Result of FASTA (omim) for
pFN21AE3492
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3492, 1843 aa
1>>>pF1KE3492 1843 - 1843 aa - 1843 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 19.8733+/-0.00079; mu= -48.0468+/- 0.049
mean_var=838.6366+/-173.080, 0's: 0 Z-trim(115.2): 684 B-trim: 0 in 0/56
Lambda= 0.044288
statistics sampled from 24754 (25433) to 24754 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.592), E-opt: 0.2 (0.298), width: 16
Scan time: 21.910
The best scores are: opt bits E(85289)
NP_060554 (OMIM: 260565,609736) girdin isoform 2 [ (1843) 11529 754.4 2.3e-216
XP_011531269 (OMIM: 260565,609736) PREDICTED: gird (1843) 11529 754.4 2.3e-216
XP_016859967 (OMIM: 260565,609736) PREDICTED: gird (1999) 11402 746.3 6.7e-214
XP_005264478 (OMIM: 260565,609736) PREDICTED: gird (1844) 10751 704.7 2.1e-201
XP_016859966 (OMIM: 260565,609736) PREDICTED: gird (2000) 10624 696.6 6.2e-199
XP_016859968 (OMIM: 260565,609736) PREDICTED: gird (1972) 9709 638.2 2.4e-181
XP_011531270 (OMIM: 260565,609736) PREDICTED: gird (1797) 9114 600.1 6.2e-170
XP_016859970 (OMIM: 260565,609736) PREDICTED: gird (1797) 9114 600.1 6.2e-170
XP_011531267 (OMIM: 260565,609736) PREDICTED: gird (1871) 9111 599.9 7.4e-170
XP_011531268 (OMIM: 260565,609736) PREDICTED: gird (1871) 9111 599.9 7.4e-170
XP_005264475 (OMIM: 260565,609736) PREDICTED: gird (2027) 9111 600.0 7.9e-170
NP_001241872 (OMIM: 260565,609736) girdin isoform (1796) 9097 599.0 1.3e-169
NP_001129069 (OMIM: 260565,609736) girdin isoform (1870) 9094 598.9 1.6e-169
XP_016859965 (OMIM: 260565,609736) PREDICTED: gird (2026) 9094 598.9 1.7e-169
XP_005264483 (OMIM: 260565,609736) PREDICTED: gird (1311) 8136 537.6 3.1e-151
XP_016859969 (OMIM: 260565,609736) PREDICTED: gird (1952) 7759 513.6 7.8e-144
XP_005267748 (OMIM: 236600,611204,616053) PREDICTE (1535) 5144 346.4 1.2e-93
XP_016876824 (OMIM: 236600,611204,616053) PREDICTE (1577) 5144 346.4 1.3e-93
NP_001073883 (OMIM: 236600,611204,616053) protein (2028) 5148 346.7 1.3e-93
XP_011535098 (OMIM: 236600,611204,616053) PREDICTE (1992) 5019 338.5 4e-91
XP_016876826 (OMIM: 236600,611204,616053) PREDICTE ( 921) 3430 236.8 7.4e-61
XP_016876825 (OMIM: 236600,611204,616053) PREDICTE (1055) 1691 125.7 2.3e-27
NP_115627 (OMIM: 611205) coiled-coil domain-contai (1476) 866 73.1 2.3e-11
XP_006718582 (OMIM: 611205) PREDICTED: coiled-coil (1560) 842 71.6 7e-11
XP_011543262 (OMIM: 611205) PREDICTED: coiled-coil (1528) 833 71.0 1e-10
XP_016873090 (OMIM: 611205) PREDICTED: coiled-coil ( 959) 822 70.2 1.1e-10
XP_011543261 (OMIM: 611205) PREDICTED: coiled-coil (1555) 688 61.7 6.4e-08
XP_011543259 (OMIM: 611205) PREDICTED: coiled-coil (1639) 664 60.2 1.9e-07
XP_011537117 (OMIM: 605070) PREDICTED: early endos (1365) 633 58.2 6.5e-07
XP_011537116 (OMIM: 605070) PREDICTED: early endos (1453) 633 58.2 6.9e-07
XP_016863148 (OMIM: 117143,616051) PREDICTED: cent (2551) 621 57.5 1.9e-06
XP_011529850 (OMIM: 117143,616051) PREDICTED: cent (2604) 594 55.8 6.5e-06
NP_001273663 (OMIM: 117143,616051) centromere-asso (2580) 590 55.6 7.7e-06
XP_011529849 (OMIM: 117143,616051) PREDICTED: cent (2605) 590 55.6 7.7e-06
NP_009044 (OMIM: 190370) trichohyalin [Homo sapien (1943) 570 54.2 1.5e-05
NP_115786 (OMIM: 607825) protein Hook homolog 3 [H ( 718) 547 52.6 1.7e-05
XP_016875507 (OMIM: 605070) PREDICTED: early endos (1417) 555 53.2 2.1e-05
NP_003557 (OMIM: 605070) early endosome antigen 1 (1411) 551 53.0 2.5e-05
XP_011543264 (OMIM: 611205) PREDICTED: coiled-coil ( 791) 534 51.8 3.2e-05
XP_016883107 (OMIM: 609689) PREDICTED: centrosome- (2198) 550 53.0 3.9e-05
XP_011526821 (OMIM: 609689) PREDICTED: centrosome- (2240) 550 53.0 4e-05
XP_011526820 (OMIM: 609689) PREDICTED: centrosome- (2319) 550 53.0 4.1e-05
XP_016883106 (OMIM: 609689) PREDICTED: centrosome- (2332) 550 53.0 4.1e-05
XP_011526819 (OMIM: 609689) PREDICTED: centrosome- (2355) 550 53.0 4.2e-05
XP_005260320 (OMIM: 609689) PREDICTED: centrosome- (2370) 550 53.0 4.2e-05
XP_006723757 (OMIM: 609689) PREDICTED: centrosome- (2404) 550 53.0 4.2e-05
XP_006723754 (OMIM: 609689) PREDICTED: centrosome- (2442) 550 53.0 4.3e-05
NP_009117 (OMIM: 609689) centrosome-associated pro (2442) 550 53.0 4.3e-05
XP_005260319 (OMIM: 609689) PREDICTED: centrosome- (2442) 550 53.0 4.3e-05
XP_006723753 (OMIM: 609689) PREDICTED: centrosome- (2442) 550 53.0 4.3e-05
>>NP_060554 (OMIM: 260565,609736) girdin isoform 2 [Homo (1843 aa)
initn: 11529 init1: 11529 opt: 11529 Z-score: 4005.5 bits: 754.4 E(85289): 2.3e-216
Smith-Waterman score: 11529; 100.0% identity (100.0% similar) in 1843 aa overlap (1-1843:1-1843)
10 20 30 40 50 60
pF1KE3 MENEIFTPLLEQFMTSPLVTWVKTFGPLAAGNGTNLDEYVALVDGVFLNQVMLQINPKLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 MENEIFTPLLEQFMTSPLVTWVKTFGPLAAGNGTNLDEYVALVDGVFLNQVMLQINPKLE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 SQRVNKKVNNDASLRMHNLSILVRQIKFYYQETLQQLIMMSLPNVLIIGKNPFSEQGTEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 SQRVNKKVNNDASLRMHNLSILVRQIKFYYQETLQQLIMMSLPNVLIIGKNPFSEQGTEE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 VKKLLLLLLGCAVQCQKKEEFIERIQGLDFDTKAAVAAHIQEVTHNQENVFDLQWMEVTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 VKKLLLLLLGCAVQCQKKEEFIERIQGLDFDTKAAVAAHIQEVTHNQENVFDLQWMEVTD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 MSQEDIEPLLKNMALHLKRLIDERDEHSETIIELSEERDGLHFLPHASSSAQSPCGSPGM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 MSQEDIEPLLKNMALHLKRLIDERDEHSETIIELSEERDGLHFLPHASSSAQSPCGSPGM
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 KRTESRQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 KRTESRQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 DARSARMYRDELDALREKAVRVDKLESEVSRYKERLHDIEFYKARVEELKEDNQVLLETK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 DARSARMYRDELDALREKAVRVDKLESEVSRYKERLHDIEFYKARVEELKEDNQVLLETK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 TMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 TMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQK
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 QSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 QSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELR
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 TTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 TTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEK
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 TIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 TIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETS
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 SKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEKIEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 SKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEKIEA
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 LEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 LEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKM
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 AQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 AQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQ
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE3 QLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 QLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKR
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE3 LRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 LRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATID
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE3 IKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDSRYKLLESK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 IKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDSRYKLLESK
