Result of FASTA (omim) for
pFN21AE3212
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3212, 479 aa
1>>>pF1KE3212 479 - 479 aa - 479 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.3666+/-0.000286; mu= 15.3487+/- 0.018
mean_var=118.8002+/-24.493, 0's: 0 Z-trim(121.3): 394 B-trim: 2377 in 2/54
Lambda= 0.117670
statistics sampled from 37315 (37720) to 37315 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.764), E-opt: 0.2 (0.442), width: 16
Scan time: 10.380
The best scores are: opt bits E(85289)
XP_005251974 (OMIM: 602778) PREDICTED: nuclear rec ( 479) 3309 572.3 1e-162
NP_201591 (OMIM: 602778) nuclear receptor subfamil ( 480) 3297 570.2 4.3e-162
NP_001480 (OMIM: 602778) nuclear receptor subfamil ( 475) 3265 564.8 1.8e-160
NP_001265475 (OMIM: 602778) nuclear receptor subfa ( 476) 3253 562.8 7.5e-160
XP_005251975 (OMIM: 602778) PREDICTED: nuclear rec ( 438) 2943 510.1 4.9e-144
NP_001263393 (OMIM: 604453) nuclear receptor subfa ( 469) 407 79.6 2.1e-14
XP_005245119 (OMIM: 604453) PREDICTED: nuclear rec ( 469) 407 79.6 2.1e-14
XP_011507684 (OMIM: 604453) PREDICTED: nuclear rec ( 469) 407 79.6 2.1e-14
NP_003813 (OMIM: 604453) nuclear receptor subfamil ( 495) 407 79.6 2.1e-14
XP_011507682 (OMIM: 604453) PREDICTED: nuclear rec ( 501) 407 79.7 2.2e-14
XP_011507683 (OMIM: 604453) PREDICTED: nuclear rec ( 501) 407 79.7 2.2e-14
XP_016856393 (OMIM: 604453) PREDICTED: nuclear rec ( 501) 407 79.7 2.2e-14
XP_011507686 (OMIM: 604453) PREDICTED: nuclear rec ( 501) 407 79.7 2.2e-14
NP_995582 (OMIM: 604453) nuclear receptor subfamil ( 541) 407 79.7 2.3e-14
NP_001036193 (OMIM: 180190) retinoic acid receptor ( 443) 403 78.9 3.1e-14
XP_011513098 (OMIM: 180246) PREDICTED: retinoic ac ( 420) 399 78.2 4.8e-14
NP_001278918 (OMIM: 180246) retinoic acid receptor ( 347) 396 77.7 6e-14
XP_016866665 (OMIM: 180246) PREDICTED: retinoic ac ( 414) 396 77.7 6.8e-14
XP_005249335 (OMIM: 180246) PREDICTED: retinoic ac ( 441) 396 77.7 7.2e-14
NP_068811 (OMIM: 180246) retinoic acid receptor RX ( 533) 396 77.8 8.2e-14
NP_001257330 (OMIM: 180246) retinoic acid receptor ( 537) 396 77.8 8.3e-14
NP_008848 (OMIM: 180247) retinoic acid receptor RX ( 463) 392 77.1 1.2e-13
NP_001277145 (OMIM: 180220,615524) retinoic acid r ( 455) 388 76.4 1.9e-13
NP_001278850 (OMIM: 180245) retinoic acid receptor ( 365) 386 76.0 2e-13
NP_001278849 (OMIM: 180245) retinoic acid receptor ( 435) 386 76.0 2.3e-13
NP_000957 (OMIM: 180190) retinoic acid receptor ga ( 454) 386 76.1 2.4e-13
NP_002948 (OMIM: 180245) retinoic acid receptor RX ( 462) 386 76.1 2.4e-13
NP_001230659 (OMIM: 180190) retinoic acid receptor ( 382) 382 75.3 3.3e-13
NP_008845 (OMIM: 601972) nuclear receptor ROR-beta ( 459) 382 75.4 3.8e-13
NP_775291 (OMIM: 600542,612237) nuclear receptor s ( 443) 381 75.2 4.2e-13
NP_001243499 (OMIM: 180247) retinoic acid receptor ( 340) 379 74.8 4.4e-13
NP_001243500 (OMIM: 180247) retinoic acid receptor ( 340) 379 74.8 4.4e-13
XP_005257609 (OMIM: 180240,612376) PREDICTED: reti ( 478) 381 75.2 4.4e-13
XP_016870651 (OMIM: 600542,612237) PREDICTED: nucl ( 626) 381 75.3 5.4e-13
NP_008912 (OMIM: 600542,612237) nuclear receptor s ( 626) 381 75.3 5.4e-13
NP_775292 (OMIM: 600542,612237) nuclear receptor s ( 637) 381 75.3 5.5e-13
XP_005257610 (OMIM: 180240,612376) PREDICTED: reti ( 462) 378 74.7 6.2e-13
