Result of FASTA (omim) for
pFN21AE3202
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE3202, 471 aa
1>>>pF1KE3202 471 - 471 aa - 471 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.3129+/-0.000445; mu= 18.0489+/- 0.027
mean_var=70.9742+/-14.456, 0's: 0 Z-trim(109.8): 39 B-trim: 518 in 1/56
Lambda= 0.152238
statistics sampled from 18021 (18058) to 18021 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.582), E-opt: 0.2 (0.212), width: 16
Scan time: 5.940
The best scores are: opt bits E(85289)
NP_002616 (OMIM: 311790) 6-phosphofructo-2-kinase/ ( 471) 3150 701.5 1.2e-201
XP_016885067 (OMIM: 311790) PREDICTED: 6-phosphofr ( 449) 2679 598.1 1.7e-170
XP_016885065 (OMIM: 311790) PREDICTED: 6-phosphofr ( 500) 2679 598.1 1.8e-170
NP_001258734 (OMIM: 311790) 6-phosphofructo-2-kina ( 406) 2664 594.7 1.5e-169
NP_001258733 (OMIM: 311790) 6-phosphofructo-2-kina ( 449) 2509 560.7 2.9e-159
NP_004558 (OMIM: 605320) 6-phosphofructo-2-kinase/ ( 469) 2398 536.4 6.5e-152
NP_001304064 (OMIM: 605320) 6-phosphofructo-2-kina ( 462) 2338 523.2 6e-148
NP_001304065 (OMIM: 605320) 6-phosphofructo-2-kina ( 458) 2330 521.4 2e-147
XP_016862105 (OMIM: 605320) PREDICTED: 6-phosphofr ( 457) 2329 521.2 2.3e-147
XP_011532131 (OMIM: 605320) PREDICTED: 6-phosphofr ( 471) 2329 521.2 2.4e-147
NP_001304063 (OMIM: 605320) 6-phosphofructo-2-kina ( 498) 2329 521.2 2.5e-147
XP_016885066 (OMIM: 311790) PREDICTED: 6-phosphofr ( 468) 2267 507.6 3e-143
XP_005252521 (OMIM: 605319) PREDICTED: 6-phosphofr ( 462) 2235 500.6 3.8e-141
XP_016862106 (OMIM: 605320) PREDICTED: 6-phosphofr ( 453) 2234 500.3 4.4e-141
XP_016862103 (OMIM: 605320) PREDICTED: 6-phosphofr ( 493) 2233 500.1 5.5e-141
NP_001300992 (OMIM: 605319) 6-phosphofructo-2-kina ( 514) 2226 498.6 1.6e-140
NP_004557 (OMIM: 605319) 6-phosphofructo-2-kinase/ ( 520) 2226 498.6 1.7e-140
XP_016871814 (OMIM: 605319) PREDICTED: 6-phosphofr ( 568) 2226 498.6 1.8e-140
NP_001309945 (OMIM: 605319) 6-phosphofructo-2-kina ( 494) 2165 485.2 1.7e-136
NP_001138915 (OMIM: 605319) 6-phosphofructo-2-kina ( 500) 2165 485.2 1.7e-136
XP_016871816 (OMIM: 605319) PREDICTED: 6-phosphofr ( 548) 2165 485.2 1.9e-136
NP_001269559 (OMIM: 605319) 6-phosphofructo-2-kina ( 534) 2164 485.0 2.1e-136
NP_001018063 (OMIM: 171835) 6-phosphofructo-2-kina ( 471) 2159 483.9 4.1e-136
NP_006203 (OMIM: 171835) 6-phosphofructo-2-kinase/ ( 505) 2156 483.2 6.9e-136
NP_001304067 (OMIM: 605320) 6-phosphofructo-2-kina ( 278) 1575 355.5 1.1e-97
NP_001304066 (OMIM: 605320) 6-phosphofructo-2-kina ( 434) 1547 349.4 1.1e-95
XP_011517795 (OMIM: 605319) PREDICTED: 6-phosphofr ( 427) 1503 339.8 9e-93
XP_016871817 (OMIM: 605319) PREDICTED: 6-phosphofr ( 533) 1503 339.8 1.1e-92
XP_016871818 (OMIM: 605319) PREDICTED: 6-phosphofr ( 501) 1488 336.5 1e-91
XP_016871815 (OMIM: 605319) PREDICTED: 6-phosphofr ( 549) 1488 336.5 1.1e-91
XP_016862104 (OMIM: 605320) PREDICTED: 6-phosphofr ( 463) 1478 334.3 4.3e-91
NP_001309946 (OMIM: 605319) 6-phosphofructo-2-kina ( 337) 1418 321.0 3.1e-87
XP_005273219 (OMIM: 171835) PREDICTED: 6-phosphofr ( 263) 1172 266.9 4.7e-71
>>NP_002616 (OMIM: 311790) 6-phosphofructo-2-kinase/fruc (471 aa)
