FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE3226, 519 aa
  1>>>pF1KE3226 519 - 519 aa - 519 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.5767+/-0.000374; mu= 17.6184+/- 0.023
 mean_var=80.0397+/-16.560, 0's: 0 Z-trim(114.0): 17  B-trim: 1276 in 2/51
 Lambda= 0.143358
 statistics sampled from 23609 (23624) to 23609 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.646), E-opt: 0.2 (0.277), width:  16
 Scan time:  9.970

The best scores are:                                      opt bits E(85289)
NP_003822 (OMIM: 603579) serine/threonine-protein  ( 519) 3484 730.4  3e-210
XP_011524544 (OMIM: 603579) PREDICTED: serine/thre ( 268) 1664 353.8 3.6e-97
XP_011524545 (OMIM: 603579) PREDICTED: serine/thre ( 263) 1239 265.9   1e-70


>>NP_003822 (OMIM: 603579) serine/threonine-protein kina  (519 aa)
 initn: 3484 init1: 3484 opt: 3484  Z-score: 3895.6  bits: 730.4 E(85289): 3e-210
Smith-Waterman score: 3484; 100.0% identity (100.0% similar) in 519 aa overlap (1-519:1-519)

               10        20        30        40        50        60
pF1KE3 MDLVGVASPEPGTAAAWGPSKCPWAIPQNTISCSLADVMSEQLAKELQLEEEAAVFPEVA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MDLVGVASPEPGTAAAWGPSKCPWAIPQNTISCSLADVMSEQLAKELQLEEEAAVFPEVA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE3 VAEGPFITGENIDTSSDLMLAQMLQMEYDREYDAQLRREEKKFNGDSKVSISFENYRKVH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 VAEGPFITGENIDTSSDLMLAQMLQMEYDREYDAQLRREEKKFNGDSKVSISFENYRKVH
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE3 PYEDSDSSEDEVDWQDTRDDPYRPAKPVPTPKKGFIGKGKDITTKHDEVVCGRKNTARME
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 PYEDSDSSEDEVDWQDTRDDPYRPAKPVPTPKKGFIGKGKDITTKHDEVVCGRKNTARME
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE3 NFAPEFQVGDGIGMDLKLSNHVFNALKQHAYSEERRSARLHEKKEHSTAEKAVDPKTRLL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 NFAPEFQVGDGIGMDLKLSNHVFNALKQHAYSEERRSARLHEKKEHSTAEKAVDPKTRLL
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KE3 MYKMVNSGMLETITGCISTGKESVVFHAYGGSMEDEKEDSKVIPTECAIKVFKTTLNEFK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MYKMVNSGMLETITGCISTGKESVVFHAYGGSMEDEKEDSKVIPTECAIKVFKTTLNEFK
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KE3 NRDKYIKDDFRFKDRFSKLNPRKIIRMWAEKEMHNLARMQRAGIPCPTVVLLKKHILVMS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 NRDKYIKDDFRFKDRFSKLNPRKIIRMWAEKEMHNLARMQRAGIPCPTVVLLKKHILVMS
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KE3 FIGHDQVPAPKLKEVKLNSEEMKEAYYQTLHLMRQLYHECTLVHADLSEYNMLWHAGKVW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 FIGHDQVPAPKLKEVKLNSEEMKEAYYQTLHLMRQLYHECTLVHADLSEYNMLWHAGKVW
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KE3 LIDVSQSVEPTHPHGLEFLFRDCRNVSQFFQKGGVKEALSERELFNAVSGLNITADNEAD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LIDVSQSVEPTHPHGLEFLFRDCRNVSQFFQKGGVKEALSERELFNAVSGLNITADNEAD
              430       440       450       460       470       480

              490       500       510         
pF1KE3 FLAEIEALEKMNEDHVQKNGRKAASFLKDDGDPPLLYDE
       :::::::::::::::::::::::::::::::::::::::
NP_003 FLAEIEALEKMNEDHVQKNGRKAASFLKDDGDPPLLYDE
              490       500       510         

