Result of FASTA (omim) for
pFN21AE3447
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3447, 1281 aa
1>>>pF1KE3447 1281 - 1281 aa - 1281 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 13.7044+/-0.000641; mu= -17.4859+/- 0.039
mean_var=724.9212+/-157.235, 0's: 0 Z-trim(116.4): 851 B-trim: 0 in 0/57
Lambda= 0.047635
statistics sampled from 26523 (27541) to 26523 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.656), E-opt: 0.2 (0.323), width: 16
Scan time: 17.860
The best scores are: opt bits E(85289)
XP_005270666 (OMIM: 608003) PREDICTED: homeodomain (1281) 8448 598.1 1.2e-169
XP_005270667 (OMIM: 608003) PREDICTED: homeodomain (1280) 8429 596.8 3e-169
NP_938009 (OMIM: 608003) homeodomain-interacting p (1210) 7940 563.2 3.8e-159
XP_005270670 (OMIM: 608003) PREDICTED: homeodomain (1210) 7940 563.2 3.8e-159
XP_005270669 (OMIM: 608003) PREDICTED: homeodomain (1210) 7940 563.2 3.8e-159
XP_016856094 (OMIM: 608003) PREDICTED: homeodomain (1209) 7921 561.9 9.4e-159
XP_005270668 (OMIM: 608003) PREDICTED: homeodomain (1256) 7163 509.8 4.6e-143
NP_689909 (OMIM: 608003) homeodomain-interacting p (1075) 6873 489.8 4.2e-137
NP_938010 (OMIM: 608003) homeodomain-interacting p ( 836) 5505 395.7 7.1e-109
NP_852003 (OMIM: 608003) homeodomain-interacting p ( 816) 5317 382.7 5.4e-105
XP_011539279 (OMIM: 608003) PREDICTED: homeodomain (1241) 5058 365.2 1.6e-99
XP_006710506 (OMIM: 608003) PREDICTED: homeodomain (1247) 4261 310.4 5e-83
XP_016856095 (OMIM: 608003) PREDICTED: homeodomain ( 605) 3997 291.9 9e-78
XP_011514379 (OMIM: 606868) PREDICTED: homeodomain (1377) 3568 262.8 1.2e-68
XP_011514380 (OMIM: 606868) PREDICTED: homeodomain (1376) 3565 262.6 1.3e-68
XP_016867558 (OMIM: 606868) PREDICTED: homeodomain (1191) 3562 262.3 1.4e-68
XP_006715998 (OMIM: 606868) PREDICTED: homeodomain (1191) 3562 262.3 1.4e-68
NP_073577 (OMIM: 606868) homeodomain-interacting p (1198) 3562 262.3 1.4e-68
XP_011514383 (OMIM: 606868) PREDICTED: homeodomain (1206) 3562 262.3 1.4e-68
XP_011514382 (OMIM: 606868) PREDICTED: homeodomain (1349) 3135 233.0 1e-59
XP_011514381 (OMIM: 606868) PREDICTED: homeodomain (1350) 3129 232.6 1.4e-59
NP_001106710 (OMIM: 606868) homeodomain-interactin (1171) 3123 232.1 1.7e-59
NP_005725 (OMIM: 604424) homeodomain-interacting p (1215) 2944 219.9 8.6e-56
XP_016872565 (OMIM: 604424) PREDICTED: homeodomain (1215) 2944 219.9 8.6e-56
XP_005252786 (OMIM: 604424) PREDICTED: homeodomain (1215) 2944 219.9 8.6e-56
NP_001265091 (OMIM: 604424) homeodomain-interactin (1194) 2574 194.4 3.9e-48
XP_016872566 (OMIM: 604424) PREDICTED: homeodomain (1194) 2574 194.4 3.9e-48
NP_001265092 (OMIM: 604424) homeodomain-interactin (1194) 2574 194.4 3.9e-48
NP_001041665 (OMIM: 604424) homeodomain-interactin (1194) 2574 194.4 3.9e-48
NP_653286 (OMIM: 611712) homeodomain-interacting p ( 616) 1134 95.1 1.5e-18
XP_006723099 (OMIM: 611712) PREDICTED: homeodomain ( 619) 1134 95.1 1.5e-18
NP_569122 (OMIM: 600855,614104) dual specificity t ( 529) 765 69.7 6e-11
NP_567824 (OMIM: 600855,614104) dual specificity t ( 584) 765 69.8 6.4e-11
XP_011527787 (OMIM: 600855,614104) PREDICTED: dual ( 725) 765 69.9 7.4e-11
XP_016883775 (OMIM: 600855,614104) PREDICTED: dual ( 734) 765 69.9 7.5e-11
XP_006724042 (OMIM: 600855,614104) PREDICTED: dual ( 754) 765 69.9 7.6e-11
XP_016883774 (OMIM: 600855,614104) PREDICTED: dual ( 754) 765 69.9 7.6e-11
NP_569120 (OMIM: 600855,614104) dual specificity t ( 754) 765 69.9 7.6e-11
XP_016883773 (OMIM: 600855,614104) PREDICTED: dual ( 754) 765 69.9 7.6e-11
XP_011527786 (OMIM: 600855,614104) PREDICTED: dual ( 761) 765 69.9 7.6e-11
XP_006724039 (OMIM: 600855,614104) PREDICTED: dual ( 763) 765 69.9 7.6e-11
XP_006724041 (OMIM: 600855,614104) PREDICTED: dual ( 763) 765 69.9 7.6e-11
XP_006724040 (OMIM: 600855,614104) PREDICTED: dual ( 763) 765 69.9 7.6e-11
XP_011527785 (OMIM: 600855,614104) PREDICTED: dual ( 763) 765 69.9 7.6e-11
NP_001387 (OMIM: 600855,614104) dual specificity t ( 763) 765 69.9 7.6e-11
XP_011527784 (OMIM: 600855,614104) PREDICTED: dual ( 770) 765 69.9 7.7e-11
NP_004705 (OMIM: 604556,615812) dual specificity t ( 629) 752 68.9 1.3e-10
XP_005259455 (OMIM: 604556,615812) PREDICTED: dual ( 629) 752 68.9 1.3e-10
NP_006474 (OMIM: 604556,615812) dual specificity t ( 589) 714 66.3 7.3e-10
NP_006475 (OMIM: 604556,615812) dual specificity t ( 601) 714 66.3 7.4e-10
>>XP_005270666 (OMIM: 608003) PREDICTED: homeodomain-int (1281 aa)
initn: 8448 init1: 8448 opt: 8448 Z-score: 3166.6 bits: 598.1 E(85289): 1.2e-169
Smith-Waterman score: 8448; 100.0% identity (100.0% similar) in 1281 aa overlap (1-1281:1-1281)
10 20 30 40 50 60
pF1KE3 MTFYSWIPYHRQAPLNHRRVCSAEGAGSPGPALDPRWLPTEAHLLEAHRLLLQSVLCDRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MTFYSWIPYHRQAPLNHRRVCSAEGAGSPGPALDPRWLPTEAHLLEAHRLLLQSVLCDRP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 RESIQLHFRLSMASQLQVFSPPSVSSSAFCSAKKLKIEPSGWDVSGQSSNDKYYTHSKTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RESIQLHFRLSMASQLQVFSPPSVSSSAFCSAKKLKIEPSGWDVSGQSSNDKYYTHSKTL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 PATQGQANSSHQVANFNIPAYDQGLLLPAPAVEHIVVTAADSSGSAATSTFQSSQTLTHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PATQGQANSSHQVANFNIPAYDQGLLLPAPAVEHIVVTAADSSGSAATSTFQSSQTLTHR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 SNVSLLEPYQKCGLKRKSEEVDSNGSVQIIEEHPPLMLQNRTVVGAAATTTTVTTKSSSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SNVSLLEPYQKCGLKRKSEEVDSNGSVQIIEEHPPLMLQNRTVVGAAATTTTVTTKSSSS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 SGEGDYQLVQHEILCSMTNSYEVLEFLGRGTFGQVAKCWKRSTKEIVAIKILKNHPSYAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SGEGDYQLVQHEILCSMTNSYEVLEFLGRGTFGQVAKCWKRSTKEIVAIKILKNHPSYAR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 QGQIEVSILSRLSSENADEYNFVRSYECFQHKNHTCLVFEMLEQNLYDFLKQNKFSPLPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QGQIEVSILSRLSSENADEYNFVRSYECFQHKNHTCLVFEMLEQNLYDFLKQNKFSPLPL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 KYIRPILQQVATALMKLKSLGLIHADLKPENIMLVDPVRQPYRVKVIDFGSASHVSKAVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KYIRPILQQVATALMKLKSLGLIHADLKPENIMLVDPVRQPYRVKVIDFGSASHVSKAVC
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 STYLQSRYYRAPEIILGLPFCEAIDMWSLGCVIAELFLGWPLYPGASEYDQIRYISQTQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 STYLQSRYYRAPEIILGLPFCEAIDMWSLGCVIAELFLGWPLYPGASEYDQIRYISQTQG
