Result of FASTA (omim) for
pFN21AE3476
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3476, 1551 aa
1>>>pF1KE3476 1551 - 1551 aa - 1551 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 13.4702+/-0.000557; mu= -13.2572+/- 0.034
mean_var=816.7588+/-172.656, 0's: 0 Z-trim(120.7): 1294 B-trim: 0 in 0/59
Lambda= 0.044877
statistics sampled from 34836 (36329) to 34836 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.736), E-opt: 0.2 (0.426), width: 16
Scan time: 22.450
The best scores are: opt bits E(85289)
NP_059995 (OMIM: 613991) serine/threonine-protein (1551) 10387 690.2 3.4e-197
XP_016873487 (OMIM: 613991) PREDICTED: serine/thre (1081) 5808 393.5 4.9e-108
XP_011543463 (OMIM: 613991) PREDICTED: serine/thre (1135) 5808 393.6 5e-108
XP_016873486 (OMIM: 613991) PREDICTED: serine/thre (1139) 5808 393.6 5e-108
XP_011543461 (OMIM: 613991) PREDICTED: serine/thre (1481) 5808 393.7 5.9e-108
XP_011543460 (OMIM: 613991) PREDICTED: serine/thre (1495) 5808 393.7 5.9e-108
XP_011543459 (OMIM: 613991) PREDICTED: serine/thre (1530) 5808 393.7 6e-108
XP_011543457 (OMIM: 613991) PREDICTED: serine/thre (1569) 5808 393.8 6.1e-108
XP_016873485 (OMIM: 613991) PREDICTED: serine/thre (1568) 5790 392.6 1.4e-107
XP_011543462 (OMIM: 613991) PREDICTED: serine/thre (1471) 5168 352.3 1.7e-95
XP_011543458 (OMIM: 613991) PREDICTED: serine/thre (1562) 4665 319.7 1.2e-85
XP_016873488 (OMIM: 613991) PREDICTED: serine/thre ( 865) 4594 314.8 1.9e-84
XP_016858071 (OMIM: 603412) PREDICTED: serine/thre (1589) 2148 156.8 1.3e-36
NP_055641 (OMIM: 603412) serine/threonine-protein (1638) 2148 156.8 1.3e-36
NP_003598 (OMIM: 603412) serine/threonine-protein (1719) 2148 156.8 1.4e-36
XP_005273381 (OMIM: 603412) PREDICTED: serine/thre (1732) 2148 156.8 1.4e-36
XP_005273379 (OMIM: 603412) PREDICTED: serine/thre (1754) 2148 156.9 1.4e-36
XP_011542611 (OMIM: 603412) PREDICTED: serine/thre (1764) 2148 156.9 1.4e-36
XP_016858067 (OMIM: 603412) PREDICTED: serine/thre (1767) 2148 156.9 1.4e-36
XP_005273378 (OMIM: 603412) PREDICTED: serine/thre (1781) 2148 156.9 1.4e-36
XP_011542610 (OMIM: 603412) PREDICTED: serine/thre (1783) 2148 156.9 1.4e-36
XP_005273377 (OMIM: 603412) PREDICTED: serine/thre (1794) 2148 156.9 1.4e-36
XP_006711898 (OMIM: 603412) PREDICTED: serine/thre (1797) 2148 156.9 1.4e-36
XP_011542609 (OMIM: 603412) PREDICTED: serine/thre (1810) 2148 156.9 1.4e-36
XP_006711897 (OMIM: 603412) PREDICTED: serine/thre (1816) 2148 156.9 1.4e-36
XP_005273375 (OMIM: 603412) PREDICTED: serine/thre (1829) 2148 156.9 1.4e-36
XP_005273374 (OMIM: 603412) PREDICTED: serine/thre (1832) 2148 156.9 1.4e-36
XP_011542608 (OMIM: 603412) PREDICTED: serine/thre (1845) 2148 156.9 1.4e-36
XP_011535689 (OMIM: 614062) PREDICTED: serine/thre (1460) 2021 148.5 3.8e-34
XP_005268287 (OMIM: 614062) PREDICTED: serine/thre (1490) 2021 148.5 3.8e-34
XP_005268286 (OMIM: 614062) PREDICTED: serine/thre (1685) 2021 148.6 4.1e-34
XP_005268285 (OMIM: 614062) PREDICTED: serine/thre (1702) 2021 148.6 4.1e-34
NP_006026 (OMIM: 614062) serine/threonine-protein (1711) 2021 148.6 4.1e-34
XP_005268284 (OMIM: 614062) PREDICTED: serine/thre (1728) 2021 148.6 4.2e-34
XP_016858070 (OMIM: 603412) PREDICTED: serine/thre (1712) 1798 134.2 9.2e-30
XP_016858068 (OMIM: 603412) PREDICTED: serine/thre (1741) 1798 134.2 9.3e-30
XP_016858069 (OMIM: 603412) PREDICTED: serine/thre (1741) 1798 134.2 9.3e-30
NP_001275695 (OMIM: 160900,605377) myotonin-protei ( 530) 1688 126.4 6.3e-28
NP_001075029 (OMIM: 160900,605377) myotonin-protei ( 624) 1688 126.5 6.9e-28
NP_001075031 (OMIM: 160900,605377) myotonin-protei ( 625) 1688 126.5 7e-28
NP_004400 (OMIM: 160900,605377) myotonin-protein k ( 629) 1671 125.4 1.5e-27
NP_001275693 (OMIM: 160900,605377) myotonin-protei ( 655) 1541 117.0 5.2e-25
NP_001075032 (OMIM: 160900,605377) myotonin-protei ( 639) 1535 116.6 6.8e-25
NP_005397 (OMIM: 601702) rho-associated protein ki (1354) 1407 108.7 3.3e-22
NP_004841 (OMIM: 604002) rho-associated protein ki (1388) 1399 108.2 4.8e-22
XP_016860867 (OMIM: 604002) PREDICTED: rho-associa (1404) 1399 108.2 4.9e-22
XP_005246247 (OMIM: 604002) PREDICTED: rho-associa (1417) 1399 108.2 4.9e-22
NP_001275694 (OMIM: 160900,605377) myotonin-protei ( 541) 1359 105.1 1.6e-21
XP_011536090 (OMIM: 605629,617090) PREDICTED: citr (2011) 1364 106.2 2.9e-21
XP_011536089 (OMIM: 605629,617090) PREDICTED: citr (2012) 1364 106.2 2.9e-21
>>NP_059995 (OMIM: 613991) serine/threonine-protein kina (1551 aa)
initn: 10387 init1: 10387 opt: 10387 Z-score: 3661.2 bits: 690.2 E(85289): 3.4e-197
Smith-Waterman score: 10387; 100.0% identity (100.0% similar) in 1551 aa overlap (1-1551:1-1551)
10 20 30 40 50 60
pF1KE3 MERRLRALEQLARGEAGGCPGLDGLLDLLLALHHELSSGPLRRERSVAQFLSWASPFVSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_059 MERRLRALEQLARGEAGGCPGLDGLLDLLLALHHELSSGPLRRERSVAQFLSWASPFVSK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 VKELRLQRDDFEILKVIGRGAFGEVTVVRQRDTGQIFAMKMLHKWEMLKRAETACFREER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_059 VKELRLQRDDFEILKVIGRGAFGEVTVVRQRDTGQIFAMKMLHKWEMLKRAETACFREER
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 DVLVKGDSRWVTTLHYAFQDEEYLYLVMDYYAGGDLLTLLSRFEDRLPPELAQFYLAEMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_059 DVLVKGDSRWVTTLHYAFQDEEYLYLVMDYYAGGDLLTLLSRFEDRLPPELAQFYLAEMV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 LAIHSLHQLGYVHRDVKPDNVLLDVNGHIRLADFGSCLRLNTNGMVDSSVAVGTPDYISP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_059 LAIHSLHQLGYVHRDVKPDNVLLDVNGHIRLADFGSCLRLNTNGMVDSSVAVGTPDYISP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 EILQAMEEGKGHYGPQCDWWSLGVCAYELLFGETPFYAESLVETYGKIMNHEDHLQFPPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_059 EILQAMEEGKGHYGPQCDWWSLGVCAYELLFGETPFYAESLVETYGKIMNHEDHLQFPPD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 VPDVPASAQDLIRQLLCRQEERLGRGGLDDFRNHPFFEGVDWERLASSTAPYIPELRGPM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_059 VPDVPASAQDLIRQLLCRQEERLGRGGLDDFRNHPFFEGVDWERLASSTAPYIPELRGPM
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 DTSNFDVDDDTLNHPGTLPPPSHGAFSGHHLPFVGFTYTSGSHSPESSSEAWAALERKLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_059 DTSNFDVDDDTLNHPGTLPPPSHGAFSGHHLPFVGFTYTSGSHSPESSSEAWAALERKLQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 CLEQEKVELSRKHQEALHAPTDHRELEQLRKEVQTLRDRLPEMLRDKASLSQTDGPPAGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_059 CLEQEKVELSRKHQEALHAPTDHRELEQLRKEVQTLRDRLPEMLRDKASLSQTDGPPAGS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 PGQDSDLRQELDRLHRELAEGRAGLQAQEQELCRAQGQQEELLQRLQEAQEREAATASQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_059 PGQDSDLRQELDRLHRELAEGRAGLQAQEQELCRAQGQQEELLQRLQEAQEREAATASQT
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 RALSSQLEEARAAQRELEAQVSSLSRQVTQLQGQWEQRLEESSQAKTIHTASETNGMGPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_059 RALSSQLEEARAAQRELEAQVSSLSRQVTQLQGQWEQRLEESSQAKTIHTASETNGMGPP
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 EGGPQEAQLRKEVAALREQLEQAHSHRPSGKEEALCQLQEENRRLSREQERLEAELAQEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_059 EGGPQEAQLRKEVAALREQLEQAHSHRPSGKEEALCQLQEENRRLSREQERLEAELAQEQ
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 ESKQRLEGERRETESNWEAQLADILSWVNDEKVSRGYLQALATKMAEELESLRNVGTQTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_059 ESKQRLEGERRETESNWEAQLADILSWVNDEKVSRGYLQALATKMAEELESLRNVGTQTL
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 PARPLDHQWKARRLQKMEASARLELQSALEAEIRAKQGLQERLTQVQEAQLQAERRLQEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_059 PARPLDHQWKARRLQKMEASARLELQSALEAEIRAKQGLQERLTQVQEAQLQAERRLQEA
