Result of FASTA (omim) for
pFN21AE3427
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3427, 602 aa
1>>>pF1KE3427 602 - 602 aa - 602 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.6986+/-0.000366; mu= 3.5774+/- 0.023
mean_var=170.5797+/-36.414, 0's: 0 Z-trim(119.0): 108 B-trim: 3479 in 2/56
Lambda= 0.098200
statistics sampled from 32405 (32514) to 32405 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.717), E-opt: 0.2 (0.381), width: 16
Scan time: 9.670
The best scores are: opt bits E(85289)
NP_001317606 (OMIM: 260660,604127) T-box transcrip ( 602) 4072 589.2 1.3e-167
NP_689593 (OMIM: 260660,604127) T-box transcriptio ( 496) 3387 492.1 1.9e-138
XP_005271218 (OMIM: 260660,604127) PREDICTED: T-bo ( 635) 2306 339.0 2.9e-92
XP_011540354 (OMIM: 260660,604127) PREDICTED: T-bo ( 320) 1773 263.3 8.7e-70
NP_001073977 (OMIM: 143100,143400,604613) T-box tr ( 607) 1557 232.9 2.4e-60
XP_016866961 (OMIM: 143100,143400,604613) PREDICTE ( 449) 1452 217.9 5.7e-56
XP_011534550 (OMIM: 143100,143400,604613) PREDICTE ( 377) 1401 210.7 7.3e-54
XP_006715665 (OMIM: 143100,143400,604613) PREDICTE ( 364) 1396 210.0 1.2e-53
XP_011534549 (OMIM: 143100,143400,604613) PREDICTE ( 379) 1390 209.1 2.2e-53
XP_011534551 (OMIM: 143100,143400,604613) PREDICTE ( 372) 1388 208.8 2.6e-53
XP_016866962 (OMIM: 143100,143400,604613) PREDICTE ( 376) 1388 208.8 2.6e-53
NP_058650 (OMIM: 300307,302905,303400) T-box trans ( 520) 1265 191.5 6.1e-48
NP_001103348 (OMIM: 300307,302905,303400) T-box tr ( 520) 1265 191.5 6.1e-48
XP_005262193 (OMIM: 300307,302905,303400) PREDICTE ( 521) 1262 191.1 8.2e-48
XP_006724720 (OMIM: 300307,302905,303400) PREDICTE ( 350) 1099 167.9 5.2e-41
NP_001103349 (OMIM: 300307,302905,303400) T-box tr ( 400) 1066 163.2 1.5e-39
NP_001290404 (OMIM: 300307,302905,303400) T-box tr ( 400) 1066 163.2 1.5e-39
XP_011529274 (OMIM: 300307,302905,303400) PREDICTE ( 400) 1066 163.2 1.5e-39
NP_001071121 (OMIM: 606061,611363) T-box transcrip ( 447) 931 144.1 9.4e-34
NP_001159692 (OMIM: 606061,611363) T-box transcrip ( 297) 863 134.4 5.3e-31
NP_005983 (OMIM: 187500,188400,192430,217095,60205 ( 372) 840 131.2 6.1e-30
XP_006724375 (OMIM: 187500,188400,192430,217095,60 ( 495) 832 130.1 1.7e-29
NP_542378 (OMIM: 187500,188400,192430,217095,60205 ( 495) 832 130.1 1.7e-29
XP_016884415 (OMIM: 187500,188400,192430,217095,60 ( 495) 832 130.1 1.7e-29
XP_016884414 (OMIM: 187500,188400,192430,217095,60 ( 545) 832 130.1 1.9e-29
NP_542377 (OMIM: 187500,188400,192430,217095,60205 ( 398) 824 128.9 3.1e-29
XP_016884417 (OMIM: 187500,188400,192430,217095,60 ( 448) 824 129.0 3.4e-29
XP_011544228 (OMIM: 122600,602427) PREDICTED: T-bo ( 436) 803 126.0 2.6e-28
XP_005255580 (OMIM: 122600,602427) PREDICTED: T-bo ( 436) 803 126.0 2.6e-28
XP_016879103 (OMIM: 122600,602427) PREDICTED: T-bo ( 436) 803 126.0 2.6e-28
NP_004599 (OMIM: 122600,602427) T-box transcriptio ( 436) 803 126.0 2.6e-28
XP_011543294 (OMIM: 604648) PREDICTED: T-box trans ( 430) 789 124.0 1e-27
NP_852259 (OMIM: 142900,601620) T-box transcriptio ( 518) 790 124.2 1.1e-27
NP_000183 (OMIM: 142900,601620) T-box transcriptio ( 518) 790 124.2 1.1e-27
XP_016875401 (OMIM: 142900,601620) PREDICTED: T-bo ( 534) 790 124.2 1.1e-27
NP_005986 (OMIM: 604648) T-box transcription facto ( 385) 787 123.7 1.1e-27
NP_542448 (OMIM: 142900,601620) T-box transcriptio ( 468) 783 123.2 2e-27
NP_060958 (OMIM: 147891,601719) T-box transcriptio ( 545) 775 122.1 5e-27
XP_011523793 (OMIM: 147891,601719) PREDICTED: T-bo ( 608) 775 122.1 5.5e-27
