Result of FASTA (ccds) for
pFN21AE3222
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3222, 504 aa
1>>>pF1KE3222 504 - 504 aa - 504 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.4005+/-0.000842; mu= 17.5408+/- 0.050
mean_var=69.3197+/-13.439, 0's: 0 Z-trim(106.9): 14 B-trim: 0 in 0/49
Lambda= 0.154044
statistics sampled from 9275 (9281) to 9275 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.669), E-opt: 0.2 (0.285), width: 16
Scan time: 3.240
The best scores are: opt bits E(32554)
CCDS14477.1 TRMT2B gene_id:79979|Hs108|chrX ( 504) 3409 766.8 0
CCDS55464.1 TRMT2B gene_id:79979|Hs108|chrX ( 459) 2415 545.9 3.5e-155
CCDS13774.1 TRMT2A gene_id:27037|Hs108|chr22 ( 625) 1063 245.5 1.3e-64
CCDS58793.1 TRMT2A gene_id:27037|Hs108|chr22 ( 562) 938 217.7 2.7e-56
CCDS82693.1 TRMT2A gene_id:27037|Hs108|chr22 ( 643) 669 158.0 3e-38
>>CCDS14477.1 TRMT2B gene_id:79979|Hs108|chrX (504 aa)
initn: 3409 init1: 3409 opt: 3409 Z-score: 4092.8 bits: 766.8 E(32554): 0
Smith-Waterman score: 3409; 100.0% identity (100.0% similar) in 504 aa overlap (1-504:1-504)
10 20 30 40 50 60
pF1KE3 MAGLKRRVPLHSLRYFISMVGLFSKPGLLPWYARNPPGWSQLFLGTVCKGDFTRVIATKC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 MAGLKRRVPLHSLRYFISMVGLFSKPGLLPWYARNPPGWSQLFLGTVCKGDFTRVIATKC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 QKGQKSQKKPSHLGPLDGSWQERLADVVTPLWRLSYEEQLKVKFAAQKKILQRLESYIQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 QKGQKSQKKPSHLGPLDGSWQERLADVVTPLWRLSYEEQLKVKFAAQKKILQRLESYIQM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 LNGVSVTTAVPKSERLSCLLHPIIPSPVINGYRNKSTFSVNRGPDGNPKTVGFYLGTWRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 LNGVSVTTAVPKSERLSCLLHPIIPSPVINGYRNKSTFSVNRGPDGNPKTVGFYLGTWRD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 GNVVCVQSNHLKNIPEKHSQVAQYYEVFLRQSPLEPCLVFHEGGYWRELTVRTNSQGHTM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 GNVVCVQSNHLKNIPEKHSQVAQYYEVFLRQSPLEPCLVFHEGGYWRELTVRTNSQGHTM
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 AIITFHPQKLSQEELHVQKEIVKEFFIRGPGAACGLTSLYFQESTMTRCSHQQSPYQLLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 AIITFHPQKLSQEELHVQKEIVKEFFIRGPGAACGLTSLYFQESTMTRCSHQQSPYQLLF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 GEPYIFEELLSLKIRISPDAFFQINTAGAEMLYRTVGELTGVNSDTILLDICCGTGVIGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 GEPYIFEELLSLKIRISPDAFFQINTAGAEMLYRTVGELTGVNSDTILLDICCGTGVIGL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 SLAQHTSRVLGIELLEQAVEDARWTAAFNGITNSEFHTGQAEKILPGLLKSKEDGQSIVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 SLAQHTSRVLGIELLEQAVEDARWTAAFNGITNSEFHTGQAEKILPGLLKSKEDGQSIVA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE3 VVNPARAGLHYKVIQAIRNFRAIHTLVFVSCKLHGESTRNVIELCCPPDPAKKLLGEPFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS14 VVNPARAGLHYKVIQAIRNFRAIHTLVFVSCKLHGESTRNVIELCCPPDPAKKLLGEPFV
