Result of FASTA (omim) for
pFN21AE3312
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3312, 795 aa
1>>>pF1KE3312 795 - 795 aa - 795 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.1985+/-0.000602; mu= 4.4368+/- 0.037
mean_var=556.2175+/-121.226, 0's: 0 Z-trim(117.8): 2039 B-trim: 33 in 1/55
Lambda= 0.054382
statistics sampled from 27271 (30052) to 27271 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.683), E-opt: 0.2 (0.352), width: 16
Scan time: 11.810
The best scores are: opt bits E(85289)
XP_006713373 (OMIM: 601959) PREDICTED: serine/thre ( 795) 5220 426.0 3.2e-118
XP_016862575 (OMIM: 601959) PREDICTED: serine/thre ( 824) 5025 410.7 1.3e-113
XP_011532342 (OMIM: 601959) PREDICTED: serine/thre ( 671) 3047 255.4 6.1e-67
NP_003148 (OMIM: 601959) serine/threonine-protein ( 841) 3047 255.5 6.8e-67
XP_011532341 (OMIM: 601959) PREDICTED: serine/thre ( 842) 3047 255.5 6.8e-67
XP_016862574 (OMIM: 601959) PREDICTED: serine/thre ( 870) 3047 255.6 6.9e-67
NP_001180462 (OMIM: 601959) serine/threonine-prote ( 752) 2256 193.4 3.1e-48
XP_011530306 (OMIM: 263520,604588) PREDICTED: seri (1214) 988 94.3 3.5e-18
NP_001186329 (OMIM: 263520,604588) serine/threonin (1214) 988 94.3 3.5e-18
XP_011530307 (OMIM: 263520,604588) PREDICTED: seri ( 715) 979 93.2 4.3e-18
NP_001186328 (OMIM: 263520,604588) serine/threonin (1189) 979 93.5 5.6e-18
XP_006714291 (OMIM: 263520,604588) PREDICTED: seri (1227) 979 93.6 5.7e-18
NP_001186327 (OMIM: 263520,604588) serine/threonin (1242) 979 93.6 5.7e-18
NP_036356 (OMIM: 263520,604588) serine/threonine-p (1258) 979 93.6 5.8e-18
XP_011530305 (OMIM: 263520,604588) PREDICTED: seri (1258) 979 93.6 5.8e-18
NP_001186326 (OMIM: 263520,604588) serine/threonin (1286) 979 93.6 5.8e-18
NP_001139571 (OMIM: 604044) serine/threonine-prote ( 489) 848 82.6 4.5e-15
XP_011533370 (OMIM: 616731) PREDICTED: serine/thre ( 483) 846 82.5 4.9e-15
XP_006719871 (OMIM: 616731) PREDICTED: serine/thre ( 598) 846 82.6 5.5e-15
XP_011533368 (OMIM: 616731) PREDICTED: serine/thre ( 697) 846 82.7 5.9e-15
NP_689933 (OMIM: 604044) serine/threonine-protein ( 506) 843 82.3 6e-15
NP_002489 (OMIM: 604044) serine/threonine-protein ( 506) 843 82.3 6e-15
NP_954983 (OMIM: 616731) serine/threonine-protein ( 708) 846 82.7 6e-15
XP_016876045 (OMIM: 616731) PREDICTED: serine/thre ( 737) 846 82.8 6.1e-15
XP_016876044 (OMIM: 616731) PREDICTED: serine/thre ( 755) 846 82.8 6.2e-15
XP_016876046 (OMIM: 616731) PREDICTED: serine/thre ( 780) 846 82.8 6.3e-15
NP_665917 (OMIM: 609779) serine/threonine-protein ( 470) 788 77.9 1.1e-13
NP_001139475 (OMIM: 609779) serine/threonine-prote ( 599) 790 78.2 1.2e-13
XP_016862702 (OMIM: 609779) PREDICTED: serine/thre ( 599) 790 78.2 1.2e-13
XP_016862703 (OMIM: 609779) PREDICTED: serine/thre ( 599) 790 78.2 1.2e-13
NP_001308152 (OMIM: 609779) serine/threonine-prote ( 482) 788 77.9 1.2e-13
XP_011511469 (OMIM: 609779) PREDICTED: serine/thre ( 645) 790 78.3 1.2e-13
NP_001308149 (OMIM: 609779) serine/threonine-prote ( 645) 790 78.3 1.2e-13
NP_079076 (OMIM: 609779) serine/threonine-protein ( 645) 790 78.3 1.2e-13
XP_016862704 (OMIM: 609779) PREDICTED: serine/thre ( 563) 788 78.0 1.3e-13
XP_016862705 (OMIM: 609779) PREDICTED: serine/thre ( 563) 788 78.0 1.3e-13
XP_016862701 (OMIM: 609779) PREDICTED: serine/thre ( 609) 788 78.1 1.3e-13
NP_835464 (OMIM: 609799,613824,615415) serine/thre ( 692) 752 75.3 9.8e-13
XP_016879988 (OMIM: 609799,613824,615415) PREDICTE ( 705) 730 73.6 3.3e-12
NP_149107 (OMIM: 609798,614262,617022,617025) seri ( 979) 712 72.5 1e-11
NP_001316166 (OMIM: 609798,614262,617022,617025) s ( 991) 712 72.5 1e-11
XP_011522942 (OMIM: 609799,613824,615415) PREDICTE ( 716) 700 71.3 1.7e-11
XP_016879990 (OMIM: 609799,613824,615415) PREDICTE ( 484) 678 69.3 4.6e-11
XP_011522940 (OMIM: 609799,613824,615415) PREDICTE ( 729) 678 69.6 5.6e-11
XP_016862711 (OMIM: 609779) PREDICTED: serine/thre ( 512) 651 67.2 2.1e-10
XP_016862700 (OMIM: 609779) PREDICTED: serine/thre ( 641) 653 67.5 2.1e-10
XP_016862710 (OMIM: 609779) PREDICTED: serine/thre ( 524) 651 67.2 2.1e-10
XP_016862709 (OMIM: 609779) PREDICTED: serine/thre ( 526) 651 67.2 2.1e-10
XP_016862695 (OMIM: 609779) PREDICTED: serine/thre ( 687) 653 67.6 2.1e-10
XP_016862694 (OMIM: 609779) PREDICTED: serine/thre ( 687) 653 67.6 2.1e-10
>>XP_006713373 (OMIM: 601959) PREDICTED: serine/threonin (795 aa)
initn: 5220 init1: 5220 opt: 5220 Z-score: 2243.5 bits: 426.0 E(85289): 3.2e-118
Smith-Waterman score: 5220; 100.0% identity (100.0% similar) in 795 aa overlap (1-795:1-795)
10 20 30 40 50 60
