Result of FASTA (ccds) for
pFN21AE3292
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3292, 763 aa
1>>>pF1KE3292 763 - 763 aa - 763 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 10.4924+/-0.00129; mu= -4.7028+/- 0.076
mean_var=328.3235+/-74.482, 0's: 0 Z-trim(109.1): 460 B-trim: 59 in 1/51
Lambda= 0.070782
statistics sampled from 10177 (10690) to 10177 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.666), E-opt: 0.2 (0.328), width: 16
Scan time: 3.240
The best scores are: opt bits E(32554)
CCDS42925.1 DYRK1A gene_id:1859|Hs108|chr21 ( 763) 5180 543.9 3.5e-154
CCDS13653.1 DYRK1A gene_id:1859|Hs108|chr21 ( 754) 4664 491.2 2.5e-138
CCDS42926.1 DYRK1A gene_id:1859|Hs108|chr21 ( 584) 3779 400.8 3.3e-111
CCDS13654.1 DYRK1A gene_id:1859|Hs108|chr21 ( 529) 3478 370.0 5.5e-102
CCDS12543.1 DYRK1B gene_id:9149|Hs108|chr19 ( 629) 2538 274.1 4.9e-73
CCDS12544.1 DYRK1B gene_id:9149|Hs108|chr19 ( 601) 2058 225.0 2.7e-58
CCDS46075.1 DYRK1B gene_id:9149|Hs108|chr19 ( 589) 2010 220.1 8e-57
CCDS31000.1 DYRK3 gene_id:8444|Hs108|chr1 ( 568) 972 114.1 6.3e-25
CCDS30999.1 DYRK3 gene_id:8444|Hs108|chr1 ( 588) 972 114.1 6.5e-25
CCDS8979.1 DYRK2 gene_id:8445|Hs108|chr12 ( 528) 963 113.2 1.1e-24
CCDS8978.1 DYRK2 gene_id:8445|Hs108|chr12 ( 601) 963 113.2 1.2e-24
CCDS8530.1 DYRK4 gene_id:8798|Hs108|chr12 ( 520) 927 109.5 1.4e-23
CCDS75666.1 HIPK2 gene_id:28996|Hs108|chr7 (1171) 771 93.9 1.6e-18
CCDS75667.1 HIPK2 gene_id:28996|Hs108|chr7 (1198) 769 93.7 1.9e-18
CCDS868.1 HIPK1 gene_id:204851|Hs108|chr1 (1075) 765 93.2 2.3e-18
CCDS867.1 HIPK1 gene_id:204851|Hs108|chr1 (1210) 765 93.2 2.6e-18
CCDS41634.1 HIPK3 gene_id:10114|Hs108|chr11 (1194) 746 91.3 9.7e-18
CCDS7884.1 HIPK3 gene_id:10114|Hs108|chr11 (1215) 746 91.3 9.8e-18
CCDS12555.1 HIPK4 gene_id:147746|Hs108|chr19 ( 616) 645 80.7 7.6e-15
CCDS4488.1 PRPF4B gene_id:8899|Hs108|chr6 (1007) 616 78.0 8.5e-14
>>CCDS42925.1 DYRK1A gene_id:1859|Hs108|chr21 (763 aa)
initn: 5180 init1: 5180 opt: 5180 Z-score: 2881.6 bits: 543.9 E(32554): 3.5e-154
Smith-Waterman score: 5180; 100.0% identity (100.0% similar) in 763 aa overlap (1-763:1-763)
10 20 30 40 50 60
pF1KE3 MHTGGETSACKPSSVRLAPSFSFHAAGLQMAGQMPHSHQYSDRRQPNISDQQVSALSYSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 MHTGGETSACKPSSVRLAPSFSFHAAGLQMAGQMPHSHQYSDRRQPNISDQQVSALSYSD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 QIQQPLTNQVMPDIVMLQRRMPQTFRDPATAPLRKLSVDLIKTYKHINEVYYAKKKRRHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 QIQQPLTNQVMPDIVMLQRRMPQTFRDPATAPLRKLSVDLIKTYKHINEVYYAKKKRRHQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 QGQGDDSSHKKERKVYNDGYDDDNYDYIVKNGEKWMDRYEIDSLIGKGSFGQVVKAYDRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 QGQGDDSSHKKERKVYNDGYDDDNYDYIVKNGEKWMDRYEIDSLIGKGSFGQVVKAYDRV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 EQEWVAIKIIKNKKAFLNQAQIEVRLLELMNKHDTEMKYYIVHLKRHFMFRNHLCLVFEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 EQEWVAIKIIKNKKAFLNQAQIEVRLLELMNKHDTEMKYYIVHLKRHFMFRNHLCLVFEM
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 LSYNLYDLLRNTNFRGVSLNLTRKFAQQMCTALLFLATPELSIIHCDLKPENILLCNPKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 LSYNLYDLLRNTNFRGVSLNLTRKFAQQMCTALLFLATPELSIIHCDLKPENILLCNPKR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 SAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGMPYDLAIDMWSLGCILVEMHTGEPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 SAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGMPYDLAIDMWSLGCILVEMHTGEPL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 FSGANEVDQMNKIVEVLGIPPAHILDQAPKARKFFEKLPDGTWNLKKTKDGKREYKPPGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 FSGANEVDQMNKIVEVLGIPPAHILDQAPKARKFFEKLPDGTWNLKKTKDGKREYKPPGT
