Result of FASTA (omim) for
pFN21AE3223
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3223, 506 aa
1>>>pF1KE3223 506 - 506 aa - 506 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.2291+/-0.000413; mu= 9.0381+/- 0.026
mean_var=108.0416+/-21.840, 0's: 0 Z-trim(113.7): 32 B-trim: 695 in 1/52
Lambda= 0.123390
statistics sampled from 23145 (23174) to 23145 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.633), E-opt: 0.2 (0.272), width: 16
Scan time: 9.210
The best scores are: opt bits E(85289)
NP_788276 (OMIM: 608202) CDK5 regulatory subunit-a ( 506) 3268 592.8 7.7e-169
XP_011523599 (OMIM: 608202) PREDICTED: CDK5 regula ( 531) 3256 590.7 3.5e-168
NP_001265126 (OMIM: 608202) CDK5 regulatory subuni ( 531) 3256 590.7 3.5e-168
XP_016880655 (OMIM: 608202) PREDICTED: CDK5 regula ( 413) 2647 482.2 1.2e-135
NP_001265146 (OMIM: 608202) CDK5 regulatory subuni ( 419) 2526 460.7 3.8e-129
XP_016880654 (OMIM: 608202) PREDICTED: CDK5 regula ( 419) 2526 460.7 3.8e-129
XP_016880653 (OMIM: 608202) PREDICTED: CDK5 regula ( 419) 2526 460.7 3.8e-129
NP_001265145 (OMIM: 608202) CDK5 regulatory subuni ( 281) 1788 329.3 9.3e-90
NP_001265127 (OMIM: 608202) CDK5 regulatory subuni ( 316) 1707 314.9 2.3e-85
>>NP_788276 (OMIM: 608202) CDK5 regulatory subunit-assoc (506 aa)
initn: 3268 init1: 3268 opt: 3268 Z-score: 3152.2 bits: 592.8 E(85289): 7.7e-169
Smith-Waterman score: 3268; 100.0% identity (100.0% similar) in 506 aa overlap (1-506:1-506)
10 20 30 40 50 60
pF1KE3 MEDHQHVPIDIQTSKLLDWLVDRRHCSLKWQSLVLTIREKINAAIQDMPESEEIAQLLSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_788 MEDHQHVPIDIQTSKLLDWLVDRRHCSLKWQSLVLTIREKINAAIQDMPESEEIAQLLSG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 SYIHYFHCLRILDLLKGTEASTKNIFGRYSSQRMKDWQEIIALYEKDNTYLVELSSLLVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_788 SYIHYFHCLRILDLLKGTEASTKNIFGRYSSQRMKDWQEIIALYEKDNTYLVELSSLLVR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 NVNYEIPSLKKQIAKCQQLQQEYSRKEEECQAGAAEMREQFYHSCKQYGITGENVRGELL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_788 NVNYEIPSLKKQIAKCQQLQQEYSRKEEECQAGAAEMREQFYHSCKQYGITGENVRGELL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 ALVKDLPSQLAEIGAAAQQSLGEAIDVYQASVGFVCESPTEQVLPMLRFVQKRGNSTVYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_788 ALVKDLPSQLAEIGAAAQQSLGEAIDVYQASVGFVCESPTEQVLPMLRFVQKRGNSTVYE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 WRTGTEPSVVERPHLEELPEQVAEDAIDWGDFGVEAVSEGTDSGISAEAAGIDWGIFPES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_788 WRTGTEPSVVERPHLEELPEQVAEDAIDWGDFGVEAVSEGTDSGISAEAAGIDWGIFPES