pF1KE3 MPLAAYCYLRVVGKGSYGEVTLVKHRRDGKQYVIKKLNLRNASSRERRAAEQEAQLLSQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MPLAAYCYLRVVGKGSYGEVTLVKHRRDGKQYVIKKLNLRNASSRERRAAEQEAQLLSQL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 KHPNIVTYKESWEGGDGLLYIVMGFCEGGDLYRKLKEQKGQLLPENQVVEWFVQIAMALQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KHPNIVTYKESWEGGDGLLYIVMGFCEGGDLYRKLKEQKGQLLPENQVVEWFVQIAMALQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 YLHEKHILHRDLKTQNVFLTRTNIIKVGDLGIARVLENHCDMASTLIGTPYYMSPELFSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YLHEKHILHRDLKTQNVFLTRTNIIKVGDLGIARVLENHCDMASTLIGTPYYMSPELFSN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 KPYNYKSDVWALGCCVYEMATLKHAFNAKDMNSLVYRIIEGKLPPMPRDYSPELAELIRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KPYNYKSDVWALGCCVYEMATLKHAFNAKDMNSLVYRIIEGKLPPMPRDYSPELAELIRT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 MLSKRPEERPSVRSILRQPYIKRQISFFLEATKIKTSKNNIKNGDSQSKPFATVVSGEAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MLSKRPEERPSVRSILRQPYIKRQISFFLEATKIKTSKNNIKNGDSQSKPFATVVSGEAE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 SNHEVIHPQPLSSEGSQTYIMGEGKCLSQEKPRASGLLKSPASLKAHTCKQDLSNTTELA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SNHEVIHPQPLSSEGSQTYIMGEGKCLSQEKPRASGLLKSPASLKAHTCKQDLSNTTELA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 TISSVNIDILPAKGRDSVSDGFVQENQPRYLDASNELGGICSISQVEEEMLQDNTKSSAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TISSVNIDILPAKGRDSVSDGFVQENQPRYLDASNELGGICSISQVEEEMLQDNTKSSAQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 PENLIPMWSSDIVTGEKNEPVKPLQPLIKEQKPKDQDQVAGECIIEKQGRIHPDLQPHNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PENLIPMWSSDIVTGEKNEPVKPLQPLIKEQKPKDQDQVAGECIIEKQGRIHPDLQPHNS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 GSEPSLSRQRRQKRREQTEHRGEKRQVRRDLFAFQESPPRFLPSHPIVGKVDVTSTQKEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GSEPSLSRQRRQKRREQTEHRGEKRQVRRDLFAFQESPPRFLPSHPIVGKVDVTSTQKEA
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 ENQRRVVTGSVSSSRSSEMSSSKDRPLSARERRRLKQSQEEMSSSGPSVRKASLSVAGPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ENQRRVVTGSVSSSRSSEMSSSKDRPLSARERRRLKQSQEEMSSSGPSVRKASLSVAGPG
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 KPQEEDQPLPARRLSSDCSVTQERKQIHCLSEDELSSSTSSTDKSDGDYGEGKGQTNEIN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KPQEEDQPLPARRLSSDCSVTQERKQIHCLSEDELSSSTSSTDKSDGDYGEGKGQTNEIN
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 ALVQLMTQTLKLDSKESCEDVPVANPVSEFKLHRKYRDTLILHGKVAEEAEEIHFKELPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ALVQLMTQTLKLDSKESCEDVPVANPVSEFKLHRKYRDTLILHGKVAEEAEEIHFKELPS
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 AIMPGSEKIRRLVEVLRTDVIRGLGVQLLEQVYDLLEEEDEFDREVRLREHMGEKYTTYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AIMPGSEKIRRLVEVLRTDVIRGLGVQLLEQVYDLLEEEDEFDREVRLREHMGEKYTTYS
730 740 750 760 770 780
790
pF1KE3 VKARQLKFFEENMNF
:::::::::::::::
XP_006 VKARQLKFFEENMNF
790
>>XP_016862575 (OMIM: 601959) PREDICTED: serine/threonin (824 aa)
initn: 5025 init1: 5025 opt: 5025 Z-score: 2160.7 bits: 410.7 E(85289): 1.3e-113
Smith-Waterman score: 5025; 99.9% identity (100.0% similar) in 766 aa overlap (1-766:1-766)
10 20 30 40 50 60
pF1KE3 MPLAAYCYLRVVGKGSYGEVTLVKHRRDGKQYVIKKLNLRNASSRERRAAEQEAQLLSQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MPLAAYCYLRVVGKGSYGEVTLVKHRRDGKQYVIKKLNLRNASSRERRAAEQEAQLLSQL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 KHPNIVTYKESWEGGDGLLYIVMGFCEGGDLYRKLKEQKGQLLPENQVVEWFVQIAMALQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KHPNIVTYKESWEGGDGLLYIVMGFCEGGDLYRKLKEQKGQLLPENQVVEWFVQIAMALQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 YLHEKHILHRDLKTQNVFLTRTNIIKVGDLGIARVLENHCDMASTLIGTPYYMSPELFSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YLHEKHILHRDLKTQNVFLTRTNIIKVGDLGIARVLENHCDMASTLIGTPYYMSPELFSN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 KPYNYKSDVWALGCCVYEMATLKHAFNAKDMNSLVYRIIEGKLPPMPRDYSPELAELIRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KPYNYKSDVWALGCCVYEMATLKHAFNAKDMNSLVYRIIEGKLPPMPRDYSPELAELIRT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 MLSKRPEERPSVRSILRQPYIKRQISFFLEATKIKTSKNNIKNGDSQSKPFATVVSGEAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MLSKRPEERPSVRSILRQPYIKRQISFFLEATKIKTSKNNIKNGDSQSKPFATVVSGEAE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 SNHEVIHPQPLSSEGSQTYIMGEGKCLSQEKPRASGLLKSPASLKAHTCKQDLSNTTELA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SNHEVIHPQPLSSEGSQTYIMGEGKCLSQEKPRASGLLKSPASLKAHTCKQDLSNTTELA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 TISSVNIDILPAKGRDSVSDGFVQENQPRYLDASNELGGICSISQVEEEMLQDNTKSSAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TISSVNIDILPAKGRDSVSDGFVQENQPRYLDASNELGGICSISQVEEEMLQDNTKSSAQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 PENLIPMWSSDIVTGEKNEPVKPLQPLIKEQKPKDQDQVAGECIIEKQGRIHPDLQPHNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PENLIPMWSSDIVTGEKNEPVKPLQPLIKEQKPKDQDQVAGECIIEKQGRIHPDLQPHNS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 GSEPSLSRQRRQKRREQTEHRGEKRQVRRDLFAFQESPPRFLPSHPIVGKVDVTSTQKEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GSEPSLSRQRRQKRREQTEHRGEKRQVRRDLFAFQESPPRFLPSHPIVGKVDVTSTQKEA
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 ENQRRVVTGSVSSSRSSEMSSSKDRPLSARERRRLKQSQEEMSSSGPSVRKASLSVAGPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ENQRRVVTGSVSSSRSSEMSSSKDRPLSARERRRLKQSQEEMSSSGPSVRKASLSVAGPG
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 KPQEEDQPLPARRLSSDCSVTQERKQIHCLSEDELSSSTSSTDKSDGDYGEGKGQTNEIN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KPQEEDQPLPARRLSSDCSVTQERKQIHCLSEDELSSSTSSTDKSDGDYGEGKGQTNEIN
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 ALVQLMTQTLKLDSKESCEDVPVANPVSEFKLHRKYRDTLILHGKVAEEAEEIHFKELPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALVQLMTQTLKLDSKESCEDVPVANPVSEFKLHRKYRDTLILHGKVAEEAEEIHFKELPS
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE3 AIMPGSEKIRRLVEVLRTDVIRGLGVQLLEQVYDLLEEEDEFDREVRLREHMGEKYTTYS
:::::::::::::::::::::::::::::::::::::::::::::.