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 LPAEYLLSAGTKTTRFFNRDPNLGYPLWRLKTPEEHELETGIKSKEARKYIFNCLDDMAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LPAEYLLSAGTKTTRFFNRDPNLGYPLWRLKTPEEHELETGIKSKEARKYIFNCLDDMAQ
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 VNMSTDLEGTDMLAEKADRREYIDLLKKMLTIDADKRITPLKTLNHQFVTMTHLLDFPHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VNMSTDLEGTDMLAEKADRREYIDLLKKMLTIDADKRITPLKTLNHQFVTMTHLLDFPHS
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 NHVKSCFQNMEICKRRVHMYDTVSQIKSPFTTHVAPNTSTNLTMSFSNQLNTVHNQASVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NHVKSCFQNMEICKRRVHMYDTVSQIKSPFTTHVAPNTSTNLTMSFSNQLNTVHNQASVL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 ASSSTAAAATLSLANSDVSLLNYQSALYPSSAAPVPGVAQQGVSLQPGTTQICTQTDPFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ASSSTAAAATLSLANSDVSLLNYQSALYPSSAAPVPGVAQQGVSLQPGTTQICTQTDPFQ
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 QTFIVCPPAFQTGLQATTKHSGFPVRMDNAVPIVPQAPAAQPLQIQSGVLTQGSCTPLMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QTFIVCPPAFQTGLQATTKHSGFPVRMDNAVPIVPQAPAAQPLQIQSGVLTQGSCTPLMV
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE3 ATLHPQVATITPQYAVPFTLSCAAGRPALVEQTAAVLQAWPGGTQQILLPSTWQQLPGVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ATLHPQVATITPQYAVPFTLSCAAGRPALVEQTAAVLQAWPGGTQQILLPSTWQQLPGVA
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE3 LHNSVQPTAMIPEAMGSGQQLADWRNAHSHGNQYSTIMQQPSLLTNHVTLATAQPLNVGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LHNSVQPTAMIPEAMGSGQQLADWRNAHSHGNQYSTIMQQPSLLTNHVTLATAQPLNVGV
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE3 AHVVRQQQSSSLPSKKNKQSAPVSSKSSLDVLPSQVYSLVGSSPLRTTSSYNSLVPVQDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AHVVRQQQSSSLPSKKNKQSAPVSSKSSLDVLPSQVYSLVGSSPLRTTSSYNSLVPVQDQ
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE3 HQPIIIPDTPSPPVSVITIRSDTDEEEDNKYKPSSSGLKPRSNVISYVTVNDSPDSDSSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HQPIIIPDTPSPPVSVITIRSDTDEEEDNKYKPSSSGLKPRSNVISYVTVNDSPDSDSSL
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE3 SSPYSTDTLSALRGNSGSVLEGPGRVVADGTGTRTIIVPPLKTQLGDCTVATQASGLLSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SSPYSTDTLSALRGNSGSVLEGPGRVVADGTGTRTIIVPPLKTQLGDCTVATQASGLLSN
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE3 KTKPVASVSGQSSGCCITPTGYRAQRGGTSAAQPLNLSQNQQSSAAPTSQERSSNPAPRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KTKPVASVSGQSSGCCITPTGYRAQRGGTSAAQPLNLSQNQQSSAAPTSQERSSNPAPRR
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE3 QQAFVAPLSQAPYTFQHGSPLHSTGHPHLAPAPAHLPSQAHLYTYAAPTSAAALGSTSSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QQAFVAPLSQAPYTFQHGSPLHSTGHPHLAPAPAHLPSQAHLYTYAAPTSAAALGSTSSI
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE3 AHLFSPQGSSRHAAAYTTHPSTLVHQVPVSVGPSLLTSASVAPAQYQHQFATQSYIGSSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AHLFSPQGSSRHAAAYTTHPSTLVHQVPVSVGPSLLTSASVAPAQYQHQFATQSYIGSSR
1210 1220 1230 1240 1250 1260
1270 1280
pF1KE3 GSTIYTGYPLSPTKISQYSYL
:::::::::::::::::::::
XP_005 GSTIYTGYPLSPTKISQYSYL
1270 1280
>>XP_005270667 (OMIM: 608003) PREDICTED: homeodomain-int (1280 aa)
initn: 5413 init1: 5413 opt: 8429 Z-score: 3159.5 bits: 596.8 E(85289): 3e-169
Smith-Waterman score: 8429; 99.9% identity (99.9% similar) in 1281 aa overlap (1-1281:1-1280)
10 20 30 40 50 60
pF1KE3 MTFYSWIPYHRQAPLNHRRVCSAEGAGSPGPALDPRWLPTEAHLLEAHRLLLQSVLCDRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MTFYSWIPYHRQAPLNHRRVCSAEGAGSPGPALDPRWLPTEAHLLEAHRLLLQSVLCDRP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 RESIQLHFRLSMASQLQVFSPPSVSSSAFCSAKKLKIEPSGWDVSGQSSNDKYYTHSKTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RESIQLHFRLSMASQLQVFSPPSVSSSAFCSAKKLKIEPSGWDVSGQSSNDKYYTHSKTL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 PATQGQANSSHQVANFNIPAYDQGLLLPAPAVEHIVVTAADSSGSAATSTFQSSQTLTHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PATQGQANSSHQVANFNIPAYDQGLLLPAPAVEHIVVTAADSSGSAATSTFQSSQTLTHR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 SNVSLLEPYQKCGLKRKSEEVDSNGSVQIIEEHPPLMLQNRTVVGAAATTTTVTTKSSSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SNVSLLEPYQKCGLKRKSEEVDSNGSVQIIEEHPPLMLQNRTVVGAAATTTTVTTKSSSS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 SGEGDYQLVQHEILCSMTNSYEVLEFLGRGTFGQVAKCWKRSTKEIVAIKILKNHPSYAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SGEGDYQLVQHEILCSMTNSYEVLEFLGRGTFGQVAKCWKRSTKEIVAIKILKNHPSYAR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 QGQIEVSILSRLSSENADEYNFVRSYECFQHKNHTCLVFEMLEQNLYDFLKQNKFSPLPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QGQIEVSILSRLSSENADEYNFVRSYECFQHKNHTCLVFEMLEQNLYDFLKQNKFSPLPL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 KYIRPILQQVATALMKLKSLGLIHADLKPENIMLVDPVRQPYRVKVIDFGSASHVSKAVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KYIRPILQQVATALMKLKSLGLIHADLKPENIMLVDPVRQPYRVKVIDFGSASHVSKAVC
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 STYLQSRYYRAPEIILGLPFCEAIDMWSLGCVIAELFLGWPLYPGASEYDQIRYISQTQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 STYLQSRYYRAPEIILGLPFCEAIDMWSLGCVIAELFLGWPLYPGASEYDQIRYISQTQG
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 LPAEYLLSAGTKTTRFFNRDPNLGYPLWRLKTPEEHELETGIKSKEARKYIFNCLDDMAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LPAEYLLSAGTKTTRFFNRDPNLGYPLWRLKTPEEHELETGIKSKEARKYIFNCLDDMAQ
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 VNMSTDLEGTDMLAEKADRREYIDLLKKMLTIDADKRITPLKTLNHQFVTMTHLLDFPHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VNMSTDLEGTDMLAEKADRREYIDLLKKMLTIDADKRITPLKTLNHQFVTMTHLLDFPHS
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 NHVKSCFQNMEICKRRVHMYDTVSQIKSPFTTHVAPNTSTNLTMSFSNQLNTVHNQASVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NHVKSCFQNMEICKRRVHMYDTVSQIKSPFTTHVAPNTSTNLTMSFSNQLNTVHNQASVL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 ASSSTAAAATLSLANSDVSLLNYQSALYPSSAAPVPGVAQQGVSLQPGTTQICTQTDPFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ASSSTAAAATLSLANSDVSLLNYQSALYPSSAAPVPGVAQQGVSLQPGTTQICTQTDPFQ
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 QTFIVCPPAFQTGLQATTKHSGFPVRMDNAVPIVPQAPAAQPLQIQSGVLTQGSCTPLMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QTFIVCPPAFQTGLQATTKHSGFPVRMDNAVPIVPQAPAAQPLQIQSGVLTQGSCTPLMV
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE3 ATLHPQVATITPQYAVPFTLSCAAGRPALVEQTAAVLQAWPGGTQQILLPSTWQQLPGVA
::::::::::::::::::::::::::::::::::::: ::::::::::::::::::::::