430 440 450 460 470 480
490 500
pF1KE3 LQQAVPVDLFPHTPHCELVLLFTR
::::::::::::::::::::::::
CCDS14 LQQAVPVDLFPHTPHCELVLLFTR
490 500
>>CCDS55464.1 TRMT2B gene_id:79979|Hs108|chrX (459 aa)
initn: 3113 init1: 2415 opt: 2415 Z-score: 2899.6 bits: 545.9 E(32554): 3.5e-155
Smith-Waterman score: 3027; 91.1% identity (91.1% similar) in 504 aa overlap (1-504:1-459)
10 20 30 40 50 60
pF1KE3 MAGLKRRVPLHSLRYFISMVGLFSKPGLLPWYARNPPGWSQLFLGTVCKGDFTRVIATKC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 MAGLKRRVPLHSLRYFISMVGLFSKPGLLPWYARNPPGWSQLFLGTVCKGDFTRVIATKC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 QKGQKSQKKPSHLGPLDGSWQERLADVVTPLWRLSYEEQLKVKFAAQKKILQRLESYIQM
:::::::::::::::::::::::::::::::::::::::::
CCDS55 QKGQKSQKKPSHLGPLDGSWQERLADVVTPLWRLSYEEQLK-------------------
70 80 90 100
130 140 150 160 170 180
pF1KE3 LNGVSVTTAVPKSERLSCLLHPIIPSPVINGYRNKSTFSVNRGPDGNPKTVGFYLGTWRD
::::::::::::::::::::::::::::::::::
CCDS55 --------------------------PVINGYRNKSTFSVNRGPDGNPKTVGFYLGTWRD
110 120 130
190 200 210 220 230 240
pF1KE3 GNVVCVQSNHLKNIPEKHSQVAQYYEVFLRQSPLEPCLVFHEGGYWRELTVRTNSQGHTM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 GNVVCVQSNHLKNIPEKHSQVAQYYEVFLRQSPLEPCLVFHEGGYWRELTVRTNSQGHTM
140 150 160 170 180 190
250 260 270 280 290 300
pF1KE3 AIITFHPQKLSQEELHVQKEIVKEFFIRGPGAACGLTSLYFQESTMTRCSHQQSPYQLLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 AIITFHPQKLSQEELHVQKEIVKEFFIRGPGAACGLTSLYFQESTMTRCSHQQSPYQLLF
200 210 220 230 240 250
310 320 330 340 350 360
pF1KE3 GEPYIFEELLSLKIRISPDAFFQINTAGAEMLYRTVGELTGVNSDTILLDICCGTGVIGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 GEPYIFEELLSLKIRISPDAFFQINTAGAEMLYRTVGELTGVNSDTILLDICCGTGVIGL
260 270 280 290 300 310
370 380 390 400 410 420
pF1KE3 SLAQHTSRVLGIELLEQAVEDARWTAAFNGITNSEFHTGQAEKILPGLLKSKEDGQSIVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 SLAQHTSRVLGIELLEQAVEDARWTAAFNGITNSEFHTGQAEKILPGLLKSKEDGQSIVA
320 330 340 350 360 370
430 440 450 460 470 480
pF1KE3 VVNPARAGLHYKVIQAIRNFRAIHTLVFVSCKLHGESTRNVIELCCPPDPAKKLLGEPFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS55 VVNPARAGLHYKVIQAIRNFRAIHTLVFVSCKLHGESTRNVIELCCPPDPAKKLLGEPFV
380 390 400 410 420 430
490 500
pF1KE3 LQQAVPVDLFPHTPHCELVLLFTR
::::::::::::::::::::::::
CCDS55 LQQAVPVDLFPHTPHCELVLLFTR
440 450
>>CCDS13774.1 TRMT2A gene_id:27037|Hs108|chr22 (625 aa)
initn: 573 init1: 371 opt: 1063 Z-score: 1273.7 bits: 245.5 E(32554): 1.3e-64
Smith-Waterman score: 1065; 37.3% identity (63.3% similar) in 520 aa overlap (1-504:77-588)
10 20 30
pF1KE3 MAGLKRRVPLHSLRYFISMVGLFSKPGLLP
. .. :.. . ..: :.. :: .:
CCDS13 AGAATGPGPQPGLYSYIRDDLFTSEIFKLELQNVPRHASFSDVRRFLGRFGL--QPHKTK
50 60 70 80 90 100
40 50 60 70 80
pF1KE3 WYARNPPGWSQLFLGTVCKGDFTRVIATKCQKGQKSQ---KKPSHLGPL------DGSWQ
... :: : ... . ::. ::. . .:. :. .: .
