Result of FASTA (ccds) for
pFN21AE3454
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3454, 1328 aa
1>>>pF1KE3454 1328 - 1328 aa - 1328 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.7821+/-0.0015; mu= 5.6485+/- 0.087
mean_var=239.8199+/-54.361, 0's: 0 Z-trim(105.3): 725 B-trim: 467 in 1/48
Lambda= 0.082819
statistics sampled from 7526 (8344) to 7526 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.601), E-opt: 0.2 (0.256), width: 16
Scan time: 5.520
The best scores are: opt bits E(32554)
CCDS2176.2 MAP3K19 gene_id:80122|Hs108|chr2 (1328) 8850 1072.8 0
CCDS63020.1 MAP3K19 gene_id:80122|Hs108|chr2 (1215) 7604 923.8 0
CCDS33293.1 MAP3K19 gene_id:80122|Hs108|chr2 ( 510) 2055 260.5 8.5e-69
CCDS63021.1 MAP3K19 gene_id:80122|Hs108|chr2 ( 460) 1731 221.7 3.5e-57
CCDS63022.1 MAP3K19 gene_id:80122|Hs108|chr2 ( 462) 1503 194.5 5.7e-49
CCDS82186.1 MAP3K3 gene_id:4215|Hs108|chr17 ( 622) 807 111.5 7.6e-24
CCDS32702.1 MAP3K3 gene_id:4215|Hs108|chr17 ( 626) 807 111.5 7.6e-24
CCDS32701.1 MAP3K3 gene_id:4215|Hs108|chr17 ( 657) 807 111.5 7.9e-24
CCDS46404.1 MAP3K2 gene_id:10746|Hs108|chr2 ( 619) 797 110.3 1.7e-23
CCDS35212.2 MAP3K15 gene_id:389840|Hs108|chrX (1313) 684 97.0 3.5e-19
CCDS5179.1 MAP3K5 gene_id:4217|Hs108|chr6 (1374) 663 94.6 2e-18
CCDS72738.1 MAP3K6 gene_id:9064|Hs108|chr1 (1280) 646 92.5 7.9e-18
CCDS299.1 MAP3K6 gene_id:9064|Hs108|chr1 (1288) 646 92.5 8e-18
CCDS43318.1 MAP3K1 gene_id:4214|Hs108|chr5 (1512) 622 89.7 6.5e-17
CCDS34566.1 MAP3K4 gene_id:4216|Hs108|chr6 (1558) 613 88.6 1.4e-16
CCDS75544.1 MAP3K4 gene_id:4216|Hs108|chr6 (1604) 613 88.6 1.4e-16
CCDS34565.1 MAP3K4 gene_id:4216|Hs108|chr6 (1608) 613 88.6 1.4e-16
CCDS58707.1 MAP4K3 gene_id:8491|Hs108|chr2 ( 873) 569 83.1 3.5e-15
CCDS1803.1 MAP4K3 gene_id:8491|Hs108|chr2 ( 894) 569 83.2 3.6e-15
CCDS42564.1 MAP4K1 gene_id:11184|Hs108|chr19 ( 821) 530 78.5 8.5e-14
CCDS59385.1 MAP4K1 gene_id:11184|Hs108|chr19 ( 833) 530 78.5 8.6e-14
CCDS81582.1 MAP4K2 gene_id:5871|Hs108|chr11 ( 812) 528 78.2 1e-13
CCDS8082.1 MAP4K2 gene_id:5871|Hs108|chr11 ( 820) 528 78.2 1e-13
CCDS14631.1 STK26 gene_id:51765|Hs108|chrX ( 416) 522 77.2 1e-13
CCDS32001.1 STK24 gene_id:8428|Hs108|chr13 ( 431) 518 76.8 1.4e-13
CCDS9488.1 STK24 gene_id:8428|Hs108|chr13 ( 443) 518 76.8 1.5e-13
CCDS2549.1 STK25 gene_id:10494|Hs108|chr2 ( 426) 517 76.7 1.6e-13
CCDS6854.1 NEK6 gene_id:10783|Hs108|chr9 ( 313) 505 75.1 3.4e-13
CCDS55338.1 NEK6 gene_id:10783|Hs108|chr9 ( 331) 505 75.1 3.5e-13
CCDS55339.1 NEK6 gene_id:10783|Hs108|chr9 ( 338) 505 75.1 3.5e-13
CCDS48015.1 NEK6 gene_id:10783|Hs108|chr9 ( 347) 505 75.1 3.6e-13
CCDS54673.1 TNIK gene_id:23043|Hs108|chr3 (1268) 515 76.8 4e-13
CCDS54674.1 TNIK gene_id:23043|Hs108|chr3 (1276) 515 76.8 4.1e-13
CCDS54677.1 TNIK gene_id:23043|Hs108|chr3 (1297) 515 76.9 4.1e-13
CCDS54678.1 TNIK gene_id:23043|Hs108|chr3 (1305) 515 76.9 4.1e-13
CCDS54675.1 TNIK gene_id:23043|Hs108|chr3 (1323) 515 76.9 4.2e-13
CCDS54676.1 TNIK gene_id:23043|Hs108|chr3 (1331) 515 76.9 4.2e-13
CCDS54679.1 TNIK gene_id:23043|Hs108|chr3 (1352) 515 76.9 4.2e-13
CCDS46956.1 TNIK gene_id:23043|Hs108|chr3 (1360) 515 76.9 4.3e-13
CCDS2863.1 NEK4 gene_id:6787|Hs108|chr3 ( 841) 505 75.5 6.9e-13
CCDS82487.1 MAP4K4 gene_id:9448|Hs108|chr2 (1165) 507 75.9 7.4e-13
CCDS56130.1 MAP4K4 gene_id:9448|Hs108|chr2 (1239) 507 75.9 7.7e-13
CCDS74546.1 MAP4K4 gene_id:9448|Hs108|chr2 (1273) 507 75.9 7.9e-13
CCDS1394.1 NEK7 gene_id:140609|Hs108|chr1 ( 302) 493 73.6 8.8e-13
CCDS76334.1 SLK gene_id:9748|Hs108|chr10 (1204) 505 75.6 8.9e-13
CCDS7553.1 SLK gene_id:9748|Hs108|chr10 (1235) 505 75.6 9.1e-13
CCDS7148.1 MYO3A gene_id:53904|Hs108|chr10 (1616) 505 75.7 1.1e-12
CCDS45589.1 MINK1 gene_id:50488|Hs108|chr17 (1303) 498 74.8 1.7e-12
CCDS45590.1 MINK1 gene_id:50488|Hs108|chr17 (1312) 498 74.8 1.7e-12
CCDS45588.1 MINK1 gene_id:50488|Hs108|chr17 (1332) 498 74.8 1.7e-12
>>CCDS2176.2 MAP3K19 gene_id:80122|Hs108|chr2 (1328 aa)
initn: 8850 init1: 8850 opt: 8850 Z-score: 5731.0 bits: 1072.8 E(32554): 0
Smith-Waterman score: 8850; 100.0% identity (100.0% similar) in 1328 aa overlap (1-1328:1-1328)