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 DSKDPGGDGIDWGDDAVALQITVLEAGTQAPEGVARGPDALTLLEYTETRNQFLDELMEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_788 DSKDPGGDGIDWGDDAVALQITVLEAGTQAPEGVARGPDALTLLEYTETRNQFLDELMEL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 EIFLAQRAVELSEEADVLSVSQFQLAPAILQGQTKEKMVTMVSVLEDLIGKLTSLQLQHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_788 EIFLAQRAVELSEEADVLSVSQFQLAPAILQGQTKEKMVTMVSVLEDLIGKLTSLQLQHL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 FMILASPRYVDRVTEFLQQKLKQSQLLALKKELMVQKQQEALEEQAALEPKLDLLLEKTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_788 FMILASPRYVDRVTEFLQQKLKQSQLLALKKELMVQKQQEALEEQAALEPKLDLLLEKTK
430 440 450 460 470 480
490 500
pF1KE3 ELQKLIEADISKRYSGRPVNLMGTSL
::::::::::::::::::::::::::
NP_788 ELQKLIEADISKRYSGRPVNLMGTSL
490 500
>>XP_011523599 (OMIM: 608202) PREDICTED: CDK5 regulatory (531 aa)
initn: 3256 init1: 3256 opt: 3256 Z-score: 3140.3 bits: 590.7 E(85289): 3.5e-168
Smith-Waterman score: 3256; 99.8% identity (100.0% similar) in 505 aa overlap (2-506:27-531)
10 20 30
pF1KE3 MEDHQHVPIDIQTSKLLDWLVDRRHCSLKWQSLVL
.:::::::::::::::::::::::::::::::::
XP_011 MRRQSMTSATRDLHTALDGKATQGGKKDHQHVPIDIQTSKLLDWLVDRRHCSLKWQSLVL
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE3 TIREKINAAIQDMPESEEIAQLLSGSYIHYFHCLRILDLLKGTEASTKNIFGRYSSQRMK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TIREKINAAIQDMPESEEIAQLLSGSYIHYFHCLRILDLLKGTEASTKNIFGRYSSQRMK
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE3 DWQEIIALYEKDNTYLVELSSLLVRNVNYEIPSLKKQIAKCQQLQQEYSRKEEECQAGAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DWQEIIALYEKDNTYLVELSSLLVRNVNYEIPSLKKQIAKCQQLQQEYSRKEEECQAGAA
130 140 150 160 170 180
160 170 180 190 200 210
pF1KE3 EMREQFYHSCKQYGITGENVRGELLALVKDLPSQLAEIGAAAQQSLGEAIDVYQASVGFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EMREQFYHSCKQYGITGENVRGELLALVKDLPSQLAEIGAAAQQSLGEAIDVYQASVGFV
190 200 210 220 230 240
220 230 240 250 260 270
pF1KE3 CESPTEQVLPMLRFVQKRGNSTVYEWRTGTEPSVVERPHLEELPEQVAEDAIDWGDFGVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CESPTEQVLPMLRFVQKRGNSTVYEWRTGTEPSVVERPHLEELPEQVAEDAIDWGDFGVE
250 260 270 280 290 300
280 290 300 310 320 330
pF1KE3 AVSEGTDSGISAEAAGIDWGIFPESDSKDPGGDGIDWGDDAVALQITVLEAGTQAPEGVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AVSEGTDSGISAEAAGIDWGIFPESDSKDPGGDGIDWGDDAVALQITVLEAGTQAPEGVA
310 320 330 340 350 360
340 350 360 370 380 390
pF1KE3 RGPDALTLLEYTETRNQFLDELMELEIFLAQRAVELSEEADVLSVSQFQLAPAILQGQTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RGPDALTLLEYTETRNQFLDELMELEIFLAQRAVELSEEADVLSVSQFQLAPAILQGQTK
370 380 390 400 410 420