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE3 LESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 LESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQSS
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE3 PPISGEDNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 PPISGEDNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQ
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE3 AQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 AQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENE
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE3 SVIKEREDLKSLYDSLIKDHEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHRDLED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 SVIKEREDLKSLYDSLIKDHEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHRDLED
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE3 RYNQLLKQKGQLEDLEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDRLNHTYSQLLKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 RYNQLLKQKGQLEDLEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDRLNHTYSQLLKE
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE3 TEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKGNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 TEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKGNL
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE3 EEENRHLLDQIQTLMLQNRTLLEQNMESKDLFHVEQRQYIDKLNELRRQKEKLEEKIMDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 EEENRHLLDQIQTLMLQNRTLLEQNMESKDLFHVEQRQYIDKLNELRRQKEKLEEKIMDQ
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KE3 YKFYDPSPPRRRGNWITLKMRKLIKSKKDINRERQKSLTLTPTRSDSSEGFLQLPHQDSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 YKFYDPSPPRRRGNWITLKMRKLIKSKKDINRERQKSLTLTPTRSDSSEGFLQLPHQDSQ
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KE3 DSSSVGSNSLEDGQTLGTKKSSTMNDLVQSMVLAGQWTGSTENLEVPDDISTGKRRKELG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 DSSSVGSNSLEDGQTLGTKKSSTMNDLVQSMVLAGQWTGSTENLEVPDDISTGKRRKELG
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KE3 AMAFSTTAINFSTVNSSAGFRSKQLVNNKDTTSFEDISPQGVSDDSSTGSRVHASRPASL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 AMAFSTTAINFSTVNSSAGFRSKQLVNNKDTTSFEDISPQGVSDDSSTGSRVHASRPASL
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KE3 DSGRTSTSNSNNNASLHEVKAGAVNNQSRPQSHSSGEFSLLHDHEAWSSSGSSPIQYLKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 DSGRTSTSNSNNNASLHEVKAGAVNNQSRPQSHSSGEFSLLHDHEAWSSSGSSPIQYLKR
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KE3 QTRSSPVLQHKISETLESRHHKIKTGSPGSEVVTLQQFLEESNKLTSVQIKSSSQENLLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 QTRSSPVLQHKISETLESRHHKIKTGSPGSEVVTLQQFLEESNKLTSVQIKSSSQENLLD
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730 1740
pF1KE3 EVMKSLSVSSDFLGKDKPVSCGLARSVSGKTPGDFYDRRTTKPEFLRPGPRKTEDTYFIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 EVMKSLSVSSDFLGKDKPVSCGLARSVSGKTPGDFYDRRTTKPEFLRPGPRKTEDTYFIS
1690 1700 1710 1720 1730 1740
1750 1760 1770 1780 1790 1800
pF1KE3 SAGKPTPGTQGKIKLVKESSLSRQSKDSNPYATLPRASSVISTAEGTTRRTSIHDFLTKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 SAGKPTPGTQGKIKLVKESSLSRQSKDSNPYATLPRASSVISTAEGTTRRTSIHDFLTKD
1750 1760 1770 1780 1790 1800
1810 1820 1830 1840
pF1KE3 SRLPISVDSPPAAADSNTTAASNVDKVQESRNSKSRSREQQSS
:::::::::::::::::::::::::::::::::::::::::::
NP_060 SRLPISVDSPPAAADSNTTAASNVDKVQESRNSKSRSREQQSS
1810 1820 1830 1840
>>XP_011531269 (OMIM: 260565,609736) PREDICTED: girdin i (1843 aa)
initn: 11529 init1: 11529 opt: 11529 Z-score: 4005.5 bits: 754.4 E(85289): 2.3e-216
Smith-Waterman score: 11529; 100.0% identity (100.0% similar) in 1843 aa overlap (1-1843:1-1843)
10 20 30 40 50 60
pF1KE3 MENEIFTPLLEQFMTSPLVTWVKTFGPLAAGNGTNLDEYVALVDGVFLNQVMLQINPKLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MENEIFTPLLEQFMTSPLVTWVKTFGPLAAGNGTNLDEYVALVDGVFLNQVMLQINPKLE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 SQRVNKKVNNDASLRMHNLSILVRQIKFYYQETLQQLIMMSLPNVLIIGKNPFSEQGTEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SQRVNKKVNNDASLRMHNLSILVRQIKFYYQETLQQLIMMSLPNVLIIGKNPFSEQGTEE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 VKKLLLLLLGCAVQCQKKEEFIERIQGLDFDTKAAVAAHIQEVTHNQENVFDLQWMEVTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VKKLLLLLLGCAVQCQKKEEFIERIQGLDFDTKAAVAAHIQEVTHNQENVFDLQWMEVTD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 MSQEDIEPLLKNMALHLKRLIDERDEHSETIIELSEERDGLHFLPHASSSAQSPCGSPGM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSQEDIEPLLKNMALHLKRLIDERDEHSETIIELSEERDGLHFLPHASSSAQSPCGSPGM
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 KRTESRQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KRTESRQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 DARSARMYRDELDALREKAVRVDKLESEVSRYKERLHDIEFYKARVEELKEDNQVLLETK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DARSARMYRDELDALREKAVRVDKLESEVSRYKERLHDIEFYKARVEELKEDNQVLLETK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 TMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQK
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 QSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELR
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 TTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEK
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 TIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETS
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 SKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEKIEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEKIEA
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 LEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKM
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 AQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQ
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE3 QLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKR
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE3 LRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATID
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE3 IKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDSRYKLLESK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDSRYKLLESK
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE3 LESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQSS
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE3 PPISGEDNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPISGEDNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQ
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE3 AQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENE
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE3 SVIKEREDLKSLYDSLIKDHEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHRDLED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SVIKEREDLKSLYDSLIKDHEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHRDLED
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE3 RYNQLLKQKGQLEDLEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDRLNHTYSQLLKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RYNQLLKQKGQLEDLEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDRLNHTYSQLLKE
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE3 TEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKGNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKGNL
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE3 EEENRHLLDQIQTLMLQNRTLLEQNMESKDLFHVEQRQYIDKLNELRRQKEKLEEKIMDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEENRHLLDQIQTLMLQNRTLLEQNMESKDLFHVEQRQYIDKLNELRRQKEKLEEKIMDQ
