Result of FASTA (omim) for
pFN21AE3232
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3232, 540 aa
1>>>pF1KE3232 540 - 540 aa - 540 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.8842+/-0.000423; mu= 11.1666+/- 0.026
mean_var=141.4763+/-28.530, 0's: 0 Z-trim(114.5): 56 B-trim: 33 in 1/55
Lambda= 0.107828
statistics sampled from 24397 (24449) to 24397 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.634), E-opt: 0.2 (0.287), width: 16
Scan time: 9.460
The best scores are: opt bits E(85289)
NP_000899 (OMIM: 108962) atrial natriuretic peptid ( 540) 3593 571.3 2.7e-162
NP_001191304 (OMIM: 108962) atrial natriuretic pep ( 541) 3567 567.2 4.5e-161
NP_001191305 (OMIM: 108962) atrial natriuretic pep ( 324) 1884 305.2 2e-82
XP_005248366 (OMIM: 108962) PREDICTED: atrial natr ( 325) 1858 301.2 3.3e-81
XP_011512349 (OMIM: 108962) PREDICTED: atrial natr ( 318) 1846 299.3 1.2e-80
XP_011512350 (OMIM: 108962) PREDICTED: atrial natr ( 301) 1843 298.8 1.6e-80
XP_011512351 (OMIM: 108962) PREDICTED: atrial natr ( 282) 1831 296.9 5.4e-80
XP_011512352 (OMIM: 108962) PREDICTED: atrial natr ( 272) 1732 281.5 2.3e-75
XP_016864981 (OMIM: 108962) PREDICTED: atrial natr ( 500) 1721 280.0 1.2e-74
NP_003986 (OMIM: 108961,602875,615923,616255) atri (1047) 509 91.7 1.2e-17
XP_005251535 (OMIM: 108961,602875,615923,616255) P (1050) 509 91.7 1.2e-17
XP_016856863 (OMIM: 108960) PREDICTED: atrial natr ( 704) 478 86.8 2.5e-16
XP_005245275 (OMIM: 108960) PREDICTED: atrial natr (1035) 478 86.9 3.3e-16
NP_000897 (OMIM: 108960) atrial natriuretic peptid (1061) 478 86.9 3.3e-16
XP_005251536 (OMIM: 108961,602875,615923,616255) P ( 721) 230 48.2 0.0001
XP_011516192 (OMIM: 108961,602875,615923,616255) P ( 721) 230 48.2 0.0001
XP_011516194 (OMIM: 108961,602875,615923,616255) P ( 721) 230 48.2 0.0001
XP_016870234 (OMIM: 108961,602875,615923,616255) P ( 721) 230 48.2 0.0001
XP_011516195 (OMIM: 108961,602875,615923,616255) P ( 721) 230 48.2 0.0001
XP_011516193 (OMIM: 108961,602875,615923,616255) P ( 721) 230 48.2 0.0001
XP_016870236 (OMIM: 108961,602875,615923,616255) P ( 718) 229 48.0 0.00011
XP_016870235 (OMIM: 108961,602875,615923,616255) P ( 718) 229 48.0 0.00011
>>NP_000899 (OMIM: 108962) atrial natriuretic peptide re (540 aa)
initn: 3593 init1: 3593 opt: 3593 Z-score: 3034.7 bits: 571.3 E(85289): 2.7e-162
Smith-Waterman score: 3593; 100.0% identity (100.0% similar) in 540 aa overlap (1-540:1-540)
10 20 30 40 50 60
