Result of FASTA (omim) for
pFN21AE3363
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3363, 1070 aa
1>>>pF1KE3363 1070 - 1070 aa - 1070 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 11.0029+/-0.000654; mu= -3.7446+/- 0.039
mean_var=784.0344+/-186.022, 0's: 0 Z-trim(116.9): 971 B-trim: 0 in 0/59
Lambda= 0.045804
statistics sampled from 27347 (28476) to 27347 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.668), E-opt: 0.2 (0.334), width: 16
Scan time: 13.380
The best scores are: opt bits E(85289)
NP_002812 (OMIM: 601890) inactive tyrosine-protein (1070) 7288 499.3 4.8e-140
NP_001257327 (OMIM: 601890) inactive tyrosine-prot (1078) 7121 488.3 1e-136
NP_690621 (OMIM: 601890) inactive tyrosine-protein (1014) 4304 302.1 1.1e-80
NP_690620 (OMIM: 601890) inactive tyrosine-protein ( 940) 3595 255.2 1.3e-66
XP_011513068 (OMIM: 601890) PREDICTED: inactive ty ( 948) 3595 255.2 1.3e-66
NP_690619 (OMIM: 601890) inactive tyrosine-protein (1030) 3588 254.8 1.9e-66
XP_011513067 (OMIM: 601890) PREDICTED: inactive ty (1038) 3588 254.8 1.9e-66
NP_001007793 (OMIM: 155240,191315,256800) high aff ( 760) 730 65.7 1.1e-09
NP_001012331 (OMIM: 155240,191315,256800) high aff ( 790) 730 65.7 1.2e-09
NP_002520 (OMIM: 155240,191315,256800) high affini ( 796) 725 65.4 1.5e-09
NP_996844 (OMIM: 151520) leukocyte tyrosine kinase ( 803) 713 64.6 2.6e-09
NP_002335 (OMIM: 151520) leukocyte tyrosine kinase ( 864) 713 64.7 2.7e-09
XP_016870223 (OMIM: 208150,601296,616325) PREDICTE ( 791) 712 64.6 2.7e-09
NP_004295 (OMIM: 105590,613014) ALK tyrosine kinas (1620) 715 65.3 3.3e-09
NP_001159752 (OMIM: 208150,601296,616325) muscle, ( 783) 706 64.1 3.5e-09
XP_011534355 (OMIM: 165020) PREDICTED: proto-oncog (2299) 713 65.4 4.4e-09
XP_016866662 (OMIM: 165020) PREDICTED: proto-oncog (2333) 713 65.4 4.4e-09
XP_016866661 (OMIM: 165020) PREDICTED: proto-oncog (2334) 713 65.4 4.4e-09
XP_006715611 (OMIM: 165020) PREDICTED: proto-oncog (2342) 713 65.4 4.4e-09
XP_011534354 (OMIM: 165020) PREDICTED: proto-oncog (2343) 713 65.4 4.4e-09
NP_002935 (OMIM: 165020) proto-oncogene tyrosine-p (2347) 713 65.4 4.4e-09
XP_011534353 (OMIM: 165020) PREDICTED: proto-oncog (2348) 713 65.4 4.4e-09
XP_011534352 (OMIM: 165020) PREDICTED: proto-oncog (2356) 713 65.4 4.4e-09
XP_011534351 (OMIM: 165020) PREDICTED: proto-oncog (2357) 713 65.4 4.4e-09
XP_011519859 (OMIM: 151520) PREDICTED: leukocyte t ( 824) 694 63.4 6.2e-09
XP_016877671 (OMIM: 151520) PREDICTED: leukocyte t ( 837) 694 63.4 6.3e-09
XP_011519858 (OMIM: 151520) PREDICTED: leukocyte t ( 880) 694 63.4 6.4e-09
XP_016877670 (OMIM: 151520) PREDICTED: leukocyte t ( 885) 694 63.4 6.4e-09
NP_001018074 (OMIM: 600456,613886) BDNF/NT-3 growt ( 822) 688 63.0 8.2e-09
XP_016870243 (OMIM: 600456,613886) PREDICTED: BDNF ( 822) 688 63.0 8.2e-09
XP_016870242 (OMIM: 600456,613886) PREDICTED: BDNF ( 822) 688 63.0 8.2e-09
XP_011517020 (OMIM: 600456,613886) PREDICTED: BDNF ( 822) 688 63.0 8.2e-09
XP_016870241 (OMIM: 600456,613886) PREDICTED: BDNF ( 822) 688 63.0 8.2e-09
XP_016877741 (OMIM: 191316) PREDICTED: NT-3 growth ( 448) 680 62.0 8.7e-09
XP_016877740 (OMIM: 191316) PREDICTED: NT-3 growth ( 456) 680 62.0 8.8e-09
XP_016877735 (OMIM: 191316) PREDICTED: NT-3 growth ( 727) 680 62.4 1.1e-08
XP_016877734 (OMIM: 191316) PREDICTED: NT-3 growth ( 727) 680 62.4 1.1e-08
XP_016877733 (OMIM: 191316) PREDICTED: NT-3 growth ( 727) 680 62.4 1.1e-08
XP_016877732 (OMIM: 191316) PREDICTED: NT-3 growth ( 727) 680 62.4 1.1e-08
XP_016877730 (OMIM: 191316) PREDICTED: NT-3 growth ( 763) 680 62.4 1.1e-08
XP_006720607 (OMIM: 191316) PREDICTED: NT-3 growth ( 817) 680 62.5 1.2e-08
NP_001230030 (OMIM: 191316) NT-3 growth factor rec ( 817) 680 62.5 1.2e-08
XP_006720606 (OMIM: 191316) PREDICTED: NT-3 growth ( 825) 680 62.5 1.2e-08
XP_016877729 (OMIM: 191316) PREDICTED: NT-3 growth ( 825) 680 62.5 1.2e-08
NP_002521 (OMIM: 191316) NT-3 growth factor recept ( 825) 680 62.5 1.2e-08
XP_005252061 (OMIM: 600456,613886) PREDICTED: BDNF ( 838) 679 62.4 1.2e-08
XP_005252060 (OMIM: 600456,613886) PREDICTED: BDNF ( 838) 679 62.4 1.2e-08
NP_006171 (OMIM: 600456,613886) BDNF/NT-3 growth f ( 838) 679 62.4 1.2e-08
XP_016870240 (OMIM: 600456,613886) PREDICTED: BDNF ( 838) 679 62.4 1.2e-08
XP_005252058 (OMIM: 600456,613886) PREDICTED: BDNF ( 838) 679 62.4 1.2e-08
>>NP_002812 (OMIM: 601890) inactive tyrosine-protein kin (1070 aa)
initn: 7288 init1: 7288 opt: 7288 Z-score: 2635.3 bits: 499.3 E(85289): 4.8e-140
Smith-Waterman score: 7288; 100.0% identity (100.0% similar) in 1070 aa overlap (1-1070:1-1070)
10 20 30 40 50 60
pF1KE3 MGAARGSPARPRRLPLLSVLLLPLLGGTQTAIVFIKQPSSQDALQGRRALLRCEVEAPGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MGAARGSPARPRRLPLLSVLLLPLLGGTQTAIVFIKQPSSQDALQGRRALLRCEVEAPGP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 VHVYWLLDGAPVQDTERRFAQGSSLSFAAVDRLQDSGTFQCVARDDVTGEEARSANASFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 VHVYWLLDGAPVQDTERRFAQGSSLSFAAVDRLQDSGTFQCVARDDVTGEEARSANASFN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 IKWIEAGPVVLKHPASEAEIQPQTQVTLRCHIDGHPRPTYQWFRDGTPLSDGQSNHTVSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 IKWIEAGPVVLKHPASEAEIQPQTQVTLRCHIDGHPRPTYQWFRDGTPLSDGQSNHTVSS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 KERNLTLRPAGPEHSGLYSCCAHSAFGQACSSQNFTLSIADESFARVVLAPQDVVVARYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 KERNLTLRPAGPEHSGLYSCCAHSAFGQACSSQNFTLSIADESFARVVLAPQDVVVARYE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 EAMFHCQFSAQPPPSLQWLFEDETPITNRSRPPHLRRATVFANGSLLLTQVRPRNAGIYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 EAMFHCQFSAQPPPSLQWLFEDETPITNRSRPPHLRRATVFANGSLLLTQVRPRNAGIYR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 CIGQGQRGPPIILEATLHLAEIEDMPLFEPRVFTAGSEERVTCLPPKGLPEPSVWWEHAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 CIGQGQRGPPIILEATLHLAEIEDMPLFEPRVFTAGSEERVTCLPPKGLPEPSVWWEHAG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 VRLPTHGRVYQKGHELVLANIAESDAGVYTCHAANLAGQRRQDVNITVATVPSWLKKPQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 VRLPTHGRVYQKGHELVLANIAESDAGVYTCHAANLAGQRRQDVNITVATVPSWLKKPQD