XP_011523397 (OMIM: 180240,612376) PREDICTED: reti ( 462) 378 74.7 6.2e-13
NP_001138773 (OMIM: 180240,612376) retinoic acid r ( 462) 378 74.7 6.2e-13
NP_000955 (OMIM: 180240,612376) retinoic acid rece ( 462) 378 74.7 6.2e-13
XP_005257611 (OMIM: 180240,612376) PREDICTED: reti ( 462) 378 74.7 6.2e-13
XP_006711547 (OMIM: 602943,616622) PREDICTED: nucl ( 651) 380 75.2 6.3e-13
NP_004950 (OMIM: 184757,612964,612965,613957) ster ( 461) 375 74.2 8.8e-13
XP_005251928 (OMIM: 184757,612964,612965,613957) P ( 461) 375 74.2 8.8e-13
XP_011516757 (OMIM: 184757,612964,612965,613957) P ( 461) 375 74.2 8.8e-13
NP_001277229 (OMIM: 180220,615524) retinoic acid r ( 405) 374 74.0 8.9e-13
NP_001277195 (OMIM: 180220,615524) retinoic acid r ( 399) 372 73.6 1.1e-12
NP_001277206 (OMIM: 180220,615524) retinoic acid r ( 402) 372 73.6 1.1e-12
NP_000956 (OMIM: 180220,615524) retinoic acid rece ( 448) 372 73.7 1.2e-12
XP_011523398 (OMIM: 180240,612376) PREDICTED: reti ( 404) 371 73.5 1.3e-12
>>XP_005251974 (OMIM: 602778) PREDICTED: nuclear recepto (479 aa)
initn: 3309 init1: 3309 opt: 3309 Z-score: 3042.1 bits: 572.3 E(85289): 1e-162
Smith-Waterman score: 3309; 100.0% identity (100.0% similar) in 479 aa overlap (1-479:1-479)
10 20 30 40 50 60
pF1KE3 MERDEPPPSGGGGGGGSAGFLEPPAALPPPPRNGFCQDELAELDPGTISVSDDRAEQRTC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MERDEPPPSGGGGGGGSAGFLEPPAALPPPPRNGFCQDELAELDPGTISVSDDRAEQRTC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 LICGDRATGLHYGIISCEGCKGFFKRSICNKRVYRCSRDKNCVMSRKQRNRCQYCRLLKC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LICGDRATGLHYGIISCEGCKGFFKRSICNKRVYRCSRDKNCVMSRKQRNRCQYCRLLKC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 LQMGMNRKAIREDGMPGGRNKSIGPVQISEEEIERIMSGQEFEEEANHWSNHGDSDHSSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LQMGMNRKAIREDGMPGGRNKSIGPVQISEEEIERIMSGQEFEEEANHWSNHGDSDHSSP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 GNRASESNQPSPGSTLSSRSVELNGFMAFREQYMGMSVPPHYQYIPHLFSYSGHSPLLPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GNRASESNQPSPGSTLSSRSVELNGFMAFREQYMGMSVPPHYQYIPHLFSYSGHSPLLPQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 QARSLDPQSYSLIHQLLSAEDLEPLGTPMLIEDGYAVTQAELFALLCRLADELLFRQIAW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QARSLDPQSYSLIHQLLSAEDLEPLGTPMLIEDGYAVTQAELFALLCRLADELLFRQIAW
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 IKKLPFFCELSIKDYTCLLSSTWQELILLSSLTVYSKQIFGELADVTAKYSPSDEELHRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IKKLPFFCELSIKDYTCLLSSTWQELILLSSLTVYSKQIFGELADVTAKYSPSDEELHRF
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 SDEGMEVIERLIYLYHKFHQLKVSNEEYACMKAINFLNQDIRGLTSASQLEQLNKRYWYI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SDEGMEVIERLIYLYHKFHQLKVSNEEYACMKAINFLNQDIRGLTSASQLEQLNKRYWYI
370 380 390 400 410 420
430 440 450 460 470
pF1KE3 CQDFTEYKYTHQPNRFPDLMMCLPEIRYIAGKMVNVPLEQLPLLFKVVLHSCKTSVGKE
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CQDFTEYKYTHQPNRFPDLMMCLPEIRYIAGKMVNVPLEQLPLLFKVVLHSCKTSVGKE
430 440 450 460 470
>>NP_201591 (OMIM: 602778) nuclear receptor subfamily 6 (480 aa)
initn: 1901 init1: 1901 opt: 3297 Z-score: 3031.1 bits: 570.2 E(85289): 4.3e-162
Smith-Waterman score: 3297; 99.8% identity (99.8% similar) in 480 aa overlap (1-479:1-480)
10 20 30 40 50 60