400 410 420 430 440 450
pF1KE3 EKMVTMVSVLEDLIGKLTSLQLQHLFMILASPRYVDRVTEFLQQKLKQSQLLALKKELMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKMVTMVSVLEDLIGKLTSLQLQHLFMILASPRYVDRVTEFLQQKLKQSQLLALKKELMV
430 440 450 460 470 480
460 470 480 490 500
pF1KE3 QKQQEALEEQAALEPKLDLLLEKTKELQKLIEADISKRYSGRPVNLMGTSL
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QKQQEALEEQAALEPKLDLLLEKTKELQKLIEADISKRYSGRPVNLMGTSL
490 500 510 520 530
>>NP_001265126 (OMIM: 608202) CDK5 regulatory subunit-as (531 aa)
initn: 3256 init1: 3256 opt: 3256 Z-score: 3140.3 bits: 590.7 E(85289): 3.5e-168
Smith-Waterman score: 3256; 99.8% identity (100.0% similar) in 505 aa overlap (2-506:27-531)
10 20 30
pF1KE3 MEDHQHVPIDIQTSKLLDWLVDRRHCSLKWQSLVL
.:::::::::::::::::::::::::::::::::
NP_001 MRRQSMTSATRDLHTALDGKATQGGKKDHQHVPIDIQTSKLLDWLVDRRHCSLKWQSLVL
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE3 TIREKINAAIQDMPESEEIAQLLSGSYIHYFHCLRILDLLKGTEASTKNIFGRYSSQRMK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TIREKINAAIQDMPESEEIAQLLSGSYIHYFHCLRILDLLKGTEASTKNIFGRYSSQRMK
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE3 DWQEIIALYEKDNTYLVELSSLLVRNVNYEIPSLKKQIAKCQQLQQEYSRKEEECQAGAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DWQEIIALYEKDNTYLVELSSLLVRNVNYEIPSLKKQIAKCQQLQQEYSRKEEECQAGAA
130 140 150 160 170 180
160 170 180 190 200 210
pF1KE3 EMREQFYHSCKQYGITGENVRGELLALVKDLPSQLAEIGAAAQQSLGEAIDVYQASVGFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EMREQFYHSCKQYGITGENVRGELLALVKDLPSQLAEIGAAAQQSLGEAIDVYQASVGFV
190 200 210 220 230 240
220 230 240 250 260 270
pF1KE3 CESPTEQVLPMLRFVQKRGNSTVYEWRTGTEPSVVERPHLEELPEQVAEDAIDWGDFGVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CESPTEQVLPMLRFVQKRGNSTVYEWRTGTEPSVVERPHLEELPEQVAEDAIDWGDFGVE
250 260 270 280 290 300
280 290 300 310 320 330
pF1KE3 AVSEGTDSGISAEAAGIDWGIFPESDSKDPGGDGIDWGDDAVALQITVLEAGTQAPEGVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVSEGTDSGISAEAAGIDWGIFPESDSKDPGGDGIDWGDDAVALQITVLEAGTQAPEGVA
310 320 330 340 350 360
340 350 360 370 380 390
pF1KE3 RGPDALTLLEYTETRNQFLDELMELEIFLAQRAVELSEEADVLSVSQFQLAPAILQGQTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RGPDALTLLEYTETRNQFLDELMELEIFLAQRAVELSEEADVLSVSQFQLAPAILQGQTK
370 380 390 400 410 420
400 410 420 430 440 450
pF1KE3 EKMVTMVSVLEDLIGKLTSLQLQHLFMILASPRYVDRVTEFLQQKLKQSQLLALKKELMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKMVTMVSVLEDLIGKLTSLQLQHLFMILASPRYVDRVTEFLQQKLKQSQLLALKKELMV
430 440 450 460 470 480
460 470 480 490 500
pF1KE3 QKQQEALEEQAALEPKLDLLLEKTKELQKLIEADISKRYSGRPVNLMGTSL
:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QKQQEALEEQAALEPKLDLLLEKTKELQKLIEADISKRYSGRPVNLMGTSL
