Result of FASTA (omim) for
pFN21AE3293
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3293, 765 aa
1>>>pF1KE3293 765 - 765 aa - 765 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 19.1386+/-0.000912; mu= -50.0671+/- 0.055
mean_var=1288.5964+/-283.752, 0's: 0 Z-trim(112.7): 800 B-trim: 1257 in 1/54
Lambda= 0.035729
statistics sampled from 21094 (21721) to 21094 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.591), E-opt: 0.2 (0.255), width: 16
Scan time: 8.160
The best scores are: opt bits E(85289)
NP_848605 (OMIM: 608774) ankyrin repeat and protei ( 765) 5123 282.1 6.2e-75
XP_011541039 (OMIM: 608774) PREDICTED: ankyrin rep ( 766) 5111 281.4 9.5e-75
XP_016872964 (OMIM: 608774) PREDICTED: ankyrin rep ( 775) 3602 203.7 2.5e-51
XP_011541040 (OMIM: 608774) PREDICTED: ankyrin rep ( 702) 3590 203.0 3.6e-51
XP_011541038 (OMIM: 608774) PREDICTED: ankyrin rep ( 776) 3590 203.0 3.8e-51
NP_065690 (OMIM: 263650,605706) receptor-interacti ( 784) 920 65.4 1e-09
XP_016863601 (OMIM: 106410,600919) PREDICTED: anky (1689) 812 60.2 8.3e-08
XP_016863597 (OMIM: 106410,600919) PREDICTED: anky (1772) 812 60.2 8.5e-08
XP_016871638 (OMIM: 600465,615493) PREDICTED: anky (1720) 811 60.2 8.7e-08
XP_016871637 (OMIM: 600465,615493) PREDICTED: anky (1725) 811 60.2 8.7e-08
XP_016871636 (OMIM: 600465,615493) PREDICTED: anky (1735) 811 60.2 8.7e-08
XP_016871635 (OMIM: 600465,615493) PREDICTED: anky (1737) 811 60.2 8.7e-08
XP_016871634 (OMIM: 600465,615493) PREDICTED: anky (1738) 811 60.2 8.7e-08
XP_016871633 (OMIM: 600465,615493) PREDICTED: anky (1741) 811 60.2 8.7e-08
XP_016871632 (OMIM: 600465,615493) PREDICTED: anky (1742) 811 60.2 8.7e-08
XP_016871631 (OMIM: 600465,615493) PREDICTED: anky (1747) 811 60.2 8.8e-08
XP_016871630 (OMIM: 600465,615493) PREDICTED: anky (1751) 811 60.2 8.8e-08
XP_016871629 (OMIM: 600465,615493) PREDICTED: anky (1763) 811 60.2 8.8e-08
XP_016871628 (OMIM: 600465,615493) PREDICTED: anky (1764) 811 60.2 8.8e-08
XP_016871627 (OMIM: 600465,615493) PREDICTED: anky (1785) 811 60.2 8.9e-08
XP_016871626 (OMIM: 600465,615493) PREDICTED: anky (1786) 811 60.2 8.9e-08
XP_016871625 (OMIM: 600465,615493) PREDICTED: anky (1795) 811 60.2 8.9e-08
XP_016871624 (OMIM: 600465,615493) PREDICTED: anky (1838) 811 60.2 9.1e-08
XP_016871623 (OMIM: 600465,615493) PREDICTED: anky (1845) 811 60.2 9.1e-08
XP_016871622 (OMIM: 600465,615493) PREDICTED: anky (1850) 811 60.2 9.1e-08
XP_016871621 (OMIM: 600465,615493) PREDICTED: anky (1855) 811 60.2 9.1e-08
NP_001191332 (OMIM: 600465,615493) ankyrin-3 isofo (1861) 811 60.2 9.1e-08
XP_016871620 (OMIM: 600465,615493) PREDICTED: anky (1862) 811 60.2 9.1e-08
XP_016871619 (OMIM: 600465,615493) PREDICTED: anky (1866) 811 60.2 9.2e-08
NP_001307803 (OMIM: 600465,615493) ankyrin-3 isofo (1867) 811 60.2 9.2e-08
NP_001191333 (OMIM: 600465,615493) ankyrin-3 isofo (1868) 811 60.2 9.2e-08
XP_005269772 (OMIM: 600465,615493) PREDICTED: anky (1885) 811 60.2 9.2e-08
XP_016871618 (OMIM: 600465,615493) PREDICTED: anky (1888) 811 60.2 9.2e-08
XP_016871617 (OMIM: 600465,615493) PREDICTED: anky (1889) 811 60.2 9.2e-08
XP_006717865 (OMIM: 600465,615493) PREDICTED: anky (1898) 811 60.2 9.3e-08
XP_016871616 (OMIM: 600465,615493) PREDICTED: anky (2603) 811 60.4 1.2e-07
XP_016871615 (OMIM: 600465,615493) PREDICTED: anky (2612) 811 60.4 1.2e-07
XP_016871614 (OMIM: 600465,615493) PREDICTED: anky (2646) 811 60.4 1.2e-07
XP_016871613 (OMIM: 600465,615493) PREDICTED: anky (2647) 811 60.4 1.2e-07
XP_016871612 (OMIM: 600465,615493) PREDICTED: anky (2655) 811 60.4 1.2e-07
XP_011538011 (OMIM: 600465,615493) PREDICTED: anky (2656) 811 60.4 1.2e-07
XP_016871611 (OMIM: 600465,615493) PREDICTED: anky (2728) 811 60.4 1.2e-07
XP_006717859 (OMIM: 600465,615493) PREDICTED: anky (2758) 811 60.4 1.2e-07
XP_011538010 (OMIM: 600465,615493) PREDICTED: anky (2759) 811 60.4 1.2e-07
XP_016863596 (OMIM: 106410,600919) PREDICTED: anky (1797) 797 59.5 1.5e-07
XP_016863595 (OMIM: 106410,600919) PREDICTED: anky (1806) 797 59.5 1.5e-07
NP_065210 (OMIM: 182900,612641) ankyrin-1 isoform (1719) 796 59.4 1.5e-07
XP_016863591 (OMIM: 106410,600919) PREDICTED: anky (1838) 797 59.5 1.5e-07