pF1KE3 MERDEPPPSGGGGGGGSAGFLEPPAALPPPPRNGFCQDELAELDPGTISVSDDRAEQRTC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_201 MERDEPPPSGGGGGGGSAGFLEPPAALPPPPRNGFCQDELAELDPGTISVSDDRAEQRTC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 LICGDRATGLHYGIISCEGCKGFFKRSICNKRVYRCSRDKNCVMSRKQRNRCQYCRLLKC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_201 LICGDRATGLHYGIISCEGCKGFFKRSICNKRVYRCSRDKNCVMSRKQRNRCQYCRLLKC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 LQMGMNRKAIREDGMPGGRNKSIGPVQISEEEIERIMSGQEFEEEANHWSNHGDSDHSSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_201 LQMGMNRKAIREDGMPGGRNKSIGPVQISEEEIERIMSGQEFEEEANHWSNHGDSDHSSP
130 140 150 160 170 180
190 200 210 220 230
pF1KE3 GNRASESNQPSPGSTLSS-RSVELNGFMAFREQYMGMSVPPHYQYIPHLFSYSGHSPLLP
:::::::::::::::::: :::::::::::::::::::::::::::::::::::::::::
NP_201 GNRASESNQPSPGSTLSSSRSVELNGFMAFREQYMGMSVPPHYQYIPHLFSYSGHSPLLP
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE3 QQARSLDPQSYSLIHQLLSAEDLEPLGTPMLIEDGYAVTQAELFALLCRLADELLFRQIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_201 QQARSLDPQSYSLIHQLLSAEDLEPLGTPMLIEDGYAVTQAELFALLCRLADELLFRQIA
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE3 WIKKLPFFCELSIKDYTCLLSSTWQELILLSSLTVYSKQIFGELADVTAKYSPSDEELHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_201 WIKKLPFFCELSIKDYTCLLSSTWQELILLSSLTVYSKQIFGELADVTAKYSPSDEELHR
310 320 330 340 350 360
360 370 380 390 400 410
pF1KE3 FSDEGMEVIERLIYLYHKFHQLKVSNEEYACMKAINFLNQDIRGLTSASQLEQLNKRYWY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_201 FSDEGMEVIERLIYLYHKFHQLKVSNEEYACMKAINFLNQDIRGLTSASQLEQLNKRYWY
370 380 390 400 410 420
420 430 440 450 460 470
pF1KE3 ICQDFTEYKYTHQPNRFPDLMMCLPEIRYIAGKMVNVPLEQLPLLFKVVLHSCKTSVGKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_201 ICQDFTEYKYTHQPNRFPDLMMCLPEIRYIAGKMVNVPLEQLPLLFKVVLHSCKTSVGKE
430 440 450 460 470 480
>>NP_001480 (OMIM: 602778) nuclear receptor subfamily 6 (475 aa)
initn: 2932 init1: 2932 opt: 3265 Z-score: 3001.8 bits: 564.8 E(85289): 1.8e-160
Smith-Waterman score: 3265; 99.0% identity (99.2% similar) in 479 aa overlap (1-479:1-475)
10 20 30 40 50 60
pF1KE3 MERDEPPPSGGGGGGGSAGFLEPPAALPPPPRNGFCQDELAELDPGTISVSDDRAEQRTC
::::::::::::::::::::::::::::::::::::::::::::::: .::::::::
NP_001 MERDEPPPSGGGGGGGSAGFLEPPAALPPPPRNGFCQDELAELDPGT----NDRAEQRTC
10 20 30 40 50
70 80 90 100 110 120
pF1KE3 LICGDRATGLHYGIISCEGCKGFFKRSICNKRVYRCSRDKNCVMSRKQRNRCQYCRLLKC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LICGDRATGLHYGIISCEGCKGFFKRSICNKRVYRCSRDKNCVMSRKQRNRCQYCRLLKC
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE3 LQMGMNRKAIREDGMPGGRNKSIGPVQISEEEIERIMSGQEFEEEANHWSNHGDSDHSSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LQMGMNRKAIREDGMPGGRNKSIGPVQISEEEIERIMSGQEFEEEANHWSNHGDSDHSSP
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE3 GNRASESNQPSPGSTLSSRSVELNGFMAFREQYMGMSVPPHYQYIPHLFSYSGHSPLLPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GNRASESNQPSPGSTLSSRSVELNGFMAFREQYMGMSVPPHYQYIPHLFSYSGHSPLLPQ
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE3 QARSLDPQSYSLIHQLLSAEDLEPLGTPMLIEDGYAVTQAELFALLCRLADELLFRQIAW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QARSLDPQSYSLIHQLLSAEDLEPLGTPMLIEDGYAVTQAELFALLCRLADELLFRQIAW
