Result of FASTA (omim) for
pFN21AE3306
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3306, 770 aa
1>>>pF1KE3306 770 - 770 aa - 770 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 17.0614+/-0.000661; mu= -32.6653+/- 0.041
mean_var=1054.9614+/-223.506, 0's: 0 Z-trim(122.3): 700 B-trim: 2149 in 1/58
Lambda= 0.039487
statistics sampled from 39436 (40321) to 39436 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.749), E-opt: 0.2 (0.473), width: 16
Scan time: 11.750
The best scores are: opt bits E(85289)
NP_277071 (OMIM: 116951) cyclin-dependent kinase 1 ( 770) 5048 304.1 1.5e-81
NP_001278274 (OMIM: 176873) cyclin-dependent kinas ( 772) 5038 303.5 2.2e-81
NP_076916 (OMIM: 116951) cyclin-dependent kinase 1 ( 780) 4376 265.8 5e-70
NP_277021 (OMIM: 176873) cyclin-dependent kinase 1 ( 782) 4374 265.7 5.4e-70
NP_277024 (OMIM: 176873) cyclin-dependent kinase 1 ( 748) 4365 265.1 7.5e-70
XP_016858415 (OMIM: 176873) PREDICTED: cyclin-depe ( 781) 4162 253.6 2.3e-66
XP_016858414 (OMIM: 176873) PREDICTED: cyclin-depe ( 791) 4152 253.0 3.5e-66
NP_001300911 (OMIM: 116951) cyclin-dependent kinas ( 779) 4137 252.2 6.3e-66
NP_277025 (OMIM: 176873) cyclin-dependent kinase 1 ( 565) 3706 227.5 1.2e-58
NP_001778 (OMIM: 176873) cyclin-dependent kinase 1 ( 795) 3657 224.8 1.1e-57
XP_016858417 (OMIM: 176873) PREDICTED: cyclin-depe ( 761) 3654 224.6 1.2e-57
XP_006711128 (OMIM: 176873) PREDICTED: cyclin-depe ( 785) 3650 224.4 1.4e-57
XP_016858416 (OMIM: 176873) PREDICTED: cyclin-depe ( 770) 3647 224.3 1.6e-57
XP_011540796 (OMIM: 176873) PREDICTED: cyclin-depe ( 770) 3647 224.3 1.6e-57
XP_011540793 (OMIM: 176873) PREDICTED: cyclin-depe ( 804) 3647 224.3 1.6e-57
XP_011540794 (OMIM: 176873) PREDICTED: cyclin-depe ( 804) 3647 224.3 1.6e-57
XP_011540792 (OMIM: 176873) PREDICTED: cyclin-depe ( 804) 3647 224.3 1.6e-57
XP_011540795 (OMIM: 176873) PREDICTED: cyclin-depe ( 794) 3646 224.2 1.7e-57
XP_011540797 (OMIM: 176873) PREDICTED: cyclin-depe ( 760) 3643 224.0 1.8e-57
NP_001300825 (OMIM: 116951) cyclin-dependent kinas ( 783) 3633 223.5 2.8e-57
XP_011540798 (OMIM: 176873) PREDICTED: cyclin-depe ( 578) 3454 213.1 2.6e-54
NP_277022 (OMIM: 176873) cyclin-dependent kinase 1 ( 526) 3426 211.5 7.5e-54
NP_443714 (OMIM: 603464) cyclin-dependent kinase 1 ( 360) 1224 85.9 3.4e-16
XP_006721371 (OMIM: 603464) PREDICTED: cyclin-depe ( 354) 1177 83.2 2.1e-15
XP_006721373 (OMIM: 603464) PREDICTED: cyclin-depe ( 343) 1167 82.6 3.1e-15
XP_016879296 (OMIM: 603464) PREDICTED: cyclin-depe ( 337) 1128 80.4 1.4e-14
NP_001153839 (OMIM: 603464) cyclin-dependent kinas ( 289) 1031 74.8 5.9e-13
XP_016879297 (OMIM: 603464) PREDICTED: cyclin-depe ( 289) 1031 74.8 5.9e-13
NP_001092003 (OMIM: 603464) cyclin-dependent kinas ( 283) 984 72.1 3.7e-12
XP_016879298 (OMIM: 603464) PREDICTED: cyclin-depe ( 283) 984 72.1 3.7e-12
NP_443713 (OMIM: 603464) cyclin-dependent kinase 1 ( 272) 974 71.5 5.4e-12
XP_016879299 (OMIM: 603464) PREDICTED: cyclin-depe ( 272) 974 71.5 5.4e-12
NP_001249 (OMIM: 123828) cyclin-dependent kinase 3 ( 305) 912 68.0 6.7e-11
NP_001789 (OMIM: 116953) cyclin-dependent kinase 2 ( 298) 905 67.6 8.7e-11
NP_001777 (OMIM: 116940) cyclin-dependent kinase 1 ( 297) 834 63.6 1.4e-09
NP_001307847 (OMIM: 116940) cyclin-dependent kinas ( 297) 834 63.6 1.4e-09
XP_005270360 (OMIM: 116940) PREDICTED: cyclin-depe ( 297) 834 63.6 1.4e-09
NP_001790 (OMIM: 601955) cyclin-dependent kinase 7 ( 346) 827 63.2 2.1e-09
XP_011521719 (OMIM: 603464) PREDICTED: cyclin-depe ( 261) 812 62.2 3.1e-09
NP_001034892 (OMIM: 610076) cyclin-dependent kinas ( 346) 814 62.5 3.5e-09
NP_004926 (OMIM: 123831,616342) cyclin-dependent-l ( 292) 809 62.1 3.8e-09
XP_011521710 (OMIM: 603464) PREDICTED: cyclin-depe ( 369) 812 62.4 4e-09
XP_011521709 (OMIM: 603464) PREDICTED: cyclin-depe ( 375) 812 62.4 4e-09