XP_011542807 (OMIM: 182900,612641) PREDICTED: anky (1751) 796 59.4 1.5e-07
XP_011542806 (OMIM: 182900,612641) PREDICTED: anky (1752) 796 59.4 1.5e-07
>>NP_848605 (OMIM: 608774) ankyrin repeat and protein ki (765 aa)
initn: 5123 init1: 5123 opt: 5123 Z-score: 1466.3 bits: 282.1 E(85289): 6.2e-75
Smith-Waterman score: 5123; 100.0% identity (100.0% similar) in 765 aa overlap (1-765:1-765)
10 20 30 40 50 60
pF1KE3 MAADPTELRLGSLPVFTRDDFEGDWRLVASGGFSQVFQARHRRWRTEYAIKCAPCLPPDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_848 MAADPTELRLGSLPVFTRDDFEGDWRLVASGGFSQVFQARHRRWRTEYAIKCAPCLPPDA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 ASSDVNYLIEEAAKMKKIKFQHIVSIYGVCKQPLGIVMEFMANGSLEKVLSTHSLCWKLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_848 ASSDVNYLIEEAAKMKKIKFQHIVSIYGVCKQPLGIVMEFMANGSLEKVLSTHSLCWKLR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 FRIIHETSLAMNFLHSIKPPLLHLDLKPGNILLDSNMHVKISDFGLSKWMEQSTRMQYIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_848 FRIIHETSLAMNFLHSIKPPLLHLDLKPGNILLDSNMHVKISDFGLSKWMEQSTRMQYIE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 RSALRGMLSYIPPEMFLESNKAPGPKYDVYSFAIVIWELLTQKKPYSGFNMMMIIIRVAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_848 RSALRGMLSYIPPEMFLESNKAPGPKYDVYSFAIVIWELLTQKKPYSGFNMMMIIIRVAA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 GMRPSLQPVSDQWPSEAQQMVDLMKRCWDQDPKKRPCFLDITIETDILLSLLQSRVAVPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_848 GMRPSLQPVSDQWPSEAQQMVDLMKRCWDQDPKKRPCFLDITIETDILLSLLQSRVAVPE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 SKALARKVSCKLSLRQPGEVNEDISQELMDSDSGNYLKRALQLSDRKNLVPRDEELCIYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_848 SKALARKVSCKLSLRQPGEVNEDISQELMDSDSGNYLKRALQLSDRKNLVPRDEELCIYE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 NKVTPLHFLVAQGSVEQVRLLLAHEVDVDCQTASGYTPLLIAAQDQQPDLCALLLAHGAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_848 NKVTPLHFLVAQGSVEQVRLLLAHEVDVDCQTASGYTPLLIAAQDQQPDLCALLLAHGAD
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 ANRVDEDGWAPLHFAAQNGDDGTARLLLDHGACVDAQEREGWTPLHLAAQNNFENVARLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_848 ANRVDEDGWAPLHFAAQNGDDGTARLLLDHGACVDAQEREGWTPLHLAAQNNFENVARLL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 VSRQADPNLHEAEGKTPLHVAAYFGHVSLVKLLTSQGAELDAQQRNLRTPLHLAVERGKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_848 VSRQADPNLHEAEGKTPLHVAAYFGHVSLVKLLTSQGAELDAQQRNLRTPLHLAVERGKV
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 RAIQHLLKSGAVPDALDQSGYGPLHTAAARGKYLICKMLLRYGASLELPTHQGWTPLHLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_848 RAIQHLLKSGAVPDALDQSGYGPLHTAAARGKYLICKMLLRYGASLELPTHQGWTPLHLA
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 AYKGHLEIIHLLAESHANMGALGAVNWTPLHLAARHGEEAVVSALLQCGADPNAAEQSGW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_848 AYKGHLEIIHLLAESHANMGALGAVNWTPLHLAARHGEEAVVSALLQCGADPNAAEQSGW
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 TPLHLAVQRSTFLSVINLLEHHANVHARNKVGWTPAHLAALKGNTAILKVLVEAGAQLDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_848 TPLHLAVQRSTFLSVINLLEHHANVHARNKVGWTPAHLAALKGNTAILKVLVEAGAQLDV
670 680 690 700 710 720
730 740 750 760
pF1KE3 QDGVSCTPLQLALRSRKQGIMSFLEGKEPSVATLGGSKPGAEMEI
:::::::::::::::::::::::::::::::::::::::::::::
NP_848 QDGVSCTPLQLALRSRKQGIMSFLEGKEPSVATLGGSKPGAEMEI
730 740 750 760
>>XP_011541039 (OMIM: 608774) PREDICTED: ankyrin repeat (766 aa)
initn: 3407 init1: 2885 opt: 5111 Z-score: 1463.0 bits: 281.4 E(85289): 9.5e-75
Smith-Waterman score: 5111; 99.9% identity (99.9% similar) in 766 aa overlap (1-765:1-766)
10 20 30 40 50 60
pF1KE3 MAADPTELRLGSLPVFTRDDFEGDWRLVASGGFSQVFQARHRRWRTEYAIKCAPCLPPDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAADPTELRLGSLPVFTRDDFEGDWRLVASGGFSQVFQARHRRWRTEYAIKCAPCLPPDA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 ASSDVNYLIEEAAKMKKIKFQHIVSIYGVCKQPLGIVMEFMANGSLEKVLSTHSLCWKLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASSDVNYLIEEAAKMKKIKFQHIVSIYGVCKQPLGIVMEFMANGSLEKVLSTHSLCWKLR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 FRIIHETSLAMNFLHSIKPPLLHLDLKPGNILLDSNMHVKISDFGLSKWMEQSTRMQYIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FRIIHETSLAMNFLHSIKPPLLHLDLKPGNILLDSNMHVKISDFGLSKWMEQSTRMQYIE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 RSALRGMLSYIPPEMFLESNKAPGPKYDVYSFAIVIWELLTQKKPYSGFNMMMIIIRVAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RSALRGMLSYIPPEMFLESNKAPGPKYDVYSFAIVIWELLTQKKPYSGFNMMMIIIRVAA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 GMRPSLQPVSDQWPSEAQQMVDLMKRCWDQDPKKRPCFLDITIETDILLSLLQSRVAVPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GMRPSLQPVSDQWPSEAQQMVDLMKRCWDQDPKKRPCFLDITIETDILLSLLQSRVAVPE