pF1KE3 MPSLLVLTFSPCVLLGWALLAGGTGGGGVGGGGGGAGIGGGRQEREALPPQKIEVLVLLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MPSLLVLTFSPCVLLGWALLAGGTGGGGVGGGGGGAGIGGGRQEREALPPQKIEVLVLLP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 QDDSYLFSLTRVRPAIEYALRSVEGNGTGRRLLPPGTRFQVAYEDSDCGNRALFSLVDRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 QDDSYLFSLTRVRPAIEYALRSVEGNGTGRRLLPPGTRFQVAYEDSDCGNRALFSLVDRV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 AAARGAKPDLILGPVCEYAAAPVARLASHWDLPMLSAGALAAGFQHKDSEYSHLTRVAPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 AAARGAKPDLILGPVCEYAAAPVARLASHWDLPMLSAGALAAGFQHKDSEYSHLTRVAPA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 YAKMGEMMLALFRHHHWSRAALVYSDDKLERNCYFTLEGVHEVFQEEGLHTSIYSFDETK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 YAKMGEMMLALFRHHHWSRAALVYSDDKLERNCYFTLEGVHEVFQEEGLHTSIYSFDETK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 DLDLEDIVRNIQASERVVIMCASSDTIRSIMLVAHRHGMTSGDYAFFNIELFNSSSYGDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 DLDLEDIVRNIQASERVVIMCASSDTIRSIMLVAHRHGMTSGDYAFFNIELFNSSSYGDG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 SWKRGDKHDFEAKQAYSSLQTVTLLRTVKPEFEKFSMEVKSSVEKQGLNMEDYVNMFVEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SWKRGDKHDFEAKQAYSSLQTVTLLRTVKPEFEKFSMEVKSSVEKQGLNMEDYVNMFVEG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 FHDAILLYVLALHEVLRAGYSKKDGGKIIQQTWNRTFEGIAGQVSIDANGDRYGDFSVIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 FHDAILLYVLALHEVLRAGYSKKDGGKIIQQTWNRTFEGIAGQVSIDANGDRYGDFSVIA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 MTDVEAGTQEVIGDYFGKEGRFEMRPNVKYPWGPLKLRIDENRIVEHTNSSPCKSCGLEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MTDVEAGTQEVIGDYFGKEGRFEMRPNVKYPWGPLKLRIDENRIVEHTNSSPCKSCGLEE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE3 SAVTGIVVGALLGAGLLMAFYFFRKKYRITIERRTQQEESNLGKHRELREDSIRSHFSVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SAVTGIVVGALLGAGLLMAFYFFRKKYRITIERRTQQEESNLGKHRELREDSIRSHFSVA
490 500 510 520 530 540
>>NP_001191304 (OMIM: 108962) atrial natriuretic peptide (541 aa)
initn: 3248 init1: 3186 opt: 3567 Z-score: 3012.8 bits: 567.2 E(85289): 4.5e-161
Smith-Waterman score: 3567; 99.6% identity (99.6% similar) in 541 aa overlap (1-540:1-541)
10 20 30 40 50 60
pF1KE3 MPSLLVLTFSPCVLLGWALLAGGTGGGGVGGGGGGAGIGGGRQEREALPPQKIEVLVLLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPSLLVLTFSPCVLLGWALLAGGTGGGGVGGGGGGAGIGGGRQEREALPPQKIEVLVLLP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 QDDSYLFSLTRVRPAIEYALRSVEGNGTGRRLLPPGTRFQVAYEDSDCGNRALFSLVDRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QDDSYLFSLTRVRPAIEYALRSVEGNGTGRRLLPPGTRFQVAYEDSDCGNRALFSLVDRV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 