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 RKLHNILGVETGGPGGRRAGESGHTVADYLKFKDLILRMLDYDPKTRIQPYYALQHSFFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 RKLHNILGVETGGPGGRRAGESGHTVADYLKFKDLILRMLDYDPKTRIQPYYALQHSFFK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 KTADEGTNTSNSVSTSPAMEQSQSSGTTSSTSSSSGGSSGTSNSGRARSDPTHQHRHSGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 KTADEGTNTSNSVSTSPAMEQSQSSGTTSSTSSSSGGSSGTSNSGRARSDPTHQHRHSGG
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE3 HFTAAVQAMDCETHSPQVRQQFPAPLGWSGTEAPTQVTVETHPVQETTFHVAPQQNALHH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 HFTAAVQAMDCETHSPQVRQQFPAPLGWSGTEAPTQVTVETHPVQETTFHVAPQQNALHH
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE3 HHGNSSHHHHHHHHHHHHHGQQALGNRTRPRVYNSPTNSSSTQDSMEVGHSHHSMTSLSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 HHGNSSHHHHHHHHHHHHHGQQALGNRTRPRVYNSPTNSSSTQDSMEVGHSHHSMTSLSS
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE3 STTSSSTSSSSTGNQGNQAYQNRPVAANTLDFGQNGAMDVNLTVYSNPRQETGIAGHPTY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 STTSSSTSSSSTGNQGNQAYQNRPVAANTLDFGQNGAMDVNLTVYSNPRQETGIAGHPTY
670 680 690 700 710 720
730 740 750 760
pF1KE3 QFSANTGPAHYMTEGHLTMRQGADREESPMTGVCVQQSPVASS
:::::::::::::::::::::::::::::::::::::::::::
CCDS42 QFSANTGPAHYMTEGHLTMRQGADREESPMTGVCVQQSPVASS
730 740 750 760
>>CCDS13653.1 DYRK1A gene_id:1859|Hs108|chr21 (754 aa)
initn: 4659 init1: 4659 opt: 4664 Z-score: 2596.9 bits: 491.2 E(32554): 2.5e-138
Smith-Waterman score: 5093; 98.8% identity (98.8% similar) in 763 aa overlap (1-763:1-754)
10 20 30 40 50 60
pF1KE3 MHTGGETSACKPSSVRLAPSFSFHAAGLQMAGQMPHSHQYSDRRQPNISDQQVSALSYSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 MHTGGETSACKPSSVRLAPSFSFHAAGLQMAGQMPHSHQYSDRRQPNISDQQVSALSYSD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 QIQQPLTNQVMPDIVMLQRRMPQTFRDPATAPLRKLSVDLIKTYKHINEVYYAKKKRRHQ
::::::::: ::::::::::::::::::::::::::::::::::::::::::
CCDS13 QIQQPLTNQ---------RRMPQTFRDPATAPLRKLSVDLIKTYKHINEVYYAKKKRRHQ
70 80 90 100 110
130 140 150 160 170 180
pF1KE3 QGQGDDSSHKKERKVYNDGYDDDNYDYIVKNGEKWMDRYEIDSLIGKGSFGQVVKAYDRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 QGQGDDSSHKKERKVYNDGYDDDNYDYIVKNGEKWMDRYEIDSLIGKGSFGQVVKAYDRV
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE3 EQEWVAIKIIKNKKAFLNQAQIEVRLLELMNKHDTEMKYYIVHLKRHFMFRNHLCLVFEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 EQEWVAIKIIKNKKAFLNQAQIEVRLLELMNKHDTEMKYYIVHLKRHFMFRNHLCLVFEM
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE3 LSYNLYDLLRNTNFRGVSLNLTRKFAQQMCTALLFLATPELSIIHCDLKPENILLCNPKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 LSYNLYDLLRNTNFRGVSLNLTRKFAQQMCTALLFLATPELSIIHCDLKPENILLCNPKR
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE3 SAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGMPYDLAIDMWSLGCILVEMHTGEPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 SAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGMPYDLAIDMWSLGCILVEMHTGEPL
300 310 320 330 340 350
370 380 390 400 410 420
pF1KE3 FSGANEVDQMNKIVEVLGIPPAHILDQAPKARKFFEKLPDGTWNLKKTKDGKREYKPPGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 FSGANEVDQMNKIVEVLGIPPAHILDQAPKARKFFEKLPDGTWNLKKTKDGKREYKPPGT
360 370 380 390 400 410
430 440 450 460 470 480
pF1KE3 RKLHNILGVETGGPGGRRAGESGHTVADYLKFKDLILRMLDYDPKTRIQPYYALQHSFFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 RKLHNILGVETGGPGGRRAGESGHTVADYLKFKDLILRMLDYDPKTRIQPYYALQHSFFK
420 430 440 450 460 470
490 500 510 520 530 540