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 SQLEEGKPGYLDCLTQATPKPTVVWYRNQMLISEDSRFEVFKNGTLRINSVEVYDGTWYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 SQLEEGKPGYLDCLTQATPKPTVVWYRNQMLISEDSRFEVFKNGTLRINSVEVYDGTWYR
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 CMSSTPAGSIEAQARVQVLEKLKFTPPPQPQQCMEFDKEATVPCSATGREKPTIKWERAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 CMSSTPAGSIEAQARVQVLEKLKFTPPPQPQQCMEFDKEATVPCSATGREKPTIKWERAD
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 GSSLPEWVTDNAGTLHFARVTRDDAGNYTCIASNGPQGQIRAHVQLTVAVFITFKVEPER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 GSSLPEWVTDNAGTLHFARVTRDDAGNYTCIASNGPQGQIRAHVQLTVAVFITFKVEPER
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 TTVYQGHTALLQCEAQGDPKPLIQWKGKDRILDPTKLGPRMHIFQNGSLVIHDVAPEDSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 TTVYQGHTALLQCEAQGDPKPLIQWKGKDRILDPTKLGPRMHIFQNGSLVIHDVAPEDSG
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 RYTCIAGNSCNIKHTEAPLYVVDKPVPEESEGPGSPPPYKMIQTIGLSVGAAVAYIIAVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 RYTCIAGNSCNIKHTEAPLYVVDKPVPEESEGPGSPPPYKMIQTIGLSVGAAVAYIIAVL
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 GLMFYCKKRCKAKRLQKQPEGEEPEMECLNGGPLQNGQPSAEIQEEVALTSLGSGPAATN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 GLMFYCKKRCKAKRLQKQPEGEEPEMECLNGGPLQNGQPSAEIQEEVALTSLGSGPAATN
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE3 KRHSTSDKMHFPRSSLQPITTLGKSEFGEVFLAKAQGLEEGVAETLVLVKSLQSKDEQQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 KRHSTSDKMHFPRSSLQPITTLGKSEFGEVFLAKAQGLEEGVAETLVLVKSLQSKDEQQQ
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE3 LDFRRELEMFGKLNHANVVRLLGLCREAEPHYMVLEYVDLGDLKQFLRISKSKDEKLKSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 LDFRRELEMFGKLNHANVVRLLGLCREAEPHYMVLEYVDLGDLKQFLRISKSKDEKLKSQ
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE3 PLSTKQKVALCTQVALGMEHLSNNRFVHKDLAARNCLVSAQRQVKVSALGLSKDVYNSEY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 PLSTKQKVALCTQVALGMEHLSNNRFVHKDLAARNCLVSAQRQVKVSALGLSKDVYNSEY
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE3 YHFRQAWVPLRWMSPEAILEGDFSTKSDVWAFGVLMWEVFTHGEMPHGGQADDEVLADLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 YHFRQAWVPLRWMSPEAILEGDFSTKSDVWAFGVLMWEVFTHGEMPHGGQADDEVLADLQ
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070
pF1KE3 AGKARLPQPEGCPSKLYRLMQRCWALSPKDRPSFSEIASALGDSTVDSKP
::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 AGKARLPQPEGCPSKLYRLMQRCWALSPKDRPSFSEIASALGDSTVDSKP
1030 1040 1050 1060 1070
>>NP_001257327 (OMIM: 601890) inactive tyrosine-protein (1078 aa)
initn: 7119 init1: 7119 opt: 7121 Z-score: 2575.6 bits: 488.3 E(85289): 1e-136
Smith-Waterman score: 7121; 98.4% identity (98.9% similar) in 1065 aa overlap (6-1070:17-1078)
10 20 30 40
pF1KE3 MGAARGSPARPRRLPLLSVLLLPLLGGTQTAIVFIKQPSSQDALQGRRA
:: . ...: . : :::::::::::::::::::::::
NP_001 MGSFLSGEKRPSAPTVGSAMEKKEFPTPPGRVGP---GTQTAIVFIKQPSSQDALQGRRA
10 20 30 40 50
50 60 70 80 90 100
pF1KE3 LLRCEVEAPGPVHVYWLLDGAPVQDTERRFAQGSSLSFAAVDRLQDSGTFQCVARDDVTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLRCEVEAPGPVHVYWLLDGAPVQDTERRFAQGSSLSFAAVDRLQDSGTFQCVARDDVTG
60 70 80 90 100 110
110 120 130 140 150 160
pF1KE3 EEARSANASFNIKWIEAGPVVLKHPASEAEIQPQTQVTLRCHIDGHPRPTYQWFRDGTPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEARSANASFNIKWIEAGPVVLKHPASEAEIQPQTQVTLRCHIDGHPRPTYQWFRDGTPL
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE3 SDGQSNHTVSSKERNLTLRPAGPEHSGLYSCCAHSAFGQACSSQNFTLSIADESFARVVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SDGQSNHTVSSKERNLTLRPAGPEHSGLYSCCAHSAFGQACSSQNFTLSIADESFARVVL
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE3 APQDVVVARYEEAMFHCQFSAQPPPSLQWLFEDETPITNRSRPPHLRRATVFANGSLLLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 APQDVVVARYEEAMFHCQFSAQPPPSLQWLFEDETPITNRSRPPHLRRATVFANGSLLLT
240 250 260 270 280 290
290 300 310 320 330 340
pF1KE3 QVRPRNAGIYRCIGQGQRGPPIILEATLHLAEIEDMPLFEPRVFTAGSEERVTCLPPKGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QVRPRNAGIYRCIGQGQRGPPIILEATLHLAEIEDMPLFEPRVFTAGSEERVTCLPPKGL
300 310 320 330 340 350
350 360 370 380 390 400
pF1KE3 PEPSVWWEHAGVRLPTHGRVYQKGHELVLANIAESDAGVYTCHAANLAGQRRQDVNITVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PEPSVWWEHAGVRLPTHGRVYQKGHELVLANIAESDAGVYTCHAANLAGQRRQDVNITVA
360 370 380 390 400 410
410 420 430 440 450 460
pF1KE3 TVPSWLKKPQDSQLEEGKPGYLDCLTQATPKPTVVWYRNQMLISEDSRFEVFKNGTLRIN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TVPSWLKKPQDSQLEEGKPGYLDCLTQATPKPTVVWYRNQMLISEDSRFEVFKNGTLRIN
420 430 440 450 460 470
470 480 490 500 510 520
pF1KE3 SVEVYDGTWYRCMSSTPAGSIEAQARVQVLEKLKFTPPPQPQQCMEFDKEATVPCSATGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SVEVYDGTWYRCMSSTPAGSIEAQARVQVLEKLKFTPPPQPQQCMEFDKEATVPCSATGR
480 490 500 510 520 530
530 540 550 560 570 580