10 20 30 40 50 60
pF1KE3 MSSMPKPERHAESLLDICHDTNSSPTDLMTVTKNQNIILQSISRSEEFDQDGDCSHSTLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS21 MSSMPKPERHAESLLDICHDTNSSPTDLMTVTKNQNIILQSISRSEEFDQDGDCSHSTLV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 NEEEDPSGGRQDWQPRTEGVEITVTFPRDVSPPQEMSQEDLKEKNLINSSLQEWAQAHAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS21 NEEEDPSGGRQDWQPRTEGVEITVTFPRDVSPPQEMSQEDLKEKNLINSSLQEWAQAHAV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 SHPNEIETVELRKKKLTMRPLVLQKEESSRELCNVNLGFLLPRSCLELNISKSVTREDAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS21 SHPNEIETVELRKKKLTMRPLVLQKEESSRELCNVNLGFLLPRSCLELNISKSVTREDAP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 HFLKEQQRKSEEFSTSHMKYSGRSIKFLLPPLSLLPTRSGVLTIPQNHKFPKEKERNIPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS21 HFLKEQQRKSEEFSTSHMKYSGRSIKFLLPPLSLLPTRSGVLTIPQNHKFPKEKERNIPS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 LTSFVPKLSVSVRQSDELSPSNEPPGALVKSLMDPTLRSSDGFIWSRNMCSFPKTNHHRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS21 LTSFVPKLSVSVRQSDELSPSNEPPGALVKSLMDPTLRSSDGFIWSRNMCSFPKTNHHRQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 CLEKEENWKSKEIEECNKIEITHFEKGQSLVSFENLKEGNIPAVREEDIDCHGSKTRKPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS21 CLEKEENWKSKEIEECNKIEITHFEKGQSLVSFENLKEGNIPAVREEDIDCHGSKTRKPE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 EENSQYLSSRKNESSVAKNYEQDPEIVCTIPSKFQETQHSEITPSQDEEMRNNKAASKRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS21 EENSQYLSSRKNESSVAKNYEQDPEIVCTIPSKFQETQHSEITPSQDEEMRNNKAASKRV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 SLHKNEAMEPNNILEECTVLKSLSSVVFDDPIDKLPEGCSSMETNIKISIAERAKPEMSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS21 SLHKNEAMEPNNILEECTVLKSLSSVVFDDPIDKLPEGCSSMETNIKISIAERAKPEMSR
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 MVPLIHITFPVDGSPKEPVIAKPSLQTRKGTIHNNHSVNIPVHQENDKHKMNSHRSKLDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS21 MVPLIHITFPVDGSPKEPVIAKPSLQTRKGTIHNNHSVNIPVHQENDKHKMNSHRSKLDS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 KTKTSKKTPQNFVISTEGPIKPTMHKTSIKTQIFPALGLVDPRPWQLPRFQKKMPQIAKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS21 KTKTSKKTPQNFVISTEGPIKPTMHKTSIKTQIFPALGLVDPRPWQLPRFQKKMPQIAKK
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 QSTHRTQKPKKQSFPCICKNPGTQKSCVPLSVQPTEPRLNYLDLKYSDMFKEINSTANGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS21 QSTHRTQKPKKQSFPCICKNPGTQKSCVPLSVQPTEPRLNYLDLKYSDMFKEINSTANGP
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 GIYEMFGTPVYCHVRETERDENTYYREICSAPSGRRITNKCRSSHSERKSNIRTRLSQKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS21 GIYEMFGTPVYCHVRETERDENTYYREICSAPSGRRITNKCRSSHSERKSNIRTRLSQKK
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 THMKCPKTSFGIKQEHKVLISKEKSSKAVHSNLHDIENGDGISEPDWQIKSSGNEFLSSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS21 THMKCPKTSFGIKQEHKVLISKEKSSKAVHSNLHDIENGDGISEPDWQIKSSGNEFLSSK
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE3 DEIHPMNLAQTPEQSMKQNEFPPVSDLSIVEEVSMEESTGDRDISNNQILTTSLRDLQEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS21 DEIHPMNLAQTPEQSMKQNEFPPVSDLSIVEEVSMEESTGDRDISNNQILTTSLRDLQEL
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE3 EELHHQIPFIPSEDSWAVPSEKNSNKYVQQEKQNTASLSKVNASRILTNDLEFDSVSDHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS21 EELHHQIPFIPSEDSWAVPSEKNSNKYVQQEKQNTASLSKVNASRILTNDLEFDSVSDHS
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE3 KTLTNFSFQAKQESASSQTYQYWVHYLDHDSLANKSITYQMFGKTLSGTNSISQEIMDSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS21 KTLTNFSFQAKQESASSQTYQYWVHYLDHDSLANKSITYQMFGKTLSGTNSISQEIMDSV
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE3 NNEELTDELLGCLAAELLALDEKDNNSCQKMANETDPENLNLVLRWRGSTPKEMGRETTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS21 NNEELTDELLGCLAAELLALDEKDNNSCQKMANETDPENLNLVLRWRGSTPKEMGRETTK
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE3 VKIQRHSSGLRIYDREEKFLISNEKKIFSENSLKSEEPILWTKGEILGKGAYGTVYCGLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS21 VKIQRHSSGLRIYDREEKFLISNEKKIFSENSLKSEEPILWTKGEILGKGAYGTVYCGLT