AAARGAKPDLILGPVCEYAAAPVARLASHWDLPMLSAGALAAGFQHKDSEYSHLTRVAPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AAARGAKPDLILGPVCEYAAAPVARLASHWDLPMLSAGALAAGFQHKDSEYSHLTRVAPA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 YAKMGEMMLALFRHHHWSRAALVYSDDKLERNCYFTLEGVHEVFQEEGLHTSIYSFDETK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YAKMGEMMLALFRHHHWSRAALVYSDDKLERNCYFTLEGVHEVFQEEGLHTSIYSFDETK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 DLDLEDIVRNIQASERVVIMCASSDTIRSIMLVAHRHGMTSGDYAFFNIELFNSSSYGDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DLDLEDIVRNIQASERVVIMCASSDTIRSIMLVAHRHGMTSGDYAFFNIELFNSSSYGDG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 SWKRGDKHDFEAKQAYSSLQTVTLLRTVKPEFEKFSMEVKSSVEKQGLNMEDYVNMFVEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SWKRGDKHDFEAKQAYSSLQTVTLLRTVKPEFEKFSMEVKSSVEKQGLNMEDYVNMFVEG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 FHDAILLYVLALHEVLRAGYSKKDGGKIIQQTWNRTFEGIAGQVSIDANGDRYGDFSVIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FHDAILLYVLALHEVLRAGYSKKDGGKIIQQTWNRTFEGIAGQVSIDANGDRYGDFSVIA
370 380 390 400 410 420
430 440 450 460 470
pF1KE3 MTDVEAGTQEVIGDYFGKEGRFEMRPNVKYPWGPLKLRIDENRIVEHTNSSPCKSCG-LE
::::::::::::::::::::::::::::::::::::::::::::::::::::::: : ::
NP_001 MTDVEAGTQEVIGDYFGKEGRFEMRPNVKYPWGPLKLRIDENRIVEHTNSSPCKSSGGLE
430 440 450 460 470 480
480 490 500 510 520 530
pF1KE3 ESAVTGIVVGALLGAGLLMAFYFFRKKYRITIERRTQQEESNLGKHRELREDSIRSHFSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESAVTGIVVGALLGAGLLMAFYFFRKKYRITIERRTQQEESNLGKHRELREDSIRSHFSV
490 500 510 520 530 540
540
pF1KE3 A
:
NP_001 A
>>NP_001191305 (OMIM: 108962) atrial natriuretic peptide (324 aa)
initn: 1882 init1: 1882 opt: 1884 Z-score: 1600.8 bits: 305.2 E(85289): 2e-82
Smith-Waterman score: 1884; 97.9% identity (99.0% similar) in 292 aa overlap (249-540:33-324)
220 230 240 250 260 270
pF1KE3 GVHEVFQEEGLHTSIYSFDETKDLDLEDIVRNIQASERVVIMCASSDTIRSIMLVAHRHG
:. .:.::::::::::::::::::::::
NP_001 PSALGPWSLFPDLAPRDQEGQVLAPRRCFRRECGQNEKVVIMCASSDTIRSIMLVAHRHG
10 20 30 40 50 60
280 290 300 310 320 330
pF1KE3 MTSGDYAFFNIELFNSSSYGDGSWKRGDKHDFEAKQAYSSLQTVTLLRTVKPEFEKFSME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MTSGDYAFFNIELFNSSSYGDGSWKRGDKHDFEAKQAYSSLQTVTLLRTVKPEFEKFSME
70 80 90 100 110 120
340 350 360 370 380 390
pF1KE3 VKSSVEKQGLNMEDYVNMFVEGFHDAILLYVLALHEVLRAGYSKKDGGKIIQQTWNRTFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VKSSVEKQGLNMEDYVNMFVEGFHDAILLYVLALHEVLRAGYSKKDGGKIIQQTWNRTFE
130 140 150 160 170 180