250 260 270 280 290 300
310 320 330 340 350
pF1KE3 SKALARKVSCKLSLRQPGEVNEDISQELMDS-DSGNYLKRALQLSDRKNLVPRDEELCIY
::::::::::::::::::::::::::::::: ::::::::::::::::::::::::::::
XP_011 SKALARKVSCKLSLRQPGEVNEDISQELMDSADSGNYLKRALQLSDRKNLVPRDEELCIY
310 320 330 340 350 360
360 370 380 390 400 410
pF1KE3 ENKVTPLHFLVAQGSVEQVRLLLAHEVDVDCQTASGYTPLLIAAQDQQPDLCALLLAHGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ENKVTPLHFLVAQGSVEQVRLLLAHEVDVDCQTASGYTPLLIAAQDQQPDLCALLLAHGA
370 380 390 400 410 420
420 430 440 450 460 470
pF1KE3 DANRVDEDGWAPLHFAAQNGDDGTARLLLDHGACVDAQEREGWTPLHLAAQNNFENVARL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DANRVDEDGWAPLHFAAQNGDDGTARLLLDHGACVDAQEREGWTPLHLAAQNNFENVARL
430 440 450 460 470 480
480 490 500 510 520 530
pF1KE3 LVSRQADPNLHEAEGKTPLHVAAYFGHVSLVKLLTSQGAELDAQQRNLRTPLHLAVERGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LVSRQADPNLHEAEGKTPLHVAAYFGHVSLVKLLTSQGAELDAQQRNLRTPLHLAVERGK
490 500 510 520 530 540
540 550 560 570 580 590
pF1KE3 VRAIQHLLKSGAVPDALDQSGYGPLHTAAARGKYLICKMLLRYGASLELPTHQGWTPLHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VRAIQHLLKSGAVPDALDQSGYGPLHTAAARGKYLICKMLLRYGASLELPTHQGWTPLHL
550 560 570 580 590 600
600 610 620 630 640 650
pF1KE3 AAYKGHLEIIHLLAESHANMGALGAVNWTPLHLAARHGEEAVVSALLQCGADPNAAEQSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AAYKGHLEIIHLLAESHANMGALGAVNWTPLHLAARHGEEAVVSALLQCGADPNAAEQSG
610 620 630 640 650 660
660 670 680 690 700 710
pF1KE3 WTPLHLAVQRSTFLSVINLLEHHANVHARNKVGWTPAHLAALKGNTAILKVLVEAGAQLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WTPLHLAVQRSTFLSVINLLEHHANVHARNKVGWTPAHLAALKGNTAILKVLVEAGAQLD
670 680 690 700 710 720
720 730 740 750 760
pF1KE3 VQDGVSCTPLQLALRSRKQGIMSFLEGKEPSVATLGGSKPGAEMEI
::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VQDGVSCTPLQLALRSRKQGIMSFLEGKEPSVATLGGSKPGAEMEI
730 740 750 760
>>XP_016872964 (OMIM: 608774) PREDICTED: ankyrin repeat (775 aa)
initn: 3602 init1: 3602 opt: 3602 Z-score: 1042.6 bits: 203.7 E(85289): 2.5e-51
Smith-Waterman score: 5093; 98.7% identity (98.7% similar) in 775 aa overlap (1-765:1-775)
10 20 30 40 50 60
pF1KE3 MAADPTELRLGSLPVFTRDDFEGDWRLVASGGFSQVFQARHRRWRTEYAIKCAPCLPPDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAADPTELRLGSLPVFTRDDFEGDWRLVASGGFSQVFQARHRRWRTEYAIKCAPCLPPDA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 ASSDVNYLIEEAAKMKKIKFQHIVSIYGVCKQPLGIVMEFMANGSLEKVLSTHSLCWKLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ASSDVNYLIEEAAKMKKIKFQHIVSIYGVCKQPLGIVMEFMANGSLEKVLSTHSLCWKLR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 FRIIHETSLAMNFLHSIKPPLLHLDLKPGNILLDSNMHVKISDFGLSKWMEQSTRMQYIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FRIIHETSLAMNFLHSIKPPLLHLDLKPGNILLDSNMHVKISDFGLSKWMEQSTRMQYIE
130 140 150 160 170 180
190 200 210 220 230
pF1KE3 RSALRGMLSYIPPEMFLESNKAPGPKYDVYSFAIVIWELLTQKKPYS----------GFN
::::::::::::::::::::::::::::::::::::::::::::::: :::
XP_016 RSALRGMLSYIPPEMFLESNKAPGPKYDVYSFAIVIWELLTQKKPYSELTSQLKERKGFN
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE3 MMMIIIRVAAGMRPSLQPVSDQWPSEAQQMVDLMKRCWDQDPKKRPCFLDITIETDILLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MMMIIIRVAAGMRPSLQPVSDQWPSEAQQMVDLMKRCWDQDPKKRPCFLDITIETDILLS
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE3 LLQSRVAVPESKALARKVSCKLSLRQPGEVNEDISQELMDSDSGNYLKRALQLSDRKNLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLQSRVAVPESKALARKVSCKLSLRQPGEVNEDISQELMDSDSGNYLKRALQLSDRKNLV
310 320 330 340 350 360
360 370 380 390 400 410
pF1KE3 PRDEELCIYENKVTPLHFLVAQGSVEQVRLLLAHEVDVDCQTASGYTPLLIAAQDQQPDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PRDEELCIYENKVTPLHFLVAQGSVEQVRLLLAHEVDVDCQTASGYTPLLIAAQDQQPDL
370 380 390 400 410 420
420 430 440 450 460 470