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE3 IKKLPFFCELSIKDYTCLLSSTWQELILLSSLTVYSKQIFGELADVTAKYSPSDEELHRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IKKLPFFCELSIKDYTCLLSSTWQELILLSSLTVYSKQIFGELADVTAKYSPSDEELHRF
300 310 320 330 340 350
370 380 390 400 410 420
pF1KE3 SDEGMEVIERLIYLYHKFHQLKVSNEEYACMKAINFLNQDIRGLTSASQLEQLNKRYWYI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SDEGMEVIERLIYLYHKFHQLKVSNEEYACMKAINFLNQDIRGLTSASQLEQLNKRYWYI
360 370 380 390 400 410
430 440 450 460 470
pF1KE3 CQDFTEYKYTHQPNRFPDLMMCLPEIRYIAGKMVNVPLEQLPLLFKVVLHSCKTSVGKE
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CQDFTEYKYTHQPNRFPDLMMCLPEIRYIAGKMVNVPLEQLPLLFKVVLHSCKTSVGKE
420 430 440 450 460 470
>>NP_001265475 (OMIM: 602778) nuclear receptor subfamily (476 aa)
initn: 2244 init1: 1901 opt: 3253 Z-score: 2990.8 bits: 562.8 E(85289): 7.5e-160
Smith-Waterman score: 3253; 98.8% identity (99.0% similar) in 480 aa overlap (1-479:1-476)
10 20 30 40 50 60
pF1KE3 MERDEPPPSGGGGGGGSAGFLEPPAALPPPPRNGFCQDELAELDPGTISVSDDRAEQRTC
::::::::::::::::::::::::::::::::::::::::::::::: .::::::::
NP_001 MERDEPPPSGGGGGGGSAGFLEPPAALPPPPRNGFCQDELAELDPGT----NDRAEQRTC
10 20 30 40 50
70 80 90 100 110 120
pF1KE3 LICGDRATGLHYGIISCEGCKGFFKRSICNKRVYRCSRDKNCVMSRKQRNRCQYCRLLKC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LICGDRATGLHYGIISCEGCKGFFKRSICNKRVYRCSRDKNCVMSRKQRNRCQYCRLLKC
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE3 LQMGMNRKAIREDGMPGGRNKSIGPVQISEEEIERIMSGQEFEEEANHWSNHGDSDHSSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LQMGMNRKAIREDGMPGGRNKSIGPVQISEEEIERIMSGQEFEEEANHWSNHGDSDHSSP
120 130 140 150 160 170
190 200 210 220 230
pF1KE3 GNRASESNQPSPGSTLSS-RSVELNGFMAFREQYMGMSVPPHYQYIPHLFSYSGHSPLLP
:::::::::::::::::: :::::::::::::::::::::::::::::::::::::::::
NP_001 GNRASESNQPSPGSTLSSSRSVELNGFMAFREQYMGMSVPPHYQYIPHLFSYSGHSPLLP
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE3 QQARSLDPQSYSLIHQLLSAEDLEPLGTPMLIEDGYAVTQAELFALLCRLADELLFRQIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QQARSLDPQSYSLIHQLLSAEDLEPLGTPMLIEDGYAVTQAELFALLCRLADELLFRQIA
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE3 WIKKLPFFCELSIKDYTCLLSSTWQELILLSSLTVYSKQIFGELADVTAKYSPSDEELHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WIKKLPFFCELSIKDYTCLLSSTWQELILLSSLTVYSKQIFGELADVTAKYSPSDEELHR
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE3 FSDEGMEVIERLIYLYHKFHQLKVSNEEYACMKAINFLNQDIRGLTSASQLEQLNKRYWY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FSDEGMEVIERLIYLYHKFHQLKVSNEEYACMKAINFLNQDIRGLTSASQLEQLNKRYWY
360 370 380 390 400 410
420 430 440 450 460 470
pF1KE3 ICQDFTEYKYTHQPNRFPDLMMCLPEIRYIAGKMVNVPLEQLPLLFKVVLHSCKTSVGKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ICQDFTEYKYTHQPNRFPDLMMCLPEIRYIAGKMVNVPLEQLPLLFKVVLHSCKTSVGKE
420 430 440 450 460 470
>>XP_005251975 (OMIM: 602778) PREDICTED: nuclear recepto (438 aa)
initn: 1901 init1: 1901 opt: 2943 Z-score: 2706.9 bits: 510.1 E(85289): 4.9e-144
Smith-Waterman score: 2943; 99.5% identity (99.8% similar) in 433 aa overlap (48-479:6-438)
20 30 40 50 60 70
pF1KE3 AGFLEPPAALPPPPRNGFCQDELAELDPGTISVSDDRAEQRTCLICGDRATGLHYGIISC
.:::::::::::::::::::::::::::::
XP_005 METWEVSVSDDRAEQRTCLICGDRATGLHYGIISC
10 20 30
80 90 100 110 120 130
pF1KE3 EGCKGFFKRSICNKRVYRCSRDKNCVMSRKQRNRCQYCRLLKCLQMGMNRKAIREDGMPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EGCKGFFKRSICNKRVYRCSRDKNCVMSRKQRNRCQYCRLLKCLQMGMNRKAIREDGMPG