initn: 3150 init1: 3150 opt: 3150 Z-score: 3740.9 bits: 701.5 E(85289): 1.2e-201
Smith-Waterman score: 3150; 100.0% identity (100.0% similar) in 471 aa overlap (1-471:1-471)
10 20 30 40 50 60
pF1KE3 MSPEMGELTQTRLQKIWIPHSSGSSRLQRRRGSSIPQFTNSPTMVIMVGLPARGKTYIST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MSPEMGELTQTRLQKIWIPHSSGSSRLQRRRGSSIPQFTNSPTMVIMVGLPARGKTYIST
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 KLTRYLNWIGTPTKVFNLGQYRREAVSYKNYEFFLPDNMEALQIRKQCALAALKDVHNYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 KLTRYLNWIGTPTKVFNLGQYRREAVSYKNYEFFLPDNMEALQIRKQCALAALKDVHNYL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 SHEEGHVAVFDATNTTRERRSLILQFAKEHGYKVFFIESICNDPGIIAENIRQVKLGSPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 SHEEGHVAVFDATNTTRERRSLILQFAKEHGYKVFFIESICNDPGIIAENIRQVKLGSPD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 YIDCDREKVLEDFLKRIECYEVNYQPLDEELDSHLSYIKIFDVGTRYMVNRVQDHIQSRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 YIDCDREKVLEDFLKRIECYEVNYQPLDEELDSHLSYIKIFDVGTRYMVNRVQDHIQSRT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 VYYLMNIHVTPRSIYLCRHGESELNIRGRIGGDSGLSVRGKQYAYALANFIQSQGISSLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 VYYLMNIHVTPRSIYLCRHGESELNIRGRIGGDSGLSVRGKQYAYALANFIQSQGISSLK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 VWTSHMKRTIQTAEALGVPYEQWKALNEIDAGVCEEMTYEEIQEHYPEEFALRDQDKYRY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 VWTSHMKRTIQTAEALGVPYEQWKALNEIDAGVCEEMTYEEIQEHYPEEFALRDQDKYRY
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 RYPKGESYEDLVQRLEPVIMELERQENVLVICHQAVMRCLLAYFLDKSSDELPYLKCPLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 RYPKGESYEDLVQRLEPVIMELERQENVLVICHQAVMRCLLAYFLDKSSDELPYLKCPLH
370 380 390 400 410 420
430 440 450 460 470
pF1KE3 TVLKLTPVAYGCKVESIYLNVEAVNTHREKPENVDITREPEEALDTVPAHY
:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 TVLKLTPVAYGCKVESIYLNVEAVNTHREKPENVDITREPEEALDTVPAHY
430 440 450 460 470
>>XP_016885067 (OMIM: 311790) PREDICTED: 6-phosphofructo (449 aa)
initn: 2847 init1: 2658 opt: 2679 Z-score: 3182.1 bits: 598.1 E(85289): 1.7e-170
Smith-Waterman score: 2809; 95.3% identity (95.3% similar) in 449 aa overlap (44-471:1-449)
20 30 40 50 60 70
pF1KE3 QKIWIPHSSGSSRLQRRRGSSIPQFTNSPTMVIMVGLPARGKTYISTKLTRYLNWIGTPT
::::::::::::::::::::::::::::::
XP_016 MVIMVGLPARGKTYISTKLTRYLNWIGTPT
10 20 30
80 90 100 110
pF1KE3 K---------------------VFNLGQYRREAVSYKNYEFFLPDNMEALQIRKQCALAA
: ::::::::::::::::::::::::::::::::::::::
XP_016 KARTFFWPLGSSQPLHWHSLLSVFNLGQYRREAVSYKNYEFFLPDNMEALQIRKQCALAA
40 50 60 70 80 90
120 130 140 150 160 170
pF1KE3 LKDVHNYLSHEEGHVAVFDATNTTRERRSLILQFAKEHGYKVFFIESICNDPGIIAENIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKDVHNYLSHEEGHVAVFDATNTTRERRSLILQFAKEHGYKVFFIESICNDPGIIAENIR
100 110 120 130 140 150
180 190 200 210 220 230
pF1KE3 QVKLGSPDYIDCDREKVLEDFLKRIECYEVNYQPLDEELDSHLSYIKIFDVGTRYMVNRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QVKLGSPDYIDCDREKVLEDFLKRIECYEVNYQPLDEELDSHLSYIKIFDVGTRYMVNRV
160 170 180 190 200 210
240 250 260 270 280 290
pF1KE3 QDHIQSRTVYYLMNIHVTPRSIYLCRHGESELNIRGRIGGDSGLSVRGKQYAYALANFIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QDHIQSRTVYYLMNIHVTPRSIYLCRHGESELNIRGRIGGDSGLSVRGKQYAYALANFIQ