pF1KE3 KTADEGTNTSNSVSTSPAMEQSQSSGTTSSTSSSSGGSSGTSNSGRARSDPTHQHRHSGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 KTADEGTNTSNSVSTSPAMEQSQSSGTTSSTSSSSGGSSGTSNSGRARSDPTHQHRHSGG
480 490 500 510 520 530
550 560 570 580 590 600
pF1KE3 HFTAAVQAMDCETHSPQVRQQFPAPLGWSGTEAPTQVTVETHPVQETTFHVAPQQNALHH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 HFTAAVQAMDCETHSPQVRQQFPAPLGWSGTEAPTQVTVETHPVQETTFHVAPQQNALHH
540 550 560 570 580 590
610 620 630 640 650 660
pF1KE3 HHGNSSHHHHHHHHHHHHHGQQALGNRTRPRVYNSPTNSSSTQDSMEVGHSHHSMTSLSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 HHGNSSHHHHHHHHHHHHHGQQALGNRTRPRVYNSPTNSSSTQDSMEVGHSHHSMTSLSS
600 610 620 630 640 650
670 680 690 700 710 720
pF1KE3 STTSSSTSSSSTGNQGNQAYQNRPVAANTLDFGQNGAMDVNLTVYSNPRQETGIAGHPTY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 STTSSSTSSSSTGNQGNQAYQNRPVAANTLDFGQNGAMDVNLTVYSNPRQETGIAGHPTY
660 670 680 690 700 710
730 740 750 760
pF1KE3 QFSANTGPAHYMTEGHLTMRQGADREESPMTGVCVQQSPVASS
:::::::::::::::::::::::::::::::::::::::::::
CCDS13 QFSANTGPAHYMTEGHLTMRQGADREESPMTGVCVQQSPVASS
720 730 740 750
>>CCDS42926.1 DYRK1A gene_id:1859|Hs108|chr21 (584 aa)
initn: 3762 init1: 3762 opt: 3779 Z-score: 2110.0 bits: 400.8 E(32554): 3.3e-111
Smith-Waterman score: 3779; 96.7% identity (97.6% similar) in 584 aa overlap (1-576:1-584)
10 20 30 40 50 60
pF1KE3 MHTGGETSACKPSSVRLAPSFSFHAAGLQMAGQMPHSHQYSDRRQPNISDQQVSALSYSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 MHTGGETSACKPSSVRLAPSFSFHAAGLQMAGQMPHSHQYSDRRQPNISDQQVSALSYSD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 QIQQPLTNQVMPDIVMLQRRMPQTFRDPATAPLRKLSVDLIKTYKHINEVYYAKKKRRHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 QIQQPLTNQVMPDIVMLQRRMPQTFRDPATAPLRKLSVDLIKTYKHINEVYYAKKKRRHQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 QGQGDDSSHKKERKVYNDGYDDDNYDYIVKNGEKWMDRYEIDSLIGKGSFGQVVKAYDRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 QGQGDDSSHKKERKVYNDGYDDDNYDYIVKNGEKWMDRYEIDSLIGKGSFGQVVKAYDRV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 EQEWVAIKIIKNKKAFLNQAQIEVRLLELMNKHDTEMKYYIVHLKRHFMFRNHLCLVFEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 EQEWVAIKIIKNKKAFLNQAQIEVRLLELMNKHDTEMKYYIVHLKRHFMFRNHLCLVFEM
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 LSYNLYDLLRNTNFRGVSLNLTRKFAQQMCTALLFLATPELSIIHCDLKPENILLCNPKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 LSYNLYDLLRNTNFRGVSLNLTRKFAQQMCTALLFLATPELSIIHCDLKPENILLCNPKR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 SAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGMPYDLAIDMWSLGCILVEMHTGEPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 SAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGMPYDLAIDMWSLGCILVEMHTGEPL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 FSGANEVDQMNKIVEVLGIPPAHILDQAPKARKFFEKLPDGTWNLKKTKDGKREYKPPGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 FSGANEVDQMNKIVEVLGIPPAHILDQAPKARKFFEKLPDGTWNLKKTKDGKREYKPPGT
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 RKLHNILGVETGGPGGRRAGESGHTVADYLKFKDLILRMLDYDPKTRIQPYYALQHSFFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 RKLHNILGVETGGPGGRRAGESGHTVADYLKFKDLILRMLDYDPKTRIQPYYALQHSFFK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 KTADEGTNTSNSVSTSPAMEQSQSSGTTSSTSSSSGGSSGTSNSGRARSDPTHQHRHSGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 KTADEGTNTSNSVSTSPAMEQSQSSGTTSSTSSSSGGSSGTSNSGRARSDPTHQHRHSGG
490 500 510 520 530 540
550 560 570 580 590
pF1KE3 HFTAAVQAMDCETHSPQVRQQF------PAPLGWS--GTEAPTQVTVETHPVQETTFHVA
:::::::::::::::::: .. :: : :: : ..: .
CCDS42 HFTAAVQAMDCETHSPQVSSHVVHLLVSPAILRWSSTGCQVPLE
550 560 570 580
600 610 620 630 640 650