NP_001308049 (OMIM: 147891,601719) T-box transcrip ( 546) 772 121.6 6.7e-27
XP_011523792 (OMIM: 147891,601719) PREDICTED: T-bo ( 609) 772 121.7 7.4e-27
XP_011523797 (OMIM: 147891,601719) PREDICTED: T-bo ( 417) 763 120.3 1.3e-26
NP_005985 (OMIM: 600747) T-box transcription facto ( 712) 720 114.3 1.4e-24
NP_005987 (OMIM: 181450,601621) T-box transcriptio ( 723) 718 114.1 1.7e-24
XP_016877522 (OMIM: 616061) PREDICTED: MAX gene-as (1439) 683 109.2 9.6e-23
XP_011519703 (OMIM: 616061) PREDICTED: MAX gene-as (1549) 683 109.3 1e-22
XP_016877519 (OMIM: 616061) PREDICTED: MAX gene-as (2207) 683 109.3 1.4e-22
NP_001074010 (OMIM: 616061) MAX gene-associated pr (2856) 683 109.4 1.7e-22
XP_005254310 (OMIM: 616061) PREDICTED: MAX gene-as (2906) 683 109.4 1.8e-22
XP_005254309 (OMIM: 616061) PREDICTED: MAX gene-as (2956) 683 109.4 1.8e-22
>>NP_001317606 (OMIM: 260660,604127) T-box transcription (602 aa)
initn: 4072 init1: 4072 opt: 4072 Z-score: 3129.9 bits: 589.2 E(85289): 1.3e-167
Smith-Waterman score: 4072; 100.0% identity (100.0% similar) in 602 aa overlap (1-602:1-602)
10 20 30 40 50 60
pF1KE3 MSERRRSAVALSSRAHAFSVEALIGSNKKRKLRDWEEKGLDLSMEALSPAGPLGDTEDAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSERRRSAVALSSRAHAFSVEALIGSNKKRKLRDWEEKGLDLSMEALSPAGPLGDTEDAA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 AHGLEPHPDSEQSTGSDSEVLTERTSCSFSTHTDLASGAAGPVPAAMSSMEEIQVELQCA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AHGLEPHPDSEQSTGSDSEVLTERTSCSFSTHTDLASGAAGPVPAAMSSMEEIQVELQCA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 DLWKRFHDIGTEMIITKAGRRMFPAMRVKITGLDPHQQYYIAMDIVPVDNKRYRYVYHSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DLWKRFHDIGTEMIITKAGRRMFPAMRVKITGLDPHQQYYIAMDIVPVDNKRYRYVYHSS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 KWMVAGNADSPVPPRVYIHPDSLASGDTWMRQVVSFDKLKLTNNELDDQGHIILHSMHKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KWMVAGNADSPVPPRVYIHPDSLASGDTWMRQVVSFDKLKLTNNELDDQGHIILHSMHKY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 QPRVHVIRKDFSSDLSPTKPVPVGDGVKTFNFPETVFTTVTAYQNQQITRLKIDRNPFAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QPRVHVIRKDFSSDLSPTKPVPVGDGVKTFNFPETVFTTVTAYQNQQITRLKIDRNPFAK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 GFRDSGRNRTGLEAIMETYAFWRPPVRTLTFEDFTTMQKQQGGSTGTSPTTSSTGTPSPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GFRDSGRNRTGLEAIMETYAFWRPPVRTLTFEDFTTMQKQQGGSTGTSPTTSSTGTPSPS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 ASSHLLSPSCSPPTFHLAPNTFNVGCRESQLCNLNLSDYPPCARSNMAALQSYPGLSDSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ASSHLLSPSCSPPTFHLAPNTFNVGCRESQLCNLNLSDYPPCARSNMAALQSYPGLSDSG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 YNRLQSGTTSATQPSETFMPQRTPSLISGIPTPPSLPGNSKMEAYGGQLGSFPTSQFQYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YNRLQSGTTSATQPSETFMPQRTPSLISGIPTPPSLPGNSKMEAYGGQLGSFPTSQFQYV
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 MQAGNAASSSSSPHMFGGSHMQQSSYNAFSLHNPYNLYGYNFPTSPRLAASPEKLSASQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MQAGNAASSSSSPHMFGGSHMQQSSYNAFSLHNPYNLYGYNFPTSPRLAASPEKLSASQS
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 TLLCSSPSNGAFGERQYLPSGMEHSMHMISPSPNNQQATNTCDGRQYGAVPGSSSQMSVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLLCSSPSNGAFGERQYLPSGMEHSMHMISPSPNNQQATNTCDGRQYGAVPGSSSQMSVH
550 560 570 580 590 600
pF1KE3 MV
::
NP_001 MV
>>NP_689593 (OMIM: 260660,604127) T-box transcription fa (496 aa)
initn: 3387 init1: 3387 opt: 3387 Z-score: 2606.7 bits: 492.1 E(85289): 1.9e-138