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE3 EKQSQALQQELAMLREELRARGPVDTKPSNSLIPFLSFRSSEKDSAKDPGISGEATRHGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_059 EKQSQALQQELAMLREELRARGPVDTKPSNSLIPFLSFRSSEKDSAKDPGISGEATRHGG
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE3 EPDLRPEGRRSLRMGAVFPRAPTANTASTEGLPAKPGSHTLRPRSFPSPTKCLRCTSLML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_059 EPDLRPEGRRSLRMGAVFPRAPTANTASTEGLPAKPGSHTLRPRSFPSPTKCLRCTSLML
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE3 GLGRQGLGCDACGYFCHTTCAPQAPPCPVPPDLLRTALGVHPETGTGTAYEGFLSVPRPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_059 GLGRQGLGCDACGYFCHTTCAPQAPPCPVPPDLLRTALGVHPETGTGTAYEGFLSVPRPS
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE3 GVRRGWQRVFAALSDSRLLLFDAPDLRLSPPSGALLQVLDLRDPQFSATPVLASDVIHAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_059 GVRRGWQRVFAALSDSRLLLFDAPDLRLSPPSGALLQVLDLRDPQFSATPVLASDVIHAQ
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE3 SRDLPRIFRVTTSQLAVPPTTCTVLLLAESEGERERWLQVLGELQRLLLDARPRPRPVYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_059 SRDLPRIFRVTTSQLAVPPTTCTVLLLAESEGERERWLQVLGELQRLLLDARPRPRPVYT
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE3 LKEAYDNGLPLLPHTLCAAILDQDRLALGTEEGLFVIHLRSNDIFQVGECRRVQQLTLSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_059 LKEAYDNGLPLLPHTLCAAILDQDRLALGTEEGLFVIHLRSNDIFQVGECRRVQQLTLSP
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE3 SAGLLVVLCGRGPSVRLFALAELENIEVAGAKIPESRGCQVLAAGSILQARTPVLCVAVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_059 SAGLLVVLCGRGPSVRLFALAELENIEVAGAKIPESRGCQVLAAGSILQARTPVLCVAVK
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE3 RQVLCYQLGPGPGPWQRRIRELQAPATVQSLGLLGDRLCVGAAGGFALYPLLNEAAPLAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_059 RQVLCYQLGPGPGPWQRRIRELQAPATVQSLGLLGDRLCVGAAGGFALYPLLNEAAPLAL
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE3 GAGLVPEELPPSRGGLGEALGAVELSLSEFLLLFTTAGIYVDGAGRKSRGHELLWPAAPM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_059 GAGLVPEELPPSRGGLGEALGAVELSLSEFLLLFTTAGIYVDGAGRKSRGHELLWPAAPM
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE3 GWGYAAPYLTVFSENSIDVFDVRRAEWVQTVPLKKVRPLNPEGSLFLYGTEKVRLTYLRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_059 GWGYAAPYLTVFSENSIDVFDVRRAEWVQTVPLKKVRPLNPEGSLFLYGTEKVRLTYLRN
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KE3 QLAEKDEFDIPDLTDNSRRQLFRTKSKRRFFFRVSEEQQKQQRREMLKDPFVRSKLISPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_059 QLAEKDEFDIPDLTDNSRRQLFRTKSKRRFFFRVSEEQQKQQRREMLKDPFVRSKLISPP
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KE3 TNFNHLVHVGPANGRPGARDKSPAPEEKGRVARGSGPQRPHSFSEALRRPASMGSEGLGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_059 TNFNHLVHVGPANGRPGARDKSPAPEEKGRVARGSGPQRPHSFSEALRRPASMGSEGLGG
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550
pF1KE3 DADPMKRKPWTSLSSESVSCPQGSLSPATSLMQVSERPRSLPLSPELESSP
:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_059 DADPMKRKPWTSLSSESVSCPQGSLSPATSLMQVSERPRSLPLSPELESSP
1510 1520 1530 1540 1550
>>XP_016873487 (OMIM: 613991) PREDICTED: serine/threonin (1081 aa)
initn: 5808 init1: 5808 opt: 5808 Z-score: 2060.6 bits: 393.5 E(85289): 4.9e-108
Smith-Waterman score: 6855; 97.6% identity (97.8% similar) in 1057 aa overlap (1-1039:1-1056)
10 20 30 40 50 60
pF1KE3 MERRLRALEQLARGEAGGCPGLDGLLDLLLALHHELSSGPLRRERSVAQFLSWASPFVSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MERRLRALEQLARGEAGGCPGLDGLLDLLLALHHELSSGPLRRERSVAQFLSWASPFVSK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 VKELRLQRDDFEILKVIGRGAFGEVTVVRQRDTGQIFAMKMLHKWEMLKRAETACFREER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VKELRLQRDDFEILKVIGRGAFGEVTVVRQRDTGQIFAMKMLHKWEMLKRAETACFREER
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 DVLVKGDSRWVTTLHYAFQDEEYLYLVMDYYAGGDLLTLLSRFEDRLPPELAQFYLAEMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DVLVKGDSRWVTTLHYAFQDEEYLYLVMDYYAGGDLLTLLSRFEDRLPPELAQFYLAEMV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 LAIHSLHQLGYVHRDVKPDNVLLDVNGHIRLADFGSCLRLNTNGMVDSSVAVGTPDYISP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAIHSLHQLGYVHRDVKPDNVLLDVNGHIRLADFGSCLRLNTNGMVDSSVAVGTPDYISP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 EILQAMEEGKGHYGPQCDWWSLGVCAYELLFGETPFYAESLVETYGKIMNHEDHLQFPPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EILQAMEEGKGHYGPQCDWWSLGVCAYELLFGETPFYAESLVETYGKIMNHEDHLQFPPD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 VPDVPASAQDLIRQLLCRQEERLGRGGLDDFRNHPFFEGVDWERLASSTAPYIPELRGPM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VPDVPASAQDLIRQLLCRQEERLGRGGLDDFRNHPFFEGVDWERLASSTAPYIPELRGPM
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 DTSNFDVDDDTLNHPGTLPPPSHGAFSGHHLPFVGFTYTSGSHSPESSSEAWAALERKLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DTSNFDVDDDTLNHPGTLPPPSHGAFSGHHLPFVGFTYTSGSHSPESSSEAWAALERKLQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 CLEQEKVELSRKHQEALHAPTDHRELEQLRKEVQTLRDRLPEMLRDKASLSQTDGPPAGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CLEQEKVELSRKHQEALHAPTDHRELEQLRKEVQTLRDRLPEMLRDKASLSQTDGPPAGS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 PGQDSDLRQELDRLHRELAEGRAGLQAQEQELCRAQGQQEELLQRLQEAQEREAATASQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGQDSDLRQELDRLHRELAEGRAGLQAQEQELCRAQGQQEELLQRLQEAQEREAATASQT
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 RALSSQLEEARAAQRELEAQVSSLSRQVTQLQGQWEQRLEESSQAKTIHTASETNGMGPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RALSSQLEEARAAQRELEAQVSSLSRQVTQLQGQWEQRLEESSQAKTIHTASETNGMGPP
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 EGGPQEAQLRKEVAALREQLEQAHSHRPSGKEEALCQLQEENRRLSREQERLEAELAQEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EGGPQEAQLRKEVAALREQLEQAHSHRPSGKEEALCQLQEENRRLSREQERLEAELAQEQ
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 ESKQRLEGERRETESNWEAQLADILSWVNDEKVSRGYLQALATKMAEELESLRNVGTQTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESKQRLEGERRETESNWEAQLADILSWVNDEKVSRGYLQALATKMAEELESLRNVGTQTL
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 PARPLDHQWKARRLQKMEASARLELQSALEAEIRAKQGLQERLTQVQEAQLQAERRLQEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PARPLDHQWKARRLQKMEASARLELQSALEAEIRAKQGLQERLTQVQEAQLQAERRLQEA
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE3 EKQSQALQQELAMLREELRARGPVDTKPSNSLIPFLSFRSSEKDSAKDPGISGEATRHGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKQSQALQQELAMLREELRARGPVDTKPSNSLIPFLSFRSSEKDSAKDPGISGEATRHGG
790 800 810 820 830 840
850 860 870 880
pF1KE3 EPDLRPEGRRSLRMGAVFPRAPTANTASTEGLPAK------------------PGSHTLR
::::::::::::::::::::::::::::::::::: :::::::
XP_016 EPDLRPEGRRSLRMGAVFPRAPTANTASTEGLPAKGWGMGPWEALGNGCPPPQPGSHTLR
850 860 870 880 890 900
890 900 910 920 930 940
pF1KE3 PRSFPSPTKCLRCTSLMLGLGRQGLGCDACGYFCHTTCAPQAPPCPVPPDLLRTALGVHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PRSFPSPTKCLRCTSLMLGLGRQGLGCDACGYFCHTTCAPQAPPCPVPPDLLRTALGVHP
910 920 930 940 950 960
950 960 970 980 990 1000
pF1KE3 ETGTGTAYEGFLSVPRPSGVRRGWQRVFAALSDSRLLLFDAPDLRLSPPSGALLQVLDLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ETGTGTAYEGFLSVPRPSGVRRGWQRVFAALSDSRLLLFDAPDLRLSPPSGALLQVLDLR
970 980 990 1000 1010 1020
1010 1020 1030 1040 1050 1060
pF1KE3 DPQFSATPVLASDVIHAQSRDLPRIFRVTTSQLAVPPTTCTVLLLAESEGERERWLQVLG
::::::::::::::::::::::::::: : .: . :
XP_016 DPQFSATPVLASDVIHAQSRDLPRIFR-TRIDLRLAPRRGSLSSICAATTSSRWGSAGAC
1030 1040 1050 1060 1070
1070 1080 1090 1100 1110 1120
pF1KE3 ELQRLLLDARPRPRPVYTLKEAYDNGLPLLPHTLCAAILDQDRLALGTEEGLFVIHLRSN
XP_016 SS
1080
>>XP_011543463 (OMIM: 613991) PREDICTED: serine/threonin (1135 aa)
initn: 7369 init1: 5808 opt: 5808 Z-score: 2060.4 bits: 393.6 E(85289): 5e-108