400 410 420 430 440 450
pF1KE3 GIAGQVSIDANGDRYGDFSVIAMTDVEAGTQEVIGDYFGKEGRFEMRPNVKYPWGPLKLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GIAGQVSIDANGDRYGDFSVIAMTDVEAGTQEVIGDYFGKEGRFEMRPNVKYPWGPLKLR
190 200 210 220 230 240
460 470 480 490 500 510
pF1KE3 IDENRIVEHTNSSPCKSCGLEESAVTGIVVGALLGAGLLMAFYFFRKKYRITIERRTQQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IDENRIVEHTNSSPCKSCGLEESAVTGIVVGALLGAGLLMAFYFFRKKYRITIERRTQQE
250 260 270 280 290 300
520 530 540
pF1KE3 ESNLGKHRELREDSIRSHFSVA
::::::::::::::::::::::
NP_001 ESNLGKHRELREDSIRSHFSVA
310 320
>>XP_005248366 (OMIM: 108962) PREDICTED: atrial natriure (325 aa)
initn: 1465 init1: 1465 opt: 1858 Z-score: 1579.0 bits: 301.2 E(85289): 3.3e-81
Smith-Waterman score: 1858; 97.3% identity (98.3% similar) in 293 aa overlap (249-540:33-325)
220 230 240 250 260 270
pF1KE3 GVHEVFQEEGLHTSIYSFDETKDLDLEDIVRNIQASERVVIMCASSDTIRSIMLVAHRHG
:. .:.::::::::::::::::::::::
XP_005 PSALGPWSLFPDLAPRDQEGQVLAPRRCFRRECGQNEKVVIMCASSDTIRSIMLVAHRHG
10 20 30 40 50 60
280 290 300 310 320 330
pF1KE3 MTSGDYAFFNIELFNSSSYGDGSWKRGDKHDFEAKQAYSSLQTVTLLRTVKPEFEKFSME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MTSGDYAFFNIELFNSSSYGDGSWKRGDKHDFEAKQAYSSLQTVTLLRTVKPEFEKFSME
70 80 90 100 110 120
340 350 360 370 380 390
pF1KE3 VKSSVEKQGLNMEDYVNMFVEGFHDAILLYVLALHEVLRAGYSKKDGGKIIQQTWNRTFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VKSSVEKQGLNMEDYVNMFVEGFHDAILLYVLALHEVLRAGYSKKDGGKIIQQTWNRTFE
130 140 150 160 170 180
400 410 420 430 440 450
pF1KE3 GIAGQVSIDANGDRYGDFSVIAMTDVEAGTQEVIGDYFGKEGRFEMRPNVKYPWGPLKLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GIAGQVSIDANGDRYGDFSVIAMTDVEAGTQEVIGDYFGKEGRFEMRPNVKYPWGPLKLR
190 200 210 220 230 240
460 470 480 490 500 510
pF1KE3 IDENRIVEHTNSSPCKSCG-LEESAVTGIVVGALLGAGLLMAFYFFRKKYRITIERRTQQ
::::::::::::::::: : ::::::::::::::::::::::::::::::::::::::::
XP_005 IDENRIVEHTNSSPCKSSGGLEESAVTGIVVGALLGAGLLMAFYFFRKKYRITIERRTQQ
250 260 270 280 290 300
520 530 540
pF1KE3 EESNLGKHRELREDSIRSHFSVA
:::::::::::::::::::::::
XP_005 EESNLGKHRELREDSIRSHFSVA
310 320
>>XP_011512349 (OMIM: 108962) PREDICTED: atrial natriure (318 aa)
initn: 1487 init1: 1465 opt: 1846 Z-score: 1569.0 bits: 299.3 E(85289): 1.2e-80
Smith-Waterman score: 1846; 99.3% identity (99.3% similar) in 285 aa overlap (257-540:34-318)
230 240 250 260 270 280
pF1KE3 EGLHTSIYSFDETKDLDLEDIVRNIQASERVVIMCASSDTIRSIMLVAHRHGMTSGDYAF
::::::::::::::::::::::::::::::
XP_011 GCAVYGTWPWGGMFQLFRPSALAGLCSIGLVVIMCASSDTIRSIMLVAHRHGMTSGDYAF
10 20 30 40 50 60
290 300 310 320 330 340