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KE3 YKFYDPSPPRRRGNWITLKMRKLIKSKKDINRERQKSLTLTPTRSDSSEGFLQLPHQDSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YKFYDPSPPRRRGNWITLKMRKLIKSKKDINRERQKSLTLTPTRSDSSEGFLQLPHQDSQ
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KE3 DSSSVGSNSLEDGQTLGTKKSSTMNDLVQSMVLAGQWTGSTENLEVPDDISTGKRRKELG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DSSSVGSNSLEDGQTLGTKKSSTMNDLVQSMVLAGQWTGSTENLEVPDDISTGKRRKELG
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KE3 AMAFSTTAINFSTVNSSAGFRSKQLVNNKDTTSFEDISPQGVSDDSSTGSRVHASRPASL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AMAFSTTAINFSTVNSSAGFRSKQLVNNKDTTSFEDISPQGVSDDSSTGSRVHASRPASL
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KE3 DSGRTSTSNSNNNASLHEVKAGAVNNQSRPQSHSSGEFSLLHDHEAWSSSGSSPIQYLKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DSGRTSTSNSNNNASLHEVKAGAVNNQSRPQSHSSGEFSLLHDHEAWSSSGSSPIQYLKR
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KE3 QTRSSPVLQHKISETLESRHHKIKTGSPGSEVVTLQQFLEESNKLTSVQIKSSSQENLLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QTRSSPVLQHKISETLESRHHKIKTGSPGSEVVTLQQFLEESNKLTSVQIKSSSQENLLD
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730 1740
pF1KE3 EVMKSLSVSSDFLGKDKPVSCGLARSVSGKTPGDFYDRRTTKPEFLRPGPRKTEDTYFIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EVMKSLSVSSDFLGKDKPVSCGLARSVSGKTPGDFYDRRTTKPEFLRPGPRKTEDTYFIS
1690 1700 1710 1720 1730 1740
1750 1760 1770 1780 1790 1800
pF1KE3 SAGKPTPGTQGKIKLVKESSLSRQSKDSNPYATLPRASSVISTAEGTTRRTSIHDFLTKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SAGKPTPGTQGKIKLVKESSLSRQSKDSNPYATLPRASSVISTAEGTTRRTSIHDFLTKD
1750 1760 1770 1780 1790 1800
1810 1820 1830 1840
pF1KE3 SRLPISVDSPPAAADSNTTAASNVDKVQESRNSKSRSREQQSS
:::::::::::::::::::::::::::::::::::::::::::
XP_011 SRLPISVDSPPAAADSNTTAASNVDKVQESRNSKSRSREQQSS
1810 1820 1830 1840
>>XP_016859967 (OMIM: 260565,609736) PREDICTED: girdin i (1999 aa)
initn: 11823 init1: 11402 opt: 11402 Z-score: 3961.1 bits: 746.3 E(85289): 6.7e-214
Smith-Waterman score: 11402; 99.9% identity (100.0% similar) in 1823 aa overlap (1-1823:1-1823)
10 20 30 40 50 60
pF1KE3 MENEIFTPLLEQFMTSPLVTWVKTFGPLAAGNGTNLDEYVALVDGVFLNQVMLQINPKLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MENEIFTPLLEQFMTSPLVTWVKTFGPLAAGNGTNLDEYVALVDGVFLNQVMLQINPKLE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 SQRVNKKVNNDASLRMHNLSILVRQIKFYYQETLQQLIMMSLPNVLIIGKNPFSEQGTEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SQRVNKKVNNDASLRMHNLSILVRQIKFYYQETLQQLIMMSLPNVLIIGKNPFSEQGTEE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 VKKLLLLLLGCAVQCQKKEEFIERIQGLDFDTKAAVAAHIQEVTHNQENVFDLQWMEVTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VKKLLLLLLGCAVQCQKKEEFIERIQGLDFDTKAAVAAHIQEVTHNQENVFDLQWMEVTD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 MSQEDIEPLLKNMALHLKRLIDERDEHSETIIELSEERDGLHFLPHASSSAQSPCGSPGM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSQEDIEPLLKNMALHLKRLIDERDEHSETIIELSEERDGLHFLPHASSSAQSPCGSPGM
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 KRTESRQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KRTESRQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 DARSARMYRDELDALREKAVRVDKLESEVSRYKERLHDIEFYKARVEELKEDNQVLLETK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DARSARMYRDELDALREKAVRVDKLESEVSRYKERLHDIEFYKARVEELKEDNQVLLETK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 TMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQK
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 QSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELR
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 TTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEK
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 TIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETS
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 SKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEKIEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEKIEA
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 LEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKM
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 AQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQ
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE3 QLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKR
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE3 LRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATID
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE3 IKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDSRYKLLESK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDSRYKLLESK
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE3 LESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQSS
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE3 PPISGEDNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPISGEDNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQ
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE3 AQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENE
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE3 SVIKEREDLKSLYDSLIKDHEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHRDLED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVIKEREDLKSLYDSLIKDHEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHRDLED
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE3 RYNQLLKQKGQLEDLEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDRLNHTYSQLLKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RYNQLLKQKGQLEDLEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDRLNHTYSQLLKE
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE3 TEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKGNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKGNL
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE3 EEENRHLLDQIQTLMLQNRTLLEQNMESKDLFHVEQRQYIDKLNELRRQKEKLEEKIMDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEENRHLLDQIQTLMLQNRTLLEQNMESKDLFHVEQRQYIDKLNELRRQKEKLEEKIMDQ
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KE3 YKFYDPSPPRRRGNWITLKMRKLIKSKKDINRERQKSLTLTPTRSDSSEGFLQLPHQDSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YKFYDPSPPRRRGNWITLKMRKLIKSKKDINRERQKSLTLTPTRSDSSEGFLQLPHQDSQ
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KE3 DSSSVGSNSLEDGQTLGTKKSSTMNDLVQSMVLAGQWTGSTENLEVPDDISTGKRRKELG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DSSSVGSNSLEDGQTLGTKKSSTMNDLVQSMVLAGQWTGSTENLEVPDDISTGKRRKELG
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KE3 AMAFSTTAINFSTVNSSAGFRSKQLVNNKDTTSFEDISPQGVSDDSSTGSRVHASRPASL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AMAFSTTAINFSTVNSSAGFRSKQLVNNKDTTSFEDISPQGVSDDSSTGSRVHASRPASL
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KE3 DSGRTSTSNSNNNASLHEVKAGAVNNQSRPQSHSSGEFSLLHDHEAWSSSGSSPIQYLKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DSGRTSTSNSNNNASLHEVKAGAVNNQSRPQSHSSGEFSLLHDHEAWSSSGSSPIQYLKR
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KE3 QTRSSPVLQHKISETLESRHHKIKTGSPGSEVVTLQQFLEESNKLTSVQIKSSSQENLLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QTRSSPVLQHKISETLESRHHKIKTGSPGSEVVTLQQFLEESNKLTSVQIKSSSQENLLD
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730 1740
pF1KE3 EVMKSLSVSSDFLGKDKPVSCGLARSVSGKTPGDFYDRRTTKPEFLRPGPRKTEDTYFIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EVMKSLSVSSDFLGKDKPVSCGLARSVSGKTPGDFYDRRTTKPEFLRPGPRKTEDTYFIS
1690 1700 1710 1720 1730 1740
1750 1760 1770 1780 1790 1800
pF1KE3 SAGKPTPGTQGKIKLVKESSLSRQSKDSNPYATLPRASSVISTAEGTTRRTSIHDFLTKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SAGKPTPGTQGKIKLVKESSLSRQSKDSNPYATLPRASSVISTAEGTTRRTSIHDFLTKD
1750 1760 1770 1780 1790 1800
1810 1820 1830 1840
pF1KE3 SRLPISVDSPPAAADSNTTAASNVDKVQESRNSKSRSREQQSS
::::::::::::::::::::::.