Smith-Waterman score: 3387; 100.0% identity (100.0% similar) in 496 aa overlap (107-602:1-496)
80 90 100 110 120 130
pF1KE3 DSEVLTERTSCSFSTHTDLASGAAGPVPAAMSSMEEIQVELQCADLWKRFHDIGTEMIIT
::::::::::::::::::::::::::::::
NP_689 MSSMEEIQVELQCADLWKRFHDIGTEMIIT
10 20 30
140 150 160 170 180 190
pF1KE3 KAGRRMFPAMRVKITGLDPHQQYYIAMDIVPVDNKRYRYVYHSSKWMVAGNADSPVPPRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 KAGRRMFPAMRVKITGLDPHQQYYIAMDIVPVDNKRYRYVYHSSKWMVAGNADSPVPPRV
40 50 60 70 80 90
200 210 220 230 240 250
pF1KE3 YIHPDSLASGDTWMRQVVSFDKLKLTNNELDDQGHIILHSMHKYQPRVHVIRKDFSSDLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 YIHPDSLASGDTWMRQVVSFDKLKLTNNELDDQGHIILHSMHKYQPRVHVIRKDFSSDLS
100 110 120 130 140 150
260 270 280 290 300 310
pF1KE3 PTKPVPVGDGVKTFNFPETVFTTVTAYQNQQITRLKIDRNPFAKGFRDSGRNRTGLEAIM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 PTKPVPVGDGVKTFNFPETVFTTVTAYQNQQITRLKIDRNPFAKGFRDSGRNRTGLEAIM
160 170 180 190 200 210
320 330 340 350 360 370
pF1KE3 ETYAFWRPPVRTLTFEDFTTMQKQQGGSTGTSPTTSSTGTPSPSASSHLLSPSCSPPTFH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 ETYAFWRPPVRTLTFEDFTTMQKQQGGSTGTSPTTSSTGTPSPSASSHLLSPSCSPPTFH
220 230 240 250 260 270
380 390 400 410 420 430
pF1KE3 LAPNTFNVGCRESQLCNLNLSDYPPCARSNMAALQSYPGLSDSGYNRLQSGTTSATQPSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 LAPNTFNVGCRESQLCNLNLSDYPPCARSNMAALQSYPGLSDSGYNRLQSGTTSATQPSE
280 290 300 310 320 330
440 450 460 470 480 490
pF1KE3 TFMPQRTPSLISGIPTPPSLPGNSKMEAYGGQLGSFPTSQFQYVMQAGNAASSSSSPHMF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 TFMPQRTPSLISGIPTPPSLPGNSKMEAYGGQLGSFPTSQFQYVMQAGNAASSSSSPHMF
340 350 360 370 380 390
500 510 520 530 540 550
pF1KE3 GGSHMQQSSYNAFSLHNPYNLYGYNFPTSPRLAASPEKLSASQSTLLCSSPSNGAFGERQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 GGSHMQQSSYNAFSLHNPYNLYGYNFPTSPRLAASPEKLSASQSTLLCSSPSNGAFGERQ
400 410 420 430 440 450
560 570 580 590 600
pF1KE3 YLPSGMEHSMHMISPSPNNQQATNTCDGRQYGAVPGSSSQMSVHMV
::::::::::::::::::::::::::::::::::::::::::::::
NP_689 YLPSGMEHSMHMISPSPNNQQATNTCDGRQYGAVPGSSSQMSVHMV
460 470 480 490
>>XP_005271218 (OMIM: 260660,604127) PREDICTED: T-box tr (635 aa)
initn: 4050 init1: 2291 opt: 2306 Z-score: 1777.4 bits: 339.0 E(85289): 2.9e-92
Smith-Waterman score: 3988; 94.6% identity (94.8% similar) in 635 aa overlap (1-602:1-635)
10 20 30 40 50 60
pF1KE3 MSERRRSAVALSSRAHAFSVEALIGSNKKRKLRDWEEKGLDLSMEALSPAGPLGDTEDAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MSERRRSAVALSSRAHAFSVEALIGSNKKRKLRDWEEKGLDLSMEALSPAGPLGDTEDAA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 AHGLEPHPDSEQSTGSDSEVLTERTSCSFSTHTDLASGAAGPVPAAMSSMEEIQVELQCA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AHGLEPHPDSEQSTGSDSEVLTERTSCSFSTHTDLASGAAGPVPAAMSSMEEIQVELQCA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 DLWKRFHDIGTEMIITKAGRRMFPAMRVKITGLDPHQQYYIAMDIVPVDNKRYRYVYHSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DLWKRFHDIGTEMIITKAGRRMFPAMRVKITGLDPHQQYYIAMDIVPVDNKRYRYVYHSS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 KWMVAGNADSPVPPRVYIHPDSLASGDTWMRQVVSFDKLKLTNNELDDQGHIILHSMHKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KWMVAGNADSPVPPRVYIHPDSLASGDTWMRQVVSFDKLKLTNNELDDQGHIILHSMHKY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 QPRVHVIRKDFSSDLSPTKPVPVGDGVKTFNFPETVFTTVTAYQNQQITRLKIDRNPFAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QPRVHVIRKDFSSDLSPTKPVPVGDGVKTFNFPETVFTTVTAYQNQQITRLKIDRNPFAK
250 260 270 280 290 300
310 320 330 340
pF1KE3 GFRDSGRNRTGLEAIMETYAFWRPPVRTLTFEDFTTMQKQQG------------------
:::::::::::::::::::::::::::::::::::::::::.