pF1KE3 FNIELFNSSSYGDGSWKRGDKHDFEAKQAYSSLQTVTLLRTVKPEFEKFSMEVKSSVEKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FNIELFNSSSYGDGSWKRGDKHDFEAKQAYSSLQTVTLLRTVKPEFEKFSMEVKSSVEKQ
70 80 90 100 110 120
350 360 370 380 390 400
pF1KE3 GLNMEDYVNMFVEGFHDAILLYVLALHEVLRAGYSKKDGGKIIQQTWNRTFEGIAGQVSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLNMEDYVNMFVEGFHDAILLYVLALHEVLRAGYSKKDGGKIIQQTWNRTFEGIAGQVSI
130 140 150 160 170 180
410 420 430 440 450 460
pF1KE3 DANGDRYGDFSVIAMTDVEAGTQEVIGDYFGKEGRFEMRPNVKYPWGPLKLRIDENRIVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DANGDRYGDFSVIAMTDVEAGTQEVIGDYFGKEGRFEMRPNVKYPWGPLKLRIDENRIVE
190 200 210 220 230 240
470 480 490 500 510 520
pF1KE3 HTNSSPCKSCG-LEESAVTGIVVGALLGAGLLMAFYFFRKKYRITIERRTQQEESNLGKH
::::::::: : ::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HTNSSPCKSSGGLEESAVTGIVVGALLGAGLLMAFYFFRKKYRITIERRTQQEESNLGKH
250 260 270 280 290 300
530 540
pF1KE3 RELREDSIRSHFSVA
:::::::::::::::
XP_011 RELREDSIRSHFSVA
310
>>XP_011512350 (OMIM: 108962) PREDICTED: atrial natriure (301 aa)
initn: 1460 init1: 1460 opt: 1843 Z-score: 1566.8 bits: 298.8 E(85289): 1.6e-80
Smith-Waterman score: 1843; 98.3% identity (99.0% similar) in 287 aa overlap (255-540:15-301)
230 240 250 260 270 280
pF1KE3 QEEGLHTSIYSFDETKDLDLEDIVRNIQASERVVIMCASSDTIRSIMLVAHRHGMTSGDY
. .:::::::::::::::::::::::::::
XP_011 MRTEMFQLTTPGILQTLVIMCASSDTIRSIMLVAHRHGMTSGDY
10 20 30 40
290 300 310 320 330 340
pF1KE3 AFFNIELFNSSSYGDGSWKRGDKHDFEAKQAYSSLQTVTLLRTVKPEFEKFSMEVKSSVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AFFNIELFNSSSYGDGSWKRGDKHDFEAKQAYSSLQTVTLLRTVKPEFEKFSMEVKSSVE
50 60 70 80 90 100
350 360 370 380 390 400
pF1KE3 KQGLNMEDYVNMFVEGFHDAILLYVLALHEVLRAGYSKKDGGKIIQQTWNRTFEGIAGQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KQGLNMEDYVNMFVEGFHDAILLYVLALHEVLRAGYSKKDGGKIIQQTWNRTFEGIAGQV
110 120 130 140 150 160
410 420 430 440 450 460
pF1KE3 SIDANGDRYGDFSVIAMTDVEAGTQEVIGDYFGKEGRFEMRPNVKYPWGPLKLRIDENRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SIDANGDRYGDFSVIAMTDVEAGTQEVIGDYFGKEGRFEMRPNVKYPWGPLKLRIDENRI
170 180 190 200 210 220
470 480 490 500 510 520
pF1KE3 VEHTNSSPCKSCG-LEESAVTGIVVGALLGAGLLMAFYFFRKKYRITIERRTQQEESNLG
::::::::::: : ::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VEHTNSSPCKSSGGLEESAVTGIVVGALLGAGLLMAFYFFRKKYRITIERRTQQEESNLG
230 240 250 260 270 280
530 540
pF1KE3 KHRELREDSIRSHFSVA
:::::::::::::::::
XP_011 KHRELREDSIRSHFSVA
290 300
>>XP_011512351 (OMIM: 108962) PREDICTED: atrial natriure (282 aa)
initn: 1450 init1: 1450 opt: 1831 Z-score: 1557.1 bits: 296.9 E(85289): 5.4e-80
Smith-Waterman score: 1831; 99.3% identity (99.3% similar) in 282 aa overlap (260-540:1-282)