XP_016 AIMPGSEKIRRLVEVLRTDVIRGLGVQLLEQVYDLLEEEDEFDRELLPVFTPLMHSLPSG
730 740 750 760 770 780
790
pF1KE3 VKARQLKFFEENMNF
XP_016 LFAIFTLQSPELSLCLQHGDNAQVRKTDSQKDQVPVVLLHHFPV
790 800 810 820
>>XP_011532342 (OMIM: 601959) PREDICTED: serine/threonin (671 aa)
initn: 3015 init1: 3015 opt: 3047 Z-score: 1322.8 bits: 255.4 E(85289): 6.1e-67
Smith-Waterman score: 4007; 93.1% identity (93.1% similar) in 668 aa overlap (1-622:1-668)
10 20 30 40 50 60
pF1KE3 MPLAAYCYLRVVGKGSYGEVTLVKHRRDGKQYVIKKLNLRNASSRERRAAEQEAQLLSQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MPLAAYCYLRVVGKGSYGEVTLVKHRRDGKQYVIKKLNLRNASSRERRAAEQEAQLLSQL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 KHPNIVTYKESWEGGDGLLYIVMGFCEGGDLYRKLKEQKGQLLPENQVVEWFVQIAMALQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KHPNIVTYKESWEGGDGLLYIVMGFCEGGDLYRKLKEQKGQLLPENQVVEWFVQIAMALQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 YLHEKHILHRDLKTQNVFLTRTNIIKVGDLGIARVLENHCDMASTLIGTPYYMSPELFSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YLHEKHILHRDLKTQNVFLTRTNIIKVGDLGIARVLENHCDMASTLIGTPYYMSPELFSN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 KPYNYKSDVWALGCCVYEMATLKHAFNAKDMNSLVYRIIEGKLPPMPRDYSPELAELIRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KPYNYKSDVWALGCCVYEMATLKHAFNAKDMNSLVYRIIEGKLPPMPRDYSPELAELIRT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 MLSKRPEERPSVRSILRQPYIKRQISFFLEATKIKTSKNNIKNGDSQSKPFATVVSGEAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MLSKRPEERPSVRSILRQPYIKRQISFFLEATKIKTSKNNIKNGDSQSKPFATVVSGEAE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 SNHEVIHPQPLSSEGSQTYIMGEGKCLSQEKPRASGLLKSPASLKAHTCKQDLSNTTELA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SNHEVIHPQPLSSEGSQTYIMGEGKCLSQEKPRASGLLKSPASLKAHTCKQDLSNTTELA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 TISSVNIDILPAKGRDSVSDGFVQENQPRYLDASNELGGICSISQVEEEMLQDNTKSSAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TISSVNIDILPAKGRDSVSDGFVQENQPRYLDASNELGGICSISQVEEEMLQDNTKSSAQ
370 380 390 400 410 420
430 440 450
pF1KE3 PENLIPMWSSDIVTGEKNEPVKPLQPLIKEQKPKDQ------------------------
::::::::::::::::::::::::::::::::::::
XP_011 PENLIPMWSSDIVTGEKNEPVKPLQPLIKEQKPKDQSLALSPKLECSGTILAHSNLRLLG
430 440 450 460 470 480
460 470 480 490
pF1KE3 ----------------------DQVAGECIIEKQGRIHPDLQPHNSGSEPSLSRQRRQKR
::::::::::::::::::::::::::::::::::::::
XP_011 SSDSPASASRVAGITGVCHHAQDQVAGECIIEKQGRIHPDLQPHNSGSEPSLSRQRRQKR
490 500 510 520 530 540
500 510 520 530 540 550
pF1KE3 REQTEHRGEKRQVRRDLFAFQESPPRFLPSHPIVGKVDVTSTQKEAENQRRVVTGSVSSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 REQTEHRGEKRQVRRDLFAFQESPPRFLPSHPIVGKVDVTSTQKEAENQRRVVTGSVSSS
550 560 570 580 590 600
560 570 580 590 600 610
pF1KE3 RSSEMSSSKDRPLSARERRRLKQSQEEMSSSGPSVRKASLSVAGPGKPQEEDQPLPARRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RSSEMSSSKDRPLSARERRRLKQSQEEMSSSGPSVRKASLSVAGPGKPQEEDQPLPARRL
610 620 630 640 650 660
620 630 640 650 660 670
pF1KE3 SSDCSVTQERKQIHCLSEDELSSSTSSTDKSDGDYGEGKGQTNEINALVQLMTQTLKLDS
::::::::
XP_011 SSDCSVTQVIL
670
>>NP_003148 (OMIM: 601959) serine/threonine-protein kina (841 aa)
initn: 3015 init1: 3015 opt: 3047 Z-score: 1321.9 bits: 255.5 E(85289): 6.8e-67
Smith-Waterman score: 5025; 94.4% identity (94.4% similar) in 827 aa overlap (1-781:1-827)
10 20 30 40 50 60
pF1KE3 MPLAAYCYLRVVGKGSYGEVTLVKHRRDGKQYVIKKLNLRNASSRERRAAEQEAQLLSQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MPLAAYCYLRVVGKGSYGEVTLVKHRRDGKQYVIKKLNLRNASSRERRAAEQEAQLLSQL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 KHPNIVTYKESWEGGDGLLYIVMGFCEGGDLYRKLKEQKGQLLPENQVVEWFVQIAMALQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 KHPNIVTYKESWEGGDGLLYIVMGFCEGGDLYRKLKEQKGQLLPENQVVEWFVQIAMALQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 YLHEKHILHRDLKTQNVFLTRTNIIKVGDLGIARVLENHCDMASTLIGTPYYMSPELFSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 YLHEKHILHRDLKTQNVFLTRTNIIKVGDLGIARVLENHCDMASTLIGTPYYMSPELFSN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 KPYNYKSDVWALGCCVYEMATLKHAFNAKDMNSLVYRIIEGKLPPMPRDYSPELAELIRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 KPYNYKSDVWALGCCVYEMATLKHAFNAKDMNSLVYRIIEGKLPPMPRDYSPELAELIRT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 MLSKRPEERPSVRSILRQPYIKRQISFFLEATKIKTSKNNIKNGDSQSKPFATVVSGEAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MLSKRPEERPSVRSILRQPYIKRQISFFLEATKIKTSKNNIKNGDSQSKPFATVVSGEAE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 SNHEVIHPQPLSSEGSQTYIMGEGKCLSQEKPRASGLLKSPASLKAHTCKQDLSNTTELA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 SNHEVIHPQPLSSEGSQTYIMGEGKCLSQEKPRASGLLKSPASLKAHTCKQDLSNTTELA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 TISSVNIDILPAKGRDSVSDGFVQENQPRYLDASNELGGICSISQVEEEMLQDNTKSSAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 TISSVNIDILPAKGRDSVSDGFVQENQPRYLDASNELGGICSISQVEEEMLQDNTKSSAQ