490 500 510 520 530
>>XP_016880655 (OMIM: 608202) PREDICTED: CDK5 regulatory (413 aa)
initn: 2647 init1: 2647 opt: 2647 Z-score: 2556.2 bits: 482.2 E(85289): 1.2e-135
Smith-Waterman score: 2647; 100.0% identity (100.0% similar) in 413 aa overlap (94-506:1-413)
70 80 90 100 110 120
pF1KE3 HYFHCLRILDLLKGTEASTKNIFGRYSSQRMKDWQEIIALYEKDNTYLVELSSLLVRNVN
::::::::::::::::::::::::::::::
XP_016 MKDWQEIIALYEKDNTYLVELSSLLVRNVN
10 20 30
130 140 150 160 170 180
pF1KE3 YEIPSLKKQIAKCQQLQQEYSRKEEECQAGAAEMREQFYHSCKQYGITGENVRGELLALV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YEIPSLKKQIAKCQQLQQEYSRKEEECQAGAAEMREQFYHSCKQYGITGENVRGELLALV
40 50 60 70 80 90
190 200 210 220 230 240
pF1KE3 KDLPSQLAEIGAAAQQSLGEAIDVYQASVGFVCESPTEQVLPMLRFVQKRGNSTVYEWRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KDLPSQLAEIGAAAQQSLGEAIDVYQASVGFVCESPTEQVLPMLRFVQKRGNSTVYEWRT
100 110 120 130 140 150
250 260 270 280 290 300
pF1KE3 GTEPSVVERPHLEELPEQVAEDAIDWGDFGVEAVSEGTDSGISAEAAGIDWGIFPESDSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GTEPSVVERPHLEELPEQVAEDAIDWGDFGVEAVSEGTDSGISAEAAGIDWGIFPESDSK
160 170 180 190 200 210
310 320 330 340 350 360
pF1KE3 DPGGDGIDWGDDAVALQITVLEAGTQAPEGVARGPDALTLLEYTETRNQFLDELMELEIF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DPGGDGIDWGDDAVALQITVLEAGTQAPEGVARGPDALTLLEYTETRNQFLDELMELEIF
220 230 240 250 260 270
370 380 390 400 410 420
pF1KE3 LAQRAVELSEEADVLSVSQFQLAPAILQGQTKEKMVTMVSVLEDLIGKLTSLQLQHLFMI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAQRAVELSEEADVLSVSQFQLAPAILQGQTKEKMVTMVSVLEDLIGKLTSLQLQHLFMI
280 290 300 310 320 330
430 440 450 460 470 480
pF1KE3 LASPRYVDRVTEFLQQKLKQSQLLALKKELMVQKQQEALEEQAALEPKLDLLLEKTKELQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LASPRYVDRVTEFLQQKLKQSQLLALKKELMVQKQQEALEEQAALEPKLDLLLEKTKELQ
340 350 360 370 380 390
490 500
pF1KE3 KLIEADISKRYSGRPVNLMGTSL
:::::::::::::::::::::::
XP_016 KLIEADISKRYSGRPVNLMGTSL
400 410
>>NP_001265146 (OMIM: 608202) CDK5 regulatory subunit-as (419 aa)
initn: 2526 init1: 2526 opt: 2526 Z-score: 2439.6 bits: 460.7 E(85289): 3.8e-129
Smith-Waterman score: 2526; 99.5% identity (99.7% similar) in 397 aa overlap (110-506:23-419)
80 90 100 110 120 130
pF1KE3 ASTKNIFGRYSSQRMKDWQEIIALYEKDNTYLVELSSLLVRNVNYEIPSLKKQIAKCQQL
. ::::::::::::::::::::::::::::
NP_001 MCVHPGACLPHVGVSWAEFPGHFSVELSSLLVRNVNYEIPSLKKQIAKCQQL
10 20 30 40 50
140 150 160 170 180 190
pF1KE3 QQEYSRKEEECQAGAAEMREQFYHSCKQYGITGENVRGELLALVKDLPSQLAEIGAAAQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QQEYSRKEEECQAGAAEMREQFYHSCKQYGITGENVRGELLALVKDLPSQLAEIGAAAQQ
60 70 80 90 100 110
200 210 220 230 240 250