230 240 250 260 270 280
pF1KE3 HTSIYSFDETKDLDLEDIVRNIQASERVVIMCASSDTIRSIMLVAHRHGMTSGDYAFFNI
::::::::::::::::::::::::::::::
XP_011 MCASSDTIRSIMLVAHRHGMTSGDYAFFNI
10 20 30
290 300 310 320 330 340
pF1KE3 ELFNSSSYGDGSWKRGDKHDFEAKQAYSSLQTVTLLRTVKPEFEKFSMEVKSSVEKQGLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELFNSSSYGDGSWKRGDKHDFEAKQAYSSLQTVTLLRTVKPEFEKFSMEVKSSVEKQGLN
40 50 60 70 80 90
350 360 370 380 390 400
pF1KE3 MEDYVNMFVEGFHDAILLYVLALHEVLRAGYSKKDGGKIIQQTWNRTFEGIAGQVSIDAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MEDYVNMFVEGFHDAILLYVLALHEVLRAGYSKKDGGKIIQQTWNRTFEGIAGQVSIDAN
100 110 120 130 140 150
410 420 430 440 450 460
pF1KE3 GDRYGDFSVIAMTDVEAGTQEVIGDYFGKEGRFEMRPNVKYPWGPLKLRIDENRIVEHTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GDRYGDFSVIAMTDVEAGTQEVIGDYFGKEGRFEMRPNVKYPWGPLKLRIDENRIVEHTN
160 170 180 190 200 210
470 480 490 500 510 520
pF1KE3 SSPCKSCG-LEESAVTGIVVGALLGAGLLMAFYFFRKKYRITIERRTQQEESNLGKHREL
:::::: : :::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSPCKSSGGLEESAVTGIVVGALLGAGLLMAFYFFRKKYRITIERRTQQEESNLGKHREL
220 230 240 250 260 270
530 540
pF1KE3 REDSIRSHFSVA
::::::::::::
XP_011 REDSIRSHFSVA
280
>>XP_011512352 (OMIM: 108962) PREDICTED: atrial natriure (272 aa)
initn: 1839 init1: 1727 opt: 1732 Z-score: 1474.1 bits: 281.5 E(85289): 2.3e-75
Smith-Waterman score: 1732; 98.5% identity (99.6% similar) in 262 aa overlap (1-261:1-262)
10 20 30 40 50 60
pF1KE3 MPSLLVLTFSPCVLLGWALLAGGTGGGGVGGGGGGAGIGGGRQEREALPPQKIEVLVLLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MPSLLVLTFSPCVLLGWALLAGGTGGGGVGGGGGGAGIGGGRQEREALPPQKIEVLVLLP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 QDDSYLFSLTRVRPAIEYALRSVEGNGTGRRLLPPGTRFQVAYEDSDCGNRALFSLVDRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QDDSYLFSLTRVRPAIEYALRSVEGNGTGRRLLPPGTRFQVAYEDSDCGNRALFSLVDRV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 AAARGAKPDLILGPVCEYAAAPVARLASHWDLPMLSAGALAAGFQHKDSEYSHLTRVAPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AAARGAKPDLILGPVCEYAAAPVARLASHWDLPMLSAGALAAGFQHKDSEYSHLTRVAPA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 YAKMGEMMLALFRHHHWSRAALVYSDDKLERNCYFTLEGVHEVFQEEGLHTSIYSFDETK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YAKMGEMMLALFRHHHWSRAALVYSDDKLERNCYFTLEGVHEVFQEEGLHTSIYSFDETK
190 200 210 220 230 240
250 260 270 280 290
pF1KE3 DLDLEDIVRNIQASERVV-IMCASSDTIRSIMLVAHRHGMTSGDYAFFNIELFNSSSYGD
:::::::::::::::::. ..:
XP_011 DLDLEDIVRNIQASERVLGLICWNPSGRKFSS
250 260 270
>>XP_016864981 (OMIM: 108962) PREDICTED: atrial natriure (500 aa)