pF1KE3 PQQNALHHHHGNSSHHHHHHHHHHHHHGQQALGNRTRPRVYNSPTNSSSTQDSMEVGHSH
>>CCDS13654.1 DYRK1A gene_id:1859|Hs108|chr21 (529 aa)
initn: 3477 init1: 3477 opt: 3478 Z-score: 1944.4 bits: 370.0 E(32554): 5.5e-102
Smith-Waterman score: 3478; 98.3% identity (99.2% similar) in 528 aa overlap (1-528:1-528)
10 20 30 40 50 60
pF1KE3 MHTGGETSACKPSSVRLAPSFSFHAAGLQMAGQMPHSHQYSDRRQPNISDQQVSALSYSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 MHTGGETSACKPSSVRLAPSFSFHAAGLQMAGQMPHSHQYSDRRQPNISDQQVSALSYSD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 QIQQPLTNQVMPDIVMLQRRMPQTFRDPATAPLRKLSVDLIKTYKHINEVYYAKKKRRHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 QIQQPLTNQVMPDIVMLQRRMPQTFRDPATAPLRKLSVDLIKTYKHINEVYYAKKKRRHQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 QGQGDDSSHKKERKVYNDGYDDDNYDYIVKNGEKWMDRYEIDSLIGKGSFGQVVKAYDRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 QGQGDDSSHKKERKVYNDGYDDDNYDYIVKNGEKWMDRYEIDSLIGKGSFGQVVKAYDRV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 EQEWVAIKIIKNKKAFLNQAQIEVRLLELMNKHDTEMKYYIVHLKRHFMFRNHLCLVFEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 EQEWVAIKIIKNKKAFLNQAQIEVRLLELMNKHDTEMKYYIVHLKRHFMFRNHLCLVFEM
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 LSYNLYDLLRNTNFRGVSLNLTRKFAQQMCTALLFLATPELSIIHCDLKPENILLCNPKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 LSYNLYDLLRNTNFRGVSLNLTRKFAQQMCTALLFLATPELSIIHCDLKPENILLCNPKR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 SAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGMPYDLAIDMWSLGCILVEMHTGEPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 SAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGMPYDLAIDMWSLGCILVEMHTGEPL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 FSGANEVDQMNKIVEVLGIPPAHILDQAPKARKFFEKLPDGTWNLKKTKDGKREYKPPGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 FSGANEVDQMNKIVEVLGIPPAHILDQAPKARKFFEKLPDGTWNLKKTKDGKREYKPPGT
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 RKLHNILGVETGGPGGRRAGESGHTVADYLKFKDLILRMLDYDPKTRIQPYYALQHSFFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS13 RKLHNILGVETGGPGGRRAGESGHTVADYLKFKDLILRMLDYDPKTRIQPYYALQHSFFK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 KTADEGTNTSNSVSTSPAMEQSQSSGTTSSTSSSSGGSSGTSNSGRARSDPTHQHRHSGG
::::::::::::::::::::::::::::::::::::.:. . .: .:
CCDS13 KTADEGTNTSNSVSTSPAMEQSQSSGTTSSTSSSSGASAISCSSWLVRH
490 500 510 520
550 560 570 580 590 600
pF1KE3 HFTAAVQAMDCETHSPQVRQQFPAPLGWSGTEAPTQVTVETHPVQETTFHVAPQQNALHH
>>CCDS12543.1 DYRK1B gene_id:9149|Hs108|chr19 (629 aa)
initn: 2472 init1: 2446 opt: 2538 Z-score: 1424.6 bits: 274.1 E(32554): 4.9e-73
Smith-Waterman score: 2538; 71.3% identity (87.0% similar) in 537 aa overlap (69-598:21-549)
40 50 60 70 80 90
pF1KE3 QYSDRRQPNISDQQVSALSYSDQIQQPLTNQVMPDIVMLQRRMPQTFRDPATAPLRKLSV
::.::. .: ::.: .::: ..::::::::
CCDS12 MAVPPGHGPFSGFPGPQEHTQVLPDVRLLPRRLPLAFRDATSAPLRKLSV
10 20 30 40 50
100 110 120 130 140 150
pF1KE3 DLIKTYKHINEVYYAKKKRRHQQGQGDDSSHKKERKVYNDGYDDDNYDYIVKNGEKWMDR
:::::::::::::::::::: ::. .:::.:::.:: : ::::::.::::..::.:..:
CCDS12 DLIKTYKHINEVYYAKKKRRAQQAPPQDSSNKKEKKVLNHGYDDDNHDYIVRSGERWLER
60 70 80 90 100 110
160 170 180 190 200 210
pF1KE3 YEIDSLIGKGSFGQVVKAYDRVEQEWVAIKIIKNKKAFLNQAQIEVRLLELMNKHDTEMK
::::::::::::::::::::. :: :::::::::::::::::::.:::::::.::::::
CCDS12 YEIDSLIGKGSFGQVVKAYDHQTQELVAIKIIKNKKAFLNQAQIELRLLELMNQHDTEMK
120 130 140 150 160 170
220 230 240 250 260 270
pF1KE3 YYIVHLKRHFMFRNHLCLVFEMLSYNLYDLLRNTNFRGVSLNLTRKFAQQMCTALLFLAT
:::::::::::::::::::::.::::::::::::.:::::::::::.:::.:::::::::
CCDS12 YYIVHLKRHFMFRNHLCLVFELLSYNLYDLLRNTHFRGVSLNLTRKLAQQLCTALLFLAT
180 190 200 210 220 230