40 50 60 70 80 90
140 150 160 170 180 190
pF1KE3 GRNKSIGPVQISEEEIERIMSGQEFEEEANHWSNHGDSDHSSPGNRASESNQPSPGSTLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GRNKSIGPVQISEEEIERIMSGQEFEEEANHWSNHGDSDHSSPGNRASESNQPSPGSTLS
100 110 120 130 140 150
200 210 220 230 240 250
pF1KE3 S-RSVELNGFMAFREQYMGMSVPPHYQYIPHLFSYSGHSPLLPQQARSLDPQSYSLIHQL
: ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SSRSVELNGFMAFREQYMGMSVPPHYQYIPHLFSYSGHSPLLPQQARSLDPQSYSLIHQL
160 170 180 190 200 210
260 270 280 290 300 310
pF1KE3 LSAEDLEPLGTPMLIEDGYAVTQAELFALLCRLADELLFRQIAWIKKLPFFCELSIKDYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LSAEDLEPLGTPMLIEDGYAVTQAELFALLCRLADELLFRQIAWIKKLPFFCELSIKDYT
220 230 240 250 260 270
320 330 340 350 360 370
pF1KE3 CLLSSTWQELILLSSLTVYSKQIFGELADVTAKYSPSDEELHRFSDEGMEVIERLIYLYH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CLLSSTWQELILLSSLTVYSKQIFGELADVTAKYSPSDEELHRFSDEGMEVIERLIYLYH
280 290 300 310 320 330
380 390 400 410 420 430
pF1KE3 KFHQLKVSNEEYACMKAINFLNQDIRGLTSASQLEQLNKRYWYICQDFTEYKYTHQPNRF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KFHQLKVSNEEYACMKAINFLNQDIRGLTSASQLEQLNKRYWYICQDFTEYKYTHQPNRF
340 350 360 370 380 390
440 450 460 470
pF1KE3 PDLMMCLPEIRYIAGKMVNVPLEQLPLLFKVVLHSCKTSVGKE
:::::::::::::::::::::::::::::::::::::::::::
XP_005 PDLMMCLPEIRYIAGKMVNVPLEQLPLLFKVVLHSCKTSVGKE
400 410 420 430
>>NP_001263393 (OMIM: 604453) nuclear receptor subfamily (469 aa)
initn: 528 init1: 372 opt: 407 Z-score: 379.8 bits: 79.6 E(85289): 2.1e-14
Smith-Waterman score: 623; 27.7% identity (59.5% similar) in 447 aa overlap (48-450:2-438)
20 30 40 50 60 70
pF1KE3 AGFLEPPAALPPPPRNGFCQDELAELDPGTISVSDDRAEQRTCLICGDRATGLHYGIISC
.. : :. .. : .:::...: :::...:
NP_001 MVNYSYDEDLEELCPVCGDKVSGYHYGLLTC
10 20 30
80 90 100 110 120 130
pF1KE3 EGCKGFFKRSICNKRVYRCSRDKNCVMSRKQRNRCQYCRLLKCLQMGMNRKAIREDGMPG
:.:::::::.. :.. : : ...:: ... ::.:: :::. :::..::. .:.: : : :
NP_001 ESCKGFFKRTVQNNKRYTCIENQNCQIDKTQRKRCPYCRFQKCLSVGMKLEAVRADRMRG
40 50 60 70 80 90
140 150 160 170 180 190
pF1KE3 GRNKSIGPVQISEEEIER----IMSGQEFEEEANHWSNHGDSDHSSPGNRASESNQPSPG
:::: .::. .. ... .. .. .. :: .. . . .. .. .. : :
NP_001 GRNK-FGPMYKRDRALKQQKKALIRANGLKLEAMSQVIQAMPSDLTISSAIQNIHSASKG
100 110 120 130 140 150
200 210 220 230
pF1KE3 STLSSRSVELNGF--MAFREQYMGMSVPPH-----YQYIPHLFSYS--------------
:. .. . . : . ..:..::: :: :. : .
NP_001 LPLNHAALPPTDYDRSPFVTSPISMTMPPHGSLQGYQTYGHFPSRAIKSEYPDPYTSSPE
160 170 180 190 200 210
240 250 260 270 280
pF1KE3 ---GHSPLLPQQARSLDPQSYS-LIHQLLSAEDLEPLGTPMLI-----EDGYAVTQAEL-
:.: . :. : : : :: .::. : :: .. :.. . .:
NP_001 SIMGYSYMDSYQTSS--PASIPHLILELLKCEPDEPQVQAKIMAYLQQEQANRSKHEKLS
220 230 240 250 260
290 300 310 320 330
pF1KE3 -FALLCRLADELLFRQIAWIKKLPFFCELSIKDYTCLLSSTWQELILLSSL---TVYSKQ
:.:.:..::. :: . : .. :: ::.. : ::.. :.::..:. . .:..:.
NP_001 TFGLMCKMADQTLFSIVEWARSSIFFRELKVDDQMKLLQNCWSELLILDHIYRQVVHGKE
270 280 290 300 310 320
340 350 360 370 380 390
pF1KE3 --IF---GELADVTAKYSPSDEELHRFSDEGMEVIERLIYLYHKFHQLKVSNEEYACMKA
:: :. .: . : . :. . ....:.. .: ..:. ...:..:.:
NP_001 GSIFLVTGQQVDYSIIASQAGATLNNLMSHAQELVAKL-------RSLQFDQREFVCLKF
330 340 350 360 370 380
400 410 420 430 440 450
pF1KE3 INFLNQDIRGLTSASQLEQLNKRYWYICQDFTEYKYTHQPNRFPDLMMCLPEIRYIAGKM
. ... :...: . . .: .... :.: .: .: ..: .:.. ::::: :.