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE3 SQGQLIAVKQVALDTSNKLAAEKEYRKLQEEVDLLKALKHVNIVAYLGTCLQENTVSIFM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS21 SQGQLIAVKQVALDTSNKLAAEKEYRKLQEEVDLLKALKHVNIVAYLGTCLQENTVSIFM
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE3 EFVPGGSISSIINRFGPLPEMVFCKYTKQILQGVAYLHENCVVHRDIKGNNVMLMPTGII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS21 EFVPGGSISSIINRFGPLPEMVFCKYTKQILQGVAYLHENCVVHRDIKGNNVMLMPTGII
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE3 KLIDFGCARRLAWAGLNGTHSDMLKSMHGTPYWMAPEVINESGYGRKSDIWSIGCTVFEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS21 KLIDFGCARRLAWAGLNGTHSDMLKSMHGTPYWMAPEVINESGYGRKSDIWSIGCTVFEM
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE3 ATGKPPLASMDRMAAMFYIGAHRGLMPPLPDHFSENAADFVRMCLTRDQHERPSALQLLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS21 ATGKPPLASMDRMAAMFYIGAHRGLMPPLPDHFSENAADFVRMCLTRDQHERPSALQLLK
1270 1280 1290 1300 1310 1320
pF1KE3 HSFLERSH
::::::::
CCDS21 HSFLERSH
>>CCDS63020.1 MAP3K19 gene_id:80122|Hs108|chr2 (1215 aa)
initn: 7604 init1: 7604 opt: 7604 Z-score: 4926.9 bits: 923.8 E(32554): 0
Smith-Waterman score: 7881; 91.5% identity (91.5% similar) in 1328 aa overlap (1-1328:1-1215)
10 20 30 40 50 60
pF1KE3 MSSMPKPERHAESLLDICHDTNSSPTDLMTVTKNQNIILQSISRSEEFDQDGDCSHSTLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS63 MSSMPKPERHAESLLDICHDTNSSPTDLMTVTKNQNIILQSISRSEEFDQDGDCSHSTLV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 NEEEDPSGGRQDWQPRTEGVEITVTFPRDVSPPQEMSQEDLKEKNLINSSLQEWAQAHAV
::::::::::::::::::
CCDS63 NEEEDPSGGRQDWQPRTE------------------------------------------
70
130 140 150 160 170 180
pF1KE3 SHPNEIETVELRKKKLTMRPLVLQKEESSRELCNVNLGFLLPRSCLELNISKSVTREDAP
CCDS63 ------------------------------------------------------------
190 200 210 220 230 240
pF1KE3 HFLKEQQRKSEEFSTSHMKYSGRSIKFLLPPLSLLPTRSGVLTIPQNHKFPKEKERNIPS
:::::::::::::::::::::::::::::::::::::::::::::::::
CCDS63 -----------EFSTSHMKYSGRSIKFLLPPLSLLPTRSGVLTIPQNHKFPKEKERNIPS
80 90 100 110 120
250 260 270 280 290 300
pF1KE3 LTSFVPKLSVSVRQSDELSPSNEPPGALVKSLMDPTLRSSDGFIWSRNMCSFPKTNHHRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS63 LTSFVPKLSVSVRQSDELSPSNEPPGALVKSLMDPTLRSSDGFIWSRNMCSFPKTNHHRQ
130 140 150 160 170 180
310 320 330 340 350 360
pF1KE3 CLEKEENWKSKEIEECNKIEITHFEKGQSLVSFENLKEGNIPAVREEDIDCHGSKTRKPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS63 CLEKEENWKSKEIEECNKIEITHFEKGQSLVSFENLKEGNIPAVREEDIDCHGSKTRKPE
190 200 210 220 230 240
370 380 390 400 410 420
pF1KE3 EENSQYLSSRKNESSVAKNYEQDPEIVCTIPSKFQETQHSEITPSQDEEMRNNKAASKRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS63 EENSQYLSSRKNESSVAKNYEQDPEIVCTIPSKFQETQHSEITPSQDEEMRNNKAASKRV
250 260 270 280 290 300
430 440 450 460 470 480
pF1KE3 SLHKNEAMEPNNILEECTVLKSLSSVVFDDPIDKLPEGCSSMETNIKISIAERAKPEMSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS63 SLHKNEAMEPNNILEECTVLKSLSSVVFDDPIDKLPEGCSSMETNIKISIAERAKPEMSR
310 320 330 340 350 360
490 500 510 520 530 540
pF1KE3 MVPLIHITFPVDGSPKEPVIAKPSLQTRKGTIHNNHSVNIPVHQENDKHKMNSHRSKLDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS63 MVPLIHITFPVDGSPKEPVIAKPSLQTRKGTIHNNHSVNIPVHQENDKHKMNSHRSKLDS
370 380 390 400 410 420
550 560 570 580 590 600
pF1KE3 KTKTSKKTPQNFVISTEGPIKPTMHKTSIKTQIFPALGLVDPRPWQLPRFQKKMPQIAKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS63 KTKTSKKTPQNFVISTEGPIKPTMHKTSIKTQIFPALGLVDPRPWQLPRFQKKMPQIAKK
430 440 450 460 470 480
610 620 630 640 650 660
pF1KE3 QSTHRTQKPKKQSFPCICKNPGTQKSCVPLSVQPTEPRLNYLDLKYSDMFKEINSTANGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS63 QSTHRTQKPKKQSFPCICKNPGTQKSCVPLSVQPTEPRLNYLDLKYSDMFKEINSTANGP
490 500 510 520 530 540
670 680 690 700 710 720
pF1KE3 GIYEMFGTPVYCHVRETERDENTYYREICSAPSGRRITNKCRSSHSERKSNIRTRLSQKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS63 GIYEMFGTPVYCHVRETERDENTYYREICSAPSGRRITNKCRSSHSERKSNIRTRLSQKK
550 560 570 580 590 600
730 740 750 760 770 780
pF1KE3 THMKCPKTSFGIKQEHKVLISKEKSSKAVHSNLHDIENGDGISEPDWQIKSSGNEFLSSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS63 THMKCPKTSFGIKQEHKVLISKEKSSKAVHSNLHDIENGDGISEPDWQIKSSGNEFLSSK
