Result of FASTA (ccds) for
pFN21AE3325
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3325, 921 aa
1>>>pF1KE3325 921 - 921 aa - 921 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 13.3235+/-0.00111; mu= -15.0355+/- 0.067
mean_var=460.1184+/-99.849, 0's: 0 Z-trim(115.2): 179 B-trim: 0 in 0/52
Lambda= 0.059791
statistics sampled from 15551 (15729) to 15551 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.772), E-opt: 0.2 (0.483), width: 16
Scan time: 5.010
The best scores are: opt bits E(32554)
CCDS61250.1 KSR2 gene_id:283455|Hs108|chr12 ( 921) 6375 564.9 2.4e-160
CCDS58532.1 KSR1 gene_id:8844|Hs108|chr17 ( 762) 1701 161.7 4.8e-39
>>CCDS61250.1 KSR2 gene_id:283455|Hs108|chr12 (921 aa)
initn: 6375 init1: 6375 opt: 6375 Z-score: 2992.3 bits: 564.9 E(32554): 2.4e-160
Smith-Waterman score: 6375; 100.0% identity (100.0% similar) in 921 aa overlap (1-921:1-921)
10 20 30 40 50 60
pF1KE3 MIDLSISNLEGLRTKCATSNDLTQKEIRTLESKLVKYFSRQLSCKKKVALQERNAELDGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS61 MIDLSISNLEGLRTKCATSNDLTQKEIRTLESKLVKYFSRQLSCKKKVALQERNAELDGF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 PQLRHWFRIVDVRKEVLEEISPGQLSLEDLLEMTDEQVCETVEKYGANREECARLNASLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS61 PQLRHWFRIVDVRKEVLEEISPGQLSLEDLLEMTDEQVCETVEKYGANREECARLNASLS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 CLRNVHMSGGNLSKQDWTIQWPTTETGKENNPVCPPEPTPWIRTHLSQSPRVPSKCVQHY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS61 CLRNVHMSGGNLSKQDWTIQWPTTETGKENNPVCPPEPTPWIRTHLSQSPRVPSKCVQHY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 CHTSPTPGAPVYTHVDRLTVDAYPGLCPPPPLESGHRSLPPSPRQRHAVRTPPRTPNIVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS61 CHTSPTPGAPVYTHVDRLTVDAYPGLCPPPPLESGHRSLPPSPRQRHAVRTPPRTPNIVT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 TVTPPGTPPMRKKNKLKPPGTPPPSSRKLIHLIPGFTALHRSKSHEFQLGHRVDEAHTPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS61 TVTPPGTPPMRKKNKLKPPGTPPPSSRKLIHLIPGFTALHRSKSHEFQLGHRVDEAHTPK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 AKKKSKPLNLKIHSSVGSCENIPSQQRSPLLSERSLRSFFVGHAPFLPSTPPVHTEANFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS61 AKKKSKPLNLKIHSSVGSCENIPSQQRSPLLSERSLRSFFVGHAPFLPSTPPVHTEANFS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 ANTLSVPRWSPQIPRRDLGNSIKHRFSTKYWMSQTCTVCGKGMLFGLKCKNCKLKCHNKC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS61 ANTLSVPRWSPQIPRRDLGNSIKHRFSTKYWMSQTCTVCGKGMLFGLKCKNCKLKCHNKC
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 TKEAPPCHLLIIHRGDPARLVRTESVPCDINNPLRKPPRYSDLHISQTLPKTNKINKDHI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS61 TKEAPPCHLLIIHRGDPARLVRTESVPCDINNPLRKPPRYSDLHISQTLPKTNKINKDHI