XP_011521708 (OMIM: 603464) PREDICTED: cyclin-depe ( 386) 812 62.4 4.1e-09
XP_011521707 (OMIM: 603464) PREDICTED: cyclin-depe ( 392) 812 62.4 4.1e-09
NP_002586 (OMIM: 603440) cyclin-dependent kinase 1 ( 523) 808 62.3 5.9e-09
XP_016874894 (OMIM: 603440) PREDICTED: cyclin-depe ( 523) 808 62.3 5.9e-09
XP_016874895 (OMIM: 603440) PREDICTED: cyclin-depe ( 523) 808 62.3 5.9e-09
NP_001163935 (OMIM: 603440) cyclin-dependent kinas ( 523) 804 62.1 6.9e-09
XP_016870050 (OMIM: 610076) PREDICTED: cyclin-depe ( 351) 794 61.4 7.8e-09
>>NP_277071 (OMIM: 116951) cyclin-dependent kinase 11A i (770 aa)
initn: 5048 init1: 5048 opt: 5048 Z-score: 1585.2 bits: 304.1 E(85289): 1.5e-81
Smith-Waterman score: 5048; 99.2% identity (99.6% similar) in 770 aa overlap (1-770:1-770)
10 20 30 40 50 60
pF1KE3 MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEI
:::::::::::::::::::::::::::::::::::::::::::::::::::::::: :::
NP_277 MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKWKHARVKEREHE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_277 TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKWKHARVKEREHE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 RRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_277 RRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 ERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_277 ERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 KEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_277 KEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 EEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSRESE
:::::::::::::::::::::::::::::::::::::::::::::::::::::::: :::
NP_277 EEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 EAEEEVGEGTPQSSALTEGDYVPDSPALLPIELKQELPKYLPALQGCRSVEEFQCLNRIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_277 EAEEEVGEGTPQSSALTEGDYVPDSPALLPIELKQELPKYLPALQGCRSVEEFQCLNRIE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 EGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREIVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_277 EGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREIVV
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 GSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_277 GSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDLKT
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 SNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKEYSTAVDMWSVG
::::::::::::::::::::::::::::::::::: ::::::::::::::::::::::::
NP_277 SNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVG
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 CIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKKMTFSEHPYNNLR
:::::::::::::::.:::::::::::.::::::::::::::::.:::::::::::::::
NP_277 CIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKMTFSEHPYNNLR
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 KRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSMFPTWPAKSEQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_277 KRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSMFPTWPAKSEQQ
670 680 690 700 710 720
730 740 750 760 770
pF1KE3 RVKRGTSPRPPEGGLGYSQLGDDDLKETGFHLTTTNQGASAAGPGFSLKF
::::::::::::::::::::::::::::::::::::::::::::::::::
NP_277 RVKRGTSPRPPEGGLGYSQLGDDDLKETGFHLTTTNQGASAAGPGFSLKF
730 740 750 760 770
>>NP_001278274 (OMIM: 176873) cyclin-dependent kinase 11 (772 aa)
initn: 4327 init1: 4327 opt: 5038 Z-score: 1582.1 bits: 303.5 E(85289): 2.2e-81
Smith-Waterman score: 5038; 99.2% identity (99.4% similar) in 772 aa overlap (1-770:1-772)
10 20 30 40 50 60
pF1KE3 MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEI
10 20 30 40 50 60
70 80 90 100 110
pF1KE3 TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKWKHARVKE--RE
::::::::::::::::::::::::::::::::::::.::::::::::: ::::::: ::
NP_001 TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKERE
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE3 HERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQRE
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE3 QKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRK
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE3 PVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEES
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE3 EEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSRE
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::: :
NP_001 EEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGE
310 320 330 340 350 360
360 370 380 390 400 410
pF1KE3 SEEAEEEVGEGTPQSSALTEGDYVPDSPALLPIELKQELPKYLPALQGCRSVEEFQCLNR
:::::::::::::::::::::::::::::: :::::::::::::::::::::::::::::
NP_001 SEEAEEEVGEGTPQSSALTEGDYVPDSPALSPIELKQELPKYLPALQGCRSVEEFQCLNR
370 380 390 400 410 420
420 430 440 450 460 470
pF1KE3 IEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTVREI
430 440 450 460 470 480
480 490 500 510 520 530
pF1KE3 VVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILHRDL
490 500 510 520 530 540
540 550 560 570 580 590
pF1KE3 KTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKEYSTAVDMWS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKEYSTAVDMWS
550 560 570 580 590 600
600 610 620 630 640 650
pF1KE3 VGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKKMTFSEHPYNN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKKMTFSEHPYNN
610 620 630 640 650 660
660 670 680 690 700 710
pF1KE3 LRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSMFPTWPAKSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSMFPTWPAKSE
670 680 690 700 710 720
720 730 740 750 760 770
pF1KE3 QQRVKRGTSPRPPEGGLGYSQLGDDDLKETGFHLTTTNQGASAAGPGFSLKF
::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QQRVKRGTSPRPPEGGLGYSQLGDDDLKETGFHLTTTNQGASAAGPGFSLKF
730 740 750 760 770
>>NP_076916 (OMIM: 116951) cyclin-dependent kinase 11A i (780 aa)
initn: 4330 init1: 4330 opt: 4376 Z-score: 1378.2 bits: 265.8 E(85289): 5e-70
Smith-Waterman score: 5000; 97.8% identity (98.2% similar) in 780 aa overlap (1-770:1-780)
10 20 30 40 50 60
pF1KE3 MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEI
:::::::::::::::::::::::::::::::::::::::::::::::::::::::: :::
NP_076 MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEI
10 20 30 40 50 60
70 80 90 100 110
pF1KE3 TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEK----------WK
:::::::::::::::::::::::::::::::::::::::::::::::: :
NP_076 TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKCRHHSHSAEGGK
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE3 HARVKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_076 HARVKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMR
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE3 EQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_076 EQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRER
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE3 FELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_076 FELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEE
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE3 EGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_076 EGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPES
310 320 330 340 350 360
360 370 380 390 400 410
pF1KE3 RFDRDSRESEEAEEEVGEGTPQSSALTEGDYVPDSPALLPIELKQELPKYLPALQGCRSV
:::::: :::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_076 RFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPALLPIELKQELPKYLPALQGCRSV
370 380 390 400 410 420
420 430 440 450 460 470
pF1KE3 EEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_076 EEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHP
430 440 450 460 470 480
480 490 500 510 520 530
pF1KE3 NIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_076 NIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHD
490 500 510 520 530 540
540 550 560 570 580 590
pF1KE3 NWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKEY
::::::::::::::::::::::::::::::::::::::::::::: ::::::::::::::
NP_076 NWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKEY
550 560 570 580 590 600
600 610 620 630 640 650
pF1KE3 STAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKKMT
:::::::::::::::::::::::::.:::::::::::.::::::::::::::::.:::::
NP_076 STAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKMT
610 620 630 640 650 660
660 670 680 690 700 710
pF1KE3 FSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSMF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_076 FSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSMF
670 680 690 700 710 720
720 730 740 750 760 770
pF1KE3 PTWPAKSEQQRVKRGTSPRPPEGGLGYSQLGDDDLKETGFHLTTTNQGASAAGPGFSLKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_076 PTWPAKSEQQRVKRGTSPRPPEGGLGYSQLGDDDLKETGFHLTTTNQGASAAGPGFSLKF
730 740 750 760 770 780
>>NP_277021 (OMIM: 176873) cyclin-dependent kinase 11B i (782 aa)
initn: 4346 init1: 4346 opt: 4374 Z-score: 1377.6 bits: 265.7 E(85289): 5.4e-70
Smith-Waterman score: 5008; 98.0% identity (98.1% similar) in 782 aa overlap (1-770:1-782)
10 20 30 40 50 60
pF1KE3 MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_277 MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEI
10 20 30 40 50 60
70 80 90 100 110
pF1KE3 TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKW----------K
::::::::::::::::::::::::::::::::::::.::::::::::: :
NP_277 TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRRHRSHSAEGGK
70 80 90 100 110 120
120 130 140 150 160
pF1KE3 HARVKE--REHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERK
:::::: ::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_277 HARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERK
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE3 MREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_277 MREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPR
190 200 210 220 230 240
230 240 250 260 270 280
pF1KE3 ERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_277 ERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEE
250 260 270 280 290 300
290 300 310 320 330 340
pF1KE3 EEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_277 EEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVP
310 320 330 340 350 360
350 360 370 380 390 400
pF1KE3 ESRFDRDSRESEEAEEEVGEGTPQSSALTEGDYVPDSPALLPIELKQELPKYLPALQGCR
:::::::: ::::::::::::::::::::::::::::::: :::::::::::::::::::
NP_277 ESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPALSPIELKQELPKYLPALQGCR
370 380 390 400 410 420
410 420 430 440 450 460
pF1KE3 SVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_277 SVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQ
430 440 450 460 470 480
470 480 490 500 510 520
pF1KE3 HPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_277 HPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHL
490 500 510 520 530 540
530 540 550 560 570 580
pF1KE3 HDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_277 HDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAK
550 560 570 580 590 600
590 600 610 620 630 640
pF1KE3 EYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_277 EYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKK
610 620 630 640 650 660
650 660 670 680 690 700
pF1KE3 MTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_277 MTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPS
670 680 690 700 710 720
710 720 730 740 750 760
pF1KE3 MFPTWPAKSEQQRVKRGTSPRPPEGGLGYSQLGDDDLKETGFHLTTTNQGASAAGPGFSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_277 MFPTWPAKSEQQRVKRGTSPRPPEGGLGYSQLGDDDLKETGFHLTTTNQGASAAGPGFSL
730 740 750 760 770 780
770
pF1KE3 KF
::
NP_277 KF
>>NP_277024 (OMIM: 176873) cyclin-dependent kinase 11B i (748 aa)