280 290 300 310 320 330
pF1KE3 PELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGMPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::
CCDS12 PELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGTPY
240 250 260 270 280 290
340 350 360 370 380 390
pF1KE3 DLAIDMWSLGCILVEMHTGEPLFSGANEVDQMNKIVEVLGIPPAHILDQAPKARKFFEKL
:::::::::::::::::::::::::.:::::::.:::::::::: .:::::::::.::.:
CCDS12 DLAIDMWSLGCILVEMHTGEPLFSGSNEVDQMNRIVEVLGIPPAAMLDQAPKARKYFERL
300 310 320 330 340 350
400 410 420 430 440 450
pF1KE3 PDGTWNLKKTKDGKREYKPPGTRKLHNILGVETGGPGGRRAGESGHTVADYLKFKDLILR
: : :.:..::. ...:. ::::.:...:::.::::::::::: ::. ::::.:.::.::
CCDS12 PGGGWTLRRTKELRKDYQGPGTRRLQEVLGVQTGGPGGRRAGEPGHSPADYLRFQDLVLR
360 370 380 390 400 410
460 470 480 490 500 510
pF1KE3 MLDYDPKTRIQPYYALQHSFFKKTADEGTNTS---NSVSTSPAMEQSQSSGTTSSTSSSS
::.:.: .::.: ::::.::..::::.:::. .:.::::: .. :..:.:. :::
CCDS12 MLEYEPAARISPLGALQHGFFRRTADEATNTGPAGSSASTSPAPLDTCPSSSTASSISSS
420 430 440 450 460 470
520 530 540 550 560 570
pF1KE3 GGSSGTSNSGRARSDPTHQHRHSGGHFTAAVQAMDCETHSPQVRQQFPA-PLGWSGTEAP
:::::.:...:. ...:. :: . ::: .:::: . : : :.: ..:
CCDS12 GGSSGSSSDNRTY---RYSNRYCGG---PGPPITDCEMNSPQVPPSQPLRP--WAGGDVP
480 490 500 510 520
580 590 600 610 620 630
pF1KE3 T---QVTVETHPVQETTFHVAPQQNALHHHHGNSSHHHHHHHHHHHHHGQQALGNRTRPR
:. . . . : .. :: :
CCDS12 HKTHQAPASASSLPGTGAQLPPQPRYLGRPPSPTSPPPPELMDVSLVGGPADCSPPHPAP
530 540 550 560 570 580
>>CCDS12544.1 DYRK1B gene_id:9149|Hs108|chr19 (601 aa)
initn: 2179 init1: 2058 opt: 2058 Z-score: 1160.0 bits: 225.0 E(32554): 2.7e-58
Smith-Waterman score: 2314; 67.4% identity (82.1% similar) in 537 aa overlap (69-598:21-521)
40 50 60 70 80 90
pF1KE3 QYSDRRQPNISDQQVSALSYSDQIQQPLTNQVMPDIVMLQRRMPQTFRDPATAPLRKLSV
::.::. .: ::.: .::: ..::::::::
CCDS12 MAVPPGHGPFSGFPGPQEHTQVLPDVRLLPRRLPLAFRDATSAPLRKLSV
10 20 30 40 50
100 110 120 130 140 150
pF1KE3 DLIKTYKHINEVYYAKKKRRHQQGQGDDSSHKKERKVYNDGYDDDNYDYIVKNGEKWMDR
:::::::::::::::::::: ::. .:::.:::.:: : ::::::.::::..::.:..:
CCDS12 DLIKTYKHINEVYYAKKKRRAQQAPPQDSSNKKEKKVLNHGYDDDNHDYIVRSGERWLER
60 70 80 90 100 110
160 170 180 190 200 210
pF1KE3 YEIDSLIGKGSFGQVVKAYDRVEQEWVAIKIIKNKKAFLNQAQIEVRLLELMNKHDTEMK
::::::::::::::::::::. :: :::::::::::::::::::.:::::::.::::::
CCDS12 YEIDSLIGKGSFGQVVKAYDHQTQELVAIKIIKNKKAFLNQAQIELRLLELMNQHDTEMK
120 130 140 150 160 170
220 230 240 250 260 270
pF1KE3 YYIVHLKRHFMFRNHLCLVFEMLSYNLYDLLRNTNFRGVSLNLTRKFAQQMCTALLFLAT
:::::::::::::::::::::.::::::::::::.:::::::::::.:::.:::::::::
CCDS12 YYIVHLKRHFMFRNHLCLVFELLSYNLYDLLRNTHFRGVSLNLTRKLAQQLCTALLFLAT
180 190 200 210 220 230
280 290 300 310 320 330
pF1KE3 PELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGMPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::
CCDS12 PELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGTPY
240 250 260 270 280 290
340 350 360 370 380 390
pF1KE3 DLAIDMWSLGCILVEMHTGEPLFSGANEVDQMNKIVEVLGIPPAHILDQAPKARKFFEKL
:::::::::::::::::::::::::.:::::::.:::::::::: .:::::::::.::.:
CCDS12 DLAIDMWSLGCILVEMHTGEPLFSGSNEVDQMNRIVEVLGIPPAAMLDQAPKARKYFERL
300 310 320 330 340 350
400 410 420 430 440 450
pF1KE3 PDGTWNLKKTKDGKREYKPPGTRKLHNILGVETGGPGGRRAGESGHTVADYLKFKDLILR
: : :.:..::. ...:. ::::.:. .::.::
CCDS12 PGGGWTLRRTKELRKDYQGPGTRRLQ----------------------------EDLVLR
360 370 380
460 470 480 490 500 510
pF1KE3 MLDYDPKTRIQPYYALQHSFFKKTADEGTNTS---NSVSTSPAMEQSQSSGTTSSTSSSS
::.:.: .::.: ::::.::..::::.:::. .:.::::: .. :..:.:. :::
CCDS12 MLEYEPAARISPLGALQHGFFRRTADEATNTGPAGSSASTSPAPLDTCPSSSTASSISSS
390 400 410 420 430 440
520 530 540 550 560 570
pF1KE3 GGSSGTSNSGRARSDPTHQHRHSGGHFTAAVQAMDCETHSPQVRQQFPA-PLGWSGTEAP