pF1KE3 SLGEAIDVYQASVGFVCESPTEQVLPMLRFVQKRGNSTVYEWRTGTEPSVVERPHLEELP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLGEAIDVYQASVGFVCESPTEQVLPMLRFVQKRGNSTVYEWRTGTEPSVVERPHLEELP
120 130 140 150 160 170
260 270 280 290 300 310
pF1KE3 EQVAEDAIDWGDFGVEAVSEGTDSGISAEAAGIDWGIFPESDSKDPGGDGIDWGDDAVAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EQVAEDAIDWGDFGVEAVSEGTDSGISAEAAGIDWGIFPESDSKDPGGDGIDWGDDAVAL
180 190 200 210 220 230
320 330 340 350 360 370
pF1KE3 QITVLEAGTQAPEGVARGPDALTLLEYTETRNQFLDELMELEIFLAQRAVELSEEADVLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QITVLEAGTQAPEGVARGPDALTLLEYTETRNQFLDELMELEIFLAQRAVELSEEADVLS
240 250 260 270 280 290
380 390 400 410 420 430
pF1KE3 VSQFQLAPAILQGQTKEKMVTMVSVLEDLIGKLTSLQLQHLFMILASPRYVDRVTEFLQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VSQFQLAPAILQGQTKEKMVTMVSVLEDLIGKLTSLQLQHLFMILASPRYVDRVTEFLQQ
300 310 320 330 340 350
440 450 460 470 480 490
pF1KE3 KLKQSQLLALKKELMVQKQQEALEEQAALEPKLDLLLEKTKELQKLIEADISKRYSGRPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KLKQSQLLALKKELMVQKQQEALEEQAALEPKLDLLLEKTKELQKLIEADISKRYSGRPV
360 370 380 390 400 410
500
pF1KE3 NLMGTSL
:::::::
NP_001 NLMGTSL
>>XP_016880654 (OMIM: 608202) PREDICTED: CDK5 regulatory (419 aa)
initn: 2526 init1: 2526 opt: 2526 Z-score: 2439.6 bits: 460.7 E(85289): 3.8e-129
Smith-Waterman score: 2526; 99.5% identity (99.7% similar) in 397 aa overlap (110-506:23-419)
80 90 100 110 120 130
pF1KE3 ASTKNIFGRYSSQRMKDWQEIIALYEKDNTYLVELSSLLVRNVNYEIPSLKKQIAKCQQL
. ::::::::::::::::::::::::::::
XP_016 MCVHPGACLPHVGVSWAEFPGHFSVELSSLLVRNVNYEIPSLKKQIAKCQQL
10 20 30 40 50
140 150 160 170 180 190
pF1KE3 QQEYSRKEEECQAGAAEMREQFYHSCKQYGITGENVRGELLALVKDLPSQLAEIGAAAQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QQEYSRKEEECQAGAAEMREQFYHSCKQYGITGENVRGELLALVKDLPSQLAEIGAAAQQ
60 70 80 90 100 110
200 210 220 230 240 250
pF1KE3 SLGEAIDVYQASVGFVCESPTEQVLPMLRFVQKRGNSTVYEWRTGTEPSVVERPHLEELP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLGEAIDVYQASVGFVCESPTEQVLPMLRFVQKRGNSTVYEWRTGTEPSVVERPHLEELP
120 130 140 150 160 170
260 270 280 290 300 310
pF1KE3 EQVAEDAIDWGDFGVEAVSEGTDSGISAEAAGIDWGIFPESDSKDPGGDGIDWGDDAVAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EQVAEDAIDWGDFGVEAVSEGTDSGISAEAAGIDWGIFPESDSKDPGGDGIDWGDDAVAL
180 190 200 210 220 230
320 330 340 350 360 370
pF1KE3 QITVLEAGTQAPEGVARGPDALTLLEYTETRNQFLDELMELEIFLAQRAVELSEEADVLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QITVLEAGTQAPEGVARGPDALTLLEYTETRNQFLDELMELEIFLAQRAVELSEEADVLS
240 250 260 270 280 290
380 390 400 410 420 430