CCDS13 LFGQ-PPCAFVTFRSAAERDKALRVLHGALWKGRPLSVRLARPKA-DPMARRRRQEGESE
110 120 130 140 150 160
90 100 110 120 130
pF1KE3 E---RLADVVTPLWRLSYEEQLKVKFAAQKKILQRLESYIQMLNGVSVTTAVP---KSER
:.:::::::: . : :::. : ...::.: . : : . . . : ..
CCDS13 PPVTRVADVVTPLWTVPYAEQLERKQLECEQVLQKLAKEIGSTNRALLPWLLEQRHKHNK
170 180 190 200 210 220
140 150 160 170 180 190
pF1KE3 LSCLLHPIIPSPVINGYRNKSTFSVNRGPDGNPKTVGFYLGTWRDGNVVCVQSNHLKNIP
: :. . ::: . :::: : :. : ::. .::: :: .. :. . . .::
CCDS13 ACCPLEGVRPSPQQTEYRNKCEFLVGVGVDGEDNTVGCRLGKYKGGTCAVAAPFDTVHIP
230 240 250 260 270 280
200 210 220 230 240 250
pF1KE3 EKHSQVAQYYEVFLRQSPLEPCLVFHEGGYWRELTVRTNSQGHTMAIITFHPQKLSQEEL
: .::.. .. :.:..: :.:..:::::. . ..::: ::::::: :::
CCDS13 EATKQVVKAFQEFIRSTPYSAYDPETYTGHWKQLTVRTSRRHQAMAIAYFHPQKLSPEEL
290 300 310 320 330 340
260 270 280 290 300 310
pF1KE3 HVQKEIVKEFFIRGPGAACGLTSLYFQESTMTRCSHQQS-PYQLLFGEPYIFEELLSLKI
: . . : ::: : :.: ::: : . . :.. : . . :. : :.::.: .
CCDS13 AELKTSLAQHFTAGPGRASGVTCLYFVEEGQRKTPSQEGLPLEHVAGDRCIHEDLLGLTF
350 360 370 380 390 400
320 330 340 350 360 370
pF1KE3 RISPDAFFQINTAGAEMLYRTVGELTGVNSDTILLDICCGTGVIGLSLAQHTSRVLGIEL
:::: ::::.:: .::.:: .. . . ... ...::.:::::.:::.::....::.:.::
CCDS13 RISPHAFFQVNTPAAEVLYTVIQDWAQLDAGSMVLDVCCGTGTIGLALARKVKRVIGVEL
410 420 430 440 450 460
380 390 400 410 420 430
pF1KE3 LEQAVEDARWTAAFNGITNSEFHTGQAEKILPGLLKSKEDGQSIVAVVNPARAGLHYKVI
.:::::: .: : ..: ::: :.:: ..: :. :. .: .::...: ::::: :::
CCDS13 CPEAVEDARVNAQDNELSNVEFHCGRAEDLVPTLV-SRLASQHLVAILDPPRAGLHSKVI
470 480 490 500 510 520
440 450 460 470 480 490
pF1KE3 QAIRNFRAIHTLVFVSCKLHGESTRNVIELCCPPDPAKKLLGEPFVLQQAVPVDLFPHTP
::: . .. :..:::. .. . : ..:: : .... : :: .:: :::::.::
CCDS13 LAIRRAKNLRRLLYVSCNPRA-AMGNFVDLCRAP--SNRVKGIPFRPVKAVAVDLFPQTP
530 540 550 560 570
500
pF1KE3 HCELVLLFTR
:::...:: :
CCDS13 HCEMLILFERVEHPNGTGVLGPHSPPAQPTPGPPDNTLQETGTFPSS
580 590 600 610 620
>>CCDS58793.1 TRMT2A gene_id:27037|Hs108|chr22 (562 aa)
initn: 462 init1: 371 opt: 938 Z-score: 1124.3 bits: 217.7 E(32554): 2.7e-56
Smith-Waterman score: 940; 36.2% identity (61.7% similar) in 486 aa overlap (1-470:77-557)
10 20 30
pF1KE3 MAGLKRRVPLHSLRYFISMVGLFSKPGLLP
. .. :.. . ..: :.. :: .:
CCDS58 AGAATGPGPQPGLYSYIRDDLFTSEIFKLELQNVPRHASFSDVRRFLGRFGL--QPHKTK
50 60 70 80 90 100
40 50 60 70 80
pF1KE3 WYARNPPGWSQLFLGTVCKGDFTRVIATKCQKGQKSQ---KKPSHLGPL------DGSWQ
... :: : ... . ::. ::. . .:. :. .: .