610 620 630 640 650 660
790 800 810 820 830 840
pF1KE3 DEIHPMNLAQTPEQSMKQNEFPPVSDLSIVEEVSMEESTGDRDISNNQILTTSLRDLQEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS63 DEIHPMNLAQTPEQSMKQNEFPPVSDLSIVEEVSMEESTGDRDISNNQILTTSLRDLQEL
670 680 690 700 710 720
850 860 870 880 890 900
pF1KE3 EELHHQIPFIPSEDSWAVPSEKNSNKYVQQEKQNTASLSKVNASRILTNDLEFDSVSDHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS63 EELHHQIPFIPSEDSWAVPSEKNSNKYVQQEKQNTASLSKVNASRILTNDLEFDSVSDHS
730 740 750 760 770 780
910 920 930 940 950 960
pF1KE3 KTLTNFSFQAKQESASSQTYQYWVHYLDHDSLANKSITYQMFGKTLSGTNSISQEIMDSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS63 KTLTNFSFQAKQESASSQTYQYWVHYLDHDSLANKSITYQMFGKTLSGTNSISQEIMDSV
790 800 810 820 830 840
970 980 990 1000 1010 1020
pF1KE3 NNEELTDELLGCLAAELLALDEKDNNSCQKMANETDPENLNLVLRWRGSTPKEMGRETTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS63 NNEELTDELLGCLAAELLALDEKDNNSCQKMANETDPENLNLVLRWRGSTPKEMGRETTK
850 860 870 880 890 900
1030 1040 1050 1060 1070 1080
pF1KE3 VKIQRHSSGLRIYDREEKFLISNEKKIFSENSLKSEEPILWTKGEILGKGAYGTVYCGLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS63 VKIQRHSSGLRIYDREEKFLISNEKKIFSENSLKSEEPILWTKGEILGKGAYGTVYCGLT
910 920 930 940 950 960
1090 1100 1110 1120 1130 1140
pF1KE3 SQGQLIAVKQVALDTSNKLAAEKEYRKLQEEVDLLKALKHVNIVAYLGTCLQENTVSIFM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS63 SQGQLIAVKQVALDTSNKLAAEKEYRKLQEEVDLLKALKHVNIVAYLGTCLQENTVSIFM
970 980 990 1000 1010 1020
1150 1160 1170 1180 1190 1200
pF1KE3 EFVPGGSISSIINRFGPLPEMVFCKYTKQILQGVAYLHENCVVHRDIKGNNVMLMPTGII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS63 EFVPGGSISSIINRFGPLPEMVFCKYTKQILQGVAYLHENCVVHRDIKGNNVMLMPTGII
1030 1040 1050 1060 1070 1080
1210 1220 1230 1240 1250 1260
pF1KE3 KLIDFGCARRLAWAGLNGTHSDMLKSMHGTPYWMAPEVINESGYGRKSDIWSIGCTVFEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS63 KLIDFGCARRLAWAGLNGTHSDMLKSMHGTPYWMAPEVINESGYGRKSDIWSIGCTVFEM
1090 1100 1110 1120 1130 1140
1270 1280 1290 1300 1310 1320
pF1KE3 ATGKPPLASMDRMAAMFYIGAHRGLMPPLPDHFSENAADFVRMCLTRDQHERPSALQLLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS63 ATGKPPLASMDRMAAMFYIGAHRGLMPPLPDHFSENAADFVRMCLTRDQHERPSALQLLK
1150 1160 1170 1180 1190 1200
pF1KE3 HSFLERSH
::::::::
CCDS63 HSFLERSH
1210
>>CCDS33293.1 MAP3K19 gene_id:80122|Hs108|chr2 (510 aa)
initn: 2053 init1: 2053 opt: 2055 Z-score: 1348.6 bits: 260.5 E(32554): 8.5e-69
Smith-Waterman score: 2062; 77.8% identity (84.7% similar) in 424 aa overlap (911-1328:102-510)
890 900 910 920 930
pF1KE3 VNASRILTNDLEFDSVSDHSKTLTNFSFQAKQESASSQTYQYWV--HYLDHDSLANKSIT
:... ... : :. : ..: :. :
CCDS33 DWQPRTEGVEITVTFPRDVSPPQEMSQEDLKEKNLINSSLQEWAQAHAVSH---PNEIET
80 90 100 110 120
940 950 960 970 980 990
pF1KE3 YQMFGKTLSGTNSISQEIMDSVNNEELTDELLGCLAAELLALDEKDNNSCQKMANETDPE
.. : :. . :. :: . :: . . :: . . : .... : :.
CCDS33 VELRKKKLTMRPLVLQK-------EESSRELCNVNLGFLLPRSCLELNISKSVTREDAPH
130 140 150 160 170 180
1000 1010 1020 1030 1040 1050
pF1KE3 NLNLVLR----WRGSTPKEMGRETTKVKIQRHSSGLRIYDREEKFLISNEKKIFSENSLK
:. : . : : :: .:.::::::::::::::::::::::::::::::
CCDS33 FLKEQQRKSEEFSTSHMKYSGR-----SIKRHSSGLRIYDREEKFLISNEKKIFSENSLK
190 200 210 220 230
1060 1070 1080 1090 1100 1110
pF1KE3 SEEPILWTKGEILGKGAYGTVYCGLTSQGQLIAVKQVALDTSNKLAAEKEYRKLQEEVDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 SEEPILWTKGEILGKGAYGTVYCGLTSQGQLIAVKQVALDTSNKLAAEKEYRKLQEEVDL
240 250 260 270 280 290
1120 1130 1140 1150 1160 1170
pF1KE3 LKALKHVNIVAYLGTCLQENTVSIFMEFVPGGSISSIINRFGPLPEMVFCKYTKQILQGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 LKALKHVNIVAYLGTCLQENTVSIFMEFVPGGSISSIINRFGPLPEMVFCKYTKQILQGV
300 310 320 330 340 350
1180 1190 1200 1210 1220 1230
pF1KE3 AYLHENCVVHRDIKGNNVMLMPTGIIKLIDFGCARRLAWAGLNGTHSDMLKSMHGTPYWM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 AYLHENCVVHRDIKGNNVMLMPTGIIKLIDFGCARRLAWAGLNGTHSDMLKSMHGTPYWM
360 370 380 390 400 410
1240 1250 1260 1270 1280 1290
pF1KE3 APEVINESGYGRKSDIWSIGCTVFEMATGKPPLASMDRMAAMFYIGAHRGLMPPLPDHFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 APEVINESGYGRKSDIWSIGCTVFEMATGKPPLASMDRMAAMFYIGAHRGLMPPLPDHFS