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 PVPYQPDSSSNPSSTTSSTPSSPAPPLPPSATPPSPLHPSPQCTRQQKNFNLPASHYYKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS61 PVPYQPDSSSNPSSTTSSTPSSPAPPLPPSATPPSPLHPSPQCTRQQKNFNLPASHYYKY
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 KQQFIFPDVVPVPETPTRAPQVILHPVTSNPILEGNPLLQIEVEPTSENEEVHDEAEESE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS61 KQQFIFPDVVPVPETPTRAPQVILHPVTSNPILEGNPLLQIEVEPTSENEEVHDEAEESE
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 DDFEEMNLSLLSARSFPRKASQTSIFLQEWDIPFEQLEIGELIGKGRFGQVYHGRWHGEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS61 DDFEEMNLSLLSARSFPRKASQTSIFLQEWDIPFEQLEIGELIGKGRFGQVYHGRWHGEV
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 AIRLIDIERDNEDQLKAFKREVMAYRQTRHENVVLFMGACMSPPHLAIITSLCKGRTLYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS61 AIRLIDIERDNEDQLKAFKREVMAYRQTRHENVVLFMGACMSPPHLAIITSLCKGRTLYS
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 VVRDAKIVLDVNKTRQIAQEIVKGMGYLHAKGILHKDLKSKNVFYDNGKVVITDFGLFSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS61 VVRDAKIVLDVNKTRQIAQEIVKGMGYLHAKGILHKDLKSKNVFYDNGKVVITDFGLFSI
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE3 SGVLQAGRREDKLRIQNGWLCHLAPEIIRQLSPDTEEDKLPFSKHSDVFALGTIWYELHA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS61 SGVLQAGRREDKLRIQNGWLCHLAPEIIRQLSPDTEEDKLPFSKHSDVFALGTIWYELHA
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE3 REWPFKTQPAEAIIWQMGTGMKPNLSQIGMGKEISDILLFCWAFEQEERPTFTKLMDMLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS61 REWPFKTQPAEAIIWQMGTGMKPNLSQIGMGKEISDILLFCWAFEQEERPTFTKLMDMLE
850 860 870 880 890 900
910 920
pF1KE3 KLPKRNRRLSHPGHFWKSAEL
:::::::::::::::::::::
CCDS61 KLPKRNRRLSHPGHFWKSAEL
910 920
>>CCDS58532.1 KSR1 gene_id:8844|Hs108|chr17 (762 aa)
initn: 2153 init1: 1305 opt: 1701 Z-score: 814.5 bits: 161.7 E(32554): 4.8e-39
Smith-Waterman score: 2449; 48.7% identity (69.6% similar) in 859 aa overlap (93-921:1-762)
70 80 90 100 110 120
pF1KE3 LRHWFRIVDVRKEVLEEISPGQLSLEDLLEMTDEQVCETVEKYGANREECARLNASLSCL
:.. .: ::... ::. .::.::. .:.::
CCDS58 MNEAKVKETLRRCGASGDECGRLQYALTCL
10 20 30
130 140 150 160 170 180
pF1KE3 RNVHMSGGNLSKQDWTIQWPTTETGKENNPVCPPEPTPWIRTHLSQSPRVPSKCVQHYCH
:.: ::. :.: . : . .. .:.. : . : : :. . . .
CCDS58 RKVTGLGGE-HKEDSS--WSSLDARRESGS--GPSTDTLSAASLPWPP--GSSQLGRAGN
40 50 60 70 80
190 200 210 220 230 240
pF1KE3 TSPTPGAPVYTHVDRLTVDAYPGLCPPPPLESGHRSLPPSPRQRHAV-RTPPRTPNIVTT
.. : . ..:.: :. : : : ..: . :: : ::. . .
CCDS58 SAQGPRS--------ISVSALPASDSPTP--SFSEGLSDTCIPLHASGRLTPRA--LHSF
90 100 110 120 130
250 260 270 280 290 300
pF1KE3 VTPPGTPPMRKKNKLKPPGTPPPSSRKLIHLIPGFTALHRSKSHEFQLGHRVDEAHTPKA
.::: :: .:...::::: :::: :::...:.:.: .: :::::: :::.:.:..
CCDS58 ITPPTTPQLRRHTKLKPPRTPPPPSRKVFQLLPSFPTLTRSKSHESQLGNRIDDVS----
140 150 160 170 180
310 320 330 340 350 360
pF1KE3 KKKSKPLNLKIHSSVGSCENIPSQQRSPLLSERSLRSFFVGHAPFLPSTPPVHTEANFSA
:.: : ..:.