pF1KE3 VSQFQLAPAILQGQTKEKMVTMVSVLEDLIGKLTSLQLQHLFMILASPRYVDRVTEFLQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VSQFQLAPAILQGQTKEKMVTMVSVLEDLIGKLTSLQLQHLFMILASPRYVDRVTEFLQQ
300 310 320 330 340 350
440 450 460 470 480 490
pF1KE3 KLKQSQLLALKKELMVQKQQEALEEQAALEPKLDLLLEKTKELQKLIEADISKRYSGRPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLKQSQLLALKKELMVQKQQEALEEQAALEPKLDLLLEKTKELQKLIEADISKRYSGRPV
360 370 380 390 400 410
500
pF1KE3 NLMGTSL
:::::::
XP_016 NLMGTSL
>>XP_016880653 (OMIM: 608202) PREDICTED: CDK5 regulatory (419 aa)
initn: 2526 init1: 2526 opt: 2526 Z-score: 2439.6 bits: 460.7 E(85289): 3.8e-129
Smith-Waterman score: 2526; 99.5% identity (99.7% similar) in 397 aa overlap (110-506:23-419)
80 90 100 110 120 130
pF1KE3 ASTKNIFGRYSSQRMKDWQEIIALYEKDNTYLVELSSLLVRNVNYEIPSLKKQIAKCQQL
. ::::::::::::::::::::::::::::
XP_016 MCVHPGACLPHVGVSWAEFPGHFSVELSSLLVRNVNYEIPSLKKQIAKCQQL
10 20 30 40 50
140 150 160 170 180 190
pF1KE3 QQEYSRKEEECQAGAAEMREQFYHSCKQYGITGENVRGELLALVKDLPSQLAEIGAAAQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QQEYSRKEEECQAGAAEMREQFYHSCKQYGITGENVRGELLALVKDLPSQLAEIGAAAQQ
60 70 80 90 100 110
200 210 220 230 240 250
pF1KE3 SLGEAIDVYQASVGFVCESPTEQVLPMLRFVQKRGNSTVYEWRTGTEPSVVERPHLEELP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLGEAIDVYQASVGFVCESPTEQVLPMLRFVQKRGNSTVYEWRTGTEPSVVERPHLEELP
120 130 140 150 160 170
260 270 280 290 300 310
pF1KE3 EQVAEDAIDWGDFGVEAVSEGTDSGISAEAAGIDWGIFPESDSKDPGGDGIDWGDDAVAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EQVAEDAIDWGDFGVEAVSEGTDSGISAEAAGIDWGIFPESDSKDPGGDGIDWGDDAVAL
180 190 200 210 220 230
320 330 340 350 360 370
pF1KE3 QITVLEAGTQAPEGVARGPDALTLLEYTETRNQFLDELMELEIFLAQRAVELSEEADVLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QITVLEAGTQAPEGVARGPDALTLLEYTETRNQFLDELMELEIFLAQRAVELSEEADVLS
240 250 260 270 280 290
380 390 400 410 420 430
pF1KE3 VSQFQLAPAILQGQTKEKMVTMVSVLEDLIGKLTSLQLQHLFMILASPRYVDRVTEFLQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VSQFQLAPAILQGQTKEKMVTMVSVLEDLIGKLTSLQLQHLFMILASPRYVDRVTEFLQQ
300 310 320 330 340 350
440 450 460 470 480 490
pF1KE3 KLKQSQLLALKKELMVQKQQEALEEQAALEPKLDLLLEKTKELQKLIEADISKRYSGRPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KLKQSQLLALKKELMVQKQQEALEEQAALEPKLDLLLEKTKELQKLIEADISKRYSGRPV
360 370 380 390 400 410
500
pF1KE3 NLMGTSL
:::::::
XP_016 NLMGTSL
>>NP_001265145 (OMIM: 608202) CDK5 regulatory subunit-as (281 aa)
initn: 1788 init1: 1788 opt: 1788 Z-score: 1732.4 bits: 329.3 E(85289): 9.3e-90
Smith-Waterman score: 1788; 100.0% identity (100.0% similar) in 281 aa overlap (226-506:1-281)
200 210 220 230 240 250
pF1KE3 AAQQSLGEAIDVYQASVGFVCESPTEQVLPMLRFVQKRGNSTVYEWRTGTEPSVVERPHL
::::::::::::::::::::::::::::::