420 430 440 450 460 470
1300 1310 1320
pF1KE3 ENAADFVRMCLTRDQHERPSALQLLKHSFLERSH
::::::::::::::::::::::::::::::::::
CCDS33 ENAADFVRMCLTRDQHERPSALQLLKHSFLERSH
480 490 500 510
>--
initn: 687 init1: 687 opt: 687 Z-score: 465.2 bits: 97.0 E(32554): 1.4e-19
Smith-Waterman score: 687; 100.0% identity (100.0% similar) in 101 aa overlap (1-101:1-101)
10 20 30 40 50 60
pF1KE3 MSSMPKPERHAESLLDICHDTNSSPTDLMTVTKNQNIILQSISRSEEFDQDGDCSHSTLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS33 MSSMPKPERHAESLLDICHDTNSSPTDLMTVTKNQNIILQSISRSEEFDQDGDCSHSTLV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 NEEEDPSGGRQDWQPRTEGVEITVTFPRDVSPPQEMSQEDLKEKNLINSSLQEWAQAHAV
:::::::::::::::::::::::::::::::::::::::::
CCDS33 NEEEDPSGGRQDWQPRTEGVEITVTFPRDVSPPQEMSQEDLKEKNLINSSLQEWAQAHAV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 SHPNEIETVELRKKKLTMRPLVLQKEESSRELCNVNLGFLLPRSCLELNISKSVTREDAP
CCDS33 SHPNEIETVELRKKKLTMRPLVLQKEESSRELCNVNLGFLLPRSCLELNISKSVTREDAP
130 140 150 160 170 180
>>CCDS63021.1 MAP3K19 gene_id:80122|Hs108|chr2 (460 aa)
initn: 3072 init1: 1723 opt: 1731 Z-score: 1140.0 bits: 221.7 E(32554): 3.5e-57
Smith-Waterman score: 1731; 92.5% identity (96.1% similar) in 281 aa overlap (1048-1328:183-460)
1020 1030 1040 1050 1060 1070
pF1KE3 TTKVKIQRHSSGLRIYDREEKFLISNEKKIFSENSLKSEEPILWTKGEILGKGAYGTVYC
..:.. :::: .. ... .: :::
CCDS63 CNVNLGFLLPRSCLELNISKSVTREDAPHFLKEQQRKSEE---FSTSHMKYSGRSIKVYC
160 170 180 190 200
1080 1090 1100 1110 1120 1130
pF1KE3 GLTSQGQLIAVKQVALDTSNKLAAEKEYRKLQEEVDLLKALKHVNIVAYLGTCLQENTVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS63 GLTSQGQLIAVKQVALDTSNKLAAEKEYRKLQEEVDLLKALKHVNIVAYLGTCLQENTVS
210 220 230 240 250 260
1140 1150 1160 1170 1180 1190
pF1KE3 IFMEFVPGGSISSIINRFGPLPEMVFCKYTKQILQGVAYLHENCVVHRDIKGNNVMLMPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS63 IFMEFVPGGSISSIINRFGPLPEMVFCKYTKQILQGVAYLHENCVVHRDIKGNNVMLMPT
270 280 290 300 310 320
1200 1210 1220 1230 1240 1250
pF1KE3 GIIKLIDFGCARRLAWAGLNGTHSDMLKSMHGTPYWMAPEVINESGYGRKSDIWSIGCTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS63 GIIKLIDFGCARRLAWAGLNGTHSDMLKSMHGTPYWMAPEVINESGYGRKSDIWSIGCTV
330 340 350 360 370 380
1260 1270 1280 1290 1300 1310
pF1KE3 FEMATGKPPLASMDRMAAMFYIGAHRGLMPPLPDHFSENAADFVRMCLTRDQHERPSALQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS63 FEMATGKPPLASMDRMAAMFYIGAHRGLMPPLPDHFSENAADFVRMCLTRDQHERPSALQ
390 400 410 420 430 440
1320
pF1KE3 LLKHSFLERSH
:::::::::::
CCDS63 LLKHSFLERSH
450 460
>--
initn: 1212 init1: 1212 opt: 1212 Z-score: 804.8 bits: 159.7 E(32554): 1.6e-38
Smith-Waterman score: 1212; 100.0% identity (100.0% similar) in 182 aa overlap (1-182:1-182)
10 20 30 40 50 60
pF1KE3 MSSMPKPERHAESLLDICHDTNSSPTDLMTVTKNQNIILQSISRSEEFDQDGDCSHSTLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS63 MSSMPKPERHAESLLDICHDTNSSPTDLMTVTKNQNIILQSISRSEEFDQDGDCSHSTLV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 NEEEDPSGGRQDWQPRTEGVEITVTFPRDVSPPQEMSQEDLKEKNLINSSLQEWAQAHAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS63 NEEEDPSGGRQDWQPRTEGVEITVTFPRDVSPPQEMSQEDLKEKNLINSSLQEWAQAHAV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 SHPNEIETVELRKKKLTMRPLVLQKEESSRELCNVNLGFLLPRSCLELNISKSVTREDAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS63 SHPNEIETVELRKKKLTMRPLVLQKEESSRELCNVNLGFLLPRSCLELNISKSVTREDAP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 HFLKEQQRKSEEFSTSHMKYSGRSIKFLLPPLSLLPTRSGVLTIPQNHKFPKEKERNIPS
::
CCDS63 HFLKEQQRKSEEFSTSHMKYSGRSIKVYCGLTSQGQLIAVKQVALDTSNKLAAEKEYRKL
190 200 210 220 230 240
>>CCDS63022.1 MAP3K19 gene_id:80122|Hs108|chr2 (462 aa)
initn: 2848 init1: 1499 opt: 1503 Z-score: 992.7 bits: 194.5 E(32554): 5.7e-49
Smith-Waterman score: 1656; 66.5% identity (73.3% similar) in 424 aa overlap (911-1328:102-462)
890 900 910 920 930
pF1KE3 VNASRILTNDLEFDSVSDHSKTLTNFSFQAKQESASSQTYQYWV--HYLDHDSLANKSIT
:... ... : :. : ..: :. :
CCDS63 DWQPRTEGVEITVTFPRDVSPPQEMSQEDLKEKNLINSSLQEWAQAHAVSH---PNEIET
80 90 100 110 120
940 950 960 970 980 990
pF1KE3 YQMFGKTLSGTNSISQEIMDSVNNEELTDELLGCLAAELLALDEKDNNSCQKMANETDPE
.. : :. . :. :: . :: . . :: . . : .... : :.