:::::.:...:. ...:. :: . ::: .:::: . : : :.: ..:
CCDS12 GGSSGSSSDNRTY---RYSNRYCGG---PGPPITDCEMNSPQVPPSQPLRP--WAGGDVP
450 460 470 480 490
580 590 600 610 620 630
pF1KE3 T---QVTVETHPVQETTFHVAPQQNALHHHHGNSSHHHHHHHHHHHHHGQQALGNRTRPR
:. . . . : .. :: :
CCDS12 HKTHQAPASASSLPGTGAQLPPQPRYLGRPPSPTSPPPPELMDVSLVGGPADCSPPHPAP
500 510 520 530 540 550
>>CCDS46075.1 DYRK1B gene_id:9149|Hs108|chr19 (589 aa)
initn: 2131 init1: 2010 opt: 2010 Z-score: 1133.6 bits: 220.1 E(32554): 8e-57
Smith-Waterman score: 2243; 66.5% identity (80.1% similar) in 537 aa overlap (69-598:21-509)
40 50 60 70 80 90
pF1KE3 QYSDRRQPNISDQQVSALSYSDQIQQPLTNQVMPDIVMLQRRMPQTFRDPATAPLRKLSV
::.::. .: ::.: .::: ..::::::::
CCDS46 MAVPPGHGPFSGFPGPQEHTQVLPDVRLLPRRLPLAFRDATSAPLRKLSV
10 20 30 40 50
100 110 120 130 140 150
pF1KE3 DLIKTYKHINEVYYAKKKRRHQQGQGDDSSHKKERKVYNDGYDDDNYDYIVKNGEKWMDR
:::::::::::::::::::: ::. .:::.:::.:: : ::::::.::::..::.:..:
CCDS46 DLIKTYKHINEVYYAKKKRRAQQAPPQDSSNKKEKKVLNHGYDDDNHDYIVRSGERWLER
60 70 80 90 100 110
160 170 180 190 200 210
pF1KE3 YEIDSLIGKGSFGQVVKAYDRVEQEWVAIKIIKNKKAFLNQAQIEVRLLELMNKHDTEMK
::::::::::::::::::::. :: :::::::::::::::::::.:::::::.::::::
CCDS46 YEIDSLIGKGSFGQVVKAYDHQTQELVAIKIIKNKKAFLNQAQIELRLLELMNQHDTEMK
120 130 140 150 160 170
220 230 240 250 260 270
pF1KE3 YYIVHLKRHFMFRNHLCLVFEMLSYNLYDLLRNTNFRGVSLNLTRKFAQQMCTALLFLAT
:::::::::::::::::::::.::::::::::::.:::::::::::.:::.:::::::::
CCDS46 YYIVHLKRHFMFRNHLCLVFELLSYNLYDLLRNTHFRGVSLNLTRKLAQQLCTALLFLAT
180 190 200 210 220 230
280 290 300 310 320 330
pF1KE3 PELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGMPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::
CCDS46 PELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGTPY
240 250 260 270 280 290
340 350 360 370 380 390
pF1KE3 DLAIDMWSLGCILVEMHTGEPLFSGANEVDQMNKIVEVLGIPPAHILDQAPKARKFFEKL
:::::::::::::::::::::::::.:::::::.:::::::::: .:::::::::.::.:
CCDS46 DLAIDMWSLGCILVEMHTGEPLFSGSNEVDQMNRIVEVLGIPPAAMLDQAPKARKYFERL
300 310 320 330 340 350
400 410 420 430 440 450
pF1KE3 PDGTWNLKKTKDGKREYKPPGTRKLHNILGVETGGPGGRRAGESGHTVADYLKFKDLILR
: : :.:..::. . :::.::
CCDS46 PGGGWTLRRTKELR----------------------------------------KDLVLR
360 370
460 470 480 490 500 510
pF1KE3 MLDYDPKTRIQPYYALQHSFFKKTADEGTNTS---NSVSTSPAMEQSQSSGTTSSTSSSS
::.:.: .::.: ::::.::..::::.:::. .:.::::: .. :..:.:. :::
CCDS46 MLEYEPAARISPLGALQHGFFRRTADEATNTGPAGSSASTSPAPLDTCPSSSTASSISSS
380 390 400 410 420 430
520 530 540 550 560 570
pF1KE3 GGSSGTSNSGRARSDPTHQHRHSGGHFTAAVQAMDCETHSPQVRQQFPA-PLGWSGTEAP
:::::.:...:. ...:. :: . ::: .:::: . : : :.: ..:
CCDS46 GGSSGSSSDNRTY---RYSNRYCGG---PGPPITDCEMNSPQVPPSQPLRP--WAGGDVP
440 450 460 470 480
580 590 600 610 620 630
pF1KE3 T---QVTVETHPVQETTFHVAPQQNALHHHHGNSSHHHHHHHHHHHHHGQQALGNRTRPR
:. . . . : .. :: :
CCDS46 HKTHQAPASASSLPGTGAQLPPQPRYLGRPPSPTSPPPPELMDVSLVGGPADCSPPHPAP
490 500 510 520 530 540
>>CCDS31000.1 DYRK3 gene_id:8444|Hs108|chr1 (568 aa)
initn: 925 init1: 470 opt: 972 Z-score: 561.0 bits: 114.1 E(32554): 6.3e-25
Smith-Waterman score: 972; 36.3% identity (66.7% similar) in 463 aa overlap (38-494:70-517)
10 20 30 40 50 60
pF1KE3 SACKPSSVRLAPSFSFHAAGLQMAGQMPHSHQYSDRRQPNISDQQVSALSYSDQIQQPLT
.....:.. .: : ...: :.. . : .
CCDS31 RRLNMTTEQFTGDHTQHFLDGGEMKVEQLFQEFGNRKSNTI---QSDGISDSEKCS-PTV
40 50 60 70 80 90
70 80 90 100 110 120
pF1KE3 NQVMPDIVMLQRRMPQTFRDPATAPLRKLSVDLIKTYKHINEVYYAKKKRRHQQGQGDDS
.: . . . .. . : ..:: .. .: ::: .: . . .
CCDS31 SQGKSSDCLNTVKSNSSSKAPKVVPLTPEQA--LKQYKHHLTAYEKLEIINYPEIYFVGP
100 110 120 130 140 150
130 140 150 160 170 180
pF1KE3 SHKKERKVY----NDGYDDDNYDYIVKNGEKWMDRYEIDSLIGKGSFGQVVKAYDRVEQE
. ::.. : : :::: . :: .. :::. ..:::::::::...::. ..