Smith-Waterman score: 7337; 98.3% identity (98.4% similar) in 1121 aa overlap (1-1103:1-1121)
10 20 30 40 50 60
pF1KE3 MERRLRALEQLARGEAGGCPGLDGLLDLLLALHHELSSGPLRRERSVAQFLSWASPFVSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MERRLRALEQLARGEAGGCPGLDGLLDLLLALHHELSSGPLRRERSVAQFLSWASPFVSK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 VKELRLQRDDFEILKVIGRGAFGEVTVVRQRDTGQIFAMKMLHKWEMLKRAETACFREER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VKELRLQRDDFEILKVIGRGAFGEVTVVRQRDTGQIFAMKMLHKWEMLKRAETACFREER
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 DVLVKGDSRWVTTLHYAFQDEEYLYLVMDYYAGGDLLTLLSRFEDRLPPELAQFYLAEMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DVLVKGDSRWVTTLHYAFQDEEYLYLVMDYYAGGDLLTLLSRFEDRLPPELAQFYLAEMV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 LAIHSLHQLGYVHRDVKPDNVLLDVNGHIRLADFGSCLRLNTNGMVDSSVAVGTPDYISP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LAIHSLHQLGYVHRDVKPDNVLLDVNGHIRLADFGSCLRLNTNGMVDSSVAVGTPDYISP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 EILQAMEEGKGHYGPQCDWWSLGVCAYELLFGETPFYAESLVETYGKIMNHEDHLQFPPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EILQAMEEGKGHYGPQCDWWSLGVCAYELLFGETPFYAESLVETYGKIMNHEDHLQFPPD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 VPDVPASAQDLIRQLLCRQEERLGRGGLDDFRNHPFFEGVDWERLASSTAPYIPELRGPM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VPDVPASAQDLIRQLLCRQEERLGRGGLDDFRNHPFFEGVDWERLASSTAPYIPELRGPM
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 DTSNFDVDDDTLNHPGTLPPPSHGAFSGHHLPFVGFTYTSGSHSPESSSEAWAALERKLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DTSNFDVDDDTLNHPGTLPPPSHGAFSGHHLPFVGFTYTSGSHSPESSSEAWAALERKLQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 CLEQEKVELSRKHQEALHAPTDHRELEQLRKEVQTLRDRLPEMLRDKASLSQTDGPPAGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CLEQEKVELSRKHQEALHAPTDHRELEQLRKEVQTLRDRLPEMLRDKASLSQTDGPPAGS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 PGQDSDLRQELDRLHRELAEGRAGLQAQEQELCRAQGQQEELLQRLQEAQEREAATASQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PGQDSDLRQELDRLHRELAEGRAGLQAQEQELCRAQGQQEELLQRLQEAQEREAATASQT
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 RALSSQLEEARAAQRELEAQVSSLSRQVTQLQGQWEQRLEESSQAKTIHTASETNGMGPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RALSSQLEEARAAQRELEAQVSSLSRQVTQLQGQWEQRLEESSQAKTIHTASETNGMGPP
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 EGGPQEAQLRKEVAALREQLEQAHSHRPSGKEEALCQLQEENRRLSREQERLEAELAQEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EGGPQEAQLRKEVAALREQLEQAHSHRPSGKEEALCQLQEENRRLSREQERLEAELAQEQ
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 ESKQRLEGERRETESNWEAQLADILSWVNDEKVSRGYLQALATKMAEELESLRNVGTQTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ESKQRLEGERRETESNWEAQLADILSWVNDEKVSRGYLQALATKMAEELESLRNVGTQTL
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 PARPLDHQWKARRLQKMEASARLELQSALEAEIRAKQGLQERLTQVQEAQLQAERRLQEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PARPLDHQWKARRLQKMEASARLELQSALEAEIRAKQGLQERLTQVQEAQLQAERRLQEA
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE3 EKQSQALQQELAMLREELRARGPVDTKPSNSLIPFLSFRSSEKDSAKDPGISGEATRHGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKQSQALQQELAMLREELRARGPVDTKPSNSLIPFLSFRSSEKDSAKDPGISGEATRHGG
790 800 810 820 830 840
850 860 870 880
pF1KE3 EPDLRPEGRRSLRMGAVFPRAPTANTASTEGLPAK------------------PGSHTLR
::::::::::::::::::::::::::::::::::: :::::::
XP_011 EPDLRPEGRRSLRMGAVFPRAPTANTASTEGLPAKGWGMGPWEALGNGCPPPQPGSHTLR
850 860 870 880 890 900
890 900 910 920 930 940
pF1KE3 PRSFPSPTKCLRCTSLMLGLGRQGLGCDACGYFCHTTCAPQAPPCPVPPDLLRTALGVHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PRSFPSPTKCLRCTSLMLGLGRQGLGCDACGYFCHTTCAPQAPPCPVPPDLLRTALGVHP
910 920 930 940 950 960
950 960 970 980 990 1000
pF1KE3 ETGTGTAYEGFLSVPRPSGVRRGWQRVFAALSDSRLLLFDAPDLRLSPPSGALLQVLDLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ETGTGTAYEGFLSVPRPSGVRRGWQRVFAALSDSRLLLFDAPDLRLSPPSGALLQVLDLR
970 980 990 1000 1010 1020
1010 1020 1030 1040 1050 1060
pF1KE3 DPQFSATPVLASDVIHAQSRDLPRIFRVTTSQLAVPPTTCTVLLLAESEGERERWLQVLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DPQFSATPVLASDVIHAQSRDLPRIFRVTTSQLAVPPTTCTVLLLAESEGERERWLQVLG
1030 1040 1050 1060 1070 1080
1070 1080 1090 1100 1110 1120
pF1KE3 ELQRLLLDARPRPRPVYTLKEAYDNGLPLLPHTLCAAILDQDRLALGTEEGLFVIHLRSN
::::::::::::::::::::::::::::::::::::::::.
XP_011 ELQRLLLDARPRPRPVYTLKEAYDNGLPLLPHTLCAAILDKQAQQGRWTAQSPCH
1090 1100 1110 1120 1130
1130 1140 1150 1160 1170 1180
pF1KE3 DIFQVGECRRVQQLTLSPSAGLLVVLCGRGPSVRLFALAELENIEVAGAKIPESRGCQVL
>>XP_016873486 (OMIM: 613991) PREDICTED: serine/threonin (1139 aa)
initn: 5808 init1: 5808 opt: 5808 Z-score: 2060.4 bits: 393.6 E(85289): 5e-108
Smith-Waterman score: 7327; 98.4% identity (98.4% similar) in 1119 aa overlap (1-1101:1-1119)
10 20 30 40 50 60
pF1KE3 MERRLRALEQLARGEAGGCPGLDGLLDLLLALHHELSSGPLRRERSVAQFLSWASPFVSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MERRLRALEQLARGEAGGCPGLDGLLDLLLALHHELSSGPLRRERSVAQFLSWASPFVSK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 VKELRLQRDDFEILKVIGRGAFGEVTVVRQRDTGQIFAMKMLHKWEMLKRAETACFREER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VKELRLQRDDFEILKVIGRGAFGEVTVVRQRDTGQIFAMKMLHKWEMLKRAETACFREER
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 DVLVKGDSRWVTTLHYAFQDEEYLYLVMDYYAGGDLLTLLSRFEDRLPPELAQFYLAEMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DVLVKGDSRWVTTLHYAFQDEEYLYLVMDYYAGGDLLTLLSRFEDRLPPELAQFYLAEMV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 LAIHSLHQLGYVHRDVKPDNVLLDVNGHIRLADFGSCLRLNTNGMVDSSVAVGTPDYISP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAIHSLHQLGYVHRDVKPDNVLLDVNGHIRLADFGSCLRLNTNGMVDSSVAVGTPDYISP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 EILQAMEEGKGHYGPQCDWWSLGVCAYELLFGETPFYAESLVETYGKIMNHEDHLQFPPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EILQAMEEGKGHYGPQCDWWSLGVCAYELLFGETPFYAESLVETYGKIMNHEDHLQFPPD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 VPDVPASAQDLIRQLLCRQEERLGRGGLDDFRNHPFFEGVDWERLASSTAPYIPELRGPM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VPDVPASAQDLIRQLLCRQEERLGRGGLDDFRNHPFFEGVDWERLASSTAPYIPELRGPM
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 DTSNFDVDDDTLNHPGTLPPPSHGAFSGHHLPFVGFTYTSGSHSPESSSEAWAALERKLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DTSNFDVDDDTLNHPGTLPPPSHGAFSGHHLPFVGFTYTSGSHSPESSSEAWAALERKLQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 CLEQEKVELSRKHQEALHAPTDHRELEQLRKEVQTLRDRLPEMLRDKASLSQTDGPPAGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CLEQEKVELSRKHQEALHAPTDHRELEQLRKEVQTLRDRLPEMLRDKASLSQTDGPPAGS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 PGQDSDLRQELDRLHRELAEGRAGLQAQEQELCRAQGQQEELLQRLQEAQEREAATASQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGQDSDLRQELDRLHRELAEGRAGLQAQEQELCRAQGQQEELLQRLQEAQEREAATASQT
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 RALSSQLEEARAAQRELEAQVSSLSRQVTQLQGQWEQRLEESSQAKTIHTASETNGMGPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RALSSQLEEARAAQRELEAQVSSLSRQVTQLQGQWEQRLEESSQAKTIHTASETNGMGPP
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 EGGPQEAQLRKEVAALREQLEQAHSHRPSGKEEALCQLQEENRRLSREQERLEAELAQEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EGGPQEAQLRKEVAALREQLEQAHSHRPSGKEEALCQLQEENRRLSREQERLEAELAQEQ
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 ESKQRLEGERRETESNWEAQLADILSWVNDEKVSRGYLQALATKMAEELESLRNVGTQTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESKQRLEGERRETESNWEAQLADILSWVNDEKVSRGYLQALATKMAEELESLRNVGTQTL
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 PARPLDHQWKARRLQKMEASARLELQSALEAEIRAKQGLQERLTQVQEAQLQAERRLQEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PARPLDHQWKARRLQKMEASARLELQSALEAEIRAKQGLQERLTQVQEAQLQAERRLQEA