220 230 240 250 260 270
300 310 320 330 340 350
pF1KE3 SQGISSLKVWTSHMKRTIQTAEALGVPYEQWKALNEIDAGVCEEMTYEEIQEHYPEEFAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SQGISSLKVWTSHMKRTIQTAEALGVPYEQWKALNEIDAGVCEEMTYEEIQEHYPEEFAL
280 290 300 310 320 330
360 370 380 390 400 410
pF1KE3 RDQDKYRYRYPKGESYEDLVQRLEPVIMELERQENVLVICHQAVMRCLLAYFLDKSSDEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RDQDKYRYRYPKGESYEDLVQRLEPVIMELERQENVLVICHQAVMRCLLAYFLDKSSDEL
340 350 360 370 380 390
420 430 440 450 460 470
pF1KE3 PYLKCPLHTVLKLTPVAYGCKVESIYLNVEAVNTHREKPENVDITREPEEALDTVPAHY
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PYLKCPLHTVLKLTPVAYGCKVESIYLNVEAVNTHREKPENVDITREPEEALDTVPAHY
400 410 420 430 440
>>XP_016885065 (OMIM: 311790) PREDICTED: 6-phosphofructo (500 aa)
initn: 3136 init1: 2658 opt: 2679 Z-score: 3181.5 bits: 598.1 E(85289): 1.8e-170
Smith-Waterman score: 3098; 95.7% identity (95.7% similar) in 492 aa overlap (1-471:9-500)
10 20 30 40 50
pF1KE3 MSPEMGELTQTRLQKIWIPHSSGSSRLQRRRGSSIPQFTNSPTMVIMVGLPA
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSFGATPKMSPEMGELTQTRLQKIWIPHSSGSSRLQRRRGSSIPQFTNSPTMVIMVGLPA
10 20 30 40 50 60
60 70 80 90
pF1KE3 RGKTYISTKLTRYLNWIGTPTK---------------------VFNLGQYRREAVSYKNY
:::::::::::::::::::::: :::::::::::::::::
XP_016 RGKTYISTKLTRYLNWIGTPTKARTFFWPLGSSQPLHWHSLLSVFNLGQYRREAVSYKNY
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE3 EFFLPDNMEALQIRKQCALAALKDVHNYLSHEEGHVAVFDATNTTRERRSLILQFAKEHG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EFFLPDNMEALQIRKQCALAALKDVHNYLSHEEGHVAVFDATNTTRERRSLILQFAKEHG
130 140 150 160 170 180
160 170 180 190 200 210
pF1KE3 YKVFFIESICNDPGIIAENIRQVKLGSPDYIDCDREKVLEDFLKRIECYEVNYQPLDEEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YKVFFIESICNDPGIIAENIRQVKLGSPDYIDCDREKVLEDFLKRIECYEVNYQPLDEEL
190 200 210 220 230 240
220 230 240 250 260 270
pF1KE3 DSHLSYIKIFDVGTRYMVNRVQDHIQSRTVYYLMNIHVTPRSIYLCRHGESELNIRGRIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DSHLSYIKIFDVGTRYMVNRVQDHIQSRTVYYLMNIHVTPRSIYLCRHGESELNIRGRIG
250 260 270 280 290 300
280 290 300 310 320 330
pF1KE3 GDSGLSVRGKQYAYALANFIQSQGISSLKVWTSHMKRTIQTAEALGVPYEQWKALNEIDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GDSGLSVRGKQYAYALANFIQSQGISSLKVWTSHMKRTIQTAEALGVPYEQWKALNEIDA
310 320 330 340 350 360
340 350 360 370 380 390
pF1KE3 GVCEEMTYEEIQEHYPEEFALRDQDKYRYRYPKGESYEDLVQRLEPVIMELERQENVLVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GVCEEMTYEEIQEHYPEEFALRDQDKYRYRYPKGESYEDLVQRLEPVIMELERQENVLVI
370 380 390 400 410 420
400 410 420 430 440 450
pF1KE3 CHQAVMRCLLAYFLDKSSDELPYLKCPLHTVLKLTPVAYGCKVESIYLNVEAVNTHREKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CHQAVMRCLLAYFLDKSSDELPYLKCPLHTVLKLTPVAYGCKVESIYLNVEAVNTHREKP
430 440 450 460 470 480
460 470
pF1KE3 ENVDITREPEEALDTVPAHY
::::::::::::::::::::
XP_016 ENVDITREPEEALDTVPAHY
490 500
>>NP_001258734 (OMIM: 311790) 6-phosphofructo-2-kinase/f (406 aa)
initn: 2664 init1: 2664 opt: 2664 Z-score: 3165.0 bits: 594.7 E(85289): 1.5e-169
Smith-Waterman score: 2664; 100.0% identity (100.0% similar) in 398 aa overlap (74-471:9-406)
50 60 70 80 90 100