NP_001 LVLFSLDVKNLENFQLVEGVQEQVNAALLDYTMCNYPQQTEKFGQLLLRLPEIRAISMQA
390 400 410 420 430 440
460 470
pF1KE3 VNVPLEQLPLLFKVVLHSCKTSVGKE
NP_001 EEYLYYKHLNGDVPYNNLLIEMLHAKRA
450 460
>>XP_005245119 (OMIM: 604453) PREDICTED: nuclear recepto (469 aa)
initn: 528 init1: 372 opt: 407 Z-score: 379.8 bits: 79.6 E(85289): 2.1e-14
Smith-Waterman score: 623; 27.7% identity (59.5% similar) in 447 aa overlap (48-450:2-438)
20 30 40 50 60 70
pF1KE3 AGFLEPPAALPPPPRNGFCQDELAELDPGTISVSDDRAEQRTCLICGDRATGLHYGIISC
.. : :. .. : .:::...: :::...:
XP_005 MVNYSYDEDLEELCPVCGDKVSGYHYGLLTC
10 20 30
80 90 100 110 120 130
pF1KE3 EGCKGFFKRSICNKRVYRCSRDKNCVMSRKQRNRCQYCRLLKCLQMGMNRKAIREDGMPG
:.:::::::.. :.. : : ...:: ... ::.:: :::. :::..::. .:.: : : :
XP_005 ESCKGFFKRTVQNNKRYTCIENQNCQIDKTQRKRCPYCRFQKCLSVGMKLEAVRADRMRG
40 50 60 70 80 90
140 150 160 170 180 190
pF1KE3 GRNKSIGPVQISEEEIER----IMSGQEFEEEANHWSNHGDSDHSSPGNRASESNQPSPG
:::: .::. .. ... .. .. .. :: .. . . .. .. .. : :
XP_005 GRNK-FGPMYKRDRALKQQKKALIRANGLKLEAMSQVIQAMPSDLTISSAIQNIHSASKG
100 110 120 130 140 150
200 210 220 230
pF1KE3 STLSSRSVELNGF--MAFREQYMGMSVPPH-----YQYIPHLFSYS--------------
:. .. . . : . ..:..::: :: :. : .
XP_005 LPLNHAALPPTDYDRSPFVTSPISMTMPPHGSLQGYQTYGHFPSRAIKSEYPDPYTSSPE
160 170 180 190 200 210
240 250 260 270 280
pF1KE3 ---GHSPLLPQQARSLDPQSYS-LIHQLLSAEDLEPLGTPMLI-----EDGYAVTQAEL-
:.: . :. : : : :: .::. : :: .. :.. . .:
XP_005 SIMGYSYMDSYQTSS--PASIPHLILELLKCEPDEPQVQAKIMAYLQQEQANRSKHEKLS
220 230 240 250 260
290 300 310 320 330
pF1KE3 -FALLCRLADELLFRQIAWIKKLPFFCELSIKDYTCLLSSTWQELILLSSL---TVYSKQ
:.:.:..::. :: . : .. :: ::.. : ::.. :.::..:. . .:..:.
XP_005 TFGLMCKMADQTLFSIVEWARSSIFFRELKVDDQMKLLQNCWSELLILDHIYRQVVHGKE
270 280 290 300 310 320
340 350 360 370 380 390
pF1KE3 --IF---GELADVTAKYSPSDEELHRFSDEGMEVIERLIYLYHKFHQLKVSNEEYACMKA
:: :. .: . : . :. . ....:.. .: ..:. ...:..:.:
XP_005 GSIFLVTGQQVDYSIIASQAGATLNNLMSHAQELVAKL-------RSLQFDQREFVCLKF
330 340 350 360 370 380
400 410 420 430 440 450
pF1KE3 INFLNQDIRGLTSASQLEQLNKRYWYICQDFTEYKYTHQPNRFPDLMMCLPEIRYIAGKM
. ... :...: . . .: .... :.: .: .: ..: .:.. ::::: :.
XP_005 LVLFSLDVKNLENFQLVEGVQEQVNAALLDYTMCNYPQQTEKFGQLLLRLPEIRAISMQA
390 400 410 420 430 440
460 470
pF1KE3 VNVPLEQLPLLFKVVLHSCKTSVGKE
XP_005 EEYLYYKHLNGDVPYNNLLIEMLHAKRA
450 460
>>XP_011507684 (OMIM: 604453) PREDICTED: nuclear recepto (469 aa)
initn: 528 init1: 372 opt: 407 Z-score: 379.8 bits: 79.6 E(85289): 2.1e-14
Smith-Waterman score: 623; 27.7% identity (59.5% similar) in 447 aa overlap (48-450:2-438)
20 30 40 50 60 70
pF1KE3 AGFLEPPAALPPPPRNGFCQDELAELDPGTISVSDDRAEQRTCLICGDRATGLHYGIISC
.. : :. .. : .:::...: :::...:
XP_011 MVNYSYDEDLEELCPVCGDKVSGYHYGLLTC
10 20 30
80 90 100 110 120 130
pF1KE3 EGCKGFFKRSICNKRVYRCSRDKNCVMSRKQRNRCQYCRLLKCLQMGMNRKAIREDGMPG
:.:::::::.. :.. : : ...:: ... ::.:: :::. :::..::. .:.: : : :
XP_011 ESCKGFFKRTVQNNKRYTCIENQNCQIDKTQRKRCPYCRFQKCLSVGMKLEAVRADRMRG
40 50 60 70 80 90
140 150 160 170 180 190
pF1KE3 GRNKSIGPVQISEEEIER----IMSGQEFEEEANHWSNHGDSDHSSPGNRASESNQPSPG
:::: .::. .. ... .. .. .. :: .. . . .. .. .. : :
XP_011 GRNK-FGPMYKRDRALKQQKKALIRANGLKLEAMSQVIQAMPSDLTISSAIQNIHSASKG
100 110 120 130 140 150
200 210 220 230
pF1KE3 STLSSRSVELNGF--MAFREQYMGMSVPPH-----YQYIPHLFSYS--------------
:. .. . . : . ..:..::: :: :. : .