370 380 390 400 410 420
430 440 450
pF1KE3 PENLIPMWSSDIVTGEKNEPVKPLQPLIKEQKPKDQ------------------------
::::::::::::::::::::::::::::::::::::
NP_003 PENLIPMWSSDIVTGEKNEPVKPLQPLIKEQKPKDQSLALSPKLECSGTILAHSNLRLLG
430 440 450 460 470 480
460 470 480 490
pF1KE3 ----------------------DQVAGECIIEKQGRIHPDLQPHNSGSEPSLSRQRRQKR
::::::::::::::::::::::::::::::::::::::
NP_003 SSDSPASASRVAGITGVCHHAQDQVAGECIIEKQGRIHPDLQPHNSGSEPSLSRQRRQKR
490 500 510 520 530 540
500 510 520 530 540 550
pF1KE3 REQTEHRGEKRQVRRDLFAFQESPPRFLPSHPIVGKVDVTSTQKEAENQRRVVTGSVSSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 REQTEHRGEKRQVRRDLFAFQESPPRFLPSHPIVGKVDVTSTQKEAENQRRVVTGSVSSS
550 560 570 580 590 600
560 570 580 590 600 610
pF1KE3 RSSEMSSSKDRPLSARERRRLKQSQEEMSSSGPSVRKASLSVAGPGKPQEEDQPLPARRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 RSSEMSSSKDRPLSARERRRLKQSQEEMSSSGPSVRKASLSVAGPGKPQEEDQPLPARRL
610 620 630 640 650 660
620 630 640 650 660 670
pF1KE3 SSDCSVTQERKQIHCLSEDELSSSTSSTDKSDGDYGEGKGQTNEINALVQLMTQTLKLDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 SSDCSVTQERKQIHCLSEDELSSSTSSTDKSDGDYGEGKGQTNEINALVQLMTQTLKLDS
670 680 690 700 710 720
680 690 700 710 720 730
pF1KE3 KESCEDVPVANPVSEFKLHRKYRDTLILHGKVAEEAEEIHFKELPSAIMPGSEKIRRLVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 KESCEDVPVANPVSEFKLHRKYRDTLILHGKVAEEAEEIHFKELPSAIMPGSEKIRRLVE
730 740 750 760 770 780
740 750 760 770 780 790
pF1KE3 VLRTDVIRGLGVQLLEQVYDLLEEEDEFDREVRLREHMGEKYTTYSVKARQLKFFEENMN
:::::::::::::::::::::::::::::::::::::::::::::::
NP_003 VLRTDVIRGLGVQLLEQVYDLLEEEDEFDREVRLREHMGEKYTTYSVKARQLKFFEENMN
790 800 810 820 830 840
pF1KE3 F
NP_003 F
>>XP_011532341 (OMIM: 601959) PREDICTED: serine/threonin (842 aa)
initn: 3015 init1: 3015 opt: 3047 Z-score: 1321.9 bits: 255.5 E(85289): 6.8e-67
Smith-Waterman score: 4922; 94.3% identity (94.3% similar) in 811 aa overlap (1-765:1-811)
10 20 30 40 50 60
pF1KE3 MPLAAYCYLRVVGKGSYGEVTLVKHRRDGKQYVIKKLNLRNASSRERRAAEQEAQLLSQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MPLAAYCYLRVVGKGSYGEVTLVKHRRDGKQYVIKKLNLRNASSRERRAAEQEAQLLSQL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 KHPNIVTYKESWEGGDGLLYIVMGFCEGGDLYRKLKEQKGQLLPENQVVEWFVQIAMALQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KHPNIVTYKESWEGGDGLLYIVMGFCEGGDLYRKLKEQKGQLLPENQVVEWFVQIAMALQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 YLHEKHILHRDLKTQNVFLTRTNIIKVGDLGIARVLENHCDMASTLIGTPYYMSPELFSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YLHEKHILHRDLKTQNVFLTRTNIIKVGDLGIARVLENHCDMASTLIGTPYYMSPELFSN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 KPYNYKSDVWALGCCVYEMATLKHAFNAKDMNSLVYRIIEGKLPPMPRDYSPELAELIRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KPYNYKSDVWALGCCVYEMATLKHAFNAKDMNSLVYRIIEGKLPPMPRDYSPELAELIRT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 MLSKRPEERPSVRSILRQPYIKRQISFFLEATKIKTSKNNIKNGDSQSKPFATVVSGEAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MLSKRPEERPSVRSILRQPYIKRQISFFLEATKIKTSKNNIKNGDSQSKPFATVVSGEAE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 SNHEVIHPQPLSSEGSQTYIMGEGKCLSQEKPRASGLLKSPASLKAHTCKQDLSNTTELA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SNHEVIHPQPLSSEGSQTYIMGEGKCLSQEKPRASGLLKSPASLKAHTCKQDLSNTTELA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 TISSVNIDILPAKGRDSVSDGFVQENQPRYLDASNELGGICSISQVEEEMLQDNTKSSAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TISSVNIDILPAKGRDSVSDGFVQENQPRYLDASNELGGICSISQVEEEMLQDNTKSSAQ
370 380 390 400 410 420
430 440 450
pF1KE3 PENLIPMWSSDIVTGEKNEPVKPLQPLIKEQKPKDQ------------------------
::::::::::::::::::::::::::::::::::::
XP_011 PENLIPMWSSDIVTGEKNEPVKPLQPLIKEQKPKDQSLALSPKLECSGTILAHSNLRLLG
430 440 450 460 470 480
460 470 480 490
pF1KE3 ----------------------DQVAGECIIEKQGRIHPDLQPHNSGSEPSLSRQRRQKR
::::::::::::::::::::::::::::::::::::::
XP_011 SSDSPASASRVAGITGVCHHAQDQVAGECIIEKQGRIHPDLQPHNSGSEPSLSRQRRQKR
490 500 510 520 530 540
500 510 520 530 540 550