pF1KE3 CALLLAHGADANRVDEDGWAPLHFAAQNGDDGTARLLLDHGACVDAQEREGWTPLHLAAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CALLLAHGADANRVDEDGWAPLHFAAQNGDDGTARLLLDHGACVDAQEREGWTPLHLAAQ
430 440 450 460 470 480
480 490 500 510 520 530
pF1KE3 NNFENVARLLVSRQADPNLHEAEGKTPLHVAAYFGHVSLVKLLTSQGAELDAQQRNLRTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NNFENVARLLVSRQADPNLHEAEGKTPLHVAAYFGHVSLVKLLTSQGAELDAQQRNLRTP
490 500 510 520 530 540
540 550 560 570 580 590
pF1KE3 LHLAVERGKVRAIQHLLKSGAVPDALDQSGYGPLHTAAARGKYLICKMLLRYGASLELPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LHLAVERGKVRAIQHLLKSGAVPDALDQSGYGPLHTAAARGKYLICKMLLRYGASLELPT
550 560 570 580 590 600
600 610 620 630 640 650
pF1KE3 HQGWTPLHLAAYKGHLEIIHLLAESHANMGALGAVNWTPLHLAARHGEEAVVSALLQCGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HQGWTPLHLAAYKGHLEIIHLLAESHANMGALGAVNWTPLHLAARHGEEAVVSALLQCGA
610 620 630 640 650 660
660 670 680 690 700 710
pF1KE3 DPNAAEQSGWTPLHLAVQRSTFLSVINLLEHHANVHARNKVGWTPAHLAALKGNTAILKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DPNAAEQSGWTPLHLAVQRSTFLSVINLLEHHANVHARNKVGWTPAHLAALKGNTAILKV
670 680 690 700 710 720
720 730 740 750 760
pF1KE3 LVEAGAQLDVQDGVSCTPLQLALRSRKQGIMSFLEGKEPSVATLGGSKPGAEMEI
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LVEAGAQLDVQDGVSCTPLQLALRSRKQGIMSFLEGKEPSVATLGGSKPGAEMEI
730 740 750 760 770
>>XP_011541040 (OMIM: 608774) PREDICTED: ankyrin repeat (702 aa)
initn: 3899 init1: 2885 opt: 3590 Z-score: 1039.8 bits: 203.0 E(85289): 3.6e-51
Smith-Waterman score: 4568; 98.4% identity (98.4% similar) in 702 aa overlap (75-765:1-702)
50 60 70 80 90 100
pF1KE3 RTEYAIKCAPCLPPDAASSDVNYLIEEAAKMKKIKFQHIVSIYGVCKQPLGIVMEFMANG
::::::::::::::::::::::::::::::
XP_011 MKKIKFQHIVSIYGVCKQPLGIVMEFMANG
10 20 30
110 120 130 140 150 160
pF1KE3 SLEKVLSTHSLCWKLRFRIIHETSLAMNFLHSIKPPLLHLDLKPGNILLDSNMHVKISDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLEKVLSTHSLCWKLRFRIIHETSLAMNFLHSIKPPLLHLDLKPGNILLDSNMHVKISDF
40 50 60 70 80 90
170 180 190 200 210 220
pF1KE3 GLSKWMEQSTRMQYIERSALRGMLSYIPPEMFLESNKAPGPKYDVYSFAIVIWELLTQKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLSKWMEQSTRMQYIERSALRGMLSYIPPEMFLESNKAPGPKYDVYSFAIVIWELLTQKK
100 110 120 130 140 150
230 240 250 260 270
pF1KE3 PYS----------GFNMMMIIIRVAAGMRPSLQPVSDQWPSEAQQMVDLMKRCWDQDPKK
::: :::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PYSELTSQLKERKGFNMMMIIIRVAAGMRPSLQPVSDQWPSEAQQMVDLMKRCWDQDPKK
160 170 180 190 200 210
280 290 300 310 320 330
pF1KE3 RPCFLDITIETDILLSLLQSRVAVPESKALARKVSCKLSLRQPGEVNEDISQELMDS-DS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::
XP_011 RPCFLDITIETDILLSLLQSRVAVPESKALARKVSCKLSLRQPGEVNEDISQELMDSADS
220 230 240 250 260 270
340 350 360 370 380 390
pF1KE3 GNYLKRALQLSDRKNLVPRDEELCIYENKVTPLHFLVAQGSVEQVRLLLAHEVDVDCQTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GNYLKRALQLSDRKNLVPRDEELCIYENKVTPLHFLVAQGSVEQVRLLLAHEVDVDCQTA
280 290 300 310 320 330
400 410 420 430 440 450
pF1KE3 SGYTPLLIAAQDQQPDLCALLLAHGADANRVDEDGWAPLHFAAQNGDDGTARLLLDHGAC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SGYTPLLIAAQDQQPDLCALLLAHGADANRVDEDGWAPLHFAAQNGDDGTARLLLDHGAC
340 350 360 370 380 390
460 470 480 490 500 510
pF1KE3 VDAQEREGWTPLHLAAQNNFENVARLLVSRQADPNLHEAEGKTPLHVAAYFGHVSLVKLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VDAQEREGWTPLHLAAQNNFENVARLLVSRQADPNLHEAEGKTPLHVAAYFGHVSLVKLL
400 410 420 430 440 450
520 530 540 550 560 570
pF1KE3 TSQGAELDAQQRNLRTPLHLAVERGKVRAIQHLLKSGAVPDALDQSGYGPLHTAAARGKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TSQGAELDAQQRNLRTPLHLAVERGKVRAIQHLLKSGAVPDALDQSGYGPLHTAAARGKY
460 470 480 490 500 510
580 590 600 610 620 630
pF1KE3 LICKMLLRYGASLELPTHQGWTPLHLAAYKGHLEIIHLLAESHANMGALGAVNWTPLHLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LICKMLLRYGASLELPTHQGWTPLHLAAYKGHLEIIHLLAESHANMGALGAVNWTPLHLA
520 530 540 550 560 570
640 650 660 670 680 690
pF1KE3 ARHGEEAVVSALLQCGADPNAAEQSGWTPLHLAVQRSTFLSVINLLEHHANVHARNKVGW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ARHGEEAVVSALLQCGADPNAAEQSGWTPLHLAVQRSTFLSVINLLEHHANVHARNKVGW
580 590 600 610 620 630
700 710 720 730 740 750
pF1KE3 TPAHLAALKGNTAILKVLVEAGAQLDVQDGVSCTPLQLALRSRKQGIMSFLEGKEPSVAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TPAHLAALKGNTAILKVLVEAGAQLDVQDGVSCTPLQLALRSRKQGIMSFLEGKEPSVAT
