::::::::::::::::
XP_011 THLPPEVMLSIFSYLNPQELCRCSQVSMKWSQLTKTGSLWKHLYPVHWARGDWYSGPATE
160 170 180 190 200 210
270 280 290 300 310 320
pF1KE3 LDTEPDDEWVKNRKDESRAFHEWDEDADIDESEESAEESIAISIAQMEKRLLHGLIHNVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LDTEPDDEWVKNRKDESRAFHEWDEDADIDESEESAEESIAISIAQMEKRLLHGLIHNVL
220 230 240 250 260 270
330 340 350 360 370 380
pF1KE3 PYVGTSVKTLVLAYSSAVSSKMVRQILELCPNLEHLDLTQTDISDSAFDSWSWLGCCQSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PYVGTSVKTLVLAYSSAVSSKMVRQILELCPNLEHLDLTQTDISDSAFDSWSWLGCCQSL
280 290 300 310 320 330
390 400 410 420 430 440
pF1KE3 RHLDLSGCEKITDVALEKISRALGILTSHQSGFLKTSTSKITSTAWKNKDITMQSTKQYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RHLDLSGCEKITDVALEKISRALGILTSHQSGFLKTSTSKITSTAWKNKDITMQSTKQYA
340 350 360 370 380 390
450 460 470 480 490 500
pF1KE3 CLHDLTNKGIGEEIDNEHPWTKPVSSENFTSPYVWMLDAEDLADIEDTVEWRHRNVESLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CLHDLTNKGIGEEIDNEHPWTKPVSSENFTSPYVWMLDAEDLADIEDTVEWRHRNVESLC
400 410 420 430 440 450
510 520 530 540 550 560
pF1KE3 VMETASNFSCSTSGCFSKDIVGLRTSVCWQQHCASPAFAYCGHSFCCTGTALRTMSSLPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VMETASNFSCSTSGCFSKDIVGLRTSVCWQQHCASPAFAYCGHSFCCTGTALRTMSSLPE
460 470 480 490 500 510
570 580 590 600 610 620
pF1KE3 SSAMCRKAARTRLPRGKDLIYFGSEKSDQETGRVLLFLSLSGCYQITDHGLRVLTLGGGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSAMCRKAARTRLPRGKDLIYFGSEKSDQETGRVLLFLSLSGCYQITDHGLRVLTLGGGL
520 530 540 550 560 570
630 640 650 660 670 680
pF1KE3 PYLEHLNLSGCLTITGAGLQDLVSACPSLNDEYFYYCDNINGPHADTASGCQNLQCGFRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PYLEHLNLSGCLTITGAGLQDLVSACPSLNDEYFYYCDNINGPHADTASGCQNLQCGFRA
580 590 600 610 620 630
690
pF1KE3 CCRSGE
::::::
XP_011 CCRSGE
>>XP_011512135 (OMIM: 605655) PREDICTED: F-box/LRR-repea (619 aa)
initn: 4048 init1: 4048 opt: 4048 Z-score: 4027.6 bits: 755.5 E(85289): 1.3e-217
Smith-Waterman score: 4091; 89.4% identity (89.4% similar) in 691 aa overlap (1-691:1-619)
10 20 30 40 50 60
pF1KE3 MAPFPEEVDVFTAPHWRMKQLVGLYCDKLSKTNFSNNNDFRALLQSLYATFTEFKMHEQI
::::::::::::::::::::::::::::
XP_011 MAPFPEEVDVFTAPHWRMKQLVGLYCDK--------------------------------
10 20
70 80 90 100 110 120
pF1KE3 ENEYIIGLLQQRSQTIYNVHSDNKLSEMLSLFEKGLKNVKNEYEQLNYAKQLKERLEAFT
::::::::::::::::::::
XP_011 ----------------------------------------NEYEQLNYAKQLKERLEAFT
30 40
130 140 150 160 170 180
pF1KE3 RDFLPHMKEEEEVFQPMLMEYFTYEELKDIKKKVIAQHCSQKDTAELLRGLSLWNHAEER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RDFLPHMKEEEEVFQPMLMEYFTYEELKDIKKKVIAQHCSQKDTAELLRGLSLWNHAEER
50 60 70 80 90 100
190 200 210 220 230 240
pF1KE3 QKFFKYSVDEKSDKEAEVSEHSTGITHLPPEVMLSIFSYLNPQELCRCSQVSMKWSQLTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QKFFKYSVDEKSDKEAEVSEHSTGITHLPPEVMLSIFSYLNPQELCRCSQVSMKWSQLTK
110 120 130 140 150 160
250 260 270 280 290 300
pF1KE3 TRSLWKHLYPVHWARGDWYSGPATELDTEPDDEWVKNRKDESRAFHEWDEDADIDESEES
: ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TGSLWKHLYPVHWARGDWYSGPATELDTEPDDEWVKNRKDESRAFHEWDEDADIDESEES
170 180 190 200 210 220
310 320 330 340 350 360
pF1KE3 AEESIAISIAQMEKRLLHGLIHNVLPYVGTSVKTLVLAYSSAVSSKMVRQILELCPNLEH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AEESIAISIAQMEKRLLHGLIHNVLPYVGTSVKTLVLAYSSAVSSKMVRQILELCPNLEH