pF1KE3 EKPTIKWERADGSSLPEWVTDNAGTLHFARVTRDDAGNYTCIASNGPQGQIRAHVQLTVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKPTIKWERADGSSLPEWVTDNAGTLHFARVTRDDAGNYTCIASNGPQGQIRAHVQLTVA
540 550 560 570 580 590
590 600 610 620 630 640
pF1KE3 VFITFKVEPERTTVYQGHTALLQCEAQGDPKPLIQWKGKDRILDPTKLGPRMHIFQNGSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VFITFKVEPERTTVYQGHTALLQCEAQGDPKPLIQWKGKDRILDPTKLGPRMHIFQNGSL
600 610 620 630 640 650
650 660 670 680 690 700
pF1KE3 VIHDVAPEDSGRYTCIAGNSCNIKHTEAPLYVVDKPVPEESEGPGSPPPYKMIQTIGLSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VIHDVAPEDSGRYTCIAGNSCNIKHTEAPLYVVDKPVPEESEGPGSPPPYKMIQTIGLSV
660 670 680 690 700 710
710 720 730 740 750 760
pF1KE3 GAAVAYIIAVLGLMFYCKKRCKAKRLQKQPEGEEPEMECLNGGPLQNGQPSAEIQEEVAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GAAVAYIIAVLGLMFYCKKRCKAKRLQKQPEGEEPEMECLNGGPLQNGQPSAEIQEEVAL
720 730 740 750 760 770
770 780 790 800 810 820
pF1KE3 TSLGSGPAATNKRHSTSDKMHFPRSSLQPITTLGKSEFGEVFLAKAQGLEEGVAETLVLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TSLGSGPAATNKRHSTSDKMHFPRSSLQPITTLGKSEFGEVFLAKAQGLEEGVAETLVLV
780 790 800 810 820 830
830 840 850 860 870 880
pF1KE3 KSLQSKDEQQQLDFRRELEMFGKLNHANVVRLLGLCREAEPHYMVLEYVDLGDLKQFLRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KSLQSKDEQQQLDFRRELEMFGKLNHANVVRLLGLCREAEPHYMVLEYVDLGDLKQFLRI
840 850 860 870 880 890
890 900 910 920 930 940
pF1KE3 SKSKDEKLKSQPLSTKQKVALCTQVALGMEHLSNNRFVHKDLAARNCLVSAQRQVKVSAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SKSKDEKLKSQPLSTKQKVALCTQVALGMEHLSNNRFVHKDLAARNCLVSAQRQVKVSAL
900 910 920 930 940 950
950 960 970 980 990 1000
pF1KE3 GLSKDVYNSEYYHFRQAWVPLRWMSPEAILEGDFSTKSDVWAFGVLMWEVFTHGEMPHGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GLSKDVYNSEYYHFRQAWVPLRWMSPEAILEGDFSTKSDVWAFGVLMWEVFTHGEMPHGG
960 970 980 990 1000 1010
1010 1020 1030 1040 1050 1060
pF1KE3 QADDEVLADLQAGKARLPQPEGCPSKLYRLMQRCWALSPKDRPSFSEIASALGDSTVDSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QADDEVLADLQAGKARLPQPEGCPSKLYRLMQRCWALSPKDRPSFSEIASALGDSTVDSK
1020 1030 1040 1050 1060 1070
1070
pF1KE3 P
:
NP_001 P
>>NP_690621 (OMIM: 601890) inactive tyrosine-protein kin (1014 aa)
initn: 4302 init1: 4302 opt: 4304 Z-score: 1569.8 bits: 302.1 E(85289): 1.1e-80
Smith-Waterman score: 6778; 94.8% identity (94.8% similar) in 1070 aa overlap (1-1070:1-1014)
10 20 30 40 50 60
pF1KE3 MGAARGSPARPRRLPLLSVLLLPLLGGTQTAIVFIKQPSSQDALQGRRALLRCEVEAPGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 MGAARGSPARPRRLPLLSVLLLPLLGGTQTAIVFIKQPSSQDALQGRRALLRCEVEAPGP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 VHVYWLLDGAPVQDTERRFAQGSSLSFAAVDRLQDSGTFQCVARDDVTGEEARSANASFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 VHVYWLLDGAPVQDTERRFAQGSSLSFAAVDRLQDSGTFQCVARDDVTGEEARSANASFN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 IKWIEAGPVVLKHPASEAEIQPQTQVTLRCHIDGHPRPTYQWFRDGTPLSDGQSNHTVSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 IKWIEAGPVVLKHPASEAEIQPQTQVTLRCHIDGHPRPTYQWFRDGTPLSDGQSNHTVSS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 KERNLTLRPAGPEHSGLYSCCAHSAFGQACSSQNFTLSIADESFARVVLAPQDVVVARYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 KERNLTLRPAGPEHSGLYSCCAHSAFGQACSSQNFTLSIADESFARVVLAPQDVVVARYE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 EAMFHCQFSAQPPPSLQWLFEDETPITNRSRPPHLRRATVFANGSLLLTQVRPRNAGIYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 EAMFHCQFSAQPPPSLQWLFEDETPITNRSRPPHLRRATVFANGSLLLTQVRPRNAGIYR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 CIGQGQRGPPIILEATLHLAEIEDMPLFEPRVFTAGSEERVTCLPPKGLPEPSVWWEHAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 CIGQGQRGPPIILEATLHLAEIEDMPLFEPRVFTAGSEERVTCLPPKGLPEPSVWWEHAG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 VRLPTHGRVYQKGHELVLANIAESDAGVYTCHAANLAGQRRQDVNITVATVPSWLKKPQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 VRLPTHGRVYQKGHELVLANIAESDAGVYTCHAANLAGQRRQDVNITVATVPSWLKKPQD
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 SQLEEGKPGYLDCLTQATPKPTVVWYRNQMLISEDSRFEVFKNGTLRINSVEVYDGTWYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 SQLEEGKPGYLDCLTQATPKPTVVWYRNQMLISEDSRFEVFKNGTLRINSVEVYDGTWYR
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 CMSSTPAGSIEAQARVQVLEKLKFTPPPQPQQCMEFDKEATVPCSATGREKPTIKWERAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 CMSSTPAGSIEAQARVQVLEKLKFTPPPQPQQCMEFDKEATVPCSATGREKPTIKWERAD
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 GSSLPEWVTDNAGTLHFARVTRDDAGNYTCIASNGPQGQIRAHVQLTVAVFITFKVEPER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 GSSLPEWVTDNAGTLHFARVTRDDAGNYTCIASNGPQGQIRAHVQLTVAVFITFKVEPER
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 TTVYQGHTALLQCEAQGDPKPLIQWKGKDRILDPTKLGPRMHIFQNGSLVIHDVAPEDSG
::::::::::::::::::::::::::
NP_690 TTVYQGHTALLQCEAQGDPKPLIQWK----------------------------------
610 620
670 680 690 700 710 720
pF1KE3 RYTCIAGNSCNIKHTEAPLYVVDKPVPEESEGPGSPPPYKMIQTIGLSVGAAVAYIIAVL
::::::::::::::::::::::::::::::::::::::
NP_690 ----------------------DKPVPEESEGPGSPPPYKMIQTIGLSVGAAVAYIIAVL
630 640 650 660
730 740 750 760 770 780
pF1KE3 GLMFYCKKRCKAKRLQKQPEGEEPEMECLNGGPLQNGQPSAEIQEEVALTSLGSGPAATN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 GLMFYCKKRCKAKRLQKQPEGEEPEMECLNGGPLQNGQPSAEIQEEVALTSLGSGPAATN
670 680 690 700 710 720
790 800 810 820 830 840
pF1KE3 KRHSTSDKMHFPRSSLQPITTLGKSEFGEVFLAKAQGLEEGVAETLVLVKSLQSKDEQQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 KRHSTSDKMHFPRSSLQPITTLGKSEFGEVFLAKAQGLEEGVAETLVLVKSLQSKDEQQQ
730 740 750 760 770 780