XP_016 SRLPISVDSPPAAADSNTTAASSEYHLHQWSSHILDIPTHTIGSCAQNDLAIDMPEPLYA
1810 1820 1830 1840 1850 1860
>>XP_005264478 (OMIM: 260565,609736) PREDICTED: girdin i (1844 aa)
initn: 10779 init1: 9111 opt: 10751 Z-score: 3736.9 bits: 704.7 E(85289): 2.1e-201
Smith-Waterman score: 11231; 97.0% identity (97.1% similar) in 1871 aa overlap (1-1843:1-1844)
10 20 30 40 50 60
pF1KE3 MENEIFTPLLEQFMTSPLVTWVKTFGPLAAGNGTNLDEYVALVDGVFLNQVMLQINPKLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MENEIFTPLLEQFMTSPLVTWVKTFGPLAAGNGTNLDEYVALVDGVFLNQVMLQINPKLE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 SQRVNKKVNNDASLRMHNLSILVRQIKFYYQETLQQLIMMSLPNVLIIGKNPFSEQGTEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SQRVNKKVNNDASLRMHNLSILVRQIKFYYQETLQQLIMMSLPNVLIIGKNPFSEQGTEE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 VKKLLLLLLGCAVQCQKKEEFIERIQGLDFDTKAAVAAHIQEVTHNQENVFDLQWMEVTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VKKLLLLLLGCAVQCQKKEEFIERIQGLDFDTKAAVAAHIQEVTHNQENVFDLQWMEVTD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 MSQEDIEPLLKNMALHLKRLIDERDEHSETIIELSEERDGLHFLPHASSSAQSPCGSPGM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MSQEDIEPLLKNMALHLKRLIDERDEHSETIIELSEERDGLHFLPHASSSAQSPCGSPGM
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 KRTESRQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KRTESRQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 DARSARMYRDELDALREKAVRVDKLESEVSRYKERLHDIEFYKARVEELKEDNQVLLETK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DARSARMYRDELDALREKAVRVDKLESEVSRYKERLHDIEFYKARVEELKEDNQVLLETK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 TMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQK
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 QSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELR
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 TTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEK
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 TIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETS
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 SKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEKIEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEKIEA
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 LEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKM
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 AQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQ
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE3 QLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKR
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE3 LRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATID
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE3 IKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDSRYKLLESK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDSRYKLLESK
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE3 LESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQSS
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE3 PPISGEDNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PPISGEDNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQ
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE3 AQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENE
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE3 SVIKEREDLKSLYDSLIKDHEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHRDLED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SVIKEREDLKSLYDSLIKDHEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHRDLED
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE3 RYNQLLKQKGQLEDLEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDRLNHTYSQLLKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RYNQLLKQKGQLEDLEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDRLNHTYSQLLKE
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE3 TEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKGNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKGNL
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE3 EEENRHLLDQIQTLMLQNRTLLEQNMESKDLFHVEQRQYIDKLNELRRQKEKLEEKIMDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EEENRHLLDQIQTLMLQNRTLLEQNMESKDLFHVEQRQYIDKLNELRRQKEKLEEKIMDQ
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KE3 YKFYDPSPPRRRGNWITLKMRKLIKSKKDINRERQKSLTLTPTRSDSSEGFLQLPHQDSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YKFYDPSPPRRRGNWITLKMRKLIKSKKDINRERQKSLTLTPTRSDSSEGFLQLPHQDSQ
1390 1400 1410 1420 1430 1440
1450 1460 1470
pF1KE3 DSSSVGSNSLEDGQTLGTKKSS----------------------------TMNDLVQSMV
:::::::::::::::::::::: .:::::::::
XP_005 DSSSVGSNSLEDGQTLGTKKSSMVALKRLPFLRNRPKDKDKMKACYRRSMSMNDLVQSMV
1450 1460 1470 1480 1490 1500
1480 1490 1500 1510 1520 1530
pF1KE3 LAGQWTGSTENLEVPDDISTGKRRKELGAMAFSTTAINFSTVNSSAGFRSKQLVNNKDTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LAGQWTGSTENLEVPDDISTGKRRKELGAMAFSTTAINFSTVNSSAGFRSKQLVNNKDTT
1510 1520 1530 1540 1550 1560
1540 1550 1560 1570 1580 1590
pF1KE3 SFEDISPQGVSDDSSTGSRVHASRPASLDSGRTSTSNSNNNASLHEVKAGAVNNQSRPQS
:::::::::::::::::::::: :::::::::::
XP_005 SFEDISPQGVSDDSSTGSRVHA---------------------------GAVNNQSRPQS
1570 1580 1590
1600 1610 1620 1630 1640 1650
pF1KE3 HSSGEFSLLHDHEAWSSSGSSPIQYLKRQTRSSPVLQHKISETLESRHHKIKTGSPGSEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HSSGEFSLLHDHEAWSSSGSSPIQYLKRQTRSSPVLQHKISETLESRHHKIKTGSPGSEV
1600 1610 1620 1630 1640 1650
1660 1670 1680 1690 1700 1710
pF1KE3 VTLQQFLEESNKLTSVQIKSSSQENLLDEVMKSLSVSSDFLGKDKPVSCGLARSVSGKTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VTLQQFLEESNKLTSVQIKSSSQENLLDEVMKSLSVSSDFLGKDKPVSCGLARSVSGKTP
1660 1670 1680 1690 1700 1710
1720 1730 1740 1750 1760 1770
pF1KE3 GDFYDRRTTKPEFLRPGPRKTEDTYFISSAGKPTPGTQGKIKLVKESSLSRQSKDSNPYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GDFYDRRTTKPEFLRPGPRKTEDTYFISSAGKPTPGTQGKIKLVKESSLSRQSKDSNPYA
1720 1730 1740 1750 1760 1770
1780 1790 1800 1810 1820 1830
pF1KE3 TLPRASSVISTAEGTTRRTSIHDFLTKDSRLPISVDSPPAAADSNTTAASNVDKVQESRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TLPRASSVISTAEGTTRRTSIHDFLTKDSRLPISVDSPPAAADSNTTAASNVDKVQESRN
1780 1790 1800 1810 1820 1830
1840
pF1KE3 SKSRSREQQSS
:::::::::::
XP_005 SKSRSREQQSS
1840
>>XP_016859966 (OMIM: 260565,609736) PREDICTED: girdin i (2000 aa)
initn: 10647 init1: 9111 opt: 10624 Z-score: 3692.5 bits: 696.6 E(85289): 6.2e-199
Smith-Waterman score: 11104; 96.9% identity (97.0% similar) in 1851 aa overlap (1-1823:1-1824)
10 20 30 40 50 60
pF1KE3 MENEIFTPLLEQFMTSPLVTWVKTFGPLAAGNGTNLDEYVALVDGVFLNQVMLQINPKLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MENEIFTPLLEQFMTSPLVTWVKTFGPLAAGNGTNLDEYVALVDGVFLNQVMLQINPKLE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 SQRVNKKVNNDASLRMHNLSILVRQIKFYYQETLQQLIMMSLPNVLIIGKNPFSEQGTEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SQRVNKKVNNDASLRMHNLSILVRQIKFYYQETLQQLIMMSLPNVLIIGKNPFSEQGTEE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 VKKLLLLLLGCAVQCQKKEEFIERIQGLDFDTKAAVAAHIQEVTHNQENVFDLQWMEVTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VKKLLLLLLGCAVQCQKKEEFIERIQGLDFDTKAAVAAHIQEVTHNQENVFDLQWMEVTD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 MSQEDIEPLLKNMALHLKRLIDERDEHSETIIELSEERDGLHFLPHASSSAQSPCGSPGM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSQEDIEPLLKNMALHLKRLIDERDEHSETIIELSEERDGLHFLPHASSSAQSPCGSPGM
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 KRTESRQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KRTESRQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 DARSARMYRDELDALREKAVRVDKLESEVSRYKERLHDIEFYKARVEELKEDNQVLLETK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DARSARMYRDELDALREKAVRVDKLESEVSRYKERLHDIEFYKARVEELKEDNQVLLETK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 TMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQK
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 QSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELR
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 TTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEK
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 TIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETS
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 SKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEKIEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEKIEA
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 LEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKM
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 AQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQ
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE3 QLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKR
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE3 LRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATID
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE3 IKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDSRYKLLESK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDSRYKLLESK
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE3 LESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQSS
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE3 PPISGEDNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPISGEDNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQ
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE3 AQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENE
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE3 SVIKEREDLKSLYDSLIKDHEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHRDLED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVIKEREDLKSLYDSLIKDHEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHRDLED
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE3 RYNQLLKQKGQLEDLEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDRLNHTYSQLLKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RYNQLLKQKGQLEDLEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDRLNHTYSQLLKE
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE3 TEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKGNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKGNL
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE3 EEENRHLLDQIQTLMLQNRTLLEQNMESKDLFHVEQRQYIDKLNELRRQKEKLEEKIMDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEENRHLLDQIQTLMLQNRTLLEQNMESKDLFHVEQRQYIDKLNELRRQKEKLEEKIMDQ
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KE3 YKFYDPSPPRRRGNWITLKMRKLIKSKKDINRERQKSLTLTPTRSDSSEGFLQLPHQDSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YKFYDPSPPRRRGNWITLKMRKLIKSKKDINRERQKSLTLTPTRSDSSEGFLQLPHQDSQ
1390 1400 1410 1420 1430 1440
1450 1460 1470
pF1KE3 DSSSVGSNSLEDGQTLGTKKSS----------------------------TMNDLVQSMV
:::::::::::::::::::::: .:::::::::
XP_016 DSSSVGSNSLEDGQTLGTKKSSMVALKRLPFLRNRPKDKDKMKACYRRSMSMNDLVQSMV
1450 1460 1470 1480 1490 1500
1480 1490 1500 1510 1520 1530
pF1KE3 LAGQWTGSTENLEVPDDISTGKRRKELGAMAFSTTAINFSTVNSSAGFRSKQLVNNKDTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAGQWTGSTENLEVPDDISTGKRRKELGAMAFSTTAINFSTVNSSAGFRSKQLVNNKDTT
1510 1520 1530 1540 1550 1560
1540 1550 1560 1570 1580 1590
pF1KE3 SFEDISPQGVSDDSSTGSRVHASRPASLDSGRTSTSNSNNNASLHEVKAGAVNNQSRPQS
:::::::::::::::::::::: :::::::::::
XP_016 SFEDISPQGVSDDSSTGSRVHA---------------------------GAVNNQSRPQS
1570 1580 1590
1600 1610 1620 1630 1640 1650
pF1KE3 HSSGEFSLLHDHEAWSSSGSSPIQYLKRQTRSSPVLQHKISETLESRHHKIKTGSPGSEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HSSGEFSLLHDHEAWSSSGSSPIQYLKRQTRSSPVLQHKISETLESRHHKIKTGSPGSEV
1600 1610 1620 1630 1640 1650
1660 1670 1680 1690 1700 1710
pF1KE3 VTLQQFLEESNKLTSVQIKSSSQENLLDEVMKSLSVSSDFLGKDKPVSCGLARSVSGKTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VTLQQFLEESNKLTSVQIKSSSQENLLDEVMKSLSVSSDFLGKDKPVSCGLARSVSGKTP
1660 1670 1680 1690 1700 1710
1720 1730 1740 1750 1760 1770
pF1KE3 GDFYDRRTTKPEFLRPGPRKTEDTYFISSAGKPTPGTQGKIKLVKESSLSRQSKDSNPYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GDFYDRRTTKPEFLRPGPRKTEDTYFISSAGKPTPGTQGKIKLVKESSLSRQSKDSNPYA
1720 1730 1740 1750 1760 1770
1780 1790 1800 1810 1820 1830
pF1KE3 TLPRASSVISTAEGTTRRTSIHDFLTKDSRLPISVDSPPAAADSNTTAASNVDKVQESRN
::::::::::::::::::::::::::::::::::::::::::::::::::.