230 240 250 260 270 280
370 380 390 400 410 420
pF1KE3 LDLTQTDISDSAFDSWSWLGCCQSLRHLDLSGCEKITDVALEKISRALGILTSHQSGFLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LDLTQTDISDSAFDSWSWLGCCQSLRHLDLSGCEKITDVALEKISRALGILTSHQSGFLK
290 300 310 320 330 340
430 440 450 460 470 480
pF1KE3 TSTSKITSTAWKNKDITMQSTKQYACLHDLTNKGIGEEIDNEHPWTKPVSSENFTSPYVW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TSTSKITSTAWKNKDITMQSTKQYACLHDLTNKGIGEEIDNEHPWTKPVSSENFTSPYVW
350 360 370 380 390 400
490 500 510 520 530 540
pF1KE3 MLDAEDLADIEDTVEWRHRNVESLCVMETASNFSCSTSGCFSKDIVGLRTSVCWQQHCAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MLDAEDLADIEDTVEWRHRNVESLCVMETASNFSCSTSGCFSKDIVGLRTSVCWQQHCAS
410 420 430 440 450 460
550 560 570 580 590 600
pF1KE3 PAFAYCGHSFCCTGTALRTMSSLPESSAMCRKAARTRLPRGKDLIYFGSEKSDQETGRVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PAFAYCGHSFCCTGTALRTMSSLPESSAMCRKAARTRLPRGKDLIYFGSEKSDQETGRVL
470 480 490 500 510 520
610 620 630 640 650 660
pF1KE3 LFLSLSGCYQITDHGLRVLTLGGGLPYLEHLNLSGCLTITGAGLQDLVSACPSLNDEYFY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LFLSLSGCYQITDHGLRVLTLGGGLPYLEHLNLSGCLTITGAGLQDLVSACPSLNDEYFY
530 540 550 560 570 580
670 680 690
pF1KE3 YCDNINGPHADTASGCQNLQCGFRACCRSGE
:::::::::::::::::::::::::::::::
XP_011 YCDNINGPHADTASGCQNLQCGFRACCRSGE
590 600 610
>>NP_001284366 (OMIM: 609090) F-box only protein 4 isofo (305 aa)
initn: 159 init1: 133 opt: 174 Z-score: 182.9 bits: 43.1 E(85289): 0.0019
Smith-Waterman score: 174; 30.9% identity (64.9% similar) in 97 aa overlap (181-273:36-130)
160 170 180 190 200 210
pF1KE3 KKKVIAQHCSQKDTAELLRGLSLWNHAEERQKFFKYSVDEKSDKEAEVSEHSTGITHLPP
:. : : . ...: ::.: .. .:.::
NP_001 PRSGTNSPPPPFSDWGRLEAAILSGWKTFWQSVSKERVARTTSRE-EVDEAASTLTRLPI
10 20 30 40 50 60
220 230 240 250 260
pF1KE3 EVMLSIFSYLNPQELCRCSQVSMKWSQLTKTRSLWKHLY----PVHWARGDWYSGPATEL
.:.: :.:.:.:..::. .... :.. .. ::... : :. :: : : :.
NP_001 DVQLYILSFLSPHDLCQLGSTNHYWNETVRDPILWRYFLLRDLP-SWSSVDWKSLPDLEI
70 80 90 100 110 120
270 280 290 300 310 320
pF1KE3 DTEPDDEWVKNRKDESRAFHEWDEDADIDESEESAEESIAISIAQMEKRLLHGLIHNVLP
.: .:
NP_001 LKKPISEVTDGAFFDYMAVYRMCCPYTRRASKSSRPMYGAVTSFLHSLIIQNEPRFAMFG
130 140 150 160 170 180
>>NP_277019 (OMIM: 609090) F-box only protein 4 isoform (307 aa)
initn: 159 init1: 133 opt: 174 Z-score: 182.8 bits: 43.1 E(85289): 0.0019
Smith-Waterman score: 174; 30.9% identity (64.9% similar) in 97 aa overlap (181-273:36-130)
160 170 180 190 200 210
pF1KE3 KKKVIAQHCSQKDTAELLRGLSLWNHAEERQKFFKYSVDEKSDKEAEVSEHSTGITHLPP
:. : : . ...: ::.: .. .:.::
NP_277 PRSGTNSPPPPFSDWGRLEAAILSGWKTFWQSVSKERVARTTSRE-EVDEAASTLTRLPI
10 20 30 40 50 60
220 230 240 250 260
pF1KE3 EVMLSIFSYLNPQELCRCSQVSMKWSQLTKTRSLWKHLY----PVHWARGDWYSGPATEL
.:.: :.:.:.:..::. .... :.. .. ::... : :. :: : : :.
NP_277 DVQLYILSFLSPHDLCQLGSTNHYWNETVRDPILWRYFLLRDLP-SWSSVDWKSLPDLEI
70 80 90 100 110 120
270 280 290 300 310 320
pF1KE3 DTEPDDEWVKNRKDESRAFHEWDEDADIDESEESAEESIAISIAQMEKRLLHGLIHNVLP
.: .:
NP_277 LKKPISEVTDGAFFDYMAVYRMCCPYTRRASKSSRPMYGAVTSFLHSLIIQNEPRFAMFG
130 140 150 160 170 180
691 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 22:28:49 2016 done: Sun Nov 6 22:28:50 2016
Total Scan time: 11.060 Total Display time: 0.150
Function used was FASTA [36.3.4 Apr, 2011]