CCDS31 NAKKRHGVIGGPNNGGYDDADGAYIHVPRDHLAYRYEVLKIIGKGSFGQVARVYDHKLRQ
160 170 180 190 200 210
190 200 210 220 230 240
pF1KE3 WVAIKIIKNKKAFLNQAQIEVRLLELMNKHDTEMKYYIVHLKRHFMFRNHLCLVFEMLSY
.::.:...:.: : :: :.:.:: ..:.: .. ..:. . : ::::.:..::.::
CCDS31 YVALKMVRNEKRFHRQAAEEIRILEHLKKQDKTGSMNVIHMLESFTFRNHVCMAFELLSI
220 230 240 250 260 270
250 260 270 280 290 300
pF1KE3 NLYDLLRNTNFRGVSLNLTRKFAQQMCTALLFLATPELSIIHCDLKPENILLCNPKRSAI
.::.:.....:.: :..:.:::::.. .: : . .::::::::::::: . ::.
CCDS31 DLYELIKKNKFQGFSVQLVRKFAQSILQSL--DALHKNKIIHCDLKPENILLKHHGRSST
280 290 300 310 320 330
310 320 330 340 350 360
pF1KE3 KIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGMPYDLAIDMWSLGCILVEMHTGEPLFSG
:..:::::: :..: ::::::::.::..:: :. ::.::.::::.:. ::.::: :
CCDS31 KVIDFGSSCFEYQKLYTYIQSRFYRAPEIILGSRYSTPIDIWSFGCILAELLTGQPLFPG
340 350 360 370 380 390
370 380 390 400 410 420
pF1KE3 ANEVDQMNKIVEVLGIPPAHILDQAPKARKFFEK--LPDGTWNLKKTKDGKREYKPPGTR
.: ::. ..:.::.:: ..:.:. .:. :... .: .. ::. .:
CCDS31 EDEGDQLACMMELLGMPPPKLLEQSKRAKYFINSKGIPRYC-SVTTQADGRVVLVGGRSR
400 410 420 430 440 450
430 440 450 460 470 480
pF1KE3 KLHNILGVETGGPGGRRAGESGHTVADYLKFKDLILRMLDYDPKTRIQPYYALQHSFFKK
. : . : ::.. : . . ::: : ... : : .::..:. : ::.: ...:
CCDS31 R-----GKKRGPPGSKDWGTALKGCDDYL-FIEFLKRCLHWDPSARLTPAQALRHPWISK
460 470 480 490 500
490 500 510 520 530 540
pF1KE3 TADEGTNTSNSVSTSPAMEQSQSSGTTSSTSSSSGGSSGTSNSGRARSDPTHQHRHSGGH
.. . .: ..::
CCDS31 SVPRPLTTIDKVSGKRVVNPASAFQGLGSKLPPVVGIANKLKANLMSETNGSIPLCSVLP
510 520 530 540 550 560
>>CCDS30999.1 DYRK3 gene_id:8444|Hs108|chr1 (588 aa)
initn: 925 init1: 470 opt: 972 Z-score: 560.8 bits: 114.1 E(32554): 6.5e-25
Smith-Waterman score: 972; 36.3% identity (66.7% similar) in 463 aa overlap (38-494:90-537)
10 20 30 40 50 60
pF1KE3 SACKPSSVRLAPSFSFHAAGLQMAGQMPHSHQYSDRRQPNISDQQVSALSYSDQIQQPLT
.....:.. .: : ...: :.. . : .
CCDS30 RRLNMTTEQFTGDHTQHFLDGGEMKVEQLFQEFGNRKSNTI---QSDGISDSEKCS-PTV
60 70 80 90 100 110
70 80 90 100 110 120
pF1KE3 NQVMPDIVMLQRRMPQTFRDPATAPLRKLSVDLIKTYKHINEVYYAKKKRRHQQGQGDDS
.: . . . .. . : ..:: .. .: ::: .: . . .
CCDS30 SQGKSSDCLNTVKSNSSSKAPKVVPLTPEQA--LKQYKHHLTAYEKLEIINYPEIYFVGP
120 130 140 150 160 170
130 140 150 160 170 180
pF1KE3 SHKKERKVY----NDGYDDDNYDYIVKNGEKWMDRYEIDSLIGKGSFGQVVKAYDRVEQE
. ::.. : : :::: . :: .. :::. ..:::::::::...::. ..
CCDS30 NAKKRHGVIGGPNNGGYDDADGAYIHVPRDHLAYRYEVLKIIGKGSFGQVARVYDHKLRQ
180 190 200 210 220 230
190 200 210 220 230 240
pF1KE3 WVAIKIIKNKKAFLNQAQIEVRLLELMNKHDTEMKYYIVHLKRHFMFRNHLCLVFEMLSY
.::.:...:.: : :: :.:.:: ..:.: .. ..:. . : ::::.:..::.::
CCDS30 YVALKMVRNEKRFHRQAAEEIRILEHLKKQDKTGSMNVIHMLESFTFRNHVCMAFELLSI
240 250 260 270 280 290
250 260 270 280 290 300
pF1KE3 NLYDLLRNTNFRGVSLNLTRKFAQQMCTALLFLATPELSIIHCDLKPENILLCNPKRSAI
.::.:.....:.: :..:.:::::.. .: : . .::::::::::::: . ::.