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE3 EKQSQALQQELAMLREELRARGPVDTKPSNSLIPFLSFRSSEKDSAKDPGISGEATRHGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKQSQALQQELAMLREELRARGPVDTKPSNSLIPFLSFRSSEKDSAKDPGISGEATRHGG
790 800 810 820 830 840
850 860 870 880
pF1KE3 EPDLRPEGRRSLRMGAVFPRAPTANTASTEGLPAK------------------PGSHTLR
::::::::::::::::::::::::::::::::::: :::::::
XP_016 EPDLRPEGRRSLRMGAVFPRAPTANTASTEGLPAKGWGMGPWEALGNGCPPPQPGSHTLR
850 860 870 880 890 900
890 900 910 920 930 940
pF1KE3 PRSFPSPTKCLRCTSLMLGLGRQGLGCDACGYFCHTTCAPQAPPCPVPPDLLRTALGVHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PRSFPSPTKCLRCTSLMLGLGRQGLGCDACGYFCHTTCAPQAPPCPVPPDLLRTALGVHP
910 920 930 940 950 960
950 960 970 980 990 1000
pF1KE3 ETGTGTAYEGFLSVPRPSGVRRGWQRVFAALSDSRLLLFDAPDLRLSPPSGALLQVLDLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ETGTGTAYEGFLSVPRPSGVRRGWQRVFAALSDSRLLLFDAPDLRLSPPSGALLQVLDLR
970 980 990 1000 1010 1020
1010 1020 1030 1040 1050 1060
pF1KE3 DPQFSATPVLASDVIHAQSRDLPRIFRVTTSQLAVPPTTCTVLLLAESEGERERWLQVLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DPQFSATPVLASDVIHAQSRDLPRIFRVTTSQLAVPPTTCTVLLLAESEGERERWLQVLG
1030 1040 1050 1060 1070 1080
1070 1080 1090 1100 1110 1120
pF1KE3 ELQRLLLDARPRPRPVYTLKEAYDNGLPLLPHTLCAAILDQDRLALGTEEGLFVIHLRSN
:::::::::::::::::::::::::::::::::::::::
XP_016 ELQRLLLDARPRPRPVYTLKEAYDNGLPLLPHTLCAAILGTAGQVDCPISVSLSGTADL
1090 1100 1110 1120 1130
1130 1140 1150 1160 1170 1180
pF1KE3 DIFQVGECRRVQQLTLSPSAGLLVVLCGRGPSVRLFALAELENIEVAGAKIPESRGCQVL
>>XP_011543461 (OMIM: 613991) PREDICTED: serine/threonin (1481 aa)
initn: 5850 init1: 5808 opt: 5808 Z-score: 2059.1 bits: 393.7 E(85289): 5.9e-108
Smith-Waterman score: 9746; 98.8% identity (98.8% similar) in 1481 aa overlap (1-1463:1-1481)
10 20 30 40 50 60
pF1KE3 MERRLRALEQLARGEAGGCPGLDGLLDLLLALHHELSSGPLRRERSVAQFLSWASPFVSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MERRLRALEQLARGEAGGCPGLDGLLDLLLALHHELSSGPLRRERSVAQFLSWASPFVSK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 VKELRLQRDDFEILKVIGRGAFGEVTVVRQRDTGQIFAMKMLHKWEMLKRAETACFREER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VKELRLQRDDFEILKVIGRGAFGEVTVVRQRDTGQIFAMKMLHKWEMLKRAETACFREER
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 DVLVKGDSRWVTTLHYAFQDEEYLYLVMDYYAGGDLLTLLSRFEDRLPPELAQFYLAEMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DVLVKGDSRWVTTLHYAFQDEEYLYLVMDYYAGGDLLTLLSRFEDRLPPELAQFYLAEMV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 LAIHSLHQLGYVHRDVKPDNVLLDVNGHIRLADFGSCLRLNTNGMVDSSVAVGTPDYISP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LAIHSLHQLGYVHRDVKPDNVLLDVNGHIRLADFGSCLRLNTNGMVDSSVAVGTPDYISP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 EILQAMEEGKGHYGPQCDWWSLGVCAYELLFGETPFYAESLVETYGKIMNHEDHLQFPPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EILQAMEEGKGHYGPQCDWWSLGVCAYELLFGETPFYAESLVETYGKIMNHEDHLQFPPD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 VPDVPASAQDLIRQLLCRQEERLGRGGLDDFRNHPFFEGVDWERLASSTAPYIPELRGPM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VPDVPASAQDLIRQLLCRQEERLGRGGLDDFRNHPFFEGVDWERLASSTAPYIPELRGPM
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 DTSNFDVDDDTLNHPGTLPPPSHGAFSGHHLPFVGFTYTSGSHSPESSSEAWAALERKLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DTSNFDVDDDTLNHPGTLPPPSHGAFSGHHLPFVGFTYTSGSHSPESSSEAWAALERKLQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 CLEQEKVELSRKHQEALHAPTDHRELEQLRKEVQTLRDRLPEMLRDKASLSQTDGPPAGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CLEQEKVELSRKHQEALHAPTDHRELEQLRKEVQTLRDRLPEMLRDKASLSQTDGPPAGS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 PGQDSDLRQELDRLHRELAEGRAGLQAQEQELCRAQGQQEELLQRLQEAQEREAATASQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PGQDSDLRQELDRLHRELAEGRAGLQAQEQELCRAQGQQEELLQRLQEAQEREAATASQT
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 RALSSQLEEARAAQRELEAQVSSLSRQVTQLQGQWEQRLEESSQAKTIHTASETNGMGPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RALSSQLEEARAAQRELEAQVSSLSRQVTQLQGQWEQRLEESSQAKTIHTASETNGMGPP
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 EGGPQEAQLRKEVAALREQLEQAHSHRPSGKEEALCQLQEENRRLSREQERLEAELAQEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EGGPQEAQLRKEVAALREQLEQAHSHRPSGKEEALCQLQEENRRLSREQERLEAELAQEQ
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 ESKQRLEGERRETESNWEAQLADILSWVNDEKVSRGYLQALATKMAEELESLRNVGTQTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ESKQRLEGERRETESNWEAQLADILSWVNDEKVSRGYLQALATKMAEELESLRNVGTQTL
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 PARPLDHQWKARRLQKMEASARLELQSALEAEIRAKQGLQERLTQVQEAQLQAERRLQEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PARPLDHQWKARRLQKMEASARLELQSALEAEIRAKQGLQERLTQVQEAQLQAERRLQEA
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE3 EKQSQALQQELAMLREELRARGPVDTKPSNSLIPFLSFRSSEKDSAKDPGISGEATRHGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKQSQALQQELAMLREELRARGPVDTKPSNSLIPFLSFRSSEKDSAKDPGISGEATRHGG
790 800 810 820 830 840
850 860 870 880
pF1KE3 EPDLRPEGRRSLRMGAVFPRAPTANTASTEGLPAK------------------PGSHTLR
::::::::::::::::::::::::::::::::::: :::::::
XP_011 EPDLRPEGRRSLRMGAVFPRAPTANTASTEGLPAKGWGMGPWEALGNGCPPPQPGSHTLR
850 860 870 880 890 900
890 900 910 920 930 940
pF1KE3 PRSFPSPTKCLRCTSLMLGLGRQGLGCDACGYFCHTTCAPQAPPCPVPPDLLRTALGVHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PRSFPSPTKCLRCTSLMLGLGRQGLGCDACGYFCHTTCAPQAPPCPVPPDLLRTALGVHP
910 920 930 940 950 960
950 960 970 980 990 1000
pF1KE3 ETGTGTAYEGFLSVPRPSGVRRGWQRVFAALSDSRLLLFDAPDLRLSPPSGALLQVLDLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ETGTGTAYEGFLSVPRPSGVRRGWQRVFAALSDSRLLLFDAPDLRLSPPSGALLQVLDLR
970 980 990 1000 1010 1020
1010 1020 1030 1040 1050 1060
pF1KE3 DPQFSATPVLASDVIHAQSRDLPRIFRVTTSQLAVPPTTCTVLLLAESEGERERWLQVLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DPQFSATPVLASDVIHAQSRDLPRIFRVTTSQLAVPPTTCTVLLLAESEGERERWLQVLG
1030 1040 1050 1060 1070 1080
1070 1080 1090 1100 1110 1120
pF1KE3 ELQRLLLDARPRPRPVYTLKEAYDNGLPLLPHTLCAAILDQDRLALGTEEGLFVIHLRSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELQRLLLDARPRPRPVYTLKEAYDNGLPLLPHTLCAAILDQDRLALGTEEGLFVIHLRSN
1090 1100 1110 1120 1130 1140
1130 1140 1150 1160 1170 1180
pF1KE3 DIFQVGECRRVQQLTLSPSAGLLVVLCGRGPSVRLFALAELENIEVAGAKIPESRGCQVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DIFQVGECRRVQQLTLSPSAGLLVVLCGRGPSVRLFALAELENIEVAGAKIPESRGCQVL
1150 1160 1170 1180 1190 1200
1190 1200 1210 1220 1230 1240
pF1KE3 AAGSILQARTPVLCVAVKRQVLCYQLGPGPGPWQRRIRELQAPATVQSLGLLGDRLCVGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AAGSILQARTPVLCVAVKRQVLCYQLGPGPGPWQRRIRELQAPATVQSLGLLGDRLCVGA
1210 1220 1230 1240 1250 1260
1250 1260 1270 1280 1290 1300
pF1KE3 AGGFALYPLLNEAAPLALGAGLVPEELPPSRGGLGEALGAVELSLSEFLLLFTTAGIYVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AGGFALYPLLNEAAPLALGAGLVPEELPPSRGGLGEALGAVELSLSEFLLLFTTAGIYVD
1270 1280 1290 1300 1310 1320
1310 1320 1330 1340 1350 1360
pF1KE3 GAGRKSRGHELLWPAAPMGWGYAAPYLTVFSENSIDVFDVRRAEWVQTVPLKKVRPLNPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GAGRKSRGHELLWPAAPMGWGYAAPYLTVFSENSIDVFDVRRAEWVQTVPLKKVRPLNPE
1330 1340 1350 1360 1370 1380
1370 1380 1390 1400 1410 1420
pF1KE3 GSLFLYGTEKVRLTYLRNQLAEKDEFDIPDLTDNSRRQLFRTKSKRRFFFRVSEEQQKQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GSLFLYGTEKVRLTYLRNQLAEKDEFDIPDLTDNSRRQLFRTKSKRRFFFRVSEEQQKQQ
1390 1400 1410 1420 1430 1440
1430 1440 1450 1460 1470 1480
pF1KE3 RREMLKDPFVRSKLISPPTNFNHLVHVGPANGRPGARDKSPAPEEKGRVARGSGPQRPHS
:::::::::::::::::::::::::::::::::::::::::
XP_011 RREMLKDPFVRSKLISPPTNFNHLVHVGPANGRPGARDKSP
1450 1460 1470 1480
1490 1500 1510 1520 1530 1540
pF1KE3 FSEALRRPASMGSEGLGGDADPMKRKPWTSLSSESVSCPQGSLSPATSLMQVSERPRSLP
>>XP_011543460 (OMIM: 613991) PREDICTED: serine/threonin (1495 aa)