XP_005 ATLHPQVATITPQYAVPFTLSCAAGRPALVEQTAAVL-AWPGGTQQILLPSTWQQLPGVA
790 800 810 820 830
850 860 870 880 890 900
pF1KE3 LHNSVQPTAMIPEAMGSGQQLADWRNAHSHGNQYSTIMQQPSLLTNHVTLATAQPLNVGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LHNSVQPTAMIPEAMGSGQQLADWRNAHSHGNQYSTIMQQPSLLTNHVTLATAQPLNVGV
840 850 860 870 880 890
910 920 930 940 950 960
pF1KE3 AHVVRQQQSSSLPSKKNKQSAPVSSKSSLDVLPSQVYSLVGSSPLRTTSSYNSLVPVQDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AHVVRQQQSSSLPSKKNKQSAPVSSKSSLDVLPSQVYSLVGSSPLRTTSSYNSLVPVQDQ
900 910 920 930 940 950
970 980 990 1000 1010 1020
pF1KE3 HQPIIIPDTPSPPVSVITIRSDTDEEEDNKYKPSSSGLKPRSNVISYVTVNDSPDSDSSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HQPIIIPDTPSPPVSVITIRSDTDEEEDNKYKPSSSGLKPRSNVISYVTVNDSPDSDSSL
960 970 980 990 1000 1010
1030 1040 1050 1060 1070 1080
pF1KE3 SSPYSTDTLSALRGNSGSVLEGPGRVVADGTGTRTIIVPPLKTQLGDCTVATQASGLLSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SSPYSTDTLSALRGNSGSVLEGPGRVVADGTGTRTIIVPPLKTQLGDCTVATQASGLLSN
1020 1030 1040 1050 1060 1070
1090 1100 1110 1120 1130 1140
pF1KE3 KTKPVASVSGQSSGCCITPTGYRAQRGGTSAAQPLNLSQNQQSSAAPTSQERSSNPAPRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KTKPVASVSGQSSGCCITPTGYRAQRGGTSAAQPLNLSQNQQSSAAPTSQERSSNPAPRR
1080 1090 1100 1110 1120 1130
1150 1160 1170 1180 1190 1200
pF1KE3 QQAFVAPLSQAPYTFQHGSPLHSTGHPHLAPAPAHLPSQAHLYTYAAPTSAAALGSTSSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QQAFVAPLSQAPYTFQHGSPLHSTGHPHLAPAPAHLPSQAHLYTYAAPTSAAALGSTSSI
1140 1150 1160 1170 1180 1190
1210 1220 1230 1240 1250 1260
pF1KE3 AHLFSPQGSSRHAAAYTTHPSTLVHQVPVSVGPSLLTSASVAPAQYQHQFATQSYIGSSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AHLFSPQGSSRHAAAYTTHPSTLVHQVPVSVGPSLLTSASVAPAQYQHQFATQSYIGSSR
1200 1210 1220 1230 1240 1250
1270 1280
pF1KE3 GSTIYTGYPLSPTKISQYSYL
:::::::::::::::::::::
XP_005 GSTIYTGYPLSPTKISQYSYL
1260 1270 1280
>>NP_938009 (OMIM: 608003) homeodomain-interacting prote (1210 aa)
initn: 7940 init1: 7940 opt: 7940 Z-score: 2978.2 bits: 563.2 E(85289): 3.8e-159
Smith-Waterman score: 7940; 100.0% identity (100.0% similar) in 1210 aa overlap (72-1281:1-1210)
50 60 70 80 90 100
pF1KE3 AHLLEAHRLLLQSVLCDRPRESIQLHFRLSMASQLQVFSPPSVSSSAFCSAKKLKIEPSG
::::::::::::::::::::::::::::::
NP_938 MASQLQVFSPPSVSSSAFCSAKKLKIEPSG
10 20 30
110 120 130 140 150 160
pF1KE3 WDVSGQSSNDKYYTHSKTLPATQGQANSSHQVANFNIPAYDQGLLLPAPAVEHIVVTAAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 WDVSGQSSNDKYYTHSKTLPATQGQANSSHQVANFNIPAYDQGLLLPAPAVEHIVVTAAD
40 50 60 70 80 90
170 180 190 200 210 220
pF1KE3 SSGSAATSTFQSSQTLTHRSNVSLLEPYQKCGLKRKSEEVDSNGSVQIIEEHPPLMLQNR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 SSGSAATSTFQSSQTLTHRSNVSLLEPYQKCGLKRKSEEVDSNGSVQIIEEHPPLMLQNR
100 110 120 130 140 150
230 240 250 260 270 280
pF1KE3 TVVGAAATTTTVTTKSSSSSGEGDYQLVQHEILCSMTNSYEVLEFLGRGTFGQVAKCWKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 TVVGAAATTTTVTTKSSSSSGEGDYQLVQHEILCSMTNSYEVLEFLGRGTFGQVAKCWKR
160 170 180 190 200 210
290 300 310 320 330 340
pF1KE3 STKEIVAIKILKNHPSYARQGQIEVSILSRLSSENADEYNFVRSYECFQHKNHTCLVFEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 STKEIVAIKILKNHPSYARQGQIEVSILSRLSSENADEYNFVRSYECFQHKNHTCLVFEM
220 230 240 250 260 270
350 360 370 380 390 400
pF1KE3 LEQNLYDFLKQNKFSPLPLKYIRPILQQVATALMKLKSLGLIHADLKPENIMLVDPVRQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 LEQNLYDFLKQNKFSPLPLKYIRPILQQVATALMKLKSLGLIHADLKPENIMLVDPVRQP
280 290 300 310 320 330
410 420 430 440 450 460
pF1KE3 YRVKVIDFGSASHVSKAVCSTYLQSRYYRAPEIILGLPFCEAIDMWSLGCVIAELFLGWP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 YRVKVIDFGSASHVSKAVCSTYLQSRYYRAPEIILGLPFCEAIDMWSLGCVIAELFLGWP
340 350 360 370 380 390
470 480 490 500 510 520
pF1KE3 LYPGASEYDQIRYISQTQGLPAEYLLSAGTKTTRFFNRDPNLGYPLWRLKTPEEHELETG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 LYPGASEYDQIRYISQTQGLPAEYLLSAGTKTTRFFNRDPNLGYPLWRLKTPEEHELETG
400 410 420 430 440 450
530 540 550 560 570 580
pF1KE3 IKSKEARKYIFNCLDDMAQVNMSTDLEGTDMLAEKADRREYIDLLKKMLTIDADKRITPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 IKSKEARKYIFNCLDDMAQVNMSTDLEGTDMLAEKADRREYIDLLKKMLTIDADKRITPL
460 470 480 490 500 510
590 600 610 620 630 640
pF1KE3 KTLNHQFVTMTHLLDFPHSNHVKSCFQNMEICKRRVHMYDTVSQIKSPFTTHVAPNTSTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 KTLNHQFVTMTHLLDFPHSNHVKSCFQNMEICKRRVHMYDTVSQIKSPFTTHVAPNTSTN
520 530 540 550 560 570
650 660 670 680 690 700
pF1KE3 LTMSFSNQLNTVHNQASVLASSSTAAAATLSLANSDVSLLNYQSALYPSSAAPVPGVAQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 LTMSFSNQLNTVHNQASVLASSSTAAAATLSLANSDVSLLNYQSALYPSSAAPVPGVAQQ
580 590 600 610 620 630
710 720 730 740 750 760
pF1KE3 GVSLQPGTTQICTQTDPFQQTFIVCPPAFQTGLQATTKHSGFPVRMDNAVPIVPQAPAAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 GVSLQPGTTQICTQTDPFQQTFIVCPPAFQTGLQATTKHSGFPVRMDNAVPIVPQAPAAQ
640 650 660 670 680 690
770 780 790 800 810 820
pF1KE3 PLQIQSGVLTQGSCTPLMVATLHPQVATITPQYAVPFTLSCAAGRPALVEQTAAVLQAWP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 PLQIQSGVLTQGSCTPLMVATLHPQVATITPQYAVPFTLSCAAGRPALVEQTAAVLQAWP
700 710 720 730 740 750
830 840 850 860 870 880
pF1KE3 GGTQQILLPSTWQQLPGVALHNSVQPTAMIPEAMGSGQQLADWRNAHSHGNQYSTIMQQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 GGTQQILLPSTWQQLPGVALHNSVQPTAMIPEAMGSGQQLADWRNAHSHGNQYSTIMQQP
760 770 780 790 800 810
890 900 910 920 930 940
pF1KE3 SLLTNHVTLATAQPLNVGVAHVVRQQQSSSLPSKKNKQSAPVSSKSSLDVLPSQVYSLVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 SLLTNHVTLATAQPLNVGVAHVVRQQQSSSLPSKKNKQSAPVSSKSSLDVLPSQVYSLVG
820 830 840 850 860 870
950 960 970 980 990 1000
pF1KE3 SSPLRTTSSYNSLVPVQDQHQPIIIPDTPSPPVSVITIRSDTDEEEDNKYKPSSSGLKPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 SSPLRTTSSYNSLVPVQDQHQPIIIPDTPSPPVSVITIRSDTDEEEDNKYKPSSSGLKPR
880 890 900 910 920 930
1010 1020 1030 1040 1050 1060
pF1KE3 SNVISYVTVNDSPDSDSSLSSPYSTDTLSALRGNSGSVLEGPGRVVADGTGTRTIIVPPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 SNVISYVTVNDSPDSDSSLSSPYSTDTLSALRGNSGSVLEGPGRVVADGTGTRTIIVPPL
940 950 960 970 980 990
1070 1080 1090 1100 1110 1120
pF1KE3 KTQLGDCTVATQASGLLSNKTKPVASVSGQSSGCCITPTGYRAQRGGTSAAQPLNLSQNQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 KTQLGDCTVATQASGLLSNKTKPVASVSGQSSGCCITPTGYRAQRGGTSAAQPLNLSQNQ
1000 1010 1020 1030 1040 1050
1130 1140 1150 1160 1170 1180
pF1KE3 QSSAAPTSQERSSNPAPRRQQAFVAPLSQAPYTFQHGSPLHSTGHPHLAPAPAHLPSQAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 QSSAAPTSQERSSNPAPRRQQAFVAPLSQAPYTFQHGSPLHSTGHPHLAPAPAHLPSQAH
1060 1070 1080 1090 1100 1110
1190 1200 1210 1220 1230 1240