pF1KE3 REQTEHRGEKRQVRRDLFAFQESPPRFLPSHPIVGKVDVTSTQKEAENQRRVVTGSVSSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 REQTEHRGEKRQVRRDLFAFQESPPRFLPSHPIVGKVDVTSTQKEAENQRRVVTGSVSSS
550 560 570 580 590 600
560 570 580 590 600 610
pF1KE3 RSSEMSSSKDRPLSARERRRLKQSQEEMSSSGPSVRKASLSVAGPGKPQEEDQPLPARRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RSSEMSSSKDRPLSARERRRLKQSQEEMSSSGPSVRKASLSVAGPGKPQEEDQPLPARRL
610 620 630 640 650 660
620 630 640 650 660 670
pF1KE3 SSDCSVTQERKQIHCLSEDELSSSTSSTDKSDGDYGEGKGQTNEINALVQLMTQTLKLDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSDCSVTQERKQIHCLSEDELSSSTSSTDKSDGDYGEGKGQTNEINALVQLMTQTLKLDS
670 680 690 700 710 720
680 690 700 710 720 730
pF1KE3 KESCEDVPVANPVSEFKLHRKYRDTLILHGKVAEEAEEIHFKELPSAIMPGSEKIRRLVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KESCEDVPVANPVSEFKLHRKYRDTLILHGKVAEEAEEIHFKELPSAIMPGSEKIRRLVE
730 740 750 760 770 780
740 750 760 770 780 790
pF1KE3 VLRTDVIRGLGVQLLEQVYDLLEEEDEFDREVRLREHMGEKYTTYSVKARQLKFFEENMN
:::::::::::::::::::::::::::::::
XP_011 VLRTDVIRGLGVQLLEQVYDLLEEEDEFDRECPCLAPAPGHCRQPHKMNQELPLPPQLSG
790 800 810 820 830 840
pF1KE3 F
XP_011 KV
>>XP_016862574 (OMIM: 601959) PREDICTED: serine/threonin (870 aa)
initn: 5018 init1: 3015 opt: 3047 Z-score: 1321.8 bits: 255.6 E(85289): 6.9e-67
Smith-Waterman score: 4923; 94.2% identity (94.3% similar) in 812 aa overlap (1-766:1-812)
10 20 30 40 50 60
pF1KE3 MPLAAYCYLRVVGKGSYGEVTLVKHRRDGKQYVIKKLNLRNASSRERRAAEQEAQLLSQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MPLAAYCYLRVVGKGSYGEVTLVKHRRDGKQYVIKKLNLRNASSRERRAAEQEAQLLSQL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 KHPNIVTYKESWEGGDGLLYIVMGFCEGGDLYRKLKEQKGQLLPENQVVEWFVQIAMALQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KHPNIVTYKESWEGGDGLLYIVMGFCEGGDLYRKLKEQKGQLLPENQVVEWFVQIAMALQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 YLHEKHILHRDLKTQNVFLTRTNIIKVGDLGIARVLENHCDMASTLIGTPYYMSPELFSN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YLHEKHILHRDLKTQNVFLTRTNIIKVGDLGIARVLENHCDMASTLIGTPYYMSPELFSN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 KPYNYKSDVWALGCCVYEMATLKHAFNAKDMNSLVYRIIEGKLPPMPRDYSPELAELIRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KPYNYKSDVWALGCCVYEMATLKHAFNAKDMNSLVYRIIEGKLPPMPRDYSPELAELIRT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 MLSKRPEERPSVRSILRQPYIKRQISFFLEATKIKTSKNNIKNGDSQSKPFATVVSGEAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MLSKRPEERPSVRSILRQPYIKRQISFFLEATKIKTSKNNIKNGDSQSKPFATVVSGEAE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 SNHEVIHPQPLSSEGSQTYIMGEGKCLSQEKPRASGLLKSPASLKAHTCKQDLSNTTELA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SNHEVIHPQPLSSEGSQTYIMGEGKCLSQEKPRASGLLKSPASLKAHTCKQDLSNTTELA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 TISSVNIDILPAKGRDSVSDGFVQENQPRYLDASNELGGICSISQVEEEMLQDNTKSSAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TISSVNIDILPAKGRDSVSDGFVQENQPRYLDASNELGGICSISQVEEEMLQDNTKSSAQ
370 380 390 400 410 420
430 440 450
pF1KE3 PENLIPMWSSDIVTGEKNEPVKPLQPLIKEQKPKDQ------------------------
::::::::::::::::::::::::::::::::::::
XP_016 PENLIPMWSSDIVTGEKNEPVKPLQPLIKEQKPKDQSLALSPKLECSGTILAHSNLRLLG
430 440 450 460 470 480
460 470 480 490
pF1KE3 ----------------------DQVAGECIIEKQGRIHPDLQPHNSGSEPSLSRQRRQKR
::::::::::::::::::::::::::::::::::::::
XP_016 SSDSPASASRVAGITGVCHHAQDQVAGECIIEKQGRIHPDLQPHNSGSEPSLSRQRRQKR
490 500 510 520 530 540
500 510 520 530 540 550
pF1KE3 REQTEHRGEKRQVRRDLFAFQESPPRFLPSHPIVGKVDVTSTQKEAENQRRVVTGSVSSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 REQTEHRGEKRQVRRDLFAFQESPPRFLPSHPIVGKVDVTSTQKEAENQRRVVTGSVSSS
550 560 570 580 590 600
560 570 580 590 600 610
pF1KE3 RSSEMSSSKDRPLSARERRRLKQSQEEMSSSGPSVRKASLSVAGPGKPQEEDQPLPARRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RSSEMSSSKDRPLSARERRRLKQSQEEMSSSGPSVRKASLSVAGPGKPQEEDQPLPARRL
610 620 630 640 650 660
620 630 640 650 660 670
pF1KE3 SSDCSVTQERKQIHCLSEDELSSSTSSTDKSDGDYGEGKGQTNEINALVQLMTQTLKLDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SSDCSVTQERKQIHCLSEDELSSSTSSTDKSDGDYGEGKGQTNEINALVQLMTQTLKLDS
670 680 690 700 710 720
680 690 700 710 720 730
pF1KE3 KESCEDVPVANPVSEFKLHRKYRDTLILHGKVAEEAEEIHFKELPSAIMPGSEKIRRLVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KESCEDVPVANPVSEFKLHRKYRDTLILHGKVAEEAEEIHFKELPSAIMPGSEKIRRLVE
730 740 750 760 770 780
740 750 760 770 780 790
pF1KE3 VLRTDVIRGLGVQLLEQVYDLLEEEDEFDREVRLREHMGEKYTTYSVKARQLKFFEENMN
:::::::::::::::::::::::::::::::.