pF1KE3 MVIMVGLPARGKTYISTKLTRYLNWIGTPTKVFNLGQYRREAVSYKNYEFFLPDNMEALQ
::::::::::::::::::::::::::::::
NP_001 MEEKTSRIKVFNLGQYRREAVSYKNYEFFLPDNMEALQ
10 20 30
110 120 130 140 150 160
pF1KE3 IRKQCALAALKDVHNYLSHEEGHVAVFDATNTTRERRSLILQFAKEHGYKVFFIESICND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IRKQCALAALKDVHNYLSHEEGHVAVFDATNTTRERRSLILQFAKEHGYKVFFIESICND
40 50 60 70 80 90
170 180 190 200 210 220
pF1KE3 PGIIAENIRQVKLGSPDYIDCDREKVLEDFLKRIECYEVNYQPLDEELDSHLSYIKIFDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PGIIAENIRQVKLGSPDYIDCDREKVLEDFLKRIECYEVNYQPLDEELDSHLSYIKIFDV
100 110 120 130 140 150
230 240 250 260 270 280
pF1KE3 GTRYMVNRVQDHIQSRTVYYLMNIHVTPRSIYLCRHGESELNIRGRIGGDSGLSVRGKQY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GTRYMVNRVQDHIQSRTVYYLMNIHVTPRSIYLCRHGESELNIRGRIGGDSGLSVRGKQY
160 170 180 190 200 210
290 300 310 320 330 340
pF1KE3 AYALANFIQSQGISSLKVWTSHMKRTIQTAEALGVPYEQWKALNEIDAGVCEEMTYEEIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AYALANFIQSQGISSLKVWTSHMKRTIQTAEALGVPYEQWKALNEIDAGVCEEMTYEEIQ
220 230 240 250 260 270
350 360 370 380 390 400
pF1KE3 EHYPEEFALRDQDKYRYRYPKGESYEDLVQRLEPVIMELERQENVLVICHQAVMRCLLAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EHYPEEFALRDQDKYRYRYPKGESYEDLVQRLEPVIMELERQENVLVICHQAVMRCLLAY
280 290 300 310 320 330
410 420 430 440 450 460
pF1KE3 FLDKSSDELPYLKCPLHTVLKLTPVAYGCKVESIYLNVEAVNTHREKPENVDITREPEEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FLDKSSDELPYLKCPLHTVLKLTPVAYGCKVESIYLNVEAVNTHREKPENVDITREPEEA
340 350 360 370 380 390
470
pF1KE3 LDTVPAHY
::::::::
NP_001 LDTVPAHY
400
>>NP_001258733 (OMIM: 311790) 6-phosphofructo-2-kinase/f (449 aa)
initn: 2987 init1: 2509 opt: 2509 Z-score: 2980.3 bits: 560.7 E(85289): 2.9e-159
Smith-Waterman score: 2947; 95.3% identity (95.3% similar) in 471 aa overlap (1-471:1-449)
10 20 30 40 50 60
pF1KE3 MSPEMGELTQTRLQKIWIPHSSGSSRLQRRRGSSIPQFTNSPTMVIMVGLPARGKTYIST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSPEMGELTQTRLQKIWIPHSSGSSRLQRRRGSSIPQFTNSPTMVIMVGLPARGKTYIST
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 KLTRYLNWIGTPTKVFNLGQYRREAVSYKNYEFFLPDNMEALQIRKQCALAALKDVHNYL
:::::::::::::: ::::::::::::::::::::::::
NP_001 KLTRYLNWIGTPTK----------------------DNMEALQIRKQCALAALKDVHNYL
70 80 90
130 140 150 160 170 180
pF1KE3 SHEEGHVAVFDATNTTRERRSLILQFAKEHGYKVFFIESICNDPGIIAENIRQVKLGSPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SHEEGHVAVFDATNTTRERRSLILQFAKEHGYKVFFIESICNDPGIIAENIRQVKLGSPD
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE3 YIDCDREKVLEDFLKRIECYEVNYQPLDEELDSHLSYIKIFDVGTRYMVNRVQDHIQSRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YIDCDREKVLEDFLKRIECYEVNYQPLDEELDSHLSYIKIFDVGTRYMVNRVQDHIQSRT
160 170 180 190 200 210
250 260 270 280 290 300
pF1KE3 VYYLMNIHVTPRSIYLCRHGESELNIRGRIGGDSGLSVRGKQYAYALANFIQSQGISSLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VYYLMNIHVTPRSIYLCRHGESELNIRGRIGGDSGLSVRGKQYAYALANFIQSQGISSLK
220 230 240 250 260 270
310 320 330 340 350 360
pF1KE3 VWTSHMKRTIQTAEALGVPYEQWKALNEIDAGVCEEMTYEEIQEHYPEEFALRDQDKYRY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VWTSHMKRTIQTAEALGVPYEQWKALNEIDAGVCEEMTYEEIQEHYPEEFALRDQDKYRY
280 290 300 310 320 330
370 380 390 400 410 420