pF1KE3 LYTYAAPTSAAALGSTSSIAHLFSPQGSSRHAAAYTTHPSTLVHQVPVSVGPSLLTSASV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 LYTYAAPTSAAALGSTSSIAHLFSPQGSSRHAAAYTTHPSTLVHQVPVSVGPSLLTSASV
1120 1130 1140 1150 1160 1170
1250 1260 1270 1280
pF1KE3 APAQYQHQFATQSYIGSSRGSTIYTGYPLSPTKISQYSYL
::::::::::::::::::::::::::::::::::::::::
NP_938 APAQYQHQFATQSYIGSSRGSTIYTGYPLSPTKISQYSYL
1180 1190 1200 1210
>>XP_005270670 (OMIM: 608003) PREDICTED: homeodomain-int (1210 aa)
initn: 7940 init1: 7940 opt: 7940 Z-score: 2978.2 bits: 563.2 E(85289): 3.8e-159
Smith-Waterman score: 7940; 100.0% identity (100.0% similar) in 1210 aa overlap (72-1281:1-1210)
50 60 70 80 90 100
pF1KE3 AHLLEAHRLLLQSVLCDRPRESIQLHFRLSMASQLQVFSPPSVSSSAFCSAKKLKIEPSG
::::::::::::::::::::::::::::::
XP_005 MASQLQVFSPPSVSSSAFCSAKKLKIEPSG
10 20 30
110 120 130 140 150 160
pF1KE3 WDVSGQSSNDKYYTHSKTLPATQGQANSSHQVANFNIPAYDQGLLLPAPAVEHIVVTAAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 WDVSGQSSNDKYYTHSKTLPATQGQANSSHQVANFNIPAYDQGLLLPAPAVEHIVVTAAD
40 50 60 70 80 90
170 180 190 200 210 220
pF1KE3 SSGSAATSTFQSSQTLTHRSNVSLLEPYQKCGLKRKSEEVDSNGSVQIIEEHPPLMLQNR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SSGSAATSTFQSSQTLTHRSNVSLLEPYQKCGLKRKSEEVDSNGSVQIIEEHPPLMLQNR
100 110 120 130 140 150
230 240 250 260 270 280
pF1KE3 TVVGAAATTTTVTTKSSSSSGEGDYQLVQHEILCSMTNSYEVLEFLGRGTFGQVAKCWKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TVVGAAATTTTVTTKSSSSSGEGDYQLVQHEILCSMTNSYEVLEFLGRGTFGQVAKCWKR
160 170 180 190 200 210
290 300 310 320 330 340
pF1KE3 STKEIVAIKILKNHPSYARQGQIEVSILSRLSSENADEYNFVRSYECFQHKNHTCLVFEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 STKEIVAIKILKNHPSYARQGQIEVSILSRLSSENADEYNFVRSYECFQHKNHTCLVFEM
220 230 240 250 260 270
350 360 370 380 390 400
pF1KE3 LEQNLYDFLKQNKFSPLPLKYIRPILQQVATALMKLKSLGLIHADLKPENIMLVDPVRQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LEQNLYDFLKQNKFSPLPLKYIRPILQQVATALMKLKSLGLIHADLKPENIMLVDPVRQP
280 290 300 310 320 330
410 420 430 440 450 460
pF1KE3 YRVKVIDFGSASHVSKAVCSTYLQSRYYRAPEIILGLPFCEAIDMWSLGCVIAELFLGWP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YRVKVIDFGSASHVSKAVCSTYLQSRYYRAPEIILGLPFCEAIDMWSLGCVIAELFLGWP
340 350 360 370 380 390
470 480 490 500 510 520
pF1KE3 LYPGASEYDQIRYISQTQGLPAEYLLSAGTKTTRFFNRDPNLGYPLWRLKTPEEHELETG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LYPGASEYDQIRYISQTQGLPAEYLLSAGTKTTRFFNRDPNLGYPLWRLKTPEEHELETG
400 410 420 430 440 450
530 540 550 560 570 580
pF1KE3 IKSKEARKYIFNCLDDMAQVNMSTDLEGTDMLAEKADRREYIDLLKKMLTIDADKRITPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IKSKEARKYIFNCLDDMAQVNMSTDLEGTDMLAEKADRREYIDLLKKMLTIDADKRITPL
460 470 480 490 500 510
590 600 610 620 630 640
pF1KE3 KTLNHQFVTMTHLLDFPHSNHVKSCFQNMEICKRRVHMYDTVSQIKSPFTTHVAPNTSTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KTLNHQFVTMTHLLDFPHSNHVKSCFQNMEICKRRVHMYDTVSQIKSPFTTHVAPNTSTN
520 530 540 550 560 570
650 660 670 680 690 700
pF1KE3 LTMSFSNQLNTVHNQASVLASSSTAAAATLSLANSDVSLLNYQSALYPSSAAPVPGVAQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LTMSFSNQLNTVHNQASVLASSSTAAAATLSLANSDVSLLNYQSALYPSSAAPVPGVAQQ
580 590 600 610 620 630
710 720 730 740 750 760
pF1KE3 GVSLQPGTTQICTQTDPFQQTFIVCPPAFQTGLQATTKHSGFPVRMDNAVPIVPQAPAAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GVSLQPGTTQICTQTDPFQQTFIVCPPAFQTGLQATTKHSGFPVRMDNAVPIVPQAPAAQ
640 650 660 670 680 690
770 780 790 800 810 820
pF1KE3 PLQIQSGVLTQGSCTPLMVATLHPQVATITPQYAVPFTLSCAAGRPALVEQTAAVLQAWP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PLQIQSGVLTQGSCTPLMVATLHPQVATITPQYAVPFTLSCAAGRPALVEQTAAVLQAWP
700 710 720 730 740 750
830 840 850 860 870 880
pF1KE3 GGTQQILLPSTWQQLPGVALHNSVQPTAMIPEAMGSGQQLADWRNAHSHGNQYSTIMQQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GGTQQILLPSTWQQLPGVALHNSVQPTAMIPEAMGSGQQLADWRNAHSHGNQYSTIMQQP
760 770 780 790 800 810
890 900 910 920 930 940
pF1KE3 SLLTNHVTLATAQPLNVGVAHVVRQQQSSSLPSKKNKQSAPVSSKSSLDVLPSQVYSLVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SLLTNHVTLATAQPLNVGVAHVVRQQQSSSLPSKKNKQSAPVSSKSSLDVLPSQVYSLVG
820 830 840 850 860 870
950 960 970 980 990 1000
pF1KE3 SSPLRTTSSYNSLVPVQDQHQPIIIPDTPSPPVSVITIRSDTDEEEDNKYKPSSSGLKPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SSPLRTTSSYNSLVPVQDQHQPIIIPDTPSPPVSVITIRSDTDEEEDNKYKPSSSGLKPR
880 890 900 910 920 930
1010 1020 1030 1040 1050 1060
pF1KE3 SNVISYVTVNDSPDSDSSLSSPYSTDTLSALRGNSGSVLEGPGRVVADGTGTRTIIVPPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SNVISYVTVNDSPDSDSSLSSPYSTDTLSALRGNSGSVLEGPGRVVADGTGTRTIIVPPL
940 950 960 970 980 990
1070 1080 1090 1100 1110 1120
pF1KE3 KTQLGDCTVATQASGLLSNKTKPVASVSGQSSGCCITPTGYRAQRGGTSAAQPLNLSQNQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KTQLGDCTVATQASGLLSNKTKPVASVSGQSSGCCITPTGYRAQRGGTSAAQPLNLSQNQ
1000 1010 1020 1030 1040 1050
1130 1140 1150 1160 1170 1180
pF1KE3 QSSAAPTSQERSSNPAPRRQQAFVAPLSQAPYTFQHGSPLHSTGHPHLAPAPAHLPSQAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QSSAAPTSQERSSNPAPRRQQAFVAPLSQAPYTFQHGSPLHSTGHPHLAPAPAHLPSQAH
1060 1070 1080 1090 1100 1110
1190 1200 1210 1220 1230 1240
pF1KE3 LYTYAAPTSAAALGSTSSIAHLFSPQGSSRHAAAYTTHPSTLVHQVPVSVGPSLLTSASV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LYTYAAPTSAAALGSTSSIAHLFSPQGSSRHAAAYTTHPSTLVHQVPVSVGPSLLTSASV
1120 1130 1140 1150 1160 1170
1250 1260 1270 1280
pF1KE3 APAQYQHQFATQSYIGSSRGSTIYTGYPLSPTKISQYSYL
::::::::::::::::::::::::::::::::::::::::
XP_005 APAQYQHQFATQSYIGSSRGSTIYTGYPLSPTKISQYSYL
1180 1190 1200 1210
>>XP_005270669 (OMIM: 608003) PREDICTED: homeodomain-int (1210 aa)
initn: 7940 init1: 7940 opt: 7940 Z-score: 2978.2 bits: 563.2 E(85289): 3.8e-159
Smith-Waterman score: 7940; 100.0% identity (100.0% similar) in 1210 aa overlap (72-1281:1-1210)
50 60 70 80 90 100
pF1KE3 AHLLEAHRLLLQSVLCDRPRESIQLHFRLSMASQLQVFSPPSVSSSAFCSAKKLKIEPSG
::::::::::::::::::::::::::::::
XP_005 MASQLQVFSPPSVSSSAFCSAKKLKIEPSG
10 20 30
110 120 130 140 150 160
pF1KE3 WDVSGQSSNDKYYTHSKTLPATQGQANSSHQVANFNIPAYDQGLLLPAPAVEHIVVTAAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 WDVSGQSSNDKYYTHSKTLPATQGQANSSHQVANFNIPAYDQGLLLPAPAVEHIVVTAAD
40 50 60 70 80 90
170 180 190 200 210 220
pF1KE3 SSGSAATSTFQSSQTLTHRSNVSLLEPYQKCGLKRKSEEVDSNGSVQIIEEHPPLMLQNR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SSGSAATSTFQSSQTLTHRSNVSLLEPYQKCGLKRKSEEVDSNGSVQIIEEHPPLMLQNR
100 110 120 130 140 150
230 240 250 260 270 280
pF1KE3 TVVGAAATTTTVTTKSSSSSGEGDYQLVQHEILCSMTNSYEVLEFLGRGTFGQVAKCWKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TVVGAAATTTTVTTKSSSSSGEGDYQLVQHEILCSMTNSYEVLEFLGRGTFGQVAKCWKR