640 650 660 670 680 690
760
pF1KE3 LGGSKPGAEMEI
::::::::::::
XP_011 LGGSKPGAEMEI
700
>>XP_011541038 (OMIM: 608774) PREDICTED: ankyrin repeat (776 aa)
initn: 4412 init1: 2885 opt: 3590 Z-score: 1039.2 bits: 203.0 E(85289): 3.8e-51
Smith-Waterman score: 5081; 98.6% identity (98.6% similar) in 776 aa overlap (1-765:1-776)
10 20 30 40 50 60
pF1KE3 MAADPTELRLGSLPVFTRDDFEGDWRLVASGGFSQVFQARHRRWRTEYAIKCAPCLPPDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAADPTELRLGSLPVFTRDDFEGDWRLVASGGFSQVFQARHRRWRTEYAIKCAPCLPPDA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 ASSDVNYLIEEAAKMKKIKFQHIVSIYGVCKQPLGIVMEFMANGSLEKVLSTHSLCWKLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASSDVNYLIEEAAKMKKIKFQHIVSIYGVCKQPLGIVMEFMANGSLEKVLSTHSLCWKLR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 FRIIHETSLAMNFLHSIKPPLLHLDLKPGNILLDSNMHVKISDFGLSKWMEQSTRMQYIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FRIIHETSLAMNFLHSIKPPLLHLDLKPGNILLDSNMHVKISDFGLSKWMEQSTRMQYIE
130 140 150 160 170 180
190 200 210 220 230
pF1KE3 RSALRGMLSYIPPEMFLESNKAPGPKYDVYSFAIVIWELLTQKKPYS----------GFN
::::::::::::::::::::::::::::::::::::::::::::::: :::
XP_011 RSALRGMLSYIPPEMFLESNKAPGPKYDVYSFAIVIWELLTQKKPYSELTSQLKERKGFN
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE3 MMMIIIRVAAGMRPSLQPVSDQWPSEAQQMVDLMKRCWDQDPKKRPCFLDITIETDILLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MMMIIIRVAAGMRPSLQPVSDQWPSEAQQMVDLMKRCWDQDPKKRPCFLDITIETDILLS
250 260 270 280 290 300
300 310 320 330 340
pF1KE3 LLQSRVAVPESKALARKVSCKLSLRQPGEVNEDISQELMDS-DSGNYLKRALQLSDRKNL
::::::::::::::::::::::::::::::::::::::::: ::::::::::::::::::
XP_011 LLQSRVAVPESKALARKVSCKLSLRQPGEVNEDISQELMDSADSGNYLKRALQLSDRKNL
310 320 330 340 350 360
350 360 370 380 390 400
pF1KE3 VPRDEELCIYENKVTPLHFLVAQGSVEQVRLLLAHEVDVDCQTASGYTPLLIAAQDQQPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VPRDEELCIYENKVTPLHFLVAQGSVEQVRLLLAHEVDVDCQTASGYTPLLIAAQDQQPD
370 380 390 400 410 420
410 420 430 440 450 460
pF1KE3 LCALLLAHGADANRVDEDGWAPLHFAAQNGDDGTARLLLDHGACVDAQEREGWTPLHLAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LCALLLAHGADANRVDEDGWAPLHFAAQNGDDGTARLLLDHGACVDAQEREGWTPLHLAA
430 440 450 460 470 480
470 480 490 500 510 520
pF1KE3 QNNFENVARLLVSRQADPNLHEAEGKTPLHVAAYFGHVSLVKLLTSQGAELDAQQRNLRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QNNFENVARLLVSRQADPNLHEAEGKTPLHVAAYFGHVSLVKLLTSQGAELDAQQRNLRT
490 500 510 520 530 540
530 540 550 560 570 580
pF1KE3 PLHLAVERGKVRAIQHLLKSGAVPDALDQSGYGPLHTAAARGKYLICKMLLRYGASLELP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PLHLAVERGKVRAIQHLLKSGAVPDALDQSGYGPLHTAAARGKYLICKMLLRYGASLELP
550 560 570 580 590 600
590 600 610 620 630 640
pF1KE3 THQGWTPLHLAAYKGHLEIIHLLAESHANMGALGAVNWTPLHLAARHGEEAVVSALLQCG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 THQGWTPLHLAAYKGHLEIIHLLAESHANMGALGAVNWTPLHLAARHGEEAVVSALLQCG
610 620 630 640 650 660
650 660 670 680 690 700
pF1KE3 ADPNAAEQSGWTPLHLAVQRSTFLSVINLLEHHANVHARNKVGWTPAHLAALKGNTAILK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ADPNAAEQSGWTPLHLAVQRSTFLSVINLLEHHANVHARNKVGWTPAHLAALKGNTAILK
670 680 690 700 710 720
710 720 730 740 750 760
pF1KE3 VLVEAGAQLDVQDGVSCTPLQLALRSRKQGIMSFLEGKEPSVATLGGSKPGAEMEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLVEAGAQLDVQDGVSCTPLQLALRSRKQGIMSFLEGKEPSVATLGGSKPGAEMEI
730 740 750 760 770
>>NP_065690 (OMIM: 263650,605706) receptor-interacting s (784 aa)
initn: 1212 init1: 605 opt: 920 Z-score: 295.4 bits: 65.4 E(85289): 1e-09
Smith-Waterman score: 1507; 38.6% identity (64.4% similar) in 759 aa overlap (10-686:11-762)
10 20 30 40 50
pF1KE3 MAADPTELRLGSLPVFTRDDFEGDWRLVASGGFSQVFQARHRRWRTEYAIKCAPCLPPD
:. : .: .: : :. :.::::.::...:: .:.: ::::.: : :
NP_065 MEGDGGTPWALALLRTFDAGEFTG-WEKVGSGGFGQVYKVRHVHWKTWLAIKCSPSLHVD
10 20 30 40 50
60 70 80 90 100 110
pF1KE3 AASSDVNYLIEEAAKMKKIKFQHIVSIYGVCKQPLGIVMEFMANGSLEKVLSTHSLCWKL
. . :.::: ::. ::..:. .::.:..:.:.:::.: .:::::.:... : : :
NP_065 --DRERMELLEEAKKMEMAKFRYILPVYGICREPVGLVMEYMETGSLEKLLASEPLPWDL
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE3 RFRIIHETSLAMNFLHSIKPPLLHLDLKPGNILLDSNMHVKISDFGLSKWMEQSTRMQYI
::::::::...::::: . ::::::::::.:::::...:::::::::.: . .. . .