initn: 2907 init1: 1721 opt: 1721 Z-score: 1461.3 bits: 280.0 E(85289): 1.2e-74
Smith-Waterman score: 3210; 92.1% identity (92.1% similar) in 541 aa overlap (1-540:1-500)
10 20 30 40 50 60
pF1KE3 MPSLLVLTFSPCVLLGWALLAGGTGGGGVGGGGGGAGIGGGRQEREALPPQKIEVLVLLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MPSLLVLTFSPCVLLGWALLAGGTGGGGVGGGGGGAGIGGGRQEREALPPQKIEVLVLLP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 QDDSYLFSLTRVRPAIEYALRSVEGNGTGRRLLPPGTRFQVAYEDSDCGNRALFSLVDRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QDDSYLFSLTRVRPAIEYALRSVEGNGTGRRLLPPGTRFQVAYEDSDCGNRALFSLVDRV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 AAARGAKPDLILGPVCEYAAAPVARLASHWDLPMLSAGALAAGFQHKDSEYSHLTRVAPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AAARGAKPDLILGPVCEYAAAPVARLASHWDLPMLSAGALAAGFQHKDSEYSHLTRVAPA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 YAKMGEMMLALFRHHHWSRAALVYSDDKLERNCYFTLEGVHEVFQEEGLHTSIYSFDETK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YAKMGEMMLALFRHHHWSRAALVYSDDKLERNCYFTLEGVHEVFQEEGLHTSIYSFDETK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 DLDLEDIVRNIQASERVVIMCASSDTIRSIMLVAHRHGMTSGDYAFFNIELFNSSSYGDG
:::::::::::::::: :::
XP_016 DLDLEDIVRNIQASER-----------------------------------------GDG
250
310 320 330 340 350 360
pF1KE3 SWKRGDKHDFEAKQAYSSLQTVTLLRTVKPEFEKFSMEVKSSVEKQGLNMEDYVNMFVEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SWKRGDKHDFEAKQAYSSLQTVTLLRTVKPEFEKFSMEVKSSVEKQGLNMEDYVNMFVEG
260 270 280 290 300 310
370 380 390 400 410 420
pF1KE3 FHDAILLYVLALHEVLRAGYSKKDGGKIIQQTWNRTFEGIAGQVSIDANGDRYGDFSVIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FHDAILLYVLALHEVLRAGYSKKDGGKIIQQTWNRTFEGIAGQVSIDANGDRYGDFSVIA
320 330 340 350 360 370
430 440 450 460 470
pF1KE3 MTDVEAGTQEVIGDYFGKEGRFEMRPNVKYPWGPLKLRIDENRIVEHTNSSPCKSCG-LE
::::::::::::::::::::::::::::::::::::::::::::::::::::::: : ::
XP_016 MTDVEAGTQEVIGDYFGKEGRFEMRPNVKYPWGPLKLRIDENRIVEHTNSSPCKSSGGLE
380 390 400 410 420 430
480 490 500 510 520 530
pF1KE3 ESAVTGIVVGALLGAGLLMAFYFFRKKYRITIERRTQQEESNLGKHRELREDSIRSHFSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESAVTGIVVGALLGAGLLMAFYFFRKKYRITIERRTQQEESNLGKHRELREDSIRSHFSV
440 450 460 470 480 490
540
pF1KE3 A
:
XP_016 A
500
>>NP_003986 (OMIM: 108961,602875,615923,616255) atrial n (1047 aa)
initn: 546 init1: 272 opt: 509 Z-score: 438.0 bits: 91.7 E(85289): 1.2e-17
Smith-Waterman score: 728; 30.9% identity (60.7% similar) in 512 aa overlap (36-523:11-502)
10 20 30 40 50 60
pF1KE3 VLTFSPCVLLGWALLAGGTGGGGVGGGGGGAGIGGGRQEREALPP--QKIEVLVLLPQDD
:...:: . :: ... . :.::. .