160 170 180 190 200 210
290 300 310 320 330 340
pF1KE3 STKEIVAIKILKNHPSYARQGQIEVSILSRLSSENADEYNFVRSYECFQHKNHTCLVFEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 STKEIVAIKILKNHPSYARQGQIEVSILSRLSSENADEYNFVRSYECFQHKNHTCLVFEM
220 230 240 250 260 270
350 360 370 380 390 400
pF1KE3 LEQNLYDFLKQNKFSPLPLKYIRPILQQVATALMKLKSLGLIHADLKPENIMLVDPVRQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LEQNLYDFLKQNKFSPLPLKYIRPILQQVATALMKLKSLGLIHADLKPENIMLVDPVRQP
280 290 300 310 320 330
410 420 430 440 450 460
pF1KE3 YRVKVIDFGSASHVSKAVCSTYLQSRYYRAPEIILGLPFCEAIDMWSLGCVIAELFLGWP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YRVKVIDFGSASHVSKAVCSTYLQSRYYRAPEIILGLPFCEAIDMWSLGCVIAELFLGWP
340 350 360 370 380 390
470 480 490 500 510 520
pF1KE3 LYPGASEYDQIRYISQTQGLPAEYLLSAGTKTTRFFNRDPNLGYPLWRLKTPEEHELETG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LYPGASEYDQIRYISQTQGLPAEYLLSAGTKTTRFFNRDPNLGYPLWRLKTPEEHELETG
400 410 420 430 440 450
530 540 550 560 570 580
pF1KE3 IKSKEARKYIFNCLDDMAQVNMSTDLEGTDMLAEKADRREYIDLLKKMLTIDADKRITPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IKSKEARKYIFNCLDDMAQVNMSTDLEGTDMLAEKADRREYIDLLKKMLTIDADKRITPL
460 470 480 490 500 510
590 600 610 620 630 640
pF1KE3 KTLNHQFVTMTHLLDFPHSNHVKSCFQNMEICKRRVHMYDTVSQIKSPFTTHVAPNTSTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KTLNHQFVTMTHLLDFPHSNHVKSCFQNMEICKRRVHMYDTVSQIKSPFTTHVAPNTSTN
520 530 540 550 560 570
650 660 670 680 690 700
pF1KE3 LTMSFSNQLNTVHNQASVLASSSTAAAATLSLANSDVSLLNYQSALYPSSAAPVPGVAQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LTMSFSNQLNTVHNQASVLASSSTAAAATLSLANSDVSLLNYQSALYPSSAAPVPGVAQQ
580 590 600 610 620 630
710 720 730 740 750 760
pF1KE3 GVSLQPGTTQICTQTDPFQQTFIVCPPAFQTGLQATTKHSGFPVRMDNAVPIVPQAPAAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GVSLQPGTTQICTQTDPFQQTFIVCPPAFQTGLQATTKHSGFPVRMDNAVPIVPQAPAAQ
640 650 660 670 680 690
770 780 790 800 810 820
pF1KE3 PLQIQSGVLTQGSCTPLMVATLHPQVATITPQYAVPFTLSCAAGRPALVEQTAAVLQAWP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PLQIQSGVLTQGSCTPLMVATLHPQVATITPQYAVPFTLSCAAGRPALVEQTAAVLQAWP
700 710 720 730 740 750
830 840 850 860 870 880
pF1KE3 GGTQQILLPSTWQQLPGVALHNSVQPTAMIPEAMGSGQQLADWRNAHSHGNQYSTIMQQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GGTQQILLPSTWQQLPGVALHNSVQPTAMIPEAMGSGQQLADWRNAHSHGNQYSTIMQQP
760 770 780 790 800 810
890 900 910 920 930 940
pF1KE3 SLLTNHVTLATAQPLNVGVAHVVRQQQSSSLPSKKNKQSAPVSSKSSLDVLPSQVYSLVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SLLTNHVTLATAQPLNVGVAHVVRQQQSSSLPSKKNKQSAPVSSKSSLDVLPSQVYSLVG
820 830 840 850 860 870
950 960 970 980 990 1000
pF1KE3 SSPLRTTSSYNSLVPVQDQHQPIIIPDTPSPPVSVITIRSDTDEEEDNKYKPSSSGLKPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SSPLRTTSSYNSLVPVQDQHQPIIIPDTPSPPVSVITIRSDTDEEEDNKYKPSSSGLKPR
880 890 900 910 920 930
1010 1020 1030 1040 1050 1060
pF1KE3 SNVISYVTVNDSPDSDSSLSSPYSTDTLSALRGNSGSVLEGPGRVVADGTGTRTIIVPPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SNVISYVTVNDSPDSDSSLSSPYSTDTLSALRGNSGSVLEGPGRVVADGTGTRTIIVPPL
940 950 960 970 980 990
1070 1080 1090 1100 1110 1120
pF1KE3 KTQLGDCTVATQASGLLSNKTKPVASVSGQSSGCCITPTGYRAQRGGTSAAQPLNLSQNQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KTQLGDCTVATQASGLLSNKTKPVASVSGQSSGCCITPTGYRAQRGGTSAAQPLNLSQNQ
1000 1010 1020 1030 1040 1050
1130 1140 1150 1160 1170 1180
pF1KE3 QSSAAPTSQERSSNPAPRRQQAFVAPLSQAPYTFQHGSPLHSTGHPHLAPAPAHLPSQAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QSSAAPTSQERSSNPAPRRQQAFVAPLSQAPYTFQHGSPLHSTGHPHLAPAPAHLPSQAH
1060 1070 1080 1090 1100 1110
1190 1200 1210 1220 1230 1240
pF1KE3 LYTYAAPTSAAALGSTSSIAHLFSPQGSSRHAAAYTTHPSTLVHQVPVSVGPSLLTSASV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LYTYAAPTSAAALGSTSSIAHLFSPQGSSRHAAAYTTHPSTLVHQVPVSVGPSLLTSASV
1120 1130 1140 1150 1160 1170
1250 1260 1270 1280
pF1KE3 APAQYQHQFATQSYIGSSRGSTIYTGYPLSPTKISQYSYL
::::::::::::::::::::::::::::::::::::::::
XP_005 APAQYQHQFATQSYIGSSRGSTIYTGYPLSPTKISQYSYL
1180 1190 1200 1210
>>XP_016856094 (OMIM: 608003) PREDICTED: homeodomain-int (1209 aa)
initn: 4905 init1: 4905 opt: 7921 Z-score: 2971.1 bits: 561.9 E(85289): 9.4e-159
Smith-Waterman score: 7921; 99.9% identity (99.9% similar) in 1210 aa overlap (72-1281:1-1209)
50 60 70 80 90 100
pF1KE3 AHLLEAHRLLLQSVLCDRPRESIQLHFRLSMASQLQVFSPPSVSSSAFCSAKKLKIEPSG
::::::::::::::::::::::::::::::
XP_016 MASQLQVFSPPSVSSSAFCSAKKLKIEPSG
10 20 30
110 120 130 140 150 160
pF1KE3 WDVSGQSSNDKYYTHSKTLPATQGQANSSHQVANFNIPAYDQGLLLPAPAVEHIVVTAAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WDVSGQSSNDKYYTHSKTLPATQGQANSSHQVANFNIPAYDQGLLLPAPAVEHIVVTAAD
40 50 60 70 80 90
170 180 190 200 210 220
pF1KE3 SSGSAATSTFQSSQTLTHRSNVSLLEPYQKCGLKRKSEEVDSNGSVQIIEEHPPLMLQNR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSGSAATSTFQSSQTLTHRSNVSLLEPYQKCGLKRKSEEVDSNGSVQIIEEHPPLMLQNR
100 110 120 130 140 150
230 240 250 260 270 280
pF1KE3 TVVGAAATTTTVTTKSSSSSGEGDYQLVQHEILCSMTNSYEVLEFLGRGTFGQVAKCWKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TVVGAAATTTTVTTKSSSSSGEGDYQLVQHEILCSMTNSYEVLEFLGRGTFGQVAKCWKR
160 170 180 190 200 210
290 300 310 320 330 340
pF1KE3 STKEIVAIKILKNHPSYARQGQIEVSILSRLSSENADEYNFVRSYECFQHKNHTCLVFEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 STKEIVAIKILKNHPSYARQGQIEVSILSRLSSENADEYNFVRSYECFQHKNHTCLVFEM
220 230 240 250 260 270
350 360 370 380 390 400
pF1KE3 LEQNLYDFLKQNKFSPLPLKYIRPILQQVATALMKLKSLGLIHADLKPENIMLVDPVRQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LEQNLYDFLKQNKFSPLPLKYIRPILQQVATALMKLKSLGLIHADLKPENIMLVDPVRQP
280 290 300 310 320 330
410 420 430 440 450 460
pF1KE3 YRVKVIDFGSASHVSKAVCSTYLQSRYYRAPEIILGLPFCEAIDMWSLGCVIAELFLGWP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YRVKVIDFGSASHVSKAVCSTYLQSRYYRAPEIILGLPFCEAIDMWSLGCVIAELFLGWP
340 350 360 370 380 390
470 480 490 500 510 520
pF1KE3 LYPGASEYDQIRYISQTQGLPAEYLLSAGTKTTRFFNRDPNLGYPLWRLKTPEEHELETG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LYPGASEYDQIRYISQTQGLPAEYLLSAGTKTTRFFNRDPNLGYPLWRLKTPEEHELETG
400 410 420 430 440 450
530 540 550 560 570 580
pF1KE3 IKSKEARKYIFNCLDDMAQVNMSTDLEGTDMLAEKADRREYIDLLKKMLTIDADKRITPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IKSKEARKYIFNCLDDMAQVNMSTDLEGTDMLAEKADRREYIDLLKKMLTIDADKRITPL
460 470 480 490 500 510
590 600 610 620 630 640
pF1KE3 KTLNHQFVTMTHLLDFPHSNHVKSCFQNMEICKRRVHMYDTVSQIKSPFTTHVAPNTSTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KTLNHQFVTMTHLLDFPHSNHVKSCFQNMEICKRRVHMYDTVSQIKSPFTTHVAPNTSTN
520 530 540 550 560 570
650 660 670 680 690 700