initn: 9145 init1: 5808 opt: 5808 Z-score: 2059.1 bits: 393.7 E(85289): 5.9e-108
Smith-Waterman score: 9011; 89.2% identity (91.1% similar) in 1569 aa overlap (1-1551:1-1495)
10 20 30 40 50 60
pF1KE3 MERRLRALEQLARGEAGGCPGLDGLLDLLLALHHELSSGPLRRERSVAQFLSWASPFVSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MERRLRALEQLARGEAGGCPGLDGLLDLLLALHHELSSGPLRRERSVAQFLSWASPFVSK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 VKELRLQRDDFEILKVIGRGAFGEVTVVRQRDTGQIFAMKMLHKWEMLKRAETACFREER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VKELRLQRDDFEILKVIGRGAFGEVTVVRQRDTGQIFAMKMLHKWEMLKRAETACFREER
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 DVLVKGDSRWVTTLHYAFQDEEYLYLVMDYYAGGDLLTLLSRFEDRLPPELAQFYLAEMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DVLVKGDSRWVTTLHYAFQDEEYLYLVMDYYAGGDLLTLLSRFEDRLPPELAQFYLAEMV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 LAIHSLHQLGYVHRDVKPDNVLLDVNGHIRLADFGSCLRLNTNGMVDSSVAVGTPDYISP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LAIHSLHQLGYVHRDVKPDNVLLDVNGHIRLADFGSCLRLNTNGMVDSSVAVGTPDYISP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 EILQAMEEGKGHYGPQCDWWSLGVCAYELLFGETPFYAESLVETYGKIMNHEDHLQFPPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EILQAMEEGKGHYGPQCDWWSLGVCAYELLFGETPFYAESLVETYGKIMNHEDHLQFPPD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 VPDVPASAQDLIRQLLCRQEERLGRGGLDDFRNHPFFEGVDWERLASSTAPYIPELRGPM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VPDVPASAQDLIRQLLCRQEERLGRGGLDDFRNHPFFEGVDWERLASSTAPYIPELRGPM
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 DTSNFDVDDDTLNHPGTLPPPSHGAFSGHHLPFVGFTYTSGSHSPESSSEAWAALERKLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DTSNFDVDDDTLNHPGTLPPPSHGAFSGHHLPFVGFTYTSGSHSPESSSEAWAALERKLQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 CLEQEKVELSRKHQEALHAPTDHRELEQLRKEVQTLRDRLPEMLRDKASLSQTDGPPAGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CLEQEKVELSRKHQEALHAPTDHRELEQLRKEVQTLRDRLPEMLRDKASLSQTDGPPAGS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 PGQDSDLRQELDRLHRELAEGRAGLQAQEQELCRAQGQQEELLQRLQEAQEREAATASQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PGQDSDLRQELDRLHRELAEGRAGLQAQEQELCRAQGQQEELLQRLQEAQEREAATASQT
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 RALSSQLEEARAAQRELEAQVSSLSRQVTQLQGQWEQRLEESSQAKTIHTASETNGMGPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RALSSQLEEARAAQRELEAQVSSLSRQVTQLQGQWEQRLEESSQAKTIHTASETNGMGPP
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 EGGPQEAQLRKEVAALREQLEQAHSHRPSGKEEALCQLQEENRRLSREQERLEAELAQEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EGGPQEAQLRKEVAALREQLEQAHSHRPSGKEEALCQLQEENRRLSREQERLEAELAQEQ
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 ESKQRLEGERRETESNWEAQLADILSWVNDEKVSRGYLQALATKMAEELESLRNVGTQTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ESKQRLEGERRETESNWEAQLADILSWVNDEKVSRGYLQALATKMAEELESLRNVGTQTL
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 PARPLDHQWKARRLQKMEASARLELQSALEAEIRAKQGLQERLTQVQEAQLQAERRLQEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PARPLDHQWKARRLQKMEASARLELQSALEAEIRAKQGLQERLTQVQEAQLQAERRLQEA
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE3 EKQSQALQQELAMLREELRARGPVDTKPSNSLIPFLSFRSSEKDSAKDPGISGEATRHGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKQSQALQQELAMLREELRARGPVDTKPSNSLIPFLSFRSSEKDSAKDPGISGEATRHGG
790 800 810 820 830 840
850 860 870 880
pF1KE3 EPDLRPEGRRSLRMGAVFPRAPTANTASTEGLPAK------------------PGSHTLR
::::::::::::::::::::::::::::::::::: :::::::
XP_011 EPDLRPEGRRSLRMGAVFPRAPTANTASTEGLPAKGWGMGPWEALGNGCPPPQPGSHTLR
850 860 870 880 890 900
890 900 910 920 930 940
pF1KE3 PRSFPSPTKCLRCTSLMLGLGRQGLGCDACGYFCHTTCAPQAPPCPVPPDLLRTALGVHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PRSFPSPTKCLRCTSLMLGLGRQGLGCDACGYFCHTTCAPQAPPCPVPPDLLRTALGVHP
910 920 930 940 950 960
950 960 970 980 990 1000
pF1KE3 ETGTGTAYEGFLSVPRPSGVRRGWQRVFAALSDSRLLLFDAPDLRLSPPSGALLQVLDLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ETGTGTAYEGFLSVPRPSGVRRGWQRVFAALSDSRLLLFDAPDLRLSPPSGALLQVLDLR
970 980 990 1000 1010 1020
1010 1020 1030 1040 1050 1060
pF1KE3 DPQFSATPVLASDVIHAQSRDLPRIFRVTTSQLAVPPTTCTVLLLAESEGERERWLQVLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DPQFSATPVLASDVIHAQSRDLPRIFRVTTSQLAVPPTTCTVLLLAESEGERERWLQVLG
1030 1040 1050 1060 1070 1080
1070 1080 1090 1100 1110 1120
pF1KE3 ELQRLLLDARPRPRPVYTLKEAYDNGLPLLPHTLCAAILDQDRLALGTEEGLFVIHLRSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELQRLLLDARPRPRPVYTLKEAYDNGLPLLPHTLCAAILDQDRLALGTEEGLFVIHLRSN
1090 1100 1110 1120 1130 1140
1130 1140 1150 1160 1170 1180
pF1KE3 DIFQVGECRRVQQLTLSPSAGLLVVLCGRGPSVRLFALAELENIEVAGAKIPESRGCQVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DIFQVGECRRVQQLTLSPSAGLLVVLCGRGPSVRLFALAELENIEVAGAKIPESRGCQVL
1150 1160 1170 1180 1190 1200
1190 1200 1210 1220 1230 1240
pF1KE3 AAGSILQARTPVLCVAVKRQVLCYQLGPGPGPWQRRIRELQAPATVQSLGLLGDRLCVGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AAGSILQARTPVLCVAVKRQVLCYQLGPGPGPWQRRIRELQAPATVQSLGLLGDRLCVGA
1210 1220 1230 1240 1250 1260
1250 1260 1270 1280 1290 1300
pF1KE3 AGGFALYPLLNEAAPLALGAGLVPEELPPSRGGLGEALGAVELSLSEFLLLFTTAGIYVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AGGFALYPLLNEAAPLALGAGLVPEELPPSRGGLGEALGAVELSLSEFLLLFTTAGIYVD
1270 1280 1290 1300 1310 1320
1310 1320 1330 1340 1350 1360
pF1KE3 GAGRKSRGHELLWPAAPMGWGYAAPYLTVFSENSIDVFDVRRAEWVQTVPLKKVRPLNPE
::::::::::::::::::::: ::: . .. : .:. : .: . : . :
XP_011 GAGRKSRGHELLWPAAPMGWG-AAP-----QSRGLPV-PLRHREGPPDLPQE---PAGRE
1330 1340 1350 1360 1370
1370 1380 1390 1400 1410 1420
pF1KE3 GSLFLYGTEKVRLTYLRNQLAEKDEFDIPDLTDNSRRQLFRTKSKRRFFFRVSEEQQKQQ
: . : . :.: : : . . . :. : ::. .
XP_011 GRVRHPGPH-------RQQPA-------PAVPHQEQAPLL--------FPRVGGAAEAAA
1380 1390 1400
1430 1440 1450 1460 1470 1480
pF1KE3 RREMLKDPFVRSKLISPPTNFNHLVHVGPANGRPGARDKSPAPEEKGRVARGSGPQRPHS
. . . :: . .:.. . .: : .: :
XP_011 QGDA-EGPFCALQ-----------AHLAAYQLQP--------PSTRGPCQR---------
1410 1420 1430
1490 1500 1510 1520 1530 1540
pF1KE3 FSEALRRPASMGSEGLGGDADPMKRKPWTSLSSESVSCPQGSLSPATSLMQVSERPRSLP
: :: ... :.:::::::::::::::::::::::::::::::::::::
XP_011 ---AARRQGQV----------PVKRKPWTSLSSESVSCPQGSLSPATSLMQVSERPRSLP
1440 1450 1460 1470 1480
1550
pF1KE3 LSPELESSP
:::::::::
XP_011 LSPELESSP
1490
>>XP_011543459 (OMIM: 613991) PREDICTED: serine/threonin (1530 aa)
initn: 8844 init1: 5808 opt: 5808 Z-score: 2059.0 bits: 393.7 E(85289): 6e-108
Smith-Waterman score: 8817; 98.6% identity (98.6% similar) in 1345 aa overlap (1-1327:1-1344)
10 20 30 40 50 60
pF1KE3 MERRLRALEQLARGEAGGCPGLDGLLDLLLALHHELSSGPLRRERSVAQFLSWASPFVSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MERRLRALEQLARGEAGGCPGLDGLLDLLLALHHELSSGPLRRERSVAQFLSWASPFVSK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 VKELRLQRDDFEILKVIGRGAFGEVTVVRQRDTGQIFAMKMLHKWEMLKRAETACFREER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VKELRLQRDDFEILKVIGRGAFGEVTVVRQRDTGQIFAMKMLHKWEMLKRAETACFREER
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 DVLVKGDSRWVTTLHYAFQDEEYLYLVMDYYAGGDLLTLLSRFEDRLPPELAQFYLAEMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DVLVKGDSRWVTTLHYAFQDEEYLYLVMDYYAGGDLLTLLSRFEDRLPPELAQFYLAEMV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 LAIHSLHQLGYVHRDVKPDNVLLDVNGHIRLADFGSCLRLNTNGMVDSSVAVGTPDYISP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LAIHSLHQLGYVHRDVKPDNVLLDVNGHIRLADFGSCLRLNTNGMVDSSVAVGTPDYISP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 EILQAMEEGKGHYGPQCDWWSLGVCAYELLFGETPFYAESLVETYGKIMNHEDHLQFPPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EILQAMEEGKGHYGPQCDWWSLGVCAYELLFGETPFYAESLVETYGKIMNHEDHLQFPPD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 VPDVPASAQDLIRQLLCRQEERLGRGGLDDFRNHPFFEGVDWERLASSTAPYIPELRGPM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VPDVPASAQDLIRQLLCRQEERLGRGGLDDFRNHPFFEGVDWERLASSTAPYIPELRGPM