XP_005 GFRDSGRNRTGLEAIMETYAFWRPPVRTLTFEDFTTMQKQQASKKTSQGYTVNQHSSETD
310 320 330 340 350 360
350 360 370 380
pF1KE3 ---------------GSTGTSPTTSSTGTPSPSASSHLLSPSCSPPTFHLAPNTFNVGCR
:::::::::::::::::::::::::::::::::::::::::::::
XP_005 AIELYERRVWLMERRGSTGTSPTTSSTGTPSPSASSHLLSPSCSPPTFHLAPNTFNVGCR
370 380 390 400 410 420
390 400 410 420 430 440
pF1KE3 ESQLCNLNLSDYPPCARSNMAALQSYPGLSDSGYNRLQSGTTSATQPSETFMPQRTPSLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ESQLCNLNLSDYPPCARSNMAALQSYPGLSDSGYNRLQSGTTSATQPSETFMPQRTPSLI
430 440 450 460 470 480
450 460 470 480 490 500
pF1KE3 SGIPTPPSLPGNSKMEAYGGQLGSFPTSQFQYVMQAGNAASSSSSPHMFGGSHMQQSSYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SGIPTPPSLPGNSKMEAYGGQLGSFPTSQFQYVMQAGNAASSSSSPHMFGGSHMQQSSYN
490 500 510 520 530 540
510 520 530 540 550 560
pF1KE3 AFSLHNPYNLYGYNFPTSPRLAASPEKLSASQSTLLCSSPSNGAFGERQYLPSGMEHSMH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AFSLHNPYNLYGYNFPTSPRLAASPEKLSASQSTLLCSSPSNGAFGERQYLPSGMEHSMH
550 560 570 580 590 600
570 580 590 600
pF1KE3 MISPSPNNQQATNTCDGRQYGAVPGSSSQMSVHMV
:::::::::::::::::::::::::::::::::::
XP_005 MISPSPNNQQATNTCDGRQYGAVPGSSSQMSVHMV
610 620 630
>>XP_011540354 (OMIM: 260660,604127) PREDICTED: T-box tr (320 aa)
initn: 1941 init1: 1773 opt: 1773 Z-score: 1373.9 bits: 263.3 E(85289): 8.7e-70
Smith-Waterman score: 1879; 89.4% identity (89.7% similar) in 320 aa overlap (316-602:1-320)
290 300 310 320 330 340
pF1KE3 QQITRLKIDRNPFAKGFRDSGRNRTGLEAIMETYAFWRPPVRTLTFEDFTTMQKQQG---
::::::::::::::::::::::::::.
XP_011 METYAFWRPPVRTLTFEDFTTMQKQQASKK
10 20 30
350 360 370
pF1KE3 ------------------------------GSTGTSPTTSSTGTPSPSASSHLLSPSCSP
::::::::::::::::::::::::::::::
XP_011 TSQGYTVNQHSSETDAIELYERRVWLMERRGSTGTSPTTSSTGTPSPSASSHLLSPSCSP
40 50 60 70 80 90
380 390 400 410 420 430
pF1KE3 PTFHLAPNTFNVGCRESQLCNLNLSDYPPCARSNMAALQSYPGLSDSGYNRLQSGTTSAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PTFHLAPNTFNVGCRESQLCNLNLSDYPPCARSNMAALQSYPGLSDSGYNRLQSGTTSAT
100 110 120 130 140 150
440 450 460 470 480 490
pF1KE3 QPSETFMPQRTPSLISGIPTPPSLPGNSKMEAYGGQLGSFPTSQFQYVMQAGNAASSSSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QPSETFMPQRTPSLISGIPTPPSLPGNSKMEAYGGQLGSFPTSQFQYVMQAGNAASSSSS
160 170 180 190 200 210
500 510 520 530 540 550
pF1KE3 PHMFGGSHMQQSSYNAFSLHNPYNLYGYNFPTSPRLAASPEKLSASQSTLLCSSPSNGAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PHMFGGSHMQQSSYNAFSLHNPYNLYGYNFPTSPRLAASPEKLSASQSTLLCSSPSNGAF
220 230 240 250 260 270
560 570 580 590 600
pF1KE3 GERQYLPSGMEHSMHMISPSPNNQQATNTCDGRQYGAVPGSSSQMSVHMV
::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GERQYLPSGMEHSMHMISPSPNNQQATNTCDGRQYGAVPGSSSQMSVHMV
280 290 300 310 320
>>NP_001073977 (OMIM: 143100,143400,604613) T-box transc (607 aa)
initn: 1873 init1: 1405 opt: 1557 Z-score: 1204.2 bits: 232.9 E(85289): 2.4e-60
Smith-Waterman score: 1988; 55.2% identity (73.6% similar) in 636 aa overlap (1-602:1-607)
10 20 30 40 50
pF1KE3 MSERRRSA--VALSSRAHAFSVEALIGSNKKRKLRDWEEK-GLDLSMEALSPAG---PLG
:.:.::.. :: .:::::::::::..:...:. ..: : . . :.. .: :
NP_001 MAEKRRGSPCSMLSLKAHAFSVEALIGAEKQQQLQKKRRKLGAEEAAGAVDDGGCSRGGG
10 20 30 40 50 60
60 70 80 90 100
pF1KE3 DTEDAAAHGLE----PHPDSEQSTGSDSEVLTERTS---C--SFSTH-TDLASGAAGP--
: ....: : : : . : . : . :: . : .:. . ::: ...:
NP_001 AGEKGSSEGDEGAALPPPAGATSGPARSGADLERGAAGGCEDGFQQGASPLASPGGSPKG
70 80 90 100 110 120
110 120 130 140 150
pF1KE3 VPA--------AMSSMEEIQVELQCADLWKRFHDIGTEMIITKAGRRMFPAMRVKITGLD
:: . : . .:.:: :.::::::.::::::::::::::::::::::.:::
NP_001 SPARSLARPGTPLPSPQAPRVDLQGAELWKRFHEIGTEMIITKAGRRMFPAMRVKISGLD
130 140 150 160 170 180
160 170 180 190 200 210
pF1KE3 PHQQYYIAMDIVPVDNKRYRYVYHSSKWMVAGNADSPVPPRVYIHPDSLASGDTWMRQVV
:::::::::::::::::::::::::::::::::::::::::::::::: :::.::::::.