>>XP_011524544 (OMIM: 603579) PREDICTED: serine/threonin  (268 aa)
 initn: 1662 init1: 1662 opt: 1664  Z-score: 1865.4  bits: 353.8 E(85289): 3.6e-97
Smith-Waterman score: 1664; 96.5% identity (97.7% similar) in 259 aa overlap (261-519:15-268)

              240       250       260       270       280       290
pF1KE3 KAVDPKTRLLMYKMVNSGMLETITGCISTGKESVVFHAYGGSMEDEKEDSKVIPTECAIK
                                     :.:.. :     ::::::::::::::::::
XP_011                 MPTQKNVEVPAYMRKRSILQH-----MEDEKEDSKVIPTECAIK
                               10        20             30         

              300       310       320       330       340       350
pF1KE3 VFKTTLNEFKNRDKYIKDDFRFKDRFSKLNPRKIIRMWAEKEMHNLARMQRAGIPCPTVV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VFKTTLNEFKNRDKYIKDDFRFKDRFSKLNPRKIIRMWAEKEMHNLARMQRAGIPCPTVV
      40        50        60        70        80        90         

              360       370       380       390       400       410
pF1KE3 LLKKHILVMSFIGHDQVPAPKLKEVKLNSEEMKEAYYQTLHLMRQLYHECTLVHADLSEY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLKKHILVMSFIGHDQVPAPKLKEVKLNSEEMKEAYYQTLHLMRQLYHECTLVHADLSEY
     100       110       120       130       140       150         

              420       430       440       450       460       470
pF1KE3 NMLWHAGKVWLIDVSQSVEPTHPHGLEFLFRDCRNVSQFFQKGGVKEALSERELFNAVSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NMLWHAGKVWLIDVSQSVEPTHPHGLEFLFRDCRNVSQFFQKGGVKEALSERELFNAVSG
     160       170       180       190       200       210         

              480       490       500       510         
pF1KE3 LNITADNEADFLAEIEALEKMNEDHVQKNGRKAASFLKDDGDPPLLYDE
       :::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LNITADNEADFLAEIEALEKMNEDHVQKNGRKAASFLKDDGDPPLLYDE
     220       230       240       250       260        

>>XP_011524545 (OMIM: 603579) PREDICTED: serine/threonin  (263 aa)
 initn: 1227 init1: 1227 opt: 1239  Z-score: 1390.5  bits: 265.9 E(85289): 1e-70
Smith-Waterman score: 1239; 93.5% identity (97.5% similar) in 199 aa overlap (322-519:69-263)

             300       310       320       330        340       350
pF1KE3 FKTTLNEFKNRDKYIKDDFRFKDRFSKLNPRKIIRMWAEKEMHNL-ARMQRAGIPCPTVV
                                     :::....    ..:. .:::::::::::::
XP_011 LECWRQSLAVLVQERSLLSFMHMEGAWRMKRKIVKLY----LQNVPSRMQRAGIPCPTVV
       40        50        60        70            80        90    

              360       370       380       390       400       410
pF1KE3 LLKKHILVMSFIGHDQVPAPKLKEVKLNSEEMKEAYYQTLHLMRQLYHECTLVHADLSEY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLKKHILVMSFIGHDQVPAPKLKEVKLNSEEMKEAYYQTLHLMRQLYHECTLVHADLSEY
          100       110       120       130       140       150    

              420       430       440       450       460       470
pF1KE3 NMLWHAGKVWLIDVSQSVEPTHPHGLEFLFRDCRNVSQFFQKGGVKEALSERELFNAVSG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NMLWHAGKVWLIDVSQSVEPTHPHGLEFLFRDCRNVSQFFQKGGVKEALSERELFNAVSG
          160       170       180       190       200       210    

              480       490       500       510         
pF1KE3 LNITADNEADFLAEIEALEKMNEDHVQKNGRKAASFLKDDGDPPLLYDE
       :::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LNITADNEADFLAEIEALEKMNEDHVQKNGRKAASFLKDDGDPPLLYDE
          220       230       240       250       260   




519 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sun Nov  6 13:43:36 2016 done: Sun Nov  6 13:43:37 2016
 Total Scan time:  9.970 Total Display time: -0.030

Function used was FASTA [36.3.4 Apr, 2011]