initn: 4346 init1: 4346 opt: 4365 Z-score: 1375.0 bits: 265.1 E(85289): 7.5e-70
Smith-Waterman score: 4774; 97.5% identity (98.0% similar) in 748 aa overlap (35-770:1-748)
10 20 30 40 50 60
pF1KE3 KDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRN
...:::::::::::::::::::::::::::
NP_277 MSQSDDRDSKRDSLEEGELRDHRMEITIRN
10 20 30
70 80 90 100 110
pF1KE3 SPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKW----------KHARV
::::::::::::::::::::::::::::::::.::::::::::: :::::
NP_277 SPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRRHRSHSAEGGKHARV
40 50 60 70 80 90
120 130 140 150 160 170
pF1KE3 KE--REHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQ
:: ::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_277 KEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQ
100 110 120 130 140 150
180 190 200 210 220 230
pF1KE3 QKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_277 QKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFE
160 170 180 190 200 210
240 250 260 270 280 290
pF1KE3 LGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_277 LGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEG
220 230 240 250 260 270
300 310 320 330 340 350
pF1KE3 STSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_277 STSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRF
280 290 300 310 320 330
360 370 380 390 400 410
pF1KE3 DRDSRESEEAEEEVGEGTPQSSALTEGDYVPDSPALLPIELKQELPKYLPALQGCRSVEE
:::: ::::::::::::::::::::::::::::::: :::::::::::::::::::::::
NP_277 DRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPALSPIELKQELPKYLPALQGCRSVEE
340 350 360 370 380 390
420 430 440 450 460 470
pF1KE3 FQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_277 FQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNI
400 410 420 430 440 450
480 490 500 510 520 530
pF1KE3 VTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_277 VTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNW
460 470 480 490 500 510
540 550 560 570 580 590
pF1KE3 ILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKEYST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_277 ILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKEYST
520 530 540 550 560 570
600 610 620 630 640 650
pF1KE3 AVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKKMTFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_277 AVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKKMTFS
580 590 600 610 620 630
660 670 680 690 700 710
pF1KE3 EHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSMFPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_277 EHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSMFPT
640 650 660 670 680 690
720 730 740 750 760 770
pF1KE3 WPAKSEQQRVKRGTSPRPPEGGLGYSQLGDDDLKETGFHLTTTNQGASAAGPGFSLKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_277 WPAKSEQQRVKRGTSPRPPEGGLGYSQLGDDDLKETGFHLTTTNQGASAAGPGFSLKF
700 710 720 730 740
>>XP_016858415 (OMIM: 176873) PREDICTED: cyclin-dependen (781 aa)
initn: 4110 init1: 4110 opt: 4162 Z-score: 1312.3 bits: 253.6 E(85289): 2.3e-66
Smith-Waterman score: 5010; 98.1% identity (98.2% similar) in 781 aa overlap (1-770:1-781)
10 20 30 40 50 60
pF1KE3 MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEI
10 20 30 40 50 60
70 80 90 100 110
pF1KE3 TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKWKHARVKE--RE
::::::::::::::::::::::::::::::::::::.::::::::::: ::::::: ::
XP_016 TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRKHARVKEKERE
70 80 90 100 110 120
120 130 140 150 160
pF1KE3 HERRKRHREEQDKARREWERQKRREMAREHSRRER---------DRLEQLERKRERERKM
::::::::::::::::::::::::::::::::::: ::::::::::::::::
XP_016 HERRKRHREEQDKARREWERQKRREMAREHSRRERGNDGVCLFRDRLEQLERKRERERKM
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE3 REQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 REQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRE
190 200 210 220 230 240
230 240 250 260 270 280
pF1KE3 RFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEE
250 260 270 280 290 300
290 300 310 320 330 340
pF1KE3 EEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPE
310 320 330 340 350 360
350 360 370 380 390 400
pF1KE3 SRFDRDSRESEEAEEEVGEGTPQSSALTEGDYVPDSPALLPIELKQELPKYLPALQGCRS
::::::: ::::::::::::::::::::::::::::::: ::::::::::::::::::::
XP_016 SRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPALSPIELKQELPKYLPALQGCRS
370 380 390 400 410 420
410 420 430 440 450 460
pF1KE3 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH
430 440 450 460 470 480
470 480 490 500 510 520
pF1KE3 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLH
490 500 510 520 530 540
530 540 550 560 570 580
pF1KE3 DNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKE
550 560 570 580 590 600
590 600 610 620 630 640
pF1KE3 YSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKKM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKKM
610 620 630 640 650 660
650 660 670 680 690 700
pF1KE3 TFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSM
670 680 690 700 710 720
710 720 730 740 750 760
pF1KE3 FPTWPAKSEQQRVKRGTSPRPPEGGLGYSQLGDDDLKETGFHLTTTNQGASAAGPGFSLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FPTWPAKSEQQRVKRGTSPRPPEGGLGYSQLGDDDLKETGFHLTTTNQGASAAGPGFSLK
730 740 750 760 770 780
770
pF1KE3 F
:
XP_016 F
>>XP_016858414 (OMIM: 176873) PREDICTED: cyclin-dependen (791 aa)
initn: 4110 init1: 4110 opt: 4152 Z-score: 1309.2 bits: 253.0 E(85289): 3.5e-66
Smith-Waterman score: 4980; 96.8% identity (97.0% similar) in 791 aa overlap (1-770:1-791)
10 20 30 40 50 60
pF1KE3 MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEI
10 20 30 40 50 60
70 80 90 100 110
pF1KE3 TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKW----------K
::::::::::::::::::::::::::::::::::::.::::::::::: :
XP_016 TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRRHRSHSAEGGK
70 80 90 100 110 120
120 130 140 150
pF1KE3 HARVKE--REHERRKRHREEQDKARREWERQKRREMAREHSRRER---------DRLEQL
:::::: ::::::::::::::::::::::::::::::::::::: ::::::
XP_016 HARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERGNDGVCLFRDRLEQL
130 140 150 160 170 180
160 170 180 190 200 210
pF1KE3 ERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHW
190 200 210 220 230 240
220 230 240 250 260 270
pF1KE3 SRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSE
250 260 270 280 290 300
280 290 300 310 320 330
pF1KE3 EEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERE
310 320 330 340 350 360
340 350 360 370 380 390
pF1KE3 NENHLLVVPESRFDRDSRESEEAEEEVGEGTPQSSALTEGDYVPDSPALLPIELKQELPK
::::::::::::::::: ::::::::::::::::::::::::::::::: ::::::::::
XP_016 NENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPALSPIELKQELPK
370 380 390 400 410 420
400 410 420 430 440 450
pF1KE3 YLPALQGCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YLPALQGCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLR
430 440 450 460 470 480
460 470 480 490 500 510
pF1KE3 EINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMI
490 500 510 520 530 540
520 530 540 550 560 570
pF1KE3 QLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYR
550 560 570 580 590 600
580 590 600 610 620 630
pF1KE3 APELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 APELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPG
610 620 630 640 650 660
640 650 660 670 680 690
pF1KE3 YSELPAVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YSELPAVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFR
670 680 690 700 710 720
700 710 720 730 740 750
pF1KE3 ETPLPIDPSMFPTWPAKSEQQRVKRGTSPRPPEGGLGYSQLGDDDLKETGFHLTTTNQGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ETPLPIDPSMFPTWPAKSEQQRVKRGTSPRPPEGGLGYSQLGDDDLKETGFHLTTTNQGA