pF1KE3 RYPKGESYEDLVQRLEPVIMELERQENVLVICHQAVMRCLLAYFLDKSSDELPYLKCPLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RYPKGESYEDLVQRLEPVIMELERQENVLVICHQAVMRCLLAYFLDKSSDELPYLKCPLH
340 350 360 370 380 390
430 440 450 460 470
pF1KE3 TVLKLTPVAYGCKVESIYLNVEAVNTHREKPENVDITREPEEALDTVPAHY
:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TVLKLTPVAYGCKVESIYLNVEAVNTHREKPENVDITREPEEALDTVPAHY
400 410 420 430 440
>>NP_004558 (OMIM: 605320) 6-phosphofructo-2-kinase/fruc (469 aa)
initn: 2396 init1: 2075 opt: 2398 Z-score: 2848.3 bits: 536.4 E(85289): 6.5e-152
Smith-Waterman score: 2398; 75.4% identity (90.9% similar) in 471 aa overlap (2-470:3-468)
10 20 30 40 50
pF1KE3 MSPEMGELTQTRLQKIWIPHSSGSSRLQR-RRGSSIPQFTNSPTMVIMVGLPARGKTYI
::. ::::. :.:::.:.:.: :. .:: . :: ::...::::::::::::
NP_004 MASPR--ELTQNPLKKIWMPYSNGRPALHACQRGVCM---TNCPTLIVMVGLPARGKTYI
10 20 30 40 50
60 70 80 90 100 110
pF1KE3 STKLTRYLNWIGTPTKVFNLGQYRREAV-SYKNYEFFLPDNMEALQIRKQCALAALKDVH
: ::::::::::.::. ::.:::::..: .::..::::::: :.:.::::::::::.::.
NP_004 SKKLTRYLNWIGVPTREFNVGQYRRDVVKTYKSFEFFLPDNEEGLKIRKQCALAALRDVR
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE3 NYLSHEEGHVAVFDATNTTRERRSLILQFAKEHGYKVFFIESICNDPGIIAENIRQVKLG
.::.: ::::::::::::::::. :..:....:::.::.:::: :: .:: :: :::::
NP_004 RFLSEEGGHVAVFDATNTTRERRATIFNFGEQNGYKTFFVESICVDPEVIAANIVQVKLG
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE3 SPDYIDCDREKVLEDFLKRIECYEVNYQPLDEELDSHLSYIKIFDVGTRYMVNRVQDHIQ
::::.. : ... :::..:::::: .:. :::.:: ::::::.::: :.:::: ::::
NP_004 SPDYVNRDSDEATEDFMRRIECYENSYESLDEDLDRDLSYIKIMDVGQSYVVNRVADHIQ
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE3 SRTVYYLMNIHVTPRSIYLCRHGESELNIRGRIGGDSGLSVRGKQYAYALANFIQSQGIS
:: :::::::::::::::::::::::::..:::::: ::: ::...: .::.::..:.:.
NP_004 SRIVYYLMNIHVTPRSIYLCRHGESELNLKGRIGGDPGLSPRGREFAKSLAQFISDQNIK
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE3 SLKVWTSHMKRTIQTAEALGVPYEQWKALNEIDAGVCEEMTYEEIQEHYPEEFALRDQDK
.::::::.:::::::::::::::::::.::::::::::::::::::..:: :::::::::
NP_004 DLKVWTSQMKRTIQTAEALGVPYEQWKVLNEIDAGVCEEMTYEEIQDNYPLEFALRDQDK
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE3 YRYRYPKGESYEDLVQRLEPVIMELERQENVLVICHQAVMRCLLAYFLDKSSDELPYLKC
::::::::::::::::::::::::::::::::::::::::::::::::::....::::::
NP_004 YRYRYPKGESYEDLVQRLEPVIMELERQENVLVICHQAVMRCLLAYFLDKAAEQLPYLKC
360 370 380 390 400 410
420 430 440 450 460 470
pF1KE3 PLHTVLKLTPVAYGCKVESIYLNVEAVNTHREKPENVDITREPEEALDTVPAHY
::::::::::::::::::::.::: ::::::..:.::::.: ::::: :::::
NP_004 PLHTVLKLTPVAYGCKVESIFLNVAAVNTHRDRPQNVDISRPPEEALVTVPAHQ
420 430 440 450 460
>>NP_001304064 (OMIM: 605320) 6-phosphofructo-2-kinase/f (462 aa)
initn: 1510 init1: 1189 opt: 2338 Z-score: 2777.2 bits: 523.2 E(85289): 6e-148
Smith-Waterman score: 2338; 74.1% identity (89.4% similar) in 471 aa overlap (2-470:3-461)
10 20 30 40 50
pF1KE3 MSPEMGELTQTRLQKIWIPHSSGSSRLQR-RRGSSIPQFTNSPTMVIMVGLPARGKTYI
::. ::::. :.:::.:.:.: :. .:: . :: ::...::::::::::::
NP_001 MASPR--ELTQNPLKKIWMPYSNGRPALHACQRGVCM---TNCPTLIVMVGLPARGKTYI
10 20 30 40 50
60 70 80 90 100 110
pF1KE3 STKLTRYLNWIGTPTKVFNLGQYRREAV-SYKNYEFFLPDNMEALQIRKQCALAALKDVH
: ::::::::::.::. ::.:::::..: .::..::::::: :.:.::::::::::.::.