pF1KE3 LTMSFSNQLNTVHNQASVLASSSTAAAATLSLANSDVSLLNYQSALYPSSAAPVPGVAQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTMSFSNQLNTVHNQASVLASSSTAAAATLSLANSDVSLLNYQSALYPSSAAPVPGVAQQ
580 590 600 610 620 630
710 720 730 740 750 760
pF1KE3 GVSLQPGTTQICTQTDPFQQTFIVCPPAFQTGLQATTKHSGFPVRMDNAVPIVPQAPAAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GVSLQPGTTQICTQTDPFQQTFIVCPPAFQTGLQATTKHSGFPVRMDNAVPIVPQAPAAQ
640 650 660 670 680 690
770 780 790 800 810 820
pF1KE3 PLQIQSGVLTQGSCTPLMVATLHPQVATITPQYAVPFTLSCAAGRPALVEQTAAVLQAWP
:::::::::::::::::::::::::::::::::::::::::::::::::::::::: :::
XP_016 PLQIQSGVLTQGSCTPLMVATLHPQVATITPQYAVPFTLSCAAGRPALVEQTAAVL-AWP
700 710 720 730 740
830 840 850 860 870 880
pF1KE3 GGTQQILLPSTWQQLPGVALHNSVQPTAMIPEAMGSGQQLADWRNAHSHGNQYSTIMQQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GGTQQILLPSTWQQLPGVALHNSVQPTAMIPEAMGSGQQLADWRNAHSHGNQYSTIMQQP
750 760 770 780 790 800
890 900 910 920 930 940
pF1KE3 SLLTNHVTLATAQPLNVGVAHVVRQQQSSSLPSKKNKQSAPVSSKSSLDVLPSQVYSLVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLLTNHVTLATAQPLNVGVAHVVRQQQSSSLPSKKNKQSAPVSSKSSLDVLPSQVYSLVG
810 820 830 840 850 860
950 960 970 980 990 1000
pF1KE3 SSPLRTTSSYNSLVPVQDQHQPIIIPDTPSPPVSVITIRSDTDEEEDNKYKPSSSGLKPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSPLRTTSSYNSLVPVQDQHQPIIIPDTPSPPVSVITIRSDTDEEEDNKYKPSSSGLKPR
870 880 890 900 910 920
1010 1020 1030 1040 1050 1060
pF1KE3 SNVISYVTVNDSPDSDSSLSSPYSTDTLSALRGNSGSVLEGPGRVVADGTGTRTIIVPPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SNVISYVTVNDSPDSDSSLSSPYSTDTLSALRGNSGSVLEGPGRVVADGTGTRTIIVPPL
930 940 950 960 970 980
1070 1080 1090 1100 1110 1120
pF1KE3 KTQLGDCTVATQASGLLSNKTKPVASVSGQSSGCCITPTGYRAQRGGTSAAQPLNLSQNQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KTQLGDCTVATQASGLLSNKTKPVASVSGQSSGCCITPTGYRAQRGGTSAAQPLNLSQNQ
990 1000 1010 1020 1030 1040
1130 1140 1150 1160 1170 1180
pF1KE3 QSSAAPTSQERSSNPAPRRQQAFVAPLSQAPYTFQHGSPLHSTGHPHLAPAPAHLPSQAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QSSAAPTSQERSSNPAPRRQQAFVAPLSQAPYTFQHGSPLHSTGHPHLAPAPAHLPSQAH
1050 1060 1070 1080 1090 1100
1190 1200 1210 1220 1230 1240
pF1KE3 LYTYAAPTSAAALGSTSSIAHLFSPQGSSRHAAAYTTHPSTLVHQVPVSVGPSLLTSASV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LYTYAAPTSAAALGSTSSIAHLFSPQGSSRHAAAYTTHPSTLVHQVPVSVGPSLLTSASV
1110 1120 1130 1140 1150 1160
1250 1260 1270 1280
pF1KE3 APAQYQHQFATQSYIGSSRGSTIYTGYPLSPTKISQYSYL
::::::::::::::::::::::::::::::::::::::::
XP_016 APAQYQHQFATQSYIGSSRGSTIYTGYPLSPTKISQYSYL
1170 1180 1190 1200
>>XP_005270668 (OMIM: 608003) PREDICTED: homeodomain-int (1256 aa)
initn: 7099 init1: 7099 opt: 7163 Z-score: 2689.4 bits: 509.8 E(85289): 4.6e-143
Smith-Waterman score: 8222; 98.0% identity (98.0% similar) in 1281 aa overlap (1-1281:1-1256)
10 20 30 40 50 60
pF1KE3 MTFYSWIPYHRQAPLNHRRVCSAEGAGSPGPALDPRWLPTEAHLLEAHRLLLQSVLCDRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MTFYSWIPYHRQAPLNHRRVCSAEGAGSPGPALDPRWLPTEAHLLEAHRLLLQSVLCDRP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 RESIQLHFRLSMASQLQVFSPPSVSSSAFCSAKKLKIEPSGWDVSGQSSNDKYYTHSKTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RESIQLHFRLSMASQLQVFSPPSVSSSAFCSAKKLKIEPSGWDVSGQSSNDKYYTHSKTL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 PATQGQANSSHQVANFNIPAYDQGLLLPAPAVEHIVVTAADSSGSAATSTFQSSQTLTHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PATQGQANSSHQVANFNIPAYDQGLLLPAPAVEHIVVTAADSSGSAATSTFQSSQTLTHR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 SNVSLLEPYQKCGLKRKSEEVDSNGSVQIIEEHPPLMLQNRTVVGAAATTTTVTTKSSSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SNVSLLEPYQKCGLKRKSEEVDSNGSVQIIEEHPPLMLQNRTVVGAAATTTTVTTKSSSS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 SGEGDYQLVQHEILCSMTNSYEVLEFLGRGTFGQVAKCWKRSTKEIVAIKILKNHPSYAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SGEGDYQLVQHEILCSMTNSYEVLEFLGRGTFGQVAKCWKRSTKEIVAIKILKNHPSYAR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 QGQIEVSILSRLSSENADEYNFVRSYECFQHKNHTCLVFEMLEQNLYDFLKQNKFSPLPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QGQIEVSILSRLSSENADEYNFVRSYECFQHKNHTCLVFEMLEQNLYDFLKQNKFSPLPL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 KYIRPILQQVATALMKLKSLGLIHADLKPENIMLVDPVRQPYRVKVIDFGSASHVSKAVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KYIRPILQQVATALMKLKSLGLIHADLKPENIMLVDPVRQPYRVKVIDFGSASHVSKAVC
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 STYLQSRYYRAPEIILGLPFCEAIDMWSLGCVIAELFLGWPLYPGASEYDQIRYISQTQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 STYLQSRYYRAPEIILGLPFCEAIDMWSLGCVIAELFLGWPLYPGASEYDQIRYISQTQG
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 LPAEYLLSAGTKTTRFFNRDPNLGYPLWRLKTPEEHELETGIKSKEARKYIFNCLDDMAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LPAEYLLSAGTKTTRFFNRDPNLGYPLWRLKTPEEHELETGIKSKEARKYIFNCLDDMAQ
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 VNMSTDLEGTDMLAEKADRREYIDLLKKMLTIDADKRITPLKTLNHQFVTMTHLLDFPHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VNMSTDLEGTDMLAEKADRREYIDLLKKMLTIDADKRITPLKTLNHQFVTMTHLLDFPHS
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 NHVKSCFQNMEICKRRVHMYDTVSQIKSPFTTHVAPNTSTNLTMSFSNQLNTVHNQASVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NHVKSCFQNMEICKRRVHMYDTVSQIKSPFTTHVAPNTSTNLTMSFSNQLNTVHNQASVL
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 ASSSTAAAATLSLANSDVSLLNYQSALYPSSAAPVPGVAQQGVSLQPGTTQICTQTDPFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ASSSTAAAATLSLANSDVSLLNYQSALYPSSAAPVPGVAQQGVSLQPGTTQICTQTDPFQ
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 QTFIVCPPAFQTGLQATTKHSGFPVRMDNAVPIVPQAPAAQPLQIQSGVLTQGSCTPLMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QTFIVCPPAFQTGLQATTKHSGFPVRMDNAVPIVPQAPAAQPLQIQSGVLTQGSCTPLMV
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE3 ATLHPQVATITPQYAVPFTLSCAAGRPALVEQTAAVLQAWPGGTQQILLPSTWQQLPGVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ATLHPQVATITPQYAVPFTLSCAAGRPALVEQTAAVLQAWPGGTQQILLPSTWQQLPGVA
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE3 LHNSVQPTAMIPEAMGSGQQLADWRNAHSHGNQYSTIMQQPSLLTNHVTLATAQPLNVGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LHNSVQPTAMIPEAMGSGQQLADWRNAHSHGNQYSTIMQQPSLLTNHVTLATAQPLNVGV
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE3 AHVVRQQQSSSLPSKKNKQSAPVSSKSSLDVLPSQVYSLVGSSPLRTTSSYNSLVPVQDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AHVVRQQQSSSLPSKKNKQSAPVSSKSSLDVLPSQVYSLVGSSPLRTTSSYNSLVPVQDQ