XP_016 VLRTDVIRGLGVQLLEQVYDLLEEEDEFDRELLPVFTPLMHSLPSGLFAIFTLQSPELSL
790 800 810 820 830 840
pF1KE3 F
XP_016 CLQHGDNAQVRKTDSQKDQVPVVLLHHFPV
850 860 870
>>NP_001180462 (OMIM: 601959) serine/threonine-protein k (752 aa)
initn: 2421 init1: 2224 opt: 2256 Z-score: 987.0 bits: 193.4 E(85289): 3.1e-48
Smith-Waterman score: 4250; 83.7% identity (83.7% similar) in 827 aa overlap (1-781:1-738)
10 20 30 40 50 60
pF1KE3 MPLAAYCYLRVVGKGSYGEVTLVKHRRDGKQYVIKKLNLRNASSRERRAAEQEAQLLSQL
::::::::::::::::::::::::::::::::
NP_001 MPLAAYCYLRVVGKGSYGEVTLVKHRRDGKQY----------------------------
10 20 30
70 80 90 100 110 120
pF1KE3 KHPNIVTYKESWEGGDGLLYIVMGFCEGGDLYRKLKEQKGQLLPENQVVEWFVQIAMALQ
NP_001 ------------------------------------------------------------
130 140 150 160 170 180
pF1KE3 YLHEKHILHRDLKTQNVFLTRTNIIKVGDLGIARVLENHCDMASTLIGTPYYMSPELFSN
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 -LHEKHILHRDLKTQNVFLTRTNIIKVGDLGIARVLENHCDMASTLIGTPYYMSPELFSN
40 50 60 70 80 90
190 200 210 220 230 240
pF1KE3 KPYNYKSDVWALGCCVYEMATLKHAFNAKDMNSLVYRIIEGKLPPMPRDYSPELAELIRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KPYNYKSDVWALGCCVYEMATLKHAFNAKDMNSLVYRIIEGKLPPMPRDYSPELAELIRT
100 110 120 130 140 150
250 260 270 280 290 300
pF1KE3 MLSKRPEERPSVRSILRQPYIKRQISFFLEATKIKTSKNNIKNGDSQSKPFATVVSGEAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MLSKRPEERPSVRSILRQPYIKRQISFFLEATKIKTSKNNIKNGDSQSKPFATVVSGEAE
160 170 180 190 200 210
310 320 330 340 350 360
pF1KE3 SNHEVIHPQPLSSEGSQTYIMGEGKCLSQEKPRASGLLKSPASLKAHTCKQDLSNTTELA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SNHEVIHPQPLSSEGSQTYIMGEGKCLSQEKPRASGLLKSPASLKAHTCKQDLSNTTELA
220 230 240 250 260 270
370 380 390 400 410 420
pF1KE3 TISSVNIDILPAKGRDSVSDGFVQENQPRYLDASNELGGICSISQVEEEMLQDNTKSSAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TISSVNIDILPAKGRDSVSDGFVQENQPRYLDASNELGGICSISQVEEEMLQDNTKSSAQ
280 290 300 310 320 330
430 440 450
pF1KE3 PENLIPMWSSDIVTGEKNEPVKPLQPLIKEQKPKDQ------------------------
::::::::::::::::::::::::::::::::::::
NP_001 PENLIPMWSSDIVTGEKNEPVKPLQPLIKEQKPKDQSLALSPKLECSGTILAHSNLRLLG
340 350 360 370 380 390
460 470 480 490
pF1KE3 ----------------------DQVAGECIIEKQGRIHPDLQPHNSGSEPSLSRQRRQKR
::::::::::::::::::::::::::::::::::::::
NP_001 SSDSPASASRVAGITGVCHHAQDQVAGECIIEKQGRIHPDLQPHNSGSEPSLSRQRRQKR
400 410 420 430 440 450
500 510 520 530 540 550
pF1KE3 REQTEHRGEKRQVRRDLFAFQESPPRFLPSHPIVGKVDVTSTQKEAENQRRVVTGSVSSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 REQTEHRGEKRQVRRDLFAFQESPPRFLPSHPIVGKVDVTSTQKEAENQRRVVTGSVSSS
460 470 480 490 500 510
560 570 580 590 600 610
pF1KE3 RSSEMSSSKDRPLSARERRRLKQSQEEMSSSGPSVRKASLSVAGPGKPQEEDQPLPARRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RSSEMSSSKDRPLSARERRRLKQSQEEMSSSGPSVRKASLSVAGPGKPQEEDQPLPARRL
520 530 540 550 560 570
620 630 640 650 660 670
pF1KE3 SSDCSVTQERKQIHCLSEDELSSSTSSTDKSDGDYGEGKGQTNEINALVQLMTQTLKLDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSDCSVTQERKQIHCLSEDELSSSTSSTDKSDGDYGEGKGQTNEINALVQLMTQTLKLDS
580 590 600 610 620 630
680 690 700 710 720 730
pF1KE3 KESCEDVPVANPVSEFKLHRKYRDTLILHGKVAEEAEEIHFKELPSAIMPGSEKIRRLVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KESCEDVPVANPVSEFKLHRKYRDTLILHGKVAEEAEEIHFKELPSAIMPGSEKIRRLVE
640 650 660 670 680 690
740 750 760 770 780 790
pF1KE3 VLRTDVIRGLGVQLLEQVYDLLEEEDEFDREVRLREHMGEKYTTYSVKARQLKFFEENMN
:::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLRTDVIRGLGVQLLEQVYDLLEEEDEFDREVRLREHMGEKYTTYSVKARQLKFFEENMN
700 710 720 730 740 750
pF1KE3 F
NP_001 F
>>XP_011530306 (OMIM: 263520,604588) PREDICTED: serine/t (1214 aa)
initn: 797 init1: 756 opt: 988 Z-score: 447.5 bits: 94.3 E(85289): 3.5e-18
Smith-Waterman score: 1000; 29.8% identity (61.3% similar) in 732 aa overlap (3-697:1-707)
10 20 30 40 50 60
pF1KE3 MPLAAYCYLRVVGKGSYGEVTLVKHRRDGKQYVIKKLNLRNASSRERRAAEQEAQLLSQL
. : :. .:.::.:.. ::: .::.:::::..:. ::.::. ...:. .:...
XP_011 MEKYVRLQKIGEGSFGKAILVKSTEDGRQYVIKEINISRMSSKEREESRREVAVLANM
10 20 30 40 50
70 80 90 100 110 120
pF1KE3 KHPNIVTYKESWEGGDGLLYIVMGFCEGGDLYRKLKEQKGQLLPENQVVEWFVQIAMALQ
:::::: :.::.: .: ::::: .::::::..... ::: :. :.:...::::: .::.
XP_011 KHPNIVQYRESFEE-NGSLYIVMDYCEGGDLFKRINAQKGVLFQEDQILDWFVQICLALK
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE3 YLHEKHILHRDLKTQNVFLTRTNIIKVGDLGIARVLENHCDMASTLIGTPYYMSPELFSN
..:...:::::.:.::.:::. . ...::.::::::.. ..: : ::::::.:::. :
XP_011 HVHDRKILHRDIKSQNIFLTKDGTVQLGDFGIARVLNSTVELARTCIGTPYYLSPEICEN
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE3 KPYNYKSDVWALGCCVYEMATLKHAFNAKDMNSLVYRIIEGKLPPMPRDYSPELAELIRT
:::: :::.::::: .::. ::::::.: .:..:: .:: :..::. :: .: :.
XP_011 KPYNNKSDIWALGCVLYELCTLKHAFEAGSMKNLVLKIISGSFPPVSLHYSYDLRSLVSQ
180 190 200 210 220 230
250 260 270 280 290
pF1KE3 MLSKRPEERPSVRSILRQPYIKRQISFFLEATKIKTS---KNNIKNGDSQSKPFATVVSG
.... :..:::: :::.. .: ..: :: : :. : : :: : .::
XP_011 LFKRNPRDRPSVNSILEKGFIAKRIEKFLSPQLIAEEFCLKTFSKFG-SQPIPAKRPASG
240 250 260 270 280 290
300 310 320 330 340
pF1KE3 EAESNHEVIHP-----QPLSSEGSQTYIMGEG-KCLSQEKP--RASGLLKSPASLKAHTC
. : . : .: .. : : : : ..:: . . ..: . ...:
XP_011 Q---NSISVMPAQKITKPAAKYGIPLAYKKYGDKKLHEKKPLQKHKQAHQTPEK-RVNTG
300 310 320 330 340 350
350 360 370 380 390 400
pF1KE3 KQDLSNTTELATISSVNIDILPAKGRDSVSDGFVQENQPRYLDASNELGGICSISQVEEE
.. . . : : ... : .:.. . . :.. : .: . :....:.
XP_011 EERRKISEEAARKRRLEFIEKEKKQKDQIISLMKAEQMKR-----QEKERLERINRAREQ
360 370 380 390 400
410 420 430 440 450 460
pF1KE3 MLQDNTKSSAQPENLIPMWSSDIVTGEKN-------EPVKPLQPLIKEQKPKDQDQVAGE
.. ..... : :. .: . . .. : . . ...:. .:.. .