CCDS58 LFGQ-PPCAFVTFRSAAERDKALRVLHGALWKGRPLSVRLARPKA-DPMARRRRQEGESE
110 120 130 140 150 160
90 100 110 120 130
pF1KE3 E---RLADVVTPLWRLSYEEQLKVKFAAQKKILQRLESYIQMLNGVSVTTAVP---KSER
:.:::::::: . : :::. : ...::.: . : : . . . : ..
CCDS58 PPVTRVADVVTPLWTVPYAEQLERKQLECEQVLQKLAKEIGSTNRALLPWLLEQRHKHNK
170 180 190 200 210 220
140 150 160 170 180 190
pF1KE3 LSCLLHPIIPSPVINGYRNKSTFSVNRGPDGNPKTVGFYLGTWRDGNVVCVQSNHLKNIP
: :. . ::: . :::: : :. : ::. .::: :: .. :. . . .::
CCDS58 ACCPLEGVRPSPQQTEYRNKCEFLVGVGVDGEDNTVGCRLGKYKGGTCAVAAPFDTVHIP
230 240 250 260 270 280
200 210 220 230 240 250
pF1KE3 EKHSQVAQYYEVFLRQSPLEPCLVFHEGGYWRELTVRTNSQGHTMAIITFHPQKLSQEEL
: .::.. .. :.:..: :.:..:::::. . ..::: ::::::: :::
CCDS58 EATKQVVKAFQEFIRSTPYSAYDPETYTGHWKQLTVRTSRRHQAMAIAYFHPQKLSPEEL
290 300 310 320 330 340
260 270 280 290 300 310
pF1KE3 HVQKEIVKEFFIRGPGAACGLTSLYFQESTMTRCSHQQS-PYQLLFGEPYIFEELLSLKI
: . . : ::: : :.: ::: : . . :.. : . . :. : :.::.: .
CCDS58 AELKTSLAQHFTAGPGRASGVTCLYFVEEGQRKTPSQEGLPLEHVAGDRCIHEDLLGLTF
350 360 370 380 390 400
320 330 340 350 360 370
pF1KE3 RISPDAFFQINTAGAEMLYRTVGELTGVNSDTILLDICCGTGVIGLSLAQHTSRVLGIEL
:::: ::::.:: .::.:: .. . . ... ...::.:::::.:::.::....::.:.::
CCDS58 RISPHAFFQVNTPAAEVLYTVIQDWAQLDAGSMVLDVCCGTGTIGLALARKVKRVIGVEL
410 420 430 440 450 460
380 390 400 410 420 430
pF1KE3 LEQAVEDARWTAAFNGITNSEFHTGQAEKILPGLLKSKEDGQSIVAVVNPARAGLHYKVI
.:::::: .: : ..: ::: :.:: ..: :. :. .: .::...: ::::: :::
CCDS58 CPEAVEDARVNAQDNELSNVEFHCGRAEDLVPTLV-SRLASQHLVAILDPPRAGLHSKVI
470 480 490 500 510 520
440 450 460 470 480 490
pF1KE3 QAIRNFRAIHTLVFVSCKLHGESTRNVIELCCPPDPAKKLLGEPFVLQQAVPVDLFPHTP
::: . .. :..:::. .. : ::.:
CCDS58 LAIRRAKNLRRLLYVSCNPRAAMGNFVDAPLFPPQPLQSPI
530 540 550 560
500
pF1KE3 HCELVLLFTR
>>CCDS82693.1 TRMT2A gene_id:27037|Hs108|chr22 (643 aa)
initn: 1001 init1: 362 opt: 669 Z-score: 800.3 bits: 158.0 E(32554): 3e-38
Smith-Waterman score: 1025; 36.2% identity (61.2% similar) in 538 aa overlap (1-504:77-606)
10 20 30
pF1KE3 MAGLKRRVPLHSLRYFISMVGLFSKPGLLP
. .. :.. . ..: :.. :: .:
CCDS82 AGAATGPGPQPGLYSYIRDDLFTSEIFKLELQNVPRHASFSDVRRFLGRFGL--QPHKTK
50 60 70 80 90 100
40 50 60 70 80
pF1KE3 WYARNPPGWSQLFLGTVCKGDFTRVIATKCQKGQKSQ---KKPSHLGPL------DGSWQ
... :: : ... . ::. ::. . .:. :. .: .