CCDS63 VELRKKKLTMRPLVLQK-------EESSRELCNVNLGFLLPRSCLELNISKSVTREDAPH
130 140 150 160 170 180
1000 1010 1020 1030 1040 1050
pF1KE3 NLNLVLR----WRGSTPKEMGRETTKVKIQRHSSGLRIYDREEKFLISNEKKIFSENSLK
:. : . : : :: .:.::::::::::::::::::::::::::::::
CCDS63 FLKEQQRKSEEFSTSHMKYSGR-----SIKRHSSGLRIYDREEKFLISNEKKIFSENSLK
190 200 210 220 230
1060 1070 1080 1090 1100 1110
pF1KE3 SEEPILWTKGEILGKGAYGTVYCGLTSQGQLIAVKQVALDTSNKLAAEKEYRKLQEEVDL
::::::::: :::
CCDS63 SEEPILWTK------------------------------------------------VDL
240
1120 1130 1140 1150 1160 1170
pF1KE3 LKALKHVNIVAYLGTCLQENTVSIFMEFVPGGSISSIINRFGPLPEMVFCKYTKQILQGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS63 LKALKHVNIVAYLGTCLQENTVSIFMEFVPGGSISSIINRFGPLPEMVFCKYTKQILQGV
250 260 270 280 290 300
1180 1190 1200 1210 1220 1230
pF1KE3 AYLHENCVVHRDIKGNNVMLMPTGIIKLIDFGCARRLAWAGLNGTHSDMLKSMHGTPYWM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS63 AYLHENCVVHRDIKGNNVMLMPTGIIKLIDFGCARRLAWAGLNGTHSDMLKSMHGTPYWM
310 320 330 340 350 360
1240 1250 1260 1270 1280 1290
pF1KE3 APEVINESGYGRKSDIWSIGCTVFEMATGKPPLASMDRMAAMFYIGAHRGLMPPLPDHFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS63 APEVINESGYGRKSDIWSIGCTVFEMATGKPPLASMDRMAAMFYIGAHRGLMPPLPDHFS
370 380 390 400 410 420
1300 1310 1320
pF1KE3 ENAADFVRMCLTRDQHERPSALQLLKHSFLERSH
::::::::::::::::::::::::::::::::::
CCDS63 ENAADFVRMCLTRDQHERPSALQLLKHSFLERSH
430 440 450 460
>--
initn: 687 init1: 687 opt: 687 Z-score: 465.8 bits: 97.0 E(32554): 1.3e-19
Smith-Waterman score: 687; 100.0% identity (100.0% similar) in 101 aa overlap (1-101:1-101)
10 20 30 40 50 60
pF1KE3 MSSMPKPERHAESLLDICHDTNSSPTDLMTVTKNQNIILQSISRSEEFDQDGDCSHSTLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS63 MSSMPKPERHAESLLDICHDTNSSPTDLMTVTKNQNIILQSISRSEEFDQDGDCSHSTLV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 NEEEDPSGGRQDWQPRTEGVEITVTFPRDVSPPQEMSQEDLKEKNLINSSLQEWAQAHAV
:::::::::::::::::::::::::::::::::::::::::
CCDS63 NEEEDPSGGRQDWQPRTEGVEITVTFPRDVSPPQEMSQEDLKEKNLINSSLQEWAQAHAV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 SHPNEIETVELRKKKLTMRPLVLQKEESSRELCNVNLGFLLPRSCLELNISKSVTREDAP
CCDS63 SHPNEIETVELRKKKLTMRPLVLQKEESSRELCNVNLGFLLPRSCLELNISKSVTREDAP
130 140 150 160 170 180
>>CCDS82186.1 MAP3K3 gene_id:4215|Hs108|chr17 (622 aa)
initn: 763 init1: 295 opt: 807 Z-score: 541.6 bits: 111.5 E(32554): 7.6e-24
Smith-Waterman score: 807; 45.0% identity (70.1% similar) in 298 aa overlap (1030-1323:331-617)
1000 1010 1020 1030 1040 1050
pF1KE3 LNLVLRWRGSTPKEMGRETTKVKIQRHSSGLRIYDREEKFLISNEKKIFSENSLKSEEPI
:: : :. . .. :... ... ::
CCDS82 LFTLVPSSRSLSTNGENMGLAVQYLDPRGRLRSADSENALSVQ-ERNVPTKSP---SAPI
310 320 330 340 350
1060 1070 1080 1090 1100 1110
pF1KE3 LWTKGEILGKGAYGTVY-CGLTSQGQLIAVKQVALDTSNKLAAEKEYRKLQEEVDLLKAL
: .:..::.::.: :: : .. :. .: ::: .: .. . :: :. :..::: :
CCDS82 NWRRGKLLGQGAFGRVYLCYDVDTGRELASKQVQFDPDSP-ETSKEVSALECEIQLLKNL
360 370 380 390 400 410
1120 1130 1140 1150 1160 1170
pF1KE3 KHVNIVAYLGTCLQ---ENTVSIFMEFVPGGSISSIINRFGPLPEMVFCKYTKQILQGVA
.: :: : : ::. :.:..::::..::::... .. .: : : : :::.:::.:..
CCDS82 QHERIVQYYG-CLRDRAEKTLTIFMEYMPGGSVKDQLKAYGALTESVTRKYTRQILEGMS
420 430 440 450 460 470
1180 1190 1200 1210 1220 1230
pF1KE3 YLHENCVVHRDIKGNNVMLMPTGIIKLIDFGCARRLAWAGLNGTHSDMLKSMHGTPYWMA
::: : .::::::: :.. .: .:: ::: ..:: ..:: ..:. ::::::.