XP_011 GWRNVLSAGGSGEVKAPFLGSGGTIAPSSFSSRGQYEHYHAIFDQMQQQRAEDNEAKWKR
410 420 430 440 450 460
470 480 490 500 510
pF1KE3 CIIEKQGRIHPDLQPHNSGSEPSLSRQRR-QKRRE--QTEHRGEK--------RQVRRDL
: :: :. : . . : . . .. :..:: :.. :.: ::.: .
XP_011 ---EIYGRGLPERQKGQLAVERAKQVEEFLQRKREAMQNKARAEGHMVYLARLRQIRLQN
470 480 490 500 510 520
520 530 540 550 560
pF1KE3 FAF-QESPPRFLPSHPIVGKVDVTSTQKEAENQRRVVTG--SVSSSRSSEMSSSKDRPLS
: :. .. . ... . ..::. .:. . . . ...:.. .. . .: .
XP_011 FNERQQIKAKLRGEKKEANHSEGQEGSEEADMRRKKIESLKAHANARAAVLKEQLERKRK
530 540 550 560 570 580
570 580 590 600 610 620
pF1KE3 ARERRRLKQSQEEMSSSGPSVRKASLSVAGPGKPQEEDQPLPARR-LSSDCSVTQERKQI
.:. : .:.. ..: :.....: : :.: :... . : :::. :..
XP_011 EAYEREKKVWEEHLVAKG--VKSSDVS---PPLGQHETGGSPSKQQMRSVISVTSALKEV
590 600 610 620 630
630 640 650 660 670 680
pF1KE3 HCLSEDELSSSTSSTDKSDGDYGEGKGQTNEINALVQLMTQTLKLD----SKESCEDVPV
..:: ..: ... .. . .. . ... ....:: . .:.. :.
XP_011 G------VDSSLTDTRETSEEMQKTNNAISSKREILRRLNENLKAQEDEKGKQNLSDTFE
640 650 660 670 680 690
690 700 710 720 730 740
pF1KE3 ANPVSEFKLHRKYRDTLILHGKVAEEAEEIHFKELPSAIMPGSEKIRRLVEVLRTDVIRG
: . : :.: .
XP_011 INVHEDAKEHEKEKSVSSDRKKWEAGGQLVIPLDELTLDTSFSTTERHTVGEVIKLGPNG
700 710 720 730 740 750
>>NP_001186329 (OMIM: 263520,604588) serine/threonine-pr (1214 aa)
initn: 797 init1: 756 opt: 988 Z-score: 447.5 bits: 94.3 E(85289): 3.5e-18
Smith-Waterman score: 1000; 29.8% identity (61.3% similar) in 732 aa overlap (3-697:1-707)
10 20 30 40 50 60
pF1KE3 MPLAAYCYLRVVGKGSYGEVTLVKHRRDGKQYVIKKLNLRNASSRERRAAEQEAQLLSQL
. : :. .:.::.:.. ::: .::.:::::..:. ::.::. ...:. .:...
NP_001 MEKYVRLQKIGEGSFGKAILVKSTEDGRQYVIKEINISRMSSKEREESRREVAVLANM
10 20 30 40 50
70 80 90 100 110 120
pF1KE3 KHPNIVTYKESWEGGDGLLYIVMGFCEGGDLYRKLKEQKGQLLPENQVVEWFVQIAMALQ
:::::: :.::.: .: ::::: .::::::..... ::: :. :.:...::::: .::.
NP_001 KHPNIVQYRESFEE-NGSLYIVMDYCEGGDLFKRINAQKGVLFQEDQILDWFVQICLALK
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE3 YLHEKHILHRDLKTQNVFLTRTNIIKVGDLGIARVLENHCDMASTLIGTPYYMSPELFSN
..:...:::::.:.::.:::. . ...::.::::::.. ..: : ::::::.:::. :
NP_001 HVHDRKILHRDIKSQNIFLTKDGTVQLGDFGIARVLNSTVELARTCIGTPYYLSPEICEN
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE3 KPYNYKSDVWALGCCVYEMATLKHAFNAKDMNSLVYRIIEGKLPPMPRDYSPELAELIRT
:::: :::.::::: .::. ::::::.: .:..:: .:: :..::. :: .: :.
NP_001 KPYNNKSDIWALGCVLYELCTLKHAFEAGSMKNLVLKIISGSFPPVSLHYSYDLRSLVSQ
180 190 200 210 220 230
250 260 270 280 290
pF1KE3 MLSKRPEERPSVRSILRQPYIKRQISFFLEATKIKTS---KNNIKNGDSQSKPFATVVSG
.... :..:::: :::.. .: ..: :: : :. : : :: : .::
NP_001 LFKRNPRDRPSVNSILEKGFIAKRIEKFLSPQLIAEEFCLKTFSKFG-SQPIPAKRPASG
240 250 260 270 280 290
300 310 320 330 340
pF1KE3 EAESNHEVIHP-----QPLSSEGSQTYIMGEG-KCLSQEKP--RASGLLKSPASLKAHTC
. : . : .: .. : : : : ..:: . . ..: . ...:
NP_001 Q---NSISVMPAQKITKPAAKYGIPLAYKKYGDKKLHEKKPLQKHKQAHQTPEK-RVNTG
300 310 320 330 340 350
350 360 370 380 390 400
pF1KE3 KQDLSNTTELATISSVNIDILPAKGRDSVSDGFVQENQPRYLDASNELGGICSISQVEEE
.. . . : : ... : .:.. . . :.. : .: . :....:.
NP_001 EERRKISEEAARKRRLEFIEKEKKQKDQIISLMKAEQMKR-----QEKERLERINRAREQ
360 370 380 390 400
410 420 430 440 450 460
pF1KE3 MLQDNTKSSAQPENLIPMWSSDIVTGEKN-------EPVKPLQPLIKEQKPKDQDQVAGE
.. ..... : :. .: . . .. : . . ...:. .:.. .
NP_001 GWRNVLSAGGSGEVKAPFLGSGGTIAPSSFSSRGQYEHYHAIFDQMQQQRAEDNEAKWKR
410 420 430 440 450 460
470 480 490 500 510
pF1KE3 CIIEKQGRIHPDLQPHNSGSEPSLSRQRR-QKRRE--QTEHRGEK--------RQVRRDL
: :: :. : . . : . . .. :..:: :.. :.: ::.: .
NP_001 ---EIYGRGLPERQKGQLAVERAKQVEEFLQRKREAMQNKARAEGHMVYLARLRQIRLQN
470 480 490 500 510 520
520 530 540 550 560
pF1KE3 FAF-QESPPRFLPSHPIVGKVDVTSTQKEAENQRRVVTG--SVSSSRSSEMSSSKDRPLS
: :. .. . ... . ..::. .:. . . . ...:.. .. . .: .
NP_001 FNERQQIKAKLRGEKKEANHSEGQEGSEEADMRRKKIESLKAHANARAAVLKEQLERKRK
530 540 550 560 570 580
570 580 590 600 610 620
pF1KE3 ARERRRLKQSQEEMSSSGPSVRKASLSVAGPGKPQEEDQPLPARR-LSSDCSVTQERKQI
.:. : .:.. ..: :.....: : :.: :... . : :::. :..