CCDS30 DLYELIKKNKFQGFSVQLVRKFAQSILQSL--DALHKNKIIHCDLKPENILLKHHGRSST
300 310 320 330 340 350
310 320 330 340 350 360
pF1KE3 KIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGMPYDLAIDMWSLGCILVEMHTGEPLFSG
:..:::::: :..: ::::::::.::..:: :. ::.::.::::.:. ::.::: :
CCDS30 KVIDFGSSCFEYQKLYTYIQSRFYRAPEIILGSRYSTPIDIWSFGCILAELLTGQPLFPG
360 370 380 390 400 410
370 380 390 400 410 420
pF1KE3 ANEVDQMNKIVEVLGIPPAHILDQAPKARKFFEK--LPDGTWNLKKTKDGKREYKPPGTR
.: ::. ..:.::.:: ..:.:. .:. :... .: .. ::. .:
CCDS30 EDEGDQLACMMELLGMPPPKLLEQSKRAKYFINSKGIPRYC-SVTTQADGRVVLVGGRSR
420 430 440 450 460 470
430 440 450 460 470 480
pF1KE3 KLHNILGVETGGPGGRRAGESGHTVADYLKFKDLILRMLDYDPKTRIQPYYALQHSFFKK
. : . : ::.. : . . ::: : ... : : .::..:. : ::.: ...:
CCDS30 R-----GKKRGPPGSKDWGTALKGCDDYL-FIEFLKRCLHWDPSARLTPAQALRHPWISK
480 490 500 510 520
490 500 510 520 530 540
pF1KE3 TADEGTNTSNSVSTSPAMEQSQSSGTTSSTSSSSGGSSGTSNSGRARSDPTHQHRHSGGH
.. . .: ..::
CCDS30 SVPRPLTTIDKVSGKRVVNPASAFQGLGSKLPPVVGIANKLKANLMSETNGSIPLCSVLP
530 540 550 560 570 580
>>CCDS8979.1 DYRK2 gene_id:8445|Hs108|chr12 (528 aa)
initn: 892 init1: 480 opt: 963 Z-score: 556.4 bits: 113.2 E(32554): 1.1e-24
Smith-Waterman score: 969; 39.9% identity (67.1% similar) in 416 aa overlap (109-522:107-501)
80 90 100 110 120 130
pF1KE3 RRMPQTFRDPATAPLRKLSVDLIKTYKHINEVYYAKKKRRHQQGQGDDSSHKKERKVYND
:.:. . ...::. . :
CCDS89 KATPMTPEQAMKQYMQKLTAFEHHEIFSYPEIYFLGLNAKKRQGMTGGPN--------NG
80 90 100 110 120
140 150 160 170 180 190
pF1KE3 GYDDDNYDYIVKNGEKWMDRYEIDSLIGKGSFGQVVKAYDRVEQEWVAIKIIKNKKAFLN
:::::. .:. .. :::. ..::::::::::::::. .. ::.:...:.: :
CCDS89 GYDDDQGSYVQVPHDHVAYRYEVLKVIGKGSFGQVVKAYDHKVHQHVALKMVRNEKRFHR
130 140 150 160 170 180
200 210 220 230 240 250
pF1KE3 QAQIEVRLLELMNKHDTEMKYYIVHLKRHFMFRNHLCLVFEMLSYNLYDLLRNTNFRGVS
:: :.:.:: . :.: . . ..:. ..: ::::.:..::.::.:::.:.....:.: :
CCDS89 QAAEEIRILEHLRKQDKDNTMNVIHMLENFTFRNHICMTFELLSMNLYELIKKNKFQGFS
190 200 210 220 230 240
260 270 280 290 300 310
pF1KE3 LNLTRKFAQQMCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRI
: :.::::... : : . ::::::::::::: . ::.::..:::::: ::.
CCDS89 LPLVRKFAHSILQCLD--ALHKNRIIHCDLKPENILLKQQGRSGIKVIDFGSSCYEHQRV
250 260 270 280 290 300
320 330 340 350 360 370
pF1KE3 YQYIQSRFYRSPEVLLGMPYDLAIDMWSLGCILVEMHTGEPLFSGANEVDQMNKIVEVLG
: ::::::::.:::.:: : . ::::::::::.:. :: ::. : .: ::. ..:.::
CCDS89 YTYIQSRFYRAPEVILGARYGMPIDMWSLGCILAELLTGYPLLPGEDEGDQLACMIELLG
310 320 330 340 350 360
380 390 400 410 420 430
pF1KE3 IPPAHILDQAPKARKFFEKLPDGTWNLKKT-KDGKREYKPPGTRKLHNILGVETGGPGGR
.: ..:: . .:..: . . : .::. . .:. : : : .:
CCDS89 MPSQKLLDASKRAKNFVSSKGYPRYCTVTTLSDGSVVLNGGRSRR-----GKLRGPPESR
370 380 390 400 410 420
440 450 460 470 480 490
pF1KE3 RAGESGHTVADYLKFKDLILRMLDYDPKTRIQPYYALQHSFFKKTADEG-TNTSNSVSTS
. :.. . : : : :.. . :..:: .:. : ::.: .... . :. ..::.
CCDS89 EWGNALKGCDDPL-FLDFLKQCLEWDPAVRMTPGQALRHPWLRRRLPKPPTGEKTSVK--
430 440 450 460 470
500 510 520 530 540 550
pF1KE3 PAMEQSQSSGTTSSTSSSSGGSSGTSNSGRARSDPTHQHRHSGGHFTAAVQAMDCETHSP
. ..:.:. .: :. ::..:
CCDS89 ---RITESTGAITSISKLPPPSSSASKLRTNLAQMTDANGNIQQRTVLPKLVS
480 490 500 510 520
763 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 02:09:45 2016 done: Tue Nov 8 02:09:46 2016
Total Scan time: 3.240 Total Display time: 0.140
Function used was FASTA [36.3.4 Apr, 2011]