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 DTSNFDVDDDTLNHPGTLPPPSHGAFSGHHLPFVGFTYTSGSHSPESSSEAWAALERKLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DTSNFDVDDDTLNHPGTLPPPSHGAFSGHHLPFVGFTYTSGSHSPESSSEAWAALERKLQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 CLEQEKVELSRKHQEALHAPTDHRELEQLRKEVQTLRDRLPEMLRDKASLSQTDGPPAGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CLEQEKVELSRKHQEALHAPTDHRELEQLRKEVQTLRDRLPEMLRDKASLSQTDGPPAGS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 PGQDSDLRQELDRLHRELAEGRAGLQAQEQELCRAQGQQEELLQRLQEAQEREAATASQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PGQDSDLRQELDRLHRELAEGRAGLQAQEQELCRAQGQQEELLQRLQEAQEREAATASQT
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 RALSSQLEEARAAQRELEAQVSSLSRQVTQLQGQWEQRLEESSQAKTIHTASETNGMGPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RALSSQLEEARAAQRELEAQVSSLSRQVTQLQGQWEQRLEESSQAKTIHTASETNGMGPP
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 EGGPQEAQLRKEVAALREQLEQAHSHRPSGKEEALCQLQEENRRLSREQERLEAELAQEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EGGPQEAQLRKEVAALREQLEQAHSHRPSGKEEALCQLQEENRRLSREQERLEAELAQEQ
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 ESKQRLEGERRETESNWEAQLADILSWVNDEKVSRGYLQALATKMAEELESLRNVGTQTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ESKQRLEGERRETESNWEAQLADILSWVNDEKVSRGYLQALATKMAEELESLRNVGTQTL
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 PARPLDHQWKARRLQKMEASARLELQSALEAEIRAKQGLQERLTQVQEAQLQAERRLQEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PARPLDHQWKARRLQKMEASARLELQSALEAEIRAKQGLQERLTQVQEAQLQAERRLQEA
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE3 EKQSQALQQELAMLREELRARGPVDTKPSNSLIPFLSFRSSEKDSAKDPGISGEATRHGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKQSQALQQELAMLREELRARGPVDTKPSNSLIPFLSFRSSEKDSAKDPGISGEATRHGG
790 800 810 820 830 840
850 860 870 880
pF1KE3 EPDLRPEGRRSLRMGAVFPRAPTANTASTEGLPAK------------------PGSHTLR
::::::::::::::::::::::::::::::::::: :::::::
XP_011 EPDLRPEGRRSLRMGAVFPRAPTANTASTEGLPAKGWGMGPWEALGNGCPPPQPGSHTLR
850 860 870 880 890 900
890 900 910 920 930 940
pF1KE3 PRSFPSPTKCLRCTSLMLGLGRQGLGCDACGYFCHTTCAPQAPPCPVPPDLLRTALGVHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PRSFPSPTKCLRCTSLMLGLGRQGLGCDACGYFCHTTCAPQAPPCPVPPDLLRTALGVHP
910 920 930 940 950 960
950 960 970 980 990 1000
pF1KE3 ETGTGTAYEGFLSVPRPSGVRRGWQRVFAALSDSRLLLFDAPDLRLSPPSGALLQVLDLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ETGTGTAYEGFLSVPRPSGVRRGWQRVFAALSDSRLLLFDAPDLRLSPPSGALLQVLDLR
970 980 990 1000 1010 1020
1010 1020 1030 1040 1050 1060
pF1KE3 DPQFSATPVLASDVIHAQSRDLPRIFRVTTSQLAVPPTTCTVLLLAESEGERERWLQVLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DPQFSATPVLASDVIHAQSRDLPRIFRVTTSQLAVPPTTCTVLLLAESEGERERWLQVLG
1030 1040 1050 1060 1070 1080
1070 1080 1090 1100 1110 1120
pF1KE3 ELQRLLLDARPRPRPVYTLKEAYDNGLPLLPHTLCAAILDQDRLALGTEEGLFVIHLRSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELQRLLLDARPRPRPVYTLKEAYDNGLPLLPHTLCAAILDQDRLALGTEEGLFVIHLRSN
1090 1100 1110 1120 1130 1140
1130 1140 1150 1160 1170 1180
pF1KE3 DIFQVGECRRVQQLTLSPSAGLLVVLCGRGPSVRLFALAELENIEVAGAKIPESRGCQVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DIFQVGECRRVQQLTLSPSAGLLVVLCGRGPSVRLFALAELENIEVAGAKIPESRGCQVL
1150 1160 1170 1180 1190 1200
1190 1200 1210 1220 1230 1240
pF1KE3 AAGSILQARTPVLCVAVKRQVLCYQLGPGPGPWQRRIRELQAPATVQSLGLLGDRLCVGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AAGSILQARTPVLCVAVKRQVLCYQLGPGPGPWQRRIRELQAPATVQSLGLLGDRLCVGA
1210 1220 1230 1240 1250 1260
1250 1260 1270 1280 1290 1300
pF1KE3 AGGFALYPLLNEAAPLALGAGLVPEELPPSRGGLGEALGAVELSLSEFLLLFTTAGIYVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AGGFALYPLLNEAAPLALGAGLVPEELPPSRGGLGEALGAVELSLSEFLLLFTTAGIYVD
1270 1280 1290 1300 1310 1320
1310 1320 1330 1340 1350 1360
pF1KE3 GAGRKSRGHELLWPAAPMGWGYAAPYLTVFSENSIDVFDVRRAEWVQTVPLKKVRPLNPE
::::::::::::::::::::: :::
XP_011 GAGRKSRGHELLWPAAPMGWG-AAPQSRGLPVPLRHREGPPDLPQEPAGREGRVRHPGPH
1330 1340 1350 1360 1370
>>XP_011543457 (OMIM: 613991) PREDICTED: serine/threonin (1569 aa)
initn: 5850 init1: 5808 opt: 5808 Z-score: 2058.9 bits: 393.8 E(85289): 6.1e-108
Smith-Waterman score: 10341; 98.9% identity (98.9% similar) in 1569 aa overlap (1-1551:1-1569)
10 20 30 40 50 60
pF1KE3 MERRLRALEQLARGEAGGCPGLDGLLDLLLALHHELSSGPLRRERSVAQFLSWASPFVSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MERRLRALEQLARGEAGGCPGLDGLLDLLLALHHELSSGPLRRERSVAQFLSWASPFVSK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 VKELRLQRDDFEILKVIGRGAFGEVTVVRQRDTGQIFAMKMLHKWEMLKRAETACFREER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VKELRLQRDDFEILKVIGRGAFGEVTVVRQRDTGQIFAMKMLHKWEMLKRAETACFREER
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 DVLVKGDSRWVTTLHYAFQDEEYLYLVMDYYAGGDLLTLLSRFEDRLPPELAQFYLAEMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DVLVKGDSRWVTTLHYAFQDEEYLYLVMDYYAGGDLLTLLSRFEDRLPPELAQFYLAEMV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 LAIHSLHQLGYVHRDVKPDNVLLDVNGHIRLADFGSCLRLNTNGMVDSSVAVGTPDYISP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LAIHSLHQLGYVHRDVKPDNVLLDVNGHIRLADFGSCLRLNTNGMVDSSVAVGTPDYISP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 EILQAMEEGKGHYGPQCDWWSLGVCAYELLFGETPFYAESLVETYGKIMNHEDHLQFPPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EILQAMEEGKGHYGPQCDWWSLGVCAYELLFGETPFYAESLVETYGKIMNHEDHLQFPPD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 VPDVPASAQDLIRQLLCRQEERLGRGGLDDFRNHPFFEGVDWERLASSTAPYIPELRGPM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VPDVPASAQDLIRQLLCRQEERLGRGGLDDFRNHPFFEGVDWERLASSTAPYIPELRGPM
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 DTSNFDVDDDTLNHPGTLPPPSHGAFSGHHLPFVGFTYTSGSHSPESSSEAWAALERKLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DTSNFDVDDDTLNHPGTLPPPSHGAFSGHHLPFVGFTYTSGSHSPESSSEAWAALERKLQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 CLEQEKVELSRKHQEALHAPTDHRELEQLRKEVQTLRDRLPEMLRDKASLSQTDGPPAGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CLEQEKVELSRKHQEALHAPTDHRELEQLRKEVQTLRDRLPEMLRDKASLSQTDGPPAGS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 PGQDSDLRQELDRLHRELAEGRAGLQAQEQELCRAQGQQEELLQRLQEAQEREAATASQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PGQDSDLRQELDRLHRELAEGRAGLQAQEQELCRAQGQQEELLQRLQEAQEREAATASQT
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 RALSSQLEEARAAQRELEAQVSSLSRQVTQLQGQWEQRLEESSQAKTIHTASETNGMGPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RALSSQLEEARAAQRELEAQVSSLSRQVTQLQGQWEQRLEESSQAKTIHTASETNGMGPP
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 EGGPQEAQLRKEVAALREQLEQAHSHRPSGKEEALCQLQEENRRLSREQERLEAELAQEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EGGPQEAQLRKEVAALREQLEQAHSHRPSGKEEALCQLQEENRRLSREQERLEAELAQEQ
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 ESKQRLEGERRETESNWEAQLADILSWVNDEKVSRGYLQALATKMAEELESLRNVGTQTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ESKQRLEGERRETESNWEAQLADILSWVNDEKVSRGYLQALATKMAEELESLRNVGTQTL
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 PARPLDHQWKARRLQKMEASARLELQSALEAEIRAKQGLQERLTQVQEAQLQAERRLQEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PARPLDHQWKARRLQKMEASARLELQSALEAEIRAKQGLQERLTQVQEAQLQAERRLQEA
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE3 EKQSQALQQELAMLREELRARGPVDTKPSNSLIPFLSFRSSEKDSAKDPGISGEATRHGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKQSQALQQELAMLREELRARGPVDTKPSNSLIPFLSFRSSEKDSAKDPGISGEATRHGG
790 800 810 820 830 840
850 860 870 880
pF1KE3 EPDLRPEGRRSLRMGAVFPRAPTANTASTEGLPAK------------------PGSHTLR
::::::::::::::::::::::::::::::::::: :::::::