NP_001 EAYEREKKVWEEHLVAKG--VKSSDVS---PPLGQHETGGSPSKQQMRSVISVTSALKEV
590 600 610 620 630
630 640 650 660 670 680
pF1KE3 HCLSEDELSSSTSSTDKSDGDYGEGKGQTNEINALVQLMTQTLKLD----SKESCEDVPV
..:: ..: ... .. . .. . ... ....:: . .:.. :.
NP_001 G------VDSSLTDTRETSEEMQKTNNAISSKREILRRLNENLKAQEDEKGKQNLSDTFE
640 650 660 670 680 690
690 700 710 720 730 740
pF1KE3 ANPVSEFKLHRKYRDTLILHGKVAEEAEEIHFKELPSAIMPGSEKIRRLVEVLRTDVIRG
: . : :.: .
NP_001 INVHEDAKEHEKEKSVSSDRKKWEAGGQLVIPLDELTLDTSFSTTERHTVGEVIKLGPNG
700 710 720 730 740 750
>>XP_011530307 (OMIM: 263520,604588) PREDICTED: serine/t (715 aa)
initn: 834 init1: 756 opt: 979 Z-score: 445.7 bits: 93.2 E(85289): 4.3e-18
Smith-Waterman score: 1002; 29.5% identity (60.3% similar) in 760 aa overlap (3-746:1-713)
10 20 30 40 50 60
pF1KE3 MPLAAYCYLRVVGKGSYGEVTLVKHRRDGKQYVIKKLNLRNASSRERRAAEQEAQLLSQL
. : :. .:.::.:.. ::: .::.:::::..:. ::.::. ...:. .:...
XP_011 MEKYVRLQKIGEGSFGKAILVKSTEDGRQYVIKEINISRMSSKEREESRREVAVLANM
10 20 30 40 50
70 80 90 100 110 120
pF1KE3 KHPNIVTYKESWEGGDGLLYIVMGFCEGGDLYRKLKEQKGQLLPENQVVEWFVQIAMALQ
:::::: :.::.: .: ::::: .::::::..... ::: :. :.:...::::: .::.
XP_011 KHPNIVQYRESFEE-NGSLYIVMDYCEGGDLFKRINAQKGVLFQEDQILDWFVQICLALK
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE3 YLHEKHILHRDLKTQNVFLTRTNIIKVGDLGIARVLENHCDMASTLIGTPYYMSPELFSN
..:...:::::.:.::.:::. . ...::.::::::.. ..: : ::::::.:::. :
XP_011 HVHDRKILHRDIKSQNIFLTKDGTVQLGDFGIARVLNSTVELARTCIGTPYYLSPEICEN
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE3 KPYNYKSDVWALGCCVYEMATLKHAFNAKDMNSLVYRIIEGKLPPMPRDYSPELAELIRT
:::: :::.::::: .::. ::::::.: .:..:: .:: :..::. :: .: :.
XP_011 KPYNNKSDIWALGCVLYELCTLKHAFEAGSMKNLVLKIISGSFPPVSLHYSYDLRSLVSQ
180 190 200 210 220 230
250 260 270 280 290
pF1KE3 MLSKRPEERPSVRSILRQPYIKRQISFFLEATKIKTS---KNNIKNGDSQSKPFATVVSG
.... :..:::: :::.. .: ..: :: : :. : : :: : .::
XP_011 LFKRNPRDRPSVNSILEKGFIAKRIEKFLSPQLIAEEFCLKTFSKFG-SQPIPAKRPASG
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE3 EAESNHEVIHPQPLSSEGSQTYIMGEGKCLSQEKPRASGLLKSPASLKAHTCKQDLSNTT
. .. :. : ... ... : : ...: . . :.. .:: . ::
XP_011 Q--NSISVMPAQKITKPAAKYGIPLAYKKYGDKKLHEKKPLQKHK--QAHQTPEKRVNTG
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE3 ELATISSVNIDILPAKGRDSVSDGFVQENQPRYLDASNELGGICSISQVEEEMLQDNTKS
: .:. :. : :. :.. . : : .... :.: :. ...
XP_011 E----ERRKISEEAARKR---RLEFI-EKEKKQKDQIISLMKAEQMKRQEKERLERINRA
360 370 380 390 400
420 430 440 450 460 470
pF1KE3 SAQPENLIPMWSSDIVTGEKNEPVKPLQPLIKEQKPKDQDQVAGECIIEKQGRIHPDLQP
: : . . .: ..: :: :.. .. ... :. : ..:
XP_011 REQG------WRNVLSAGGSGE-VKA--PFLGSGGTIAPSSFSSRGQYEHYHAIFDQMQQ
410 420 430 440 450
480 490 500 510 520 530
pF1KE3 HNSGSEPSLSRQRRQKRREQTEHRGEKRQVRRDLFAFQESPPRFLPSHPIVGKV--DVTS
. .: . .. .:. . .:: :: : . . . .:. . :. . .
XP_011 QR--AEDNEAKWKREIYGRGLPERGILPGVRPG-FPYGAAGHHHFPDADDIRKTLKRLKA
460 470 480 490 500 510
540 550 560 570 580 590
pF1KE3 TQKEAENQRRVVTGSVSSSRSSEMSSSKDRPLSARERRRLKQSQEEMSSSGPSVRKASLS
..:.:. .:. :... :.... .: : . . ... . .. .. . :
XP_011 VSKQANANRQ--KGQLAVERAKQVEEFLQRKREAMQNKARAEGHMGILQNLAAMYGGRPS
520 530 540 550 560 570
600 610 620 630 640 650
pF1KE3 VAGPGKPQEEDQPLPARRLSS-DCSVTQERKQIHCLSEDELSSSTSSTDKSDGDYGEGKG
. :::..... . :: . . .::.::. . : :......::.
XP_011 SSRGGKPRNKEEEVYLARLRQIRLQNFNERQQIKAKLRGE---------KKEANHSEGQE
580 590 600 610 620
660 670 680 690 700 710
pF1KE3 QTNEINALVQLMTQTLKLDSKESCEDVPVANPVSEFKLHRKYRDTLILHGKVAEE---AE
..: . . :..: .. .. .: : . .:.:: ... . :: :: :.
XP_011 GSEEADM------RRKKIESLKAHANARAA--VLKEQLERKRKEAYEREKKVWEEHLVAK
630 640 650 660 670
720 730 740 750 760
pF1KE3 EIHFKELPSAI-------MPGSEKIRRLVEVLRTDVIRGLGVQLLEQVYDLLEEEDEFDR
.. ... . :.....: .. : :.... .::
XP_011 GVKSSDVSPPLGQHETGGSPSKQQMRSVISV--TSALKEVGVDC
680 690 700 710
770 780 790
pF1KE3 EVRLREHMGEKYTTYSVKARQLKFFEENMNF
795 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 16:11:33 2016 done: Mon Nov 7 16:11:35 2016
Total Scan time: 11.810 Total Display time: 0.230
Function used was FASTA [36.3.4 Apr, 2011]