CCDS82 YLHSNMIVHRDIKGANILRDSAGNVKLGDFGASKRLQTICMSGTG---MRSVTGTPYWMS
480 490 500 510 520 530
1240 1250 1260 1270 1280 1290
pF1KE3 PEVINESGYGRKSDIWSIGCTVFEMATGKPPLASMDRMAAMFYIGAHRGLMPPLPDHFSE
::::. :::::.:.::.:::: :: : ::: : .. :::.: : : . : ::.:.::
CCDS82 PEVISGEGYGRKADVWSLGCTVVEMLTEKPPWAEYEAMAAIFKI-ATQPTNPQLPSHISE
540 550 560 570 580 590
1300 1310 1320
pF1KE3 NAADFVRMCLTRDQHERPSALQLLKHSFLERSH
.. ::.: .. . ..:::: .:: : :
CCDS82 HGRDFLRRIFV-EARQRPSAEELLTHHFAQLMY
600 610 620
>>CCDS32702.1 MAP3K3 gene_id:4215|Hs108|chr17 (626 aa)
initn: 763 init1: 295 opt: 807 Z-score: 541.6 bits: 111.5 E(32554): 7.6e-24
Smith-Waterman score: 807; 45.0% identity (70.1% similar) in 298 aa overlap (1030-1323:335-621)
1000 1010 1020 1030 1040 1050
pF1KE3 LNLVLRWRGSTPKEMGRETTKVKIQRHSSGLRIYDREEKFLISNEKKIFSENSLKSEEPI
:: : :. . .. :... ... ::
CCDS32 LFTLVPSSRSLSTNGENMGLAVQYLDPRGRLRSADSENALSVQ-ERNVPTKSP---SAPI
310 320 330 340 350 360
1060 1070 1080 1090 1100 1110
pF1KE3 LWTKGEILGKGAYGTVY-CGLTSQGQLIAVKQVALDTSNKLAAEKEYRKLQEEVDLLKAL
: .:..::.::.: :: : .. :. .: ::: .: .. . :: :. :..::: :
CCDS32 NWRRGKLLGQGAFGRVYLCYDVDTGRELASKQVQFDPDSP-ETSKEVSALECEIQLLKNL
370 380 390 400 410
1120 1130 1140 1150 1160 1170
pF1KE3 KHVNIVAYLGTCLQ---ENTVSIFMEFVPGGSISSIINRFGPLPEMVFCKYTKQILQGVA
.: :: : : ::. :.:..::::..::::... .. .: : : : :::.:::.:..
CCDS32 QHERIVQYYG-CLRDRAEKTLTIFMEYMPGGSVKDQLKAYGALTESVTRKYTRQILEGMS
420 430 440 450 460 470
1180 1190 1200 1210 1220 1230
pF1KE3 YLHENCVVHRDIKGNNVMLMPTGIIKLIDFGCARRLAWAGLNGTHSDMLKSMHGTPYWMA
::: : .::::::: :.. .: .:: ::: ..:: ..:: ..:. ::::::.
CCDS32 YLHSNMIVHRDIKGANILRDSAGNVKLGDFGASKRLQTICMSGTG---MRSVTGTPYWMS
480 490 500 510 520 530
1240 1250 1260 1270 1280 1290
pF1KE3 PEVINESGYGRKSDIWSIGCTVFEMATGKPPLASMDRMAAMFYIGAHRGLMPPLPDHFSE
::::. :::::.:.::.:::: :: : ::: : .. :::.: : : . : ::.:.::
CCDS32 PEVISGEGYGRKADVWSLGCTVVEMLTEKPPWAEYEAMAAIFKI-ATQPTNPQLPSHISE
540 550 560 570 580 590
1300 1310 1320
pF1KE3 NAADFVRMCLTRDQHERPSALQLLKHSFLERSH
.. ::.: .. . ..:::: .:: : :
CCDS32 HGRDFLRRIFV-EARQRPSAEELLTHHFAQLMY
600 610 620
>>CCDS32701.1 MAP3K3 gene_id:4215|Hs108|chr17 (657 aa)
initn: 763 init1: 295 opt: 807 Z-score: 541.3 bits: 111.5 E(32554): 7.9e-24
Smith-Waterman score: 807; 45.0% identity (70.1% similar) in 298 aa overlap (1030-1323:366-652)
1000 1010 1020 1030 1040 1050
pF1KE3 LNLVLRWRGSTPKEMGRETTKVKIQRHSSGLRIYDREEKFLISNEKKIFSENSLKSEEPI
:: : :. . .. :... ... ::
CCDS32 LFTLVPSSRSLSTNGENMGLAVQYLDPRGRLRSADSENALSVQ-ERNVPTKSP---SAPI
340 350 360 370 380 390
1060 1070 1080 1090 1100 1110
pF1KE3 LWTKGEILGKGAYGTVY-CGLTSQGQLIAVKQVALDTSNKLAAEKEYRKLQEEVDLLKAL
: .:..::.::.: :: : .. :. .: ::: .: .. . :: :. :..::: :
CCDS32 NWRRGKLLGQGAFGRVYLCYDVDTGRELASKQVQFDPDSP-ETSKEVSALECEIQLLKNL
400 410 420 430 440 450
1120 1130 1140 1150 1160 1170
pF1KE3 KHVNIVAYLGTCLQ---ENTVSIFMEFVPGGSISSIINRFGPLPEMVFCKYTKQILQGVA
.: :: : : ::. :.:..::::..::::... .. .: : : : :::.:::.:..
CCDS32 QHERIVQYYG-CLRDRAEKTLTIFMEYMPGGSVKDQLKAYGALTESVTRKYTRQILEGMS
460 470 480 490 500
1180 1190 1200 1210 1220 1230
pF1KE3 YLHENCVVHRDIKGNNVMLMPTGIIKLIDFGCARRLAWAGLNGTHSDMLKSMHGTPYWMA
::: : .::::::: :.. .: .:: ::: ..:: ..:: ..:. ::::::.