XP_016 TLPRASSVISTAEGTTRRTSIHDFLTKDSRLPISVDSPPAAADSNTTAASSEYHLHQWSS
1780 1790 1800 1810 1820 1830
1840
pF1KE3 SKSRSREQQSS
XP_016 HILDIPTHTIGSCAQNDLAIDMPEPLYAQARNSRTGRSHFLNQTFATIRMPSDAFGMLAK
1840 1850 1860 1870 1880 1890
>>XP_016859968 (OMIM: 260565,609736) PREDICTED: girdin i (1972 aa)
initn: 11228 init1: 9692 opt: 9709 Z-score: 3376.6 bits: 638.2 E(85289): 2.4e-181
Smith-Waterman score: 11173; 98.5% identity (98.5% similar) in 1823 aa overlap (1-1823:1-1796)
10 20 30 40 50 60
pF1KE3 MENEIFTPLLEQFMTSPLVTWVKTFGPLAAGNGTNLDEYVALVDGVFLNQVMLQINPKLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MENEIFTPLLEQFMTSPLVTWVKTFGPLAAGNGTNLDEYVALVDGVFLNQVMLQINPKLE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 SQRVNKKVNNDASLRMHNLSILVRQIKFYYQETLQQLIMMSLPNVLIIGKNPFSEQGTEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SQRVNKKVNNDASLRMHNLSILVRQIKFYYQETLQQLIMMSLPNVLIIGKNPFSEQGTEE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 VKKLLLLLLGCAVQCQKKEEFIERIQGLDFDTKAAVAAHIQEVTHNQENVFDLQWMEVTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VKKLLLLLLGCAVQCQKKEEFIERIQGLDFDTKAAVAAHIQEVTHNQENVFDLQWMEVTD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 MSQEDIEPLLKNMALHLKRLIDERDEHSETIIELSEERDGLHFLPHASSSAQSPCGSPGM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSQEDIEPLLKNMALHLKRLIDERDEHSETIIELSEERDGLHFLPHASSSAQSPCGSPGM
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 KRTESRQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KRTESRQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 DARSARMYRDELDALREKAVRVDKLESEVSRYKERLHDIEFYKARVEELKEDNQVLLETK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DARSARMYRDELDALREKAVRVDKLESEVSRYKERLHDIEFYKARVEELKEDNQVLLETK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 TMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQK
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 QSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELR
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 TTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEK
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 TIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETS
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 SKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEKIEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEKIEA
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 LEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKM
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 AQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQ
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE3 QLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKR
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE3 LRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATID
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE3 IKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDSRYKLLESK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDSRYKLLESK
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE3 LESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQSS
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE3 PPISGEDNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPISGEDNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQ
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE3 AQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENE
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE3 SVIKEREDLKSLYDSLIKDHEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHRDLED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVIKEREDLKSLYDSLIKDHEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHRDLED
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE3 RYNQLLKQKGQLEDLEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDRLNHTYSQLLKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RYNQLLKQKGQLEDLEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDRLNHTYSQLLKE
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE3 TEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKGNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKGNL
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE3 EEENRHLLDQIQTLMLQNRTLLEQNMESKDLFHVEQRQYIDKLNELRRQKEKLEEKIMDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEENRHLLDQIQTLMLQNRTLLEQNMESKDLFHVEQRQYIDKLNELRRQKEKLEEKIMDQ
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KE3 YKFYDPSPPRRRGNWITLKMRKLIKSKKDINRERQKSLTLTPTRSDSSEGFLQLPHQDSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YKFYDPSPPRRRGNWITLKMRKLIKSKKDINRERQKSLTLTPTRSDSSEGFLQLPHQDSQ
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KE3 DSSSVGSNSLEDGQTLGTKKSSTMNDLVQSMVLAGQWTGSTENLEVPDDISTGKRRKELG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DSSSVGSNSLEDGQTLGTKKSSTMNDLVQSMVLAGQWTGSTENLEVPDDISTGKRRKELG
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KE3 AMAFSTTAINFSTVNSSAGFRSKQLVNNKDTTSFEDISPQGVSDDSSTGSRVHASRPASL
::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AMAFSTTAINFSTVNSSAGFRSKQLVNNKDTTSFEDISPQGVSDDSSTGSRVHA------
1510 1520 1530 1540 1550
1570 1580 1590 1600 1610 1620
pF1KE3 DSGRTSTSNSNNNASLHEVKAGAVNNQSRPQSHSSGEFSLLHDHEAWSSSGSSPIQYLKR
:::::::::::::::::::::::::::::::::::::::
XP_016 ---------------------GAVNNQSRPQSHSSGEFSLLHDHEAWSSSGSSPIQYLKR
1560 1570 1580 1590
1630 1640 1650 1660 1670 1680
pF1KE3 QTRSSPVLQHKISETLESRHHKIKTGSPGSEVVTLQQFLEESNKLTSVQIKSSSQENLLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QTRSSPVLQHKISETLESRHHKIKTGSPGSEVVTLQQFLEESNKLTSVQIKSSSQENLLD
1600 1610 1620 1630 1640 1650
1690 1700 1710 1720 1730 1740
pF1KE3 EVMKSLSVSSDFLGKDKPVSCGLARSVSGKTPGDFYDRRTTKPEFLRPGPRKTEDTYFIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EVMKSLSVSSDFLGKDKPVSCGLARSVSGKTPGDFYDRRTTKPEFLRPGPRKTEDTYFIS
1660 1670 1680 1690 1700 1710
1750 1760 1770 1780 1790 1800
pF1KE3 SAGKPTPGTQGKIKLVKESSLSRQSKDSNPYATLPRASSVISTAEGTTRRTSIHDFLTKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SAGKPTPGTQGKIKLVKESSLSRQSKDSNPYATLPRASSVISTAEGTTRRTSIHDFLTKD
1720 1730 1740 1750 1760 1770
1810 1820 1830 1840
pF1KE3 SRLPISVDSPPAAADSNTTAASNVDKVQESRNSKSRSREQQSS
::::::::::::::::::::::.