NP_001 SKKLTRYLNWIGVPTREFNVGQYRRDVVKTYKSFEFFLPDNEEGLKIRKQCALAALRDVR
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE3 NYLSHEEGHVAVFDATNTTRERRSLILQFAKEHGYKVFFIESICNDPGIIAENIRQVKLG
.::.: ::::::::::::::::. :..:....:::.::.:::: :: .:: :: :::::
NP_001 RFLSEEGGHVAVFDATNTTRERRATIFNFGEQNGYKTFFVESICVDPEVIAANIVQVKLG
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE3 SPDYIDCDREKVLEDFLKRIECYEVNYQPLDEELDSHLSYIKIFDVGTRYMVNRVQDHIQ
::::.. : ... :::..:::::: .:. :::.:: ::::::.::: :.:::: ::::
NP_001 SPDYVNRDSDEATEDFMRRIECYENSYESLDEDLDRDLSYIKIMDVGQSYVVNRVADHIQ
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE3 SRTVYYLMNIHVTPRSIYLCRHGESELNIRGRIGGDSGLSVRGKQYAYALANFIQSQGIS
:: :::::::::::::::::::::::::..:::::: ::: ::...: .::.::..:.:.
NP_001 SRIVYYLMNIHVTPRSIYLCRHGESELNLKGRIGGDPGLSPRGREFAKSLAQFISDQNIK
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE3 SLKVWTSHMKRTIQTAEALGVPYEQWKALNEIDAGVCEEMTYEEIQEHYPEEFALRDQDK
.::::::.::::::::::::::::::: ::::::::::::..:: :::::::::
NP_001 DLKVWTSQMKRTIQTAEALGVPYEQWK-------GVCEEMTYEEIQDNYPLEFALRDQDK
300 310 320 330 340
360 370 380 390 400 410
pF1KE3 YRYRYPKGESYEDLVQRLEPVIMELERQENVLVICHQAVMRCLLAYFLDKSSDELPYLKC
::::::::::::::::::::::::::::::::::::::::::::::::::....::::::
NP_001 YRYRYPKGESYEDLVQRLEPVIMELERQENVLVICHQAVMRCLLAYFLDKAAEQLPYLKC
350 360 370 380 390 400
420 430 440 450 460 470
pF1KE3 PLHTVLKLTPVAYGCKVESIYLNVEAVNTHREKPENVDITREPEEALDTVPAHY
::::::::::::::::::::.::: ::::::..:.::::.: ::::: :::::
NP_001 PLHTVLKLTPVAYGCKVESIFLNVAAVNTHRDRPQNVDISRPPEEALVTVPAHQ
410 420 430 440 450 460
>>NP_001304065 (OMIM: 605320) 6-phosphofructo-2-kinase/f (458 aa)
initn: 2327 init1: 2075 opt: 2330 Z-score: 2767.7 bits: 521.4 E(85289): 2e-147
Smith-Waterman score: 2330; 76.7% identity (91.3% similar) in 450 aa overlap (23-470:8-457)
10 20 30 40 50
pF1KE3 MSPEMGELTQTRLQKIWIPHSSGSSRLQRRRGSSIPQ-FTNSPTMVIMVGLPARGKTYIS
::: . ::: .:: ::...:::::::::::::
NP_001 MDRGSLGGSSLTDLGPGSSRRVCMTNCPTLIVMVGLPARGKTYIS
10 20 30 40
60 70 80 90 100 110
pF1KE3 TKLTRYLNWIGTPTKVFNLGQYRREAV-SYKNYEFFLPDNMEALQIRKQCALAALKDVHN
::::::::::.::. ::.:::::..: .::..::::::: :.:.::::::::::.::.