NP_001 MLRFVQKRGNSTVYEWRTGTEPSVVERPHL
10 20 30
260 270 280 290 300 310
pF1KE3 EELPEQVAEDAIDWGDFGVEAVSEGTDSGISAEAAGIDWGIFPESDSKDPGGDGIDWGDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EELPEQVAEDAIDWGDFGVEAVSEGTDSGISAEAAGIDWGIFPESDSKDPGGDGIDWGDD
40 50 60 70 80 90
320 330 340 350 360 370
pF1KE3 AVALQITVLEAGTQAPEGVARGPDALTLLEYTETRNQFLDELMELEIFLAQRAVELSEEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVALQITVLEAGTQAPEGVARGPDALTLLEYTETRNQFLDELMELEIFLAQRAVELSEEA
100 110 120 130 140 150
380 390 400 410 420 430
pF1KE3 DVLSVSQFQLAPAILQGQTKEKMVTMVSVLEDLIGKLTSLQLQHLFMILASPRYVDRVTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DVLSVSQFQLAPAILQGQTKEKMVTMVSVLEDLIGKLTSLQLQHLFMILASPRYVDRVTE
160 170 180 190 200 210
440 450 460 470 480 490
pF1KE3 FLQQKLKQSQLLALKKELMVQKQQEALEEQAALEPKLDLLLEKTKELQKLIEADISKRYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FLQQKLKQSQLLALKKELMVQKQQEALEEQAALEPKLDLLLEKTKELQKLIEADISKRYS
220 230 240 250 260 270
500
pF1KE3 GRPVNLMGTSL
:::::::::::
NP_001 GRPVNLMGTSL
280
>>NP_001265127 (OMIM: 608202) CDK5 regulatory subunit-as (316 aa)
initn: 1786 init1: 1707 opt: 1707 Z-score: 1653.7 bits: 314.9 E(85289): 2.3e-85
Smith-Waterman score: 1707; 98.9% identity (99.3% similar) in 272 aa overlap (226-497:1-272)
200 210 220 230 240 250
pF1KE3 AAQQSLGEAIDVYQASVGFVCESPTEQVLPMLRFVQKRGNSTVYEWRTGTEPSVVERPHL
::::::::::::::::::::::::::::::
NP_001 MLRFVQKRGNSTVYEWRTGTEPSVVERPHL
10 20 30
260 270 280 290 300 310
pF1KE3 EELPEQVAEDAIDWGDFGVEAVSEGTDSGISAEAAGIDWGIFPESDSKDPGGDGIDWGDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EELPEQVAEDAIDWGDFGVEAVSEGTDSGISAEAAGIDWGIFPESDSKDPGGDGIDWGDD
40 50 60 70 80 90
320 330 340 350 360 370
pF1KE3 AVALQITVLEAGTQAPEGVARGPDALTLLEYTETRNQFLDELMELEIFLAQRAVELSEEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVALQITVLEAGTQAPEGVARGPDALTLLEYTETRNQFLDELMELEIFLAQRAVELSEEA
100 110 120 130 140 150
380 390 400 410 420 430
pF1KE3 DVLSVSQFQLAPAILQGQTKEKMVTMVSVLEDLIGKLTSLQLQHLFMILASPRYVDRVTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DVLSVSQFQLAPAILQGQTKEKMVTMVSVLEDLIGKLTSLQLQHLFMILASPRYVDRVTE
160 170 180 190 200 210
440 450 460 470 480 490
pF1KE3 FLQQKLKQSQLLALKKELMVQKQQEALEEQAALEPKLDLLLEKTKELQKLIEADISKRYS
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::: .
NP_001 FLQQKLKQSQLLALKKELMVQKQQEALEEQAALEPKLDLLLEKTKELQKLIEADISKRQK
220 230 240 250 260 270
500
pF1KE3 GRPVNLMGTSL
:
NP_001 TRLTGRWKATGRKRHLMVILALSMFSTRSCGDWPCGLSGENHRFSF
280 290 300 310
506 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 06:01:23 2016 done: Sun Nov 6 06:01:25 2016
Total Scan time: 9.210 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]