XP_016 SRLPISVDSPPAAADSNTTAASSEYHLHQWSSHILDIPTHTIGSCAQNDLAIDMPEPLYA
1780 1790 1800 1810 1820 1830
>>XP_011531270 (OMIM: 260565,609736) PREDICTED: girdin i (1797 aa)
initn: 10631 init1: 9111 opt: 9114 Z-score: 3171.8 bits: 600.1 E(85289): 6.2e-170
Smith-Waterman score: 10813; 94.5% identity (94.5% similar) in 1871 aa overlap (1-1843:1-1797)
10 20 30 40 50 60
pF1KE3 MENEIFTPLLEQFMTSPLVTWVKTFGPLAAGNGTNLDEYVALVDGVFLNQVMLQINPKLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MENEIFTPLLEQFMTSPLVTWVKTFGPLAAGNGTNLDEYVALVDGVFLNQVMLQINPKLE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 SQRVNKKVNNDASLRMHNLSILVRQIKFYYQETLQQLIMMSLPNVLIIGKNPFSEQGTEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SQRVNKKVNNDASLRMHNLSILVRQIKFYYQETLQQLIMMSLPNVLIIGKNPFSEQGTEE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 VKKLLLLLLGCAVQCQKKEEFIERIQGLDFDTKAAVAAHIQEVTHNQENVFDLQWMEVTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VKKLLLLLLGCAVQCQKKEEFIERIQGLDFDTKAAVAAHIQEVTHNQENVFDLQWMEVTD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 MSQEDIEPLLKNMALHLKRLIDERDEHSETIIELSEERDGLHFLPHASSSAQSPCGSPGM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSQEDIEPLLKNMALHLKRLIDERDEHSETIIELSEERDGLHFLPHASSSAQSPCGSPGM
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 KRTESRQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KRTESRQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 DARSARMYRDELDALREKAVRVDKLESEVSRYKERLHDIEFYKARVEELKEDNQVLLETK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DARSARMYRDELDALREKAVRVDKLESEVSRYKERLHDIEFYKARVEELKEDNQVLLETK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 TMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQK
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 QSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELR
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 TTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEK
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 TIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETS
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 SKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEKIEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEKIEA
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 LEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKM
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 AQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQ
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE3 QLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKR
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE3 LRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATID
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE3 IKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDSRYKLLESK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDSRYKLLESK
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE3 LESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQSS
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE3 PPISGEDNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPISGEDNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQ
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE3 AQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENE
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE3 SVIKEREDLKSLYDSLIKDHEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHRDLED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SVIKEREDLKSLYDSLIKDHEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHRDLED
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE3 RYNQLLKQKGQLEDLEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDRLNHTYSQLLKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RYNQLLKQKGQLEDLEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDRLNHTYSQLLKE
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE3 TEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKGNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKGNL
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE3 EEENRHLLDQIQTLMLQNRTLLEQNMESKDLFHVEQRQYIDKLNELRRQKEKLEEKIMDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEENRHLLDQIQTLMLQNRTLLEQNMESKDLFHVEQRQYIDKLNELRRQKEKLEEKIMDQ
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KE3 YKFYDPSPPRRRGNWITLKMRKLIKSKKDINRERQKSLTLTPTRSDSSEGFLQLPHQDSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YKFYDPSPPRRRGNWITLKMRKLIKSKKDINRERQKSLTLTPTRSDSSEGFLQLPHQDSQ
1390 1400 1410 1420 1430 1440
1450 1460 1470
pF1KE3 DSSSVGSNSLEDGQTLGTKKSS----------------------------TMNDLVQSMV
:::::::::::::::::::::: .:::::::::
XP_011 DSSSVGSNSLEDGQTLGTKKSSMVALKRLPFLRNRPKDKDKMKACYRRSMSMNDLVQSMV
1450 1460 1470 1480 1490 1500
1480 1490 1500 1510 1520 1530
pF1KE3 LAGQWTGSTENLEVPDDISTGKRRKELGAMAFSTTAINFSTVNSSAGFRSKQLVNNKDTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LAGQWTGSTENLEVPDDISTGKRRKELGAMAFSTTAINFSTVNSSAGFRSKQLVNNKDTT
1510 1520 1530 1540 1550 1560
1540 1550 1560 1570 1580 1590
pF1KE3 SFEDISPQGVSDDSSTGSRVHASRPASLDSGRTSTSNSNNNASLHEVKAGAVNNQSRPQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SFEDISPQGVSDDSSTGSRVHASRPASLDSGRTSTSNSNNNASLHEVKAGAVNNQSRPQS
1570 1580 1590 1600 1610 1620
1600 1610 1620 1630 1640 1650
pF1KE3 HSSGEFSLLHDHEAWSSSGSSPIQYLKRQTRSSPVLQHKISETLESRHHKIKTGSPGSEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HSSGEFSLLHDHEAWSSSGSSPIQYLKRQTRSSPVLQHKISETLESRHHKIKTGSPGSEV
1630 1640 1650 1660 1670 1680
1660 1670 1680 1690 1700 1710
pF1KE3 VTLQQFLEESNKLTSVQIKSSSQENLLDEVMKSLSVSSDFLGKDKPVSCGLARSVSGKTP
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VTLQQFLEESNKLTSVQIKSSSQENLLDEVMKSLSVSSDFLGKDKPVSCGLA--------
1690 1700 1710 1720 1730
1720 1730 1740 1750 1760 1770
pF1KE3 GDFYDRRTTKPEFLRPGPRKTEDTYFISSAGKPTPGTQGKIKLVKESSLSRQSKDSNPYA
XP_011 ------------------------------------------------------------
1780 1790 1800 1810 1820 1830
pF1KE3 TLPRASSVISTAEGTTRRTSIHDFLTKDSRLPISVDSPPAAADSNTTAASNVDKVQESRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ------SVISTAEGTTRRTSIHDFLTKDSRLPISVDSPPAAADSNTTAASNVDKVQESRN
1740 1750 1760 1770 1780
1840
pF1KE3 SKSRSREQQSS
:::::::::::
XP_011 SKSRSREQQSS
1790
>>XP_016859970 (OMIM: 260565,609736) PREDICTED: girdin i (1797 aa)
initn: 10631 init1: 9111 opt: 9114 Z-score: 3171.8 bits: 600.1 E(85289): 6.2e-170
Smith-Waterman score: 10813; 94.5% identity (94.5% similar) in 1871 aa overlap (1-1843:1-1797)
10 20 30 40 50 60
pF1KE3 MENEIFTPLLEQFMTSPLVTWVKTFGPLAAGNGTNLDEYVALVDGVFLNQVMLQINPKLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MENEIFTPLLEQFMTSPLVTWVKTFGPLAAGNGTNLDEYVALVDGVFLNQVMLQINPKLE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 SQRVNKKVNNDASLRMHNLSILVRQIKFYYQETLQQLIMMSLPNVLIIGKNPFSEQGTEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SQRVNKKVNNDASLRMHNLSILVRQIKFYYQETLQQLIMMSLPNVLIIGKNPFSEQGTEE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 VKKLLLLLLGCAVQCQKKEEFIERIQGLDFDTKAAVAAHIQEVTHNQENVFDLQWMEVTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VKKLLLLLLGCAVQCQKKEEFIERIQGLDFDTKAAVAAHIQEVTHNQENVFDLQWMEVTD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 MSQEDIEPLLKNMALHLKRLIDERDEHSETIIELSEERDGLHFLPHASSSAQSPCGSPGM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSQEDIEPLLKNMALHLKRLIDERDEHSETIIELSEERDGLHFLPHASSSAQSPCGSPGM
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 KRTESRQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KRTESRQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 DARSARMYRDELDALREKAVRVDKLESEVSRYKERLHDIEFYKARVEELKEDNQVLLETK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DARSARMYRDELDALREKAVRVDKLESEVSRYKERLHDIEFYKARVEELKEDNQVLLETK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 TMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQK
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 QSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELR
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 TTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEK
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 TIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETS
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 SKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEKIEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEKIEA
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 LEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKM
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 AQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQ
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE3 QLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKR
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE3 LRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATID
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE3 IKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDSRYKLLESK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDSRYKLLESK
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE3 LESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQSS
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE3 PPISGEDNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPISGEDNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQ
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE3 AQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENE
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE3 SVIKEREDLKSLYDSLIKDHEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHRDLED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVIKEREDLKSLYDSLIKDHEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHRDLED
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE3 RYNQLLKQKGQLEDLEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDRLNHTYSQLLKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RYNQLLKQKGQLEDLEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDRLNHTYSQLLKE
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE3 TEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKGNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKGNL
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE3 EEENRHLLDQIQTLMLQNRTLLEQNMESKDLFHVEQRQYIDKLNELRRQKEKLEEKIMDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEENRHLLDQIQTLMLQNRTLLEQNMESKDLFHVEQRQYIDKLNELRRQKEKLEEKIMDQ
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KE3 YKFYDPSPPRRRGNWITLKMRKLIKSKKDINRERQKSLTLTPTRSDSSEGFLQLPHQDSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YKFYDPSPPRRRGNWITLKMRKLIKSKKDINRERQKSLTLTPTRSDSSEGFLQLPHQDSQ
1390 1400 1410 1420 1430 1440
1450 1460 1470
pF1KE3 DSSSVGSNSLEDGQTLGTKKSS----------------------------TMNDLVQSMV
:::::::::::::::::::::: .:::::::::
XP_016 DSSSVGSNSLEDGQTLGTKKSSMVALKRLPFLRNRPKDKDKMKACYRRSMSMNDLVQSMV
1450 1460 1470 1480 1490 1500
1480 1490 1500 1510 1520 1530
pF1KE3 LAGQWTGSTENLEVPDDISTGKRRKELGAMAFSTTAINFSTVNSSAGFRSKQLVNNKDTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAGQWTGSTENLEVPDDISTGKRRKELGAMAFSTTAINFSTVNSSAGFRSKQLVNNKDTT
1510 1520 1530 1540 1550 1560
1540 1550 1560 1570 1580 1590
pF1KE3 SFEDISPQGVSDDSSTGSRVHASRPASLDSGRTSTSNSNNNASLHEVKAGAVNNQSRPQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SFEDISPQGVSDDSSTGSRVHASRPASLDSGRTSTSNSNNNASLHEVKAGAVNNQSRPQS
1570 1580 1590 1600 1610 1620
1600 1610 1620 1630 1640 1650
pF1KE3 HSSGEFSLLHDHEAWSSSGSSPIQYLKRQTRSSPVLQHKISETLESRHHKIKTGSPGSEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HSSGEFSLLHDHEAWSSSGSSPIQYLKRQTRSSPVLQHKISETLESRHHKIKTGSPGSEV
1630 1640 1650 1660 1670 1680
1660 1670 1680 1690 1700 1710
pF1KE3 VTLQQFLEESNKLTSVQIKSSSQENLLDEVMKSLSVSSDFLGKDKPVSCGLARSVSGKTP
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VTLQQFLEESNKLTSVQIKSSSQENLLDEVMKSLSVSSDFLGKDKPVSCGLA--------
1690 1700 1710 1720 1730
1720 1730 1740 1750 1760 1770
pF1KE3 GDFYDRRTTKPEFLRPGPRKTEDTYFISSAGKPTPGTQGKIKLVKESSLSRQSKDSNPYA
XP_016 ------------------------------------------------------------
1780 1790 1800 1810 1820 1830
pF1KE3 TLPRASSVISTAEGTTRRTSIHDFLTKDSRLPISVDSPPAAADSNTTAASNVDKVQESRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ------SVISTAEGTTRRTSIHDFLTKDSRLPISVDSPPAAADSNTTAASNVDKVQESRN
1740 1750 1760 1770 1780
1840
pF1KE3 SKSRSREQQSS
:::::::::::
XP_016 SKSRSREQQSS
1790
>>XP_011531267 (OMIM: 260565,609736) PREDICTED: girdin i (1871 aa)
initn: 9111 init1: 9111 opt: 9111 Z-score: 3170.5 bits: 599.9 E(85289): 7.4e-170
Smith-Waterman score: 11460; 98.5% identity (98.5% similar) in 1871 aa overlap (1-1843:1-1871)
10 20 30 40 50 60
pF1KE3 MENEIFTPLLEQFMTSPLVTWVKTFGPLAAGNGTNLDEYVALVDGVFLNQVMLQINPKLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MENEIFTPLLEQFMTSPLVTWVKTFGPLAAGNGTNLDEYVALVDGVFLNQVMLQINPKLE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 SQRVNKKVNNDASLRMHNLSILVRQIKFYYQETLQQLIMMSLPNVLIIGKNPFSEQGTEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SQRVNKKVNNDASLRMHNLSILVRQIKFYYQETLQQLIMMSLPNVLIIGKNPFSEQGTEE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 VKKLLLLLLGCAVQCQKKEEFIERIQGLDFDTKAAVAAHIQEVTHNQENVFDLQWMEVTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VKKLLLLLLGCAVQCQKKEEFIERIQGLDFDTKAAVAAHIQEVTHNQENVFDLQWMEVTD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 MSQEDIEPLLKNMALHLKRLIDERDEHSETIIELSEERDGLHFLPHASSSAQSPCGSPGM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSQEDIEPLLKNMALHLKRLIDERDEHSETIIELSEERDGLHFLPHASSSAQSPCGSPGM
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 KRTESRQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KRTESRQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 DARSARMYRDELDALREKAVRVDKLESEVSRYKERLHDIEFYKARVEELKEDNQVLLETK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DARSARMYRDELDALREKAVRVDKLESEVSRYKERLHDIEFYKARVEELKEDNQVLLETK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 TMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQK
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 QSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELR
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 TTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEK
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 TIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETS
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 SKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEKIEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEKIEA
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 LEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKM
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 AQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQ
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE3 QLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKR
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE3 LRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATID
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE3 IKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDSRYKLLESK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDSRYKLLESK
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE3 LESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQSS
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE3 PPISGEDNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPISGEDNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQ
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE3 AQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENE
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE3 SVIKEREDLKSLYDSLIKDHEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHRDLED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SVIKEREDLKSLYDSLIKDHEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHRDLED
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE3 RYNQLLKQKGQLEDLEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDRLNHTYSQLLKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RYNQLLKQKGQLEDLEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDRLNHTYSQLLKE
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE3 TEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKGNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKGNL
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE3 EEENRHLLDQIQTLMLQNRTLLEQNMESKDLFHVEQRQYIDKLNELRRQKEKLEEKIMDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEENRHLLDQIQTLMLQNRTLLEQNMESKDLFHVEQRQYIDKLNELRRQKEKLEEKIMDQ