NP_001 KKLTRYLNWIGVPTREFNVGQYRRDVVKTYKSFEFFLPDNEEGLKIRKQCALAALRDVRR
50 60 70 80 90 100
120 130 140 150 160 170
pF1KE3 YLSHEEGHVAVFDATNTTRERRSLILQFAKEHGYKVFFIESICNDPGIIAENIRQVKLGS
.::.: ::::::::::::::::. :..:....:::.::.:::: :: .:: :: ::::::
NP_001 FLSEEGGHVAVFDATNTTRERRATIFNFGEQNGYKTFFVESICVDPEVIAANIVQVKLGS
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE3 PDYIDCDREKVLEDFLKRIECYEVNYQPLDEELDSHLSYIKIFDVGTRYMVNRVQDHIQS
:::.. : ... :::..:::::: .:. :::.:: ::::::.::: :.:::: :::::
NP_001 PDYVNRDSDEATEDFMRRIECYENSYESLDEDLDRDLSYIKIMDVGQSYVVNRVADHIQS
170 180 190 200 210 220
240 250 260 270 280 290
pF1KE3 RTVYYLMNIHVTPRSIYLCRHGESELNIRGRIGGDSGLSVRGKQYAYALANFIQSQGISS
: :::::::::::::::::::::::::..:::::: ::: ::...: .::.::..:.:..
NP_001 RIVYYLMNIHVTPRSIYLCRHGESELNLKGRIGGDPGLSPRGREFAKSLAQFISDQNIKD
230 240 250 260 270 280
300 310 320 330 340 350
pF1KE3 LKVWTSHMKRTIQTAEALGVPYEQWKALNEIDAGVCEEMTYEEIQEHYPEEFALRDQDKY
::::::.:::::::::::::::::::.::::::::::::::::::..:: ::::::::::
NP_001 LKVWTSQMKRTIQTAEALGVPYEQWKVLNEIDAGVCEEMTYEEIQDNYPLEFALRDQDKY
290 300 310 320 330 340
360 370 380 390 400 410
pF1KE3 RYRYPKGESYEDLVQRLEPVIMELERQENVLVICHQAVMRCLLAYFLDKSSDELPYLKCP
:::::::::::::::::::::::::::::::::::::::::::::::::....:::::::
NP_001 RYRYPKGESYEDLVQRLEPVIMELERQENVLVICHQAVMRCLLAYFLDKAAEQLPYLKCP
350 360 370 380 390 400
420 430 440 450 460 470
pF1KE3 LHTVLKLTPVAYGCKVESIYLNVEAVNTHREKPENVDITREPEEALDTVPAHY
:::::::::::::::::::.::: ::::::..:.::::.: ::::: :::::
NP_001 LHTVLKLTPVAYGCKVESIFLNVAAVNTHRDRPQNVDISRPPEEALVTVPAHQ
410 420 430 440 450
>>XP_016862105 (OMIM: 605320) PREDICTED: 6-phosphofructo (457 aa)
initn: 2327 init1: 2075 opt: 2329 Z-score: 2766.6 bits: 521.2 E(85289): 2.3e-147
Smith-Waterman score: 2329; 78.3% identity (93.1% similar) in 433 aa overlap (39-470:24-456)
10 20 30 40 50 60
pF1KE3 TQTRLQKIWIPHSSGSSRLQRRRGSSIPQFTNSPTMVIMVGLPARGKTYISTKLTRYLNW
:: ::...::::::::::::: ::::::::
XP_016 MRILDPGLKNWAHLFQNGRVVCMTNCPTLIVMVGLPARGKTYISKKLTRYLNW
10 20 30 40 50
70 80 90 100 110 120
pF1KE3 IGTPTKVFNLGQYRREAV-SYKNYEFFLPDNMEALQIRKQCALAALKDVHNYLSHEEGHV
::.::. ::.:::::..: .::..::::::: :.:.::::::::::.::. .::.: :::
XP_016 IGVPTREFNVGQYRRDVVKTYKSFEFFLPDNEEGLKIRKQCALAALRDVRRFLSEEGGHV
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE3 AVFDATNTTRERRSLILQFAKEHGYKVFFIESICNDPGIIAENIRQVKLGSPDYIDCDRE
:::::::::::::. :..:....:::.::.:::: :: .:: :: :::::::::.. : .