NP_001 PHQQYYIAMDIVPVDNKRYRYVYHSSKWMVAGNADSPVPPRVYIHPDSPASGETWMRQVI
190 200 210 220 230 240
220 230 240 250 260 270
pF1KE3 SFDKLKLTNNELDDQGHIILHSMHKYQPRVHVIRKDFSSDLSPTKPVPVGDGVKTFNFPE
:::::::::::::::::::::::::::::::::::: ..:::: :::: :.:::.:.:::
NP_001 SFDKLKLTNNELDDQGHIILHSMHKYQPRVHVIRKDCGDDLSPIKPVPSGEGVKAFSFPE
250 260 270 280 290 300
280 290 300 310 320 330
pF1KE3 TVFTTVTAYQNQQITRLKIDRNPFAKGFRDSGRNRTGLEAIMETYAFWRPPVRTLTFEDF
::::::::::::::::::::::::::::::::::: ::::..:.:::::: .:::::::.
NP_001 TVFTTVTAYQNQQITRLKIDRNPFAKGFRDSGRNRMGLEALVESYAFWRPSLRTLTFEDI
310 320 330 340 350 360
340 350 360 370 380 390
pF1KE3 TTMQKQQGGSTGTSPTTSSTGTPSPSASSHLLS-PSCSPPTFHLAPNTFNVGCRESQLCN
. :: :....: ..::. :.. :::: ::: :.:::.::: ::::.
NP_001 PGIPKQ--GNASSSTLLQGTGNGVPATHPHLLSGSSCSSPAFHLGPNT-------SQLCS
370 380 390 400 410
400 410 420 430 440 450
pF1KE3 LNLSDYPPCARSNMAALQSYPGLSDSGYNRLQSGTTSATQPSETFMPQRTPSLISGIPTP
: .:: ::::... . .:... :::: . : .::: : :::: . :. .
NP_001 LAPADYSACARSGLTLNRYSTSLAET-YNRLTN------QAGETFAPPRTPSYV-GVSSS
420 430 440 450 460
460 470 480 490 500
pF1KE3 PSLPGNSKMEAYGGQLG-SFPTSQFQYVMQAGNAASS------SSSPHMFGGSHMQQSSY
:. : .: :: : .: : . :: .. . . : : . :. .. .:.::
NP_001 TSV--NMSM---GGTDGDTFSCPQTSLSMQISGMSPQLQYIMPSPSSNAFATNQTHQGSY
470 480 490 500 510
510 520 530 540 550 560
pF1KE3 NAFSLHNPYNLYGYNFPTSPRLAASPEKLSASQSTLLCSSPSNGAFGERQYLPSGMEHSM
:.: ::.: :::::: :::.:::::::. .::...: :::: :.. .::.:: .: ..
NP_001 NTFRLHSPCALYGYNFSTSPKLAASPEKIVSSQGSFLGSSPS-GTMTDRQMLPP-VE-GV
520 530 540 550 560 570
570 580 590 600
pF1KE3 HMISPSPNNQQATNTCDGRQYGAVPGSSSQMSVHMV
:..: ..::. :.: :.. ::::.:.:::
NP_001 HLLSS--GGQQS--FFDSRTLGSLTLSSSQVSAHMV
580 590 600
>>XP_016866961 (OMIM: 143100,143400,604613) PREDICTED: T (449 aa)
initn: 1657 init1: 1304 opt: 1452 Z-score: 1125.8 bits: 217.9 E(85289): 5.7e-56
Smith-Waterman score: 1794; 61.5% identity (78.0% similar) in 478 aa overlap (133-602:1-449)
110 120 130 140 150 160
pF1KE3 VPAAMSSMEEIQVELQCADLWKRFHDIGTEMIITKAGRRMFPAMRVKITGLDPHQQYYIA
::::::::::::::::::.:::::::::::
XP_016 MIITKAGRRMFPAMRVKISGLDPHQQYYIA
10 20 30
170 180 190 200 210 220
pF1KE3 MDIVPVDNKRYRYVYHSSKWMVAGNADSPVPPRVYIHPDSLASGDTWMRQVVSFDKLKLT
:::::::::::::::::::::::::::::::::::::::: :::.::::::.::::::::
XP_016 MDIVPVDNKRYRYVYHSSKWMVAGNADSPVPPRVYIHPDSPASGETWMRQVISFDKLKLT
40 50 60 70 80 90
230 240 250 260 270 280
pF1KE3 NNELDDQGHIILHSMHKYQPRVHVIRKDFSSDLSPTKPVPVGDGVKTFNFPETVFTTVTA
:::::::::::::::::::::::::::: ..:::: :::: :.:::.:.:::::::::::
XP_016 NNELDDQGHIILHSMHKYQPRVHVIRKDCGDDLSPIKPVPSGEGVKAFSFPETVFTTVTA
100 110 120 130 140 150
290 300 310 320 330 340
pF1KE3 YQNQQITRLKIDRNPFAKGFRDSGRNRTGLEAIMETYAFWRPPVRTLTFEDFTTMQKQQG
::::::::::::::::::::::::::: ::::..:.:::::: .:::::::. . ::
XP_016 YQNQQITRLKIDRNPFAKGFRDSGRNRMGLEALVESYAFWRPSLRTLTFEDIPGIPKQ--
160 170 180 190 200
350 360 370 380 390 400
pF1KE3 GSTGTSPTTSSTGTPSPSASSHLLS-PSCSPPTFHLAPNTFNVGCRESQLCNLNLSDYPP
:....: ..::. :.. :::: ::: :.:::.::: ::::.: .::
XP_016 GNASSSTLLQGTGNGVPATHPHLLSGSSCSSPAFHLGPNT-------SQLCSLAPADYSA
210 220 230 240 250 260
410 420 430 440 450 460
pF1KE3 CARSNMAALQSYPGLSDSGYNRLQSGTTSATQPSETFMPQRTPSLISGIPTPPSLPGNSK
::::... . .:... :::: . : .::: : :::: . :. . :. : .