CCDS32 YLHSNMIVHRDIKGANILRDSAGNVKLGDFGASKRLQTICMSGTG---MRSVTGTPYWMS
510 520 530 540 550 560
1240 1250 1260 1270 1280 1290
pF1KE3 PEVINESGYGRKSDIWSIGCTVFEMATGKPPLASMDRMAAMFYIGAHRGLMPPLPDHFSE
::::. :::::.:.::.:::: :: : ::: : .. :::.: : : . : ::.:.::
CCDS32 PEVISGEGYGRKADVWSLGCTVVEMLTEKPPWAEYEAMAAIFKI-ATQPTNPQLPSHISE
570 580 590 600 610 620
1300 1310 1320
pF1KE3 NAADFVRMCLTRDQHERPSALQLLKHSFLERSH
.. ::.: .. . ..:::: .:: : :
CCDS32 HGRDFLRRIFV-EARQRPSAEELLTHHFAQLMY
630 640 650
>>CCDS46404.1 MAP3K2 gene_id:10746|Hs108|chr2 (619 aa)
initn: 666 init1: 314 opt: 797 Z-score: 535.2 bits: 110.3 E(32554): 1.7e-23
Smith-Waterman score: 797; 48.6% identity (68.9% similar) in 280 aa overlap (1049-1324:344-616)
1020 1030 1040 1050 1060 1070
pF1KE3 TKVKIQRHSSGLRIYDREEKFLISNEKKIFSENSLKSEEPILWTKGEILGKGAYGTVY-C
: : . . : : :..::.::.: :: :
CCDS46 SSIFTPEYDDSRIRRRGSDIDNPTLTVMDISPPSRSPRAPTNWRLGKLLGQGAFGRVYLC
320 330 340 350 360 370
1080 1090 1100 1110 1120 1130
pF1KE3 GLTSQGQLIAVKQVALDTSNKLAAEKEYRKLQEEVDLLKALKHVNIVAYLGTCL---QEN
.. :. .::::: .: .. . :: :. :..::: : : :: : : :: ::.
CCDS46 YDVDTGRELAVKQVQFDPDSP-ETSKEVNALECEIQLLKNLLHERIVQYYG-CLRDPQEK
380 390 400 410 420 430
1140 1150 1160 1170 1180 1190
pF1KE3 TVSIFMEFVPGGSISSIINRFGPLPEMVFCKYTKQILQGVAYLHENCVVHRDIKGNNVML
:.:::::..:::::.. .. .: : : : :::.:::.:: ::: : .::::::: :..
CCDS46 TLSIFMEYMPGGSIKDQLKAYGALTENVTRKYTRQILEGVHYLHSNMIVHRDIKGANILR
440 450 460 470 480 490
1200 1210 1220 1230 1240 1250
pF1KE3 MPTGIIKLIDFGCARRLAWAGLNGTHSDMLKSMHGTPYWMAPEVINESGYGRKSDIWSIG
:: .:: ::: ..:: :.:: .::. ::::::.::::. :::::.::::..
CCDS46 DSTGNVKLGDFGASKRLQTICLSGTG---MKSVTGTPYWMSPEVISGEGYGRKADIWSVA
500 510 520 530 540
1260 1270 1280 1290 1300 1310
pF1KE3 CTVFEMATGKPPLASMDRMAAMFYIGAHRGLMPPLPDHFSENAADFVRMCLTRDQHERPS
::: :: : ::: : .. :::.: : : . : :: : :. . ::.. .. . . :::
CCDS46 CTVVEMLTEKPPWAEFEAMAAIFKI-ATQPTNPKLPPHVSDYTRDFLKRIFV-EAKLRPS
550 560 570 580 590 600
1320
pF1KE3 ALQLLKHSFLERSH
: .::.: :.
CCDS46 ADELLRHMFVHYH
610
>>CCDS35212.2 MAP3K15 gene_id:389840|Hs108|chrX (1313 aa)
initn: 659 init1: 225 opt: 684 Z-score: 457.9 bits: 97.0 E(32554): 3.5e-19
Smith-Waterman score: 684; 42.7% identity (71.2% similar) in 267 aa overlap (1066-1326:657-910)
1040 1050 1060 1070 1080 1090
pF1KE3 EEKFLISNEKKIFSENSLKSEEPILWTKGEILGKGAYGTVYCGLTSQGQL-IAVKQVALD
.::::.:: :: : ..:. ::.:..
CCDS35 TAGSTVELEGETDGDTLEYEYDHDANGERVVLGKGTYGIVYAGRDLSNQVRIAIKEIPER
630 640 650 660 670 680
1100 1110 1120 1130 1140 1150
pF1KE3 TSNKLAAEKEYRKLQEEVDLLKALKHVNIVAYLGTCLQENTVSIFMEFVPGGSISSII-N
: . . :.::. : : ::: ::: :::. ... ..:::: :::::.:... .
CCDS35 DS------RYSQPLHEEIALHKYLKHRNIVQYLGSVSENGYIKIFMEQVPGGSLSALLRS
690 700 710 720 730 740
1160 1170 1180 1190 1200 1210
pF1KE3 RFGPLPEMVFCKYTKQILQGVAYLHENCVVHRDIKGNNVMLMP-TGIIKLIDFGCARRLA
..::. : .. ::::::.:. ::::: .:::::::.::.. .:..:. ::: ..::
CCDS35 KWGPMKEPTIKFYTKQILEGLKYLHENQIVHRDIKGDNVLVNTYSGVVKISDFGTSKRL-
750 760 770 780 790
1220 1230 1240 1250 1260 1270
pF1KE3 WAGLNGTHSDMLKSMHGTPYWMAPEVINES--GYGRKSDIWSIGCTVFEMATGKPPLASM
::.: ... :: .::::.:... ::: .::::.:::..::::.:::. .
CCDS35 -AGVNPC----TETFTGTLQYMAPEIIDQGPRGYGAPADIWSLGCTIIEMATSKPPFHEL
800 810 820 830 840 850
1280 1290 1300 1310 1320
pF1KE3 DR-MAAMFYIGAHRGLMPPLPDHFSENAADFVRMCLTRDQHERPSALQLLKHSFLERSH
. .:::: .: . . : .:. .: .: :. :. : :.: .. .::...::..
CCDS35 GEPQAAMFKVGMFK-IHPEIPEALSAEARAFILSCFEPDPHKRATTAELLREGFLRQVNK
860 870 880 890 900 910
CCDS35 GKKNRIAFKPSEGPRGVVLALPTQGEPMATSSSEHGSVSPDSDAQPDALFERTRAPRHHL
920 930 940 950 960 970
1328 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 16:22:30 2016 done: Mon Nov 7 16:22:31 2016
Total Scan time: 5.520 Total Display time: 0.260
Function used was FASTA [36.3.4 Apr, 2011]