XP_011 LPLNHAALPPTDYDRSPFVTSPISMTMPPHGSLQGYQTYGHFPSRAIKSEYPDPYTSSPE
160 170 180 190 200 210
240 250 260 270 280
pF1KE3 ---GHSPLLPQQARSLDPQSYS-LIHQLLSAEDLEPLGTPMLI-----EDGYAVTQAEL-
:.: . :. : : : :: .::. : :: .. :.. . .:
XP_011 SIMGYSYMDSYQTSS--PASIPHLILELLKCEPDEPQVQAKIMAYLQQEQANRSKHEKLS
220 230 240 250 260
290 300 310 320 330
pF1KE3 -FALLCRLADELLFRQIAWIKKLPFFCELSIKDYTCLLSSTWQELILLSSL---TVYSKQ
:.:.:..::. :: . : .. :: ::.. : ::.. :.::..:. . .:..:.
XP_011 TFGLMCKMADQTLFSIVEWARSSIFFRELKVDDQMKLLQNCWSELLILDHIYRQVVHGKE
270 280 290 300 310 320
340 350 360 370 380 390
pF1KE3 --IF---GELADVTAKYSPSDEELHRFSDEGMEVIERLIYLYHKFHQLKVSNEEYACMKA
:: :. .: . : . :. . ....:.. .: ..:. ...:..:.:
XP_011 GSIFLVTGQQVDYSIIASQAGATLNNLMSHAQELVAKL-------RSLQFDQREFVCLKF
330 340 350 360 370 380
400 410 420 430 440 450
pF1KE3 INFLNQDIRGLTSASQLEQLNKRYWYICQDFTEYKYTHQPNRFPDLMMCLPEIRYIAGKM
. ... :...: . . .: .... :.: .: .: ..: .:.. ::::: :.
XP_011 LVLFSLDVKNLENFQLVEGVQEQVNAALLDYTMCNYPQQTEKFGQLLLRLPEIRAISMQA
390 400 410 420 430 440
460 470
pF1KE3 VNVPLEQLPLLFKVVLHSCKTSVGKE
XP_011 EEYLYYKHLNGDVPYNNLLIEMLHAKRA
450 460
>>NP_003813 (OMIM: 604453) nuclear receptor subfamily 5 (495 aa)
initn: 528 init1: 372 opt: 407 Z-score: 379.4 bits: 79.6 E(85289): 2.1e-14
Smith-Waterman score: 623; 27.7% identity (59.5% similar) in 447 aa overlap (48-450:28-464)
20 30 40 50 60 70
pF1KE3 AGFLEPPAALPPPPRNGFCQDELAELDPGTISVSDDRAEQRTCLICGDRATGLHYGIISC
.. : :. .. : .:::...: :::...:
NP_003 MSSNSDTGDLQESLKHGLTPIVSQFKMVNYSYDEDLEELCPVCGDKVSGYHYGLLTC
10 20 30 40 50
80 90 100 110 120 130
pF1KE3 EGCKGFFKRSICNKRVYRCSRDKNCVMSRKQRNRCQYCRLLKCLQMGMNRKAIREDGMPG
:.:::::::.. :.. : : ...:: ... ::.:: :::. :::..::. .:.: : : :
NP_003 ESCKGFFKRTVQNNKRYTCIENQNCQIDKTQRKRCPYCRFQKCLSVGMKLEAVRADRMRG
60 70 80 90 100 110
140 150 160 170 180 190
pF1KE3 GRNKSIGPVQISEEEIER----IMSGQEFEEEANHWSNHGDSDHSSPGNRASESNQPSPG
:::: .::. .. ... .. .. .. :: .. . . .. .. .. : :
NP_003 GRNK-FGPMYKRDRALKQQKKALIRANGLKLEAMSQVIQAMPSDLTISSAIQNIHSASKG
120 130 140 150 160 170
200 210 220 230
pF1KE3 STLSSRSVELNGF--MAFREQYMGMSVPPH-----YQYIPHLFSYS--------------
:. .. . . : . ..:..::: :: :. : .
NP_003 LPLNHAALPPTDYDRSPFVTSPISMTMPPHGSLQGYQTYGHFPSRAIKSEYPDPYTSSPE
180 190 200 210 220 230
240 250 260 270 280
pF1KE3 ---GHSPLLPQQARSLDPQSYS-LIHQLLSAEDLEPLGTPMLI-----EDGYAVTQAEL-
:.: . :. : : : :: .::. : :: .. :.. . .:
NP_003 SIMGYSYMDSYQTSS--PASIPHLILELLKCEPDEPQVQAKIMAYLQQEQANRSKHEKLS
240 250 260 270 280 290
290 300 310 320 330
pF1KE3 -FALLCRLADELLFRQIAWIKKLPFFCELSIKDYTCLLSSTWQELILLSSL---TVYSKQ
:.:.:..::. :: . : .. :: ::.. : ::.. :.::..:. . .:..:.