XP_016 CARSGLTLNRYSTSLAET-YNRLTN------QAGETFAPPRTPSYV-GVSSSTSV--NMS
270 280 290 300 310
470 480 490 500 510
pF1KE3 MEAYGGQLG-SFPTSQFQYVMQAGNAASS------SSSPHMFGGSHMQQSSYNAFSLHNP
: :: : .: : . :: .. . . : : . :. .. .:.:::.: ::.:
XP_016 M---GGTDGDTFSCPQTSLSMQISGMSPQLQYIMPSPSSNAFATNQTHQGSYNTFRLHSP
320 330 340 350 360
520 530 540 550 560 570
pF1KE3 YNLYGYNFPTSPRLAASPEKLSASQSTLLCSSPSNGAFGERQYLPSGMEHSMHMISPSPN
:::::: :::.:::::::. .::...: :::: :.. .::.:: ...:..: .
XP_016 CALYGYNFSTSPKLAASPEKIVSSQGSFLGSSPS-GTMTDRQMLPP--VEGVHLLSSG--
370 380 390 400 410 420
580 590 600
pF1KE3 NQQATNTCDGRQYGAVPGSSSQMSVHMV
.::. :.: :.. ::::.:.:::
XP_016 GQQSF--FDSRTLGSLTLSSSQVSAHMV
430 440
>>XP_011534550 (OMIM: 143100,143400,604613) PREDICTED: T (377 aa)
initn: 1499 init1: 1384 opt: 1401 Z-score: 1088.0 bits: 210.7 E(85289): 7.3e-54
Smith-Waterman score: 1475; 64.1% identity (77.7% similar) in 382 aa overlap (11-368:2-376)
10 20 30 40 50
pF1KE3 MSERRRSAVALSSRAHAFSVEALIGSNKKRKLRDWEEK-GLDLSMEALSPAG---PLGDT
:: .:::::::::::..:...:. ..: : . . :.. .: :
XP_011 MLSLKAHAFSVEALIGAEKQQQLQKKRRKLGAEEAAGAVDDGGCSRGGGAG
10 20 30 40 50
60 70 80 90 100
pF1KE3 EDAAAHGLE----PHPDSEQSTGSDSEVLTERTS---C--SFSTH-TDLASGAAGP--VP
: ....: : : : . : . : . :: . : .:. . ::: ...: :
XP_011 EKGSSEGDEGAALPPPAGATSGPARSGADLERGAAGGCEDGFQQGASPLASPGGSPKGSP
60 70 80 90 100 110
110 120 130 140 150
pF1KE3 A--------AMSSMEEIQVELQCADLWKRFHDIGTEMIITKAGRRMFPAMRVKITGLDPH
: . : . .:.:: :.::::::.::::::::::::::::::::::.:::::
XP_011 ARSLARPGTPLPSPQAPRVDLQGAELWKRFHEIGTEMIITKAGRRMFPAMRVKISGLDPH
120 130 140 150 160 170
160 170 180 190 200 210
pF1KE3 QQYYIAMDIVPVDNKRYRYVYHSSKWMVAGNADSPVPPRVYIHPDSLASGDTWMRQVVSF
:::::::::::::::::::::::::::::::::::::::::::::: :::.::::::.::
XP_011 QQYYIAMDIVPVDNKRYRYVYHSSKWMVAGNADSPVPPRVYIHPDSPASGETWMRQVISF
180 190 200 210 220 230
220 230 240 250 260 270
pF1KE3 DKLKLTNNELDDQGHIILHSMHKYQPRVHVIRKDFSSDLSPTKPVPVGDGVKTFNFPETV
:::::::::::::::::::::::::::::::::: ..:::: :::: :.:::.:.:::::
XP_011 DKLKLTNNELDDQGHIILHSMHKYQPRVHVIRKDCGDDLSPIKPVPSGEGVKAFSFPETV
240 250 260 270 280 290
280 290 300 310 320 330
pF1KE3 FTTVTAYQNQQITRLKIDRNPFAKGFRDSGRNRTGLEAIMETYAFWRPPVRTLTFEDFTT
::::::::::::::::::::::::::::::::: ::::..:.:::::: .:::::::.