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KE3 YKFYDPSPPRRRGNWITLKMRKLIKSKKDINRERQKSLTLTPTRSDSSEGFLQLPHQDSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YKFYDPSPPRRRGNWITLKMRKLIKSKKDINRERQKSLTLTPTRSDSSEGFLQLPHQDSQ
1390 1400 1410 1420 1430 1440
1450 1460 1470
pF1KE3 DSSSVGSNSLEDGQTLGTKKSS----------------------------TMNDLVQSMV
:::::::::::::::::::::: .:::::::::
XP_011 DSSSVGSNSLEDGQTLGTKKSSMVALKRLPFLRNRPKDKDKMKACYRRSMSMNDLVQSMV
1450 1460 1470 1480 1490 1500
1480 1490 1500 1510 1520 1530
pF1KE3 LAGQWTGSTENLEVPDDISTGKRRKELGAMAFSTTAINFSTVNSSAGFRSKQLVNNKDTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LAGQWTGSTENLEVPDDISTGKRRKELGAMAFSTTAINFSTVNSSAGFRSKQLVNNKDTT
1510 1520 1530 1540 1550 1560
1540 1550 1560 1570 1580 1590
pF1KE3 SFEDISPQGVSDDSSTGSRVHASRPASLDSGRTSTSNSNNNASLHEVKAGAVNNQSRPQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SFEDISPQGVSDDSSTGSRVHASRPASLDSGRTSTSNSNNNASLHEVKAGAVNNQSRPQS
1570 1580 1590 1600 1610 1620
1600 1610 1620 1630 1640 1650
pF1KE3 HSSGEFSLLHDHEAWSSSGSSPIQYLKRQTRSSPVLQHKISETLESRHHKIKTGSPGSEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HSSGEFSLLHDHEAWSSSGSSPIQYLKRQTRSSPVLQHKISETLESRHHKIKTGSPGSEV
1630 1640 1650 1660 1670 1680
1660 1670 1680 1690 1700 1710
pF1KE3 VTLQQFLEESNKLTSVQIKSSSQENLLDEVMKSLSVSSDFLGKDKPVSCGLARSVSGKTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VTLQQFLEESNKLTSVQIKSSSQENLLDEVMKSLSVSSDFLGKDKPVSCGLARSVSGKTP
1690 1700 1710 1720 1730 1740
1720 1730 1740 1750 1760 1770
pF1KE3 GDFYDRRTTKPEFLRPGPRKTEDTYFISSAGKPTPGTQGKIKLVKESSLSRQSKDSNPYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GDFYDRRTTKPEFLRPGPRKTEDTYFISSAGKPTPGTQGKIKLVKESSLSRQSKDSNPYA
1750 1760 1770 1780 1790 1800
1780 1790 1800 1810 1820 1830
pF1KE3 TLPRASSVISTAEGTTRRTSIHDFLTKDSRLPISVDSPPAAADSNTTAASNVDKVQESRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TLPRASSVISTAEGTTRRTSIHDFLTKDSRLPISVDSPPAAADSNTTAASNVDKVQESRN
1810 1820 1830 1840 1850 1860
1840
pF1KE3 SKSRSREQQSS
:::::::::::
XP_011 SKSRSREQQSS
1870
>>XP_011531268 (OMIM: 260565,609736) PREDICTED: girdin i (1871 aa)
initn: 9111 init1: 9111 opt: 9111 Z-score: 3170.5 bits: 599.9 E(85289): 7.4e-170
Smith-Waterman score: 11460; 98.5% identity (98.5% similar) in 1871 aa overlap (1-1843:1-1871)
10 20 30 40 50 60
pF1KE3 MENEIFTPLLEQFMTSPLVTWVKTFGPLAAGNGTNLDEYVALVDGVFLNQVMLQINPKLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MENEIFTPLLEQFMTSPLVTWVKTFGPLAAGNGTNLDEYVALVDGVFLNQVMLQINPKLE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 SQRVNKKVNNDASLRMHNLSILVRQIKFYYQETLQQLIMMSLPNVLIIGKNPFSEQGTEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SQRVNKKVNNDASLRMHNLSILVRQIKFYYQETLQQLIMMSLPNVLIIGKNPFSEQGTEE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 VKKLLLLLLGCAVQCQKKEEFIERIQGLDFDTKAAVAAHIQEVTHNQENVFDLQWMEVTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VKKLLLLLLGCAVQCQKKEEFIERIQGLDFDTKAAVAAHIQEVTHNQENVFDLQWMEVTD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 MSQEDIEPLLKNMALHLKRLIDERDEHSETIIELSEERDGLHFLPHASSSAQSPCGSPGM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSQEDIEPLLKNMALHLKRLIDERDEHSETIIELSEERDGLHFLPHASSSAQSPCGSPGM
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 KRTESRQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KRTESRQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 DARSARMYRDELDALREKAVRVDKLESEVSRYKERLHDIEFYKARVEELKEDNQVLLETK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DARSARMYRDELDALREKAVRVDKLESEVSRYKERLHDIEFYKARVEELKEDNQVLLETK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 TMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQK
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 QSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELR
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 TTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEK
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 TIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETS
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 SKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEKIEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEKIEA
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 LEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKM
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 AQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQ
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE3 QLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKR
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE3 LRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATID
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE3 IKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDSRYKLLESK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDSRYKLLESK
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE3 LESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQSS
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE3 PPISGEDNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPISGEDNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQ
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE3 AQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENE
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE3 SVIKEREDLKSLYDSLIKDHEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHRDLED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SVIKEREDLKSLYDSLIKDHEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHRDLED
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE3 RYNQLLKQKGQLEDLEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDRLNHTYSQLLKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RYNQLLKQKGQLEDLEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDRLNHTYSQLLKE
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE3 TEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKGNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKGNL
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE3 EEENRHLLDQIQTLMLQNRTLLEQNMESKDLFHVEQRQYIDKLNELRRQKEKLEEKIMDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEENRHLLDQIQTLMLQNRTLLEQNMESKDLFHVEQRQYIDKLNELRRQKEKLEEKIMDQ
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KE3 YKFYDPSPPRRRGNWITLKMRKLIKSKKDINRERQKSLTLTPTRSDSSEGFLQLPHQDSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YKFYDPSPPRRRGNWITLKMRKLIKSKKDINRERQKSLTLTPTRSDSSEGFLQLPHQDSQ
1390 1400 1410 1420 1430 1440
1450 1460 1470
pF1KE3 DSSSVGSNSLEDGQTLGTKKSS----------------------------TMNDLVQSMV
:::::::::::::::::::::: .:::::::::
XP_011 DSSSVGSNSLEDGQTLGTKKSSMVALKRLPFLRNRPKDKDKMKACYRRSMSMNDLVQSMV
1450 1460 1470 1480 1490 1500
1480 1490 1500 1510 1520 1530
pF1KE3 LAGQWTGSTENLEVPDDISTGKRRKELGAMAFSTTAINFSTVNSSAGFRSKQLVNNKDTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LAGQWTGSTENLEVPDDISTGKRRKELGAMAFSTTAINFSTVNSSAGFRSKQLVNNKDTT
1510 1520 1530 1540 1550 1560
1540 1550 1560 1570 1580 1590
pF1KE3 SFEDISPQGVSDDSSTGSRVHASRPASLDSGRTSTSNSNNNASLHEVKAGAVNNQSRPQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SFEDISPQGVSDDSSTGSRVHASRPASLDSGRTSTSNSNNNASLHEVKAGAVNNQSRPQS
1570 1580 1590 1600 1610 1620
1600 1610 1620 1630 1640 1650
pF1KE3 HSSGEFSLLHDHEAWSSSGSSPIQYLKRQTRSSPVLQHKISETLESRHHKIKTGSPGSEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HSSGEFSLLHDHEAWSSSGSSPIQYLKRQTRSSPVLQHKISETLESRHHKIKTGSPGSEV
1630 1640 1650 1660 1670 1680
1660 1670 1680 1690 1700 1710
pF1KE3 VTLQQFLEESNKLTSVQIKSSSQENLLDEVMKSLSVSSDFLGKDKPVSCGLARSVSGKTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VTLQQFLEESNKLTSVQIKSSSQENLLDEVMKSLSVSSDFLGKDKPVSCGLARSVSGKTP
1690 1700 1710 1720 1730 1740
1720 1730 1740 1750 1760 1770
pF1KE3 GDFYDRRTTKPEFLRPGPRKTEDTYFISSAGKPTPGTQGKIKLVKESSLSRQSKDSNPYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GDFYDRRTTKPEFLRPGPRKTEDTYFISSAGKPTPGTQGKIKLVKESSLSRQSKDSNPYA
1750 1760 1770 1780 1790 1800
1780 1790 1800 1810 1820 1830
pF1KE3 TLPRASSVISTAEGTTRRTSIHDFLTKDSRLPISVDSPPAAADSNTTAASNVDKVQESRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TLPRASSVISTAEGTTRRTSIHDFLTKDSRLPISVDSPPAAADSNTTAASNVDKVQESRN
1810 1820 1830 1840 1850 1860
1840
pF1KE3 SKSRSREQQSS
:::::::::::
XP_011 SKSRSREQQSS
1870
1843 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 03:25:16 2016 done: Tue Nov 8 03:25:20 2016
Total Scan time: 21.910 Total Display time: 1.450
Function used was FASTA [36.3.4 Apr, 2011]