850 860 870 880 890 900
pF1KE3 LDFRRELEMFGKLNHANVVRLLGLCREAEPHYMVLEYVDLGDLKQFLRISKSKDEKLKSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 LDFRRELEMFGKLNHANVVRLLGLCREAEPHYMVLEYVDLGDLKQFLRISKSKDEKLKSQ
790 800 810 820 830 840
910 920 930 940 950 960
pF1KE3 PLSTKQKVALCTQVALGMEHLSNNRFVHKDLAARNCLVSAQRQVKVSALGLSKDVYNSEY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 PLSTKQKVALCTQVALGMEHLSNNRFVHKDLAARNCLVSAQRQVKVSALGLSKDVYNSEY
850 860 870 880 890 900
970 980 990 1000 1010 1020
pF1KE3 YHFRQAWVPLRWMSPEAILEGDFSTKSDVWAFGVLMWEVFTHGEMPHGGQADDEVLADLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 YHFRQAWVPLRWMSPEAILEGDFSTKSDVWAFGVLMWEVFTHGEMPHGGQADDEVLADLQ
910 920 930 940 950 960
1030 1040 1050 1060 1070
pF1KE3 AGKARLPQPEGCPSKLYRLMQRCWALSPKDRPSFSEIASALGDSTVDSKP
::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 AGKARLPQPEGCPSKLYRLMQRCWALSPKDRPSFSEIASALGDSTVDSKP
970 980 990 1000 1010
>>NP_690620 (OMIM: 601890) inactive tyrosine-protein kin (940 aa)
initn: 3587 init1: 3587 opt: 3595 Z-score: 1316.9 bits: 255.2 E(85289): 1.3e-66
Smith-Waterman score: 6108; 87.8% identity (87.9% similar) in 1070 aa overlap (1-1070:1-940)
10 20 30 40 50 60
pF1KE3 MGAARGSPARPRRLPLLSVLLLPLLGGTQTAIVFIKQPSSQDALQGRRALLRCEVEAPGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 MGAARGSPARPRRLPLLSVLLLPLLGGTQTAIVFIKQPSSQDALQGRRALLRCEVEAPGP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 VHVYWLLDGAPVQDTERRFAQGSSLSFAAVDRLQDSGTFQCVARDDVTGEEARSANASFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 VHVYWLLDGAPVQDTERRFAQGSSLSFAAVDRLQDSGTFQCVARDDVTGEEARSANASFN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 IKWIEAGPVVLKHPASEAEIQPQTQVTLRCHIDGHPRPTYQWFRDGTPLSDGQSNHTVSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 IKWIEAGPVVLKHPASEAEIQPQTQVTLRCHIDGHPRPTYQWFRDGTPLSDGQSNHTVSS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 KERNLTLRPAGPEHSGLYSCCAHSAFGQACSSQNFTLSIADESFARVVLAPQDVVVARYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 KERNLTLRPAGPEHSGLYSCCAHSAFGQACSSQNFTLSIADESFARVVLAPQDVVVARYE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 EAMFHCQFSAQPPPSLQWLFEDETPITNRSRPPHLRRATVFANGSLLLTQVRPRNAGIYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 EAMFHCQFSAQPPPSLQWLFEDETPITNRSRPPHLRRATVFANGSLLLTQVRPRNAGIYR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 CIGQGQRGPPIILEATLHLAEIEDMPLFEPRVFTAGSEERVTCLPPKGLPEPSVWWEHAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 CIGQGQRGPPIILEATLHLAEIEDMPLFEPRVFTAGSEERVTCLPPKGLPEPSVWWEHAG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 VRLPTHGRVYQKGHELVLANIAESDAGVYTCHAANLAGQRRQDVNITVATVPSWLKKPQD
:::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 VRLPTHGRVYQKGHELVLANIAESDAGVYTCHAANLAGQRRQDVNITVA-----------
370 380 390 400
430 440 450 460 470 480
pF1KE3 SQLEEGKPGYLDCLTQATPKPTVVWYRNQMLISEDSRFEVFKNGTLRINSVEVYDGTWYR
NP_690 ------------------------------------------------------------
490 500 510 520 530 540
pF1KE3 CMSSTPAGSIEAQARVQVLEKLKFTPPPQPQQCMEFDKEATVPCSATGREKPTIKWERAD
.
NP_690 -----------------------------------------------------------N
410
550 560 570 580 590 600
pF1KE3 GSSLPEWVTDNAGTLHFARVTRDDAGNYTCIASNGPQGQIRAHVQLTVAVFITFKVEPER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 GSSLPEWVTDNAGTLHFARVTRDDAGNYTCIASNGPQGQIRAHVQLTVAVFITFKVEPER
420 430 440 450 460 470
610 620 630 640 650 660
pF1KE3 TTVYQGHTALLQCEAQGDPKPLIQWKGKDRILDPTKLGPRMHIFQNGSLVIHDVAPEDSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 TTVYQGHTALLQCEAQGDPKPLIQWKGKDRILDPTKLGPRMHIFQNGSLVIHDVAPEDSG
480 490 500 510 520 530
670 680 690 700 710 720
pF1KE3 RYTCIAGNSCNIKHTEAPLYVVDKPVPEESEGPGSPPPYKMIQTIGLSVGAAVAYIIAVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 RYTCIAGNSCNIKHTEAPLYVVDKPVPEESEGPGSPPPYKMIQTIGLSVGAAVAYIIAVL
540 550 560 570 580 590
730 740 750 760 770 780
pF1KE3 GLMFYCKKRCKAKRLQKQPEGEEPEMECLNGGPLQNGQPSAEIQEEVALTSLGSGPAATN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 GLMFYCKKRCKAKRLQKQPEGEEPEMECLNGGPLQNGQPSAEIQEEVALTSLGSGPAATN
600 610 620 630 640 650
790 800 810 820 830 840
pF1KE3 KRHSTSDKMHFPRSSLQPITTLGKSEFGEVFLAKAQGLEEGVAETLVLVKSLQSKDEQQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 KRHSTSDKMHFPRSSLQPITTLGKSEFGEVFLAKAQGLEEGVAETLVLVKSLQSKDEQQQ
660 670 680 690 700 710
850 860 870 880 890 900
pF1KE3 LDFRRELEMFGKLNHANVVRLLGLCREAEPHYMVLEYVDLGDLKQFLRISKSKDEKLKSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 LDFRRELEMFGKLNHANVVRLLGLCREAEPHYMVLEYVDLGDLKQFLRISKSKDEKLKSQ
720 730 740 750 760 770
910 920 930 940 950 960
pF1KE3 PLSTKQKVALCTQVALGMEHLSNNRFVHKDLAARNCLVSAQRQVKVSALGLSKDVYNSEY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 PLSTKQKVALCTQVALGMEHLSNNRFVHKDLAARNCLVSAQRQVKVSALGLSKDVYNSEY
780 790 800 810 820 830
970 980 990 1000 1010 1020
pF1KE3 YHFRQAWVPLRWMSPEAILEGDFSTKSDVWAFGVLMWEVFTHGEMPHGGQADDEVLADLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 YHFRQAWVPLRWMSPEAILEGDFSTKSDVWAFGVLMWEVFTHGEMPHGGQADDEVLADLQ
840 850 860 870 880 890
1030 1040 1050 1060 1070
pF1KE3 AGKARLPQPEGCPSKLYRLMQRCWALSPKDRPSFSEIASALGDSTVDSKP
::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 AGKARLPQPEGCPSKLYRLMQRCWALSPKDRPSFSEIASALGDSTVDSKP
900 910 920 930 940
>>XP_011513068 (OMIM: 601890) PREDICTED: inactive tyrosi (948 aa)
initn: 3587 init1: 3587 opt: 3595 Z-score: 1316.9 bits: 255.2 E(85289): 1.3e-66
Smith-Waterman score: 5941; 86.1% identity (86.7% similar) in 1065 aa overlap (6-1070:17-948)
10 20 30 40
pF1KE3 MGAARGSPARPRRLPLLSVLLLPLLGGTQTAIVFIKQPSSQDALQGRRA
:: . ...: . : :::::::::::::::::::::::