XP_011 EPDLRPEGRRSLRMGAVFPRAPTANTASTEGLPAKGWGMGPWEALGNGCPPPQPGSHTLR
850 860 870 880 890 900
890 900 910 920 930 940
pF1KE3 PRSFPSPTKCLRCTSLMLGLGRQGLGCDACGYFCHTTCAPQAPPCPVPPDLLRTALGVHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PRSFPSPTKCLRCTSLMLGLGRQGLGCDACGYFCHTTCAPQAPPCPVPPDLLRTALGVHP
910 920 930 940 950 960
950 960 970 980 990 1000
pF1KE3 ETGTGTAYEGFLSVPRPSGVRRGWQRVFAALSDSRLLLFDAPDLRLSPPSGALLQVLDLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ETGTGTAYEGFLSVPRPSGVRRGWQRVFAALSDSRLLLFDAPDLRLSPPSGALLQVLDLR
970 980 990 1000 1010 1020
1010 1020 1030 1040 1050 1060
pF1KE3 DPQFSATPVLASDVIHAQSRDLPRIFRVTTSQLAVPPTTCTVLLLAESEGERERWLQVLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DPQFSATPVLASDVIHAQSRDLPRIFRVTTSQLAVPPTTCTVLLLAESEGERERWLQVLG
1030 1040 1050 1060 1070 1080
1070 1080 1090 1100 1110 1120
pF1KE3 ELQRLLLDARPRPRPVYTLKEAYDNGLPLLPHTLCAAILDQDRLALGTEEGLFVIHLRSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELQRLLLDARPRPRPVYTLKEAYDNGLPLLPHTLCAAILDQDRLALGTEEGLFVIHLRSN
1090 1100 1110 1120 1130 1140
1130 1140 1150 1160 1170 1180
pF1KE3 DIFQVGECRRVQQLTLSPSAGLLVVLCGRGPSVRLFALAELENIEVAGAKIPESRGCQVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DIFQVGECRRVQQLTLSPSAGLLVVLCGRGPSVRLFALAELENIEVAGAKIPESRGCQVL
1150 1160 1170 1180 1190 1200
1190 1200 1210 1220 1230 1240
pF1KE3 AAGSILQARTPVLCVAVKRQVLCYQLGPGPGPWQRRIRELQAPATVQSLGLLGDRLCVGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AAGSILQARTPVLCVAVKRQVLCYQLGPGPGPWQRRIRELQAPATVQSLGLLGDRLCVGA
1210 1220 1230 1240 1250 1260
1250 1260 1270 1280 1290 1300
pF1KE3 AGGFALYPLLNEAAPLALGAGLVPEELPPSRGGLGEALGAVELSLSEFLLLFTTAGIYVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AGGFALYPLLNEAAPLALGAGLVPEELPPSRGGLGEALGAVELSLSEFLLLFTTAGIYVD
1270 1280 1290 1300 1310 1320
1310 1320 1330 1340 1350 1360
pF1KE3 GAGRKSRGHELLWPAAPMGWGYAAPYLTVFSENSIDVFDVRRAEWVQTVPLKKVRPLNPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GAGRKSRGHELLWPAAPMGWGYAAPYLTVFSENSIDVFDVRRAEWVQTVPLKKVRPLNPE
1330 1340 1350 1360 1370 1380
1370 1380 1390 1400 1410 1420
pF1KE3 GSLFLYGTEKVRLTYLRNQLAEKDEFDIPDLTDNSRRQLFRTKSKRRFFFRVSEEQQKQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GSLFLYGTEKVRLTYLRNQLAEKDEFDIPDLTDNSRRQLFRTKSKRRFFFRVSEEQQKQQ
1390 1400 1410 1420 1430 1440
1430 1440 1450 1460 1470 1480
pF1KE3 RREMLKDPFVRSKLISPPTNFNHLVHVGPANGRPGARDKSPAPEEKGRVARGSGPQRPHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RREMLKDPFVRSKLISPPTNFNHLVHVGPANGRPGARDKSPAPEEKGRVARGSGPQRPHS
1450 1460 1470 1480 1490 1500
1490 1500 1510 1520 1530 1540
pF1KE3 FSEALRRPASMGSEGLGGDADPMKRKPWTSLSSESVSCPQGSLSPATSLMQVSERPRSLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FSEALRRPASMGSEGLGGDADPMKRKPWTSLSSESVSCPQGSLSPATSLMQVSERPRSLP
1510 1520 1530 1540 1550 1560
1550
pF1KE3 LSPELESSP
:::::::::
XP_011 LSPELESSP
>>XP_016873485 (OMIM: 613991) PREDICTED: serine/threonin (1568 aa)
initn: 10028 init1: 5452 opt: 5790 Z-score: 2052.6 bits: 392.6 E(85289): 1.4e-107
Smith-Waterman score: 10323; 98.8% identity (98.8% similar) in 1569 aa overlap (1-1551:1-1568)
10 20 30 40 50 60
pF1KE3 MERRLRALEQLARGEAGGCPGLDGLLDLLLALHHELSSGPLRRERSVAQFLSWASPFVSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MERRLRALEQLARGEAGGCPGLDGLLDLLLALHHELSSGPLRRERSVAQFLSWASPFVSK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 VKELRLQRDDFEILKVIGRGAFGEVTVVRQRDTGQIFAMKMLHKWEMLKRAETACFREER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VKELRLQRDDFEILKVIGRGAFGEVTVVRQRDTGQIFAMKMLHKWEMLKRAETACFREER
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 DVLVKGDSRWVTTLHYAFQDEEYLYLVMDYYAGGDLLTLLSRFEDRLPPELAQFYLAEMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DVLVKGDSRWVTTLHYAFQDEEYLYLVMDYYAGGDLLTLLSRFEDRLPPELAQFYLAEMV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 LAIHSLHQLGYVHRDVKPDNVLLDVNGHIRLADFGSCLRLNTNGMVDSSVAVGTPDYISP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAIHSLHQLGYVHRDVKPDNVLLDVNGHIRLADFGSCLRLNTNGMVDSSVAVGTPDYISP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 EILQAMEEGKGHYGPQCDWWSLGVCAYELLFGETPFYAESLVETYGKIMNHEDHLQFPPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EILQAMEEGKGHYGPQCDWWSLGVCAYELLFGETPFYAESLVETYGKIMNHEDHLQFPPD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 VPDVPASAQDLIRQLLCRQEERLGRGGLDDFRNHPFFEGVDWERLASSTAPYIPELRGPM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VPDVPASAQDLIRQLLCRQEERLGRGGLDDFRNHPFFEGVDWERLASSTAPYIPELRGPM
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 DTSNFDVDDDTLNHPGTLPPPSHGAFSGHHLPFVGFTYTSGSHSPESSSEAWAALERKLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DTSNFDVDDDTLNHPGTLPPPSHGAFSGHHLPFVGFTYTSGSHSPESSSEAWAALERKLQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 CLEQEKVELSRKHQEALHAPTDHRELEQLRKEVQTLRDRLPEMLRDKASLSQTDGPPAGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CLEQEKVELSRKHQEALHAPTDHRELEQLRKEVQTLRDRLPEMLRDKASLSQTDGPPAGS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 PGQDSDLRQELDRLHRELAEGRAGLQAQEQELCRAQGQQEELLQRLQEAQEREAATASQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGQDSDLRQELDRLHRELAEGRAGLQAQEQELCRAQGQQEELLQRLQEAQEREAATASQT
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 RALSSQLEEARAAQRELEAQVSSLSRQVTQLQGQWEQRLEESSQAKTIHTASETNGMGPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RALSSQLEEARAAQRELEAQVSSLSRQVTQLQGQWEQRLEESSQAKTIHTASETNGMGPP
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 EGGPQEAQLRKEVAALREQLEQAHSHRPSGKEEALCQLQEENRRLSREQERLEAELAQEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EGGPQEAQLRKEVAALREQLEQAHSHRPSGKEEALCQLQEENRRLSREQERLEAELAQEQ
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 ESKQRLEGERRETESNWEAQLADILSWVNDEKVSRGYLQALATKMAEELESLRNVGTQTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESKQRLEGERRETESNWEAQLADILSWVNDEKVSRGYLQALATKMAEELESLRNVGTQTL
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 PARPLDHQWKARRLQKMEASARLELQSALEAEIRAKQGLQERLTQVQEAQLQAERRLQEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PARPLDHQWKARRLQKMEASARLELQSALEAEIRAKQGLQERLTQVQEAQLQAERRLQEA
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE3 EKQSQALQQELAMLREELRARGPVDTKPSNSLIPFLSFRSSEKDSAKDPGISGEATRHGG
:::::::::::::::::::::::::::::::::::::::::: :::::::::::::::::
XP_016 EKQSQALQQELAMLREELRARGPVDTKPSNSLIPFLSFRSSE-DSAKDPGISGEATRHGG
790 800 810 820 830
850 860 870 880
pF1KE3 EPDLRPEGRRSLRMGAVFPRAPTANTASTEGLPAK------------------PGSHTLR
::::::::::::::::::::::::::::::::::: :::::::
XP_016 EPDLRPEGRRSLRMGAVFPRAPTANTASTEGLPAKGWGMGPWEALGNGCPPPQPGSHTLR
840 850 860 870 880 890
890 900 910 920 930 940
pF1KE3 PRSFPSPTKCLRCTSLMLGLGRQGLGCDACGYFCHTTCAPQAPPCPVPPDLLRTALGVHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PRSFPSPTKCLRCTSLMLGLGRQGLGCDACGYFCHTTCAPQAPPCPVPPDLLRTALGVHP
900 910 920 930 940 950
950 960 970 980 990 1000
pF1KE3 ETGTGTAYEGFLSVPRPSGVRRGWQRVFAALSDSRLLLFDAPDLRLSPPSGALLQVLDLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ETGTGTAYEGFLSVPRPSGVRRGWQRVFAALSDSRLLLFDAPDLRLSPPSGALLQVLDLR
960 970 980 990 1000 1010
1010 1020 1030 1040 1050 1060
pF1KE3 DPQFSATPVLASDVIHAQSRDLPRIFRVTTSQLAVPPTTCTVLLLAESEGERERWLQVLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DPQFSATPVLASDVIHAQSRDLPRIFRVTTSQLAVPPTTCTVLLLAESEGERERWLQVLG
1020 1030 1040 1050 1060 1070
1070 1080 1090 1100 1110 1120
pF1KE3 ELQRLLLDARPRPRPVYTLKEAYDNGLPLLPHTLCAAILDQDRLALGTEEGLFVIHLRSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELQRLLLDARPRPRPVYTLKEAYDNGLPLLPHTLCAAILDQDRLALGTEEGLFVIHLRSN
1080 1090 1100 1110 1120 1130
1130 1140 1150 1160 1170 1180
pF1KE3 DIFQVGECRRVQQLTLSPSAGLLVVLCGRGPSVRLFALAELENIEVAGAKIPESRGCQVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DIFQVGECRRVQQLTLSPSAGLLVVLCGRGPSVRLFALAELENIEVAGAKIPESRGCQVL
1140 1150 1160 1170 1180 1190
1190 1200 1210 1220 1230 1240