XP_011 FTTVTAYQNQQITRLKIDRNPFAKGFRDSGRNRMGLEALVESYAFWRPSLRTLTFEDIPG
300 310 320 330 340 350
340 350 360 370 380 390
pF1KE3 MQKQQGGSTGTSPTTSSTGTPSPSASSHLLSPSCSPPTFHLAPNTFNVGCRESQLCNLNL
. ::.: :: : .:. : :.:
XP_011 IPKQDGKH---SPQ----GKNAPKMYSGELGPI
360 370
400 410 420 430 440 450
pF1KE3 SDYPPCARSNMAALQSYPGLSDSGYNRLQSGTTSATQPSETFMPQRTPSLISGIPTPPSL
>>XP_006715665 (OMIM: 143100,143400,604613) PREDICTED: T (364 aa)
initn: 1499 init1: 1384 opt: 1396 Z-score: 1084.4 bits: 210.0 E(85289): 1.2e-53
Smith-Waterman score: 1470; 66.1% identity (80.3% similar) in 360 aa overlap (11-346:2-361)
10 20 30 40 50
pF1KE3 MSERRRSAVALSSRAHAFSVEALIGSNKKRKLRDWEEK-GLDLSMEALSPAG---PLGDT
:: .:::::::::::..:...:. ..: : . . :.. .: :
XP_006 MLSLKAHAFSVEALIGAEKQQQLQKKRRKLGAEEAAGAVDDGGCSRGGGAG
10 20 30 40 50
60 70 80 90 100
pF1KE3 EDAAAHGLE----PHPDSEQSTGSDSEVLTERTS---C--SFSTH-TDLASGAAGP--VP
: ....: : : : . : . : . :: . : .:. . ::: ...: :
XP_006 EKGSSEGDEGAALPPPAGATSGPARSGADLERGAAGGCEDGFQQGASPLASPGGSPKGSP
60 70 80 90 100 110
110 120 130 140 150
pF1KE3 A--------AMSSMEEIQVELQCADLWKRFHDIGTEMIITKAGRRMFPAMRVKITGLDPH
: . : . .:.:: :.::::::.::::::::::::::::::::::.:::::
XP_006 ARSLARPGTPLPSPQAPRVDLQGAELWKRFHEIGTEMIITKAGRRMFPAMRVKISGLDPH
120 130 140 150 160 170
160 170 180 190 200 210
pF1KE3 QQYYIAMDIVPVDNKRYRYVYHSSKWMVAGNADSPVPPRVYIHPDSLASGDTWMRQVVSF
:::::::::::::::::::::::::::::::::::::::::::::: :::.::::::.::
XP_006 QQYYIAMDIVPVDNKRYRYVYHSSKWMVAGNADSPVPPRVYIHPDSPASGETWMRQVISF
180 190 200 210 220 230
220 230 240 250 260 270
pF1KE3 DKLKLTNNELDDQGHIILHSMHKYQPRVHVIRKDFSSDLSPTKPVPVGDGVKTFNFPETV
:::::::::::::::::::::::::::::::::: ..:::: :::: :.:::.:.:::::
XP_006 DKLKLTNNELDDQGHIILHSMHKYQPRVHVIRKDCGDDLSPIKPVPSGEGVKAFSFPETV
240 250 260 270 280 290
280 290 300 310 320 330
pF1KE3 FTTVTAYQNQQITRLKIDRNPFAKGFRDSGRNRTGLEAIMETYAFWRPPVRTLTFEDFTT
::::::::::::::::::::::::::::::::: ::::..:.:::::: .:::::::.
XP_006 FTTVTAYQNQQITRLKIDRNPFAKGFRDSGRNRMGLEALVESYAFWRPSLRTLTFEDIPG
300 310 320 330 340 350
340 350 360 370 380 390
pF1KE3 MQKQQGGSTGTSPTTSSTGTPSPSASSHLLSPSCSPPTFHLAPNTFNVGCRESQLCNLNL
. ::. .. :
XP_006 IPKQERATIGWNA
360
>>XP_011534549 (OMIM: 143100,143400,604613) PREDICTED: T (379 aa)
initn: 1493 init1: 1378 opt: 1390 Z-score: 1079.5 bits: 209.1 E(85289): 2.2e-53
Smith-Waterman score: 1464; 66.8% identity (80.6% similar) in 355 aa overlap (11-341:2-356)
10 20 30 40 50
pF1KE3 MSERRRSAVALSSRAHAFSVEALIGSNKKRKLRDWEEK-GLDLSMEALSPAG---PLGDT
:: .:::::::::::..:...:. ..: : . . :.. .: :
XP_011 MLSLKAHAFSVEALIGAEKQQQLQKKRRKLGAEEAAGAVDDGGCSRGGGAG
10 20 30 40 50
60 70 80 90 100
pF1KE3 EDAAAHGLE----PHPDSEQSTGSDSEVLTERTS---C--SFSTH-TDLASGAAGP--VP
: ....: : : : . : . : . :: . : .:. . ::: ...: :
XP_011 EKGSSEGDEGAALPPPAGATSGPARSGADLERGAAGGCEDGFQQGASPLASPGGSPKGSP
60 70 80 90 100 110
110 120 130 140 150
pF1KE3 A--------AMSSMEEIQVELQCADLWKRFHDIGTEMIITKAGRRMFPAMRVKITGLDPH
: . : . .:.:: :.::::::.::::::::::::::::::::::.:::::
XP_011 ARSLARPGTPLPSPQAPRVDLQGAELWKRFHEIGTEMIITKAGRRMFPAMRVKISGLDPH
120 130 140 150 160 170
160 170 180 190 200 210
pF1KE3 QQYYIAMDIVPVDNKRYRYVYHSSKWMVAGNADSPVPPRVYIHPDSLASGDTWMRQVVSF
:::::::::::::::::::::::::::::::::::::::::::::: :::.::::::.::
XP_011 QQYYIAMDIVPVDNKRYRYVYHSSKWMVAGNADSPVPPRVYIHPDSPASGETWMRQVISF
180 190 200 210 220 230
220 230 240 250 260 270
pF1KE3 DKLKLTNNELDDQGHIILHSMHKYQPRVHVIRKDFSSDLSPTKPVPVGDGVKTFNFPETV
:::::::::::::::::::::::::::::::::: ..:::: :::: :.:::.:.:::::
XP_011 DKLKLTNNELDDQGHIILHSMHKYQPRVHVIRKDCGDDLSPIKPVPSGEGVKAFSFPETV
240 250 260 270 280 290
280 290 300 310 320 330
pF1KE3 FTTVTAYQNQQITRLKIDRNPFAKGFRDSGRNRTGLEAIMETYAFWRPPVRTLTFEDFTT
::::::::::::::::::::::::::::::::: ::::..:.:::::: .:::::::.