730 740 750 760 770 780
760 770
pF1KE3 SAAGPGFSLKF
:::::::::::
XP_016 SAAGPGFSLKF
790
>>NP_001300911 (OMIM: 116951) cyclin-dependent kinase 11 (779 aa)
initn: 4092 init1: 4092 opt: 4137 Z-score: 1304.6 bits: 252.2 E(85289): 6.3e-66
Smith-Waterman score: 5020; 98.1% identity (98.5% similar) in 779 aa overlap (1-770:1-779)
10 20 30 40 50 60
pF1KE3 MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEI
:::::::::::::::::::::::::::::::::::::::::::::::::::::::: :::
NP_001 MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKWKHARVKEREHE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKWKHARVKEREHE
70 80 90 100 110 120
130 140 150 160 170
pF1KE3 RRKRHREEQDKARREWERQKRREMAREHSRRER---------DRLEQLERKRERERKMRE
::::::::::::::::::::::::::::::::: ::::::::::::::::::
NP_001 RRKRHREEQDKARREWERQKRREMAREHSRRERGNDGVCLFRDRLEQLERKRERERKMRE
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE3 QQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERF
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE3 ELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEE
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE3 GSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESR
310 320 330 340 350 360
360 370 380 390 400 410
pF1KE3 FDRDSRESEEAEEEVGEGTPQSSALTEGDYVPDSPALLPIELKQELPKYLPALQGCRSVE
::::: ::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPALLPIELKQELPKYLPALQGCRSVE
370 380 390 400 410 420
420 430 440 450 460 470
pF1KE3 EFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPN
430 440 450 460 470 480
480 490 500 510 520 530
pF1KE3 IVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDN
490 500 510 520 530 540
540 550 560 570 580 590
pF1KE3 WILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKEYS
:::::::::::::::::::::::::::::::::::::::::::: :::::::::::::::
NP_001 WILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKEYS
550 560 570 580 590 600
600 610 620 630 640 650
pF1KE3 TAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKKMTF
::::::::::::::::::::::::.:::::::::::.::::::::::::::::.::::::
NP_001 TAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKKMTF
610 620 630 640 650 660
660 670 680 690 700 710
pF1KE3 SEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSMFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSMFP
670 680 690 700 710 720
720 730 740 750 760 770
pF1KE3 TWPAKSEQQRVKRGTSPRPPEGGLGYSQLGDDDLKETGFHLTTTNQGASAAGPGFSLKF
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TWPAKSEQQRVKRGTSPRPPEGGLGYSQLGDDDLKETGFHLTTTNQGASAAGPGFSLKF
730 740 750 760 770
>>NP_277025 (OMIM: 176873) cyclin-dependent kinase 11B i (565 aa)
initn: 3706 init1: 3706 opt: 3706 Z-score: 1173.6 bits: 227.5 E(85289): 1.2e-58
Smith-Waterman score: 3706; 99.6% identity (99.6% similar) in 565 aa overlap (206-770:1-565)
180 190 200 210 220 230
pF1KE3 QREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGD
::::::::::::::::::::::::::::::
NP_277 MREDYSDKVKASHWSRSPPRPPRERFELGD
10 20 30
240 250 260 270 280 290
pF1KE3 GRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_277 GRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTS
40 50 60 70 80 90
300 310 320 330 340 350
pF1KE3 EESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_277 EESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRD
100 110 120 130 140 150
360 370 380 390 400 410
pF1KE3 SRESEEAEEEVGEGTPQSSALTEGDYVPDSPALLPIELKQELPKYLPALQGCRSVEEFQC
: ::::::::::::::::::::::::::::::: ::::::::::::::::::::::::::
NP_277 SGESEEAEEEVGEGTPQSSALTEGDYVPDSPALSPIELKQELPKYLPALQGCRSVEEFQC
160 170 180 190 200 210
420 430 440 450 460 470
pF1KE3 LNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_277 LNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQHPNIVTV
220 230 240 250 260 270
480 490 500 510 520 530
pF1KE3 REIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_277 REIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDNWILH
280 290 300 310 320 330
540 550 560 570 580 590
pF1KE3 RDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKEYSTAVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_277 RDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKEYSTAVD
340 350 360 370 380 390
600 610 620 630 640 650
pF1KE3 MWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKKMTFSEHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_277 MWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKKMTFSEHP
400 410 420 430 440 450
660 670 680 690 700 710
pF1KE3 YNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSMFPTWPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_277 YNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSMFPTWPA
460 470 480 490 500 510
720 730 740 750 760 770
pF1KE3 KSEQQRVKRGTSPRPPEGGLGYSQLGDDDLKETGFHLTTTNQGASAAGPGFSLKF
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_277 KSEQQRVKRGTSPRPPEGGLGYSQLGDDDLKETGFHLTTTNQGASAAGPGFSLKF
520 530 540 550 560
>>NP_001778 (OMIM: 176873) cyclin-dependent kinase 11B i (795 aa)
initn: 3451 init1: 3451 opt: 3657 Z-score: 1156.7 bits: 224.8 E(85289): 1.1e-57
Smith-Waterman score: 4968; 96.2% identity (96.5% similar) in 795 aa overlap (1-770:1-795)
10 20 30 40 50 60
pF1KE3 MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEI
10 20 30 40 50 60
70 80 90 100 110
pF1KE3 TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKW----------K
::::::::::::::::::::::::::::::::::::.::::::::::: :
NP_001 TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKAHHRKDEKRKEKRRHRSHSAEGGK
70 80 90 100 110 120
120 130 140 150 160
pF1KE3 HARVKE--REHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERK
:::::: ::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERK
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE3 MREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPR
190 200 210 220 230 240
230 240 250 260 270
pF1KE3 ERFELGDGRKP-------------VKEEKMEERDLLSDLQDISDSERKTSSAESSSAESG
::::::::::: .:::::::::::::::::::::::::::::::::::
NP_001 ERFELGDGRKPGEARPAPAQKPAQLKEEKMEERDLLSDLQDISDSERKTSSAESSSAESG
250 260 270 280 290 300
280 290 300 310 320 330
pF1KE3 SGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSED
310 320 330 340 350 360
340 350 360 370 380 390
pF1KE3 EERENENHLLVVPESRFDRDSRESEEAEEEVGEGTPQSSALTEGDYVPDSPALLPIELKQ
::::::::::::::::::::: ::::::::::::::::::::::::::::::: ::::::
NP_001 EERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPALSPIELKQ
370 380 390 400 410 420
400 410 420 430 440 450
pF1KE3 ELPKYLPALQGCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELPKYLPALQGCRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPI
430 440 450 460 470 480
460 470 480 490 500 510
pF1KE3 TSLREINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TSLREINTILKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVK
490 500 510 520 530 540
520 530 540 550 560 570
pF1KE3 TLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLMIQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVT
550 560 570 580 590 600
580 590 600 610 620 630
pF1KE3 LWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEK
610 620 630 640 650 660
640 650 660 670 680 690
pF1KE3 IWPGYSELPAVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IWPGYSELPAVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKH
670 680 690 700 710 720
700 710 720 730 740 750
pF1KE3 EYFRETPLPIDPSMFPTWPAKSEQQRVKRGTSPRPPEGGLGYSQLGDDDLKETGFHLTTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EYFRETPLPIDPSMFPTWPAKSEQQRVKRGTSPRPPEGGLGYSQLGDDDLKETGFHLTTT
730 740 750 760 770 780
760 770
pF1KE3 NQGASAAGPGFSLKF
:::::::::::::::
NP_001 NQGASAAGPGFSLKF
790
770 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 17:20:46 2016 done: Mon Nov 7 17:20:48 2016
Total Scan time: 11.750 Total Display time: 0.190
Function used was FASTA [36.3.4 Apr, 2011]