NP_065 RFRIIHETAVGMNFLHCMAPPLLHLDLKPANILLDAHYHVKISDFGLAK-CNGLSHSHDL
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE3 ERSALRGMLSYIPPEMFLESNKAPGPKYDVYSFAIVIWELLTQKKPYSGF-NMMMIIIRV
..: : ..:.::: . :... :.:::::::::: .::::::.. :.. :...:
NP_065 SMDGLFGTIAYLPPERIREKSRLFDTKHDVYSFAIVIWGVLTQKKPFADEKNILHIMVKV
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE3 AAGMRPSLQPVSDQWPSEAQQMVDLMKRCWDQDPKKRPCFLDITIETDILLSLLQSRV--
. : :: : :: : .... ::.:::. ::. :: : .:: ::. : ...:
NP_065 VKGHRPELPPVCRARPRACSHLIRLMQRCWQGDPRVRPTFQEITSETEDLCEKPDDEVKE
240 250 260 270 280 290
300 310 320
pF1KE3 --------AVPESK-----ALARKVSC-------KLS--LRQ-----------PGEVNED
. :: . : ...: .:: : : : :....
NP_065 TAHDLDVKSPPEPRSEVVPARLKRASAPTFDNDYSLSELLSQLDSGVSQAVEGPEELSRS
300 310 320 330 340 350
330 340 350
pF1KE3 ISQ-ELMDSDSGNYL------------KRALQLS---------------DRKNLV-----
:. .: .: ::. : . .:.:: ..:.::
NP_065 SSESKLPSSGSGKRLSGVSSVDSAFSSRGSLSLSFEREPSTSDLGTTDVQKKKLVDAIVS
360 370 380 390 400 410
360 370 380 390
pF1KE3 -----------PRDEELCIYENKVTPLHFLVAQGSVEQVRLLLAHEVDVDCQTASGYTPL
:.: .: . .. .. ::. : :. : .. :: .... . .. : :::
NP_065 GDTSKLMKILQPQDVDLAL-DSGASLLHLAVEAGQEECAKWLLLNNANPNLSNRRGSTPL
420 430 440 450 460 470
400 410 420 430 440 450
pF1KE3 LIAAQDQQPDLCALLLAHGADANRVDEDGWAPLHFAAQNGDDGTARLLLDHGACVDAQER
.:.. . . ::::. ..: ::: :. :::::::::....::::...: :. .
NP_065 HMAVERRVRGVVELLLARKISVNAKDEDQWTALHFAAQNGDESSTRLLLEKNASVNEVDF
480 490 500 510 520 530
460 470 480 490 500 510
pF1KE3 EGWTPLHLAAQNNFENVARLLVSRQADPNLHEAEGKTPLHVAAYFGHVSLVKLLTSQ-GA
:: ::.:.: :.. ::..:.:. : .: .:. .. ::: ::. ::. .::::..: :.
NP_065 EGRTPMHVACQHGQENIVRILLRRGVDVSLQGKDAWLPLHYAAWQGHLPIVKLLAKQPGV
540 550 560 570 580 590
520 530 540 550 560 570
pF1KE3 ELDAQQRNLRTPLHLAVERGKVRAIQHLLKSGAVPDALDQSGYGPLHTAAARGKYLICKM
..:: . :::::::..::. :. . :. . .. . . :::.:: :. ..
NP_065 SVNAQTLDGRTPLHLAAQRGHYRVARILIDLCSDVNVCSLLAQTPLHVAAETGHTSTARL
600 610 620 630 640 650
580 590 600 610 620 630
pF1KE3 LLRYGASLELPTHQGWTPLHLAAYKGHLEIIHLLAESHANMGALGAVNWTPLHLAARHGE
::. ::. : : .:.: ::::: .::: ..::.: .:.. : : .: : ::::: ::.
NP_065 LLHRGAGKEAMTSDGYTALHLAARNGHLATVKLLVEEKADVLARGPLNQTALHLAAAHGH
660 670 680 690 700 710
640 650 660 670 680 690
pF1KE3 EAVVSALLQCGADP-NAAEQSGWTPLHLAVQRSTFLSVINLLEHHANVHARNKVGWTPAH
:: :. .:: . ...: . ::::.: .: .::.: :...
NP_065 SEVVEELV--SADVIDLFDEQGLSALHLAAQGRHAQTVETLLRHGAHINLQSLKFQGGHG
720 730 740 750 760 770
700 710 720 730 740 750
pF1KE3 LAALKGNTAILKVLVEAGAQLDVQDGVSCTPLQLALRSRKQGIMSFLEGKEPSVATLGGS
NP_065 PAATLLRRSKT
780
>>XP_016863601 (OMIM: 106410,600919) PREDICTED: ankyrin- (1689 aa)
initn: 1514 init1: 798 opt: 812 Z-score: 261.2 bits: 60.2 E(85289): 8.3e-08
Smith-Waterman score: 812; 36.4% identity (67.6% similar) in 401 aa overlap (361-759:236-636)
340 350 360 370 380 390
pF1KE3 SDSGNYLKRALQLSDRKNLVPRDEELCIYENKVTPLHFLVAQGSVEQVRLLLAHEVDVDC
: .:::: .:....:.::: . ..:
XP_016 TPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLLLDRGGQIDA
210 220 230 240 250 260
400 410 420 430 440 450
pF1KE3 QTASGYTPLLIAAQDQQPDLCALLLAHGADANRVDEDGWAPLHFAAQNGDDGTARLLLDH
.: .: ::: ::.. . .. ::: .:: ..: .:::.:::. .. ::.:
XP_016 KTRDGLTPLHCAARSGHDQVVELLLERGAPLLARTKNGLSPLHMAAQGDHVECVKHLLQH
270 280 290 300 310 320
460 470 480 490 500 510
pF1KE3 GACVDAQEREGWTPLHLAAQNNFENVARLLVSRQADPNLHEAEGKTPLHVAAYFGHVSLV
: :: . : ::.::. . :..::....:.:: . .:.: ::.:: :.: .:
XP_016 KAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALRGETALHMAARAGQVEVV
330 340 350 360 370 380
520 530 540 550 560 570
pF1KE3 KLLTSQGAELDAQQRNLRTPLHLAVERGKVRAIQHLLKSGAVPDALDQSGYGPLHTAAAR
. : .:: .::. :. .::::.: . ::.. .: ::. : ::: .:: ::: .: .