XP_011 MGSFLSGEKRPSAPTVGSAMEKKEFPTPPGRVGP---GTQTAIVFIKQPSSQDALQGRRA
10 20 30 40 50
50 60 70 80 90 100
pF1KE3 LLRCEVEAPGPVHVYWLLDGAPVQDTERRFAQGSSLSFAAVDRLQDSGTFQCVARDDVTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLRCEVEAPGPVHVYWLLDGAPVQDTERRFAQGSSLSFAAVDRLQDSGTFQCVARDDVTG
60 70 80 90 100 110
110 120 130 140 150 160
pF1KE3 EEARSANASFNIKWIEAGPVVLKHPASEAEIQPQTQVTLRCHIDGHPRPTYQWFRDGTPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEARSANASFNIKWIEAGPVVLKHPASEAEIQPQTQVTLRCHIDGHPRPTYQWFRDGTPL
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE3 SDGQSNHTVSSKERNLTLRPAGPEHSGLYSCCAHSAFGQACSSQNFTLSIADESFARVVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SDGQSNHTVSSKERNLTLRPAGPEHSGLYSCCAHSAFGQACSSQNFTLSIADESFARVVL
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE3 APQDVVVARYEEAMFHCQFSAQPPPSLQWLFEDETPITNRSRPPHLRRATVFANGSLLLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 APQDVVVARYEEAMFHCQFSAQPPPSLQWLFEDETPITNRSRPPHLRRATVFANGSLLLT
240 250 260 270 280 290
290 300 310 320 330 340
pF1KE3 QVRPRNAGIYRCIGQGQRGPPIILEATLHLAEIEDMPLFEPRVFTAGSEERVTCLPPKGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QVRPRNAGIYRCIGQGQRGPPIILEATLHLAEIEDMPLFEPRVFTAGSEERVTCLPPKGL
300 310 320 330 340 350
350 360 370 380 390 400
pF1KE3 PEPSVWWEHAGVRLPTHGRVYQKGHELVLANIAESDAGVYTCHAANLAGQRRQDVNITVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PEPSVWWEHAGVRLPTHGRVYQKGHELVLANIAESDAGVYTCHAANLAGQRRQDVNITVA
360 370 380 390 400 410
410 420 430 440 450 460
pF1KE3 TVPSWLKKPQDSQLEEGKPGYLDCLTQATPKPTVVWYRNQMLISEDSRFEVFKNGTLRIN
XP_011 ------------------------------------------------------------
470 480 490 500 510 520
pF1KE3 SVEVYDGTWYRCMSSTPAGSIEAQARVQVLEKLKFTPPPQPQQCMEFDKEATVPCSATGR
XP_011 ------------------------------------------------------------
530 540 550 560 570 580
pF1KE3 EKPTIKWERADGSSLPEWVTDNAGTLHFARVTRDDAGNYTCIASNGPQGQIRAHVQLTVA
.:::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ----------NGSSLPEWVTDNAGTLHFARVTRDDAGNYTCIASNGPQGQIRAHVQLTVA
420 430 440 450 460
590 600 610 620 630 640
pF1KE3 VFITFKVEPERTTVYQGHTALLQCEAQGDPKPLIQWKGKDRILDPTKLGPRMHIFQNGSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VFITFKVEPERTTVYQGHTALLQCEAQGDPKPLIQWKGKDRILDPTKLGPRMHIFQNGSL
470 480 490 500 510 520
650 660 670 680 690 700
pF1KE3 VIHDVAPEDSGRYTCIAGNSCNIKHTEAPLYVVDKPVPEESEGPGSPPPYKMIQTIGLSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VIHDVAPEDSGRYTCIAGNSCNIKHTEAPLYVVDKPVPEESEGPGSPPPYKMIQTIGLSV
530 540 550 560 570 580
710 720 730 740 750 760
pF1KE3 GAAVAYIIAVLGLMFYCKKRCKAKRLQKQPEGEEPEMECLNGGPLQNGQPSAEIQEEVAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GAAVAYIIAVLGLMFYCKKRCKAKRLQKQPEGEEPEMECLNGGPLQNGQPSAEIQEEVAL
590 600 610 620 630 640
770 780 790 800 810 820
pF1KE3 TSLGSGPAATNKRHSTSDKMHFPRSSLQPITTLGKSEFGEVFLAKAQGLEEGVAETLVLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TSLGSGPAATNKRHSTSDKMHFPRSSLQPITTLGKSEFGEVFLAKAQGLEEGVAETLVLV
650 660 670 680 690 700
830 840 850 860 870 880
pF1KE3 KSLQSKDEQQQLDFRRELEMFGKLNHANVVRLLGLCREAEPHYMVLEYVDLGDLKQFLRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KSLQSKDEQQQLDFRRELEMFGKLNHANVVRLLGLCREAEPHYMVLEYVDLGDLKQFLRI
710 720 730 740 750 760
890 900 910 920 930 940
pF1KE3 SKSKDEKLKSQPLSTKQKVALCTQVALGMEHLSNNRFVHKDLAARNCLVSAQRQVKVSAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SKSKDEKLKSQPLSTKQKVALCTQVALGMEHLSNNRFVHKDLAARNCLVSAQRQVKVSAL
770 780 790 800 810 820
950 960 970 980 990 1000
pF1KE3 GLSKDVYNSEYYHFRQAWVPLRWMSPEAILEGDFSTKSDVWAFGVLMWEVFTHGEMPHGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLSKDVYNSEYYHFRQAWVPLRWMSPEAILEGDFSTKSDVWAFGVLMWEVFTHGEMPHGG
830 840 850 860 870 880
1010 1020 1030 1040 1050 1060
pF1KE3 QADDEVLADLQAGKARLPQPEGCPSKLYRLMQRCWALSPKDRPSFSEIASALGDSTVDSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QADDEVLADLQAGKARLPQPEGCPSKLYRLMQRCWALSPKDRPSFSEIASALGDSTVDSK
890 900 910 920 930 940
1070
pF1KE3 P
:
XP_011 P
>>NP_690619 (OMIM: 601890) inactive tyrosine-protein kin (1030 aa)
initn: 7033 init1: 3588 opt: 3588 Z-score: 1314.0 bits: 254.8 E(85289): 1.9e-66
Smith-Waterman score: 6908; 96.3% identity (96.3% similar) in 1070 aa overlap (1-1070:1-1030)
10 20 30 40 50 60
pF1KE3 MGAARGSPARPRRLPLLSVLLLPLLGGTQTAIVFIKQPSSQDALQGRRALLRCEVEAPGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 MGAARGSPARPRRLPLLSVLLLPLLGGTQTAIVFIKQPSSQDALQGRRALLRCEVEAPGP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 VHVYWLLDGAPVQDTERRFAQGSSLSFAAVDRLQDSGTFQCVARDDVTGEEARSANASFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 VHVYWLLDGAPVQDTERRFAQGSSLSFAAVDRLQDSGTFQCVARDDVTGEEARSANASFN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 IKWIEAGPVVLKHPASEAEIQPQTQVTLRCHIDGHPRPTYQWFRDGTPLSDGQSNHTVSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 IKWIEAGPVVLKHPASEAEIQPQTQVTLRCHIDGHPRPTYQWFRDGTPLSDGQSNHTVSS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 KERNLTLRPAGPEHSGLYSCCAHSAFGQACSSQNFTLSIADESFARVVLAPQDVVVARYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 KERNLTLRPAGPEHSGLYSCCAHSAFGQACSSQNFTLSIADESFARVVLAPQDVVVARYE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 EAMFHCQFSAQPPPSLQWLFEDETPITNRSRPPHLRRATVFANGSLLLTQVRPRNAGIYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 EAMFHCQFSAQPPPSLQWLFEDETPITNRSRPPHLRRATVFANGSLLLTQVRPRNAGIYR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 CIGQGQRGPPIILEATLHLAEIEDMPLFEPRVFTAGSEERVTCLPPKGLPEPSVWWEHAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 CIGQGQRGPPIILEATLHLAEIEDMPLFEPRVFTAGSEERVTCLPPKGLPEPSVWWEHAG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 VRLPTHGRVYQKGHELVLANIAESDAGVYTCHAANLAGQRRQDVNITVATVPSWLKKPQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 VRLPTHGRVYQKGHELVLANIAESDAGVYTCHAANLAGQRRQDVNITVATVPSWLKKPQD