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE3 HQPIIIPDTPSPPVSVITIRSDTDEEEDNKYKPSSSGLKPRSNVISYVTVNDSPDSDSSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HQPIIIPDTPSPPVSVITIRSDTDEEEDNKYKPSSSGLKPRSNVISYVTVNDSPDSDSSL
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE3 SSPYSTDTLSALRGNSGSVLEGPGRVVADGTGTRTIIVPPLKTQLGDCTVATQASGLLSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SSPYSTDTLSALRGNSGSVLEGPGRVVADGTGTRTIIVPPLKTQLGDCTVATQASG----
1030 1040 1050 1060 1070
1090 1100 1110 1120 1130 1140
pF1KE3 KTKPVASVSGQSSGCCITPTGYRAQRGGTSAAQPLNLSQNQQSSAAPTSQERSSNPAPRR
:::::::::::::::::::::::::::::::::::::::
XP_005 ---------------------YRAQRGGTSAAQPLNLSQNQQSSAAPTSQERSSNPAPRR
1080 1090 1100 1110
1150 1160 1170 1180 1190 1200
pF1KE3 QQAFVAPLSQAPYTFQHGSPLHSTGHPHLAPAPAHLPSQAHLYTYAAPTSAAALGSTSSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QQAFVAPLSQAPYTFQHGSPLHSTGHPHLAPAPAHLPSQAHLYTYAAPTSAAALGSTSSI
1120 1130 1140 1150 1160 1170
1210 1220 1230 1240 1250 1260
pF1KE3 AHLFSPQGSSRHAAAYTTHPSTLVHQVPVSVGPSLLTSASVAPAQYQHQFATQSYIGSSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AHLFSPQGSSRHAAAYTTHPSTLVHQVPVSVGPSLLTSASVAPAQYQHQFATQSYIGSSR
1180 1190 1200 1210 1220 1230
1270 1280
pF1KE3 GSTIYTGYPLSPTKISQYSYL
:::::::::::::::::::::
XP_005 GSTIYTGYPLSPTKISQYSYL
1240 1250
>>NP_689909 (OMIM: 608003) homeodomain-interacting prote (1075 aa)
initn: 6873 init1: 6873 opt: 6873 Z-score: 2582.5 bits: 489.8 E(85289): 4.2e-137
Smith-Waterman score: 6873; 100.0% identity (100.0% similar) in 1048 aa overlap (72-1119:1-1048)
50 60 70 80 90 100
pF1KE3 AHLLEAHRLLLQSVLCDRPRESIQLHFRLSMASQLQVFSPPSVSSSAFCSAKKLKIEPSG
::::::::::::::::::::::::::::::
NP_689 MASQLQVFSPPSVSSSAFCSAKKLKIEPSG
10 20 30
110 120 130 140 150 160
pF1KE3 WDVSGQSSNDKYYTHSKTLPATQGQANSSHQVANFNIPAYDQGLLLPAPAVEHIVVTAAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 WDVSGQSSNDKYYTHSKTLPATQGQANSSHQVANFNIPAYDQGLLLPAPAVEHIVVTAAD
40 50 60 70 80 90
170 180 190 200 210 220
pF1KE3 SSGSAATSTFQSSQTLTHRSNVSLLEPYQKCGLKRKSEEVDSNGSVQIIEEHPPLMLQNR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 SSGSAATSTFQSSQTLTHRSNVSLLEPYQKCGLKRKSEEVDSNGSVQIIEEHPPLMLQNR
100 110 120 130 140 150
230 240 250 260 270 280
pF1KE3 TVVGAAATTTTVTTKSSSSSGEGDYQLVQHEILCSMTNSYEVLEFLGRGTFGQVAKCWKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 TVVGAAATTTTVTTKSSSSSGEGDYQLVQHEILCSMTNSYEVLEFLGRGTFGQVAKCWKR
160 170 180 190 200 210
290 300 310 320 330 340
pF1KE3 STKEIVAIKILKNHPSYARQGQIEVSILSRLSSENADEYNFVRSYECFQHKNHTCLVFEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 STKEIVAIKILKNHPSYARQGQIEVSILSRLSSENADEYNFVRSYECFQHKNHTCLVFEM
220 230 240 250 260 270
350 360 370 380 390 400
pF1KE3 LEQNLYDFLKQNKFSPLPLKYIRPILQQVATALMKLKSLGLIHADLKPENIMLVDPVRQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 LEQNLYDFLKQNKFSPLPLKYIRPILQQVATALMKLKSLGLIHADLKPENIMLVDPVRQP
280 290 300 310 320 330
410 420 430 440 450 460
pF1KE3 YRVKVIDFGSASHVSKAVCSTYLQSRYYRAPEIILGLPFCEAIDMWSLGCVIAELFLGWP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 YRVKVIDFGSASHVSKAVCSTYLQSRYYRAPEIILGLPFCEAIDMWSLGCVIAELFLGWP
340 350 360 370 380 390
470 480 490 500 510 520
pF1KE3 LYPGASEYDQIRYISQTQGLPAEYLLSAGTKTTRFFNRDPNLGYPLWRLKTPEEHELETG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 LYPGASEYDQIRYISQTQGLPAEYLLSAGTKTTRFFNRDPNLGYPLWRLKTPEEHELETG
400 410 420 430 440 450
530 540 550 560 570 580
pF1KE3 IKSKEARKYIFNCLDDMAQVNMSTDLEGTDMLAEKADRREYIDLLKKMLTIDADKRITPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 IKSKEARKYIFNCLDDMAQVNMSTDLEGTDMLAEKADRREYIDLLKKMLTIDADKRITPL
460 470 480 490 500 510
590 600 610 620 630 640
pF1KE3 KTLNHQFVTMTHLLDFPHSNHVKSCFQNMEICKRRVHMYDTVSQIKSPFTTHVAPNTSTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 KTLNHQFVTMTHLLDFPHSNHVKSCFQNMEICKRRVHMYDTVSQIKSPFTTHVAPNTSTN
520 530 540 550 560 570
650 660 670 680 690 700
pF1KE3 LTMSFSNQLNTVHNQASVLASSSTAAAATLSLANSDVSLLNYQSALYPSSAAPVPGVAQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 LTMSFSNQLNTVHNQASVLASSSTAAAATLSLANSDVSLLNYQSALYPSSAAPVPGVAQQ
580 590 600 610 620 630
710 720 730 740 750 760
pF1KE3 GVSLQPGTTQICTQTDPFQQTFIVCPPAFQTGLQATTKHSGFPVRMDNAVPIVPQAPAAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 GVSLQPGTTQICTQTDPFQQTFIVCPPAFQTGLQATTKHSGFPVRMDNAVPIVPQAPAAQ
640 650 660 670 680 690
770 780 790 800 810 820
pF1KE3 PLQIQSGVLTQGSCTPLMVATLHPQVATITPQYAVPFTLSCAAGRPALVEQTAAVLQAWP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 PLQIQSGVLTQGSCTPLMVATLHPQVATITPQYAVPFTLSCAAGRPALVEQTAAVLQAWP
700 710 720 730 740 750
830 840 850 860 870 880
pF1KE3 GGTQQILLPSTWQQLPGVALHNSVQPTAMIPEAMGSGQQLADWRNAHSHGNQYSTIMQQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 GGTQQILLPSTWQQLPGVALHNSVQPTAMIPEAMGSGQQLADWRNAHSHGNQYSTIMQQP
760 770 780 790 800 810
890 900 910 920 930 940
pF1KE3 SLLTNHVTLATAQPLNVGVAHVVRQQQSSSLPSKKNKQSAPVSSKSSLDVLPSQVYSLVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 SLLTNHVTLATAQPLNVGVAHVVRQQQSSSLPSKKNKQSAPVSSKSSLDVLPSQVYSLVG
820 830 840 850 860 870
950 960 970 980 990 1000
pF1KE3 SSPLRTTSSYNSLVPVQDQHQPIIIPDTPSPPVSVITIRSDTDEEEDNKYKPSSSGLKPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 SSPLRTTSSYNSLVPVQDQHQPIIIPDTPSPPVSVITIRSDTDEEEDNKYKPSSSGLKPR
880 890 900 910 920 930
1010 1020 1030 1040 1050 1060
pF1KE3 SNVISYVTVNDSPDSDSSLSSPYSTDTLSALRGNSGSVLEGPGRVVADGTGTRTIIVPPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 SNVISYVTVNDSPDSDSSLSSPYSTDTLSALRGNSGSVLEGPGRVVADGTGTRTIIVPPL
940 950 960 970 980 990
1070 1080 1090 1100 1110 1120
pF1KE3 KTQLGDCTVATQASGLLSNKTKPVASVSGQSSGCCITPTGYRAQRGGTSAAQPLNLSQNQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 KTQLGDCTVATQASGLLSNKTKPVASVSGQSSGCCITPTGYRAQRGGTSAAQPLNLSQVS
1000 1010 1020 1030 1040 1050
1130 1140 1150 1160 1170 1180
pF1KE3 QSSAAPTSQERSSNPAPRRQQAFVAPLSQAPYTFQHGSPLHSTGHPHLAPAPAHLPSQAH
NP_689 AMGYCLLFGPCTVVTFWRTLLLAGC
1060 1070
>>NP_938010 (OMIM: 608003) homeodomain-interacting prote (836 aa)
initn: 5505 init1: 5505 opt: 5505 Z-score: 2075.7 bits: 395.7 E(85289): 7.1e-109
Smith-Waterman score: 5505; 100.0% identity (100.0% similar) in 836 aa overlap (446-1281:1-836)
420 430 440 450 460 470
pF1KE3 SKAVCSTYLQSRYYRAPEIILGLPFCEAIDMWSLGCVIAELFLGWPLYPGASEYDQIRYI
::::::::::::::::::::::::::::::
NP_938 MWSLGCVIAELFLGWPLYPGASEYDQIRYI
10 20 30
480 490 500 510 520 530
pF1KE3 SQTQGLPAEYLLSAGTKTTRFFNRDPNLGYPLWRLKTPEEHELETGIKSKEARKYIFNCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 SQTQGLPAEYLLSAGTKTTRFFNRDPNLGYPLWRLKTPEEHELETGIKSKEARKYIFNCL
40 50 60 70 80 90
540 550 560 570 580 590
pF1KE3 DDMAQVNMSTDLEGTDMLAEKADRREYIDLLKKMLTIDADKRITPLKTLNHQFVTMTHLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 DDMAQVNMSTDLEGTDMLAEKADRREYIDLLKKMLTIDADKRITPLKTLNHQFVTMTHLL