pF1KE3 AAGSILQARTPVLCVAVKRQVLCYQLGPGPGPWQRRIRELQAPATVQSLGLLGDRLCVGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AAGSILQARTPVLCVAVKRQVLCYQLGPGPGPWQRRIRELQAPATVQSLGLLGDRLCVGA
1200 1210 1220 1230 1240 1250
1250 1260 1270 1280 1290 1300
pF1KE3 AGGFALYPLLNEAAPLALGAGLVPEELPPSRGGLGEALGAVELSLSEFLLLFTTAGIYVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AGGFALYPLLNEAAPLALGAGLVPEELPPSRGGLGEALGAVELSLSEFLLLFTTAGIYVD
1260 1270 1280 1290 1300 1310
1310 1320 1330 1340 1350 1360
pF1KE3 GAGRKSRGHELLWPAAPMGWGYAAPYLTVFSENSIDVFDVRRAEWVQTVPLKKVRPLNPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GAGRKSRGHELLWPAAPMGWGYAAPYLTVFSENSIDVFDVRRAEWVQTVPLKKVRPLNPE
1320 1330 1340 1350 1360 1370
1370 1380 1390 1400 1410 1420
pF1KE3 GSLFLYGTEKVRLTYLRNQLAEKDEFDIPDLTDNSRRQLFRTKSKRRFFFRVSEEQQKQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSLFLYGTEKVRLTYLRNQLAEKDEFDIPDLTDNSRRQLFRTKSKRRFFFRVSEEQQKQQ
1380 1390 1400 1410 1420 1430
1430 1440 1450 1460 1470 1480
pF1KE3 RREMLKDPFVRSKLISPPTNFNHLVHVGPANGRPGARDKSPAPEEKGRVARGSGPQRPHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RREMLKDPFVRSKLISPPTNFNHLVHVGPANGRPGARDKSPAPEEKGRVARGSGPQRPHS
1440 1450 1460 1470 1480 1490
1490 1500 1510 1520 1530 1540
pF1KE3 FSEALRRPASMGSEGLGGDADPMKRKPWTSLSSESVSCPQGSLSPATSLMQVSERPRSLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FSEALRRPASMGSEGLGGDADPMKRKPWTSLSSESVSCPQGSLSPATSLMQVSERPRSLP
1500 1510 1520 1530 1540 1550
1550
pF1KE3 LSPELESSP
:::::::::
XP_016 LSPELESSP
1560
>>XP_011543462 (OMIM: 613991) PREDICTED: serine/threonin (1471 aa)
initn: 5210 init1: 5168 opt: 5168 Z-score: 1835.2 bits: 352.3 E(85289): 1.7e-95
Smith-Waterman score: 9701; 98.8% identity (98.8% similar) in 1471 aa overlap (99-1551:1-1471)
70 80 90 100 110 120
pF1KE3 DDFEILKVIGRGAFGEVTVVRQRDTGQIFAMKMLHKWEMLKRAETACFREERDVLVKGDS
::::::::::::::::::::::::::::::
XP_011 MKMLHKWEMLKRAETACFREERDVLVKGDS
10 20 30
130 140 150 160 170 180
pF1KE3 RWVTTLHYAFQDEEYLYLVMDYYAGGDLLTLLSRFEDRLPPELAQFYLAEMVLAIHSLHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RWVTTLHYAFQDEEYLYLVMDYYAGGDLLTLLSRFEDRLPPELAQFYLAEMVLAIHSLHQ
40 50 60 70 80 90
190 200 210 220 230 240
pF1KE3 LGYVHRDVKPDNVLLDVNGHIRLADFGSCLRLNTNGMVDSSVAVGTPDYISPEILQAMEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LGYVHRDVKPDNVLLDVNGHIRLADFGSCLRLNTNGMVDSSVAVGTPDYISPEILQAMEE
100 110 120 130 140 150
250 260 270 280 290 300
pF1KE3 GKGHYGPQCDWWSLGVCAYELLFGETPFYAESLVETYGKIMNHEDHLQFPPDVPDVPASA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GKGHYGPQCDWWSLGVCAYELLFGETPFYAESLVETYGKIMNHEDHLQFPPDVPDVPASA
160 170 180 190 200 210
310 320 330 340 350 360
pF1KE3 QDLIRQLLCRQEERLGRGGLDDFRNHPFFEGVDWERLASSTAPYIPELRGPMDTSNFDVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QDLIRQLLCRQEERLGRGGLDDFRNHPFFEGVDWERLASSTAPYIPELRGPMDTSNFDVD
220 230 240 250 260 270
370 380 390 400 410 420
pF1KE3 DDTLNHPGTLPPPSHGAFSGHHLPFVGFTYTSGSHSPESSSEAWAALERKLQCLEQEKVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DDTLNHPGTLPPPSHGAFSGHHLPFVGFTYTSGSHSPESSSEAWAALERKLQCLEQEKVE
280 290 300 310 320 330
430 440 450 460 470 480
pF1KE3 LSRKHQEALHAPTDHRELEQLRKEVQTLRDRLPEMLRDKASLSQTDGPPAGSPGQDSDLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSRKHQEALHAPTDHRELEQLRKEVQTLRDRLPEMLRDKASLSQTDGPPAGSPGQDSDLR
340 350 360 370 380 390
490 500 510 520 530 540
pF1KE3 QELDRLHRELAEGRAGLQAQEQELCRAQGQQEELLQRLQEAQEREAATASQTRALSSQLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QELDRLHRELAEGRAGLQAQEQELCRAQGQQEELLQRLQEAQEREAATASQTRALSSQLE
400 410 420 430 440 450
550 560 570 580 590 600
pF1KE3 EARAAQRELEAQVSSLSRQVTQLQGQWEQRLEESSQAKTIHTASETNGMGPPEGGPQEAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EARAAQRELEAQVSSLSRQVTQLQGQWEQRLEESSQAKTIHTASETNGMGPPEGGPQEAQ
460 470 480 490 500 510
610 620 630 640 650 660
pF1KE3 LRKEVAALREQLEQAHSHRPSGKEEALCQLQEENRRLSREQERLEAELAQEQESKQRLEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRKEVAALREQLEQAHSHRPSGKEEALCQLQEENRRLSREQERLEAELAQEQESKQRLEG
520 530 540 550 560 570
670 680 690 700 710 720
pF1KE3 ERRETESNWEAQLADILSWVNDEKVSRGYLQALATKMAEELESLRNVGTQTLPARPLDHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ERRETESNWEAQLADILSWVNDEKVSRGYLQALATKMAEELESLRNVGTQTLPARPLDHQ
580 590 600 610 620 630
730 740 750 760 770 780
pF1KE3 WKARRLQKMEASARLELQSALEAEIRAKQGLQERLTQVQEAQLQAERRLQEAEKQSQALQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WKARRLQKMEASARLELQSALEAEIRAKQGLQERLTQVQEAQLQAERRLQEAEKQSQALQ
640 650 660 670 680 690
790 800 810 820 830 840
pF1KE3 QELAMLREELRARGPVDTKPSNSLIPFLSFRSSEKDSAKDPGISGEATRHGGEPDLRPEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QELAMLREELRARGPVDTKPSNSLIPFLSFRSSEKDSAKDPGISGEATRHGGEPDLRPEG
700 710 720 730 740 750
850 860 870 880 890
pF1KE3 RRSLRMGAVFPRAPTANTASTEGLPAK------------------PGSHTLRPRSFPSPT
::::::::::::::::::::::::::: :::::::::::::::
XP_011 RRSLRMGAVFPRAPTANTASTEGLPAKGWGMGPWEALGNGCPPPQPGSHTLRPRSFPSPT
760 770 780 790 800 810
900 910 920 930 940 950
pF1KE3 KCLRCTSLMLGLGRQGLGCDACGYFCHTTCAPQAPPCPVPPDLLRTALGVHPETGTGTAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KCLRCTSLMLGLGRQGLGCDACGYFCHTTCAPQAPPCPVPPDLLRTALGVHPETGTGTAY
820 830 840 850 860 870
960 970 980 990 1000 1010
pF1KE3 EGFLSVPRPSGVRRGWQRVFAALSDSRLLLFDAPDLRLSPPSGALLQVLDLRDPQFSATP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EGFLSVPRPSGVRRGWQRVFAALSDSRLLLFDAPDLRLSPPSGALLQVLDLRDPQFSATP
880 890 900 910 920 930
1020 1030 1040 1050 1060 1070
pF1KE3 VLASDVIHAQSRDLPRIFRVTTSQLAVPPTTCTVLLLAESEGERERWLQVLGELQRLLLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLASDVIHAQSRDLPRIFRVTTSQLAVPPTTCTVLLLAESEGERERWLQVLGELQRLLLD
940 950 960 970 980 990
1080 1090 1100 1110 1120 1130
pF1KE3 ARPRPRPVYTLKEAYDNGLPLLPHTLCAAILDQDRLALGTEEGLFVIHLRSNDIFQVGEC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ARPRPRPVYTLKEAYDNGLPLLPHTLCAAILDQDRLALGTEEGLFVIHLRSNDIFQVGEC
1000 1010 1020 1030 1040 1050
1140 1150 1160 1170 1180 1190
pF1KE3 RRVQQLTLSPSAGLLVVLCGRGPSVRLFALAELENIEVAGAKIPESRGCQVLAAGSILQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RRVQQLTLSPSAGLLVVLCGRGPSVRLFALAELENIEVAGAKIPESRGCQVLAAGSILQA
1060 1070 1080 1090 1100 1110
1200 1210 1220 1230 1240 1250
pF1KE3 RTPVLCVAVKRQVLCYQLGPGPGPWQRRIRELQAPATVQSLGLLGDRLCVGAAGGFALYP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RTPVLCVAVKRQVLCYQLGPGPGPWQRRIRELQAPATVQSLGLLGDRLCVGAAGGFALYP
1120 1130 1140 1150 1160 1170
1260 1270 1280 1290 1300 1310
pF1KE3 LLNEAAPLALGAGLVPEELPPSRGGLGEALGAVELSLSEFLLLFTTAGIYVDGAGRKSRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLNEAAPLALGAGLVPEELPPSRGGLGEALGAVELSLSEFLLLFTTAGIYVDGAGRKSRG
1180 1190 1200 1210 1220 1230
1320 1330 1340 1350 1360 1370
pF1KE3 HELLWPAAPMGWGYAAPYLTVFSENSIDVFDVRRAEWVQTVPLKKVRPLNPEGSLFLYGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HELLWPAAPMGWGYAAPYLTVFSENSIDVFDVRRAEWVQTVPLKKVRPLNPEGSLFLYGT
1240 1250 1260 1270 1280 1290
1380 1390 1400 1410 1420 1430
pF1KE3 EKVRLTYLRNQLAEKDEFDIPDLTDNSRRQLFRTKSKRRFFFRVSEEQQKQQRREMLKDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKVRLTYLRNQLAEKDEFDIPDLTDNSRRQLFRTKSKRRFFFRVSEEQQKQQRREMLKDP
1300 1310 1320 1330 1340 1350
1440 1450 1460 1470 1480 1490
pF1KE3 FVRSKLISPPTNFNHLVHVGPANGRPGARDKSPAPEEKGRVARGSGPQRPHSFSEALRRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FVRSKLISPPTNFNHLVHVGPANGRPGARDKSPAPEEKGRVARGSGPQRPHSFSEALRRP
1360 1370 1380 1390 1400 1410
1500 1510 1520 1530 1540 1550
pF1KE3 ASMGSEGLGGDADPMKRKPWTSLSSESVSCPQGSLSPATSLMQVSERPRSLPLSPELESS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASMGSEGLGGDADPMKRKPWTSLSSESVSCPQGSLSPATSLMQVSERPRSLPLSPELESS
1420 1430 1440 1450 1460 1470
pF1KE3 P
:
XP_011 P
1551 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 17:26:07 2016 done: Mon Nov 7 17:26:11 2016
Total Scan time: 22.450 Total Display time: 0.540
Function used was FASTA [36.3.4 Apr, 2011]