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 SQLEEGKPGYLDCLTQATPKPTVVWYRNQMLISEDSRFEVFKNGTLRINSVEVYDGTWYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 SQLEEGKPGYLDCLTQATPKPTVVWYRNQMLISEDSRFEVFKNGTLRINSVEVYDGTWYR
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 CMSSTPAGSIEAQARVQVLEKLKFTPPPQPQQCMEFDKEATVPCSATGREKPTIKWERAD
::::::::::::::::::: :
NP_690 CMSSTPAGSIEAQARVQVL----------------------------------------D
490 500
550 560 570 580 590 600
pF1KE3 GSSLPEWVTDNAGTLHFARVTRDDAGNYTCIASNGPQGQIRAHVQLTVAVFITFKVEPER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 GSSLPEWVTDNAGTLHFARVTRDDAGNYTCIASNGPQGQIRAHVQLTVAVFITFKVEPER
510 520 530 540 550 560
610 620 630 640 650 660
pF1KE3 TTVYQGHTALLQCEAQGDPKPLIQWKGKDRILDPTKLGPRMHIFQNGSLVIHDVAPEDSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 TTVYQGHTALLQCEAQGDPKPLIQWKGKDRILDPTKLGPRMHIFQNGSLVIHDVAPEDSG
570 580 590 600 610 620
670 680 690 700 710 720
pF1KE3 RYTCIAGNSCNIKHTEAPLYVVDKPVPEESEGPGSPPPYKMIQTIGLSVGAAVAYIIAVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 RYTCIAGNSCNIKHTEAPLYVVDKPVPEESEGPGSPPPYKMIQTIGLSVGAAVAYIIAVL
630 640 650 660 670 680
730 740 750 760 770 780
pF1KE3 GLMFYCKKRCKAKRLQKQPEGEEPEMECLNGGPLQNGQPSAEIQEEVALTSLGSGPAATN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 GLMFYCKKRCKAKRLQKQPEGEEPEMECLNGGPLQNGQPSAEIQEEVALTSLGSGPAATN
690 700 710 720 730 740
790 800 810 820 830 840
pF1KE3 KRHSTSDKMHFPRSSLQPITTLGKSEFGEVFLAKAQGLEEGVAETLVLVKSLQSKDEQQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 KRHSTSDKMHFPRSSLQPITTLGKSEFGEVFLAKAQGLEEGVAETLVLVKSLQSKDEQQQ
750 760 770 780 790 800
850 860 870 880 890 900
pF1KE3 LDFRRELEMFGKLNHANVVRLLGLCREAEPHYMVLEYVDLGDLKQFLRISKSKDEKLKSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 LDFRRELEMFGKLNHANVVRLLGLCREAEPHYMVLEYVDLGDLKQFLRISKSKDEKLKSQ
810 820 830 840 850 860
910 920 930 940 950 960
pF1KE3 PLSTKQKVALCTQVALGMEHLSNNRFVHKDLAARNCLVSAQRQVKVSALGLSKDVYNSEY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 PLSTKQKVALCTQVALGMEHLSNNRFVHKDLAARNCLVSAQRQVKVSALGLSKDVYNSEY
870 880 890 900 910 920
970 980 990 1000 1010 1020
pF1KE3 YHFRQAWVPLRWMSPEAILEGDFSTKSDVWAFGVLMWEVFTHGEMPHGGQADDEVLADLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 YHFRQAWVPLRWMSPEAILEGDFSTKSDVWAFGVLMWEVFTHGEMPHGGQADDEVLADLQ
930 940 950 960 970 980
1030 1040 1050 1060 1070
pF1KE3 AGKARLPQPEGCPSKLYRLMQRCWALSPKDRPSFSEIASALGDSTVDSKP
::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 AGKARLPQPEGCPSKLYRLMQRCWALSPKDRPSFSEIASALGDSTVDSKP
990 1000 1010 1020 1030
>>XP_011513067 (OMIM: 601890) PREDICTED: inactive tyrosi (1038 aa)
initn: 6864 init1: 3588 opt: 3588 Z-score: 1314.0 bits: 254.8 E(85289): 1.9e-66
Smith-Waterman score: 6741; 94.6% identity (95.1% similar) in 1065 aa overlap (6-1070:17-1038)
10 20 30 40
pF1KE3 MGAARGSPARPRRLPLLSVLLLPLLGGTQTAIVFIKQPSSQDALQGRRA
:: . ...: . : :::::::::::::::::::::::
XP_011 MGSFLSGEKRPSAPTVGSAMEKKEFPTPPGRVGP---GTQTAIVFIKQPSSQDALQGRRA
10 20 30 40 50
50 60 70 80 90 100
pF1KE3 LLRCEVEAPGPVHVYWLLDGAPVQDTERRFAQGSSLSFAAVDRLQDSGTFQCVARDDVTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLRCEVEAPGPVHVYWLLDGAPVQDTERRFAQGSSLSFAAVDRLQDSGTFQCVARDDVTG
60 70 80 90 100 110
110 120 130 140 150 160
pF1KE3 EEARSANASFNIKWIEAGPVVLKHPASEAEIQPQTQVTLRCHIDGHPRPTYQWFRDGTPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEARSANASFNIKWIEAGPVVLKHPASEAEIQPQTQVTLRCHIDGHPRPTYQWFRDGTPL
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE3 SDGQSNHTVSSKERNLTLRPAGPEHSGLYSCCAHSAFGQACSSQNFTLSIADESFARVVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SDGQSNHTVSSKERNLTLRPAGPEHSGLYSCCAHSAFGQACSSQNFTLSIADESFARVVL
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE3 APQDVVVARYEEAMFHCQFSAQPPPSLQWLFEDETPITNRSRPPHLRRATVFANGSLLLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 APQDVVVARYEEAMFHCQFSAQPPPSLQWLFEDETPITNRSRPPHLRRATVFANGSLLLT
240 250 260 270 280 290
290 300 310 320 330 340
pF1KE3 QVRPRNAGIYRCIGQGQRGPPIILEATLHLAEIEDMPLFEPRVFTAGSEERVTCLPPKGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QVRPRNAGIYRCIGQGQRGPPIILEATLHLAEIEDMPLFEPRVFTAGSEERVTCLPPKGL
300 310 320 330 340 350
350 360 370 380 390 400
pF1KE3 PEPSVWWEHAGVRLPTHGRVYQKGHELVLANIAESDAGVYTCHAANLAGQRRQDVNITVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PEPSVWWEHAGVRLPTHGRVYQKGHELVLANIAESDAGVYTCHAANLAGQRRQDVNITVA
360 370 380 390 400 410
410 420 430 440 450 460
pF1KE3 TVPSWLKKPQDSQLEEGKPGYLDCLTQATPKPTVVWYRNQMLISEDSRFEVFKNGTLRIN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TVPSWLKKPQDSQLEEGKPGYLDCLTQATPKPTVVWYRNQMLISEDSRFEVFKNGTLRIN
420 430 440 450 460 470
470 480 490 500 510 520
pF1KE3 SVEVYDGTWYRCMSSTPAGSIEAQARVQVLEKLKFTPPPQPQQCMEFDKEATVPCSATGR
::::::::::::::::::::::::::::::
XP_011 SVEVYDGTWYRCMSSTPAGSIEAQARVQVL------------------------------
480 490 500
530 540 550 560 570 580
pF1KE3 EKPTIKWERADGSSLPEWVTDNAGTLHFARVTRDDAGNYTCIASNGPQGQIRAHVQLTVA
::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ----------DGSSLPEWVTDNAGTLHFARVTRDDAGNYTCIASNGPQGQIRAHVQLTVA
510 520 530 540 550
590 600 610 620 630 640
pF1KE3 VFITFKVEPERTTVYQGHTALLQCEAQGDPKPLIQWKGKDRILDPTKLGPRMHIFQNGSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VFITFKVEPERTTVYQGHTALLQCEAQGDPKPLIQWKGKDRILDPTKLGPRMHIFQNGSL
560 570 580 590 600 610
650 660 670 680 690 700