XP_011 FTTVTAYQNQQITRLKIDRNPFAKGFRDSGRNRMGLEALVESYAFWRPSLRTLTFEDIPG
300 310 320 330 340 350
340 350 360 370 380 390
pF1KE3 MQKQQGGSTGTSPTTSSTGTPSPSASSHLLSPSCSPPTFHLAPNTFNVGCRESQLCNLNL
. ::.
XP_011 IPKQEYRDLKTDYIFPERDNLVSRETKL
360 370
>>XP_011534551 (OMIM: 143100,143400,604613) PREDICTED: T (372 aa)
initn: 1528 init1: 1384 opt: 1388 Z-score: 1078.1 bits: 208.8 E(85289): 2.6e-53
Smith-Waterman score: 1462; 66.9% identity (80.5% similar) in 354 aa overlap (11-340:2-355)
10 20 30 40 50
pF1KE3 MSERRRSAVALSSRAHAFSVEALIGSNKKRKLRDWEEK-GLDLSMEALSPAG---PLGDT
:: .:::::::::::..:...:. ..: : . . :.. .: :
XP_011 MLSLKAHAFSVEALIGAEKQQQLQKKRRKLGAEEAAGAVDDGGCSRGGGAG
10 20 30 40 50
60 70 80 90 100
pF1KE3 EDAAAHGLE----PHPDSEQSTGSDSEVLTERTS---C--SFSTH-TDLASGAAGP--VP
: ....: : : : . : . : . :: . : .:. . ::: ...: :
XP_011 EKGSSEGDEGAALPPPAGATSGPARSGADLERGAAGGCEDGFQQGASPLASPGGSPKGSP
60 70 80 90 100 110
110 120 130 140 150
pF1KE3 A--------AMSSMEEIQVELQCADLWKRFHDIGTEMIITKAGRRMFPAMRVKITGLDPH
: . : . .:.:: :.::::::.::::::::::::::::::::::.:::::
XP_011 ARSLARPGTPLPSPQAPRVDLQGAELWKRFHEIGTEMIITKAGRRMFPAMRVKISGLDPH
120 130 140 150 160 170
160 170 180 190 200 210
pF1KE3 QQYYIAMDIVPVDNKRYRYVYHSSKWMVAGNADSPVPPRVYIHPDSLASGDTWMRQVVSF
:::::::::::::::::::::::::::::::::::::::::::::: :::.::::::.::
XP_011 QQYYIAMDIVPVDNKRYRYVYHSSKWMVAGNADSPVPPRVYIHPDSPASGETWMRQVISF
180 190 200 210 220 230
220 230 240 250 260 270
pF1KE3 DKLKLTNNELDDQGHIILHSMHKYQPRVHVIRKDFSSDLSPTKPVPVGDGVKTFNFPETV
:::::::::::::::::::::::::::::::::: ..:::: :::: :.:::.:.:::::
XP_011 DKLKLTNNELDDQGHIILHSMHKYQPRVHVIRKDCGDDLSPIKPVPSGEGVKAFSFPETV
240 250 260 270 280 290
280 290 300 310 320 330
pF1KE3 FTTVTAYQNQQITRLKIDRNPFAKGFRDSGRNRTGLEAIMETYAFWRPPVRTLTFEDFTT
::::::::::::::::::::::::::::::::: ::::..:.:::::: .:::::::.
XP_011 FTTVTAYQNQQITRLKIDRNPFAKGFRDSGRNRMGLEALVESYAFWRPSLRTLTFEDIPG
300 310 320 330 340 350
340 350 360 370 380 390
pF1KE3 MQKQQGGSTGTSPTTSSTGTPSPSASSHLLSPSCSPPTFHLAPNTFNVGCRESQLCNLNL
. ::
XP_011 IPKQGCQRIQALQSQLRCAEC
360 370
602 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 04:42:09 2016 done: Sun Nov 6 04:42:10 2016
Total Scan time: 9.670 Total Display time: 0.090
Function used was FASTA [36.3.4 Apr, 2011]