NP_003 TFGLMCKMADQTLFSIVEWARSSIFFRELKVDDQMKLLQNCWSELLILDHIYRQVVHGKE
300 310 320 330 340 350
340 350 360 370 380 390
pF1KE3 --IF---GELADVTAKYSPSDEELHRFSDEGMEVIERLIYLYHKFHQLKVSNEEYACMKA
:: :. .: . : . :. . ....:.. .: ..:. ...:..:.:
NP_003 GSIFLVTGQQVDYSIIASQAGATLNNLMSHAQELVAKL-------RSLQFDQREFVCLKF
360 370 380 390 400
400 410 420 430 440 450
pF1KE3 INFLNQDIRGLTSASQLEQLNKRYWYICQDFTEYKYTHQPNRFPDLMMCLPEIRYIAGKM
. ... :...: . . .: .... :.: .: .: ..: .:.. ::::: :.
NP_003 LVLFSLDVKNLENFQLVEGVQEQVNAALLDYTMCNYPQQTEKFGQLLLRLPEIRAISMQA
410 420 430 440 450 460
460 470
pF1KE3 VNVPLEQLPLLFKVVLHSCKTSVGKE
NP_003 EEYLYYKHLNGDVPYNNLLIEMLHAKRA
470 480 490
>>XP_011507682 (OMIM: 604453) PREDICTED: nuclear recepto (501 aa)
initn: 528 init1: 372 opt: 407 Z-score: 379.4 bits: 79.7 E(85289): 2.2e-14
Smith-Waterman score: 623; 27.7% identity (59.5% similar) in 447 aa overlap (48-450:34-470)
20 30 40 50 60 70
pF1KE3 AGFLEPPAALPPPPRNGFCQDELAELDPGTISVSDDRAEQRTCLICGDRATGLHYGIISC
.. : :. .. : .:::...: :::...:
XP_011 KVETEALGLARSHGEQGQMPENMQVSQFKMVNYSYDEDLEELCPVCGDKVSGYHYGLLTC
10 20 30 40 50 60
80 90 100 110 120 130
pF1KE3 EGCKGFFKRSICNKRVYRCSRDKNCVMSRKQRNRCQYCRLLKCLQMGMNRKAIREDGMPG
:.:::::::.. :.. : : ...:: ... ::.:: :::. :::..::. .:.: : : :
XP_011 ESCKGFFKRTVQNNKRYTCIENQNCQIDKTQRKRCPYCRFQKCLSVGMKLEAVRADRMRG
70 80 90 100 110 120
140 150 160 170 180 190
pF1KE3 GRNKSIGPVQISEEEIER----IMSGQEFEEEANHWSNHGDSDHSSPGNRASESNQPSPG
:::: .::. .. ... .. .. .. :: .. . . .. .. .. : :
XP_011 GRNK-FGPMYKRDRALKQQKKALIRANGLKLEAMSQVIQAMPSDLTISSAIQNIHSASKG
130 140 150 160 170 180
200 210 220 230
pF1KE3 STLSSRSVELNGF--MAFREQYMGMSVPPH-----YQYIPHLFSYS--------------
:. .. . . : . ..:..::: :: :. : .
XP_011 LPLNHAALPPTDYDRSPFVTSPISMTMPPHGSLQGYQTYGHFPSRAIKSEYPDPYTSSPE
190 200 210 220 230 240
240 250 260 270 280
pF1KE3 ---GHSPLLPQQARSLDPQSYS-LIHQLLSAEDLEPLGTPMLI-----EDGYAVTQAEL-
:.: . :. : : : :: .::. : :: .. :.. . .:
XP_011 SIMGYSYMDSYQTSS--PASIPHLILELLKCEPDEPQVQAKIMAYLQQEQANRSKHEKLS
250 260 270 280 290 300
290 300 310 320 330
pF1KE3 -FALLCRLADELLFRQIAWIKKLPFFCELSIKDYTCLLSSTWQELILLSSL---TVYSKQ
:.:.:..::. :: . : .. :: ::.. : ::.. :.::..:. . .:..:.
XP_011 TFGLMCKMADQTLFSIVEWARSSIFFRELKVDDQMKLLQNCWSELLILDHIYRQVVHGKE
310 320 330 340 350 360
340 350 360 370 380 390
pF1KE3 --IF---GELADVTAKYSPSDEELHRFSDEGMEVIERLIYLYHKFHQLKVSNEEYACMKA
:: :. .: . : . :. . ....:.. .: ..:. ...:..:.:
XP_011 GSIFLVTGQQVDYSIIASQAGATLNNLMSHAQELVAKL-------RSLQFDQREFVCLKF
370 380 390 400 410
400 410 420 430 440 450
pF1KE3 INFLNQDIRGLTSASQLEQLNKRYWYICQDFTEYKYTHQPNRFPDLMMCLPEIRYIAGKM
. ... :...: . . .: .... :.: .: .: ..: .:.. ::::: :.
XP_011 LVLFSLDVKNLENFQLVEGVQEQVNAALLDYTMCNYPQQTEKFGQLLLRLPEIRAISMQA
420 430 440 450 460 470
460 470
pF1KE3 VNVPLEQLPLLFKVVLHSCKTSVGKE
XP_011 EEYLYYKHLNGDVPYNNLLIEMLHAKRA
480 490 500
479 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 17:15:03 2016 done: Mon Nov 7 17:15:05 2016
Total Scan time: 10.380 Total Display time: 0.060
Function used was FASTA [36.3.4 Apr, 2011]