100 110 120 130 140 150
600 610 620 630 640 650
pF1KE3 DFPHSNHVKSCFQNMEICKRRVHMYDTVSQIKSPFTTHVAPNTSTNLTMSFSNQLNTVHN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 DFPHSNHVKSCFQNMEICKRRVHMYDTVSQIKSPFTTHVAPNTSTNLTMSFSNQLNTVHN
160 170 180 190 200 210
660 670 680 690 700 710
pF1KE3 QASVLASSSTAAAATLSLANSDVSLLNYQSALYPSSAAPVPGVAQQGVSLQPGTTQICTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 QASVLASSSTAAAATLSLANSDVSLLNYQSALYPSSAAPVPGVAQQGVSLQPGTTQICTQ
220 230 240 250 260 270
720 730 740 750 760 770
pF1KE3 TDPFQQTFIVCPPAFQTGLQATTKHSGFPVRMDNAVPIVPQAPAAQPLQIQSGVLTQGSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 TDPFQQTFIVCPPAFQTGLQATTKHSGFPVRMDNAVPIVPQAPAAQPLQIQSGVLTQGSC
280 290 300 310 320 330
780 790 800 810 820 830
pF1KE3 TPLMVATLHPQVATITPQYAVPFTLSCAAGRPALVEQTAAVLQAWPGGTQQILLPSTWQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 TPLMVATLHPQVATITPQYAVPFTLSCAAGRPALVEQTAAVLQAWPGGTQQILLPSTWQQ
340 350 360 370 380 390
840 850 860 870 880 890
pF1KE3 LPGVALHNSVQPTAMIPEAMGSGQQLADWRNAHSHGNQYSTIMQQPSLLTNHVTLATAQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 LPGVALHNSVQPTAMIPEAMGSGQQLADWRNAHSHGNQYSTIMQQPSLLTNHVTLATAQP
400 410 420 430 440 450
900 910 920 930 940 950
pF1KE3 LNVGVAHVVRQQQSSSLPSKKNKQSAPVSSKSSLDVLPSQVYSLVGSSPLRTTSSYNSLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 LNVGVAHVVRQQQSSSLPSKKNKQSAPVSSKSSLDVLPSQVYSLVGSSPLRTTSSYNSLV
460 470 480 490 500 510
960 970 980 990 1000 1010
pF1KE3 PVQDQHQPIIIPDTPSPPVSVITIRSDTDEEEDNKYKPSSSGLKPRSNVISYVTVNDSPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 PVQDQHQPIIIPDTPSPPVSVITIRSDTDEEEDNKYKPSSSGLKPRSNVISYVTVNDSPD
520 530 540 550 560 570
1020 1030 1040 1050 1060 1070
pF1KE3 SDSSLSSPYSTDTLSALRGNSGSVLEGPGRVVADGTGTRTIIVPPLKTQLGDCTVATQAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 SDSSLSSPYSTDTLSALRGNSGSVLEGPGRVVADGTGTRTIIVPPLKTQLGDCTVATQAS
580 590 600 610 620 630
1080 1090 1100 1110 1120 1130
pF1KE3 GLLSNKTKPVASVSGQSSGCCITPTGYRAQRGGTSAAQPLNLSQNQQSSAAPTSQERSSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 GLLSNKTKPVASVSGQSSGCCITPTGYRAQRGGTSAAQPLNLSQNQQSSAAPTSQERSSN
640 650 660 670 680 690
1140 1150 1160 1170 1180 1190
pF1KE3 PAPRRQQAFVAPLSQAPYTFQHGSPLHSTGHPHLAPAPAHLPSQAHLYTYAAPTSAAALG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 PAPRRQQAFVAPLSQAPYTFQHGSPLHSTGHPHLAPAPAHLPSQAHLYTYAAPTSAAALG
700 710 720 730 740 750
1200 1210 1220 1230 1240 1250
pF1KE3 STSSIAHLFSPQGSSRHAAAYTTHPSTLVHQVPVSVGPSLLTSASVAPAQYQHQFATQSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_938 STSSIAHLFSPQGSSRHAAAYTTHPSTLVHQVPVSVGPSLLTSASVAPAQYQHQFATQSY
760 770 780 790 800 810
1260 1270 1280
pF1KE3 IGSSRGSTIYTGYPLSPTKISQYSYL
::::::::::::::::::::::::::
NP_938 IGSSRGSTIYTGYPLSPTKISQYSYL
820 830
>>NP_852003 (OMIM: 608003) homeodomain-interacting prote (816 aa)
initn: 5317 init1: 5317 opt: 5317 Z-score: 2006.0 bits: 382.7 E(85289): 5.4e-105
Smith-Waterman score: 5317; 100.0% identity (100.0% similar) in 811 aa overlap (471-1281:6-816)
450 460 470 480 490 500
pF1KE3 CEAIDMWSLGCVIAELFLGWPLYPGASEYDQIRYISQTQGLPAEYLLSAGTKTTRFFNRD
::::::::::::::::::::::::::::::
NP_852 MVLMFQIRYISQTQGLPAEYLLSAGTKTTRFFNRD
10 20 30
510 520 530 540 550 560
pF1KE3 PNLGYPLWRLKTPEEHELETGIKSKEARKYIFNCLDDMAQVNMSTDLEGTDMLAEKADRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 PNLGYPLWRLKTPEEHELETGIKSKEARKYIFNCLDDMAQVNMSTDLEGTDMLAEKADRR
40 50 60 70 80 90
570 580 590 600 610 620
pF1KE3 EYIDLLKKMLTIDADKRITPLKTLNHQFVTMTHLLDFPHSNHVKSCFQNMEICKRRVHMY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 EYIDLLKKMLTIDADKRITPLKTLNHQFVTMTHLLDFPHSNHVKSCFQNMEICKRRVHMY
100 110 120 130 140 150
630 640 650 660 670 680
pF1KE3 DTVSQIKSPFTTHVAPNTSTNLTMSFSNQLNTVHNQASVLASSSTAAAATLSLANSDVSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 DTVSQIKSPFTTHVAPNTSTNLTMSFSNQLNTVHNQASVLASSSTAAAATLSLANSDVSL
160 170 180 190 200 210
690 700 710 720 730 740
pF1KE3 LNYQSALYPSSAAPVPGVAQQGVSLQPGTTQICTQTDPFQQTFIVCPPAFQTGLQATTKH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 LNYQSALYPSSAAPVPGVAQQGVSLQPGTTQICTQTDPFQQTFIVCPPAFQTGLQATTKH
220 230 240 250 260 270
750 760 770 780 790 800
pF1KE3 SGFPVRMDNAVPIVPQAPAAQPLQIQSGVLTQGSCTPLMVATLHPQVATITPQYAVPFTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 SGFPVRMDNAVPIVPQAPAAQPLQIQSGVLTQGSCTPLMVATLHPQVATITPQYAVPFTL
280 290 300 310 320 330
810 820 830 840 850 860
pF1KE3 SCAAGRPALVEQTAAVLQAWPGGTQQILLPSTWQQLPGVALHNSVQPTAMIPEAMGSGQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 SCAAGRPALVEQTAAVLQAWPGGTQQILLPSTWQQLPGVALHNSVQPTAMIPEAMGSGQQ
340 350 360 370 380 390
870 880 890 900 910 920
pF1KE3 LADWRNAHSHGNQYSTIMQQPSLLTNHVTLATAQPLNVGVAHVVRQQQSSSLPSKKNKQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 LADWRNAHSHGNQYSTIMQQPSLLTNHVTLATAQPLNVGVAHVVRQQQSSSLPSKKNKQS
400 410 420 430 440 450
930 940 950 960 970 980
pF1KE3 APVSSKSSLDVLPSQVYSLVGSSPLRTTSSYNSLVPVQDQHQPIIIPDTPSPPVSVITIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 APVSSKSSLDVLPSQVYSLVGSSPLRTTSSYNSLVPVQDQHQPIIIPDTPSPPVSVITIR
460 470 480 490 500 510
990 1000 1010 1020 1030 1040
pF1KE3 SDTDEEEDNKYKPSSSGLKPRSNVISYVTVNDSPDSDSSLSSPYSTDTLSALRGNSGSVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 SDTDEEEDNKYKPSSSGLKPRSNVISYVTVNDSPDSDSSLSSPYSTDTLSALRGNSGSVL
520 530 540 550 560 570
1050 1060 1070 1080 1090 1100
pF1KE3 EGPGRVVADGTGTRTIIVPPLKTQLGDCTVATQASGLLSNKTKPVASVSGQSSGCCITPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 EGPGRVVADGTGTRTIIVPPLKTQLGDCTVATQASGLLSNKTKPVASVSGQSSGCCITPT
580 590 600 610 620 630
1110 1120 1130 1140 1150 1160
pF1KE3 GYRAQRGGTSAAQPLNLSQNQQSSAAPTSQERSSNPAPRRQQAFVAPLSQAPYTFQHGSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 GYRAQRGGTSAAQPLNLSQNQQSSAAPTSQERSSNPAPRRQQAFVAPLSQAPYTFQHGSP
640 650 660 670 680 690
1170 1180 1190 1200 1210 1220
pF1KE3 LHSTGHPHLAPAPAHLPSQAHLYTYAAPTSAAALGSTSSIAHLFSPQGSSRHAAAYTTHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 LHSTGHPHLAPAPAHLPSQAHLYTYAAPTSAAALGSTSSIAHLFSPQGSSRHAAAYTTHP
700 710 720 730 740 750
1230 1240 1250 1260 1270 1280
pF1KE3 STLVHQVPVSVGPSLLTSASVAPAQYQHQFATQSYIGSSRGSTIYTGYPLSPTKISQYSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_852 STLVHQVPVSVGPSLLTSASVAPAQYQHQFATQSYIGSSRGSTIYTGYPLSPTKISQYSY
760 770 780 790 800 810
pF1KE3 L
:
NP_852 L
1281 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 16:39:04 2016 done: Mon Nov 7 16:39:06 2016
Total Scan time: 17.860 Total Display time: 0.540
Function used was FASTA [36.3.4 Apr, 2011]