XP_016 RCLLRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISARE
390 400 410 420 430 440
580 590 600 610 620 630
pF1KE3 GKYLICKMLLRYGASLELPTHQGWTPLHLAAYKGHLEIIHLLAESHANMGALGAVNWTPL
:. . ..::. ::. : :..:.::::.:: : :.. .:: . .: . : . :::
XP_016 GQVDVASVLLEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLLLQRRAAADSAGKNGLTPL
450 460 470 480 490 500
640 650 660 670 680 690
pF1KE3 HLAARHGEEAVVSALLQCGADPNAAEQSGWTPLHLAVQRSTFLSVINLLEHHANVHARNK
:.::.. .. :. ::. ::.:.:. ..:.::::.:.... . . .::.. :... .:
XP_016 HVAAHYDNQKVALLLLEKGASPHATAKNGYTPLHIAAKKNQMQIASTLLNYGAETNIVTK
510 520 530 540 550 560
700 710 720 730 740
pF1KE3 VGWTPAHLAALKGNTAILKVLVEAGAQLDVQDGVSCTPLQLALRSRKQGIMSFL--EGKE
: :: :::. .:.: .. .:.. ::.. .. . : :.:: . : .. ..: .: .
XP_016 QGVTPLHLASQEGHTDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGAD
570 580 590 600 610 620
750 760
pF1KE3 PSVATLGGSKPGAEMEI
.. : : :
XP_016 QDAHTKLGYTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTHIINVL
630 640 650 660 670 680
>>XP_016863597 (OMIM: 106410,600919) PREDICTED: ankyrin- (1772 aa)
initn: 1513 init1: 798 opt: 812 Z-score: 260.9 bits: 60.2 E(85289): 8.5e-08
Smith-Waterman score: 817; 33.9% identity (65.3% similar) in 478 aa overlap (293-759:188-665)
270 280 290 300 310 320
pF1KE3 LMKRCWDQDPKKRPCFLDITIETDILLSLLQSRVAVPESKALARKVSCK-LSLRQPGEVN
...: .: . ::: . : .: .. :
XP_016 TATEDGFTPLAVALQQGHNQAVAILLENDTKGKVRLPALHIAARKDDTKSAALLLQNDHN
160 170 180 190 200 210
330 340 350 360 370
pF1KE3 EDISQELM---DSDSG-NYLKRALQLSDRKN---LVPRDEEL-CIYENKVTPLHFLVAQG
:.....: ..:: . :. : . .. . :. : . .: .:::: .:
XP_016 ADVQSKMMVNRTTESGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRG
220 230 240 250 260 270
380 390 400 410 420 430
pF1KE3 SVEQVRLLLAHEVDVDCQTASGYTPLLIAAQDQQPDLCALLLAHGADANRVDEDGWAPLH
....:.::: . ..: .: .: ::: ::.. . .. ::: .:: ..: .:::
XP_016 NTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLLERGAPLLARTKNGLSPLH
280 290 300 310 320 330
440 450 460 470 480 490
pF1KE3 FAAQNGDDGTARLLLDHGACVDAQEREGWTPLHLAAQNNFENVARLLVSRQADPNLHEAE
.:::. .. ::.: : :: . : ::.::. . :..::....:.:: . .
XP_016 MAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALR
340 350 360 370 380 390
500 510 520 530 540 550
pF1KE3 GKTPLHVAAYFGHVSLVKLLTSQGAELDAQQRNLRTPLHLAVERGKVRAIQHLLKSGAVP
:.: ::.:: :.: .:. : .:: .::. :. .::::.: . ::.. .: ::. : :
XP_016 GETALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHP
400 410 420 430 440 450
560 570 580 590 600 610
pF1KE3 DALDQSGYGPLHTAAARGKYLICKMLLRYGASLELPTHQGWTPLHLAAYKGHLEIIHLLA
:: .:: ::: .: .:. . ..::. ::. : :..:.::::.:: : :.. .::
XP_016 DAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLLL
460 470 480 490 500 510
620 630 640 650 660 670
pF1KE3 ESHANMGALGAVNWTPLHLAARHGEEAVVSALLQCGADPNAAEQSGWTPLHLAVQRSTFL
. .: . : . ::::.::.. .. :. ::. ::.:.:. ..:.::::.:.... .