pF1KE3 VIHDVAPEDSGRYTCIAGNSCNIKHTEAPLYVVDKPVPEESEGPGSPPPYKMIQTIGLSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VIHDVAPEDSGRYTCIAGNSCNIKHTEAPLYVVDKPVPEESEGPGSPPPYKMIQTIGLSV
620 630 640 650 660 670
710 720 730 740 750 760
pF1KE3 GAAVAYIIAVLGLMFYCKKRCKAKRLQKQPEGEEPEMECLNGGPLQNGQPSAEIQEEVAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GAAVAYIIAVLGLMFYCKKRCKAKRLQKQPEGEEPEMECLNGGPLQNGQPSAEIQEEVAL
680 690 700 710 720 730
770 780 790 800 810 820
pF1KE3 TSLGSGPAATNKRHSTSDKMHFPRSSLQPITTLGKSEFGEVFLAKAQGLEEGVAETLVLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TSLGSGPAATNKRHSTSDKMHFPRSSLQPITTLGKSEFGEVFLAKAQGLEEGVAETLVLV
740 750 760 770 780 790
830 840 850 860 870 880
pF1KE3 KSLQSKDEQQQLDFRRELEMFGKLNHANVVRLLGLCREAEPHYMVLEYVDLGDLKQFLRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KSLQSKDEQQQLDFRRELEMFGKLNHANVVRLLGLCREAEPHYMVLEYVDLGDLKQFLRI
800 810 820 830 840 850
890 900 910 920 930 940
pF1KE3 SKSKDEKLKSQPLSTKQKVALCTQVALGMEHLSNNRFVHKDLAARNCLVSAQRQVKVSAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SKSKDEKLKSQPLSTKQKVALCTQVALGMEHLSNNRFVHKDLAARNCLVSAQRQVKVSAL
860 870 880 890 900 910
950 960 970 980 990 1000
pF1KE3 GLSKDVYNSEYYHFRQAWVPLRWMSPEAILEGDFSTKSDVWAFGVLMWEVFTHGEMPHGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLSKDVYNSEYYHFRQAWVPLRWMSPEAILEGDFSTKSDVWAFGVLMWEVFTHGEMPHGG
920 930 940 950 960 970
1010 1020 1030 1040 1050 1060
pF1KE3 QADDEVLADLQAGKARLPQPEGCPSKLYRLMQRCWALSPKDRPSFSEIASALGDSTVDSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QADDEVLADLQAGKARLPQPEGCPSKLYRLMQRCWALSPKDRPSFSEIASALGDSTVDSK
980 990 1000 1010 1020 1030
1070
pF1KE3 P
:
XP_011 P
>>NP_001007793 (OMIM: 155240,191315,256800) high affinit (760 aa)
initn: 701 init1: 241 opt: 730 Z-score: 294.5 bits: 65.7 E(85289): 1.1e-09
Smith-Waterman score: 810; 29.6% identity (58.9% similar) in 582 aa overlap (510-1061:171-745)
480 490 500 510 520 530
pF1KE3 RCMSSTPAGSIEAQARVQVLEKLKFTPPPQPQQCMEFDKEATVPCSATGREKPTIKW---
:. .. .. . :.. :: :
NP_001 PEQKLQCHGQGPLAHMPNASCGVPTLKVQVPNASVDVGDDVLLRCQVEGRGLEQAGWILT
150 160 170 180 190 200
540 550 560 570 580 590
pF1KE3 ERADGSSLPEWVTDNAGTLHFARVTRD-DAGNYTCIASNGPQGQIRAHVQLTVAVFITFK
: ..... . . : .: :: : . : :: : : : ::.: .: : ..:
NP_001 ELEQSATVMKSGGLPSLGLTLANVTSDLNRKNVTCWAENDV-G--RAEV--SVQVNVSFP
210 220 230 240 250
600 610 620 630 640
pF1KE3 VEPERTTVYQGHTALLQCEAQGDPKPLIQWKGKDRILDPTK------LGPRMH-IFQNGS
. . :. . : . ..:.: : ..: . .:. :. : : . ..:
NP_001 ASVQLHTAVEMHHWCIPFSVDGQPAPSLRWLFNGSVLNETSFIFTEFLEPAANETVRHGC
260 270 280 290 300 310
650 660 670 680 690 700
pF1KE3 LVIHDVAPEDSGRYTCIAGN-----SCNI--KHTEAPL-YVVDKPVPEESEGPGSPPPYK
: ... . ..: :: .:.: : .: . :. . . :.:. . :.: :
NP_001 LRLNQPTHVNNGNYTLLAANPFGQASASIMAAFMDNPFEFNPEDPIPDTNSTSGDPVEKK
320 330 340 350 360 370
710 720 730 740 750
pF1KE3 MIQTIGLSVGAAVAYIIAV-LGLMFYCKKRC--KAKRLQKQPEGEEPEMECLNGGPLQNG
.:.::....: . . :. .. ..: . : ..: :: . ...
NP_001 DETPFGVSVAVGLAVFACLFLSTLLLVLNKCGRRNKFGINRPAVLAPEDGLAMSLHFMTL
380 390 400 410 420 430
760 770 780 790 800 810
pF1KE3 QPSAEIQEEVALTSLGSGPAATNKRHSTSDKMHFPRSSLQPITTLGKSEFGEVFLAKAQG
:. : ..: . . . : . :. : .. ::.. ::.::::. ..
NP_001 GGSSLSPTEGKGSGLQGHIIENPQYFSDACVHHIKRRDIVLKWELGEGAFGKVFLAECHN
440 450 460 470 480 490
820 830 840 850 860 870
pF1KE3 LEEGVAETLVLVKSLQSKDEQQQLDFRRELEMFGKLNHANVVRLLGLCREAEPHYMVLEY
: . :: ::.:. .:. . ::.:: :.. :.: ..::..:.: :..: ::.::
NP_001 LLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEY
500 510 520 530 540 550
880 890 900 910 920 930
pF1KE3 VDLGDLKQFLRISKSKDEKLKSQ-------PLSTKQKVALCTQVALGMEHLSNNRFVHKD
. :::..::: :.. : :: . ::. : .:. .::: :: .:.. .:::.:
NP_001 MRHGDLNRFLR-SHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRD
560 570 580 590 600 610
940 950 960 970 980
pF1KE3 LAARNCLVSAQRQVKVSALGLSKDVYNSEYYHFR-QAWVPLRWMSPEAILEGDFSTKSDV
::.:::::. ::.. .:.:.:.:...::. .. .:.::: ::.:: :.:.:::
NP_001 LATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDV
620 630 640 650 660 670
990 1000 1010 1020 1030 1040
pF1KE3 WAFGVLMWEVFTHGEMPHGGQADDEVLADLQAGKARLPQPEGCPSKLYRLMQRCWALSPK
:.:::..::.::.:..: .. :.. . :. .: .:..:: ..: .:. :: :.
NP_001 WSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGR-ELERPRACPPEVYAIMRGCWQREPQ
680 690 700 710 720 730
1050 1060 1070
pF1KE3 DRPSFSEIASALGDSTVDSKP
.: :.... . :
NP_001 QRHSIKDVHARLQALAQAPPVYLDVLG
740 750 760
>>NP_001012331 (OMIM: 155240,191315,256800) high affinit (790 aa)
initn: 701 init1: 241 opt: 730 Z-score: 294.4 bits: 65.7 E(85289): 1.2e-09
Smith-Waterman score: 810; 29.6% identity (58.9% similar) in 582 aa overlap (510-1061:201-775)
480 490 500 510 520 530
pF1KE3 RCMSSTPAGSIEAQARVQVLEKLKFTPPPQPQQCMEFDKEATVPCSATGREKPTIKW---
:. .. .. . :.. :: :
NP_001 PEQKLQCHGQGPLAHMPNASCGVPTLKVQVPNASVDVGDDVLLRCQVEGRGLEQAGWILT
180 190 200 210 220 230
540 550 560 570 580 590
pF1KE3 ERADGSSLPEWVTDNAGTLHFARVTRD-DAGNYTCIASNGPQGQIRAHVQLTVAVFITFK
: ..... . . : .: :: : . : :: : : : ::.: .: : ..:
NP_001 ELEQSATVMKSGGLPSLGLTLANVTSDLNRKNVTCWAENDV-G--RAEV--SVQVNVSFP
240 250 260 270 280
600 610 620 630 640
pF1KE3 VEPERTTVYQGHTALLQCEAQGDPKPLIQWKGKDRILDPTK------LGPRMH-IFQNGS
. . :. . : . ..:.: : ..: . .:. :. : : . ..:
NP_001 ASVQLHTAVEMHHWCIPFSVDGQPAPSLRWLFNGSVLNETSFIFTEFLEPAANETVRHGC
290 300 310 320 330 340
650 660 670 680 690 700
pF1KE3 LVIHDVAPEDSGRYTCIAGN-----SCNI--KHTEAPL-YVVDKPVPEESEGPGSPPPYK
: ... . ..: :: .:.: : .: . :. . . :.:. . :.: :
NP_001 LRLNQPTHVNNGNYTLLAANPFGQASASIMAAFMDNPFEFNPEDPIPDTNSTSGDPVEKK
350 360 370 380 390 400
710 720 730 740 750
pF1KE3 MIQTIGLSVGAAVAYIIAV-LGLMFYCKKRC--KAKRLQKQPEGEEPEMECLNGGPLQNG
.:.::....: . . :. .. ..: . : ..: :: . ...