NP_003 MALPSLLLLVAALAGGVR-----PPGARNLTLAVVLPEHN
10 20 30
70 80 90 100 110 120
pF1KE3 -SYLFSLTRVRPAIEYALRSVEGNGTGRRLLPPGTRFQVAYEDSDCGNR-ALFSLVDRVA
:: .. :: ::. : ::. : : :: :: . .. :.. : .: ::
NP_003 LSYAWAWPRVGPAVALA---VEALG---RALPVDLRFVSSELEGACSEYLAPLSAVD---
40 50 60 70 80
130 140 150 160 170 180
pF1KE3 AARGAKPDLILGPVCEYAAAPVARLASHWDLPMLSAGALAAGFQHKDSEYSHLTRVAPAY
:::.::: : : :: :::.:::: ::.:.:::.:.::. :...: :.:..:.
NP_003 LKLYHDPDLLLGPGCVYPAASVARFASHWRLPLLTAGAVASGFSAKNDHYRTLVRTGPSA
90 100 110 120 130 140
190 200 210 220 230
pF1KE3 AKMGEMMLALFRHHHWS-RAALVYSDDKLE-RNCYFTLEGVHEVFQEEGLHTS--IYSFD
:.::....: : .:. ::::.: : . . : :::.::: :..: .: .. .:. .
NP_003 PKLGEFVVTLHGHFNWTARAALLYLDARTDDRPHYFTIEGVFEALQGSNLSVQHQVYARE
150 160 170 180 190 200
240 250 260 270 280 290
pF1KE3 ETKDLDLEDIVRNIQASERVVIMCASSDTIRSIMLVAHRHGMTSGDYAFFNIELFNSS--
:. .. :.:. :.: .:. . .. :.: :.:...:.:::.:: ...:. :
NP_003 PGGP---EQATHFIRANGRIVYICGPLEMLHEILLQAQRENLTNGDYVFFYLDVFGESLR
210 220 230 240 250 260
300 310 320 330 340
pF1KE3 ---SYGDGS-WK--RGDKHDFEAKQAYSSLQTVTLLRTVKPEFEKFSMEVK-SSVEKQGL
. . : :. : .. ..:.... ..: . .::...:. .. . : :.
NP_003 AGPTRATGRPWQDNRTREQAQALREAFQTVLVITYREPPNPEYQEFQNRLLIRAREDFGV
270 280 290 300 310 320
350 360 370 380 390 400
pF1KE3 NMEDYVNMFVEG-FHDAILLYVLALHEVLRAGYSKKDGGKIIQQTWNRTFEGIAGQVSID
.. . .. : :.:.::::. .:.:... : ...:: .:... .: ..:..: : .:
NP_003 ELGPSLMNLIAGCFYDGILLYAEVLNETIQEGGTREDGLRIVEKMQGRRYHGVTGLVVMD
330 340 350 360 370 380
410 420 430 440 450 460
pF1KE3 ANGDRYGDFSVIAMTDVEAGTQEVIGDYFGKEGR--FEMRPNVKYPWGPLKLRIDENRIV
:.:: :: . :: :...: . . : : : . . :: :: :. .
NP_003 KNNDRETDFVLWAMGDLDSGDFQPAAHYSGAEKQIWWTGRP---IPWVKGAPPSDNPPCA
390 400 410 420 430 440
470 480 490 500 510 520
pF1KE3 EHTNSSPCKSCGLEESAVTGIVVGALLGAGLLMAFYFFRK----KYRITIERRTQQEESN
.. : . : :.... .: . . .: .::: : .. : . :: .
NP_003 FDLDDPSCDKTPLSTLAIVALGTGITFIMFGVSSFLIFRKLMLEKELASMLWRIRWEELQ
450 460 470 480 490 500
530 540
pF1KE3 LGKHRELREDSIRSHFSVA
.:
NP_003 FGNSERYHKGAGSRLTLSLRGSSYGSLMTAHGKYQIFANTGHFKGNVVAIKHVNKKRIEL
510 520 530 540 550 560
540 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 08:59:25 2016 done: Thu Nov 3 08:59:27 2016
Total Scan time: 9.460 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]