CCDS82 LFGQ-PPCAFVTFRSAAERDKALRVLHGALWKGRPLSVRLARPKA-DPMARRRRQEGESE
110 120 130 140 150 160
90 100 110 120 130
pF1KE3 E---RLADVVTPLWRLSYEEQLKVKFAAQKKILQRLESYIQMLNGVSVTTAVP---KSER
:.:::::::: . : :::. : ...::.: . : : . . . : ..
CCDS82 PPVTRVADVVTPLWTVPYAEQLERKQLECEQVLQKLAKEIGSTNRALLPWLLEQRHKHNK
170 180 190 200 210 220
140 150 160 170 180 190
pF1KE3 LSCLLHPIIPSPVINGYRNKSTFSVNRGPDGNPKTVGFYLGTWRDGNVVCVQSNHLKNIP
: :. . ::: . :::: : :. : ::. .::: :: .. :. . . .::
CCDS82 ACCPLEGVRPSPQQTEYRNKCEFLVGVGVDGEDNTVGCRLGKYKGGTCAVAAPFDTVHIP
230 240 250 260 270 280
200 210 220 230 240 250
pF1KE3 EKHSQVAQYYEVFLRQSPLEPCLVFHEGGYWRELTVRTNSQGHTMAIITFHPQKLSQEEL
: .::.. .. :.:..: :.:..:::::. . ..::: ::::::: :::
CCDS82 EATKQVVKAFQEFIRSTPYSAYDPETYTGHWKQLTVRTSRRHQAMAIAYFHPQKLSPEEL
290 300 310 320 330 340
260 270 280 290 300 310
pF1KE3 HVQKEIVKEFFIRGPGAACGLTSLYFQESTMTRCSHQQS-PYQLLFGEPYIFEELLSLKI
: . . : ::: : :.: ::: : . . :.. : . . :. : :.::.: .
CCDS82 AELKTSLAQHFTAGPGRASGVTCLYFVEEGQRKTPSQEGLPLEHVAGDRCIHEDLLGLTF
350 360 370 380 390 400
320 330 340 350 360
pF1KE3 RISPDAFFQINTAGAEMLYRTVGELTGVNSDTILLDICCGTGVIGLSLA-----------
:::: ::::.:: .::.:: .. . . ... ...::.:::::.:::.::
CCDS82 RISPHAFFQVNTPAAEVLYTVIQDWAQLDAGSMVLDVCCGTGTIGLALARGPMYSPPWVG
410 420 430 440 450 460
370 380 390 400 410
pF1KE3 -------QHTSRVLGIELLEQAVEDARWTAAFNGITNSEFHTGQAEKILPGLLKSKEDGQ
:...::.:.:: .:::::: .: : ..: ::: :.:: ..: :. :. .:
CCDS82 RHHAFLFQKVKRVIGVELCPEAVEDARVNAQDNELSNVEFHCGRAEDLVPTLV-SRLASQ
470 480 490 500 510 520
420 430 440 450 460 470
pF1KE3 SIVAVVNPARAGLHYKVIQAIRNFRAIHTLVFVSCKLHGESTRNVIELCCPPDPAKKLLG
.::...: ::::: ::: ::: . .. :..:::. .. . : ..:: : .... :
CCDS82 HLVAILDPPRAGLHSKVILAIRRAKNLRRLLYVSCNPRA-AMGNFVDLCRAP--SNRVKG
530 540 550 560 570
480 490 500
pF1KE3 EPFVLQQAVPVDLFPHTPHCELVLLFTR
:: .:: :::::.:::::...:: :
CCDS82 IPFRPVKAVAVDLFPQTPHCEMLILFERVEHPNGTGVLGPHSPPAQPTPGPPDNTLQETG
580 590 600 610 620 630
504 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 09:29:39 2016 done: Thu Nov 3 09:29:40 2016
Total Scan time: 3.240 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]