NP_001 DETPFGVSVAVGLAVFACLFLSTLLLVLNKCGRRNKFGINRPAVLAPEDGLAMSLHFMTL
410 420 430 440 450 460
760 770 780 790 800 810
pF1KE3 QPSAEIQEEVALTSLGSGPAATNKRHSTSDKMHFPRSSLQPITTLGKSEFGEVFLAKAQG
:. : ..: . . . : . :. : .. ::.. ::.::::. ..
NP_001 GGSSLSPTEGKGSGLQGHIIENPQYFSDACVHHIKRRDIVLKWELGEGAFGKVFLAECHN
470 480 490 500 510 520
820 830 840 850 860 870
pF1KE3 LEEGVAETLVLVKSLQSKDEQQQLDFRRELEMFGKLNHANVVRLLGLCREAEPHYMVLEY
: . :: ::.:. .:. . ::.:: :.. :.: ..::..:.: :..: ::.::
NP_001 LLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRPLLMVFEY
530 540 550 560 570 580
880 890 900 910 920 930
pF1KE3 VDLGDLKQFLRISKSKDEKLKSQ-------PLSTKQKVALCTQVALGMEHLSNNRFVHKD
. :::..::: :.. : :: . ::. : .:. .::: :: .:.. .:::.:
NP_001 MRHGDLNRFLR-SHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAGLHFVHRD
590 600 610 620 630 640
940 950 960 970 980
pF1KE3 LAARNCLVSAQRQVKVSALGLSKDVYNSEYYHFR-QAWVPLRWMSPEAILEGDFSTKSDV
::.:::::. ::.. .:.:.:.:...::. .. .:.::: ::.:: :.:.:::
NP_001 LATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRKFTTESDV
650 660 670 680 690 700
990 1000 1010 1020 1030 1040
pF1KE3 WAFGVLMWEVFTHGEMPHGGQADDEVLADLQAGKARLPQPEGCPSKLYRLMQRCWALSPK
:.:::..::.::.:..: .. :.. . :. .: .:..:: ..: .:. :: :.
NP_001 WSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGR-ELERPRACPPEVYAIMRGCWQREPQ
710 720 730 740 750 760
1050 1060 1070
pF1KE3 DRPSFSEIASALGDSTVDSKP
.: :.... . :
NP_001 QRHSIKDVHARLQALAQAPPVYLDVLG
770 780 790
>>NP_002520 (OMIM: 155240,191315,256800) high affinity n (796 aa)
initn: 684 init1: 241 opt: 725 Z-score: 292.6 bits: 65.4 E(85289): 1.5e-09
Smith-Waterman score: 790; 29.7% identity (58.4% similar) in 589 aa overlap (510-1061:201-781)
480 490 500 510 520 530
pF1KE3 RCMSSTPAGSIEAQARVQVLEKLKFTPPPQPQQCMEFDKEATVPCSATGREKPTIKW---
:. .. .. . :.. :: :
NP_002 PEQKLQCHGQGPLAHMPNASCGVPTLKVQVPNASVDVGDDVLLRCQVEGRGLEQAGWILT
180 190 200 210 220 230
540 550 560 570 580 590
pF1KE3 ERADGSSLPEWVTDNAGTLHFARVTRD-DAGNYTCIASNGPQGQIRAHVQLTVAVFITFK
: ..... . . : .: :: : . : :: : : : ::.: .: : ..:
NP_002 ELEQSATVMKSGGLPSLGLTLANVTSDLNRKNVTCWAENDV-G--RAEV--SVQVNVSFP
240 250 260 270 280
600 610 620 630 640
pF1KE3 VEPERTTVYQGHTALLQCEAQGDPKPLIQWKGKDRILDPTK------LGPRMH-IFQNGS
. . :. . : . ..:.: : ..: . .:. :. : : . ..:
NP_002 ASVQLHTAVEMHHWCIPFSVDGQPAPSLRWLFNGSVLNETSFIFTEFLEPAANETVRHGC
290 300 310 320 330 340
650 660 670 680 690
pF1KE3 LVIHDVAPEDSGRYTCIAGN-----SCNIK----------HTEAPLYVVDKPVPEESEGP
: ... . ..: :: .:.: : .: . : :. : .:: .: .
NP_002 LRLNQPTHVNNGNYTLLAANPFGQASASIMAAFMDNPFEFNPEDPIPVSFSPVDTNSTS-
350 360 370 380 390 400
700 710 720 730 740 750
pF1KE3 GSPPPYKMIQTIGLSVGAAVAYIIAV-LGLMFYCKKRC--KAKRLQKQPEGEEPEMECLN
:.: : .:.::....: . . :. .. ..: . : ..: ::
NP_002 GDPVEKKDETPFGVSVAVGLAVFACLFLSTLLLVLNKCGRRNKFGINRPAVLAPEDGLAM
410 420 430 440 450 460
760 770 780 790 800 810
pF1KE3 GGPLQNGQPSAEIQEEVALTSLGSGPAATNKRHSTSDKMHFPRSSLQPITTLGKSEFGEV
. ... :. : ..: . . . : . :. : .. ::.. ::.:
NP_002 SLHFMTLGGSSLSPTEGKGSGLQGHIIENPQYFSDACVHHIKRRDIVLKWELGEGAFGKV
470 480 490 500 510 520
820 830 840 850 860 870
pF1KE3 FLAKAQGLEEGVAETLVLVKSLQSKDEQQQLDFRRELEMFGKLNHANVVRLLGLCREAEP
:::. ..: . :: ::.:. .:. . ::.:: :.. :.: ..::..:.: :..:
NP_002 FLAECHNLLPEQDKMLVAVKALKEASESARQDFQREAELLTMLQHQHIVRFFGVCTEGRP
530 540 550 560 570 580
880 890 900 910 920
pF1KE3 HYMVLEYVDLGDLKQFLRISKSKDEKLKSQ-------PLSTKQKVALCTQVALGMEHLSN
::.::. :::..::: :.. : :: . ::. : .:. .::: :: .:..
NP_002 LLMVFEYMRHGDLNRFLR-SHGPDAKLLAGGEDVAPGPLGLGQLLAVASQVAAGMVYLAG
590 600 610 620 630 640
930 940 950 960 970 980
pF1KE3 NRFVHKDLAARNCLVSAQRQVKVSALGLSKDVYNSEYYHFR-QAWVPLRWMSPEAILEGD
.:::.:::.:::::. ::.. .:.:.:.:...::. .. .:.::: ::.::
NP_002 LHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDYYRVGGRTMLPIRWMPPESILYRK
650 660 670 680 690 700
990 1000 1010 1020 1030 1040
pF1KE3 FSTKSDVWAFGVLMWEVFTHGEMPHGGQADDEVLADLQAGKARLPQPEGCPSKLYRLMQR
:.:.::::.:::..::.::.:..: .. :.. . :. .: .:..:: ..: .:.
NP_002 FTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGR-ELERPRACPPEVYAIMRG
710 720 730 740 750 760
1050 1060 1070
pF1KE3 CWALSPKDRPSFSEIASALGDSTVDSKP
:: :..: :.... . :
NP_002 CWQREPQQRHSIKDVHARLQALAQAPPVYLDVLG
770 780 790
1070 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Wed Nov 16 15:01:11 2016 done: Wed Nov 16 15:01:13 2016
Total Scan time: 13.380 Total Display time: 0.260
Function used was FASTA [36.3.4 Apr, 2011]