XP_016 AVFDATNTTRERRATIFNFGEQNGYKTFFVESICVDPEVIAANIVQVKLGSPDYVNRDSD
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE3 KVLEDFLKRIECYEVNYQPLDEELDSHLSYIKIFDVGTRYMVNRVQDHIQSRTVYYLMNI
.. :::..:::::: .:. :::.:: ::::::.::: :.:::: :::::: :::::::
XP_016 EATEDFMRRIECYENSYESLDEDLDRDLSYIKIMDVGQSYVVNRVADHIQSRIVYYLMNI
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE3 HVTPRSIYLCRHGESELNIRGRIGGDSGLSVRGKQYAYALANFIQSQGISSLKVWTSHMK
::::::::::::::::::..:::::: ::: ::...: .::.::..:.:..::::::.::
XP_016 HVTPRSIYLCRHGESELNLKGRIGGDPGLSPRGREFAKSLAQFISDQNIKDLKVWTSQMK
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE3 RTIQTAEALGVPYEQWKALNEIDAGVCEEMTYEEIQEHYPEEFALRDQDKYRYRYPKGES
:::::::::::::::::.::::::::::::::::::..:: :::::::::::::::::::
XP_016 RTIQTAEALGVPYEQWKVLNEIDAGVCEEMTYEEIQDNYPLEFALRDQDKYRYRYPKGES
300 310 320 330 340 350
370 380 390 400 410 420
pF1KE3 YEDLVQRLEPVIMELERQENVLVICHQAVMRCLLAYFLDKSSDELPYLKCPLHTVLKLTP
::::::::::::::::::::::::::::::::::::::::....::::::::::::::::
XP_016 YEDLVQRLEPVIMELERQENVLVICHQAVMRCLLAYFLDKAAEQLPYLKCPLHTVLKLTP
360 370 380 390 400 410
430 440 450 460 470
pF1KE3 VAYGCKVESIYLNVEAVNTHREKPENVDITREPEEALDTVPAHY
::::::::::.::: ::::::..:.::::.: ::::: :::::
XP_016 VAYGCKVESIFLNVAAVNTHRDRPQNVDISRPPEEALVTVPAHQ
420 430 440 450
>>XP_011532131 (OMIM: 605320) PREDICTED: 6-phosphofructo (471 aa)
initn: 2327 init1: 2075 opt: 2329 Z-score: 2766.4 bits: 521.2 E(85289): 2.4e-147
Smith-Waterman score: 2329; 78.3% identity (93.1% similar) in 433 aa overlap (39-470:38-470)
10 20 30 40 50 60
pF1KE3 TQTRLQKIWIPHSSGSSRLQRRRGSSIPQFTNSPTMVIMVGLPARGKTYISTKLTRYLNW
:: ::...::::::::::::: ::::::::
XP_011 VLNKHKATEGWDVRESQWCAPRPRHMVVCMTNCPTLIVMVGLPARGKTYISKKLTRYLNW
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE3 IGTPTKVFNLGQYRREAV-SYKNYEFFLPDNMEALQIRKQCALAALKDVHNYLSHEEGHV
::.::. ::.:::::..: .::..::::::: :.:.::::::::::.::. .::.: :::
XP_011 IGVPTREFNVGQYRRDVVKTYKSFEFFLPDNEEGLKIRKQCALAALRDVRRFLSEEGGHV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE3 AVFDATNTTRERRSLILQFAKEHGYKVFFIESICNDPGIIAENIRQVKLGSPDYIDCDRE
:::::::::::::. :..:....:::.::.:::: :: .:: :: :::::::::.. : .
XP_011 AVFDATNTTRERRATIFNFGEQNGYKTFFVESICVDPEVIAANIVQVKLGSPDYVNRDSD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE3 KVLEDFLKRIECYEVNYQPLDEELDSHLSYIKIFDVGTRYMVNRVQDHIQSRTVYYLMNI
.. :::..:::::: .:. :::.:: ::::::.::: :.:::: :::::: :::::::
XP_011 EATEDFMRRIECYENSYESLDEDLDRDLSYIKIMDVGQSYVVNRVADHIQSRIVYYLMNI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE3 HVTPRSIYLCRHGESELNIRGRIGGDSGLSVRGKQYAYALANFIQSQGISSLKVWTSHMK
::::::::::::::::::..:::::: ::: ::...: .::.::..:.:..::::::.::
XP_011 HVTPRSIYLCRHGESELNLKGRIGGDPGLSPRGREFAKSLAQFISDQNIKDLKVWTSQMK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE3 RTIQTAEALGVPYEQWKALNEIDAGVCEEMTYEEIQEHYPEEFALRDQDKYRYRYPKGES
:::::::::::::::::.::::::::::::::::::..:: :::::::::::::::::::
XP_011 RTIQTAEALGVPYEQWKVLNEIDAGVCEEMTYEEIQDNYPLEFALRDQDKYRYRYPKGES
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE3 YEDLVQRLEPVIMELERQENVLVICHQAVMRCLLAYFLDKSSDELPYLKCPLHTVLKLTP
::::::::::::::::::::::::::::::::::::::::....::::::::::::::::
XP_011 YEDLVQRLEPVIMELERQENVLVICHQAVMRCLLAYFLDKAAEQLPYLKCPLHTVLKLTP
370 380 390 400 410 420
430 440 450 460 470
pF1KE3 VAYGCKVESIYLNVEAVNTHREKPENVDITREPEEALDTVPAHY
::::::::::.::: ::::::..:.::::.: ::::: :::::
XP_011 VAYGCKVESIFLNVAAVNTHRDRPQNVDISRPPEEALVTVPAHQ
430 440 450 460 470
471 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Mon Nov 7 17:32:51 2016 done: Mon Nov 7 17:32:52 2016
Total Scan time: 5.940 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]