CCDS58 ---------------------------------SMR-FDLSHG-----------------
190
370 380 390 400 410 420
pF1KE3 NTLSVPRWSPQIPRRDLGNSIKHRFSTKYWMSQTCTVCGKGMLFGLKCKNCKLKCHNKCT
:::. :::.: :. :::::: :.::.: :: :.:.::.:::.:.::::::::
CCDS58 --------SPQMVRRDIGLSVTHRFSTKSWLSQVCHVCQKSMIFGVKCKHCRLKCHNKCT
200 210 220 230 240
430 440 450 460 470 480
pF1KE3 KEAPPCHLLIIHRGDP-ARLVRTESVPCDINNPLRKPPRYSDLHISQTLPKTNKINKDHI
:::: :.. .. : .:: :::::: :::::. : .. :.. ::::. .:.:
CCDS58 KEAPACRISFL----PLTRLRRTESVPSDINNPV---DRAAEPHFG-TLPKA-LTKKEHP
250 260 270 280 290
490 500 510 520 530
pF1KE3 PVPYQPDSSSNPSSTTSSTPSSPAPPLPPSATPPS---PLHPSPQCTRQQKNFNLPASHY
:. . ::::::::::::::::::: .: :..: : : .::: .... ::.::...
CCDS58 PAMNHLDSSSNPSSTTSSTPSSPAP-FPTSSNPSSATTPPNPSPG--QRDSRFNFPAAYF
300 310 320 330 340 350
540 550 560 570 580
pF1KE3 YKYKQQFIFPDVVP----------VPETPTRAPQVILHPVTSNPILEGNPLLQIEVEPTS
...:::::: :: . :. . : . . :. :. ... .: .
CCDS58 IHHRQQFIFP--VPSAGHCWKCLLIAESLKENAFNISAFAHAAPLPEAADGTRLDDQPKA
360 370 380 390 400 410
590 600 610 620 630
pF1KE3 ENEEVHD-EAEE-------SEDDFEEMNLSLLSARS-----FPRKASQTSIFLQEWDIPF
. :.:. :::: .::: .:.. .: :.: . :::::::..::::::::
CCDS58 DVLEAHEAEAEEPEAGKSEAEDDEDEVD-DLPSSRRPWRGPISRKASQTSVYLQEWDIPF
420 430 440 450 460 470
640 650 660 670 680 690
pF1KE3 EQLEIGELIGKGRFGQVYHGRWHGEVAIRLIDIERDNEDQLKAFKREVMAYRQTRHENVV
::.:.:: ::.::.:.:..:::::::::::.... :.:.:: ::.::: ::::::::::
CCDS58 EQVELGEPIGQGRWGRVHRGRWHGEVAIRLLEMDGHNQDHLKLFKKEVMNYRQTRHENVV
480 490 500 510 520 530
700 710 720 730 740 750
pF1KE3 LFMGACMSPPHLAIITSLCKGRTLYSVVRDAKIVLDVNKTRQIAQEIVKGMGYLHAKGIL
:::::::.:::::::::.::::::.: ::: : ::.::::::::::.:::::::::::.
CCDS58 LFMGACMNPPHLAIITSFCKGRTLHSFVRDPKTSLDINKTRQIAQEIIKGMGYLHAKGIV
540 550 560 570 580 590
760 770 780 790 800 810
pF1KE3 HKDLKSKNVFYDNGKVVITDFGLFSISGVLQAGRREDKLRIQNGWLCHLAPEIIRQLSPD
::::::::::::::::::::::::.::::.. ::::..:.... :::.:::::.:...:
CCDS58 HKDLKSKNVFYDNGKVVITDFGLFGISGVVREGRRENQLKLSHDWLCYLAPEIVREMTPG
600 610 620 630 640 650
820 830 840 850 860 870
pF1KE3 TEEDKLPFSKHSDVFALGTIWYELHAREWPFKTQPAEAIIWQMGTG--MKPNLSQIGMGK
.::.::::: .::.:.::.::::.::.::.:.: ::: :::.:.: :: :.....::
CCDS58 KDEDQLPFSKAADVYAFGTVWYELQARDWPLKNQAAEASIWQIGSGEGMKRVLTSVSLGK
660 670 680 690 700 710
880 890 900 910 920
pF1KE3 EISDILLFCWAFEQEERPTFTKLMDMLEKLPKRNRRLSHPGHFWKSAEL
:.:.:: ::::. .:::.:. :::::::::: ::::::::::::::::
CCDS58 EVSEILSACWAFDLQERPSFSLLMDMLEKLPKLNRRLSHPGHFWKSAEL
720 730 740 750 760
921 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 16:12:14 2016 done: Mon Nov 7 16:12:14 2016
Total Scan time: 5.010 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]