XP_016 QRRAAADSAGKNGLTPLHVAAHYDNQKVALLLLEKGASPHATAKNGYTPLHIAAKKNQMQ
520 530 540 550 560 570
680 690 700 710 720 730
pF1KE3 SVINLLEHHANVHARNKVGWTPAHLAALKGNTAILKVLVEAGAQLDVQDGVSCTPLQLAL
. .::.. :... .: : :: :::. .:.: .. .:.. ::.. .. . : :.::
XP_016 IASTLLNYGAETNIVTKQGVTPLHLASQEGHTDMVTLLLDKGANIHMSTKSGLTSLHLAA
580 590 600 610 620 630
740 750 760
pF1KE3 RSRKQGIMSFL--EGKEPSVATLGGSKPGAEMEI
. : .. ..: .: . .. : : :
XP_016 QEDKVNVADILTKHGADQDAHTKLGYTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYT
640 650 660 670 680 690
>>XP_016871638 (OMIM: 600465,615493) PREDICTED: ankyrin- (1720 aa)
initn: 2244 init1: 796 opt: 811 Z-score: 260.8 bits: 60.2 E(85289): 8.7e-08
Smith-Waterman score: 811; 35.7% identity (70.2% similar) in 403 aa overlap (360-759:315-716)
330 340 350 360 370 380
pF1KE3 DSDSGNYLKRALQLSDRKNLVPRDEELCIYENKVTPLHFLVAQGS-VEQVRLLLAHEVDV
.: ..::: ...::. .. :.::: :.: :
XP_016 LTPLHCGARSGHEQVVEMLLDRAAPILSKTKNGLSPLH-MATQGDHLNCVQLLLQHNVPV
290 300 310 320 330 340
390 400 410 420 430 440
pF1KE3 DCQTASGYTPLLIAAQDQQPDLCALLLAHGADANRVDEDGWAPLHFAAQNGDDGTARLLL
: : . : : .::. . . .:: . :. : .:..:::.: ... . .:::
XP_016 DDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKALNGFTPLHIACKKNRIKVMELLL
350 360 370 380 390 400
450 460 470 480 490 500
pF1KE3 DHGACVDAQEREGWTPLHLAAQNNFENVARLLVSRQADPNLHEAEGKTPLHVAAYFGHVS
::: ..: . : ::.:.:: . :.. :. . :.:: ...:.: ::.:: :..
XP_016 KHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAE
410 420 430 440 450 460
510 520 530 540 550 560
pF1KE3 LVKLLTSQGAELDAQQRNLRTPLHLAVERGKVRAIQHLLKSGAVPDALDQSGYGPLHTAA
.:. :...::...:. .. .::::.... ::. .:.::..:: :.: ::: ::: .:
XP_016 VVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSA
470 480 490 500 510 520
570 580 590 600 610 620
pF1KE3 ARGKYLICKMLLRYGASLELPTHQGWTPLHLAAYKGHLEIIHLLAESHANMGALGAVNWT
.:. . .:: .:::: . :..:.::::.:: :.::. .:: .. :. : : . :
XP_016 REGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVANLLLQKSASPDAAGKSGLT
530 540 550 560 570 580
630 640 650 660 670 680
pF1KE3 PLHLAARHGEEAVVSALLQCGADPNAAEQSGWTPLHLAVQRSTFLSVINLLEHHANVHAR
:::.::.. .. :. ::. ::.:.:: ..:.::::.:.... . . .:::. :...:
XP_016 PLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAV
590 600 610 620 630 640
690 700 710 720 730 740
pF1KE3 NKVGWTPAHLAALKGNTAILKVLVEAGAQLDVQDGVSCTPLQLALRSRKQGIMSFL--EG
.. : . .:::: .:.. ....:. .:...... . :::.:: . . .. : .:
XP_016 TRQGIASVHLAAQEGHVDMVSLLLGRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQG
650 660 670 680 690 700
750 760
pF1KE3 KEPSVATLGGSKPGAEMEI
. .. : : :
XP_016 AHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIIN
710 720 730 740 750 760
>>XP_016871637 (OMIM: 600465,615493) PREDICTED: ankyrin- (1725 aa)
initn: 2244 init1: 796 opt: 811 Z-score: 260.8 bits: 60.2 E(85289): 8.7e-08
Smith-Waterman score: 811; 35.7% identity (70.2% similar) in 403 aa overlap (360-759:315-716)
330 340 350 360 370 380
pF1KE3 DSDSGNYLKRALQLSDRKNLVPRDEELCIYENKVTPLHFLVAQGS-VEQVRLLLAHEVDV
.: ..::: ...::. .. :.::: :.: :
XP_016 LTPLHCGARSGHEQVVEMLLDRAAPILSKTKNGLSPLH-MATQGDHLNCVQLLLQHNVPV
290 300 310 320 330 340
390 400 410 420 430 440
pF1KE3 DCQTASGYTPLLIAAQDQQPDLCALLLAHGADANRVDEDGWAPLHFAAQNGDDGTARLLL
: : . : : .::. . . .:: . :. : .:..:::.: ... . .:::
XP_016 DDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKALNGFTPLHIACKKNRIKVMELLL
350 360 370 380 390 400
450 460 470 480 490 500
pF1KE3 DHGACVDAQEREGWTPLHLAAQNNFENVARLLVSRQADPNLHEAEGKTPLHVAAYFGHVS
::: ..: . : ::.:.:: . :.. :. . :.:: ...:.: ::.:: :..
XP_016 KHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAE
410 420 430 440 450 460
510 520 530 540 550 560
pF1KE3 LVKLLTSQGAELDAQQRNLRTPLHLAVERGKVRAIQHLLKSGAVPDALDQSGYGPLHTAA
.:. :...::...:. .. .::::.... ::. .:.::..:: :.: ::: ::: .:
XP_016 VVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSA
470 480 490 500 510 520
570 580 590 600 610 620
pF1KE3 ARGKYLICKMLLRYGASLELPTHQGWTPLHLAAYKGHLEIIHLLAESHANMGALGAVNWT
.:. . .:: .:::: . :..:.::::.:: :.::. .:: .. :. : : . :
XP_016 REGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVANLLLQKSASPDAAGKSGLT
530 540 550 560 570 580
630 640 650 660 670 680
pF1KE3 PLHLAARHGEEAVVSALLQCGADPNAAEQSGWTPLHLAVQRSTFLSVINLLEHHANVHAR
:::.::.. .. :. ::. ::.:.:: ..:.::::.:.... . . .:::. :...:
XP_016 PLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAV
590 600 610 620 630 640
690 700 710 720 730 740
pF1KE3 NKVGWTPAHLAALKGNTAILKVLVEAGAQLDVQDGVSCTPLQLALRSRKQGIMSFL--EG
.. : . .:::: .:.. ....:. .:...... . :::.:: . . .. : .:
XP_016 TRQGIASVHLAAQEGHVDMVSLLLGRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQG
650 660 670 680 690 700
750 760
pF1KE3 KEPSVATLGGSKPGAEMEI
. .. : : :
XP_016 AHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIIN
710 720 730 740 750 760
765 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 18:33:46 2016 done: Mon Nov 7 18:33:47 2016
Total Scan time: 8.160 Total Display time: 0.130
Function used was FASTA [36.3.4 Apr, 2011]